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7,313 results on '"GIUNTI A."'

102. Blood and cerebellar abundance of ATXN3 splice variants in spinocerebellar ataxia type 3/Machado-Joseph disease

Author

Raposo, Mafalda, Hübener-Schmid, Jeannette, Tagett, Rebecca, Ferreira, Ana F., Vieira Melo, Ana Rosa, Vasconcelos, João, Pires, Paula, Kay, Teresa, Garcia-Moreno, Hector, Giunti, Paola, Santana, Magda M., Pereira de Almeida, Luis, Infante, Jon, van de Warrenburg, Bart P., de Vries, Jeroen J., Faber, Jennifer, Klockgether, Thomas, Casadei, Nicolas, Admard, Jakob, Schöls, Ludger, Riess, Olaf, Costa, Maria do Carmo, and Lima, Manuela

Published
2024
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103. Evidence of 100 TeV $\gamma$-ray emission from HESS J1702-420: A new PeVatron candidate

Author

Abdalla, H., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Martins, V. Barbosa, Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Breuhaus, M., Brun, F., Brun, P., Bryan, M., Büchele, M., Bulik, T., Bylund, T., Caroff, S., Carosi, A., Casanova, S., Chand, T., Chandra, S., Chen, A., Cotter, G., Curyło, M., Mbarubucyeye, J. Damascene, Davids, I. D., Davies, J., Deil, C., Devin, J., Dirson, L., Djannati-Atai, A., Dmytriiev, A., Donath, A., Doroshenko, V., Dreyer, L., Duffy, C., Dyks, J., Egberts, K., Eichhorn, F., Einecke, S., Emery, G., Ernenwein, J. -P., Feijen, K., Fegan, S., Fiasson, A., de Clairfontaine, G. Fichet, Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Grondin, M. -H., Hahn, J., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huber, D., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kasai, E., Kastendieck, M. A., Katarzynski, K., Katz, U., Khangulyan, D., Khélifi, B., Klepser, S., Kluźniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leuschner, F., Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martí-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Meyer, M., Mitchell, A., Moderski, R., Mohrmann, L., Montanari, A., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, K., Nayerhoda, A., de Naurois, M., Ndiyavala, H., Niemiec, J., Oakes, L., O'Brien, P., Odaka, H., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Panny, S., Panter, M., Parsons, R. D., Peron, G., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. Priyana, Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Raab, S., Rauth, R., Reichherzer, P., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Sailer, S., Salzmann, H., Sanchez, D. A., Santangelo, A., Sasaki, M., Scalici, M., Schäfer, J., Schüssler, F., Schutte, H. M., Schwanke, U., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shapopi, J. N. S., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, L., Sun, L., Steenkamp, R., Stegmann, C., Steinmassl, S., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Thiersen, J. H. E., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Vincent, P., Vink, J., Völk, H. J., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Wong, Yu Wun, Yusafzai, A., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S. J., Zorn, J., Zouari, S., Żywucka, N., and Acero, F.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

The identification of PeVatrons, hadronic particle accelerators reaching the knee of the cosmic ray spectrum (few $10^{15}$ eV), is crucial to understand the origin of cosmic rays in the Galaxy. We provide an update on the unidentified source HESS J1702-420, a promising PeVatron candidate. We present new observations of HESS J1702-420 made with the High Energy Stereoscopic System (H.E.S.S.), and processed using improved analysis techniques. The analysis configuration was optimized to enhance the collection area at the highest energies. We applied a three-dimensional (3D) likelihood analysis to model the source region and adjust non thermal radiative spectral models to the $\gamma$-ray data. We also analyzed archival data from the Fermi Large Area Telescope (LAT) to constrain the source spectrum at $\gamma$-ray energies >10 GeV. We report the detection of a new source component called HESS J1702-420A, that was separated from the bulk of TeV emission at a $5.4\sigma$ confidence level. The power law $\gamma$-ray spectrum of HESS J1702-420A extends with an index of $\Gamma=1.53\pm0.19_\text{stat}\pm0.20_\text{sys}$ and without curvature up to the energy band 64-113 TeV, in which it was detected by H.E.S.S. at a $4.0\sigma$ confidence level. This brings evidence for the source emission up to $100\,\text{TeV}$, which makes HESS J1702-420A a compelling candidate site for the presence of extremely high energy cosmic rays. Remarkably, in a hadronic scenario, the cut-off energy of the proton distribution powering HESS J1702-420A is found to be higher than 0.5 PeV at a 95% confidence level. HESS J1702-420A becomes therefore one of the most solid PeVatron candidates detected so far in H.E.S.S. data, altough a leptonic origin of its emission could not be ruled out either., Comment: Accepted for publication in the 2. Astrophysical processes section of Astronomy & Astrophysics

