10,597 results on '"Haberl, A"'
Search Results
102. Unveiling patterns in human dominated landscapes through mapping the mass of US built structures
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Frantz, David, Schug, Franz, Wiedenhofer, Dominik, Baumgart, André, Virág, Doris, Cooper, Sam, Gómez-Medina, Camila, Lehmann, Fabian, Udelhoven, Thomas, van der Linden, Sebastian, Hostert, Patrick, and Haberl, Helmut
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- 2023
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103. Human cytomegalovirus seropositivity is associated with reduced patient survival during sepsis
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Unterberg, M., Ehrentraut, S. F., Bracht, T., Wolf, A., Haberl, H., von Busch, A., Rump, K., Ziehe, D., Bazzi, M., Thon, P., Sitek, B., Marcus, K., Bayer, M., Schork, K., Eisenacher, M., Ellger, B., Oswald, D., Wappler, F., Defosse, J., Henzler, D., Köhler, T., Zarbock, A., Putensen, C. P., Schewe, J. C., Frey, U. H., Anft, M., Babel, N., Steinmann, E., Brüggemann, Y., Trilling, M., Schlüter, A., Nowak, H., Adamzik, M., Rahmel, T., and Koos, B.
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- 2023
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104. Built structures influence patterns of energy demand and CO2 emissions across countries
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Haberl, Helmut, Löw, Markus, Perez-Laborda, Alejandro, Matej, Sarah, Plank, Barbara, Wiedenhofer, Dominik, Creutzig, Felix, Erb, Karl-Heinz, and Duro, Juan Antonio
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- 2023
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105. Advancing neutron diffraction for accurate structural measurement of light elements at megabar pressures
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Haberl, Bianca, Guthrie, Malcolm, and Boehler, Reinhard
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- 2023
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106. Exploring the relationship between HCMV serostatus and outcomes in COVID-19 sepsis
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Dominik Ziehe, Alexander Wolf, Tim Rahmel, Hartmuth Nowak, Helge Haberl, Lars Bergmann, Katharina Rump, Birte Dyck, Lars Palmowski, Britta Marko, Andrea Witowski, Katrin Maria Willemsen, Stephanie Pfaender, Martin Eisenacher, Moritz Anft, Nina Babel, Thilo Bracht, Barbara Sitek, Malte Bayer, Alexander Zarbock, Thilo von Groote, Christian Putensen, Stefan Felix Ehrentraut, Christina Weisheit, Michael Adamzik, Matthias Unterberg, and Björn Koos
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viral sepsis ,COVID-19 risk stratification ,human cytomegalovirus ,cross-reactive CD8+ T-cells ,COVID-19 survival ,Immunologic diseases. Allergy ,RC581-607 - Abstract
BackgroundSepsis, a life-threatening condition caused by the dysregulated host response to infection, is a major global health concern. Understanding the impact of viral or bacterial pathogens in sepsis is crucial for improving patient outcomes. This study aimed to investigate the human cytomegalovirus (HCMV) seropositivity as a risk factor for development of sepsis in patients with COVID-19.MethodsA multicenter observational study enrolled 95 intensive care patients with COVID-19-induced sepsis and 80 post-surgery individuals as controls. HCMV serostatus was determined using an ELISA test. Comprehensive clinical data, including demographics, comorbidities, and 30-day mortality, were collected. Statistical analyses evaluated the association between HCMV seropositivity and COVID-19 induced sepsis.ResultsThe prevalence of HCMV seropositivity did not significantly differ between COVID-19-induced sepsis patients (78%) and controls (71%, p = 0.382) in the entire cohort. However, among patients aged ≤60 years, HCMV seropositivity was significantly higher in COVID-19 sepsis patients compared to controls (86% vs 61%, respectively; p = 0.030). Nevertheless, HCMV serostatus did not affect 30-day survival.DiscussionThese findings confirm the association between HCMV seropositivity and COVID-19 sepsis in non-geriatric patients. However, the lack of an independent effect on 30-day survival can be explained by the cross-reactivity of HCMV specific CD8+ T-cells towards SARS-CoV-2 peptides, which might confer some protection to HCMV seropositive patients. The inclusion of a post-surgery control group strengthens the generalizability of the findings. Further research is needed to elucidate the underlying mechanisms of this association, explore different patient populations, and identify interventions for optimizing patient management.ConclusionThis study validates the association between HCMV seropositivity and severe COVID-19-induced sepsis in non-geriatric patients, contributing to the growing body of evidence on viral pathogens in sepsis. Although HCMV serostatus did not independently influence 30-day survival, future investigations should focus on unraveling the intricate interplay between HCMV, immune responses, and COVID-19. These insights will aid in risk stratification and the development of targeted interventions for viral sepsis.
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- 2024
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107. Human appropriation of net primary production (HANPP)
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Haberl, Helmut, primary, Erb, Karl-Heinz, additional, and Krausmann, Fridolin, additional
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- 2023
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108. Nexus approaches in socio-metabolic research
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Haberl, Helmut, primary
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- 2023
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109. eROSITA calibration and performance verification phase: High-mass X-ray binaries in the Magellanic Clouds
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Haberl, F., Maitra, C., Carpano, S., Dai, X., Doroshenko, V., Dennerl, K., Freyberg, M. J., Sasaki, M., Udalski, A., Postnov, K. A., and Shakura, N. I.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
During its performance verification phase, the soft X-ray instrument eROSITA aboard the Spektrum-Roentgen-Gamma(SRG) spacecraft observed large regions in the Magellanic Clouds, where almost 40 known high-mass X-ray binaries (HMXBs, including candidates) are located. We looked for new HMXBs in the eROSITA data, searched for pulsations in HMXB candidates and investigated the long-term behaviour of the full sample using archival X-ray and optical data. For sources sufficiently bright, a detailed spectral and temporal analysis of their eROSITA data was performed. A source detection analysis of the eROSITA images in different energy bands provided count rates and upper limits for the remaining sources. We report the discovery of a new Be/X-ray binary in the Large Magellanic Cloud. The transient SRGEt J052829.5-690345 was detected with a 0.2-8.0 keV luminosity of ~10^35 erg/s and exhibits a hard X-ray spectrum, typical for this class of HMXBs. The OGLE I-band light curve of the V~15.7 mag counterpart shows large variations by up to 0.75 mag, which occur quasi periodically with ~511 days. The eROSITA observations of the Small Magellanic Cloud covered 16 Be/X-ray binary pulsars, five of them were bright enough to accurately determine their current pulse period. The pulse periods for SXP 726 and SXP 1323 measured from eROSITA data are ~800 s and ~1006 s, respectively, far away from their discovery periods. Including archival XMM-Newton observations we update the spin-period history of the two long-period pulsars which show nearly linear trends in their period evolution since more than 15 years. The corresponding average spin-down rate for SXP 726 is 4.3 s/yr while SXP 1323 shows spin-up with a rate of -23.2 s/yr. We discuss the spin evolution of the two pulsars in the framework of quasi-spherical accretion., Comment: 21 pages, 28 figures, accepted for publication in Astronomy & Astrophysics, First science highlights from SRG/eROSITA
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- 2021
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110. Radio Continuum Sources behind the Large Magellanic Cloud
