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101. The IceCube-Gen2 Collaboration -- Contributions to the 37th International Cosmic Ray Conference (ICRC2021)

Author: Collaboration, IceCube-Gen2, Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Allison, P., Alves Jr., A. A., Amin, N. M., An, R., Andeen, K., Anderson, T., Anton, G., Argüelles, C., Arlen, T. C., Ashida, Y., Axani, S., Bai, X., V., A. Balagopal, Barbano, A., Bartos, I., Barwick, S. W., Bastian, B., Basu, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Bishop, A., Blaufuss, E., Blot, S., Boddenberg, M., Bohmer, M., Bontempo, F., Borowka, J., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Browne, S., Burgman, A., Burley, R. T., Busse, R. S., Campana, M. A., Carnie-Bronca, E. G., Cataldo, M., Chen, C., Chirkin, D., Choi, K., Clark, B. A., Clark, K., Clark, R., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dappen, C., Dave, P., Deaconu, C., De Clercq, C., De Kockere, S., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evans, J. J., Evenson, P. A., Fan, K. L., Farrag, K., Fazely, A. R., Fiedlschuster, S., Fienberg, A. T., Filimonov, K., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gartner, A., Gerhardt, L., Gernhaeuser, R., Ghadimi, A., Giri, P., Glaser, C., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griswold, S., Gündüz, M., Günther, C., Haack, C., Hallgren, A., Halliday, R., Hallmann, S., Halve, L., Halzen, F., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Haugen, J., Haungs, A., Hauser, S., Hebecker, D., Heinen, D., Helbing, K., Hendricks, B., Henningsen, F., Hettinger, E. C., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, B., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Holzapfel, K., Hoshina, K., Huang, F., Huber, M., Huber, T., Huege, T., Hughes, K., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Kalekin, O., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katori, T., Katz, U., Kauer, M., Keivani, A., Kellermann, M., Kelley, J. L., Kheirandish, A., Kin, K., Kintscher, T., Kiryluk, J., Klein, S. R., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Krauss, C. B., Kravchenko, I., Krebs, R., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., Leonard, K., Leszczyńska, A., Li, Y., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., LoSecco, J., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Mandalia, S., Mariş, I. C., Marka, S., Marka, Z., Maruyama, R., Mase, K., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Medina, A., Meier, M., Meighen-Berger, S., Meyers, Z., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Naab, R., Nagai, R., Naumann, U., Necker, J., Nelles, A., Nguyên, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Oberla, E., Pollmann, A. Obertacke, Oehler, M., Oeyen, B., Olivas, A., Omeliukh, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Papp, L., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peters, L., Petersen, T. C., Peterson, J., Philippen, S., Pieloth, D., Pieper, S., Pinfold, J. L., Pittermann, M., Pizzuto, A., Plaisier, I., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Pries, B., Przybylski, G. T., Pyras, L., Raab, C., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rehman, A., Reichherzer, P., Reimann, R., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Riegel, M., Roberts, E. J., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Saffer, J., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Sandstrom, P., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schindler, S., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Shaevitz, M. H., Sharma, A., Shefali, S., Silva, M., Skrzypek, B., Smith, D., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Söldner-Rembold, S., Southall, D., Spannfellner, C., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Taketa, A., Tanaka, H. K. M., Tenholt, F., Ter-Antonyan, S., Tilav, S., Tischbein, F., Tollefson, K., Tomankova, L., Tönnis, C., Torres, J., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Veberic, D., Verpoest, S., Vieregg, A., Vraeghe, M., Walck, C., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weinstock, L., Weiss, M. J., Weldert, J., Welling, C., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Williams, D. R., Wissel, S., Wolf, M., Woschnagg, K., Wrede, G., Wren, S., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yoshida, S., Yu, S., Yuan, T., Zhang, Z., and Zierke, S.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: IceCube-Gen2 is a planned extension of the IceCube Neutrino Observatory at the South Pole. The extension is optimized to search for sources of astrophysical neutrinos from TeV to EeV, and will improve the sensitivity of the observatory to neutrino point sources by a factor of five. The science case of IceCube-Gen2 is built on a successful decade of observations with IceCube. This index of contributions to the 37th International Cosmic Ray Conference in Berlin, Germany (12-23 July 2021) describes research and development efforts for IceCube-Gen2. Included are performance studies of next-generation optical sensors that will detect Cherenkov radiation from TeV-PeV cosmic rays and neutrinos; optimizations of the geometries of the surface and in-ice optical arrays; and estimates of the sensitivity of the proposed IceCube-Gen2 radio array to Askaryan emission from PeV-EeV neutrinos. Contributions related to the existing instrument, IceCube, are available in a separate collection., Comment: To access the list of contributions, please follow the "HTML" link. Links to individual contributions will fill in as authors upload their material
Published: 2021

102. Search for High-Energy Neutrinos from Ultra-Luminous Infrared Galaxies with IceCube

Author: IceCube Collaboration, Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Alves Jr., A. A., Amin, N. M., An, R., Andeen, K., Anderson, T., Anton, G., Argüelles, C., Ashida, Y., Axani, S., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Boddenberg, M., Bontempo, F., Borowka, J., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Browne, S., Burgman, A., Burley, R. T., Busse, R. S., Campana, M. A., Carnie-Bronca, E. G., Chen, C., Chirkin, D., Choi, K., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dappen, C., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fazely, A. R., Fiedlschuster, S., Fienberg, A. T., Filimonov, K., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griswold, S., Gündüz, M., Günther, C., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Haungs, A., Hauser, S., Hebecker, D., Helbing, K., Henningsen, F., Hettinger, E. C., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kin, K., Kintscher, T., Kiryluk, J., Klein, S. R., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., Leonard, K., Leszczyńska, A., Li, Y., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Mari{ş}, I. C., Maruyama, R., Mase, K., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Medina, A., Meier, M., Meighen-Berger, S., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Naab, R., Nagai, R., Naumann, U., Necker, J., Nguy{\~{ê}}n, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peters, L., Peterson, J., Philippen, S., Pieloth, D., Pieper, S., Pittermann, M., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Pries, B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rehman, A., Reichherzer, P., Reimann, R., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Saffer, J., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schindler, S., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Spannfellner, C., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Tilav, S., Tischbein, F., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Williams, D. R., Wolf, M., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yoshida, S., Yu, S., Yuan, T., and Zhang, Z.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: Ultra-luminous infrared galaxies (ULIRGs) have infrared luminosities $L_{\mathrm{IR}} \geq 10^{12} L_{\odot}$, making them the most luminous objects in the infrared sky. These dusty objects are generally powered by starbursts with star-formation rates that exceed $100~ M_{\odot}~ \mathrm{yr}^{-1}$, possibly combined with a contribution from an active galactic nucleus. Such environments make ULIRGs plausible sources of astrophysical high-energy neutrinos, which can be observed by the IceCube Neutrino Observatory at the South Pole. We present a stacking search for high-energy neutrinos from a representative sample of 75 ULIRGs with redshift $z \leq 0.13$ using 7.5 years of IceCube data. The results are consistent with a background-only observation, yielding upper limits on the neutrino flux from these 75 ULIRGs. For an unbroken $E^{-2.5}$ power-law spectrum, we report an upper limit on the stacked flux $\Phi_{\nu_\mu + \bar{\nu}_\mu}^{90\%} = 3.24 \times 10^{-14}~ \mathrm{TeV^{-1}~ cm^{-2}~ s^{-1}}~ (E/10~ \mathrm{TeV})^{-2.5}$ at 90% confidence level. In addition, we constrain the contribution of the ULIRG source population to the observed diffuse astrophysical neutrino flux as well as model predictions., Comment: Accepted for publication in ApJ. 18 pages, 5 figures, 3 tables
Published: 2021
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103. 'Heavy Metal': Management of lead toxicity following a gunshot injury with retained lead fragments, a case report

Author: Ilaria Costantini, Massimo Carollo, Lorenzo Losso, Elia Morando, Matilde Bacchion, Giovanni Mantelli, Mauro Pizzuto, Letizia Spagnuolo, Maria Vittoria Ventura, and Giorgio Ricci
Subjects: Lead poisoning, Toxicology, Poisons, Poison control centers, Chelation therapy, Toxicology. Poisons, RA1190-1270
Abstract: There is limited literature on managing chronic lead exposure from non-removable sources such as lead fragments. In this case report, we present the complexities and clinical considerations involved in treating an elderly patient who sustained a comminuted knee fracture due to a gunshot wound, complicated by retained lead fragments. This case highlights the absence of comprehensive guidelines for managing chronic lead exposure when complete fragment removal is impractical. It also emphasizes the importance of a multidisciplinary approach to decision-making, while considering patient autonomy in such unique clinical scenarios.
Published: 2023
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104. Laurel but Hardy: unintended poisoning, a case report of oleander misidentification as bay laurel

Author: Giovanni Mantelli, Massimo Carollo, Lorenzo Losso, Ilaria Costantini, Elia Morando, Matilde Bacchion, Mauro Pizzuto, Letizia Spagnuolo, and Giorgio Ricci
Subjects: Nerium oleander, Bay laurel, Intoxication, Cardiac glycosides, Digoxin, Poison Control Centers, Toxicology. Poisons, RA1190-1270
Abstract: Introduction: Nerium oleander is a toxic plant containing cardiac glycosides throughout all its parts, thereby posing severe health risks upon ingestion. The clinical manifestations of oleander poisoning closely resemble those of digoxin toxicity, encompassing a spectrum of gastrointestinal symptoms, neuropsychiatric disorders, and cardiac disturbances. This scientific case report describes a case of accidental intoxication resulting from the consumption of an oleander leaves infusion misidentified as bay laurel leaves. Case report: An 84-year-old patient consumed an oleander leaves infusion, and after four hours experienced gastrointestinal symptoms. He contacted the poison control center (PCC) and was advised to go to the emergency department (ED). Upon arrival, the patient presented stable vital signs without cardiac irregularities. The PCC recommended the administration of activated charcoal, vigilant monitoring, including electrocardiography (ECG). Subsequent ECGs assessments revealed the presence of third-degree atrioventricular block; in consultation with the PCC, digoxin-specific antibodies and external pacing were necessary. The patient was discharged on the eighth day in good hemodynamic condition, and outpatient follow-up visits showed clinical stability. Discussion: This study offers insights for the management of similar cases. The limitations of conventional assays in measuring oleander cardiac glycosides were observed, emphasizing reliance on clinical evaluation. The patient's trajectory, remaining asymptomatic despite severe ECG changes post-ingestion, underscores the importance of prolonged clinical monitoring.
Published: 2023
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105. The Healthcare Discrimination Experience Scale: Assessing a Variable Crucial for Explaining Racial/Ethnic Inequities in Patient Activation and Health

Author: Sanford, Keith and Pizzuto, Alexandra E.
Published: 2023
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106. Public expenditure multipliers and informality

Author: Colombo, Emilio, Furceri, Davide, Pizzuto, Pietro, and Tirelli, Patrizio
Published: 2024
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107. Crenigacestat blocking notch pathway reduces liver fibrosis in the surrounding ecosystem of intrahepatic CCA viaTGF-β inhibition

Author: Mancarella, Serena, Gigante, Isabella, Serino, Grazia, Pizzuto, Elena, Dituri, Francesco, Valentini, Maria F, Wang, Jingxiao, Chen, Xin, Armentano, Raffaele, Calvisi, Diego F, and Giannelli, Gianluigi
Subjects: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Cancer, Digestive Diseases, Rare Diseases, Liver Cancer, Liver Disease, Humans, Transforming Growth Factor beta1, Ecosystem, Cholangiocarcinoma, Liver, Bile Duct Neoplasms, Bile Ducts, Intrahepatic, Fibrosis, Tumor Microenvironment, Tissue microenvironment, Liver fibrosis, Tumor stroma crosstalk, Crenigacestat, Smad2, Oncology and carcinogenesis
Abstract: BackgroundIntrahepatic cholangiocarcinoma (iCCA) is a highly malignant tumor characterized by an intensive desmoplastic reaction due to the exaggerated presence of the extracellular (ECM) matrix components. Liver fibroblasts close to the tumor, activated by transforming growth factor (TGF)-β1 and expressing high levels of α-smooth muscle actin (α-SMA), become cancer-associated fibroblasts (CAFs). CAFs are deputed to produce and secrete ECM components and crosstalk with cancer cells favoring tumor progression and resistance to therapy. Overexpression of Notch signaling is implicated in CCA development and growth. The study aimed to determine the effectiveness of the Notch inhibitor, Crenigacestat, on the surrounding microenvironment of iCCA.MethodsWe investigated Crenigacestat's effectiveness in a PDX model of iCCA and human primary culture of CAFs isolated from patients with iCCA.ResultsIn silico analysis of transcriptomic profiling from PDX iCCA tissues treated with Crenigacestat highlighted "liver fibrosis" as one of the most modulated pathways. In the iCCA PDX model, Crenigacestat treatment significantly (p
Published: 2022

108. All-flavor constraints on nonstandard neutrino interactions and generalized matter potential with three years of IceCube DeepCore data

Author: IceCube Collaboration, Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Alves Jr., A. A., Amin, N. M., An, R., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Ashida, Y., Axani, S., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Borowka, J., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Browne, S., Burgman, A., Busse, R. S., Campana, M. A., Chen, C., Chirkin, D., Choi, K., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fazely, A. R., Fiedlschuster, S., Fienberg, A. T., Filimonov, K., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griswold, S., Gündüz, M., Günther, C., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Haungs, A., Hauser, S., Hebecker, D., Helbing, K., Henningsen, F., Hettinger, E. C., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Joppe, R., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kin, K., Kintscher, T., Kiryluk, J., Klein, S. R., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kurahashi, N., Kyriacou, A., Lad, N., Gualda, C. Lagunas, Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., Leonard, K., Leszczyńska, A., Li, Y., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Mariş, I. C., Maruyama, R., Mase, K., McElroy, T., McNally, F., Meagher, K., Medina, A., Meier, M., Meighen-Berger, S., Merz, J., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Naab, R., Nagai, R., Naumann, U., Necker, J., Nguyên, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pittermann, M., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Pries, B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Saffer, J., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Spannfellner, C., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Terliuk, A., Tilav, S., Tischbein, F., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whelan, B. J., Whitehorn, N., Wiebusch, C. H., Williams, D. R., Wolf, M., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yoshida, S., Yu, S., Yuan, T., and Zhang, Z.
Subjects: High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract: We report constraints on nonstandard neutrino interactions (NSI) from the observation of atmospheric neutrinos with IceCube, limiting all individual coupling strengths from a single dataset. Furthermore, IceCube is the first experiment to constrain flavor-violating and nonuniversal couplings simultaneously. Hypothetical NSI are generically expected to arise due to the exchange of a new heavy mediator particle. Neutrinos propagating in matter scatter off fermions in the forward direction with negligible momentum transfer. Hence the study of the matter effect on neutrinos propagating in the Earth is sensitive to NSI independently of the energy scale of new physics. We present constraints on NSI obtained with an all-flavor event sample of atmospheric neutrinos based on three years of IceCube DeepCore data. The analysis uses neutrinos arriving from all directions, with reconstructed energies between 5.6 GeV and 100 GeV. We report constraints on the individual NSI coupling strengths considered singly, allowing for complex phases in the case of flavor-violating couplings. This demonstrates that IceCube is sensitive to the full NSI flavor structure at a level competitive with limits from the global analysis of all other experiments. In addition, we investigate a generalized matter potential, whose overall scale and flavor structure are also constrained., Comment: 22 pages, 12 figures. This submission matches the published version
Published: 2021
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109. Probing neutrino emission at GeV energies from compact binary mergers with the IceCube Neutrino Observatory

