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Primary squamous cell carcinoma (SCC) of the stomach is a very rare disease. However, the pathogenesis, clinical characteristics, and prognosis of gastric SCC are controversial and remain to be elucidated. Herein, we report a case of primary gastric SCC of the remnant stomach after subtotal gastrectomy. A 65-year-old man was admitted to our hospital due to epigastric discomfort and dizziness. He had undergone subtotal gastrectomy 40 years previously for gastric ulcer perforation. Endoscopy revealed a normal esophagus and a large mass in the remnant stomach. Abdominal computed tomography revealed enhanced wall thickening of the anastomotic site and suspected metachronous gastric cancer. Endoscopic biopsy revealed SCC. Total gastrectomy was performed with Roux-en-Y esophagojejunostomy. A 10-cm tumor was located at the remnant stomach just proximal to the previous area of anastomosis. Pathologic examination showed well-differentiated SCC extended into the subserosa without lymph node involvement (T3N0M0). The patient received adjuvant systemic chemotherapy with 6 cycles of 5-FU and cisplatin regimen, and he is still alive at the 54-month follow-up. According to the treatment principles of gastric cancer, early detection and radical surgical resection can improve the prognosis. [ABSTRACT FROM AUTHOR]

Background: Previously, cutaneous lymphomas were classified according to either the European Organization for the Research and Treatment of Cancer (EORTC) or the World Health Organization (WHO) classification paradigms. The aim of this study was to determine the relative frequency of Korean cutaneous lymphoma according to the new WHO-EORTC classification system. Methods: A total of 517 patients were recruited during a recent 5 year-period (2006-2010) from 21 institutes and classified according to the WHO-EORTC criteria. Results: The patients included 298 males and 219 females, and the mean age at diagnosis was 49 years. The lesions preferentially affected the trunk area (40.2%). The most frequent subtypes in order of decreasing prevalence were mycosis fungoides (22.2%), peripheral T-cell lymphoma (17.2%), CD30+ T-cell lymphoproliferative disorder (13.7%), and extranodal natural killer/T (NK/T) cell lymphoma, nasal type (12.0%). Diffuse large B-cell lymphoma accounted for 11.2% of cases, half of which were secondary cutaneous involvement; other types of B-cell lymphoma accounted for less than 1% of cases. Conclusions: In comparison with data from Western countries, this study revealed relatively lower rates of mycosis fungoides and B-cell lymphoma in Korean patients, as well as higher rates of subcutaneous panniculitis-like T-cell lymphoma and NK/T cell lymphoma. [ABSTRACT FROM AUTHOR]

Uterine rhabdomyosarcoma (RMS) typically presents as a mixed epithelial and mesenchymal tumors. Pure RMSs of the female genital tract are uncommon. Spindle cell variant of RMS is a rare morphologic subtype of embryonal RMS and mostly occurs in the paratesticular region of children. Here, we present a case of uterine spindle cell RMS in a 76-year-old woman. The tumor, 20×15×7 cm in size, was highly necrotic and adherent to the colon and rectum. Tumor cells were mostly spindle-shaped, and isolated rhabdomyoblasts were scattered. Immunohistochemical stains for myoglobin and myo-D1 showed diffuse positivity for tumor cells. The patient died only of disease three months after diagnosis. [ABSTRACT FROM AUTHOR]

The objective in current design practice for parking structures is that energy is dissipated through the formation of plastic hinges at the base of shear walls while floor diaphragms remain elastic and are vertically supported by a combination of shear walls and gravity resisting columns. Unfortunately, this objective is not always achieved due to inaccuracies in current methods for calculating demands on shear walls and in calculating the capacity of shear walls (IBC 2003, ACI code). When demands are overestimated and capacity underestimated, then diaphragm can fail prior to flexural yield of shear walls as was observed in several parking structures in the 1994 Northridge earthquake. Eigenvalue and inelastic dynamic response analyses were performed in order to investigate the effects of diaphragm flexibility on wall responses and of wall overstrength on diaphragm responses. The elongated periods of parking structures due to diaphragm flexibility were found to significantly decrease seismic force demand on shear walls relative to what is calculated using codes of practice in which diaphragms are assumed to be rigid. This leads to the over design of shear walls, which further compounds the problem by preventing the flexural yielding of these walls and thereby driving inelastic response to diaphragms. Various degrees of diaphragm flexibility, shear wall layout, seismic zone, and the number of stories were considered in these analyses. Inelastic static pushover analyses were preformed to investigate the design and capacity evaluation of shear walls. The results illustrate that the shear capacity of walls may be close to twice that calculated by codes of practice. The largest overstrengths were observed in shear walls with low height-to-length ratios in which a significant portion of the lateral load was taken by direct strut action to the foundation and without placing demands on the longitudinal tension reinforcement in the shear walls. The article concludes that methods in codes of practice for calculating shear wall demands and capacities need to be improved if good seismic performance of parking structures is to be achieved. [ABSTRACT FROM AUTHOR]

The article examines the efficiency of the multiple intradermal injections in treating patients with severe alopecia areata and widespread recalcitrant eczematous dermatitis. It suggests that each therapeutic session may require up to several hundred injections. Cautionary method is an important factor to consider in order to prevent bending the needle when inserting uncapped syringe fitted with a 30-gauge needle into the five milliliter syringe.

An abstract of the article "Design and Analysis of Heavily Loaded Reinforced Concrete Link Beams for Burj Dubai" by Ho Jung Lee, Daniel A. Kuchma, William Baker, and Lawrence C. Novak is presented.

Red pepper, one of the most important vegetable crops in Korea, is severely affected by viral diseases causing 20-50 % reduction in product yield. A pepper strain of tobacco mosaic virus (TMV-p) is the most common virus in red pepper. To study the molecular structure of the TMV -p virus, we generated cDNA clones of the viral genome. Partial sequencing of a few cDNA clones revealed that TMV-p shares a 98% identity at the nucleotide level with the Spanish isolate of pepper mild mottle virus (PMMV-s). This suggests that TMVp should be reclassified as the Korean isolate of PMMV (pMMV ok). The coat protein (CP) gene together with the 3' untranslated region of the PMMV-k virus was obtained by reverse transcriptase-polymerase chain reaction (RT -PCR) using oligomers deduced from the sequence of PMMV-s. The sequence analysis of the CP gene and the 3' untranslated region further confirmed that PMMV-k is highly related to PMMV-s. The CP gene and the 3' untranslated region of PMMV-k were cloned into a plant expression vector and the construct was introduced into tobacco plants. The transgenic plants expressing the PMMV-k CP gene were delayed in developing systemic disease or failed to develop symptoms at all after inoculation with PMMV ok. Delay of symptoms was also observed when the plants were inoculated with TMV-OM which shares a 74% homology with PMMV-k in the amino acid sequence of the CP region. In a local lesion host, the CP expressing plants exhibited a greatly reduced number of necrotic lesions as compared to control plants after inoculation with TMV-OM. Our results show that CP-mediated viral resistance is readily applicable in the case of PMMV -k and can provide resistance to other viruses in the tobamovirus group. [ABSTRACT FROM AUTHOR]