P. Kim Streatfield, Wasif A. Khan, Abbas Bhuiya, Syed M.A. Hanifi, Nurul Alam, Mamadou Ouattara, Aboubakary Sanou, Ali Sié, Bruno Lankoandé, Abdramane B. Soura, Bassirou Bonfoh, Fabienne Jaeger, Eliezer K. Ngoran, Juerg Utzinger, Loko Abreha, Yohannes A. Melaku, Berhe Weldearegawi, Akosua Ansah, Abraham Hodgson, Abraham Oduro, Paul Welaga, Margaret Gyapong, Clement T. Narh, Solomon A. Narh-Bana, Shashi Kant, Puneet Misra, Sanjay K. Rai, Evasius Bauni, George Mochamah, Carolyne Ndila, Thomas N. Williams, Mary J. Hamel, Emmanuel Ngulukyo, Frank O. Odhiambo, Maquins Sewe, Donatien Beguy, Alex Ezeh, Samuel Oti, Aldiouma Diallo, Laetitia Douillot, Cheikh Sokhna, Valérie Delaunay, Mark A. Collinson, Chodziwadziwa W. Kabudula, Kathleen Kahn, Kobus Herbst, Joël Mossong, Nguyen T.K. Chuc, Martin Bangha, Osman A. Sankoh, Peter Byass, Vrije Universiteit Medical Centre (VUMC), Vrije Universiteit Amsterdam [Amsterdam] (VU), Centre d'études et de recherche en informatique et communications (CEDRIC), Ecole Nationale Supérieure d'Informatique pour l'Industrie et l'Entreprise (ENSIIE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM), Centre National de Recherche et de Formation sur le Paludisme [Ouagadougou, Burkina Faso] (CNRFP), Centre de Recherche Agronomique de la Savane Humide, Institut Togolais de Recherche Agronomique (ITRA), Institut d'Informatique et de Mathématiques Appliquées de Grenoble (IMAG), Université Joseph Fourier - Grenoble 1 (UJF)-Institut National Polytechnique de Grenoble (INPG)-Centre National de la Recherche Scientifique (CNRS), School of Mechanical, Material and Manufacturing Engineering, University of Nottingham, UK (UON), Department of Geography [Chandigarh], Panjab University [Chandigarh], Faculty of Education and Allied Sciences, M.J.P. Rohilkhand University, Programme franco-indien, Fondation Maison des sciences de l'homme (FMSH), School of Information Technology, Murdoch University, Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Population-Environnement-Développement (LPED), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU), Unité de Recherche sur les Maladies Infectieuses Tropicales Emergentes (URMITE), Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Hewlett-Packard Laboratories [Bristol], Hewlett-Packard, London Knowledge Lab (LKL), Institute of Education - London, National Health Laboratory, Delaunay, Valerie, HESAM Université (HESAM)-HESAM Université (HESAM), INSB-INSB-Centre National de la Recherche Scientifique (CNRS), INSB-INSB-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, Institut Togolais de Recherche Agronomique, and Laboratoire d'Intégration des Systèmes et des Technologies (LIST)
Background: Childhood mortality, particularly in the first 5 years of life, is a major global concern and the target of Millennium Development Goal 4. Although the majority of childhood deaths occur in Africa and Asia, these are also the regions where such deaths are least likely to be registered. The INDEPTH Network works to alleviate this problem by collating detailed individual data from defined Health and Demographic Surveillance sites. By registering deaths and carrying out verbal autopsies to determine cause of death across many such sites, using standardised methods, the Network seeks to generate population-based mortality statistics that are not otherwise available.Objective: To present a description of cause-specific mortality rates and fractions over the first 15 years of life as documented by INDEPTH Network sites in sub-Saharan Africa and south-east Asia.Design: All childhood deaths at INDEPTH sites are routinely registered and followed up with verbal autopsy (VA) interviews. For this study, VA archives were transformed into the WHO 2012 VA standard format and processed using the InterVA-4 model to assign cause of death. Routine surveillance data also provided person-time denominators for mortality rates. Cause-specific mortality rates and cause-specific mortality fractions are presented according to WHO 2012 VA cause groups for neonatal, infant, 1–4 year and 5–14 year age groups.Results: A total of 28,751 childhood deaths were documented during 4,387,824 person-years over 18 sites. Infant mortality ranged from 11 to 78 per 1,000 live births, with under-5 mortality from 15 to 152 per 1,000 live births. Sites in Vietnam and Kenya accounted for the lowest and highest mortality rates reported.Conclusions: Many children continue to die from relatively preventable causes, particularly in areas with high rates of malaria and HIV/AIDS. Neonatal mortality persists at relatively high, and perhaps sometimes under-documented, rates. External causes of death are a significant childhood problem in some settings.Keywords: Childhood; Africa; Asia; mortality; INDEPTH Network; verbal autopsy; InterVA(Published: 29 October 2014)Citation: Glob Health Action 2014, 7: 25363 - http://dx.doi.org/10.3402/gha.v7.25363SPECIAL ISSUE: This paper is part of the Special Issue: INDEPTH Network Cause-Specific Mortality. More papers from this issue can be found at http://www.globalhealthaction.net