Author: Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Alves Jr., A. A., Amin, N. M., An, R., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Ashida, Y., Axani, S., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Borowka, J., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Browne, S., Burgman, A., Busse, R. S., Campana, M. A., Chen, C., Chirkin, D., Choi, K., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fazely, A. R., Fiedlschuster, S., Fienberg, A. T., Filimonov, K., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griswold, S., Gündüz, M., Günther, C., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Haungs, A., Hauser, S., Hebecker, D., Helbing, K., Henningsen, F., Hettinger, E. C., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Joppe, R., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kin, K., Kintscher, T., Kiryluk, J., Klein, S. R., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kurahashi, N., Kyriacou, A., Lad, N., Gualda, C. Lagunas, Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., Leonard, K., Leszczyńska, A., Li, Y., Liu, Q. R., Liubarska, M., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Mari{ş}, I. C., Maruyama, R., Mase, K., McElroy, T., McNally, F., Meagher, K., Medina, A., Meier, M., Meighen-Berger, S., Merz, J., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Naab, R., Nagai, R., Naumann, U., Necker, J., Nguy{\~{ê}}n, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pittermann, M., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Pries, B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Saffer, J., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Spannfellner, C., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Tilav, S., Tischbein, F., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whelan, B. J., Whitehorn, N., Wiebusch, C. H., Williams, D. R., Wolf, M., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yoshida, S., Yu, S., Yuan, T., and Zhang, Z.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: The advent of multi-messenger astronomy has allowed for new types of source searches by neutrino detectors. We present the results of the first search for 0.5 - 5 GeV astrophysical neutrinos emitted from all compact binary mergers, i.e., binary black hole, neutron star black, mass gap and binary neutron star mergers, detected by the LIGO and Virgo interferometers during their three first runs of observation. We use an innovative approach that lowers the energy threshold from ~10 GeV to ~0.5 GeV and searches for an excess of GeV-scale events during astrophysical transient events. No significant excess was found from the studied mergers, and there is currently no hint of a population of GeV neutrino emitters found in the IceCube data., Comment: 22 pages, 3 figures, 1 table
Published: 2021

110. A muon-track reconstruction exploiting stochastic losses for large-scale Cherenkov detectors

Author: Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Alves Jr., A. A., Amin, N. M., An, R., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Axani, S., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Borowka, J., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Browne, S., Burgman, A., Busse, R. S., Campana, M. A., Chen, C., Chirkin, D., Choi, K., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fahey, S., Fazely, A. R., Fiedlschuster, S., Fienberg, A. T., Filimonov, K., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Gündüz, M., Günther, C., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Haungs, A., Hauser, S., Hebecker, D., Helbing, K., Henningsen, F., Hettinger, E. C., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Joppe, R., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kin, K., Kintscher, T., Kiryluk, J., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Krings, K., Kurahashi, N., Kyriacou, A., Gualda, C. Lagunas, Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., Leonard, K., Leszczyńska, A., Li, Y., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Mari{ş}, I. C., Maruyama, R., Mase, K., McNally, F., Meagher, K., Medina, A., Meier, M., Meighen-Berger, S., Merz, J., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Naab, R., Nagai, R., Naumann, U., Necker, J., Nguy{\~{ê}}n, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Pries, B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Saffer, J., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Tilav, S., Tischbein, F., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Valtonen-Mattila, N., Vandenbroucke, J., van Eijk, D., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whelan, B. J., Whitehorn, N., Wiebusch, C. H., Williams, D. R., Wolf, M., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yoshida, S., Yuan, T., and Zhang, Z.
Subjects: High Energy Physics - Experiment, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: IceCube is a cubic-kilometer Cherenkov telescope operating at the South Pole. The main goal of IceCube is the detection of astrophysical neutrinos and the identification of their sources. High-energy muon neutrinos are observed via the secondary muons produced in charge current interactions with nuclei in the ice. Currently, the best performing muon track directional reconstruction is based on a maximum likelihood method using the arrival time distribution of Cherenkov photons registered by the experiment's photomultipliers. A known systematic shortcoming of the prevailing method is to assume a continuous energy loss along the muon track. However at energies $>1$ TeV the light yield from muons is dominated by stochastic showers. This paper discusses a generalized ansatz where the expected arrival time distribution is parametrized by a stochastic muon energy loss pattern. This more realistic parametrization of the loss profile leads to an improvement of the muon angular resolution of up to $20\%$ for through-going tracks and up to a factor 2 for starting tracks over existing algorithms. Additionally, the procedure to estimate the directional reconstruction uncertainty has been improved to be more robust against numerical errors.
Published: 2021
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111. A Convolutional Neural Network based Cascade Reconstruction for the IceCube Neutrino Observatory

Author: Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Alves Jr., A. A., Amin, N. M., An, R., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Axani, S., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Busse, R. S., Campana, M. A., Chen, C., Chirkin, D., Choi, S., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Evans, J., Evenson, P. A., Fahey, S., Fazely, A. R., Fiedlschuster, S., Fienberg, A. T., Filimonov, K., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Haungs, A., Hauser, S., Hebecker, D., Helbing, K., Henningsen, F., Hettinger, E. C., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Joppe, R., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kim, J., Kin, K., Kintscher, T., Kiryluk, J., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Krings, K., Krückl, G., Kurahashi, N., Kyriacou, A., Gualda, C. Lagunas, Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Li, Y., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mallik, P., Mancina, S., Mari{ş}, I. C., Maruyama, R., Mase, K., McNally, F., Meagher, K., Medina, A., Meier, M., Meighen-Berger, S., Merz, J., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morik, K., Morse, R., Moulai, M., Naab, R., Nagai, R., Naumann, U., Necker, J., Nguy{\~{ê}}n, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Pries, B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Renschler, M., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Tilav, S., Tischbein, F., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Valtonen-Mattila, N., Vandenbroucke, J., van Eijk, D., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Williams, D. R., Wolf, M., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yoshida, S., Yuan, T., and Zhang, Z.
Subjects: High Energy Physics - Experiment, Computer Science - Machine Learning
Abstract: Continued improvements on existing reconstruction methods are vital to the success of high-energy physics experiments, such as the IceCube Neutrino Observatory. In IceCube, further challenges arise as the detector is situated at the geographic South Pole where computational resources are limited. However, to perform real-time analyses and to issue alerts to telescopes around the world, powerful and fast reconstruction methods are desired. Deep neural networks can be extremely powerful, and their usage is computationally inexpensive once the networks are trained. These characteristics make a deep learning-based approach an excellent candidate for the application in IceCube. A reconstruction method based on convolutional architectures and hexagonally shaped kernels is presented. The presented method is robust towards systematic uncertainties in the simulation and has been tested on experimental data. In comparison to standard reconstruction methods in IceCube, it can improve upon the reconstruction accuracy, while reducing the time necessary to run the reconstruction by two to three orders of magnitude., Comment: 39 pages, 15 figures, submitted to Journal of Instrumentation; added references
Published: 2021
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112. IceCube Data for Neutrino Point-Source Searches Years 2008-2018

Author: IceCube Collaboration, Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Amin, N. M., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Axani, S., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bohm, C., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Buscher, J., Busse, R. S., Campana, M. A., Carver, T., Chen, C., Cheung, E., Chirkin, D., Choi, S., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Evenson, P. A., Fahey, S., Fazely, A. R., Felde, J., Fienberg, A. T., Filimonov, K., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Ghadimi, A., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Minh, M. Ha, Hanson, K., Hardin, J., Haungs, A., Hauser, S., Hebecker, D., Heix, P., Helbing, K., Hellauer, R., Henningsen, F., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Jonske, F., Joppe, R., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kim, J., Kin, K., Kintscher, T., Kiryluk, J., Kittler, T., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Krings, K., Krückl, G., Kulacz, N., Kurahashi, N., Kyriacou, A., Gualda, C. Lagunas, Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Li, Y., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Lünemann, J., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Maggi, G., Mahn, K. B. M., Makino, Y., Mallik, P., Mancina, S., Mariş, I. C., Maruyama, R., Mase, K., Maunu, R., McNally, F., Meagher, K., Medina, A., Meier, M., Meighen-Berger, S., Merz, J., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Muth, P., Naab, R., Nagai, R., Naumann, U., Necker, J., Neer, G., Nguyên, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Renschler, M., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Shefali, S., Silva, M., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Song, M., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Strotjohann, N. L., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Tilav, S., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Unger, E., Elorrieta, M. A. Unland, Vandenbroucke, J., van Eijk, D., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Williams, D. R., Wolf, M., Wood, T. R., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yoshida, S., Yuan, T., Zhang, Z., and Zöcklein, M.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: IceCube has performed several all-sky searches for point-like neutrino sources using track-like events, including a recent time-integrated analysis using 10 years of IceCube data. This paper accompanies the public data release of these neutrino candidates detected by IceCube between April 6, 2008 and July 8, 2018. The selection includes through-going tracks, primarily due to muon neutrino candidates, that reach the detector from all directions, as well as neutrino track events that start within the instrumented volume. An updated selection and reconstruction for data taken after April 2012 slightly improves the sensitivity of the sample. While more than 80% of the sample overlaps between the old and new versions, differing events can lead to changes relative to the previous 7 year event selection. An a posteriori estimate of the significance of the 2014-2015 TXS flare is reported with an explanation of observed discrepancies with previous results. This public data release, which includes 10 years of data and binned detector response functions for muon neutrino signal events, shows improved sensitivity in generic time-integrated point source analyses and should be preferred over previous releases., Comment: See https://icecube.wisc.edu/science/data/PS-IC40-IC86_VII for the associated data release files. For the associated time-integrated analysis results, see Phys. Rev. Lett. 124, 051103 (2020) (also available at arXiv:1910.08488)
Published: 2021
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113. Search for GeV Neutrino Emission During Intense Gamma-Ray Solar Flares with the IceCube Neutrino Observatory

Author: Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Alves Jr., A. A., Amin, N. M., An, R., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Axani, S., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Borowka, J., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Browne, S., Burgman, A., Busse, R. S., Campana, M. A., Chen, C., Chirkin, D., Choi, S., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fahey, S., Fazely, A. R., Fiedlschuster, S., Fienberg, A. T., Filimonov, K., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Gündüz, M., Günther, C., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Haungs, A., Hauser, S., Hebecker, D., Helbing, K., Henningsen, F., Hettinger, E. C., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Joppe, R., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kim, J., Kin, K., Kintscher, T., Kiryluk, J., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Krings, K., Krückl, G., Kurahashi, N., Kyriacou, A., Gualda, C. Lagunas, Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Li, Y., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Mariş, I. C., Maruyama, R., Mase, K., McNally, F., Meagher, K., Medina, A., Meier, M., Meighen-Berger, S., Merz, J., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Naab, R., Nagai, R., Naumann, U., Necker, J., Nguyen, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Pries, B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Tilav, S., Tischbein, F., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Valtonen-Mattila, N., Vandenbroucke, J., van Eijk, D., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Williams, D. R., Wolf, M., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yoshida, S., Yuan, T., and Zhang, Z.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Solar and Stellar Astrophysics
Abstract: Solar flares convert magnetic energy into thermal and non-thermal plasma energy, the latter implying particle acceleration of charged particles such as protons. Protons are injected out of the coronal acceleration region and can interact with dense plasma in the lower solar atmosphere, producing mesons that subsequently decay into gamma rays and neutrinos at O(MeV-GeV) energies. We present the results of the first search for GeV neutrinos emitted during solar flares carried out with the IceCube Neutrino Observatory. While the experiment was originally designed to detect neutrinos with energies between 10 GeV and a few PeV, a new approach allowing for a O(GeV) energy threshold will be presented. The resulting limits allow us to constrain some of the theoretical estimates of the expected neutrino flux., Comment: 28 pages, 7 figures, 3 tables
Published: 2021
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114. Leveraging Multi-modal Sensing for Robotic Insertion Tasks in R&D Laboratories.

Author: Aaron Butterworth, Gabriella Pizzuto, Leszek Pecyna, Andrew I. Cooper, and Shan Luo 0001
Published: 2023
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115. Regional fiscal spillovers: The role of trade linkages

Author: Bettarelli, Luca, Furceri, Davide, Pizzuto, Pietro, and Yarveisi, Khatereh
Published: 2024
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116. Impact of Gore Cardioform Atrial Septal Defect Occluder on Atrial and Ventricular Electromechanics in a Pediatric Population

Author: Castaldi, Biagio, Santoro, Giuseppe, Di Candia, Angela, Marchese, Pietro, Cantinotti, Massimiliano, Pizzuto, Alessandra, Scalera, Silvia, Garibaldi, Silvia, Fumanelli, Jennifer, Sirico, Domenico, and Di Salvo, Giovanni
Published: 2024
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117. A pan-influenza antibody inhibiting neuraminidase via receptor mimicry

Author: Momont, Corey, Dang, Ha V., Zatta, Fabrizia, Hauser, Kevin, Wang, Caihong, di Iulio, Julia, Minola, Andrea, Czudnochowski, Nadine, De Marco, Anna, Branch, Kaitlin, Donermeyer, David, Vyas, Siddhant, Chen, Alex, Ferri, Elena, Guarino, Barbara, Powell, Abigail E., Spreafico, Roberto, Yim, Samantha S., Balce, Dale R., Bartha, Istvan, Meury, Marcel, Croll, Tristan I., Belnap, David M., Schmid, Michael A., Schaiff, William Timothy, Miller, Jessica L., Cameroni, Elisabetta, Telenti, Amalio, Virgin, Herbert W., Rosen, Laura E., Purcell, Lisa A., Lanzavecchia, Antonio, Snell, Gyorgy, Corti, Davide, and Pizzuto, Matteo Samuele
Published: 2023
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118. Observation of seasonal variations of the flux of high-energy atmospheric neutrinos with IceCube

