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1,049 results on '"McDonnell, John"'

101. Issues in the Transition from School to Adult Services: A Survey of Parents of Secondary Students with Severe Handicaps. Specialized Training Program. Model School and Community Services for People with Severe Handicaps.

Author

Oregon Univ., Eugene. Center on Human Development. and McDonnell, John J.

Abstract

Parental projections of service needs and their ranking of features they perceived as important in vocational and residential programs for their handicapped son/daughter were assessed through a written questionnaire. A total of 163 questionnaires were completed and returned by parents of high school students with moderate and severe handicaps. The questionnaire consisted of nine items that asked parents to provide demographic information, to rank features of vocational and day services most likely to influence selection of a program, to rank features of residential services most likely to influence program selection, and to rank generic adult service programs their children would need immediately upon graduation, five years after graduation, and ten years after graduation. Parents overwhelmingly ranked vocational/day programs as the top priority for their children upon graduation and for the next 10 years. Long-term structured employment models providing a wide range of work opportunities and contact with nonhandicapped peers were the preferred alternative. Residential programs were more important five to ten years after graduation. Case management services were seen as important at two points in a student's transition from school to adult services: prior to graduation and as parents grow older and less able to act as their children's overseer. Data also verified the inadequacy of information for parents about adult services. (YLB)

Published
1983

102. The Improving Community-Based Instruction Project: Final Report.

Author

Utah Univ., Salt Lake City. Dept. of Special Education. and McDonnell, John

Abstract

The final report describes activities of the Improving Community-Based Instruction Project, which conducted research to improve the effectiveness and efficiency of training in community settings with individuals with severe disabilities. Three areas of research were undertaken: (1) studies of the influence of the location of instruction on the acquisition and generalization of community activities; (2) studies on strategies for establishing reliable stimulus control of student responses in community settings; and (3) studies on the impact of various strategies for building performance of complex chains of behavior. The project also developed procedural manuals to assist practitioners in developing community-based and classroom-based instructional programs. The report lists project objectives and briefly reports project activities and accomplishments. Among conclusions are the need for more comparative research on effectiveness of commonly recommended instructional strategies; examination of strategies leading to the adoption of validated techniques by practitioners; and research on instructional strategies to enhance maintenance of performance in community settings. Much of the document consists of attachments including the specific reports for studies in the three designated research areas, the two procedural manuals, and a program analysis form. Contains 34 references. (DB)

Published
1987

103. Teachers' Career Stages and Availability and Appropriateness of Incentives in Teaching.

Author

McDonnell, John H.

Abstract

Evidence on teachers' careers suggests that there are identifiable career stages through which teachers progress. Inherent in these career stages is the need for differentiated teacher incentives and development programs. The premise that the stages of development are important in planning effective professional incentives and development programs is well accepted. A model describing the dynamics of teachers' career cycles offers a view of career progression which reflects influences from environmental factors, both personal and organizational. The components of the career cycle are: (1) preservice, (2) induction, (3) competency building, (4) enthusiastic and growing, (5) career frustration, (6) stable and stagnant, (7) career wind-down, and (8) career exit. Appropriate incentives for each of these career stages are discussed. (JD)

Published
1989

104. Instruction for Students with Severe Disabilities in General Education Settings.

Author

McDonnell, John

Abstract

Discusses some of the issues associated with effective instruction for students with severe disabilities enrolled in general education classes. It is argued that developing a valid technology of instruction will require the field to reconceptualize our current model of teaching and learning for this group of students. (Author/CR)

Published
1998

105. Impact 7 of the Title VI Programs in the State of Oregon, September 1972-August 1973.

Author

Oregon State Board of Education, Salem., Oregon State System of Higher Education, Monmouth. Teaching Research Div., and McDonnell, John J.

Abstract

Described and evaluated are the 21 programs funded by Title VI for eight handicapping categories comprising 1,024 children at all educational levels in Oregon during 1972-1973. Explained are criteria such as adequacy of documented needs established by the state Board of Education for funding projects and training procedures for utilization of a Third Party Evaluation Model. The following are among results discussed: number of projects per category such as eight projects for the emotionally disturbed (ED), five projects for the speech and language impaired, and two projects each for the educable mentally retarded (EMR) and preschool children; costs; kinds of services such as a classroom utilizing behavior modification to offset undesirable behaviors learned at home; and conclusions stressing success of resource rooms for ED and EMR students, regular class placement, preschool programs, parent training programs, paraprofessionals for language remediation. Recommendations emphasized the need for further data on effects of integration, and encouragement of proposals featuring vocational educational skills. Given for each project are the title, location (a map is included), population served, funding allocation, dates, background information, objectives and evaluation plan, methodology, the Third Party Evaluator's comments, and pertinent tables or forms. (MC)

Published
1973

106. Impact 8 of the Title VI Programs in the State of Oregon: September 1, 1973-August 1974.

Author

Oregon State System of Higher Education, Portland., Oregon State Dept. of Education, Salem., and McDonnell, John J.

Abstract

Nineteen projects that served seven different classes of handicapped were funded for 1973-74 in Oregon under Title VI of the Elementary and Secondary Education Act of 1965. Six projects were funded for the emotionally disturbed, four projects for the hearing impaired, two projects for the developmentally disabled, two projects for the visually impaired, and one each for the trainable mentally retarded and the preschool handicapped. The projects served 1,650 children at a cost of $247,045. A careful examination of the 19 projects funded supported the following conclusions: that resource rooms demonstrated themselves to be efficient ways to serve emotionally disturbed children; that, given appropriate training and technical assistance, classroom teachers could cope with behavior problems in the classroom; that the use of volunteer aides with both speech and visually impaired children in areas where teachers were working on an itinerant basis continued to demonstrate itself to be an effective technique; and that a project serving developmentally disabled high school youth demonstrated that work experience skills could be taught effectively to such children. (Author/GW)

Published
1974

107. Summary of Impact of Title VI-B Funds on the Education of Oregon's Handicapped Children, June 1968-June 1973.

Author

Oregon State Dept. of Education, Salem., Oregon State System of Higher Education, Monmouth. Teaching Research Div., and McDonnell, John J.