Published
2021
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104. Search for dark matter annihilation signals from unidentified Fermi-LAT objects with H.E.S.S

Author

Collaboration, H. E. S. S., Abdallah, H., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Martins, V. Barbosa, Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Breuhaus, M., Brose, R., Brun, F., Bulik, T., Bylund, T., Cangemi, F., Caroff, S., Casanova, S., Chambery, P., Chand, J. Catalano T., Chen, A., Cotter, G., Curylo, M., Dalgleish, H., Mbarubucyeye, J. Damascene, Davids, I. D., Davies, J., Devin, J., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Dreyer, L., Plessis, L. Du, Duffy, C., Egberts, K., Einecke, S., Emery, G., Ernenwein, J. -P., Feijen, K., Fegan, S., Fiasson, A., de Clairfontaine, G. Fichet, Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Grondin, M. -H., Hattingh, S., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huang, Z., Huber, D., Jamrozy, M., Jankowsky, D., Jankowsky, F., Joshi, V., Jung-Richardt, I., Kasai, E., Katarzyński, K., Katz, U., Khangulyan, D., Khèlifi, B., Klepser, S., Kluzniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Mezek, G. Kukec, Kundu, A., Lamanna, G., Stum, S. Le, Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leuschner, F., Levy, C., Lohse, T., Luashvili, A., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martì-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Meyer, M., Mitchell, A., Moderski, R., Mohrmann, L., Montanari, A., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, K., Nayerhoda, A., de Naurois, M., Ndiyavala, H., Niemiec, J., Noel, A., Oberholzer, L., O'Brien, P., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Panter, M., Panny, S., Parsons, R. D., Peron, G., Pita, S., Poireau, V., Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Reichherzer, P., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Romoli, C., Rowell, G., Rudak, B., Ricarte, H. Rueda, Ruiz-Velasco, E., Sahakian, V., Sailer, S., Salzmann, H., Sanchez, D. A., Santangelo, A., Sasaki, M., Schüssler, F., Schutte, H. M., Schwanke, U., Senniappan, M., Seyffert, A. S., Shapopi, J. N. S., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Spackman, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, L., Sun, L., Steenkamp, R., Stegmann, C., Steinmassl, S., Steppa, C., Takahashi, T., Tanaka, T., Tavernier, T., Taylor, A. M., Terrier, R., Morgan, C. Thorpe, Thiersen, J. H. E., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tsuji, M., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Viana, A., Vincent, P., Vink, J., Völk, H. J., Wagner, S. J., Werner, F., White, R., Wierzcholska, A., Wong, Yu Wun, Yassin, H., Yusafzai, A., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S., Zmija, A., Zorn, J., Zouari, S., and Zywucka, N.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

