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1,211 results on '"Zhang, Jinfang"'

102. Cyclin DCDK4 kinase destabilizes PD-L1 via cullin 3SPOP to control cancer immune surveillance

Author

Zhang, Jinfang, Bu, Xia, Wang, Haizhen, Zhu, Yasheng, Geng, Yan, Nihira, Naoe Taira, Tan, Yuyong, Ci, Yanpeng, Wu, Fei, Dai, Xiangpeng, Guo, Jianping, Huang, Yu-Han, Fan, Caoqi, Ren, Shancheng, Sun, Yinghao, Freeman, Gordon J., Sicinski, Piotr, and Wei, Wenyi

Subjects
Cancer treatment -- Methods, Apoptosis -- Research, Phosphotransferases -- Physiological aspects, Cancer research, Ligands (Biochemistry) -- Physiological aspects, Immune response -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Author(s): Jinfang Zhang [1]; Xia Bu [2]; Haizhen Wang [3]; Yasheng Zhu [4]; Yan Geng [3]; Naoe Taira Nihira [1]; Yuyong Tan [1, 5]; Yanpeng Ci [1, 6]; Fei Wu [...]

Published
2018
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108. Data from The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function

Author

Wan, Lixin, primary, Chen, Ming, primary, Cao, Juxiang, primary, Dai, Xiangpeng, primary, Yin, Qing, primary, Zhang, Jinfang, primary, Song, Su-Jung, primary, Lu, Ying, primary, Liu, Jing, primary, Inuzuka, Hiroyuki, primary, Katon, Jesse M., primary, Berry, Kelsey, primary, Fung, Jacqueline, primary, Ng, Christopher, primary, Liu, Pengda, primary, Song, Min Sup, primary, Xue, Lian, primary, Bronson, Roderick T., primary, Kirschner, Marc W., primary, Cui, Rutao, primary, Pandolfi, Pier Paolo, primary, and Wei, Wenyi, primary

Published
2023
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110. Supplementary Methods, Figure Legends, Figures S1 - S7, Table S1 - Supplementary Figure S1 from The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function

Author

Wan, Lixin, primary, Chen, Ming, primary, Cao, Juxiang, primary, Dai, Xiangpeng, primary, Yin, Qing, primary, Zhang, Jinfang, primary, Song, Su-Jung, primary, Lu, Ying, primary, Liu, Jing, primary, Inuzuka, Hiroyuki, primary, Katon, Jesse M., primary, Berry, Kelsey, primary, Fung, Jacqueline, primary, Ng, Christopher, primary, Liu, Pengda, primary, Song, Min Sup, primary, Xue, Lian, primary, Bronson, Roderick T., primary, Kirschner, Marc W., primary, Cui, Rutao, primary, Pandolfi, Pier Paolo, primary, and Wei, Wenyi, primary

Published
2023
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116. A Case of Gangrenous Herpes Zoster Complicated with Candida albicans Infection

Author

Wang,Dongxue, Xu,Zhe, Zeng,Linxi, Zhang,Jinfang, Zhang,Guoqiang, Wang,Dongxue, Xu,Zhe, Zeng,Linxi, Zhang,Jinfang, and Zhang,Guoqiang

Abstract

Dongxue Wang,1,* Zhe Xu,2,* Linxi Zeng,1 Jinfang Zhang,1 Guoqiang Zhang1 1Department of Dermatology, The First Hospital of Hebei Medical University, Candidate Branch of National Clinical Research Center for Skin Diseases, Shijiazhuang, People’s Republic of China; 2Department of Dermatology, National Center for Children’s Health, Beijing Children’s Hospital, Capital Medical University, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Guoqiang Zhang, Department of Dermatology, the First Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, 050031, People’s Republic of China, Tel +86 18633888122, Email zlx090702@163.comBackground: Herpes zoster is a disease caused by varicella-zoster virus infection, which is characterized by dense clusters of vesicles distributed along unilateral bands of nerves and accompanied by neuralgia. Although the disease is self-limited, some patients may develop neurological, ocular, skin, or visceral complications.Case Presentation: We report a 65-year-old Chinese man with ulceration secondary to cutaneous blister rupture on the left lumbar abdomen, who was diagnosed with herpes zoster and did not respond to conventional treatment. Dermatological examination showed diffuse dark erythema with clear boundaries on his left waist and abdomen. Deep ulcers of different sizes were densely distributed with steep edges and relatively dry base, while yellow secretions and black scabs could be seen. Fungal microscopy showed a few pseudohyphae and clusters of spores. Meanwhile, the fungal culture of the secretions showed Candida albicans growth. Skin biopsy of the affected skin from the ulcer of the left abdomen revealed epidermal absence and clusters of spores in the superficial dermis. PAS staining was positive. The patient was diagnosed with gangrenous herpes zoster complicated with Candida albicans infection. After antifungal treatment based on the resul

Published
2023

128. Case report: Relapsed disseminated cutaneous herpes zoster successfully treated with brivudine.

Author

Feng, Mengdi, Zhang, Jinfang, and Zhang, Guoqiang

Subjects
*VARICELLA-zoster virus, *HERPES zoster, *TREATMENT effectiveness, *VIRAL antibodies, *DNA viruses, *NEPHROTIC syndrome
Abstract

A 64-year-old man presented with painful rash on the trunk and extremities for more than half a month. Nephrotic syndrome had been diagnosed 2 years ago and had been regularly treated with glucocorticoids and immunosuppressants. He developed herpes zoster 1 year ago. Laboratory investigation demonstrated varicella-zoster virus DNA (VZV-DNA), varicella-zoster virus IgM (VZV-IgM), and varicella-zoster virus antibody IgG (VZV-IgG) were all positive. After the clinical diagnosis of relapsed disseminated cutaneous herpes zoster had been confirmed, systemic therapy with brivudine 125 mg everyday was started. [ABSTRACT FROM AUTHOR]

Published
2023
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129. A new-AIE-ligand-based metal–organic framework "turn-on" sensor with extremely high sensitivity.