Abstract

Summarized are results of a survey to determine the impact of 133 projects funded through Elementary and Secondary Education Act Title VI-B funds on handicapped children in Oregon by examining the number of children being served, the number of staff, and the number of dollars being expended. Significant findings are listed such as that deaf, blind, and trainable mentally retarded populations would not have been served if Title VI-B had not been available between 1968 and 1970, and that 87 percent of projects funded for an academic year were still in operation compared to only 44 percent of projects funded for the summer only. Among the 11 recommendations are that Title VI-B monies be awarded as seed money only and that the new special education service priorities be established every 3 years. General information includes report purpose, a summary of Title VI provisions, definitions of handicapping conditions, a description of eligible agencies, program purpose, program guidelines, evaluation model, and methodology. Seventeen tables are provided giving statistics such as the number and percentage of children served by handicapping condition. Five special projects are individually described including "A Study of the Extreme Learning Problem Program in Oregon." Appended are the questionnaire used in the survey and the cover letter. (DB)

Published
1973

108. Perspectives on the Future of IDEA.

Author

Hardman, Michael L., McDonnell, John, and Welch, Marshall

Abstract

This article addresses whether or not the assumptions upon which the Individuals with Disabilities Act (IDEA) is based remain valid as we approach the 21st century. Eligibility and labeling, free and appropriate public education, the individualized education program, and the least restrictive environment requirements are examined, and recommendations are made. (Author/CR)

Published
1997

109. Academic Engaged Time of Students with Low-Incidence Disabilities in General Education Classes.

Author

McDonnell, John

Abstract

Academic engaged time of six children with low-incidence disabilities in general education elementary classes was compared to six students without disabilities from the same classes and six students without disabilities from different, non-inclusive classes. No significant differences were found between academic responding and task management behaviors; however, differences were significant in rates of competing behavior. (Author/CR)

Published
1997

111. Transition Programs for Students with Moderate/Severe Disabilities.

Author

McDonnell, John and McDonnell, John

Abstract

This text is intended to provide new and practicing professionals with an introduction to the strategies necessary to support the transition of students with moderate and severe disabilities from school to community life. It offers recommendations for designing and implementing middle school, high school, and post-high school programs, addressing the full range of curricular and instructional issues at each of these levels. The book's five sections address: foundations of transition programs, curriculum and individualized planning, instruction and personal supports, preparation for home and community life, and preparation for work. The 13 chapters discuss the following topics: (1) expected outcomes and emerging values; (2) the role of secondary education in transition; (3) curriculum; (4) developing Individualized Education Program Plans; (5) participation in content-area classes; (6) teaching in natural settings; (7) developing leisure and recreational options; (8) preparation for life at home and in the community; (9) self-management; (10) employment training; (11) job placement; (12) administrative issues; and (13) interagency collaboration. Chapters are organized around focus questions, have illustrative case examples, and provide extensive references. Appendixes outline a curriculum for a school and community integration program and present checklists for evaluating the program. (DB)

Published
1996

113. Rural Students with Low Incidence Disabilities: Recommended Practices for the Future.

Author

Sebastian, Joan and McDonnell, John

Abstract

Strategies for educating students with low-incidence disabilities in rural schools include inclusion, peer- and community-referenced curriculum, student-centered educational planning, instruction in actual performance settings, positive behavioral support, and transdisciplinary teams. In Utah, the state office of education, universities, and school districts have collaborated to disseminate effective practices to rural educators working with low-incidence disability students. (LP)

Published
1995

115. The Role of Local Transition Councils in Rural Communities.

Author

Clark, Gary M. and McDonnell, John

Abstract

Addresses the feasibility of developing rural community transition councils to improve transition services for students with disabilities. Describes the role of local transition councils in relation to the context of rural communities and transition services. Includes suggestions for enhancing community cohesiveness and community capacity to support development of quality transition services. (LP)

Published
1994

116. Impact of Community-Based Instruction on the Development of Adaptive Behavior of Secondary-Level Students with Mental Retardation.

Author

McDonnell, John

Abstract

This study of community-based instruction with 34 high school students with moderate to profound mental retardation found (1) students made significant gains in 3 of 4 independent behavior domains; and (2) amount of community-based instruction was a more powerful predictor of gains than were intelligence quotient, level of student ambulation, or the presence of behavior problems. (Author/DB)

Published
1993

119. Nationals-Padres game halted and will not resume tonight after gunshots outside Nationals Park

Author

McDonnell, John

Subjects
Nationals Park -- Safety and security measures, Shooting -- Investigations, Baseball (Professional) -- Competitions -- Safety and security measures, Company legal issue, General interest, News, opinion and commentary, San Diego Padres -- Competitions, Washington Nationals -- Competitions
Abstract

Byline: John McDonnell Saturday night's game between the Washington Nationals and San Diego Padres was halted after a report of multiple gunshots outside Nationals Park. Two people were shot, according [...]

Published
2021

120. Vitamin D and cause-specific vascular disease and mortality: a Mendelian randomisation study involving 99,012 Chinese and 106,911 European adults

Author

Huang, Tao, Afzal, Shoaib, Yu, Canqing, Guo, Yu, Bian, Zheng, Yang, Ling, Millwood, Iona Y., Walters, Robin G., Chen, Yiping, Chen, Ningyu, Gao, Ruqin, Chen, Junshi, Clarke, Robert, Chen, Zhengming, Ellervik, Christina, Nordestgaard, Børge G., Lv, Jun, Li, Liming, Collins, Rory, Peto, Richard, Avery, Daniel, Boxall, Ruth, Bennett, Derrick, Chang, Yumei, Du, Huaidong, Gilbert, Simon, Hacker, Alex, Hill, Mike, Holmes, Michael, Iona, Andri, Kartsonaki, Christiana, Kerosi, Rene, Kong, Ling, Kurmi, Om, Lancaster, Garry, Lewington, Sarah, Lin, Kuang, McDonnell, John, Nie, Qunhua, Radhakrishnan, Jayakrishnan, Ryder, Paul, Sansome, Sam, Schmidt, Dan, Sherliker, Paul, Sohoni, Rajani, Stevens, Becky, Turnbull, Iain, Wang, Jenny, Wang, Lin, Wright, Neil, Yang, Xiaoming, Han, Xiao, Hou, Can, Pei, Pei, Liu, Chao, Tan, Yunlong, Pang, Zengchang, Li, Shanpeng, Wang, Shaojie, Liu, Yongmei, Du, Ranran, Zang, Yajing, Cheng, Liang, Tian, Xiaocao, Zhang, Hua, Zhai, Yaoming, Ning, Feng, Sun, Xiaohui, Li, Feifei, Lv, Silu, Wang, Junzheng, Hou, Wei, Zeng, Mingyuan, Jiang, Ge, Zhou, Xue, Yang, Liqiu, He, Hui, Yu, Bo, Li, Yanjie, Xu, Qinai, Kang, Quan, Guo, Ziyan, Wang, Dan, Hu, Ximin, Chen, Jinyan, Fu, Yan, Fu, Zhenwang, Wang, Xiaohuan, Weng, Min, Guo, Zhendong, Wu, Shukuan, Li, Yilei, Li, Huimei, Fu, Zhifang, Wu, Ming, Zhou, Yonglin, Zhou, Jinyi, Tao, Ran, Yang, Jie, Su, Jian, Liu, Fang, Zhang, Jun, Hu, Yihe, Lu, Yan, Ma, Liangcai, Tang, Aiyu, Zhang, Shuo, Jin, Jianrong, Liu, Jingchao, Tang, Zhenzhu, Chen, Naying, Huang, Ying, Li, Mingqiang, Meng, Jinhuai, Pan, Rong, Jiang, Qilian, Lan, Jian, Liu, Yun, Wei, Liuping, Zhou, Liyuan, Wang, Ping, Meng, Fanwen, Qin, Yulu, Wang, Sisi, Wu, Xianping, Zhang, Ningmei, Zhou, Weiwei, Luo, Guojin, Li, Jianguo, Chen, Xiaofang, Zhong, Xunfu, Liu, Jiaqiu, Sun, Qiang, Ge, Pengfei, Ren, Xiaolan, Dong, Caixia, Zhang, Hui, Mao, Enke, Wang, Xiaoping, Wang, Tao, Zhang, Xi, Zhang, Ding, Zhou, Gang, Feng, Shixian, Chang, Liang, Fan, Lei, Gao, Yulian, He, Tianyou, Sun, Huarong, Hu, Chen, Zhang, Xukui, Wu, Huifang, He, Pan, Yu, Min, Hu, Ruying, Wang, Hao, Qian, Yijian, Wang, Chunmei, Xie, Kaixu, Chen, Lingli, Zhang, Yidan, Pan, Dongxia, Gu, Qijun, Huang, Yuelong, Chen, Biyun, Yin, Li, Liu, Huilin, Fu, Zhongxi, Xu, Qiaohua, Xu, Xin, Zhang, Hao, Long, Huajun, Li, Xianzhi, Zhang, Libo, and Qiu, Zhe