Author: R. Abbasi, M. Ackermann, J. Adams, S. K. Agarwalla, N. Aggarwal, J. A. Aguilar, M. Ahlers, J. M. Alameddine, N. M. Amin, K. Andeen, G. Anton, C. Argüelles, Y. Ashida, S. Athanasiadou, S. N. Axani, X. Bai, A. Balagopal V., M. Baricevic, S. W. Barwick, V. Basu, R. Bay, J. J. Beatty, K.-H. Becker, J. Becker Tjus, J. Beise, C. Bellenghi, S. BenZvi, D. Berley, E. Bernardini, D. Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, F. Bontempo, J. Y. Book, J. Borowka, C. Boscolo Meneguolo, S. Böser, O. Botner, J. Böttcher, E. Bourbeau, J. Braun, B. Brinson, J. Brostean-Kaiser, R. T. Burley, R. S. Busse, D. Butterfield, M. A. Campana, K. Carloni, E. G. Carnie-Bronca, S. Chattopadhyay, C. Chen, Z. Chen, D. Chirkin, S. Choi, B. A. Clark, L. Classen, A. Coleman, G. H. Collin, A. Connolly, J. M. Conrad, P. Coppin, P. Correa, S. Countryman, D. F. Cowen, C. Dappen, P. Dave, C. De Clercq, J. J. DeLaunay, D. Delgado López, H. Dembinski, S. Deng, K. Deoskar, A. Desai, P. Desiati, K. D. de Vries, G. de Wasseige, T. DeYoung, A. Diaz, J. C. Díaz-Vélez, M. Dittmer, A. Domi, H. Dujmovic, M. A. DuVernois, T. Ehrhardt, P. Eller, R. Engel, H. Erpenbeck, J. Evans, P. A. Evenson, K. L. Fan, K. Fang, A. R. Fazely, A. Fedynitch, N. Feigl, S. Fiedlschuster, C. Finley, L. Fischer, D. Fox, A. Franckowiak, E. Friedman, A. Fritz, P. Fürst, T. K. Gaisser, J. Gallagher, E. Ganster, A. Garcia, S. Garrappa, L. Gerhardt, A. Ghadimi, C. Glaser, T. Glauch, T. Glüsenkamp, N. Goehlke, J. G. Gonzalez, S. Goswami, D. Grant, S. J. Gray, S. Griffin, S. Griswold, C. Günther, P. Gutjahr, C. Haack, A. Hallgren, R. Halliday, L. Halve, F. Halzen, H. Hamdaoui, M. Ha Minh, K. Hanson, J. Hardin, A. A. Harnisch, P. Hatch, A. Haungs, S. Hauser, K. Helbing, J. Hellrung, F. Henningsen, L. Heuermann, S. Hickford, A. Hidvegi, C. Hill, G. C. Hill, K. D. Hoffman, K. Hoshina, W. Hou, T. Huber, K. Hultqvist, M. Hünnefeld, R. Hussain, K. Hymon, S. In, N. Iovine, A. Ishihara, M. Jacquart, M. Jansson, G. S. Japaridze, K. Jayakumar, M. Jeong, M. Jin, B. J. P. Jones, D. Kang, W. Kang, X. Kang, A. Kappes, D. Kappesser, L. Kardum, T. Karg, M. Karl, A. Karle, U. Katz, M. Kauer, J. L. Kelley, A. Khatee Zathul, A. Kheirandish, K. Kin, J. Kiryluk, S. R. Klein, A. Kochocki, R. Koirala, H. Kolanoski, T. Kontrimas, L. Köpke, C. Kopper, D. J. Koskinen, P. Koundal, M. Kovacevich, M. Kowalski, T. Kozynets, K. Kruiswijk, E. Krupczak, A. Kumar, E. Kun, N. Kurahashi, N. Lad, C. Lagunas Gualda, M. Lamoureux, M. J. Larson, F. Lauber, J. P. Lazar, J. W. Lee, K. Leonard DeHolton, A. Leszczyńska, M. Lincetto, Q. R. Liu, M. Liubarska, E. Lohfink, C. Love, C. J. Lozano Mariscal, L. Lu, F. Lucarelli, A. Ludwig, W. Luszczak, Y. Lyu, W. Y. Ma, J. Madsen, K. B. M. Mahn, Y. Makino, S. Mancina, W. Marie Sainte, I. C. Mariş, S. Marka, Z. Marka, M. Marsee, I. Martinez-Soler, R. Maruyama, F. Mayhew, T. McElroy, F. McNally, J. V. Mead, K. Meagher, S. Mechbal, A. Medina, M. Meier, S. Meighen-Berger, Y. Merckx, L. Merten, J. Micallef, D. Mockler, T. Montaruli, R. W. Moore, Y. Morii, R. Morse, M. Moulai, T. Mukherjee, R. Naab, R. Nagai, M. Nakos, U. Naumann, J. Necker, M. Neumann, H. Niederhausen, M. U. Nisa, A. Noell, S. C. Nowicki, A. Obertacke Pollmann, M. Oehler, B. Oeyen, A. Olivas, R. Orsoe, J. Osborn, E. O’Sullivan, H. Pandya, N. Park, G. K. Parker, E. N. Paudel, L. Paul, C. Pérez de los Heros, J. Peterson, S. Philippen, S. Pieper, A. Pizzuto, M. Plum, Y. Popovych, M. Prado Rodriguez, B. Pries, R. Procter-Murphy, G. T. Przybylski, C. Raab, J. Rack-Helleis, K. Rawlins, Z. Rechav, A. Rehman, P. Reichherzer, G. Renzi, E. Resconi, S. Reusch, W. Rhode, M. Richman, B. Riedel, E. J. Roberts, S. Robertson, S. Rodan, G. Roellinghoff, M. Rongen, C. Rott, T. Ruhe, L. Ruohan, D. Ryckbosch, I. Safa, J. Saffer, D. Salazar-Gallegos, P. Sampathkumar, S. E. Sanchez Herrera, A. Sandrock, M. Santander, S. Sarkar, J. Savelberg, P. Savina, M. Schaufel, H. Schieler, S. Schindler, B. Schlüter, T. Schmidt, J. Schneider, F. G. Schröder, L. Schumacher, G. Schwefer, S. Sclafani, D. Seckel, S. Seunarine, A. Sharma, S. Shefali, N. Shimizu, M. Silva, B. Skrzypek, B. Smithers, R. Snihur, J. Soedingrekso, A. Søgaard, D. Soldin, G. Sommani, C. Spannfellner, G. M. Spiczak, C. Spiering, M. Stamatikos, T. Stanev, R. Stein, T. Stezelberger, T. Stürwald, T. Stuttard, G. W. Sullivan, I. Taboada, S. Ter-Antonyan, W. G. Thompson, J. Thwaites, S. Tilav, K. Tollefson, C. Tönnis, S. Toscano, D. Tosi, A. Trettin, C. F. Tung, R. Turcotte, J. P. Twagirayezu, B. Ty, M. A. Unland Elorrieta, A. K. Upadhyay, K. Upshaw, N. Valtonen-Mattila, J. Vandenbroucke, N. van Eijndhoven, D. Vannerom, J. van Santen, J. Vara, J. Veitch-Michaelis, M. Venugopal, S. Verpoest, D. Veske, C. Walck, T. B. Watson, C. Weaver, P. Weigel, A. Weindl, J. Weldert, C. Wendt, J. Werthebach, M. Weyrauch, N. Whitehorn, C. H. Wiebusch, N. Willey, D. R. Williams, M. Wolf, G. Wrede, J. Wulff, X. W. Xu, J. P. Yanez, E. Yildizci, S. Yoshida, F. Yu, S. Yu, T. Yuan, Z. Zhang, P. Zhelnin, and IceCube Collaboration
Subjects: Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract Atmospheric muon neutrinos are produced by meson decays in cosmic-ray-induced air showers. The flux depends on meteorological quantities such as the air temperature, which affects the density of air. Competition between decay and re-interaction of those mesons in the first particle production generations gives rise to a higher neutrino flux when the air density in the stratosphere is lower, corresponding to a higher temperature. A measurement of a temperature dependence of the atmospheric $$\nu _{\mu }$$ ν μ flux provides a novel method for constraining hadronic interaction models of air showers. It is particularly sensitive to the production of kaons. Studying this temperature dependence for the first time requires a large sample of high-energy neutrinos as well as a detailed understanding of atmospheric properties. We report the significant ( $$> 10 \; \sigma $$ > 10 σ ) observation of a correlation between the rate of more than 260,000 neutrinos, detected by IceCube between 2012 and 2018, and atmospheric temperatures of the stratosphere, measured by the Atmospheric Infrared Sounder (AIRS) instrument aboard NASA’s AQUA satellite. For the observed 10 $$\%$$ % seasonal change of effective atmospheric temperature we measure a 3.5(3) $$\%$$ % change in the muon neutrino flux. This observed correlation deviates by about 2-3 standard deviations from the expected correlation of 4.3 $$\%$$ % as obtained from theoretical predictions under the assumption of various hadronic interaction models.
Published: 2023
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119. Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical models

Author: Matteo Centonze, Giusy Di Conza, Michael Lahn, Isabel Fabregat, Francesco Dituri, Isabella Gigante, Grazia Serino, Rosanna Scialpi, Livianna Carrieri, Roberto Negro, Elena Pizzuto, and Gianluigi Giannelli
Subjects: Autotaxin, Lysophosphatidic acid, Gastrointestinal cancers, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: Abstract Background Autotaxin (ATX) is a secreted enzyme that converts lysophosphatidylcholine to lysophosphatidic acid (LPA). LPA stimulates cell proliferation and migration and promotes wound repair following tissue damage. ATX levels are directly correlated with stage and grade in several human cancers. Several small molecule ATX inhibitors have been developed in recent years. IOA-289 is a potent ATX inhibitor, developed to treat cancers containing fibrosis. In this study, we tested IOA-289 treatment on different gastrointestinal tract tumor cell lines, in order to evaluate its effects on viability and motility. Methods To determine the effects on cell viability and proliferation of treatment with increasing concentrations of IOA-289, we used the crystal violet assay, a clonogenic assay in matrigel, and we evaluated the inhibitor’s effect on formation of 3D spheroids in an in vitro model. The effect of IOA-289 on cell cycle phases was analysed with a redox dye reagent. Cell migration capacity was evaluated by wound healing assay and transwell migration assay. To evaluate the pro-apoptotic effect of the inhibitor, cells were stained with Annexin V and immunofluorescence and flow cytometry analysis were performed. An antibody array was also used, to discriminate, in various samples, the differential expression of 43 proteins involved in the apoptosis pathway. Results We found that IOA-289 is able to inhibit both growth and migration of gastrointestinal tract tumor cell lines, both in 2D (crystal violet assay) and 3D in vitro models (spheroid formation and clonogenic assay in matrigel). This effect is dose-dependent, and the drug is most effective when administered in FBS-free culture medium. The inhibitory effect on cell growth is due to a pro-apoptotic effect of IOA-289. Staining with FITC-conjugated Annexin V showed that IOA-289 induced a dose-dependent increase in fluorescence following incubation for 24 h, and apoptotic cells were also distinguished in flow cytometry using Annexin/PI staining. The antibody array shows that treatment with IOA-289 causes the increased expression of several pro-apoptotic proteins in all tested cell lines. Conclusions These results indicate that IOA-289 may be an effective drug for the treatment of tumors of the gastrointestinal tract, particularly those characterized by a high degree of fibrosis.
Published: 2023
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120. Erratum: 'Limits on Neutrino Emission from GRB 221009A from MeV to PeV Using the IceCube Neutrino Observatory' (2023, ApJL, 946, L26)

Author: R. Abbasi, M. Ackermann, J. Adams, S. K. Agarwalla, N. Aggarwal, J. A. Aguilar, M. Ahlers, J. M. Alameddine, N. M. Amin, K. Andeen, G. Anton, C. Argüelles, Y. Ashida, S. Athanasiadou, S. N. Axani, X. Bai, A. Balagopal V., M. Baricevic, S. W. Barwick, V. Basu, R. Bay, J. J. Beatty, K.-H. Becker, J. Becker Tjus, J. Beise, C. Bellenghi, S. BenZvi, D. Berley, E. Bernardini, D. Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, F. Bontempo, J. Y. Book, J. Borowka, C. Boscolo Meneguolo, S. Böser, O. Botner, J. Böttcher, E. Bourbeau, J. Braun, B. Brinson, J. Brostean-Kaiser, R. T. Burley, R. S. Busse, M. A. Campana, K. Carloni, E. G. Carnie-Bronca, C. Chen, Z. Chen, D. Chirkin, S. Choi, B. A. Clark, L. Classen, A. Coleman, G. H. Collin, A. Connolly, J. M. Conrad, P. Coppin, P. Correa, S. Countryman, D. F. Cowen, C. Dappen, P. Dave, C. De Clercq, J. J. DeLaunay, D. Delgado López, H. Dembinski, K. Deoskar, A. Desai, P. Desiati, K. D. de Vries, G. de Wasseige, T. DeYoung, A. Diaz, J. C. Díaz-Vélez, M. Dittmer, A. Domi, H. Dujmovic, M. A. DuVernois, T. Ehrhardt, P. Eller, R. Engel, H. Erpenbeck, J. Evans, P. A. Evenson, K. L. Fan, A. R. Fazely, A. Fedynitch, N. Feigl, S. Fiedlschuster, C. Finley, L. Fischer, D. Fox, A. Franckowiak, E. Friedman, A. Fritz, P. Fürst, T. K. Gaisser, J. Gallagher, E. Ganster, A. Garcia, S. Garrappa, L. Gerhardt, A. Ghadimi, C. Glaser, T. Glauch, T. Glüsenkamp, N. Goehlke, J. G. Gonzalez, S. Goswami, D. Grant, S. J. Gray, S. Griffin, S. Griswold, C. Günther, P. Gutjahr, C. Haack, A. Hallgren, R. Halliday, L. Halve, F. Halzen, H. Hamdaoui, M. Ha Minh, K. Hanson, J. Hardin, A. A. Harnisch, P. Hatch, A. Haungs, K. Helbing, J. Hellrung, F. Henningsen, L. Heuermann, S. Hickford, A. Hidvegi, C. Hill, G. C. Hill, K. D. Hoffman, K. Hoshina, W. Hou, T. Huber, K. Hultqvist, M. Hünnefeld, R. Hussain, K. Hymon, S. In, N. Iovine, A. Ishihara, M. Jansson, G. S. Japaridze, M. Jeong, M. Jin, B. J. P. Jones, D. Kang, W. Kang, X. Kang, A. Kappes, D. Kappesser, L. Kardum, T. Karg, M. Karl, A. Karle, U. Katz, M. Kauer, J. L. Kelley, A. Kheirandish, K. Kin, J. Kiryluk, S. R. Klein, A. Kochocki, R. Koirala, H. Kolanoski, T. Kontrimas, L. Köpke, C. Kopper, D. J. Koskinen, P. Koundal, M. Kovacevich, M. Kowalski, T. Kozynets, K. Kruiswijk, E. Krupczak, A. Kumar, E. Kun, N. Kurahashi, N. Lad, C. Lagunas Gualda, M. Lamoureux, M. J. Larson, F. Lauber, J. P. Lazar, J. W. Lee, K. Leonard DeHolton, A. Leszczyńska, M. Lincetto, Q. R. Liu, M. Liubarska, E. Lohfink, C. Love, C. J. Lozano Mariscal, L. Lu, F. Lucarelli, A. Ludwig, W. Luszczak, Y. Lyu, W. Y. Ma, J. Madsen, K. B. M. Mahn, Y. Makino, S. Mancina, W. Marie Sainte, I. C. Mariş, S. Marka, Z. Marka, M. Marsee, I. Martinez-Soler, R. Maruyama, F. Mayhew, T. McElroy, F. McNally, J. V. Mead, K. Meagher, S. Mechbal, A. Medina, M. Meier, S. Meighen-Berger, Y. Merckx, L. Merten, J. Micallef, D. Mockler, T. Montaruli, R. W. Moore, Y. Morii, R. Morse, M. Moulai, T. Mukherjee, R. Naab, R. Nagai, U. Naumann, J. Necker, M. Neumann, H. Niederhausen, M. U. Nisa, A. Noell, S. C. Nowicki, A. Obertacke Pollmann, M. Oehler, B. Oeyen, A. Olivas, R. Orsoe, J. Osborn, E. O’Sullivan, H. Pandya, N. Park, G. K. Parker, E. N. Paudel, L. Paul, C. Pérez de los Heros, J. Peterson, S. Philippen, S. Pieper, A. Pizzuto, M. Plum, Y. Popovych, M. Prado Rodriguez, B. Pries, R. Procter-Murphy, G. T. Przybylski, C. Raab, J. Rack-Helleis, K. Rawlins, Z. Rechav, A. Rehman, P. Reichherzer, G. Renzi, E. Resconi, S. Reusch, W. Rhode, M. Richman, B. Riedel, E. J. Roberts, S. Robertson, S. Rodan, G. Roellinghoff, M. Rongen, C. Rott, T. Ruhe, L. Ruohan, D. Ryckbosch, I. Safa, J. Saffer, D. Salazar-Gallegos, P. Sampathkumar, S. E. Sanchez Herrera, A. Sandrock, M. Santander, S. Sarkar, J. Savelberg, P. Savina, M. Schaufel, H. Schieler, S. Schindler, B. Schlüter, T. Schmidt, J. Schneider, F. G. Schröder, L. Schumacher, G. Schwefer, S. Sclafani, D. Seckel, S. Seunarine, A. Sharma, S. Shefali, N. Shimizu, M. Silva, B. Skrzypek, B. Smithers, R. Snihur, J. Soedingrekso, A. Søgaard, D. Soldin, G. Sommani, C. Spannfellner, G. M. Spiczak, C. Spiering, M. Stamatikos, T. Stanev, R. Stein, T. Stezelberger, T. Stürwald, T. Stuttard, G. W. Sullivan, I. Taboada, S. Ter-Antonyan, W. G. Thompson, J. Thwaites, S. Tilav, K. Tollefson, C. Tönnis, S. Toscano, D. Tosi, A. Trettin, C. F. Tung, R. Turcotte, J. P. Twagirayezu, B. Ty, M. A. Unland Elorrieta, K. Upshaw, N. Valtonen-Mattila, J. Vandenbroucke, N. van Eijndhoven, D. Vannerom, J. van Santen, J. Vara, J. Veitch-Michaelis, M. Venugopal, S. Verpoest, D. Veske, C. Walck, T. B. Watson, C. Weaver, P. Weigel, A. Weindl, J. Weldert, C. Wendt, J. Werthebach, M. Weyrauch, N. Whitehorn, C. H. Wiebusch, N. Willey, D. R. Williams, M. Wolf, G. Wrede, J. Wulff, X. W. Xu, J. P. Yanez, E. Yildizci, S. Yoshida, F. Yu, S. Yu, T. Yuan, Z. Zhang, P. Zhelnin, and IceCube Collaboration
Subjects: Astrophysics, QB460-466
Published: 2024
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121. LeptonInjector and LeptonWeighter: A neutrino event generator and weighter for neutrino observatories

Author: Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Alves Jr., A. A., Amin, N. M., An, R., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Axani, S., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Busse, R. S., Campana, M. A., Chen, C., Chirkin, D., Choi, S., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Evans, J., Evenson, P. A., Fahey, S., Fazely, A. R., Fiedlschuster, S., Fienberg, A. T., Filimonov, K., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Haungs, A., Hauser, S., Hebecker, D., Helbing, K., Henningsen, F., Hettinger, E. C., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Joppe, R., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kim, J., Kin, K., Kintscher, T., Kiryluk, J., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Krings, K., Krückl, G., Kurahashi, N., Kyriacou, A., Gualda, C. Lagunas, Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Li, Y., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mallik, P., Mancina, S., Mariş, I. C., Maruyama, R., Mase, K., McNally, F., Meagher, K., Medina, A., Meier, M., Meighen-Berger, S., Merz, J., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Naab, R., Nagai, R., Naumann, U., Necker, J., Nguyen, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Pries, B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Renschler, M., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Tilav, S., Tischbein, F., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Valtonen-Mattila, N., Vandenbroucke, J., van Eijk, D., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Williams, D. R., Wolf, M., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yoshida, S., Yuan, T., and Zhang, Z.
Subjects: Physics - Computational Physics, High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract: We present a high-energy neutrino event generator, called LeptonInjector, alongside an event weighter, called LeptonWeighter. Both are designed for large-volume Cherenkov neutrino telescopes such as IceCube. The neutrino event generator allows for quick and flexible simulation of neutrino events within and around the detector volume, and implements the leading Standard Model neutrino interaction processes relevant for neutrino observatories: neutrino-nucleon deep-inelastic scattering and neutrino-electron annihilation. In this paper, we discuss the event generation algorithm, the weighting algorithm, and the main functions of the publicly available code, with examples., Comment: 28 pages, 10 figures, 3 tables
Published: 2020
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122. Follow-up of astrophysical transients in real time with the IceCube Neutrino Observatory