Author

Zhang, Jinfang, Li, Wenjing, Ren, Simeng, Zhao, Shunchang, Tao, Xingyu, Chen, Qinghan, Yin, Dejing, and Zhang, Chi

Subjects
*METAL-organic frameworks, *DETECTORS, *GEOTHERMAL resources, *DETECTION limit, *THERMAL stability
Abstract

Excessive Fe3+ and Bi3+ can cause serious hazards to human-beings and microorganisms. However, it remains a great challenge to exploit more efficient methods to detect them. In this work, a two-dimensional (2-D) metal–organic framework (MOF) [Cd(3-L)(NDA)(H2O)]n (1) (3-L = 3,3′-((9H-fluoren-9-ylidene)-methylene)dipyridine; H2NDA = 1,4-naphthalenedicarboxylic acid) was successfully fabricated by a new fluorenyl-containing aggregation-induced emission (AIE) functional ligand. 1 features a 2-D (4,4) network, and good water and thermal stabilities. In its stacking structure, the fluorene rings from neighboring layers overlap with each other in the opposite direction, and show very weak π–π interactions. Accordingly, 1 exhibits superior luminescence enhancement ("turn-on") sensing of Fe3+ and Bi3+ with extremely high sensitivity in aqueous media. The detection limits of 1 for Fe3+ and Bi3+ are 4.86 × 10−4 and 1.87 × 10−5 mM, respectively, which are significantly lower than the corresponding reported works (only 23.6% and 0.8%). Interestingly, it has obviously enhanced Bi3+ detecting ability because of the larger ionic radius of Bi3+. More importantly, this is the first MOF-based "turn-on" sensor for Bi3+ reported to date. [ABSTRACT FROM AUTHOR]

Published
2023
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137. The Effect of the Acidic Gas Pollutant on Wool Keratin Fiber Structure

Author

Jiang, Zhe, Bai, Rubing, Zhang, Jinfang, Li, Ende, Cui, Yifan, Zhang, Ning, Zhang, Nan, and Wang, Qiang

Subjects
Materials Science (miscellaneous)
Abstract

Increase in air pollution caused by acidic gases, such as nitrogen dioxide, call for the need to study potential effects on the structure of textile materials. Wool is a natural protein fiber which is easily damaged due to rich reaction positions and cross-linked bonds in the fiber. This study reports, for the first time, effect of nitrogen dioxide, as a model acid gas pollutant, on the structure of wool. On the macro level, wool fabric undergoes strength loss after incubation in nitrogen dioxide for 6 h. Furthermore, although there was no obvious difference on the surface morphology as shown by SEM analysis, FTIR and Raman tests showed that the probable damage mechanism is by hydrolysis of amino bond, and oxidation of tyrosine residues and disulfide bonds, which was ascertained using XPS and amino acid analysis. In addition, crystallinity degree and α-helix structure content decreased after nitrogen dioxide treatment as shown by XRD and NMR results. These findings show that nitrogen dioxide has significant effect on the structure of wool. The study offers a novel approach for investigation of the interaction between gas pollutants and protein fiber, and provide information for protection of textiles against similar pollutants.

Published
2022

138. Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4

Author

Dai, Xiangpeng, Gan, Wenjian, Li, Xiaoning, Wang, Shangqian, Zhang, Wei, Huang, Ling, Liu, Shengwu, Zhong, Qing, Guo, Jianping, Zhang, Jinfang, Chen, Ting, Shimizu, Kouhei, Beca, Francisco, Blattner, Mirjam, Vasudevan, Divya, Buckley, Dennis L, Qi, Jun, Buser, Lorenz, Liu, Pengda, Inuzuka, Hiroyuki, Beck, Andrew H, Wang, Liewei, Wild, Peter J, Garraway, Levi A, Rubin, Mark A, Barbieri, Christopher E, Wong, Kwok-Kin, Muthuswamy, Senthil K, Huang, Jiaoti, Chen, Yu, Bradner, James E, and Wei, Wenyi

Subjects
Gene mutation -- Physiological aspects -- Research, Drug resistance -- Genetic aspects -- Research, Prostate cancer -- Genetic aspects -- Drug therapy -- Research, Biological sciences, Health
Abstract

Author(s): Xiangpeng Dai [1]; Wenjian Gan [1]; Xiaoning Li [1, 2]; Shangqian Wang [3]; Wei Zhang [4, 5]; Ling Huang [6]; Shengwu Liu [7, 8]; Qing Zhong [9]; Jianping Guo [...]

Published
2017
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142. On Action Permutation and Progress for Partially Commutative Asynchronous Binary Sessions

Author

Yang, Zhenguo, Zhong, Farong, Zhang, Jinfang, Song, Tiantian, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Xiang, Yang, editor, Pathan, Mukaddim, editor, Tao, Xiaohui, editor, and Wang, Hua, editor

Published
2012
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143. A Polymorphic Type System with Progress for Binary Sessions

Author

Yang, Zhenguo, Zhong, Farong, Zhang, Jinfang, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Wang, Fu Lee, editor, Lei, Jingsheng, editor, Gong, Zhiguo, editor, and Luo, Xiangfeng, editor

Published
2012
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