Subjects
Adult, medicine.medical_specialty, lcsh:Medicine, Disease, Lower risk, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, Causal effect, Vitamin D and neurology, Humans, Medicine, Vascular Diseases, 030212 general & internal medicine, Myocardial infarction, Vitamin D, Mendelian randomisation, Stroke, business.industry, Vascular disease, Confounding, lcsh:R, General Medicine, Vitamin D Deficiency, medicine.disease, Lipids, 3. Good health, Cardiovascular diseases, Population study, Gene-Environment Interaction, business, 030217 neurology & neurosurgery, Research Article
Abstract

Background Randomised control trials and genetic analyses have demonstrated that vitamin D or 25-hydroxyvitamin D (25[OH]D) levels may not play a causal role in the development of cardiovascular disease. However, it is unclear if 25(OH)D is causally associated with cause-specific vascular disease and lipids. Therefore, we examined the causal association of 25(OH)D with myocardial infarction, stroke, ischaemic heart disease, ischaemic stroke, subarachnoid haemorrhage, intracerebral haemorrhage, and lipid levels among both Chinese and Europeans. Methods We used a Mendelian randomisation (MR) design in the China Kadoorie Biobank, the Copenhagen City Heart Study, and the Copenhagen General Population Study. The 25(OH)D-related genetic variants in the CYP2R1 and DCHR7 genes were genotyped in 99,012 Chinese adults and 106,911 Danish adults. Results In Chinese adults, plasma 25(OH)D levels were not significantly associated with cause-specific vascular disease or mortality, with the exception of intracerebral haemorrhage (HR, 1.09 [95% CI, 1.01,1.18] per 25 nmol/L higher plasma 25(OH)D). In Europeans, plasma 25(OH)D levels were inversely associated with all types of vascular diseases and mortality. However, MR analysis did not demonstrate causal associations of genetically increased 25(OH)D levels with cause-specific vascular diseases, or mortality in both Chinese and European adults. In addition, each 25 nmol/L higher 25(OH)D was observationally associated with lower total cholesterol and low-density lipoprotein cholesterol levels, but higher high-density lipoprotein cholesterol levels. Likewise, MR analysis showed that 25(OH)D levels were not causally associated with lipids in both Chinese and European adults after Bonferroni correction. Conclusions We found no evidence to support that genetically increased 25(OH)D was associated with a lower risk of ischaemic stroke, intracerebral haemorrhage, subarachnoid haemorrhage, and lipid levels in both Chinese and European adults. These results suggest that the inverse associations of vitamin D with vascular disease could be the result of confounding. Electronic supplementary material The online version of this article (10.1186/s12916-019-1401-y) contains supplementary material, which is available to authorized users.

Published
2019
Full Text
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121. A Comparison of Serial and Concurrent Sequencing Strategies in Teaching Generalized Grocery Item Location to Students with Moderate Handicaps.

Author

Ferguson, Brad and McDonnell, John

Abstract

This study, with six high school students with moderate to severe disabilities, found that students who received concurrent sequence training demonstrated better generalized performance in three nontrained grocery stores than students who had received serial sequence training, once training criterion was attained though training required more trials and minutes of instruction. (Author/DB)

Published
1991

122. Variables Associated with In-School and After-School Integration of Secondary Students with Severe Disabilities.

Author

McDonnell, John

Abstract

This study with 39 secondary students with severe disabilities integrated into regular programs in either home schools or cluster programs found that the proportion of students residing outside the normal school boundaries and the percent of students classified as Severely Multiply Handicapped were both negatively associated with both in-school and afterschool integration. (Author/DB)