Cosmological $N$-body simulations show that Milky Way-sized galaxies harbor a population of unmerged dark matter subhalos. These subhalos could shine in gamma-rays and be eventually detected in gamma-ray surveys as unidentified sources. We performed a thorough selection among unidentified Fermi-LAT Objects (UFOs) to identify them as possible TeV-scale dark matter subhalo candidates. We search for very-high-energy (E $\gtrsim$ 100 GeV) gamma-ray emissions using H.E.S.S. observations towards four selected UFOs. Since no significant very-high-energy gamma-ray emission is detected in any dataset of the four observed UFOs nor in the combined UFO dataset, strong constraints are derived on the product of the velocity-weighted annihilation cross section $\langle \sigma v \rangle$ by the $J$-factor for the dark matter models. The 95% C.L. observed upper limits derived from combined H.E.S.S. observations reach $\langle \sigma v \rangle J$ values of 3.7$\times$10$^{-5}$ and 8.1$\times$10$^{-6}$ GeV$^2$cm$^{-2}$s$^{-1}$ in the $W^+W^-$ and $\tau^+\tau^-$ channels, respectively, for a 1 TeV dark matter mass. Focusing on thermal WIMPs, the H.E.S.S. constraints restrict the $J$-factors to lie in the range 6.1$\times$10$^{19}$ - 2.0$\times$10$^{21}$ GeV$^2$cm$^{-5}$, and the masses to lie between 0.2 and 6 TeV in the $W^+W^-$ channel. For the $\tau^+\tau^-$ channel, the $J$-factors lie in the range 7.0$\times$10$^{19}$ - 7.1$\times$10$^{20}$ GeV$^2$cm$^{-5}$ and the masses lie between 0.2 and 0.5 TeV. Assuming model-dependent predictions from cosmological N-body simulations on the $J$-factor distribution for Milky Way-sized galaxies, the dark matter models with masses greater than 0.3 TeV for the UFO emissions can be ruled out at high confidence level., Comment: 11 pages, 7 figures, matches accepted version in The Astrophysical Journal

Published
2021
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105. Search for dark matter annihilation in the dwarf irregular galaxy WLM with H.E.S.S

Author

Collaboration, H. E. S. S., Abdallah, H., Adam, R., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Martins, V. Barbosa, Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Breuhaus, M., Brun, F., Brun, P., Bryan, M., Büchele, M., Bulik, T., Bylund, T., Caroff, S., Carosi, A., Casanova, S., Chand, T., Chandra, S., Chen, A., Cotter, G., Curylo, M., Mbarubucyeye, J. Damascene, Davids, I. D., Davies, J., Deil, C., Devin, J., deWilt, P., Dirson, L., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Duffy, C., Dyks, J., Egberts, K., Eichhorn, F., Einecke, S., Emery, G., Ernenwein, J. -P., Feijen, K., Fegan, S., Fiasson, A., de Clairfontaine, G. Fichet, Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Gottschall, D., Grondin, M. -H., Hahn, J., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huber, D., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kasai, E., Kastendieck, M. A., Katarzyński, K., Katz, U., Khangulyan, D., Khèlifi, B., Klepser, S., Kluzniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martì-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Meyer, M., Moderski, R., Mohamed, M., Mohrmann, L., Montanari, A., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, K., Nayerhoda, A., de Naurois, M., Ndiyavala, H., Niederwanger, F., Niemiec, J., Oakes, L., O'Brien, P., Odaka, H., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Panter, M., Panny, S., Parsons, R. D., Peron, G., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. Priyana, Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Raab, S., Rauth, R., Reichherzer, P., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Sailer, S., Sanchez, D. A., Santangelo, A., Sasaki, M., Scalici, M., Schüssler, F., Schutte, H. M., Schwanke, U., Schwemmer, S., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, L., Sun, L., Steenkamp, R., Stegmann, C., Steinmassl, S., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Vincent, P., Vink, J., Völk, H. J., Vuillaume, T., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Wong, Yu Wun, Yusafzai, A., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S., Zorn, J., Zouari, S., and Zywucka, N.