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Filipović, M. D., Bojičić, I. S., Grieve, K. R., Norris, R. P., Tothill, N. F. H., Shobhana, D., Rudnick, L., Prandoni, I., Andernach, H., Hurley-Walker, N., Alsaberi, R. Z. E., Anderson, C. S., Collier, J. D., Crawford, E. J., For, B. -Q., Galvin, T. J., Haberl, F., Hopkins, A. M., Ingallinera, A., Kavanagh, P. J., Koribalski, B. S., Kothes, R., Leahy, D., Leverenz, H., Maggi, P., Maitra, C., Marvil, J., Pannuti, T. G., Park, L. A. F., Payne, J. L., Pennock, C. M., Riggi, S., Rowell, G., Sano, H., Sasaki, M., Staveley-Smith, L., Trigilio, V., Umana, G., Urošević, D., van Loon, J. Th., and Vardoulaki, E.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We present a comprehensive multi-frequency catalogue of radio sources behind the Large Magellanic Cloud between 0.2 and 20 GHz, gathered from a combination of new and legacy radio continuum surveys. This catalogue covers an area of $\sim$144~deg$^2$ at angular resolutions from 45 arcsec to $\sim$3 arcmin. We find 6434 discrete radio sources in total, of which 3789 are detected at two or more radio frequencies. We estimate the median spectral index ($\alpha$; where $S_{v}\sim\nu^\alpha$) of $\alpha = -0.89 $ and mean of $-0.88 \pm 0.48$ for 3636 sources detected exclusively at two frequencies (0.843 and 1.384 GHz) with similar resolution (FWHM $\sim$40-45 arcsec). The large frequency range of the surveys makes it an effective tool to investigate Gigahertz Peak Spectrum (GPS), Compact Steep Spectrum (CSS) and Infrared Faint Radio sources populations within our sample. We find 10 GPS candidates with peak frequencies near 5 GHz, from which we estimate their linear size. 1866 sources from our catalogue are (CSS) candidates with $\alpha <-0.8$. We found six candidates for High Frequency Peaker (HFP) sources, whose radio fluxes peak above 5 GHz and no sources with unconstrained peaks and $\alpha~>0.5$. We found optical counterparts for 343 of the radio continuum sources, of which 128have a redshift measurement. Finally, we investigate the population of 123 Infrared Faint Radio Sources (IFRSs) found in this study., Comment: Accepted for publication in MNRAS
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- 2021
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111. SN 1987A : Tracing the flux decline and spectral evolution through a comparison of SRG/eROSITA and XMM-Newton observations
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Maitra, C., Haberl, F., Sasaki, M., Maggi, P., Dennerl, K., and Freyberg, M. J.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
SN 1987A is the closest observed supernova in the last four centuries and provides a unique opportunity to witness the birth and evolution of a supernova remnant. The source has been monitored by XMM Newton EPIC-pn from 2007--2020. SRG/eROSITA also observed the source during its commissioning phase and the first light in Sept. and Oct. 2019. We investigated the spectral and flux evolution of SN 1987A in X-rays over the last fourteen years up to Nov. 2020 using XMM-Newton and eROSITA observations. We performed a detailed spectral analysis using a three-component plane-parallel shock model and analysed and modelled the EPIC-pn monitoring and eROSITA observations in a consistent manner. This paper reports a complete and most up to date flux evolution of SN 1987A in the soft (0.5-2 keV) and hard (3-10 keV) X-ray band. The flux in the soft band flattened around 9424 d and then displayed a turnover between 10142-10493 d after which it showed a continued decline. Around the same time, a break in the hard-band flux time evolution slope was detected. This implies that the blast wave has now passed beyond the dense structures of the equatorial ring and is expanding further into more tenuous circumstellar medium. The temporal evolution of the normalizations of the three shock components match well the results of hydrodynamical simulations predicting a blue supergiant progenitor scenario. The trend at recent epochs indicate that the emission caused by the forward shock after leaving the equatorial ring and by the reverse shock in the ejecta is becoming more dominant now. The elemental abundances in the hot plasma component are significantly higher than those in the `cooler' one, indicating its origin from the reverse shock propagating into the ejecta., Comment: 11 pages, 7 figures, 7 tables, Accepted in A&A for the Special Issue: The Early Data Release of eROSITA and Mikhail Pavlinsky ART-XC on the SRG Mission
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- 2021
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112. SRGA J124404.1-632232/SRGU J124403.8-632231: a new X-ray pulsar discovered in the all-sky survey by SRG
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Doroshenko, V., Staubert, R., Maitra, C., Rau, A., Haberl, F., Santangelo, A., Schwope, A., Wilms, J., Buckley, D. A. H., Semena, A., Mereminskiy, I., Lutovinov, A., Gromadzki, M., Townsend, L. J., and Monageng, I. M.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Ongoing all-sky surveys by the the eROSITA and the Mikhail Pavlinsky ART-XC telescopes on-board the Spectrum Roentgen Gamma (SRG) mission have already revealed over a million of X-ray sources. One of them, SRGA J124404.1-632232/SRGU J124403.8-632231, was detected as a new source in the third (of the planned eight) consecutive X-ray surveys by ART-XC. Based on the properties of the identified optical counterpart it was classified as a candidate X-ray binary (XRB). We report on the follow-up observations of this source with Nuclear Spectroscopic Telescope Array (NuSTAR), Neil Gehrels Swift Observatory (Swift), and the Southern African Large Telescope (SALT), which allowed us to unambiguously confirm the initial identification and establish SRGU J124403.8-632231 as a new X-ray pulsar with a spin period of ~538 s and a Be-star companion, making it one of the first Galactic X-ray pulsars discovered by SRG., Comment: Submitted to A&A for the Special Issue: The Early Data Release of eROSITA and Mikhail Pavlinsky ART-XC on the SRG Mission
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- 2021
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113. SRG/eROSITA discovery of 164 s pulsations from the SMC Be/X-ray binary XMMU J010429.4-723136
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Carpano, S., Haberl, F., Maitra, C., Freyberg, M., Dennerl, K., Schwope, A., Buckley, A. H., and Monageng, I. M.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Context. The Small Magellanic Cloud (SMC) hosts many known high-mass X-ray binaries (HMXBs), and all but one (SMC X-1) have a Be companion star. Through the calibration and verification phase of eROSITA on board the Spektrum-Roentgen-Gamma (SRG) spacecraft, the Be/X-ray binary XMMU J010429.4-723136 was in the field of view during observations of the supernova remnant, 1E0102.2-7219, used as a calibration standard. Aims. We report timing and spectral analyses of XMMU J010429.4-723136 based on three eROSITA observations of the field, two of which were performed on 2019 November 7-9, with the third on 2020 June 18-19. We also reanalyse the OGLE-IV light curve for that source in order to determine the orbital period. Methods. We performed a Lomb-Scargle periodogram analysis to search for pulsations (from the X-ray data) and for the orbital period (from the OGLE data). X-ray spectral parameters and fluxes were retrieved from the best-fit model. Results. We detect, for the first time, the pulsations of XMMU J010429.4-723136 at a period of ~164 s, and therefore designate the source as SXP 164. From the spectral fitting, we derive a source flux of ~1x10e-12 erg s-1 cm-2 for all three observations, corresponding to a luminosity of ~4x10e35 erg s-1 at the distance of the SMC. Furthermore, reanalysing the OGLE light curve, including the latest observations, we find a significant periodic signal that we believe is likely be the orbital period; at 22.3d, this is shorter than the previously reported values. The Swift/XRT light curve, extracted from two long monitorings of the field and folded at the same period, suggests that a modulation is also present in the X-ray data., Comment: "To appear on A&A, Special Issue: The Early Data Release of eROSITA and Mikhail Pavlinsky ART-XC on the SRG Mission" 7 pages, 11 figures