Published
1991

128. Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors

Author

Bakker, Mark K., van der Spek, Rick A.A., van Rheenen, Wouter, Morel, Sandrine, Bourcier, Romain, Hostettler, Isabel C., Alg, Varinder S., van Eijk, Kristel R., Koido, Masaru, Akiyama, Masato, Terao, Chikashi, Matsuda, Koichi, Walters, Robin G., Lin, Kuang, Li, Liming, Millwood, Iona Y., Chen, Zhengming, Rouleau, Guy A., Zhou, Sirui, Rannikmäe, Kristiina, Sudlow, Cathie L.M., Houlden, Henry, van den Berg, Leonard H., Dina, Christian, Naggara, Olivier, Gentric, Jean-Christophe, Shotar, Eimad, Eugène, François, Desal, Hubert, Winsvold, Bendik S., Børte, Sigrid, Johnsen, Marianne Bakke, Brumpton, Ben M., Sandvei, Marie Søfteland, Willer, Cristen J., Hveem, Kristian, Zwart, John-Anker, Verschuren, W. M. Monique, Friedrich, Christoph M., Hirsch, Sven, Schilling, Sabine, Dauvillier, Jérôme, Martin, Olivier, Martinsen, Amy E, Aamodt, Anne Hege, Skogholt, Anne Heidi, Sandset, Else Charlotte, Kristoffersen, Espen S, Ellekjaer, Hanne, Heuch, Ingrid, Nielsen, Jonas Bille, Hagen, Knut, Fritsche, Lars, Thomas, Laurent F., Pedersen, Linda, Gabrielsen, Maiken E, Vigeland, Maria Dehli, Holmen, Oddgeir, Zhou, Wei, Chen, Junshi, Chen (PI), Zhengming, Clarke, Robert, Collins, Rory, Guo, Yu, Li (PI), Liming, Liu, Depei, Lv, Jun, Peto, Richard, Walters, Robin, Avery, Daniel, Boxall, Ruth, Bennett, Derrick, Chang, Yumei, Chen, Yiping, Du, Huaidong, Gan, Wei, Gilbert, Simon, Hacker, Alex, Hill, Michael, Holmes, Michael, Iona, Andri, Kartsonaki, Christiana, Kerosi, Rene, Kong, Ling, Lancaster, Garry, Lewington, Sarah, McDonnell, John, Millwood, Iona, Nie, Qunhua, Ryder, Paul, Sansome, Sam, Schmidt-Valle, Dan, Sherliker, Paul, Sohoni, Rajani, Stevens, Becky, Turnbull, Iain, Wang, Lin, Wright, Neil, Yang, Ling, Yang, Xiaoming, Yao, Pang, Bian, Zheng, Han, Xiao, Hou, Can, Pei, Pei, Liu, Chao, Yu, Canqing, Pang, Zengchang, Gao, Ruqin, Li, Shanpeng, Wang, Shaojie, Liu, Yongmei, Du, Ranran, Cheng, Liang, Tian, Xiaocao, Zhang, Hua, Zhai, Yaoming, Ning, Feng, Sun, Xiaohui, Li, Feifei, Lv, Silu, Wang, Junzheng, Hou, Wei, Zou, Mingyuan, Yan, Shichun, Zhou, Xue, Yu, Bo, Li, Yanjie, Xu, Qinai, Kang, Quan, Guo, Ziyan, Wang, Dan, Hu, Ximin, Chen, Jinyan, Fu, Yan, Wang, Xiaohuan, Weng, Min, Guo, Zhendong, Wu, Shukuan, Li, Yilei, Li, Huimei, Wu, Ming, Zhou, Yonglin, Zhou, Jinyi, Tao, Ran, Yang, Jie, Su, Jian, liu, Fang, Zhang, Jun, Hu, Yihe, Lu, Yan, Ma, Liangcai, Tang, Aiyu, Hua, Yujie, Jin, Jianrong, Liu, Jingchao, Tang, Zhenzhu, Chen, Naying, Huang, Ying, Li, Mingqiang, Meng, Jinhuai, Pan, Rong, Jiang, Qilian, Lan, Jian, Liu, Yun, Wei, Liuping, Zhou, Liyuan, Chen, Ningyu, Wang, Ping, Meng, Fanwen, Qin Sisi Wang, Yulu, Wu, Xianping, Zhang, Ningmei, Chen, Xiaofang, Zhou, Weiwei, Luo, Guojin, Li, Jianguo, Zhong, Xunfu, Liu, Jiaqiu, Sun, Qiang, Ge, Pengfei, Ren, Xiaolan, Dong, Caixia, Zhang, Hui, Mao, Enke, Wang, Xiaoping, Wang, Tao, Zhang, Xi, Zhou, Ding Zhang, Zhou, Gang, Feng, Shixian, Chang, Ling, Fan, Lei, Gao, Yulian, He, Tianyou, Sun, Huarong, He, Pan, Hu, Chen, Zhang, Xukui, Wu, Huifang, Yu, Min, Hu, Ruying, Wang, Hao, Gong, Weiwei, Wang, Meng, Xie, Kaixu, Chen, Lingli, Pan, Dongxia, Gu, Qijun, Huang, Yuelong, Chen, Biyun, Yin, Li, Liu, Huilin, Fu, Zhongxi, Xu, Qiaohua, Xu, Xin, Zhang, Hao, Long, Huajun, Zhang, Libo, Nagai, Akiko, Muto, Kaori, Hirata, Makoto, Morisaki, Takayuki, Yamashita, Yasushi, Kamatani, Yoichiro, Kambara, Yoko, Murakami, Yoshinori, Masumoto, Akihide, Nagayama, Satoshi, Miki, Yoshio, Yoshimori, Kozo, Fujioka, Tomoaki, Takata, Ryo, Yamaji, Ken, Takahashi, Kazuhisa, Asai, Satoshi, Takahashi, Yasuo, Minami, Shiro, Yamaguchi, Hiroki, Koretsune, Yukihiro, Nishizawa, Yasuko, Kodama, Ken, Kutsumi, Hiromu, Suzuki, Takao, Sinozaki, Nobuaki, Murayama, Shigeo, Furukawa, Yoichi, Yamanashi, Yuji, Papagiannaki, Chrisanthi, Piotin, Michel, Trystram, Denis, Edjlali-Goujon, Myriam, Boulouis, Grégoire, Rodriguez, Christine, Hassen, Waghi Ben, Saleme, Suzanna, Mounayer, Charbel, Rouchaud, Aymeric, Levrier, Olivier, Aguettaz, Pierre, Combaz, Xavier, Pasco, Anne, l’Allinec, Vincent, Bintner, Marc, Molho, Marc, Pascale, Gauthier, Chivot, Cyril, Costalat, Vincent, Darganzil, Cyril, Bonafé, Alain, Januel, Anne Christine, Michelozzi, Caterina, Cognard, Christophe, Bonneville, Fabrice, Tall, Philippe, Darcourt, Jean, Biondi, Alessandra, Iosif, Cristina, Ferre, Jean Christophe, Gauvrit, Jean Yves, Eugene, François, Raoult, Hélène, Gentric, Jean Christophe, Ognard, Julien, Anxionnat, René, Gory, Benjamin, Bracard, Serge, Derelle, Anne Laure, Tonnelet, Romain, Spelle, Laurent, Ikka, Léon, Ozanne, Augustin, Gallas, Sophie, Caroff, Jildaz, Achour, Nidal Ben, Moret, Jacques, Chabert, Emmanuel, Berge, Jérôme, Marnat, Gaultier, Barreau, Xavier, Gariel, Florent, Clarencon, Frédéric, Aggour, Mohammed, Ricolfi, Frédéric, Chavent, Adrien, Thouant, Pierre, Lebidinsky, Pablo, Lemogne, Brivael, Herbreteau, Denis, Bibi, Richard, Janot, Kevin, Pierot, Laurent, Soize, Sébastien, Labeyrie, Marc Antoine, Vandendries, Christophe, Kazemi, Appoline, Leclerc, Xavier, Pruvo, Jean Pierre, Bricout, Nicolas, Velasco, Stéphane, Boucebci, Samy, Lemmens, Robin, Pandolfo, Massimo, Bodenant, Marie, Louillet, Fabien, Mas, Jean-Louis, Deltour, Sandrine, Leder, Sara, Léger, Anne, Canaple, Sandrine, Godefroy, Olivier, Giroud, Maurice, Jacquin, Agnès, Moulin, Thierry, Vuillier, Fabrice, Tzourio, Christophe, Santos, Michael Dos, Malik, Rainer, Hausser, Ingrid, Thomas-Feles, Constanze, Weber, Ralf, Grond-Ginsbach, Caspar, Hacke, Werner, Giossi, Alessia, Volonghi, Irene, Costa, Paolo, del Zotto, Elisabetta, Morotti, Andrea, Poli, Loris, Muiesan, Maria Lorenza, Salvetti, Massimo, Rosei, Enrico Agabiti, Lanfranconi, Silvia, Baron, Pierluigi, Ferrarese, Carlo, Susani, Emanuela, Giacalone, Giacomo, Paolucci, Stefano, Palmirotta, Raffaele, Guadagni, Fiorella, Paciaroni, Maurizio, Ballabio, Elena, Parati, Eugenio A., Fluri, Felix, Hatz, Florian, Gisler, Dominique, Amort, Margareth, Bevan, Steve, James, Tom, Olsson, Sandra, Holmegaard, Lukas, Altintas, Ayse, Martin, Juan José, Kittner, Steven, Mitchell, Braxton, Stine, Colin, O’Connell, Jeff, Dueker, Nicole, Koudstaal, Peter J., de Lau, Lonneke M.L., Hofman, Albert, Verhaaren, Benjamin F, Uitterlinden, Andre G, Montaner, Joan, Mendioroz, Maite, Yadav, Sunaina, Khan, Muhammad Saleem, Wilder, Michael, van Dijk, Ewoud, Maaijwee, Noortje, Rutten-Jacobs, Loes, Kramer, Jamie, Malik, Shaneela, Brott, Thomas