Author: Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Alves Jr., A. A., Amin, N. M., An, R., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Axani, S., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Busse, R. S., Campana, M. A., Chen, C., Chirkin, D., Choi, S., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Evans, J., Evenson, P. A., Fahey, S., Fazely, A. R., Fiedlschuster, S., Fienberg, A. T., Filimonov, K., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Haungs, A., Hauser, S., Hebecker, D., Helbing, K., Henningsen, F., Hettinger, E. C., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Joppe, R., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kim, J., Kin, K., Kintscher, T., Kiryluk, J., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Krings, K., Krückl, G., Kurahashi, N., Kyriacou, A., Gualda, C. Lagunas, Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Li, Y., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mallik, P., Mancina, S., Mariş, I. C., Maruyama, R., Mase, K., McNally, F., Meagher, K., Medina, A., Meier, M., Meighen-Berger, S., Merz, J., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Naab, R., Nagai, R., Naumann, U., Necker, J., Nguyên, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Pries, B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Renschler, M., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Shefali, S., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Tilav, S., Tischbein, F., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Vandenbroucke, J., van Eijk, D., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Williams, D. R., Wolf, M., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yoshida, S., Yuan, T., and Zhang, Z.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: In multi-messenger astronomy, rapid investigation of interesting transients is imperative. As an observatory with a 4$\pi$ steradian field of view and $\sim$99\% uptime, the IceCube Neutrino Observatory is a unique facility to follow up transients, and to provide valuable insight for other observatories and inform their observing decisions. Since 2016, IceCube has been using low-latency data to rapidly respond to interesting astrophysical events reported by the multi-messenger observational community. Here, we describe the pipeline used to perform these follow up analyses and provide a summary of the 58 analyses performed as of July 2020. We find no significant signal in the first 58 analyses performed. The pipeline has helped inform various electromagnetic observing strategies, and has constrained neutrino emission from potential hadronic cosmic accelerators., Comment: 18 pages, 9 figures
Published: 2020
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123. A search for time-dependent astrophysical neutrino emission with IceCube data from 2012 to 2017

Author: IceCube Collaboration, Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Alves Jr., A. A., Amin, N. M., An, R., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Axani, S., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Busse, R. S., Campana, M. A., Chen, C., Chirkin, D., Choi, S., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Evans, J., Evenson, P. A., Fahey, S., Fazely, A. R., Fiedlschuster, S., Fienberg, A. T., Filimonov, K., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Haungs, A., Hauser, S., Hebecker, D., Helbing, K., Henningsen, F., Hettinger, E. C., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Joppe, R., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kim, J., Kin, K., Kintscher, T., Kiryluk, J., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Krings, K., Krückl, G., Kurahashi, N., Kyriacou, A., Gualda, C. Lagunas, Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Li, Y., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mallik, P., Mancina, S., Mariş, I. C., Maruyama, R., Mase, K., McNally, F., Meagher, K., Medina, A., Meier, M., Meighen-Berger, S., Merz, J., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Naab, R., Nagai, R., Naumann, U., Necker, J., Nguyên, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Pries, B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Renschler, M., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Shefali, S., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Tilav, S., Tischbein, F., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Vandenbroucke, J., van Eijk, D., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Williams, D. R., Wolf, M., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yoshida, S., Yuan, T., and Zhang, Z.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: High-energy neutrinos are unique messengers of the high-energy universe, tracing the processes of cosmic-ray acceleration. This paper presents analyses focusing on time-dependent neutrino point-source searches. A scan of the whole sky, making no prior assumption about source candidates, is performed, looking for a space and time clustering of high-energy neutrinos in data collected by the IceCube Neutrino Observatory between 2012 and 2017. No statistically significant evidence for a time-dependent neutrino signal is found with this search during this period since all results are consistent with the background expectation. Within this study period, the blazar 3C 279, showed strong variability, inducing a very prominent gamma-ray flare observed in 2015 June. This event motivated a dedicated study of the blazar, which consists of searching for a time-dependent neutrino signal correlated with the gamma-ray emission. No evidence for a time-dependent signal is found. Hence, an upper limit on the neutrino fluence is derived, allowing us to constrain a hadronic emission model.
Published: 2020
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124. First all-flavor search for transient neutrino emission using 3-years of IceCube DeepCore data

Author: Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Alves Jr., A. A., Amin, N. M., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Axani, S., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Busse, R. S., Campana, M. A., Chen, C., Chirkin, D., Choi, S., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Evans, J., Evenson, P. A., Fahey, S., Fazely, A. R., Fiedlschuster, S., Fienberg, A. T., Filimonov, K., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Ghadimi, A., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Minh, M. Ha, Hanson, K., Hardin, J., Haungs, A., Hauser, S., Hebecker, D., Helbing, K., Henningsen, F., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Joppe, R., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kim, J., Kin, K., Kintscher, T., Kiryluk, J., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Krings, K., Krückl, G., Kurahashi, N., Kyriacou, A., Gualda, C. Lagunas, Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Li, Y., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mallik, P., Mancina, S., Mariş, I. C., Maruyama, R., Mase, K., McNally, F., Meagher, K., Medici, M., Medina, A., Meier, M., Meighen-Berger, S., Merz, J., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Naab, R., Nagai, R., Naumann, U., Necker, J., Neer, G., Nguyên, L. V., Nielsen, M. L., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Renschler, M., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Shefali, S., Silva, M., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Strotjohann, N. L., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Tilav, S., Tischbein, F., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Unger, E., Elorrieta, M. A. Unland, Vandenbroucke, J., van Eijk, D., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Williams, D. R., Wolf, M., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yoshida, S., Yuan, T., and Zhang, Z.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: Since the discovery of a flux of high-energy astrophysical neutrinos, searches for their origins have focused primarily at TeV-PeV energies. Compared to sub-TeV searches, high-energy searches benefit from an increase in the neutrino cross section, improved angular resolution on the neutrino direction, and a reduced background from atmospheric neutrinos and muons. However, the focus on high energy does not preclude the existence of sub-TeV neutrino emission where IceCube retains sensitivity. Here we present the first all-flavor search from IceCube for transient emission of low-energy neutrinos, focusing on the energy region of 5.6-100 GeV using three years of data obtained with the IceCube-DeepCore detector. We find no evidence of transient neutrino emission in the data, thus leading to a constraint on the volumetric rate of astrophysical transient sources in the range of $\sim 705-2301\, \text{Gpc}^{-3}\, \text{yr}^{-1}$ for sources following a subphotospheric energy spectrum with a mean energy of 100 GeV and a bolometric energy of $10^{52}$ erg., Comment: 16 pages, 10 figures. Update from previous arXiv version reflects a change to the title, minor text edits, and additional description of the statistical derivation of the results, which were all part of the JCAP review process
Published: 2020
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125. Detection of astrophysical tau neutrino candidates in IceCube

Author: Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Alves Jr., A. A., Amin, N. M., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Axani, S., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Busse, R. S., Campana, M. A., Chen, C., Chirkin, D., Choi, S., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Evans, J., Evenson, P. A., Fahey, S., Fazely, A. R., Fiedlschuster, S., Fienberg, A. T., Filimonov, K., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Ghadimi, A., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Minh, M. Ha, Hanson, K., Hardin, J., Haungs, A., Hauser, S., Hebecker, D., Helbing, K., Henningsen, F., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Joppe, R., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kim, J., Kin, K., Kintscher, T., Kiryluk, J., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Krings, K., Krückl, G., Kulacz, N., Kurahashi, N., Kyriacou, A., Gualda, C. Lagunas, Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Li, Y., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mallik, P., Mancina, S., Mariş, I. C., Maruyama, R., Mase, K., McNally, F., Meagher, K., Medina, A., Meier, M., Meighen-Berger, S., Merz, J., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Naab, R., Nagai, R., Naumann, U., Necker, J., Neer, G., Nguyen, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Renschler, M., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Shefali, S., Silva, M., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Strotjohann, N. L., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Tilav, S., Tischbein, F., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Unger, E., Elorrieta, M. A. Unland, Usner, M., Vandenbroucke, J., van Eijk, D., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Wandkowsky, N., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Williams, D. R., Wolf, M., Wood, T. R., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yoshida, S., Yuan, T., and Zhang, Z.
Subjects: High Energy Physics - Experiment, Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Phenomenology
Abstract: High-energy tau neutrinos are rarely produced in atmospheric cosmic-ray showers or at cosmic particle accelerators, but are expected to emerge during neutrino propagation over cosmic distances due to flavor mixing. When high energy tau neutrinos interact inside the IceCube detector, two spatially separated energy depositions may be resolved, the first from the charged current interaction and the second from the tau lepton decay. We report a novel analysis of 7.5 years of IceCube data that identifies two candidate tau neutrinos among the 60 ``High-Energy Starting Events'' (HESE) collected during that period. The HESE sample offers high purity, all-sky sensitivity, and distinct observational signatures for each neutrino flavor, enabling a new measurement of the flavor composition. The measured astrophysical neutrino flavor composition is consistent with expectations, and an astrophysical tau neutrino flux is indicated at 2.8$\sigma$ significance., Comment: This article is supported by a long-form paper that discusses the high-energy starting event selection titled: "The IceCube high-energy starting event sample: Description and flux characterization with 7.5 years of data."
Published: 2020
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126. Measurement of the high-energy all-flavor neutrino-nucleon cross section with IceCube

Author: Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Alves Jr., A. A., Amin, N. M., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Axani, S., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Busse, R. S., Campana, M. A., Chen, C., Chirkin, D., Choi, S., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Evans, J., Evenson, P. A., Fahey, S., Fazely, A. R., Fiedlschuster, S., Fienberg, A. T., Filimonov, K., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Ghadimi, A., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Minh, M. Ha, Hanson, K., Hardin, J., Haungs, A., Hauser, S., Hebecker, D., Helbing, K., Henningsen, F., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Joppe, R., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kim, J., Kin, K., Kintscher, T., Kiryluk, J., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Krings, K., Krückl, G., Kulacz, N., Kurahashi, N., Kyriacou, A., Gualda, C. Lagunas, Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Li, Y., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mallik, P., Mancina, S., Mariş, I. C., Maruyama, R., Mase, K., McNally, F., Meagher, K., Medina, A., Meier, M., Meighen-Berger, S., Merz, J., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Naab, R., Nagai, R., Naumann, U., Necker, J., Neer, G., Nguyen, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Renschler, M., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Shefali, S., Silva, M., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Strotjohann, N. L., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Tilav, S., Tischbein, F., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Unger, E., Elorrieta, M. A. Unland, Usner, M., Vandenbroucke, J., van Eijk, D., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Wandkowsky, N., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Williams, D. R., Wolf, M., Wood, T. R., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yoshida, S., Yuan, T., and Zhang, Z.
Subjects: High Energy Physics - Experiment, Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Phenomenology
Abstract: The flux of high-energy neutrinos passing through the Earth is attenuated due to their interactions with matter. The interaction rate is modulated by the neutrino interaction cross section and affects the flux arriving at the IceCube Neutrino Observatory, a cubic-kilometer neutrino detector embedded in the Antarctic ice sheet. We present a measurement of the neutrino cross section between 60 TeV and 10 PeV using the high-energy starting events (HESE) sample from IceCube with 7.5 years of data. The result is binned in neutrino energy and obtained using both Bayesian and frequentist statistics. We find it compatible with predictions from the Standard Model. Flavor information is explicitly included through updated morphology classifiers, proxies for the the three neutrino flavors. This is the first such measurement to use the three morphologies as observables and the first to account for neutrinos from tau decay., Comment: 10 pages, 7 figures, 2 tables. This article is supported by a long-form paper that discusses in high-energy starting event selection titled: "The IceCube high-energy starting event sample: Description and flux characterization with 7.5 years of data"
Published: 2020
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127. The IceCube high-energy starting event sample: Description and flux characterization with 7.5 years of data

Author: Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Alves Jr., A. A., Amin, N. M., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Axani, S., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Busse, R. S., Campana, M. A., Chen, C., Chirkin, D., Choi, S., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Evans, J., Evenson, P. A., Fahey, S., Fazely, A. R., Fiedlschuster, S., Fienberg, A. T., Filimonov, K., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Ghadimi, A., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Minh, M. Ha, Hanson, K., Hardin, J., Haungs, A., Hauser, S., Hebecker, D., Helbing, K., Henningsen, F., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Joppe, R., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katori, T., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kim, J., Kin, K., Kintscher, T., Kiryluk, J., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Krings, K., Krückl, G., Kulacz, N., Kurahashi, N., Kyriacou, A., Gualda, C. Lagunas, Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Li, Y., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mallik, P., Mancina, S., Mandalia, S., Mariş, I. C., Maruyama, R., Mase, K., McNally, F., Meagher, K., Medina, A., Meier, M., Meighen-Berger, S., Merz, J., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Naab, R., Nagai, R., Naumann, U., Necker, J., Neer, G., Nguyen, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Renschler, M., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Shefali, S., Silva, M., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Strotjohann, N. L., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Tilav, S., Tischbein, F., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Unger, E., Elorrieta, M. A. Unland, Vandenbroucke, J., van Eijk, D., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Wandkowsky, N., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Williams, D. R., Wolf, M., Wood, T. R., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yoshida, S., Yuan, T., and Zhang, Z.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract: The IceCube Neutrino Observatory has established the existence of a high-energy all-sky neutrino flux of astrophysical origin. This discovery was made using events interacting within a fiducial region of the detector surrounded by an active veto and with reconstructed energy above 60 TeV, commonly known as the high-energy starting event sample, or HESE. We revisit the analysis of the HESE sample with an additional 4.5 years of data, newer glacial ice models, and improved systematics treatment. This paper describes the sample in detail, reports on the latest astrophysical neutrino flux measurements, and presents a source search for astrophysical neutrinos. We give the compatibility of these observations with specific isotropic flux models proposed in the literature as well as generic power-law-like scenarios. Assuming $\nu_e:\nu_\mu:\nu_\tau=1:1:1$, and an equal flux of neutrinos and antineutrinos, we find that the astrophysical neutrino spectrum is compatible with an unbroken power law, with a preferred spectral index of ${2.87}^{+0.20}_{-0.19}$ for the $68.3\%$ confidence interval., Comment: 57 pages, 33 figures, 14 tables, additionally this work is accompanied by papers titled "Measurement of Astrophysical Tau Neutrinos in IceCube's High-Energy Starting Events" and "Measurement of the high-energy all-flavor neutrino-nucleon cross section with IceCube"
Published: 2020
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128. At Your Service: Coffee Beans Recommendation From a Robot Assistant

Author: de Berardinis, Jacopo, Pizzuto, Gabriella, Lanza, Francesco, Chella, Antonio, Meira, Jorge, and Cangelosi, Angelo
Subjects: Computer Science - Information Retrieval, Computer Science - Human-Computer Interaction
Abstract: With advances in the field of machine learning, precisely algorithms for recommendation systems, robot assistants are envisioned to become more present in the hospitality industry. Additionally, the COVID-19 pandemic has also highlighted the need to have more service robots in our everyday lives, to minimise the risk of human to-human transmission. One such example would be coffee shops, which have become intrinsic to our everyday lives. However, serving an excellent cup of coffee is not a trivial feat as a coffee blend typically comprises rich aromas, indulgent and unique flavours and a lingering aftertaste. Our work addresses this by proposing a computational model which recommends optimal coffee beans resulting from the user's preferences. Specifically, given a set of coffee bean properties (objective features), we apply different supervised learning techniques to predict coffee qualities (subjective features). We then consider an unsupervised learning method to analyse the relationship between coffee beans in the subjective feature space. Evaluated on a real coffee beans dataset based on digitised reviews, our results illustrate that the proposed computational model gives up to 92.7 percent recommendation accuracy for coffee beans prediction. From this, we propose how this computational model can be deployed on a service robot to reliably predict customers' coffee bean preferences, starting from the user inputting their coffee preferences to the robot recommending the coffee beans that best meet the user's likings., Comment: Extended version of submission to ACM HAI 2020
Published: 2020