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- 2021
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114. eROSITA detection of flares from the Be/X-ray binary A0538-66
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Ducci, L., Mereghetti, S., Santangelo, A., Ji, L., Carpano, S., Covino, S., Doroshenko, V., Haberl, F., Maitra, C., Kreykenbohm, I., and Udalski, A.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
In 2018, XMM-Newton observed the awakening in X-rays of the Be/X-ray binary (Be/XRB) A0538-66. It showed bright and fast flares close to periastron with properties that had never been observed in other Be/XRBs before. We report the results from the observations of A0538-66 collected during the first all-sky survey of eROSITA, an X-ray telescope (0.2-10 keV) on board the Spektrum-Roentgen-Gamma (SRG) satellite. eROSITA caught two flares within one orbital cycle at orbital phases $\phi = 0.29$ and $\phi = 0.93$ (where $\phi=0$ corresponds to periastron), with peak luminosities of $\sim 2-4 \times 10^{36}$ erg/s (0.2-10 keV) and durations of $42 \leq \Delta t_{\rm fl} \leq 5.7\times 10^4$ s. The flare observed at $\phi \approx 0.29$ shows that the neutron star can accrete considerably far from periastron, although it is expected to be outside of the circumstellar disk, thus providing important new information about the plasma environment surrounding the binary system. We also report the results from the photometric monitoring of A0538-66 carried out with the REM, OGLE, and MACHO telescopes from January 1993 until March 2020. We found that the two sharp peaks that characterize the orbital modulation in the optical occur asymmetrically in the orbit, relative to the position of the donor star., Comment: To appear on A&A, Special Issue: The Early Data Release of eROSITA and Mikhail Pavlinsky ART-XC on the SRG Mission
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- 2021
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115. The eROSITA Final Equatorial-Depth Survey (eFEDS): Presenting The Demographics of X-ray Emission From Normal Galaxies
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Vulic, N., Hornschemeier, A. E., Haberl, F., Basu-Zych, A. R., Kyritsis, E., Zezas, A., Salvato, M., Ptak, A., Bogdan, A., Kovlakas, K., Wilms, J., Sasaki, M., Liu, T., Merloni, A., Dwelly, T., Brunner, H., Lamer, G., Maitra, C., Nandra, K., and Santangelo, A.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
The $\it{eROSITA}$ Final Equatorial Depth Survey (eFEDS), completed during the calibration and performance verification phase of the $\it{eROSITA}$ instrument on $\it{Spectrum\, Roentgen\, Gamma}$, delivers data at and beyond the final depth of the four-year $\it{eROSITA}$ all-sky survey (eRASS:8), $f_{0.5-2\,\text{ keV}}$ = $1.1\times10^{-14}$ erg s$^{-1}$ cm$^{2}$, over 140 deg$^{2}$. It provides the first view of normal galaxy X-ray emission from X-ray binaries (XRBs) and the hot interstellar medium at the full depth of eRASS:8. We use the Heraklion Extragalactic Catalogue (HECATE) of galaxies to correlate with eFEDS X-ray sources and identify 94 X-ray detected normal galaxies. We classify galaxies as star-forming, early-type, composite, and AGN using SDSS and 6dF optical spectroscopy. The eFEDS field harbours 37 normal galaxies: 36 late-type (star-forming) galaxies and 1 early-type galaxy. There are 1.9 times as many normal galaxies as predicted by scaling relations via SIXTE simulations, with an overabundance of late-type galaxies and a dearth of early-type galaxies. Dwarf galaxies with high specific star formation rate (SFR) have elevated L$_{\text{X}}$/SFR when compared with specific SFR and metallicity, indicating an increase in XRB emission due to low-metallicity. We expect that eRASS:8 will detect 12,500 normal galaxies, the majority of which will be star-forming, with the caveat that there are unclassified sources in eFEDS and galaxy catalogue incompleteness issues that could increase the actual number of detected galaxies over these current estimates. eFEDS observations detected a rare population of galaxies -- the metal-poor dwarf starbursts -- that do not follow known scaling relations. eRASS is expected to discover significant numbers of these high-redshift analogues, which are important for studying the heating of the intergalactic medium at high-redshift., Comment: 17 pages, 10 figures, 3 tables. Submitted to A&A for the Special Issue: The Early Data Release of eROSITA and Mikhail Pavlinsky ART-XC on the SRG Mission
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- 2021
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116. Phase-resolved X-ray spectroscopy of PSR B0656+14 with SRG/eROSITA and XMM-Newton
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Schwope, Axel, Pires, Adriana M., Kurpas, Jan, Doroshenko, Victor, Suleimanov, Valery F., Freyberg, Michael, Becker, Werner, Dennerl, Konrad, Haberl, Frank, Lamer, Georg, Maitra, Chandreyee, Potekhin, Alexander Y., Ramos-Ceja, Miriam E., Santangelo, Andrea, Traulsen, Iris, and Werner, Klaus
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Solar and Stellar Astrophysics - Abstract
(abridged version) We present a detailed spectroscopic and timing analysis of X-ray observations of the bright radio-to-gamma-ray emitting pulsar PSR B0656+14, which were obtained simultaneously with eROSITA and XMM-Newton during the Calibration and Performance Verification phase of the Spektrum-Roentgen-Gamma mission (SRG) for 100 ks. Using XMM-Newton and NICER we firstly established an X-ray ephemeris for the time interval 2015 to 2020, which connects all X-ray observations in this period without cycle count alias and phase shifts. The mean eROSITA spectrum clearly reveals an absorption feature originating from the star at 570 eV with a Gaussian sigma of about 70 eV, tentatively identified earlier in a long XMM-Newton observation (Arumugasamy et al. 2018). A second absorption feature, described here as an absorption edge, occurs at 260-265 eV. It could be of atmospheric or of instrumental origin. These absorption features are superposed on various emission components, phenomenologically described as the sum of hot (120 eV) and cold (65 eV) blackbody components, both of photospheric origin, and a power-law with photon index Gamma=2. The phase-resolved spectroscopy reveals that the Gaussian absorption line at 570 eV is clearly present throughout ~60% of the spin cycle. The visibility of the line strength coincides in phase with the maximum flux of the hot blackbody. We also present three families of model atmospheres: a magnetised atmosphere, a condensed surface, and a mixed model, which were applied to the mean observed spectrum and whose continuum fit the observed data well. The atmosphere model, however, predicts too short distances. For the mixed model, the Gaussian absorption may be interpreted as proton cyclotron absorption in a field as high as 10^14 G, which is significantly higher than that derived from the moderate observed spin-down., Comment: Submitted to A&A for the Special Issue: The Early Data Release of eROSITA and Mikhail Pavlinsky ART-XC on the SRG Mission. 21 pages, 13 figures, 13 tables
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- 2021
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117. First studies of the diffuse X-ray emission in the Large Magellanic Cloud with eROSITA
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Sasaki, Manami, Knies, Jonathan, Haberl, Frank, Maitra, Chandreyee, Kerp, Jürgen, Bykov, Andrei M., Dennerl, Konrad, Filipović, Miroslav D., Freyberg, Michael, Koribalski, Bärbel S., Points, Sean, and Staveley-Smith, Lister
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