G, Brown, Robert D, Singleton, Andrew, Hardy, John, Rich, Stephen S, Tanislav, Christian, Jungehülsing, Jan, Werring, David, Alg, Varinder, Hostettler, Isabel, Bonner, Stephen, Walsh, Daniel, Bulters, Diederik, Kitchen, Neil, Brown, Martin, Grieve, Joan, Roberts, Gareth, Jones, Timothy, Critchley, Giles, Sharma, Pankaj, Nelson, Richard, Whitfield, Peter, Ross, Stuart, Patel, Hiren, Eldridge, Paul, Saastamoinen, Kari, Patel, Umang, Lawrance, Enas, Vandabona, Subha, Mendelow, David, Teal, Rachel, Warner, Orlando, Kirkpatrick, Peter, Seshadri, Sudha, Kilarski, Laura, Hyacinth, Hyacinth I, Oliveira, Jamary, Marini, Sandro, Nyquist, Paul, Lewis, Cathryn, Norrving, Bo, Smith, Gustav, Rosand, Jonathan, Biffi, Alessandro, Kourkoulis, Christina, Anderson, Chris, Giese, Anne-Katrin, Bang, Oh Young, Chung, Jong-Won, Kim, Gyeong-Moon, Zhuang, Qishuai, Sheu, Wayne, Smalley, June, Howson, Joanna, Granata, Alessandra, Markus, Hugh, Wardlaw, Joanna, Cole, John, Thalamuthu, Anbupalam, Hopewell, Jemma, Worrall, Bradford, Bis, Josh, Tirschwell, David, Reiner, Alex, Dhar, Raj, Lee, Jin-Moo, Mortenson, Janne, Wassertheil-Smoller, Sylvia, Prasad, Kameshwar, Fisher, Mark, Traenka, Christopher, Wang, Xingwu, Wang, Yongjun, Rouanet, Francois, Sibon, Igor, Sarnowski, Chloé, Maillard, Pauline, Aparicio, Hugo Javier, Dupuis, Josee, Yang, Qiong, Luvizutto, Gustavo, Chasman, Daniel, Rexrode, Kathryn, Harriot, Andrea, Phuah, Chia-Ling, Santo, Gustavo, Gerard, Jen, Liu, Guiyou, Aaron, Sanjith, Christudass, Christhunesa S., Salomi, BSB, Sanghera, Dharambir, Boehme, Amelia, Elkind, Mitchell, Gretarsdottir, Solveig, Lange, Leslie, Rost, Natalia, James, Michael, Stewart, Jill, Goldstein, Larry, Waddy, Salina, Vojinovic, Dina, Ikram, Arfan, Thijs, Vincent, Parati, Eugenio, Boncoraglio, Giorgio, Kooperberg, Charles, Abboud, Sherrine, Zand, Ramin, Bijlenga, Philippe, Selim, Magdy, Happola, Olli, Strbian, Daniel, Tomppo, Liisa, Pathak, Abhishek, Pfeiffer, Dorothea, Aires, de Buenos, de Carvalho, Joao Jose Freitas, Ribeiro, Priscila, Torres, Nuria, Barboza, Miguel, Plomaritoglou, Androniki, Bjorkegren, Johan, Chan, Yu-Feng Yvonne, Gudnason, Villi, Jimenez-Conde, Jordi, Soriano, Carolina, Roquer, Jaume, Bentley, Paul, Tournier-Lasserve, Elisabeth, Dufouil, Carole, Debette, Stephanie, Mishra, Aniket, Wee, Lawrence, Siddiqi, Saima, Wu, Jer-Yuarn, Ko, Tai-Ming, Bione, Silvia, Jood, Katarina, Tatlisumak, Turgut, Arauz, Antonio, Korostynski, Michal, Launer, Lenore, Yue, Suo, bersano, anna, Juchniewicz, Karol Józef, Mateusz, Adamski, Pera, Joanna, Wnuk, Marcin, Levi, Christopher, Gusdon, Aaron, Kostulas, Konstantinos, Maxwell, Jessye, Duering, Marco, Jagiella, Jeremiasz, Hata, Jun, Ninomiya, Toshiharu, Nguyen, Vinh, Thorarinsson, Bjorn Logi, Lee, Tsong-Hai, Rakitko, Alexandr, Dichgans, Martin, Lindgren, Arne, Wasselius, Johan, Drake, Mattias, Stenman, Martin, Ilinca, Andreea, Staals, Julie, Sadr-Nabavi, Ariane, Crawford, Katherine, Lena, Umme, Mateen, Farrah, Ay, Hakan, Wu, Ona, Schirmer, Markus, Romero, Javier, Cramer, Steve, Golland, Polina, Mueller, Bertram, Brown, Robert, Meschia, James, Ross, Owen A., Pare, Guillaume, Chong, Mike, mansour, Ossama yassin, Karaszewski, Bartosz, Enzinger, Christian, Schmidt, Reinhold, Seiler, Stephan, Pichler, Alexander, Ovbiagele, Bruce, Yamada, Yoshiji, Rundek, Tatjana, Blanton, Susan, P, John, Chern, Joseph, O'Donnell, Chris, Corriveau, Roderick, Bhattacharya, Pallab, Gwinn, Katrina, CHANDRA, BHARATENDU, Chen, Christopher, Kalaria, Raj, Koenig, Jim, Singh, Om Prakash, Olugbodi, Akintomi, Giralt, Eva, Saleheen, Danish, de Leeuw, Frank-Erik, Klijn, Karin, Olesen, Jes, Kubo, Michiaki, Spence, David, Pedersen, Annie, Olsson, Maja, Martín, Juan José, Braga, Gabriel, Xu, Huichun, Assimes, Tim, Raskurazhev, Anton, Lee, Wei Ling, Burri, Philippe, Frid, Petrea, GmbH, Heilbronn, Deng, Zhen, Habibi-koolaee, Mahdi, Vijayan, Murali, Leung, Thomas, Wong, Lawrence, Mok, Vincent, Choy, Richard, Jern, Christina, Lebedeva, Elena, Farrall, Martin, Jiayuan, Xu, Loo, Keat Wei, Rinkel, Gabriel, Magnus, Rudolf, Goncalves, Anderson, Franca, Paulo, Cendes, Iscia, Carrera, Caty, Fernandez-Cadenas, Israel, Kim, Helen, Rolfs, Arndt, Owolabi, Mayowa, Bakker, Mark, Ruigrok, Ynte, Hauer, Allard, Pulit, Sara L., Algra, Ale, van der Laan, Sander W., Macleod, Mary, Howard, George, Tiwari, Hemant, Irvin, Ryan, Albright, Karen C., Perry, Rodney, Kidwell, Chelsea, Pavlovic, Aleksandra, Sargurupremraj, Murali, Schilling, Sabrina, Pezzini, Alessandro, Abd-Allah, Foad, DeCarli, Charles, Liebeskind, David, Traylor, Matthew, Tan, Rhea, Danesh, John, Larsson, Susanna C., Rutten, Loes, Donatti, Amanda, Avelar, Wagner, Broderick, Joseph, Woo, Daniel, Kissela, Brett, Ibenez, Laura Garcia, Salman, Rustam, Sudlow, Cathie, McDonough, Caitrin Wheeler, Silliman, Scott, Magvanjav, Oyunbileg, van Agtmael, Tom, Walters, Matthew, Lorentzen, Erik, Stanne, Tara, Olsson, Martina, Nakagawa, Kazuma, Akinyemi, Rufus, Cotlatciuc, Ioana, O'Connell, Jeff, Sparks, Mary, Sorkin, John, Dave, Tushar, Naylor, Jill, Brown, Devin, Du, Rose, Kulik, Tobias B., Attia, John, Faber, James E, Rothwell, Peter, Márquez, Elsa Valdés, Mancuso, Michelangelo, Souza, Doralina Brum, de Silva, Ranil, Vibo, Riina, Korv, Janika, Maguire, Jane, Fornage, Myriam, Illoh, Kachikwu, Milewicz, Dianna, Majersik, Jennifer, DeHavenon, Adam, Kalani, Yashar, Alexander, Matthew, Cushman, Mary, Sale, Michele, Owens, Debra, Keene, Keith, Rich, Stephe, Psaty, Bruce, Longstreth, Will, Atadzhanov, Masharip, Wolfe, Stacey Quintero, Langefeld, Carl, Bushnell, Cheryl, Cruchaga, Carlos, Konrad, Jan, Liu, Junfeng, Sheth, Kevin, Falcone, Guido, Donahue J, Kathleen, Jones, Gregory T., Bown, Matthew J., Ko, Nerissa U., Coleman, Jonathan R.I., Breen, Gerome, Zaroff, Jonathan G., Klijn, Catharina J.M., Sargurupremraj, Muralidharan, Amouyel, Philippe, Debette, Stéphanie, Rinkel, Gabriel J.E., Worrall, Bradford B., Slowik, Agnieszka, Gaál-Paavola, Emilia I., Niemelä, Mika, Jääskeläinen, Juha E., von Und Zu Fraunberg, Mikael, Lindgren, Antti, Broderick, Joseph P., Werring, David J., Redon, Richard, Veldink, Jan H., Ruigrok, Ynte M., Stroke, HUNT All-In, Group, China Kadoorie Biobank Collaborative, Consortium, BioBank Japan Project, Group, ICAN Study, Group, CADISP, investigators, Genetics and Observational Subarachnoid Haemorrhage (GOSH) Study, (ISGC), International Stroke Genetics Consortium, Morel, Sandrine, and Bijlenga, Philippe Alexandre Pierre