Subjects
Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Experiment
Abstract

We search for an indirect signal of dark matter through very high-energy gamma rays from the Wolf-Lundmark-Melotte (WLM) dwarf irregular galaxy. The pair annihilation of dark matter particles would produce Standard Model particles in the final state such as gamma rays, which might be detected by ground-based Cherenkov telescopes. Dwarf irregular galaxies represent promising targets as they are dark matter dominated objects with well measured kinematics and small uncertainties on their dark matter distribution profiles. In 2018, the H.E.S.S. five-telescope array observed the dwarf irregular galaxy WLM for 18 hours. We present the first analysis based on data obtained from an imaging atmospheric Cherenkov telescope for this subclass of dwarf galaxy. As we do not observe any significant excess in the direction of WLM, we interpret the result in terms of constraints on the velocity-weighted cross section for dark matter pair annihilation as a function of the dark matter particle mass for various continuum channels as well as the prompt gamma-gamma emission. For the $\tau^+\tau^-$ channel the limits reach a $\langle \sigma v \rangle$ value of about $4\times 10^{-22}$ cm3s-1 for a dark matter particle mass of 1 TeV. For the prompt gamma-gamma channel, the upper limit reaches a $\langle \sigma v \rangle$ value of about $5 \times10^{-24}$ cm3s-1 for a mass of 370 GeV. These limits represent an improvement of up to a factor 200 with respect to previous results for the dwarf irregular galaxies for TeV dark matter search., Comment: 13 pages, 5 figures

Published
2021
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106. Muon and electron g-2 and proton and cesium weak charges implications on dark $\mathbf{Z_d}$ models

Author

Cadeddu, M., Cargioli, N., Dordei, F., Giunti, C., and Picciau, E.

Subjects
High Energy Physics - Phenomenology
Abstract

Theories beyond the standard model involving a sub-GeV-scale vector $Z_d$ mediator have been largely studied as a possible explanation of the experimental values of the muon and electron anomalous magnetic moments. Motivated by the recent determination of the anomalous muon magnetic moment performed at Fermilab, we derive the constraints on such a model obtained from the magnetic moment determinations and the measurements of the proton and cesium weak charge, $Q_W$, performed at low-energy transfer. In order to do so, we revisit the determination of the cesium $Q_W$ from the atomic parity violation experiment, which depends critically on the value of the average neutron rms radius of $^{133}\text{Cs}$, by determining the latter from a practically model-independent extrapolation from the recent average neutron rms radius of $^{208}\text{Pb}$ performed by the PREX-2 Collaboration. From a combined fit of all the aforementioned experimental results, we obtain rather precise limits on the mass and the kinetic mixing parameter of the $Z_d$ boson, namely $m_{Z_d} = 47{}^{+61}_{-16} \, \mathrm{MeV}$ and $\varepsilon = 2.3{}^{+1.1}_{-0.4} \times 10^{-3}$, when marginalizing over the $Z-Z_d$ mass mixing parameter $\delta$., Comment: 6 pages, 5 figures. Matches version published in Physical Review D Letter

Published
2021
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108. Non-unitary neutrino mixing in short and long-baseline experiments

Author

Forero, D. V., Giunti, C., Ternes, C. A., and Tortola, M.

Subjects
High Energy Physics - Phenomenology
Abstract

Non-unitary neutrino mixing in the light neutrino sector is a direct consequence of type-I seesaw neutrino mass models. In these models, light neutrino mixing is described by a sub-matrix of the full lepton mixing matrix and, then, it is not unitary in general. In consequence, neutrino oscillations are characterized by additional parameters, including new sources of CP violation. Here we perform a combined analysis of short and long-baseline neutrino oscillation data in this extended mixing scenario. We did not find a significant deviation from unitary mixing, and the complementary data sets have been used to constrain the non-unitarity parameters. We have also found that the T2K and NOvA tension in the determination of the Dirac CP-phase is not alleviated in the context of non-unitary neutrino mixing., Comment: 18 pages

Published
2021
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109. New insights into nuclear physics and weak mixing angle using electroweak probes

Author

Cadeddu, M., Cargioli, N., Dordei, F., Giunti, C., Li, Y. F., Picciau, E., Ternes, C. A., and Zhang, Y. Y.