In the first months after the launch in July 2019, eROSITA onboard Spektr-RG (SRG) performed long-exposure observations in the regions around SN 1987A and SNR N132D in the Large Magellanic Cloud (LMC). We analyse the distribution and the spectrum of the diffuse X-ray emission in the observed fields to determine the physical properties of the hot phase of the interstellar medium (ISM). The eROSITA data are complemented by newly derived column density maps for the Milky Way and the LMC, 888 MHz radio continuum map from the Australian Square Kilometer Array Pathfinder (ASKAP), and optical images of the Magellanic Cloud Emission Line Survey (MCELS). We detect significant emission from thermal plasma with kT=0.2 keV in all the regions. There is also an additional higher-temperature emission component from a plasma with kT = 0.7 keV. In addition, non-thermal X-ray emission is significantly detected in the superbubble 30 Dor C. The absorbing column density NH in the LMC derived from the analysis of the X-ray spectra taken with eROSITA is consistent with the NH obtained from the emission of the cold medium over the entire area. Neon abundance is enhanced in the regions in and around 30 Dor and SN 1987A, indicating that the ISM has been chemically enriched by the young stellar population. Emission from the stellar cluster RMC 136 and the Wolf-Rayet stars RMC 139 and RMC 140 is best modelled with a high-temperature (kT>1 keV) non-equilibrium ionisation plasma emission and a non-thermal component with a photon index of {\Gamma} =1.3. In addition, the optical SNR candidate J0529-7004 is also detected with eROSITA and we thus confirm the source as an SNR., Comment: Submitted to A&A for the Special Issue: The Early Data Release of eROSITA and Mikhail Pavlinsky ART-XC on the SRG Mission
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- 2021
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118. The eROSITA Final Equatorial Depth Survey (eFEDS): The X-ray catalog
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Brunner, H., Liu, T., Lamer, G., Georgakakis, A., Merloni, A., Brusa, M., Bulbul, E., Dennerl, K., Friedrich, S., Liu, A., Maitra, C., Nandra, K., Ramos-Ceja, M. E., Sanders, J. S., Stewart, I. M., Boller, T., Buchner, J., Clerc, N., Comparat, J., Dwelly, T., Eckert, D., Finoguenov, A., Freyberg, M., Ghirardini, V., Gueguen, A., Haberl, F., Kreykenbohm, I., Krumpe, M., Osterhage, S., Pacaud, F., Predehl, P., Reiprich, T. H., Robrade, J., Salvato, M., Santangelo, A., Schrabback, T., Schwope, A., and Wilms, J.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
Context. The eROSITA X-ray telescope on board the Spectrum-Roentgen-Gamma (SRG) observatory combines a large field of view and collecting area in the energy range $\sim$0.2 to $\sim$8.0 keV with the capability to perform uniform scanning observations of large sky areas. Aims. SRG/eROSITA performed scanning observations of the $\sim$140 square degrees eROSITA Final Equatorial Depth Survey (eFEDS) field as part of its performance verification phase. The observing time was chosen to slightly exceed the depth of equatorial fields after the completion of the eROSITA all-sky survey. We present a catalog of detected X-ray sources in the eFEDS field providing source positions and extent information, as well as fluxes in multiple energy bands and document a suite of tools and procedures developed for eROSITA data processing and analysis, validated and optimized by the eFEDS work. Methods. A multi-stage source detection procedure was optimized and calibrated by performing realistic simulations of the eROSITA eFEDS observations. We cross-matched the eROSITA eFEDS source catalog with previous XMM-ATLAS observations, confirming excellent agreement of the eROSITA and XMM-ATLAS source fluxes. Result. We present a primary catalog of 27910 X-ray sources, including 542 with significant spatial extent, detected in the 0.2-2.3 keV energy range with detection likelihoods $\ge 6$, corresponding to a (point source) flux limit of $\approx 6.5 \times 10^{-15}$ erg/cm$^2$/s in the 0.5-2.0 keV energy band (80% completeness). A supplementary catalog contains 4774 low-significance source candidates with detection likelihoods between 5 and 6. In addition, a hard band sample of 246 sources detected in the energy range 2.3-5.0 keV above a detection likelihood of 10 is provided. The dedicated data analysis software package, calibration database, and calibrated data products are described in an appendix., Comment: 25 pages, 15 figures, accepted, A&A Special Issue: The Early Data Release of eROSITA and Mikhail Pavlinsky ART-XC on the SRG Mission
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- 2021
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119. The ASKAP-EMU Early Science Project: 888 MHz Radio Continuum Survey of the Large Magellanic Cloud
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Pennock, Clara M., van Loon, Jacco Th., Filipovic, Miroslav D., Andernach, Heinz, Haberl, Frank, Kothes, Roland, Lenc, Emil, Rudnick, Lawrence, White, Sarah V., Agliozzo, Claudia, Antón, Sonia, Bojicic, Ivan, Bomans, Dominik J., Collier, Jordan D., Crawford, Evan J., Hopkins, Andrew M., Jeganathan, Kanapathippillai, Kavanagh, Patrick J., Koribalski, Bärbel S., Leahy, Denis, Maggi, Pierre, Maitra, Chandreyee, Marvil, Josh, Michałowski, Michał J., Norris, Ray P., Oliveira, Joana M., Payne, Jeffrey L., Sano, Hidetoshi, Sasaki, Manami, Staveley-Smith, Lister, and Vardoulaki, Eleni
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Astrophysics - Astrophysics of Galaxies - Abstract
We present an analysis of a new 120 deg$^{2}$ radio continuum image of the Large Magellanic Cloud (LMC) at 888 MHz with a bandwidth of 288 MHz and beam size of $13\rlap{.}^{\prime\prime}9\times12\rlap{.}^{\prime\prime}1$, from the Australian Square Kilometre Array Pathfinder (ASKAP) processed as part of the Evolutionary Map of the Universe (EMU) survey. The median Root Mean Squared noise is 58 $\mu$Jy beam$^{-1}$. We present a catalogue of 54,612 sources, divided over a GOLD list (30,866 sources) complete down to 0.5 mJy uniformly across the field, a SILVER list (22,080 sources) reaching down to $<$ 0.2 mJy and a BRONZE list (1,666 sources) of visually inspected sources in areas of high noise and/or near bright complex emission. We discuss detections of planetary nebulae and their radio luminosity function, young stellar objects showing a correlation between radio luminosity and gas temperature, novae and X-ray binaries in the LMC, and active stars in the Galactic foreground that may become a significant population below this flux level. We present examples of diffuse emission in the LMC (H II regions, supernova remnants, bubbles) and distant galaxies showcasing spectacular interaction between jets and intracluster medium. Among 14,333 infrared counterparts of the predominantly background radio source population we find that star-forming galaxies become more prominent below 3 mJy compared to active galactic nuclei. We combine the new 888 MHz data with archival Australia Telescope Compact Array data at 1.4 GHz to determine spectral indices; the vast majority display synchrotron emission but flatter spectra occur too. We argue that the most extreme spectral index values are due to variability., Comment: Accepted for publication in MNRAS
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- 2021
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120. NICER Timing of the X-Ray Thermal Isolated Neutron Star RX J0806.4–4123
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B. Posselt, G. G. Pavlov, W. C. G. Ho, and F. Haberl
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- 2024
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121. Feasibility, Safety, and Technical Success of the Flying Intervention Team in Acute Ischemic Stroke: Comparison of Interventions in Different Primary Stroke Centers with those in a Comprehensive Stroke Center
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Kettner, Alexander, Schlachetzki, Felix, Boeckh-Behrens, Tobias, Zimmer, Claus, Wunderlich, Silke, Kraus, Frank, Haberl, Roman Ludwig, Hubert, Gordian Jan, Boy, Sandra, Henninger, Julia, Friedrich, Benjamin, and Maegerlein, Christian
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- 2023
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122. Role of Nuclear Imaging in Cardiac Stereotactic Body Radiotherapy for Ablation of Ventricular Tachycardia
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Haberl, Connor, Crean, Andrew M., Zelt, Jason G.E., Redpath, Calum J., and deKemp, Robert A.