Subjects
genetics [Blood Pressure], Medizin, Genome-wide association study, Blood Pressure, Disease, ddc:616.07, Bioinformatics, 616: Innere Medizin und Krankheiten, 0302 clinical medicine, Risk Factors, physiopathology [Hypertension], genetics [Genetic Predisposition to Disease], Genetic risk factor, Stroke, 0303 health sciences, Smoking, genetics [Smoking], genetics [Intracranial Aneurysm], Disorders of movement Donders Center for Medical Neuroscience [Radboudumc 3], Cerebrovascular disorder, 3. Good health, genetics [European Continental Ancestry Group], Hypertension, genetics [Polymorphism, Single Nucleotide], Subarachnoid hemorrhage, pathology [Intracranial Aneurysm], genetics [White People], Biology, Genetic correlation, pathology [Endothelial Cells], Polymorphism, Single Nucleotide, Article, White People, 03 medical and health sciences, Aneurysm, Asian People, ddc:570, Genetics, medicine, Humans, Genetic Predisposition to Disease, cardiovascular diseases, 030304 developmental biology, genetics [Subarachnoid Hemorrhage], genetics [Asian Continental Ancestry Group], 572: Biochemie, genetics [Asian People], pathology [Subarachnoid Hemorrhage], adverse effects [Smoking], Endothelial Cells, Subarachnoid Hemorrhage, medicine.disease, Intracranial aneurysm, Genetic architecture, ddc:616.8, Case-Control Studies, genetics [Hypertension], 030217 neurology & neurosurgery, Genome-Wide Association Study
Abstract

An author correction to this article published in December 2020 is available at https://doi.org/10.1038/s41588-020-00760-4. Rupture of an intracranial aneurysm leads to subarachnoid hemorrhage, a severe type of stroke. To discover new risk loci and the genetic architecture of intracranial aneurysms, we performed a cross-ancestry, genome-wide association study in 10,754 cases and 306,882 controls of European and East Asian ancestry. We discovered 17 risk loci, 11 of which are new. We reveal a polygenic architecture and explain over half of the disease heritability. We show a high genetic correlation between ruptured and unruptured intracranial aneurysms. We also find a suggestive role for endothelial cells by using gene mapping and heritability enrichment. Drug-target enrichment shows pleiotropy between intracranial aneurysms and antiepileptic and sex hormone drugs, providing insights into intracranial aneurysm pathophysiology. Finally, genetic risks for smoking and high blood pressure, the two main clinical risk factors, play important roles in intracranial aneurysm risk, and drive most of the genetic correlation between intracranial aneurysms and other cerebrovascular traits.