129. Multimessenger Gamma-Ray and Neutrino Coincidence Alerts using HAWC and IceCube sub-threshold Data

Author: Solares, H. A. Ayala, Coutu, S., DeLaunay, J. J., Fox, D. B., Grégoire, T., Keivani, A., Krauß, F., Mostafá, M., Murase, K., Turley, C. F., Albert, A., Alfaro, R., Alvarez, C., Camacho, J. R. Angeles, Arteaga-Velázquez, J. C., Arunbabu, K. P., Rojas, D. Avila, Belmont-Moreno, E., Brisbois, C., Caballero-Mora, K. S., Carramiñana, A., Casanova, S., Cotti, U., De la Fuente, E., Hernandez, R. Diaz, Dingus, B. L., DuVernois, M. A., Durocher, M., Díaz-Vélez, J. C., Espinoza, C., Fan, K. L., Fleischhack, H., Fraija, N., Galván-Gámez, A., Garcia, D., García-González, J. A., Garfias, F., González, M. M., Goodman, J. A., Harding, J. P., Hona, B., Huang, D., Hueyotl-Zahuantitla, F., Huntemeyer, P., Iriarte, A., Jardin-Blicq, A., Joshi, V., Vargas, H. León, Linnemann, J. T., Longinotti, A. L., Luis-Raya, G., Lundeen, J., Malone, K., Martinez, O., Martinez-Castellanos, I., Martínez-Castro, J., Matthews, J. A., Miranda-Romagnoli, P., Moreno, E., Nellen, L., Newbold, M., Nisa, M. U., Noriega-Papaqui, R., Peisker, A., Pérez-Pérez, E. G., Rho, C. D., Rosa-González, D., Salazar, H., Greus, F. Salesa, Sandoval, A., Smith, A. J., Springer, R. W., Tollefson, K., Torres, I., Torres-Escobedo, R., Ureña-Mena, F., Villaseñor, L., Weisgarber, T., Willox, E., Zepeda, A., Zhou, H., de León, C., Aartsen, M. G., Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Amin, N. M., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Auffenberg, J., Axani, S., Bagherpour, H., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bohm, C., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Buscher, J., Busse, R. S., Carver, T., Chen, C., Cheung, E., Chirkin, D., Choi, S., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Dujmovic, H., Dunkman, M., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Evenson, P. A., Fahey, S., Fazely, A. R., Felde, J., Fienberg, A., Filimonov, K., Finley, C., Franckowiak, A., Friedman, E., Fritz, A., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Grant, D., Griffith, Z., Griswold, S., Günder, M., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hanson, K., Hardin, J., Haungs, A., Hauser, S., Hebecker, D., Heereman, D., Heix, P., Helbing, K., Hellauer, R., Henningsen, F., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Jonske, F., Joppe, R., Kang, D., Kang, W., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kim, J., Kin, K., Kintscher, T., Kiryluk, J., Kittler, T., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kowalski, M., Krings, K., Krückl, G., Kulacz, N., Kurahashi, N., Kyriacou, A., Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Li, Y., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Lünemann, J., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Maggi, G., Mahn, K. B. M., Makino, Y., Mallik, P., Mancina, S., Mariş, I. C., Maruyama, R., Mase, K., Maunu, R., McNally, F., Meagher, K., Medici, M., Medina, A., Meier, M., Meighen-Berger, S., Merz, J., Meures, T., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Muth, P., Nagai, R., Naumann, U., Neer, G., Nguyen, L. V., Niederhausen, H., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Murchadha, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pinat, E., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rauch, L., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Relethford, B., Renschler, M., Renzi, G., Resconi, E., Rhode, W., Richman, M., Riedel, B., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Shefali, S., Silva, M., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Song, M., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Strotjohann, N. L., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Terliuk, A., Tilav, S., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Ty, B., Unger, E., Elorrieta, M. A. Unland, Usner, M., Vandenbroucke, J., Van Driessche, W., van Eijk, D., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Wallraff, M., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Williams, D. R., Wills, L., Wolf, M., Wood, T. R., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yoshida, S., Yuan, T., Zhang, Z., and Zöcklein, M.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: The High Altitude Water Cherenkov (HAWC) and IceCube observatories, through the Astrophysical Multimessenger Observatory Network (AMON) framework, have developed a multimessenger joint search for extragalactic astrophysical sources. This analysis looks for sources that emit both cosmic neutrinos and gamma rays that are produced in photo-hadronic or hadronic interactions. The AMON system is running continuously, receiving sub-threshold data (i.e. data that is not suited on its own to do astrophysical searches) from HAWC and IceCube, and combining them in real-time. We present here the analysis algorithm, as well as results from archival data collected between June 2015 and August 2018, with a total live-time of 3.0 years. During this period we found two coincident events that have a false alarm rate (FAR) of $<1$ coincidence per year, consistent with the background expectations. The real-time implementation of the analysis in the AMON system began on November 20th, 2019, and issues alerts to the community through the Gamma-ray Coordinates Network with a FAR threshold of $<4$ coincidences per year., Comment: 14 pages, 5 figures, 3 tables
Published: 2020
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130. IceCube-Gen2: The Window to the Extreme Universe

Author: Collaboration, The IceCube-Gen2, Aartsen, M. G., Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Allison, P., Amin, N. M., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Arlen, T. C., Auffenberg, J., Axani, S., Bagherpour, H., Bai, X., V., A. Balagopal, Barbano, A., Bartos, I., Bastian, B., Basu, V., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bohm, C., Bohmer, M., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Burley, R. T., Buscher, J., Busse, R. S., Bustamante, M., Campana, M. A., Carnie-Bronca, E. G., Carver, T., Chen, C., Chen, P., Cheung, E., Chirkin, D., Choi, S., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., Deaconu, C., De Clercq, C., DeLaunay, J. J., De Kockere, S., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Evans, J. J., Evenson, P. A., Fahey, S., Farrag, K., Fazely, A. R., Felde, J., Fienberg, A. T., Filimonov, K., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia-Fernandez, D., Garrappa, S., Gartner, A., Gerhardt, L., Gernhaeuser, R., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hanson, J. C., Hanson, K., Hardin, J., Haugen, J., Haungs, A., Hauser, S., Hebecker, D., Heinen, D., Heix, P., Helbing, K., Hellauer, R., Henningsen, F., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, B., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Holzapfel, K., Hoshina, K., Huang, F., Huber, M., Huber, T., Huege, T., Hughes, K., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Jonske, F., Joppe, R., Kalekin, O., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katori, T., Katz, U., Kauer, M., Keivani, A., Kellermann, M., Kelley, J. L., Kheirandish, A., Kim, J., Kin, K., Kintscher, T., Kiryluk, J., Kittler, T., Kleifges, M., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Krauss, C. B., Krings, K., Krückl, G., Kulacz, N., Kurahashi, N., Gualda, C. Lagunas, Lahmann, R., Lanfranchi, J. L., Larson, M. J., Latif, U., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Li, Y., Liu, Q. R., Lohfink, E., LoSecco, J., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Lünemann, J., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Maggi, G., Mahn, K. B. M., Makino, Y., Mallik, P., Mancina, S., Mandalia, S., Mariş, I. C., Marka, S., Marka, Z., Maruyama, R., Mase, K., Maunu, R., McNally, F., Meagher, K., Medina, A., Meier, M., Meighen-Berger, S., Merz, J., Meyers, Z. S., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Muth, P., Naab, R., Nagai, R., Nam, J., Naumann, U., Necker, J., Neer, G., Nelles, A., Nguyên, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Oberla, E., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Sullivan, E., Pan, Y., Pandya, H., Pankova, D. V., Papp, L., Park, N., Parker, G. K., Paudel, E. N., Peiffer, P., Heros, C. Pérez de los, Petersen, T. C., Philippen, S., Pieloth, D., Pieper, S., Pinfold, J. L., Pizzuto, A., Plaisier, I., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rauch, L., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Renschler, M., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Riegel, M., Roberts, E. J., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Sandstrom, P., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Shaevitz, M. H., Sharma, A., Shefali, S., Silva, M., Smith, D., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Söldner-Rembold, S., Song, M., Southall, D., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Strotjohann, N. L., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Taketa, A., Tanaka, H. K. M., Tenholt, F., Ter-Antonyan, S., Terliuk, A., Tilav, S., Tollefson, K., Tomankova, L., Tönnis, C., Torres, J., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Unger, E., Elorrieta, M. A. Unland, Vandenbroucke, J., van Eijk, D., van Eijndhoven, N., Vannerom, D., van Santen, J., Veberic, D., Verpoest, S., Vieregg, A., Vraeghe, M., Walck, C., Watson, T. B., Weaver, C., Weindl, A., Weinstock, L., Weiss, M. J., Weldert, J., Welling, C., Wendt, C., Werthebach, J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Williams, D. R., Wissel, S. A., Wolf, M., Wood, T. R., Woschnagg, K., Wrede, G., Wren, S., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yoshida, S., Yuan, T., Zhang, Z., Zierke, S., and Zöcklein, M.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: The observation of electromagnetic radiation from radio to $\gamma$-ray wavelengths has provided a wealth of information about the universe. However, at PeV (10$^{15}$ eV) energies and above, most of the universe is impenetrable to photons. New messengers, namely cosmic neutrinos, are needed to explore the most extreme environments of the universe where black holes, neutron stars, and stellar explosions transform gravitational energy into non-thermal cosmic rays. The discovery of cosmic neutrinos with IceCube has opened this new window on the universe. In this white paper, we present an overview of a next-generation instrument, IceCube-Gen2, which will sharpen our understanding of the processes and environments that govern the universe at the highest energies. IceCube-Gen2 is designed to: 1) Resolve the high-energy neutrino sky from TeV to EeV energies; 2) Investigate cosmic particle acceleration through multi-messenger observations; 3) Reveal the sources and propagation of the highest energy particles in the universe; 4) Probe fundamental physics with high-energy neutrinos. IceCube-Gen2 will increase the annual rate of observed cosmic neutrinos by a factor of ten compared to IceCube, and will be able to detect sources five times fainter than its predecessor. Furthermore, through the addition of a radio array, IceCube-Gen2 will extend the energy range by several orders of magnitude compared to IceCube. Construction will take 8 years and cost about \$350M. The goal is to have IceCube-Gen2 fully operational by 2033. IceCube-Gen2 will play an essential role in shaping the new era of multi-messenger astronomy, fundamentally advancing our knowledge of the high-energy universe. This challenging mission can be fully addressed only in concert with the new survey instruments across the electromagnetic spectrum and gravitational wave detectors which will be available in the coming years., Comment: 56 pages, 29 figures
Published: 2020
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131. Measurements of the Time-Dependent Cosmic-Ray Sun Shadow with Seven Years of IceCube Data -- Comparison with the Solar Cycle and Magnetic Field Models

Author: Aartsen, M. G., Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Amin, N. M., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Auffenberg, J., Axani, S., Bagherpour, H., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bohm, C., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Buscher, J., Busse, R. S., Carver, T., Chen, C., Cheung, E., Chirkin, D., Choi, S., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Evenson, P. A., Fahey, S., Fazely, A. R., Felde, J., Fichtner, H., Fienberg, A. T., Filimonov, K., Finley, C., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Ghadimi, A., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Günder, M., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hanson, K., Hardin, J., Haungs, A., Hauser, S., Hebecker, D., Heereman, D., Heix, P., Helbing, K., Hellauer, R., Henningsen, F., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Jonske, F., Joppe, R., Kang, D., Kang, W., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kim, J., Kin, K., Kintscher, T., Kiryluk, J., Kittler, T., Kleimann, J., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kowalski, M., Krings, K., Krückl, G., Kulacz, N., Kurahashi, N., Kyriacou, A., Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Li, Y., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Lünemann, J., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Maggi, G., Mahn, K. B. M., Makino, Y., Mallik, P., Mancina, S., Mariş, I. C., Maruyama, R., Mase, K., Maunu, R., McNally, F., Meagher, K., Medici, M., Medina, A., Meier, M., Meighen-Berger, S., Merz, J., Meures, T., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Muth, P., Nagai, R., Naumann, U., Neer, G., Nguyen, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Murchadha, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pinat, E., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rauch, L., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Relethford, B., Renschler, M., Renzi, G., Resconi, E., Rhode, W., Richman, M., Riedel, B., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Shefali, S., Silva, M., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Song, M., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Strotjohann, N. L., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Terliuk, A., Tilav, S., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Ty, B., Unger, E., Elorrieta, M. A. Unland, Usner, M., Vandenbroucke, J., Van Driessche, W., van Eijk, D., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Wallraff, M., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Williams, D. R., Wills, L., Wolf, M., Wood, T. R., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yoshida, S., Yuan, T., Zhang, Z., and Zöcklein, M.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Solar and Stellar Astrophysics
Abstract: Observations of the time-dependent cosmic-ray Sun shadow have been proven as a valuable diagnostic for the assessment of solar magnetic field models. In this paper, seven years of IceCube data are compared to solar activity and solar magnetic field models. A quantitative comparison of solar magnetic field models with IceCube data on the event rate level is performed for the first time. Additionally, a first energy-dependent analysis is presented and compared to recent predictions. We use seven years of IceCube data for the Moon and the Sun and compare them to simulations on data rate level. The simulations are performed for the geometrical shadow hypothesis for the Moon and the Sun and for a cosmic-ray propagation model governed by the solar magnetic field for the case of the Sun. We find that a linearly decreasing relationship between Sun shadow strength and solar activity is preferred over a constant relationship at the 6.4sigma level. We test two commonly used models of the coronal magnetic field, both combined with a Parker spiral, by modeling cosmic-ray propagation in the solar magnetic field. Both models predict a weakening of the shadow in times of high solar activity as it is also visible in the data. We find tensions with the data on the order of $3\sigma$ for both models, assuming only statistical uncertainties. The magnetic field model CSSS fits the data slightly better than the PFSS model. This is generally consistent with what is found previously by the Tibet AS-gamma Experiment, a deviation of the data from the two models is, however, not significant at this point. Regarding the energy dependence of the Sun shadow, we find indications that the shadowing effect increases with energy during times of high solar activity, in agreement with theoretical predictions., Comment: 38 pages, 13 figures. Submitted
Published: 2020
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132. Searching for eV-scale sterile neutrinos with eight years of atmospheric neutrinos at the IceCube neutrino telescope

Author: Aartsen, M. G., Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Amin, N. M., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Auffenberg, J., Axani, S., Bagherpour, H., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bohm, C., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Buscher, J., Busse, R. S., Carver, T., Chen, C., Cheung, E., Chirkin, D., Choi, S., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Evenson, P. A., Fahey, S., Fazely, A. R., Fedynitch, A., Felde, J., Fienberg, A. T., Filimonov, K., Finley, C., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Günder, M., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hanson, K., Hardin, J., Haungs, A., Hauser, S., Hebecker, D., Heereman, D., Heix, P., Helbing, K., Hellauer, R., Henningsen, F., Hickford, S., Hignight, J., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Jonske, F., Joppe, R., Kang, D., Kang, W., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kim, J., Kintscher, T., Kiryluk, J., Kittler, T., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kowalski, M., Krings, K., Krückl, G., Kulacz, N., Kurahashi, N., Kyriacou, A., Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Li, Y., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Lünemann, J., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Maggi, G., Mahn, K. B. M., Makino, Y., Mallik, P., Mancina, S., Mariş, I. C., Maruyama, R., Mase, K., Maunu, R., McNally, F., Meagher, K., Medici, M., Medina, A., Meier, M., Meighen-Berger, S., Merz, J., Meures, T., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Muth, P., Nagai, R., Naumann, U., Neer, G., Nguyen, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Murchadha, A., O'Sullivan, E., Palczewski, T., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pinat, E., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rauch, L., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Relethford, B., Renschler, M., Renzi, G., Resconi, E., Rhode, W., Richman, M., Riedel, B., Robertson, S., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Shefali, S., Silva, M., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Song, M., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Stößl, A., Strotjohann, N. L., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Terliuk, A., Tilav, S., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Ty, B., Unger, E., Elorrieta, M. A. Unland, Usner, M., Vandenbroucke, J., Van Driessche, W., van Eijk, D., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Wallraff, M., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Williams, D. R., Wills, L., Wolf, M., Wood, T. R., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yodh, G., Yoshida, S., Yuan, T., Zhang, Z., and Zöcklein, M.
Subjects: High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract: We report in detail on searches for eV-scale sterile neutrinos, in the context of a 3+1 model, using eight years of data from the IceCube neutrino telescope. By analyzing the reconstructed energies and zenith angles of 305,735 atmospheric $\nu_\mu$ and $\bar{\nu}_\mu$ events we construct confidence intervals in two analysis spaces: $\sin^2 (2\theta_{24})$ vs. $\Delta m^2_{41}$ under the conservative assumption $\theta_{34}=0$; and $\sin^2(2\theta_{24})$ vs. $\sin^2 (2\theta_{34})$ given sufficiently large $\Delta m^2_{41}$ that fast oscillation features are unresolvable. Detailed discussions of the event selection, systematic uncertainties, and fitting procedures are presented. No strong evidence for sterile neutrinos is found, and the best-fit likelihood is consistent with the no sterile neutrino hypothesis with a p-value of 8\% in the first analysis space and 19\% in the second., Comment: This long-form paper is a companion to the letter "An eV-scale sterile neutrino search using eight years of atmospheric muon neutrino data from the IceCube Neutrino Observatory". v2: update other experiments contours on results plot
Published: 2020
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133. An eV-scale sterile neutrino search using eight years of atmospheric muon neutrino data from the IceCube Neutrino Observatory

