101. Multicolor imaging in macular telangiectasia-a comparison with fundus autofluorescence
- Author
-
Jay Chhablani, Dinah Zur, Dhanya V Nair, Roberto Gallego-Pinazo, Alessandro Invernizzi, Carlo Cagini, Sumit Randhir Singh, Mariano Cozzi, Samantha Fraser-Bell, Anand Rajendran, Vishal Govindahari, Apoorva Ayachit, Rosa Dolz Marco, Unnikrishnan Nair, and Marco Lupidi
- Subjects
medicine.medical_specialty ,Fundus Oculi ,Retinal crystals ,behavioral disciplines and activities ,Fundus autofluorescence ,Retina ,03 medical and health sciences ,Cellular and Molecular Neuroscience ,0302 clinical medicine ,Atrophy ,Ophthalmology ,mental disorders ,0502 economics and business ,medicine ,Humans ,Stage (cooking) ,Fluorescein Angiography ,Macular telangiectasia ,Retinal pigment epithelium ,Diabetic Retinopathy ,business.industry ,Confocal-scanning laser ophthalmoscopy ,05 social sciences ,medicine.disease ,Multicolor imaging ,Sensory Systems ,Ophthalmoscopy ,medicine.anatomical_structure ,Clinical diagnosis ,030221 ophthalmology & optometry ,Retinal Telangiectasis ,050211 marketing ,business ,human activities ,Tomography, Optical Coherence - Abstract
To describe various clinical features of idiopathic juxtafoveal retinal telangiectasis group 2A or idiopathic macular telangiectasia type 2 (MacTel) on multicolor imaging (MCI) and compare imaging findings of MacTel on MCI with fundus autofluorescence (FAF). Patients with a clinical diagnosis of MacTel based on Gass and Blodi’s classification were included. FAF and MCI images were graded qualitatively for stage of disease, margins of involvement, hyperautofluorescence on FAF (corresponding retinal atrophy on MCI), and detection of crystals. FAF and MCI were graded quantitatively for the area and number of quadrants involved, hypoautofluorescene on FAF (corresponding intraretinal pigment hyperplasia or retinal pigment epithelium [RPE] atrophy on MCI), and foci of right-angled venules. Seventy-eight eyes of forty five patients were included with both imaging modalities showing no difference with respect to staging of non-proliferative MacTel. Retinal crystals were recognized on MCI but not on FAF. Neurosensory retinal atrophy and subretinal neovascular membranes were detected using MCI with 92.3 and 83.3% sensitivity, respectively. Intraretinal pigmented hyperplasia was more accurately detected (70.1 vs 58.4%) compared with RPE atrophy on MCI. MCI showed larger area of involvement, higher number of quadrants involved (p
- Published
- 2020