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- 2024
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123. Advanced manufacturing of 3D custom boron-carbide collimators designed for complex environments for neutron scattering
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Islam, Fahima, Granroth, Garrett E., Molaison, Jamie J., Goldsby, Desarae, Siddel, Derek, Anderson, David C., Elliott, Amelia M., and Haberl, Bianca
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- 2024
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124. Diagnosis and prognosis of abnormal cardiac scintigraphy uptake suggestive of cardiac amyloidosis using artificial intelligence: a retrospective, international, multicentre, cross-tracer development and validation study
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Spielvogel, Clemens P, Haberl, David, Mascherbauer, Katharina, Ning, Jing, Kluge, Kilian, Traub-Weidinger, Tatjana, Davies, Rhodri H, Pierce, Iain, Patel, Kush, Nakuz, Thomas, Göllner, Adelina, Amereller, Dominik, Starace, Maria, Monaci, Alice, Weber, Michael, Li, Xiang, Haug, Alexander R, Calabretta, Raffaella, Ma, Xiaowei, Zhao, Min, Mascherbauer, Julia, Kammerlander, Andreas, Hengstenberg, Christian, Menezes, Leon J, Sciagra, Roberto, Treibel, Thomas A, Hacker, Marcus, and Nitsche, Christian
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- 2024
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125. How experiments with superblocks in Vienna shape climate and health outcomes and interact with the urban planning regime
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Brenner, Anna-Katharina, Haas, Willi, Rudloff, Christian, Lorenz, Florian, Wieser, Georg, Haberl, Helmut, Wiedenhofer, Dominik, and Pichler, Melanie
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- 2024
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126. Take the aTrain. Introducing an interface for the Accessible Transcription of Interviews
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Haberl, Armin, Fleiß, Jürgen, Kowald, Dominik, and Thalmann, Stefan
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- 2024
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127. What drives densification and sprawl in cities? A spatially explicit assessment for Vienna, between 1984 and 2018
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Brenner, Anna-Katharina, Haas, Willi, Krüger, Tobias, Matej, Sarah, Haberl, Helmut, Schug, Franz, Wiedenhofer, Dominik, Behnisch, Martin, Jaeger, Jochen A.G., and Pichler, Melanie
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- 2024
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128. Household energy systems based on biomass: Tracing material flows from source to service in rural Ethiopia
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Grabher, Harald F., Erb, Karlheinz, Singh, Simron, and Haberl, Helmut
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- 2024
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129. IKT16: Discovery of a 22 ms energetic rotation-powered pulsar in the Small Magellanic Cloud
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Maitra, C., Esposito, P., Tiengo, A., Ballet, J., Haberl, F., Dai, S., Filipovic, M. D., and Pilia, M.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We report here on the discovery with XMM-Newton of pulsations at 22 ms from the central compact source associated with IKT16, a supernova remnant in the Small Magellanic Cloud (SMC). The measured spin period and spin period derivative correspond to 21.7661076(2) ms and $2.9(3)\times10^{-14}$ s,s$^{-1}$, respectively. Assuming standard spin-down by magnetic dipole radiation, the spin-down power corresponds to $1.1\times10^{38}$,erg,s$^{-1}$ implying a Crab-like pulsar. This makes it the most energetic pulsar discovered in the SMC so far and a close analogue of PSR J0537--6910, a Crab-like pulsar in the Large Magellanic Cloud. The characteristic age of the pulsar is 12 kyr. Having for the first time a period measure for this source, we also searched for the signal in archival data collected in radio with the Parkes telescope and in Gamma-rays with the Fermi/LAT, but no evidence for pulsation was found in these energy bands., Comment: 5 pages, 4 figures, 2 tables. Accepted for publication in MNRAS Letters
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- 2021
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130. The EXTraS Project: Exploring the X-ray transient and variable sky
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De Luca, A., Salvaterra, R., Belfiore, A., Carpano, S., D'Agostino, D., Haberl, F., Israel, G. L., Law-Green, D., Lisini, G., Marelli, M., Novara, G., Read, A. M., Rodriguez-Castillo, G., Rosen, S. R., Salvetti, D., Tiengo, A., Vianello, G., Watson, M. G., Delvaux, C., Dickens, T., Esposito, P., Greiner, J., Haemmerle, H., Kreikenbohm, A., Kreykenbohm, S., Oertel, M., Pizzocaro, D., Pye, J. P., Sandrelli, S., Stelzer, B., Wilms, J., and Zagaria, F.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
Temporal variability in flux and spectral shape is ubiquitous in the X-ray sky and carries crucial information about the nature and emission physics of the sources. The EPIC instrument on board the XMM-Newton observatory is the most powerful tool for studying variability even in faint sources. Each day, it collects a large amount of information about hundreds of new serendipitous sources, but the resulting huge (and growing) dataset is largely unexplored in the time domain. The project called Exploring the X-ray transient and variable sky (EXTraS) systematically extracted all temporal domain information in the XMM-Newton archive. This included a search and characterisation of variability, both periodic and aperiodic, in hundreds of thousands of sources spanning more than eight orders of magnitude in timescale and six orders of magnitude in flux, and a search for fast transients that were missed by standard image analysis. All results, products, and software tools have been released to the community in a public archive. A science gateway has also been implemented to allow users to run the EXTraS analysis remotely on recent XMM datasets. We give details on the new algorithms that were designed and implemented to perform all steps of EPIC data analysis, including data preparation, source and background modelling, generation of time series and power spectra, and search for and characterisation of different types of variabilities. We describe our results and products and give information about their basic statistical properties and advice on their usage. We also describe available online resources. The EXTraS database of results and its ancillary products is a rich resource for any kind of investigation in almost all fields of astrophysics. Algorithms and lessons learnt from our project are also a very useful reference for any current and future experiment in the time domain., Comment: 39 pages; accepted for publication in Astronomy & Astrophysics
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- 2021
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131. Multiwavelength analysis of the X-ray spur and southeast of the Large Magellanic Cloud
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Knies, J. R., Sasaki, M., Fukui, Y., Tsuge, K., Haberl, F., Points, S., Kavanagh, P. J., and Filipović, M. D.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
Aims: The giant HII region 30 Doradus (30 Dor) located in the eastern part of the Large Magellanic Cloud is one of the most active star-forming regions in the Local Group. Studies of HI data have revealed two large gas structures which must have collided with each other in the region around 30 Dor. In X-rays there is extended emission ($\sim 1$ kpc) south of 30 Dor called the X-ray spur, which appears to be anticorrelated with the HI gas. We study the properties of the hot interstellar medium (ISM) in the X-ray spur and investigate its origin including related interactions in the ISM. Methods: We analyzed new and archival XMM-Newton data of the X-ray spur and its surroundings to determine the properties of the hot diffuse plasma. We created detailed plasma property maps by utilizing the Voronoi tessellation algorithm. We also studied HI and CO data, as well as optical line emission data of H$\alpha$ and [SII], and compared them to the results of the X-ray spectral analysis. Results: We find evidence of two hot plasma components with temperatures of $kT_1 \sim 0.2$ keV and $kT_2 \sim 0.5-0.9$ keV, with the hotter component being much more pronounced near 30 Dor and the X-ray spur. In 30 Dor, the plasma has most likely been heated by massive stellar winds and supernova remnants. In the X-ray spur, we find no evidence of heating by stars. Instead, the X-ray spur must have been compressed and heated by the collision of the HI gas., Comment: 21 pages, 20 figures, published in Astronomy & Astrophysics
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- 2021
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132. RX J0529.8-6556: a BeXRB pulsar with an evolving optical period and out of phase X-ray outbursts