Published
2021
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130. Association of heart rate and diabetes among 0.5 million adults in the China Kadoorie biobank: Results from observational and Mendelian randomization analyses

Author

Wang, Wenxiu, primary, Wang, Jingjia, additional, Lv, Jun, additional, Yu, Canqing, additional, Shao, Chunli, additional, Tang, Yida, additional, Guo, Yu, additional, Bian, Zheng, additional, Du, Huaidong, additional, Yang, Ling, additional, Millwood, Iona Y., additional, Walters, Robin G., additional, Chen, Yiping, additional, Chang, Liang, additional, Fan, Lei, additional, Chen, Junshi, additional, Chen, Zhengming, additional, Huang, Tao, additional, Li, Liming, additional, Clarke, Robert, additional, Collins, Rory, additional, Peto, Richard, additional, Walters, Robin, additional, Avery, Daniel, additional, Boxall, Ruth, additional, Bennett, Derrick, additional, Chang, Yumei, additional, Gilbert, Simon, additional, Hacker, Alex, additional, Hill, Mike, additional, Holmes, Michael, additional, Iona, Andri, additional, Kartsonaki, Christiana, additional, Kerosi, Rene, additional, Kong, Ling, additional, Kurmi, Om, additional, Lancaster, Garry, additional, Lewington, Sarah, additional, Lin, Kuang, additional, McDonnell, John, additional, Millwood, Iona, additional, Nie, Qunhua, additional, Radhakrishnan, Jayakrishnan, additional, Ryder, Paul, additional, Sansome, Sam, additional, Schmidt, Dan, additional, Sherliker, Paul, additional, Sohoni, Rajani, additional, Stevens, Becky, additional, Turnbull, Iain, additional, Wang, Jenny, additional, Wang, Lin, additional, Wright, Neil, additional, Yang, Xiaoming, additional, Han, Xiao, additional, Hou, Can, additional, Pei, Pei, additional, Liu, Chao, additional, Tan, Yunlong, additional, Pang, Zengchang, additional, Gao, Ruqin, additional, Li, Shanpeng, additional, Wang, Shaojie, additional, Liu, Yongmei, additional, Du, Ranran, additional, Zang, Yajing, additional, Cheng, Liang, additional, Tian, Xiaocao, additional, Zhang, Hua, additional, Zhai, Yaoming, additional, Ning, Feng, additional, Sun, Xiaohui, additional, Li, Feifei, additional, Lv, Silu, additional, Wang, Junzheng, additional, Hou, Wei, additional, Zeng, Mingyuan, additional, Jiang, Ge, additional, Zhou, Xue, additional, Yang, Liqiu, additional, He, Hui, additional, Yu, Bo, additional, Li, Yanjie, additional, Xu, Qinai, additional, Kang, Quan, additional, Guo, Ziyan, additional, Wang, Dan, additional, Hu, Ximin, additional, Chen, Jinyan, additional, Fu, Yan, additional, Fu, Zhenwang, additional, Wang, Xiaohuan, additional, Weng, Min, additional, Guo, Zhendong, additional, Wu, Shukuan, additional, Li, Yilei, additional, Li, Huimei, additional, Fu, Zhifang, additional, Wu, Ming, additional, Zhou, Yonglin, additional, Zhou, Jinyi, additional, Tao, Ran, additional, Yang, Jie, additional, Su, Jian, additional, liu, Fang, additional, Zhang, Jun, additional, Hu, Yihe, additional, Lu, Yan, additional, Ma, Liangcai, additional, Tang, Aiyu, additional, Zhang, Shuo, additional, Jin, Jianrong, additional, Liu, Jingchao, additional, Tang, Zhenzhu, additional, Chen, Naying, additional, Huang, Ying, additional, Li, Mingqiang, additional, Meng, Jinhuai, additional, Pan, Rong, additional, Jiang, Qilian, additional, Lan, Jian, additional, Liu, Yun, additional, Wei, Liuping, additional, Zhou, Liyuan, additional, Ping Wang, Ningyu Chen, additional, Meng, Fanwen, additional, Qin, Yulu, additional, Wang, Sisi, additional, Wu, Xianping, additional, Zhang, Ningmei, additional, Chen, Xiaofang, additional, Zhou, Weiwei, additional, Luo, Guojin, additional, Li, Jianguo, additional, Zhong, Xunfu, additional, Liu, Jiaqiu, additional, Sun, Qiang, additional, Ge, Pengfei, additional, Ren, Xiaolan, additional, Dong, Caixia, additional, Zhang, Hui, additional, Mao, Enke, additional, Wang, Xiaoping, additional, Wang, Tao, additional, zhang, Xi, additional, Zhang, Ding, additional, Zhou, Gang, additional, Feng, Shixian, additional, Gao, Yulian, additional, He, Tianyou, additional, Sun, Huarong, additional, He, Pan, additional, Hu, Chen, additional, Zhang, Xukui, additional, Wu, Huifang, additional, Yu, Min, additional, Hu, Ruying, additional, Wang, Hao, additional, Qian, Yijian, additional, Wang, Chunmei, additional, Xie, Kaixu, additional, Chen, Lingli, additional, Zhang, Yidan, additional, Pan, Dongxia, additional, Gu, Qijun, additional, Huang, Yuelong, additional, Chen, Biyun, additional, Yin, Li, additional, Liu, Huilin, additional, Fu, Zhongxi, additional, Xu, Qiaohua, additional, Xu, Xin, additional, Zhang, Hao, additional, Long, Huajun, additional, Li, Xianzhi, additional, Zhang, Libo, additional, and Qiu, Zhe, additional

Published
2021
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131. Standardizing nomenclature in regional anesthesia: an ASRA-ESRA Delphi consensus study of abdominal wall, paraspinal, and chest wall blocks