Author: Aartsen, M. G., Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Amin, N. M., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Auffenberg, J., Axani, S., Bagherpour, H., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bohm, C., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Buscher, J., Busse, R. S., Carver, T., Chen, C., Cheung, E., Chirkin, D., Choi, S., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Evenson, P. A., Fahey, S., Fazely, A. R., Fedynitch, A., Felde, J., Fienberg, A. T., Filimonov, K., Finley, C., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Günder, M., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hanson, K., Hardin, J., Haungs, A., Hauser, S., Hebecker, D., Heereman, D., Heix, P., Helbing, K., Hellauer, R., Henningsen, F., Hickford, S., Hignight, J., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jones, B. J. P., Jonske, F., Joppe, R., Kang, D., Kang, W., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kim, J., Kintscher, T., Kiryluk, J., Kittler, T., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kowalski, M., Krings, K., Krückl, G., Kulacz, N., Kurahashi, N., Kyriacou, A., Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Li, Y., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Lünemann, J., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Maggi, G., Mahn, K. B. M., Makino, Y., Mallik, P., Mancina, S., Mariş, I. C., Maruyama, R., Mase, K., Maunu, R., McNally, F., Meagher, K., Medici, M., Medina, A., Meier, M., Meighen-Berger, S., Merz, J., Meures, T., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Muth, P., Nagai, R., Naumann, U., Neer, G., Nguyen, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Murchadha, A., O'Sullivan, E., Palczewski, T., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pinat, E., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rauch, L., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Relethford, B., Renschler, M., Renzi, G., Resconi, E., Rhode, W., Richman, M., Riedel, B., Robertson, S., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Shefali, S., Silva, M., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Song, M., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Stößl, A., Strotjohann, N. L., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Terliuk, A., Tilav, S., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Ty, B., Unger, E., Elorrieta, M. A. Unland, Usner, M., Vandenbroucke, J., Van Driessche, W., van Eijk, D., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Wallraff, M., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Williams, D. R., Wills, L., Wolf, M., Wood, T. R., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Xu, Y., Yanez, J. P., Yodh, G., Yoshida, S., Yuan, T., Zhang, Z., and Zöcklein, M.
Subjects: High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract: The results of a 3+1 sterile neutrino search using eight years of data from the IceCube Neutrino Observatory are presented. A total of 305,735 muon neutrino events are analyzed in reconstructed energy-zenith space to test for signatures of a matter-enhanced oscillation that would occur given a sterile neutrino state with a mass-squared differences between 0.01\,eV$^2$ and 100\,eV$^2$. The best-fit point is found to be at $\sin^2(2\theta_{24})=0.10$ and $\Delta m_{41}^2 = 4.5{\rm eV}^2$, which is consistent with the no sterile neutrino hypothesis with a p-value of 8.0\%., Comment: 11 pages, 5 figures. This letter is supported by the long-form paper "Searching for eV-scale sterile neutrinos with eight years of atmospheric neutrinos at the IceCube neutrino telescope," also appearing on arXiv. Digital data release available at: https://github.com/icecube/HE-Sterile-8year-data-release
Published: 2020
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134. IceCube Search for Neutrinos Coincident with Compact Binary Mergers from LIGO-Virgo's First Gravitational-Wave Transient Catalog

Author: Aartsen, M. G., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Auffenberg, J., Axani, S., Bagherpour, H., Bai, X., V., A. Balagopal, Barbano, A., Bartos, I., Barwick, S. W., Bastian, B., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bohm, C., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Buscher, J., Busse, R. S., Carver, T., Chen, C., Cheung, E., Chirkin, D., Choi, S., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Corley, K. R., Correa, P., Countryman, S., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Dharani, S., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., Dvorak, E., Eberhardt, B., Ehrhardt, T., Eller, P., Engel, R., Evenson, P. A., Fahey, S., Fazely, A. R., Felde, J., Filimonov, K., Finley, C., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Ghorbani, K., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Günder, M., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hanson, K., Haungs, A., Hauser, S., Hebecker, D., Heereman, D., Heix, P., Helbing, K., Hellauer, R., Henningsen, F., Hickford, S., Hignight, J., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jero, K., Jones, B. J. P., Jonske, F., Joppe, R., Kang, D., Kang, W., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Keivani, A., Kellermann, M., Kelley, J. L., Kheirandish, A., Kim, J., Kintscher, T., Kiryluk, J., Kittler, T., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kowalski, M., Krings, K., Krückl, G., Kulacz, N., Kurahashi, N., Kyriacou, A., Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczynska, A., Li, Y., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Lünemann, J., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Maggi, G., Mahn, K. B. M., Makino, Y., Mallik, P., Mallot, K., Mancina, S., Mariş, I. C., Marka, S., Marka, Z., Maruyama, R., Mase, K., Maunu, R., McNally, F., Meagher, K., Medici, M., Medina, A., Meier, M., Meighen-Berger, S., Merino, G., Merz, J., Meures, T., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Muth, P., Nagai, R., Naumann, U., Neer, G., Nguyen, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Murchadha, A., O'Sullivan, E., Palczewski, T., Pandya, H., Pankova, D. V., Park, N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pinat, E., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Price, P. B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rauch, L., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Relethford, B., Renschler, M., Renzi, G., Resconi, E., Rhode, W., Richman, M., Robertson, S., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Scharf, M., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Shefali, S., Silva, M., Snihur, R., Soedingrekso, J., Soldin, D., Song, M., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Stössl, A., Strotjohann, N. L., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Terliuk, A., Tilav, S., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Ty, B., Unger, E., Elorrieta, M. A. Unland, Usner, M., Vandenbroucke, J., Van Driessche, W., van Eijk, D., van Eijndhoven, N., van Santen, J., Verpoest, S., Veske, D., Vraeghe, M., Walck, C., Wallace, A., Wallraff, M., Wandkowsky, N., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Wille, L., Williams, D. R., Wills, L., Wolf, M., Wood, J., Wood, T. R., Woschnagg, K., Wrede, G., Wulff, J., Xu, D. L., Xu, X. W., Xu, Y., Yanez, J. P., Yodh, G., Yoshida, S., Yuan, T., and Zöcklein, M.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: Using the IceCube Neutrino Observatory, we search for high-energy neutrino emission coincident with compact binary mergers observed by the LIGO and Virgo gravitational wave (GW) detectors during their first and second observing runs. We present results from two searches targeting emission coincident with the sky localization of each gravitational wave event within a 1000 second time window centered around the reported merger time. One search uses a model-independent unbinned maximum likelihood analysis, which uses neutrino data from IceCube to search for point-like neutrino sources consistent with the sky localization of GW events. The other uses the Low-Latency Algorithm for Multi-messenger Astrophysics, which incorporates astrophysical priors through a Bayesian framework and includes LIGO-Virgo detector characteristics to determine the association between the GW source and the neutrinos. No significant neutrino coincidence is seen by either search during the first two observing runs of the LIGO-Virgo detectors. We set upper limits on the time-integrated neutrino emission within the 1000 second window for each of the 11 GW events. These limits range from 0.02-0.7 $\mathrm{GeV~cm^{-2}}$. We also set limits on the total isotropic equivalent energy, $E_{\mathrm{iso}}$, emitted in high-energy neutrinos by each GW event. These limits range from 1.7 $\times$ 10$^{51}$ - 1.8 $\times$ 10$^{55}$ erg. We conclude with an outlook for LIGO-Virgo observing run O3, during which both analyses are running in real time.
Published: 2020
Full Text: View/download PDF

135. IceCube Search for High-Energy Neutrino Emission from TeV Pulsar Wind Nebulae

Author: Aartsen, M. G., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Auffenberg, J., Axani, S., Bagherpour, H., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bohm, C., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Buscher, J., Busse, R. S., Carver, T., Chen, C., Cheung, E., Chirkin, D., Choi, S., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., Dvorak, E., Eberhardt, B., Ehrhardt, T., Eller, P., Engel, R., Evenson, P. A., Fahey, S., Fazely, A. R., Felde, J., Filimonov, K., Finley, C., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Ghorbani, K., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Günder, M., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hanson, K., Haungs, A., Hebecker, D., Heereman, D., Heix, P., Helbing, K., Hellauer, R., Henningsen, F., Hickford, S., Hignight, J., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jero, K., Jones, B. J. P., Jonske, F., Joppe, R., Kang, D., Kang, W., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kim, J., Kintscher, T., Kiryluk, J., Kittler, T., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Kowalski, M., Krings, K., Krückl, G., Kulacz, N., Kurahashi, N., Kyriacou, A., Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Li, Y., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Lünemann, J., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Maggi, G., Mahn, K. B. M., Makino, Y., Mallik, P., Mallot, K., Mancina, S., Mariş, I. C., Maruyama, R., Mase, K., Maunu, R., McNally, F., Meagher, K., Medici, M., Medina, A., Meier, M., Meighen-Berger, S., Merino, G., Meures, T., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Muth, P., Nagai, R., Naumann, U., Neer, G., Nguyen, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Murchadha, A., O'Sullivan, E., Palczewski, T., Pandya, H., Pankova, D. V., Park, N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pinat, E., Pizzuto, A., Plum, M., Porcelli, A., Price, P. B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rauch, L., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Relethford, B., Renschler, M., Renzi, G., Resconi, E., Rhode, W., Richman, M., Robertson, S., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Shefali, S., Silva, M., Snihur, R., Soedingrekso, J., Soldin, D., Song, M., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Stößl, A., Strotjohann, N. L., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Terliuk, A., Tilav, S., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Ty, B., Unger, E., Elorrieta, M. A. Unland, Usner, M., Vandenbroucke, J., Van Driessche, W., van Eijk, D., van Eijndhoven, N., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Wallraff, M., Wandkowsky, N., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Wille, L., Williams, D. R., Wills, L., Wolf, M., Wood, J., Wood, T. R., Woschnagg, K., Wrede, G., Wulff, J., Xu, D. L., Xu, X. W., Xu, Y., Yanez, J. P., Yodh, G., Yoshida, S., Yuan, T., and Zöcklein, M.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: Pulsar wind nebulae (PWNe) are the main gamma-ray emitters in the Galactic plane. They are diffuse nebulae that emit nonthermal radiation. Pulsar winds, relativistic magnetized outflows from the central star, shocked in the ambient medium produce a multiwavelength emission from the radio through gamma rays. Although the leptonic scenario is able to explain most PWNe emission, a hadronic contribution cannot be excluded. A possible hadronic contribution to the high-energy gamma-ray emission inevitably leads to the production of neutrinos. Using 9.5 yr of all-sky IceCube data, we report results from a stacking analysis to search for neutrino emission from 35 PWNe that are high-energy gamma-ray emitters. In the absence of any significant correlation, we set upper limits on the total neutrino emission from those PWNe and constraints on hadronic spectral components., Comment: 11 pages, 2 figures; matches the published version in ApJ
Published: 2020
Full Text: View/download PDF

136. Combined search for neutrinos from dark matter self-annihilation in the Galactic Centre with ANTARES and IceCube

Author: ANTARES Collaboration, Albert, A., André, M., Anghinolfi, M., Ardid, M., Aubert, J. -J., Aublin, J., Baret, B., Basa, S., Belhorma, B., Bertin, V., Biagi, S., Bissinger, M., Boumaaza, J., Bouta, M., Bouwhuis, M. C., Brânzaş, H., Bruijn, R., Brunner, J., Busto, J., Capone, A., Caramete, L., Carr, J., Celli, S., Chabab, M., Chau, T. N., Moursli, R. Cherkaoui El, Chiarusi, T., Circella, M., Coleiro, A., Colomer, M., Coniglione, R., Coyle, P., Creusot, A., Díaz, A. F., Deschamps, A., Distefano, C., Di Palma, I., Domi, A., Donzaud, C., Dornic, D., Drouhin, D., Eberl, T., Khayati, N. El, Enzenhöfer, A., Ettahiri, A., Fermani, P., Ferrara, G., Filippini, F., Fusco, L., Gay, P., Glotin, H., Gozzini, R., Ruiz, R. Gracia, Graf, K., Guidi, C., Hallmann, S., van Haren, H., Heijboer, A. J., Hello, Y., Hernández-Rey, J. J., Hößl, J., Hofestädt, J., Huang, F., Illuminati, G., James, C. W., de Jong, M., de Jong, P., Jongen, M., Kadler, M., Kalekin, O., Katz, U., Khan-Chowdhury, N. R., Kouchner, A., Kreykenbohm, I., Kulikovskiy, V., Lahmann, R., Breton, R. Le, Lefèvre, D., Leonora, E., Levi, G., Lincetto, M., Lopez-Coto, D., Loucatos, S., Maggi, G., Manczak, J., Marcelin, M., Margiotta, A., Marinelli, A., Martínez-Mora, J. A., Mele, R., Melis, K., Migliozzi, P., Moser, M., Moussa, A., Muller, R., Nauta, L., Navas, S., Nezri, E., Nielsen, C., Nuñez-Castiñeyra, A., O'Fearraigh, B., Organokov, M., Păvălaş, G. E., Pellegrino, C., Perrin-Terrin, M., Piattelli, P., Poirè, C., Popa, V., Pradier, T., Randazzo, N., Reck, S., Riccobene, G., Sánchez-Losa, A., Samtleben, D. F. E., Sanguineti, M., Sapienza, P., Schüssler, F., Spurio, M., Stolarczyk, Th., Strandberg, B., Taiuti, M., Tayalati, Y., Thakore, T., Tingay, S. J., Trovato, A., Vallage, B., Van Elewyck, V., Versari, F., Viola, S., Vivolo, D., Wilms, J., Zaborov, D., Zegarelli, A., Zornoza, J. D., Zúñiga, J., Collaboration, IceCube, Aartsen, M. G., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Auffenberg, J., Axani, S., Bagherpour, H., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bohm, C., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Buscher, J., Busse, R. S., Carver, T., Chen, C., Cheung, E., Chirkin, D., Choi, S., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., Dvorak, E., Eberhardt, B., Ehrhardt, T., Eller, P., Engel, R., Evenson, P. A., Fahey, S., Fazely, A. R., Felde, J., Filimonov, K., Finley, C., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Ghorbani, K., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Günder, M., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hanson, K., Haungs, A., Hebecker, D., Heereman, D., Heix, P., Helbing, K., Hellauer, R., Henningsen, F., Hickford, S., Hignight, J., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jero, K., Jones, B. J. P., Jonske, F., Joppe, R., Kang, D., Kang, W., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kim, J., Kintscher, T., Kiryluk, J., Kittler, T., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Kowalski, M., Krings, K., Krückl, G., Kulacz, N., Kurahashi, N., Kyriacou, A., Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Lünemann, J., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mallik, P., Mallot, K., Mancina, S., Mariş, I. C., Maruyama, R., Mase, K., Maunu, R., McNally, F., Meagher, K., Medici, M., Medina, A., Meier, M., Meighen-Berger, S., Merino, G., Meures, T., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Muth, P., Nagai, R., Naumann, U., Neer, G., Nguyen, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Murchadha, A., O'Sullivan, E., Palczewski, T., Pandya, H., Pankova, D. V., Park, N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pinat, E., Pizzuto, A., Plum, M., Porcelli, A., Price, P. B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rauch, L., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Relethford, B., Renschler, M., Renzi, G., Resconi, E., Rhode, W., Richman, M., Robertson, S., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Shefali, S., Silva, M., Snihur, R., Soedingrekso, J., Soldin, D., Song, M., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Stö\s{s}l, A., Strotjohann, N. L., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Terliuk, A., Tilav, S., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Ty, B., Unger, E., Elorrieta, M. A. Unland, Usner, M., Vandenbroucke, J., Van Driessche, W., van Eijk, D., van Eijndhoven, N., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Wallraff, M., Wandkowsky, N., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Wille, L., Williams, D. R., Wills, L., Wolf, M., Wood, J., Wood, T. R., Woschnagg, K., Wrede, G., Wulff, J., Xu, D. L., Xu, X. W., Xu, Y., Yanez, J. P., Yodh, G., Yoshida, S., Yuan, T., and Zöcklein, M.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: We present the results of the first combined dark matter search targeting the Galactic Centre using the ANTARES and IceCube neutrino telescopes. For dark matter particles with masses from 50 to 1000 GeV, the sensitivities on the self-annihilation cross section set by ANTARES and IceCube are comparable, making this mass range particularly interesting for a joint analysis. Dark matter self-annihilation through the $\tau^+\tau^-$, $\mu^+\mu^-$, $b\bar{b}$ and $W^+W^-$ channels is considered for both the Navarro-Frenk-White and Burkert halo profiles. In the combination of 2,101.6 days of ANTARES data and 1,007 days of IceCube data, no excess over the expected background is observed. Limits on the thermally-averaged dark matter annihilation cross section $\langle\sigma_A\upsilon\rangle$ are set. These limits present an improvement of up to a factor of two in the studied dark matter mass range with respect to the individual limits published by both collaborations. When considering dark matter particles with a mass of 200 GeV annihilating through the $\tau^+\tau^-$ channel, the value obtained for the limit is $7.44 \times 10^{-24} \text{cm}^{3}\text{s}^{-1}$ for the Navarro-Frenk-White halo profile. For the purpose of this joint analysis, the model parameters and the likelihood are unified, providing a benchmark for forthcoming dark matter searches performed by neutrino telescopes.
Published: 2020
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137. Characteristics of the diffuse astrophysical electron and tau neutrino flux with six years of IceCube high energy cascade data