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Treiber, H., Vasilopoulos, G., Bailyn, C. D., Haberl, F., Gendreau, K. C., Ray, P. S., Maitra, C., Maggi, P., Jaisawal, G. K., Udalski, A., Wilms, J., Monageng, I. M., Buckley, D. A. H., König, O., and Carpano, S.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We report the results of eROSITA and NICER observations of the June 2020 outburst of the Be/X-ray binary pulsar RX J0529.8-6556 in the Large Magellanic Cloud, along with the analysis of archival X-ray and optical data from this source. We find two anomalous features in the system's behavior. First, the pulse profile observed by NICER during maximum luminosity is similar to that observed by XMM-Newton in 2000, despite the fact that the X-ray luminosity was different by two orders of magnitude. By contrast, a modest decrease in luminosity in the 2020 observations generated a significant change in pulse profile. Second, we find that the historical optical outbursts are not strictly periodic, as would be expected if the outbursts were triggered by periastron passage, as is generally assumed. The optical peaks are also not coincident with the X-ray outbursts. We suggest that this behavior may result from a misalignment of the Be star disk and the orbital plane, which might cause changes in the timing of the passage of the neutron star through the disk as it precesses. We conclude that the orbital period of the source remains unclear., Comment: 15 pages, 14 figures, accepted by MNRAS
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- 2021
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133. XMMU J050722.1-684758: Discovery of a new Be X-ray binary pulsar likely associated with the supernova remnant MCSNR J0507-6847
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Maitra, C., Haberl, F., Maggi, P., Kavanagh, P., Vasilopoulos, G., Sasaki, M., Filipovic, M. D., and Udalski, A.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We report the discovery of a new high mass X-ray binary pulsar, XMMU J050722.1-684758, possibly associated with the supernova remnant MCSNR J0507-6847 in the Large Magellanic Cloud, using XMM-Newton X-ray observations. Pulsations with a periodicity of 570 s are discovered from the Be X-ray binary XMMU J050722.1-684758 confirming its nature as a HMXB pulsar. The HMXB is located near the geometric centre of the supernova remnant MCSNR J0507-6847 (0.9 arcmin from the centre) which supports the XRB-SNR association. The estimated age of the supernova remnant is 43-63 kyr which points to a middle aged to old supernova remnant. The large diameter of the supernova remnant combined with the lack of distinctive shell counterparts in optical and radio indicates that the SNR is expanding into the tenous environment of the superbubble N103. The estimated magnetic field strength of the neutron star is $B\gtrsim10^{14}$ G assuming a spin equilibrium condition which is expected from the estimated age of the parent remnant and assuming that the measured mass-accretion rate remained constant throughout., Comment: 12 pages, 13 figures, accepted for publication in MNRAS
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- 2021
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134. Chandra probes the X-ray variability of M51 ULX-7: evidence of propeller transition and X-ray dips on orbital periods
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Vasilopoulos, G., Koliopanos, F., Haberl, F., Treiber, H., Brightman, M., Earnshaw, H. P., and Gúrpide, A.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We report on the temporal properties of the ULX pulsar M51 ULX-7 inferred from the analysis of the 2018-2020 Swift/XRT monitoring data and archival Chandra data obtained over a period of 33 days in 2012. We find an extended low flux state, which might be indicative of propeller transition, lending further support to the interpretation that the NS is rotating near equilibrium. Alternatively, this off state could be related to a variable super-orbital period. Moreover, we report the discovery of periodic dips in the X-ray light curve that are associated with the binary orbital period. The presence of the dips implies a configuration where the orbital plane of the binary is closer to an edge on orientation, and thus demonstrates that favorable geometries are not necessary in order to observe ULX pulsars.These characteristics are similar to those seen in prototypical X-ray pulsars like Her X-1 and SMC X-1 or other ULX pulsars like NGC 5907 ULX1., Comment: 11 pages, 5 figures, Accepted to APJ
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- 2021
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135. Fast flaring observed from XMMU J053108.3-690923 by eROSITA: a supergiant fast X-ray transient in the Large Magellanic Cloud
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Maitra, C., Haberl, F., Vasilopoulos, G., Ducci, L., Dennerl, K., and Carpano, S.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Supergiant fast X-ray transients (SFXTs) are a peculiar class of supergiant high-mass X-ray binary (HMXB) systems characterised by extreme variability in the X-ray domain. In current models, this is mainly attributed to the clumpy nature of the stellar wind coupled with gating mechanisms involving the spin and magnetic field of the neutron star. We studied the X-ray properties of the supergiant HMXB XMMU J053108.3-690923 in the Large Magellanic Cloud to understand its nature. We performed a detailed temporal and spectral analysis of the eROSITA and XMM-Newton data of XMMU J053108.3-690923. We confirm the putative pulsations previously reported for the source with high confidence, certifying its nature as a neutron star in orbit with a supergiant companion. We identify the extremely variable nature of the source in the form of flares seen in the eROSITA light curves. The source flux exhibits a total dynamic range of more than three orders of magnitude, which confirms its nature as an SFXT, and is the first such direct evidence from a HMXB outside our Galaxy exhibiting a very high dynamic range in luminosity as well as a fast flaring behaviour. We detect changes in the hardness ratio during the flaring intervals where the hardness ratio reaches its minimum during the peak of the flare and increases steeply shortly afterwards. This is also supported by the results of the spectral analysis carried out at the peak and off-flare intervals. This scenario is consistent with the presence of dense structures in the supergiant wind of XMMU J053108.3-690923 where the clumpy medium becomes photoionised at the peak of the flare leading to a drop in the photo-electric absorption. Further, we provide an estimate of the clumpiness of the medium and the magnetic field of the neutron star assuming a spin equilibrium condition., Comment: 11 pages, 10 figures, Accepted for publication in A&A on 05/11/2020
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- 2020
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136. Detection of large-scale X-ray bubbles in the Milky Way halo
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Predehl, P., Sunyaev, R. A., Becker, W., Brunner, H., Burenin, R., Bykov, A., Cherepashchuk, A., Chugai, N., Churazov, E., Doroshenko, V., Eismont, N., Freyberg, M., Gilfanov, M., Haberl, F., Khabibullin, I., Krivonos, R., Maitra, C., Medvedev, P., Merloni, A., Nandra, K., Nazarov, V., Pavlinsky, M., Ponti, G., Sanders, J. S., Sasaki, M., Sazonov, S., Strong, A. W., and Wilms, J.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
The halo of the Milky Way provides a laboratory to study the properties of the shocked hot gas that is predicted by models of galaxy formation. There is observational evidence of energy injection into the halo from past activity in the nucleus of the Milky Way; however, the origin of this energy (star formation or supermassive-black-hole activity) is uncertain, and the causal connection between nuclear structures and large-scale features has not been established unequivocally. Here we report soft-X-ray-emitting bubbles that extend approximately 14 kiloparsecs above and below the Galactic centre and include a structure in the southern sky analogous to the North Polar Spur. The sharp boundaries of these bubbles trace collisionless and non-radiative shocks, and corroborate the idea that the bubbles are not a remnant of a local supernova but part of a vast Galaxy-scale structure closely related to features seen in gamma-rays. Large energy injections from the Galactic centre are the most likely cause of both the {\gamma}-ray and X-ray bubbles. The latter have an estimated energy of around 10$^{56}$ erg, which is sufficient to perturb the structure, energy content and chemical enrichment of the circumgalactic medium of the Milky Way., Comment: Author's version. 17 pages, 5 figures, Published in Nature 2020, Vol 588
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- 2020
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137. Lane Change Model for Automated Vehicles on Multi-Lane Highways in Mixed Traffic.