Author

El-Boghdadly, Kariem, primary, Wolmarans, Morné, additional, Stengel, Angela D, additional, Albrecht, Eric, additional, Chin, Ki Jinn, additional, Elsharkawy, Hesham, additional, Kopp, Sandra, additional, Mariano, Edward R, additional, Xu, Jeff L, additional, Adhikary, Sanjib, additional, Altıparmak, Başak, additional, Barrington, Michael J, additional, Bloc, Sébastien, additional, Blanco, Rafael, additional, Boretsky, Karen, additional, Børglum, Jens, additional, Breebaart, Margaretha, additional, Burckett-St Laurent, David, additional, Capdevila, Xavier, additional, Carvalho, Brendan, additional, Chuan, Alwin, additional, Coppens, Steve, additional, Costache, Ioana, additional, Dam, Mette, additional, Egeler, Christian, additional, Fajardo, Mario, additional, Gadsden, Jeff, additional, Gautier, Philippe Emmanuel, additional, Grant, Stuart Alan, additional, Hadzic, Admir, additional, Hebbard, Peter, additional, Hernandez, Nadia, additional, Hogg, Rosemary, additional, Holtz, Margaret, additional, Johnson, Rebecca L, additional, Karmakar, Manoj Kumar, additional, Kessler, Paul, additional, Kwofie, Kwesi, additional, Lobo, Clara, additional, Ludwin, Danielle, additional, MacFarlane, Alan, additional, McDonnell, John, additional, McLeod, Graeme, additional, Merjavy, Peter, additional, Moran, EML, additional, O'Donnell, Brian D, additional, Parras, Teresa, additional, Pawa, Amit, additional, Perlas, Anahi, additional, Rojas Gomez, Maria Fernanda, additional, Sala-Blanch, Xavier, additional, Saporito, Andrea, additional, Sinha, Sanjay Kumar, additional, Soffin, Ellen M, additional, Thottungal, Athmaja, additional, Tsui, Ban C H, additional, Tulgar, Serkan, additional, Turbitt, Lloyd, additional, Uppal, Vishal, additional, van Geffen, Geert J, additional, Volk, Thomas, additional, and Elkassabany, Nabil M, additional

Published
2021
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134. Standardizing nomenclature in regional anesthesia:An ASRA-ESRA Delphi consensus study of abdominal wall, paraspinal, and chest wall blocks

Author

El-Boghdadly, Kariem, Wolmarans, Morné, Stengel, Angela D., Albrecht, Eric, Chin, Ki Jinn, Elsharkawy, Hesham, Kopp, Sandra, Mariano, Edward R., Xu, Jeff L., Adhikary, Sanjib, Altlparmak, Başak, Barrington, Michael J., Bloc, Sébastien, Blanco, Rafael, Boretsky, Karen, Børglum, Jens, Breebaart, Margaretha, Laurent, David Burckett St, Capdevila, Xavier, Carvalho, Brendan, Chuan, Alwin, Coppens, Steve, Costache, Ioana, Dam, Mette, Egeler, Christian, Fajardo, Mario, Gadsden, Jeff, Gautier, Philippe Emmanuel, Grant, Stuart Alan, Hadzic, Admir, Hebbard, Peter, Hernandez, Nadia, Hogg, Rosemary, Holtz, Margaret, Johnson, Rebecca L., Karmakar, Manoj Kumar, Kessler, Paul, Kwofie, Kwesi, Lobo, Clara, Ludwin, Danielle, MacFarlane, Alan, McDonnell, John, McLeod, Graeme, Merjavy, Peter, Moran, E. M.L., O'Donnell, Brian D., Parras, Teresa, Pawa, Amit, Perlas, Anahi, Rojas Gomez, Maria Fernanda, Sala-Blanch, Xavier, Saporito, Andrea, Sinha, Sanjay Kumar, Soffin, Ellen M., Thottungal, Athmaja, Tsui, Ban C.H., Tulgar, Serkan, Turbitt, Lloyd, Uppal, Vishal, Van Geffen, Geert J., Volk, Thomas, Elkassabany, Nabil M., El-Boghdadly, Kariem, Wolmarans, Morné, Stengel, Angela D., Albrecht, Eric, Chin, Ki Jinn, Elsharkawy, Hesham, Kopp, Sandra, Mariano, Edward R., Xu, Jeff L., Adhikary, Sanjib, Altlparmak, Başak, Barrington, Michael J., Bloc, Sébastien, Blanco, Rafael, Boretsky, Karen, Børglum, Jens, Breebaart, Margaretha, Laurent, David Burckett St, Capdevila, Xavier, Carvalho, Brendan, Chuan, Alwin, Coppens, Steve, Costache, Ioana, Dam, Mette, Egeler, Christian, Fajardo, Mario, Gadsden, Jeff, Gautier, Philippe Emmanuel, Grant, Stuart Alan, Hadzic, Admir, Hebbard, Peter, Hernandez, Nadia, Hogg, Rosemary, Holtz, Margaret, Johnson, Rebecca L., Karmakar, Manoj Kumar, Kessler, Paul, Kwofie, Kwesi, Lobo, Clara, Ludwin, Danielle, MacFarlane, Alan, McDonnell, John, McLeod, Graeme, Merjavy, Peter, Moran, E. M.L., O'Donnell, Brian D., Parras, Teresa, Pawa, Amit, Perlas, Anahi, Rojas Gomez, Maria Fernanda, Sala-Blanch, Xavier, Saporito, Andrea, Sinha, Sanjay Kumar, Soffin, Ellen M., Thottungal, Athmaja, Tsui, Ban C.H., Tulgar, Serkan, Turbitt, Lloyd, Uppal, Vishal, Van Geffen, Geert J., Volk, Thomas, and Elkassabany, Nabil M.

Abstract

Background There is heterogeneity in the names and anatomical descriptions of regional anesthetic techniques. This may have adverse consequences on education, research, and implementation into clinical practice. We aimed to produce standardized nomenclature for abdominal wall, paraspinal, and chest wall regional anesthetic techniques. Methods We conducted an international consensus study involving experts using a three-round Delphi method to produce a list of names and corresponding descriptions of anatomical targets. After long-list formulation by a Steering Committee, the first and second rounds involved anonymous electronic voting and commenting, with the third round involving a virtual round table discussion aiming to achieve consensus on items that had yet to achieve it. Novel names were presented where required for anatomical clarity and harmonization. Strong consensus was defined as ≥75% agreement and weak consensus as 50% to 74% agreement. Results Sixty expert Collaborators participated in this study. After three rounds and clarification, harmonization, and introduction of novel nomenclature, strong consensus was achieved for the names of 16 block names and weak consensus for four names. For anatomical descriptions, strong consensus was achieved for 19 blocks and weak consensus was achieved for one approach. Several areas requiring further research were identified. Conclusions Harmonization and standardization of nomenclature may improve education, research, and ultimately patient care. We present the first international consensus on nomenclature and anatomical descriptions of blocks of the abdominal wall, chest wall, and paraspinal blocks. We recommend using the consensus results in academic and clinical practice.

Published
2021

144. List of Contributors

Author

Alexiev, Vladimir, primary, Breslin, Dora, additional, Capdevila, Xavier, additional, Grant, Stewart, additional, Mannion, Stephen, additional, McAdoo, John, additional, McDonnell, John, additional, and O'Donnell, Brian, additional

Published
2011
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