Subjects
High Energy Physics - Phenomenology, Nuclear Theory
Abstract

Using the new results on coherent elastic neutrino-nucleus scattering data in cesium-iodide provided by the COHERENT experiment, we determine a new measurement of the average neutron rms radius of $^{133}\text{Cs}$ and $^{127}\text{I}$. In combination with the atomic parity violation (APV) experimental result, we derive the most precise measurement of the neutron rms radii of $^{133}\text{Cs}$ and $^{127}\text{I}$, disentangling for the first time the contributions of the two nuclei. By exploiting these measurements we determine the corresponding neutron skin values for $^{133}\text{Cs}$ and $^{127}\text{I}$. These results suggest a preference for models which predict large neutron skin values, as corroborated by the only other electroweak measurements of the neutron skin of $^{208}\text{Pb}$ performed by PREX experiments. Moreover, for the first time, we obtain a data-driven APV+COHERENT measurement of the low-energy weak mixing angle with a percent uncertainty, independent of the value of the average neutron rms radius of $^{133}\text{Cs}$ and $^{127}\text{I}$, that is allowed to vary freely in the fit. The value of the low-energy weak mixing angle that we found is slightly larger than the standard model prediction., Comment: 11 pages

Published
2021
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110. Neutrino-4 anomaly: oscillations or fluctuations?

Author

Giunti, C., Li, Y. F., Ternes, C. A., and Zhang, Y. Y.

Subjects
High Energy Physics - Phenomenology, High Energy Physics - Experiment
Abstract

We present a deep study of the Neutrino-4 data aimed at finding the statistical significance of the large-mixing short-baseline neutrino oscillation signal claimed by the Neutrino-4 collaboration at more than $3\sigma$. We found that the results of the Neutrino-4 collaboration can be reproduced approximately only by neglecting the effects of the energy resolution of the detector. Including these effects, we found that the best fit is obtained for a mixing that is even larger, close to maximal, but the statistical significance of the short-baseline neutrino oscillation signal is only about $2.7\sigma$ if evaluated with the usual method based on Wilks' theorem. We show that the large Neutrino-4 mixing is in strong tension with the KATRIN, PROSPECT, STEREO, and solar $\nu_{e}$ bounds. Using a more reliable Monte Carlo simulation of a large set of Neutrino-4-like data, we found that the statistical significance of the Neutrino-4 short-baseline neutrino oscillation signal decreases to about $2.2\sigma$. We also show that it is not unlikely to find a best-fit point that has a large mixing, even maximal, in the absence of oscillations. Therefore, we conclude that the claimed Neutrino-4 indication in favor of short-baseline neutrino oscillations with very large mixing is rather doubtful., Comment: 12 pages. Final version to be published in Physics Letters B

Published
2021
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111. Derivation of Darcy's law in randomly punctured domains

Author

Giunti, Arianna

Subjects
Mathematics - Analysis of PDEs, 35B27, 35J57, 35Q35, 60K35
Abstract

We consider the homogenization of a Poisson problem or a Stokes system in a randomly punctured domain with Dirichlet boundary conditions. We assume that the holes are spherical and have random centres and radii. We impose that the average distance between the balls is of size $\eps$ and their average radius is $\varepsilon^{\alpha}$, $\alpha \in (1; 3)$. We prove that, as in the periodic case [G. Allaire, ``Homogenization of the Navier-Stokes equations in domains perforated with tiny holes. II''], the solutions converge to the solution of Darcy's law (or its scalar analogue in the case of Poisson). In the same spirit of [A. Giunti, R. H\"ofer and J. Vel\'azquez, ``Homogenization of the Poisson equation in randomly perforated domains under minimal assumptions on the size of the holes''], we work under minimal conditions on the integrability of the random radii. These ensure that the problem is well-defined but do not rule out the onset of clusters of holes., Comment: 29 pp