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Felix Hofinger, Marlies Mischinger-Rodziewicz, Michael Haberl, and Martin Fellendorf
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- 2023
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138. IEEE BigData 2023 Keystroke Verification Challenge (KVC).
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Giuseppe Stragapede, Rubén Vera-Rodríguez, Ruben Tolosana, Aythami Morales, Ivan DeAndres-Tame, Naser Damer, Julian Fiérrez, Javier Ortega-Garcia, Nahuel González, Andrei Shadrikov, Dmitrii Gordin, Leon Schmitt, Daniel Wimmer, Christoph Großmann, Joerdis Krieger, Florian Heinz, Ron Krestel, Christoffer Mayer, Simon Haberl, Helena Gschrey, Yosuke Yamagishi, Sanjay Saha, Sanka Rasnayaka, Sandareka Wickramanayake, Terence Sim, Weronika Gutfeter, Adam Baran, Mateusz Krzyszton, and Przemyslaw Jaskola
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- 2023
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139. Bias, Variance, and Threshold Level of the Least Squares Pitch Estimator with Windowed Data.
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Jonas Lindenberger, Stefan Schuster, Oliver Lang, Alexander Haberl, Clemens Staudinger, Theresa Roland, and Mario Huemer
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- 2023
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140. Societal Boundaries
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Brand, Ulrich, Muraca, Barbara, Pineault, Éric, Sahakian, Marlyne, Schaffartzik, Anke, Novy, Andreas, Streissler, Christoph, Haberl, Helmut, Asara, Viviana, Dietz, Kristina, Lang, Miriam, Kothari, Ashish, Smith, Tone, Spash, Clive, Brad, Alina, Pichler, Melanie, Plank, Christina, Velegrakis, Giorgos, Jahn, Thomas, Carter, Angela, Huan, Qingzhi, Kallis, Giorgos, Alier, Joan Martínez, Riva, Gabriel, Satgar, Vishwas, Mantovani, Emiliano Teran, Williams, Michelle, Wissen, Markus, Görg, Christoph, Wallenhorst, Nathanaël, editor, and Wulf, Christoph, editor
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- 2023
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141. Planetary Boundaries
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Brand, Ulrich, Muraca, Barbara, Pineault, Éric, Sahakian, Marlyne, Schaffartzik, Anke, Novy, Andreas, Streissler, Christoph, Haberl, Helmut, Asara, Viviana, Dietz, Kristina, Lang, Miriam, Kothari, Ashish, Smith, Tone, Spash, Clive, Brad, Alina, Pichler, Melanie, Plank, Christina, Velegrakis, Giorgos, Jahn, Thomas, Carter, Angela, Huan, Qingzhi, Kallis, Giorgos, Alier, Joan Martínez, Riva, Gabriel, Satgar, Vishwas, Mantovani, Emiliano Teran, Williams, Michelle, Wissen, Markus, Görg, Christoph, Wallenhorst, Nathanaël, editor, and Wulf, Christoph, editor
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- 2023
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142. Socio-metabolic Transitions
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Haberl, Helmut, Fischer-Kowalski, Marina, Krausmann, Fridolin, Schmid, Martin, Hensel, Michael U., Series Editor, Binder, Claudia R., Series Editor, Hensel, Defne Sunguroglu, Series Editor, Ludwig, Ferdinand, Series Editor, and Sunguroğlu Hensel, Defne, editor
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- 2023
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143. Search for High-Pressure Silicon Phases: Reaching the Extreme Conditions with High-Intensity Laser Irradiation
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Rapp, Ludovic, Matsuoka, Takeshi, Firestein, Konstantin L., Sagae, Daisuke, Habara, Hideaki, Mukai, Keiichiro, Tanaka, Kazuo A., Gamaly, Eugene, Kodama, Ryosuke, Seto, Yusuke, Shobu, Takahisa, Tominaga, Aki, Smillie, Lachlan, Haberl, Bianca, Pikuz, Tatiana, Yabuuchi, Toshinori, Togashi, Tadashi, Inubushi, Yuichi, Yabashi, Makina, Juodkazis, Saulius, Golberg, Dmitri V., Rode, Andrei V., Ozaki, Norimasa, Lotsch, H.K.V., Founding Editor, Rhodes, William T., Editor-in-Chief, Adibi, Ali, Series Editor, Asakura, Toshimitsu, Series Editor, Hänsch, Theodor W., Series Editor, Krausz, Ferenc, Series Editor, Masters, Barry R., Series Editor, Midorikawa, Katsumi, Series Editor, Venghaus, Herbert, Series Editor, Weber, Horst, Series Editor, Weinfurter, Harald, Series Editor, Kobayashi, Kazuya, Series Editor, Markel, Vadim, Series Editor, Stoian, Razvan, editor, and Bonse, Jörn, editor
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- 2023
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144. Options for reducing a city's global biodiversity footprint – The case of food consumption in Vienna
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Matej, Sarah, Kaufmann, Lisa, Semenchuk, Philipp, Dullinger, Stefan, Essl, Franz, Haberl, Helmut, Kalt, Gerald, Kastner, Thomas, Lauk, Christian, Krausmann, Fridolin, and Erb, Karl-Heinz
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- 2024
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145. Localized APP expression results in progressive network dysfunction by disorganizing spike timing
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Viana da Silva, Silvia, Haberl, Matthias G., Gaur, Kshitij, Patel, Rina, Narayan, Gautam, Ledakis, Max, Fu, Maylin L., de Castro Vieira, Miguel, Koo, Edward H., Leutgeb, Jill K., and Leutgeb, Stefan
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- 2024
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146. Mapping and modelling global mobility infrastructure stocks, material flows and their embodied greenhouse gas emissions
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Wiedenhofer, Dominik, Baumgart, André, Matej, Sarah, Virág, Doris, Kalt, Gerald, Lanau, Maud, Tingley, Danielle Densley, Liu, Zhiwei, Guo, Jing, Tanikawa, Hiroki, and Haberl, Helmut
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- 2024
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147. Built structures influence patterns of energy demand and CO2 emissions across countries
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Helmut Haberl, Markus Löw, Alejandro Perez-Laborda, Sarah Matej, Barbara Plank, Dominik Wiedenhofer, Felix Creutzig, Karl-Heinz Erb, and Juan Antonio Duro
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Science - Abstract
Abstract Built structures, i.e. the patterns of settlements and transport infrastructures, are known to influence per-capita energy demand and CO2 emissions at the urban level. At the national level, the role of built structures is seldom considered due to poor data availability. Instead, other potential determinants of energy demand and CO2 emissions, primarily GDP, are more frequently assessed. We present a set of national-level indicators to characterize patterns of built structures. We quantify these indicators for 113 countries and statistically analyze the results along with final energy use and territorial CO2 emissions, as well as factors commonly included in national-level analyses of determinants of energy use and emissions. We find that these indicators are about equally important for predicting energy demand and CO2 emissions as GDP and other conventional factors. The area of built-up land per capita is the most important predictor, second only to the effect of GDP.