Author: IceCube Collaboration, Aartsen, M. G., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Auffenberg, J., Axani, S., Backes, P., Bagherpour, H., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bohm, C., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Buscher, J., Busse, R. S., Carver, T., Chen, C., Cheung, E., Chirkin, D., Choi, S., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., Dvorak, E., Eberhardt, B., Ehrhardt, T., Eller, P., Engel, R., Evenson, P. A., Fahey, S., Fazely, A. R., Felde, J., Filimonov, K., Finley, C., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Ghorbani, K., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Günder, M., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hanson, K., Haungs, A., Hebecker, D., Heereman, D., Heix, P., Helbing, K., Hellauer, R., Henningsen, F., Hickford, S., Hignight, J., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jero, K., Jones, B. J. P., Jonske, F., Joppe, R., Kang, D., Kang, W., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Kheirandish, A., Kim, J., Kintscher, T., Kiryluk, J., Kittler, T., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Kowalski, M., Krings, K., Krückl, G., Kulacz, N., Kurahashi, N., Kyriacou, A., Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Lesiak-Bzdak, M., Leszczyńska, A., Leuermann, M., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Lünemann, J., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Maggi, G., Mahn, K. B. M., Makino, Y., Mallik, P., Mallot, K., Mancina, S., Mari{ş}, I. C., Maruyama, R., Mase, K., Maunu, R., McNally, F., Meagher, K., Medici, M., Medina, A., Meier, M., Meighen-Berger, S., Merino, G., Meures, T., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Muth, P., Nagai, R., Naumann, U., Neer, G., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Murchadha, A., O'Sullivan, E., Palczewski, T., Pandya, H., Pankova, D. V., Park, N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pinat, E., Pizzuto, A., Plum, M., Porcelli, A., Price, P. B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rauch, L., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Relethford, B., Renschler, M., Renzi, G., Resconi, E., Rhode, W., Richman, M., Robertson, S., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Rysewyk, D., Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Shefali, S., Silva, M., Snihur, R., Soedingrekso, J., Soldin, D., Song, M., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Stößl, A., Strotjohann, N. L., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Terliuk, A., Tilav, S., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Ty, B., Unger, E., Elorrieta, M. A. Unland, Usner, M., Vandenbroucke, J., Van Driessche, W., van Eijk, D., van Eijndhoven, N., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Wallraff, M., Wandkowsky, N., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Wille, L., Williams, D. R., Wills, L., Wolf, M., Wood, J., Wood, T. R., Woschnagg, K., Wrede, G., Xu, D. L., Xu, X. W., Xu, Y., Yanez, J. P., Yodh, G., Yoshida, S., Yuan, T., and Zöcklein, M.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: We report on the first measurement of the astrophysical neutrino flux using particle showers (cascades) in IceCube data from 2010 -- 2015. Assuming standard oscillations, the astrophysical neutrinos in this dedicated cascade sample are dominated ($\sim 90 \%$) by electron and tau flavors. The flux, observed in the sensitive energy range from $16\,\mathrm{TeV}$ to $2.6\,\mathrm{PeV}$, is consistent with a single power-law model as expected from Fermi-type acceleration of high energy particles at astrophysical sources. We find the flux spectral index to be $\gamma=2.53\pm0.07$ and a flux normalization for each neutrino flavor of $\phi_{astro} = 1.66^{+0.25}_{-0.27}$ at $E_{0} = 100\, \mathrm{TeV}$, in agreement with IceCube's complementary muon neutrino results and with all-neutrino flavor fit results. In the measured energy range we reject spectral indices $\gamma\leq2.28$ at $\ge3\sigma$ significance level. Due to high neutrino energy resolution and low atmospheric neutrino backgrounds, this analysis provides the most detailed characterization of the neutrino flux at energies below $\sim100\,{\rm{TeV}}$ compared to previous IceCube results. Results from fits assuming more complex neutrino flux models suggest a flux softening at high energies and a flux hardening at low energies (p-value $\ge 0.06$). The sizable and smooth flux measured below $\sim 100\,{\rm{TeV}}$ remains a puzzle. In order to not violate the isotropic diffuse gamma-ray background as measured by the Fermi-LAT, it suggests the existence of astrophysical neutrino sources characterized by dense environments which are opaque to gamma-rays., Comment: 4 figures, 4 tables, includes supplementary material
Published: 2020
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138. ANTARES and IceCube Combined Search for Neutrino Point-like and Extended Sources in the Southern Sky

Author: ANTARES Collaboration, Albert, A., André, M., Anghinolfi, M., Anton, G., Ardid, M., Aubert, J. -J., Aublin, J., Baret, B., Basa, S., Belhorma, B., Bertin, V., Biagi, S., Bissinger, M., Boumaaza, J., Bourret, S., Bouta, M., Bouwhuis, M. C., Brânzaş, H., Bruijn, R., Brunner, J., Busto, J., Capone, A., Caramete, L., Carr, J., Celli, S., Chabab, M., Chau, T. N., Moursli, R. Cherkaoui El, Chiarusi, T., Circella, M., Coleiro, A., Colomer, M., Coniglione, R., Costantini, H., Coyle, P., Creusot, A., Díaz, A. F., de Wasseige, G., Deschamps, A., Distefano, C., Di Palma, I., Domi, A., Donzaud, C., Dornic, D., Drouhin, D., Eberl, T., Bojaddaini, I. El, Khayati, N. El, Elsässer, D., Enzenhöfer, A., Ettahiri, A., Fassi, F., Fermani, P., Ferrara, G., Filippini, F., Fusco, L., Gay, P., Glotin, H., Gozzini, R., Ruiz, R. Gracia, Graf, K., Guidi, C., Hallmann, S., van Haren, H., Heijboer, A. J., Hello, Y., Hernández-Rey, J. J., Hößl, J., Hofestädt, J., Illuminati, G., James, C. W., de Jong, M., de Jong, P., Jongen, M., Kadler, M., Kalekin, O., Katz, U., Khan-Chowdhury, N. R., Kouchner, A., Kreter, M., Kreykenbohm, I., Kulikovskiy, V., Lahmann, R., Breton, R. Le, Lefèvre, D., Leonora, E., Levi, G., Lincetto, M., Lopez-Coto, D., Loucatos, S., Maggi, G., Manczak, J., Marcelin, M., Margiotta, A., Marinelli, A., Martínez-Mora, J. A., Mele, R., Melis, K., Migliozzi, P., Moser, M., Moussa, A., Muller, R., Nauta, L., Navas, S., Nezri, E., Nielsen, C., Nuñez-Castiñeyra, A., O'Fearraigh, B., Organokov, M., Păvălaş, G. E., Pellegrino, C., Perrin-Terrin, M., Piattelli, P., Poirè, C., Popa, V., Pradier, T., Quinn, L., Randazzo, N., Riccobene, G., Sánchez-Losa, A., Salah-Eddine, A., Samtleben, D. F. E., Sanguineti, M., Sapienza, P., Schüssler, F., Spurio, M., Stolarczyk, Th., Strandberg, B., Taiuti, M., Tayalati, Y., Thakore, T., Tingay, S. J., Trovato, A., Vallage, B., Van Elewyck, V., Versari, F., Viola, S., Vivolo, D., Wilms, J., Zaborov, D., Zegarelli, A., Zornoza, J. D., Zúñiga, J., Collaboration, IceCube, Aartsen, M. G., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Andeen, K., Anderson, T., Ansseau, I., Argüelles, C., Auffenberg, J., Axani, S., Backes, P., Bagherpour, H., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bohm, C., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Buscher, J., Busse, R. S., Carver, T., Chen, C., Cheung, E., Chirkin, D., Choi, S., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desiati, P., de Vries, K. D., de With, M., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., Dvorak, E., Eberhardt, B., Ehrhardt, T., Eller, P., Engel, R., Evenson, P. A., Fahey, S., Fazely, A. R., Felde, J., Filimonov, K., Finley, C., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Ghorbani, K., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Günder, M., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hanson, K., Haungs, A., Hebecker, D., Heereman, D., Heix, P., Helbing, K., Hellauer, R., Henningsen, F., Hickford, S., Hignight, J., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jero, K., Jones, B. J. P., Jonske, F., Joppe, R., Kang, D., Kang, W., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Kauer, M., Kelley, J. L., Kheirandish, A., Kim, J., Kintscher, T., Kiryluk, J., Kittler, T., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Kowalski, M., Krings, K., Krückl, G., Kulacz, N., Kurahashi, N., Kyriacou, A., Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Leuermann, M., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Lünemann, J., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mallik, P., Mallot, K., Mancina, S., Mariş, I. C., Maruyama, R., Mase, K., Maunu, R., McNally, F., Meagher, K., Medici, M., Medina, A., Meier, M., Meighen-Berger, S., Merino, G., Meures, T., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Muth, P., Nagai, R., Naumann, U., Neer, G., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Murchadha, A., O'Sullivan, E., Palczewski, T., Pandya, H., Pankova, D. V., Park, N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pinat, E., Pizzuto, A., Plum, M., Porcelli, A., Price, P. B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rauch, L., Rawlins, K., Rea, I. C., Reimann, R., Relethford, B., Renschler, M., Renzi, G., Resconi, E., Rhode, W., Richman, M., Robertson, S., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Rysewyk, D., Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seckel, D., Seunarine, S., Shefali, S., Silva, M., Snihur, R., Soedingrekso, J., Soldin, D., Song, M., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Stößl, A., Strotjohann, N. L., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Terliuk, A., Tilav, S., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Ty, B., Unger, E., Elorrieta, M. A. Unland, Usner, M., Vandenbroucke, J., Van Driessche, W., van Eijk, D., van Eijndhoven, N., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Wallraff, M., Wandkowsky, N., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Wille, L., Williams, D. R., Wills, L., Wolf, M., Wood, J., Wood, T. R., Woschnagg, K., Wrede, G., Xu, D. L., Xu, X. W., Xu, Y., Yanez, J. P., Yodh, G., Yoshida, S., Yuan, T., and Zöcklein, M.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: A search for point-like and extended sources of cosmic neutrinos using data collected by the ANTARES and IceCube neutrino telescopes is presented. The data set consists of all the track-like and shower-like events pointing in the direction of the Southern Sky included in the nine-year ANTARES point-source analysis, combined with the through-going track-like events used in the seven-year IceCube point-source search. The advantageous field of view of ANTARES and the large size of IceCube are exploited to improve the sensitivity in the Southern Sky by a factor $\sim$2 compared to both individual analyses. In this work, the Southern Sky is scanned for possible excesses of spatial clustering, and the positions of preselected candidate sources are investigated. In addition, special focus is given to the region around the Galactic Centre, whereby a dedicated search at the location of SgrA* is performed, and to the location of the supernova remnant RXJ 1713.7-3946. No significant evidence for cosmic neutrino sources is found and upper limits on the flux from the various searches are presented.
Published: 2020
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139. A search for IceCube events in the direction of ANITA neutrino candidates

Author: IceCube Collaboration, Aartsen, M. G., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alispach, C., Andeen, K., Anderson, T., Ansseau, I., Anton, G., Argüelles, C., Auffenberg, J., Axani, S., Backes, P., Bagherpour, H., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Baum, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bohm, C., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bourbeau, J., Bradascio, F., Braun, J., Bron, S., Brostean-Kaiser, J., Burgman, A., Buscher, J., Busse, R. S., Carver, T., Chen, C., Cheung, E., Chirkin, D., Choi, S., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dave, P., De Clercq, C., DeLaunay, J. J., Dembinski, H., Deoskar, K., De Ridder, S., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dujmovic, H., Dunkman, M., Dvorak, E., Eberhardt, B., Ehrhardt, T., Eller, P., Engel, R., Evenson, P. A., Fahey, S., Fazely, A. R., Felde, J., Filimonov, K., Finley, C., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Gaisser, T. K., Gallagher, J., Ganster, E., Garrappa, S., Gerhardt, L., Ghorbani, K., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Grant, D., Grégoire, T., Griffith, Z., Griswold, S., Günder, M., Gündüz, M., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hanson, K., Haungs, A., Hebecker, D., Heereman, D., Heix, P., Helbing, K., Hellauer, R., Henningsen, F., Hickford, S., Hignight, J., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hoinka, T., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jero, K., Jones, B. J. P., Jonske, F., Joppe, R., Kang, D., Kang, W., Kappes, A., Kappesser, D., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Kheirandish, A., Kim, J., Kintscher, T., Kiryluk, J., Kittler, T., Klein, S. R., Koirala, R., Kolanoski, H., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Kowalski, M., Krings, K., Krückl, G., Kulacz, N., Kurahashi, N., Kyriacou, A., Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Leonard, K., Leszczyńska, A., Leuermann, M., Liu, Q. R., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Lünemann, J., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Maggi, G., Mahn, K. B. M., Makino, Y., Mallik, P., Mallot, K., Mancina, S., Mariş, I. C., Maruyama, R., Mase, K., Maunu, R., McNally, F., Meagher, K., Medici, M., Medina, A., Meier, M., Meighen-Berger, S., Merino, G., Meures, T., Micallef, J., Mockler, D., Momenté, G., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Muth, P., Nagai, R., Naumann, U., Neer, G., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D. R., Pollmann, A. Obertacke, Oehler, M., Olivas, A., O'Murchadha, A., O'Sullivan, E., Palczewski, T., Pandya, H., Pankova, D. V., Park, N., Peiffer, P., Heros, C. Pérez de los, Philippen, S., Pieloth, D., Pieper, S., Pinat, E., Pizzuto, A., Plum, M., Porcelli, A., Price, P. B., Przybylski, G. T., Raab, C., Raissi, A., Rameez, M., Rauch, L., Rawlins, K., Rea, I. C., Rehman, A., Reimann, R., Relethford, B., Renschler, M., Renzi, G., Resconi, E., Rhode, W., Richman, M., Robertson, S., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Rysewyk, D., Safa, I., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Schaufel, M., Schieler, H., Schlunder, P., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Sclafani, S., Seunarine, S., Shefali, S., Silva, M., Snihur, R., Soedingrekso, J., Soldin, D., Song, M., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R. G., Stößl, A., Strotjohann, N. L., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Tenholt, F., Ter-Antonyan, S., Terliuk, A., Tilav, S., Tollefson, K., Tomankova, L., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Ty, B., Unger, E., Elorrieta, M. A. Unland, Usner, M., Vandenbroucke, J., Van Driessche, W., van Eijk, D., van Eijndhoven, N., van Santen, J., Verpoest, S., Vraeghe, M., Walck, C., Wallace, A., Wallraff, M., Wandkowsky, N., Watson, T. B., Weaver, C., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Whelan, B. J., Whitehorn, N., Wiebe, K., Wiebusch, C. H., Wille, L., Williams, D. R., Wills, L., Wolf, M., Wood, J., Wood, T. R., Woschnagg, K., Wrede, G., Xu, D. L., Xu, X. W., Xu, Y., Yanez, J. P., Yodh, G., Yoshida, S., Yuan, T., and Zöcklein, M.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Phenomenology
Abstract: During the first three flights of the Antarctic Impulsive Transient Antenna (ANITA) experiment, the collaboration detected several neutrino candidates. Two of these candidate events were consistent with an ultra-high-energy up-going air shower and compatible with a tau neutrino interpretation. A third neutrino candidate event was detected in a search for Askaryan radiation in the Antarctic ice, although it is also consistent with the background expectation. The inferred emergence angle of the first two events is in tension with IceCube and ANITA limits on isotropic cosmogenic neutrino fluxes. Here, we test the hypothesis that these events are astrophysical in origin, possibly caused by a point source in the reconstructed direction. Given that any ultra-high-energy tau neutrino flux traversing the Earth should be accompanied by a secondary flux in the TeV-PeV range, we search for these secondary counterparts in seven years of IceCube data using three complementary approaches. In the absence of any significant detection, we set upper limits on the neutrino flux from potential point sources. We compare these limits to ANITA's sensitivity in the same direction and show that an astrophysical explanation of these anomalous events under standard model assumptions is severely constrained regardless of source spectrum.
Published: 2020
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140. Correction: Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical models

Author: Centonze, Matteo, Di Conza, Giusy, Lahn, Michael, Fabregat, Isabel, Dituri, Francesco, Gigante, Isabella, Serino, Grazia, Scialpi, Rosanna, Carrieri, Livianna, Negro, Roberto, Pizzuto, Elena, and Giannelli, Gianluigi
Published: 2023
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141. Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical models

Author: Centonze, Matteo, Di Conza, Giusy, Lahn, Michael, Fabregat, Isabel, Dituri, Francesco, Gigante, Isabella, Serino, Grazia, Scialpi, Rosanna, Carrieri, Livianna, Negro, Roberto, Pizzuto, Elena, and Giannelli, Gianluigi
Published: 2023
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142. Near-field terahertz nonlinear optics with blue light

Author: Pizzuto, Angela, Ma, Pingchuan, and Mittleman, Daniel M.
Published: 2023
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143. SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape

Author: Starr, Tyler N, Czudnochowski, Nadine, Liu, Zhuoming, Zatta, Fabrizia, Park, Young-Jun, Addetia, Amin, Pinto, Dora, Beltramello, Martina, Hernandez, Patrick, Greaney, Allison J, Marzi, Roberta, Glass, William G, Zhang, Ivy, Dingens, Adam S, Bowen, John E, Tortorici, M Alejandra, Walls, Alexandra C, Wojcechowskyj, Jason A, De Marco, Anna, Rosen, Laura E, Zhou, Jiayi, Montiel-Ruiz, Martin, Kaiser, Hannah, Dillen, Josh R, Tucker, Heather, Bassi, Jessica, Silacci-Fregni, Chiara, Housley, Michael P, di Iulio, Julia, Lombardo, Gloria, Agostini, Maria, Sprugasci, Nicole, Culap, Katja, Jaconi, Stefano, Meury, Marcel, Dellota Jr, Exequiel, Abdelnabi, Rana, Foo, Shi-Yan Caroline, Cameroni, Elisabetta, Stumpf, Spencer, Croll, Tristan I, Nix, Jay C, Havenar-Daughton, Colin, Piccoli, Luca, Benigni, Fabio, Neyts, Johan, Telenti, Amalio, Lempp, Florian A, Pizzuto, Matteo S, Chodera, John D, Hebner, Christy M, Virgin, Herbert W, Whelan, Sean PJ, Veesler, David, Corti, Davide, Bloom, Jesse D, and Snell, Gyorgy
Subjects: Medical Microbiology, Biomedical and Clinical Sciences, Immunology, Vaccine Related, Lung, Prevention, Biodefense, Pneumonia & Influenza, Emerging Infectious Diseases, Immunization, Pneumonia, Biotechnology, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Good Health and Well Being, Adult, Aged, Animals, Antibodies, Monoclonal, Antibodies, Viral, Antibody Affinity, Broadly Neutralizing Antibodies, COVID-19, COVID-19 Vaccines, Cell Line, Cricetinae, Cross Reactions, Epitopes, B-Lymphocyte, Female, Humans, Immune Evasion, Male, Mesocricetus, Middle Aged, Models, Molecular, SARS-CoV-2, Spike Glycoprotein, Coronavirus, Vaccinology, COVID-19 Drug Treatment, General Science & Technology
Abstract: An ideal therapeutic anti-SARS-CoV-2 antibody would resist viral escape1-3, have activity against diverse sarbecoviruses4-7, and be highly protective through viral neutralization8-11 and effector functions12,13. Understanding how these properties relate to each other and vary across epitopes would aid the development of therapeutic antibodies and guide vaccine design. Here we comprehensively characterize escape, breadth and potency across a panel of SARS-CoV-2 antibodies targeting the receptor-binding domain (RBD). Despite a trade-off between in vitro neutralization potency and breadth of sarbecovirus binding, we identify neutralizing antibodies with exceptional sarbecovirus breadth and a corresponding resistance to SARS-CoV-2 escape. One of these antibodies, S2H97, binds with high affinity across all sarbecovirus clades to a cryptic epitope and prophylactically protects hamsters from viral challenge. Antibodies that target the angiotensin-converting enzyme 2 (ACE2) receptor-binding motif (RBM) typically have poor breadth and are readily escaped by mutations despite high neutralization potency. Nevertheless, we also characterize a potent RBM antibody (S2E128) with breadth across sarbecoviruses related to SARS-CoV-2 and a high barrier to viral escape. These data highlight principles underlying variation in escape, breadth and potency among antibodies that target the RBD, and identify epitopes and features to prioritize for therapeutic development against the current and potential future pandemics.
Published: 2021

144. 1115: ESSENTIAL PEDIATRIC LIFE SUPPORT SKILLS: A SET OF ROLLING CART-BASED SIMULATIONS IN THE PICU

Author: Pizzuto, Matthew, Wen, Elias, Riley, Isabelle, Cross, Jaclyn, and Joyner, Benny
Published: 2024
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145. 1096: UTILIZING SIMULATION TO IMPROVE PEDIATRIC CRITICAL CARE FELLOW COMFORT WITH TRANSPORT CONSULTS

Author: Riley, Isabelle, Pizzuto, Matthew, and Shea, Paul
Published: 2024
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146. Near-field terahertz nonlinear optics with blue light

Author: Angela Pizzuto, Pingchuan Ma, and Daniel M. Mittleman
Subjects: Applied optics. Photonics, TA1501-1820, Optics. Light, QC350-467
Abstract: Abstract The coupling of terahertz optical techniques to scattering-type scanning near-field microscopy (s-SNOM) has recently emerged as a valuable new paradigm for probing the properties of semiconductors and other materials on the nanoscale. Researchers have demonstrated a family of related techniques, including terahertz nanoscopy (elastic scattering, based on linear optics), time-resolved methods, and nanoscale terahertz emission spectroscopy. However, as with nearly all examples of s-SNOM since the technique’s inception in the mid-1990s, the wavelength of the optical source coupled to the near-field tip is long, usually at energies of 2.5 eV or less. Challenges in coupling of shorter wavelengths (i.e., blue light) to the nanotip has greatly inhibited the study of nanoscale phenomena in wide bandgap materials such as Si and GaN. Here, we describe the first experimental demonstration of s-SNOM using blue light. With femtosecond pulses at 410 nm, we generate terahertz pulses directly from bulk silicon, spatially resolved with nanoscale resolution, and show that these signals provide spectroscopic information that cannot be obtained using near-infrared excitation. We develop a new theoretical framework to account for this nonlinear interaction, which enables accurate extraction of material parameters. This work establishes a new realm of possibilities for the study of technologically relevant wide-bandgap materials using s-SNOM methods.
Published: 2023
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147. Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity

Author: Thomson, Emma C, Rosen, Laura E, Shepherd, James G, Spreafico, Roberto, da Silva Filipe, Ana, Wojcechowskyj, Jason A, Davis, Chris, Piccoli, Luca, Pascall, David J, Dillen, Josh, Lytras, Spyros, Czudnochowski, Nadine, Shah, Rajiv, Meury, Marcel, Jesudason, Natasha, De Marco, Anna, Li, Kathy, Bassi, Jessica, O’Toole, Aine, Pinto, Dora, Colquhoun, Rachel M, Culap, Katja, Jackson, Ben, Zatta, Fabrizia, Rambaut, Andrew, Jaconi, Stefano, Sreenu, Vattipally B, Nix, Jay, Zhang, Ivy, Jarrett, Ruth F, Glass, William G, Beltramello, Martina, Nomikou, Kyriaki, Pizzuto, Matteo, Tong, Lily, Cameroni, Elisabetta, Croll, Tristan I, Johnson, Natasha, Di Iulio, Julia, Wickenhagen, Arthur, Ceschi, Alessandro, Harbison, Aoife M, Mair, Daniel, Ferrari, Paolo, Smollett, Katherine, Sallusto, Federica, Carmichael, Stephen, Garzoni, Christian, Nichols, Jenna, Galli, Massimo, Hughes, Joseph, Riva, Agostino, Ho, Antonia, Schiuma, Marco, Semple, Malcolm G, Openshaw, Peter JM, Fadda, Elisa, Baillie, J Kenneth, Chodera, John D, Investigators, The ISARIC4C, Consortium, the COVID-19 Genomics UK, Rihn, Suzannah J, Lycett, Samantha J, Virgin, Herbert W, Telenti, Amalio, Corti, Davide, Robertson, David L, and Snell, Gyorgy
Subjects: Medical Microbiology, Biomedical and Clinical Sciences, Biological Sciences, Immunology, Pneumonia, Prevention, Infectious Diseases, Vaccine Related, Immunization, Pneumonia & Influenza, Biodefense, Biotechnology, Emerging Infectious Diseases, Lung, 2.1 Biological and endogenous factors, Aetiology, Infection, Good Health and Well Being, Angiotensin-Converting Enzyme 2, Antibodies, Neutralizing, Antibodies, Viral, COVID-19, Genetic Fitness, Humans, Immune Evasion, Mutation, Phylogeny, SARS-CoV-2, Spike Glycoprotein, Coronavirus, Virulence, ISARIC4C Investigators, COVID-19 Genomics UK (COG-UK) Consortium, N439K, Spike, monoclonal antibody escape, mutation, protein structure, receptor binding motif, variant, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences
Abstract: SARS-CoV-2 can mutate and evade immunity, with consequences for efficacy of emerging vaccines and antibody therapeutics. Here, we demonstrate that the immunodominant SARS-CoV-2 spike (S) receptor binding motif (RBM) is a highly variable region of S and provide epidemiological, clinical, and molecular characterization of a prevalent, sentinel RBM mutation, N439K. We demonstrate N439K S protein has enhanced binding affinity to the hACE2 receptor, and N439K viruses have similar in vitro replication fitness and cause infections with similar clinical outcomes as compared to wild type. We show the N439K mutation confers resistance against several neutralizing monoclonal antibodies, including one authorized for emergency use by the US Food and Drug Administration (FDA), and reduces the activity of some polyclonal sera from persons recovered from infection. Immune evasion mutations that maintain virulence and fitness such as N439K can emerge within SARS-CoV-2 S, highlighting the need for ongoing molecular surveillance to guide development and usage of vaccines and therapeutics.
Published: 2021

148. Author Correction: Spatial communication systems across languages reflect universal action constraints

Author: Coventry, Kenny R., Gudde, Harmen B., Diessel, Holger, Collier, Jacqueline, Guijarro-Fuentes, Pedro, Vulchanova, Mila, Vulchanov, Valentin, Todisco, Emanuela, Reile, Maria, Breunesse, Merlijn, Plado, Helen, Bohnemeyer, Juergen, Bsili, Raed, Caldano, Michela, Dekova, Rositsa, Donelson, Katharine, Forker, Diana, Park, Yesol, Pathak, Lekhnath Sharma, Peeters, David, Pizzuto, Gabriella, Serhan, Baris, Apse, Linda, Hesse, Florian, Hoang, Linh, Hoang, Phuong, Igari, Yoko, Kapiley, Keerthana, Haupt-Khutsishvili, Tamar, Kolding, Sara, Priiki, Katri, Mačiukaitytė, Ieva, Mohite, Vaisnavi, Nahkola, Tiina, Tsoi, Sum Yi, Williams, Stefan, Yasuda, Shunei, Cangelosi, Angelo, Duñabeitia, Jon Andoni, Mishra, Ramesh Kumar, Rocca, Roberta, Šķilters, Jurģis, Wallentin, Mikkel, Žilinskaitė-Šinkūnienė, Eglė, and Incel, Ozlem Durmaz
Published: 2024
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149. From single words to compositional language via gestures : applications in robot language learning

Author: Pizzuto, Gabriella, Brown, Gavin, and Cangelosi, Angelo
Subjects: 006.3, robotics, applied machine learning, cognitive developmental robotics, computational modelling
Abstract: Infant development is remarkable during the first years of life. Cognitive growth is accelerated, with one of the key areas being language and communication. Language development in children is multimodal and cumulative. In terms of language growth, infants go from using gestures, to early words and combining these with gestures, until they form multi-word phrases. In fact, gestures and speech are integrated. Our research is fuelled by the fact that language is the most natural interface for humans to interact and yet is still in its infancy when it comes to human-robot interaction through natural language. This provides a rich source of inspiration and motivation for modelling early language acquisition on robotic platforms. Our work presents developmental robotics models leading to a novel framework focusing on the transition from single words to multi-words. This thesis first introduces a cognitive model that leverages the mask regional convolutional network for gesture-word comprehension on the iCub humanoid robot. The model is evaluated on a gesture-object dataset collected as part of our work. One of our key scientific contributions is the integration of a two-stage cascaded mask regional convolutional neural network with a matrix completion framework to model the single word to multi-word transition aided by a deictic gesture. The structured cognitive architecture is deployed on the iCub to illustrate its applicability for modelling language acquisition on an embodied agent. Our results further strengthen the capabilities of these frameworks. This thesis concludes by outlining how our contribution formulates potential guidelines for future efforts in robotic models of early language acquisition. Our work gives a computational model of moving from single words to compositional language, by exploiting current state-of-the-art machine learning techniques to realise this.
Published: 2020

150. Normal Values for Echocardiographic Myocardial Work in a Large Pediatric Population

Author: Pietro Marchese, Marco Scalese, Nadia Assanta, Eliana Franchi, Cecilia Viacava, Giuseppe Santoro, Giulia Corana, Alessandra Pizzuto, Francesca Valeria Contini, Shelby Kutty, and Massimiliano Cantinotti
Subjects: myocardial work, normal values, echocardiography, children, Medicine (General), R5-920
Abstract: Background: Echocardiographic myocardial work is a new load-independent echocardiographic technique to quantify left ventricle (LV) systolic performance. Our aim was to establish normal values for echocardiographic myocardial work in a large population of healthy children. Methods: For all the subjects 4-, 2-, and 3-chamber-view videos were stored. The following parameters were obtained by offline analysis: the global myocardial work (GMW), the global myocardial constructive work (GCW), the global myocardial wasted work (GWW), and the global myocardial work efficiency (GWE). Age, weight, height, heart rate, and body surface area (BSA) were used as independent variables in the statistical analysis. Results: In all, 516 healthy subjects (age range, 1 day—18 years; median age, 8.2 ± 5.3 years; 55.8% male; body surface area (BSA) range, 0.16 to 2.12 m2) were included. GWI, GCW, and GWW increased with weight, height, and BSA (ρ ranging from 0.635 to 0.226, p all < 0.01); GWI and GCW positively correlated with age (ρ 0.653 and 0.507). After adjusting for BSA differences, females showed higher mean GWI (p = 0.002) and GCW values (p < 0.001), thus Z-score equations for gender have been presented. Conclusions: We provided MW values in a large population of healthy pediatric subjects including lower ages. MW values increased with age and body size and, interestingly, were higher in females than in men. These data cover a gap in current nomograms and may serve as a baseline for the evaluation of MW analysis in children with congenital and acquired heart diseases.
Published: 2024
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