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- 2023
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148. Assessing SOFA score trajectories in sepsis using machine learning: A pragmatic approach to improve the accuracy of mortality prediction.
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Lars Palmowski, Hartmuth Nowak, Andrea Witowski, Björn Koos, Alexander Wolf, Maike Weber, Daniel Kleefisch, Matthias Unterberg, Helge Haberl, Alexander von Busch, Christian Ertmer, Alexander Zarbock, Christian Bode, Christian Putensen, Ulrich Limper, Frank Wappler, Thomas Köhler, Dietrich Henzler, Daniel Oswald, Björn Ellger, Stefan F Ehrentraut, Lars Bergmann, Katharina Rump, Dominik Ziehe, Nina Babel, Barbara Sitek, Katrin Marcus, Ulrich H Frey, Patrick J Thoral, Michael Adamzik, Martin Eisenacher, Tim Rahmel, and SepsisDataNet.NRW research group
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Medicine ,Science - Abstract
IntroductionAn increasing amount of longitudinal health data is available on critically ill septic patients in the age of digital medicine, including daily sequential organ failure assessment (SOFA) score measurements. Thus, the assessment in sepsis focuses increasingly on the evaluation of the individual disease's trajectory. Machine learning (ML) algorithms may provide a promising approach here to improve the evaluation of daily SOFA score dynamics. We tested whether ML algorithms can outperform the conventional ΔSOFA score regarding the accuracy of 30-day mortality prediction.MethodsWe used the multicentric SepsisDataNet.NRW study cohort that prospectively enrolled 252 sepsis patients between 03/2018 and 09/2019 for training ML algorithms, i.e. support vector machine (SVM) with polynomial kernel and artificial neural network (aNN). We used the Amsterdam UMC database covering 1,790 sepsis patients for external and independent validation.ResultsBoth SVM (AUC 0.84; 95% CI: 0.71-0.96) and aNN (AUC 0.82; 95% CI: 0.69-0.95) assessing the SOFA scores of the first seven days led to a more accurate prognosis of 30-day mortality compared to the ΔSOFA score between day 1 and 7 (AUC 0.73; 95% CI: 0.65-0.80; p = 0.02 and p = 0.05, respectively). These differences were even more prominent the shorter the time interval considered. Using the SOFA scores of day 1 to 3 SVM (AUC 0.82; 95% CI: 0.68 0.95) and aNN (AUC 0.80; 95% CI: 0.660.93) led to a more accurate prognosis of 30-day mortality compared to the ΔSOFA score (AUC 0.66; 95% CI: 0.58-0.74; p < 0.01 and p < 0.01, respectively). Strikingly, all these findings could be confirmed in the independent external validation cohort.ConclusionsThe ML-based algorithms using daily SOFA scores markedly improved the accuracy of mortality compared to the conventional ΔSOFA score. Therefore, this approach could provide a promising and automated approach to assess the individual disease trajectory in sepsis. These findings reflect the potential of incorporating ML algorithms as robust and generalizable support tools on intensive care units.
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- 2024
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149. Inactivation of antibiotic-resistant bacteria Escherichia coli by electroporation
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Saša Haberl Meglič, Dejan Slokar, and Damijan Miklavčič
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electroporation ,antibiotic resistant bacteria ,inactivation ,tetracycline ,chloramphenicol ,Escherichia coli ,Microbiology ,QR1-502 - Abstract
IntroductionIn modern times, bacterial infections have become a growing problem in the medical community due to the emergence of antibiotic-resistant bacteria. In fact, the overuse and improper disposal of antibiotics have led to bacterial resistance and the presence of such bacteria in wastewater. Therefore, it is critical to develop effective strategies for dealing with antibiotic-resistant bacteria in wastewater. Electroporation has been found to be one of the most promising complementary techniques for bacterial inactivation because it is effective against a wide range of bacteria, is non-chemical and is highly optimizable. Many studies have demonstrated electroporation-assisted inactivation of bacteria, but rarely have clinical antibiotics or bacteria resistant to these antibiotics been used in the study. Therefore, the motivation for our study was to use a treatment regimen that combines antibiotics and electroporation to inactivate antibiotic-resistant bacteria.MethodsWe separately combined two antibiotics (tetracycline and chloramphenicol) to which the bacteria are resistant (with a different resistance mode) and electric pulses. We used three different concentrations of antibiotics (40, 80 and 150 µg/ml for tetracycline and 100, 500 and 2000 µg/ml for chloramphenicol, respectively) and four different electric field strengths (5, 10, 15 and 20 kV/cm) for electroporation.Results and discussionOur results show that electroporation effectively enhances the effect of antibiotics and inactivates antibiotic-resistant bacteria. The inactivation rate for tetracycline or chloramphenicol was found to be different and to increase with the strength of the pulsed electric field and/or the concentration of the antibiotic. In addition, we show that electroporation has a longer lasting effect (up to 24 hours), making bacteria vulnerable for a considerable time. The present work provides new insights into the use of electroporation to inactivate antibiotic-resistant bacteria in the aquatic environment.
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- 2024
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150. Clinical outcome of rural in-hospital-stroke patients after interhospital transfer for endovascular therapy within a telemedical stroke network in Germany: a registry-based observational study
- Author
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Gordian Jan Hubert, Nikolai Dominik Hubert, Christoph Trumm, Miriam Antonia Leitner, Laura Paternoster, Moritz Immanuel Leitner, Jan Martin Rémi, and Roman Ludwig Haberl
- Subjects
Medicine - Abstract
Objectives Little is known about in-hospital-stroke (IHS) patients with large vessel occlusion and subsequent transfer to referral centres for endovascular therapy (EVT). However, this subgroup is highly relevant given the substantial amount of IHS, the ongoing trend towards greater use of EVT and lack of EVT possibilities in rural hospitals. The study objective is to explore the clinical outcomes of this vulnerable patient group, given that both IHS and interhospital transfer are associated with worse clinical outcomes due to a higher proportion of pre-existing conditions and substantial time delays during transfer.Design and setting Prospectively collected data of patients receiving EVT after interhospital transfer from 14 rural hospitals of the Telemedical Stroke Network in Southeast Bavaria (TEMPiS) between February 2018 and July 2020 was analysed.Participants 49 IHS and 274 out-of-hospital-stroke (OHS) patients were included.Outcome measures Baseline characteristics, treatment times and outcomes were compared between IHS and OHS. The primary endpoint was a 3-month modified Rankin Scale (mRS).Results In IHS patients, atrial fibrillation (55.3% vs 35.9%, p=0.012), diabetes (36.2% vs 21.1%, p=0.024) and use of oral anticoagulants (44.7% vs 20.8%, p
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- 2024
- Full Text
- View/download PDF
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