Published
2021

112. Notes on pivot pairings

Author

Giunti, Barbara

Subjects
Computer Science - Computational Geometry, Mathematics - Algebraic Topology
Abstract

We present a row reduction algorithm to compute the barcode decomposition of persistence modules. This algorithm dualises the standard persistence one and clarifies the symmetry between clear and compress optimisations., Comment: 5 pages

Published
2021

115. Correction to: The frequency of non‑motor symptoms in SCA3 and their association with disease severity and lifestyle factors

Author

Hengel, Holger, Martus, Peter, Faber, Jennifer, Giunti, Paola, Garcia-Moreno, Hector, Solanky, Nita, Klockgether, Thomas, Reetz, Kathrin, van de Warrenburg, Bart P., Santana, Magda M., Silva, Patrick, Cunha, Inês, de Almeida, Luís Pereira, Timmann, Dagmar, Infante, Jon, de Vries, Jeroen, Lima, Manuela, Pires, Paula, Bushara, Khalaf, Jacobi, Heike, Onyike, Chiadi, Schmahmann, Jeremy D., Hübener-Schmid, Jeannette, Synofzik, Matthis, and Schöls, Ludger

Published
2024
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119. Neutrino oscillation bounds on quantum decoherence

Author

Valentina De Romeri, Carlo Giunti, Thomas Stuttard, and Christoph A. Ternes

Subjects
Non-Standard Neutrino Properties, Specific BSM Phenomenology, Neutrino Mixing, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We consider quantum-decoherence effects in neutrino oscillation data. Working in the open quantum system framework we adopt a phenomenological approach that allows to parameterize the energy dependence of the decoherence effects. We consider several phenomenological models. We analyze data from the reactor experiments RENO, Daya Bay and KamLAND and from the accelerator experiments NOvA, MINOS/MINOS+ and T2K. We obtain updated constraints on the decoherence parameters quantifying the strength of damping effects, which can be as low as Γ ij ≲ 8 × 10 −27 GeV at 90% confidence level in some cases. We also present sensitivities for the future facilities DUNE and JUNO.

Published
2023
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120. Nuclear neutron radius and weak mixing angle measurements from latest COHERENT CsI and atomic parity violation Cs data

Author

M. Atzori Corona, M. Cadeddu, N. Cargioli, F. Dordei, C. Giunti, and G. Masia

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The COHERENT collaboration observed coherent elastic neutrino nucleus scattering using a 14.6 kg cesium-iodide (CsI) detector in 2017 and recently published the updated results before decommissioning the detector. Here, we present the legacy determination of the weak mixing angle and of the average neutron rms radius of $$^{133}{\textrm{Cs}}$$ 133 Cs and $$^{127}{\textrm{I}}$$ 127 I obtained with the full CsI dataset, also exploiting the combination with the atomic parity violation (APV) experimental result, that allows us to achieve a precision as low as $$\sim $$ ∼ 4.5% and to disentangle the contributions of the $$^{133}{\textrm{Cs}}$$ 133 Cs and $$^{127}{\textrm{I}}$$ 127 I nuclei. Interestingly, we show that the COHERENT CsI data show a 6 $$\sigma $$ σ evidence of the nuclear structure suppression of the full coherence. Moreover, we derive a data-driven APV+COHERENT measurement of the low-energy weak mixing angle with a percent uncertainty, independent of the value of the average neutron rms radius of $$^{133}{\textrm{Cs}}$$ 133 Cs and $$^{127}{\textrm{I}},$$ 127 I , that is allowed to vary freely in the fit. Additionally, we extensively discuss the impact of using two different determinations of the theoretical parity non-conserving amplitude in the APV fit. Our findings show that the particular choice can make a significant difference, up to 6.5% on $$R_n$$ R n (Cs) and 11% on the weak mixing angle. Finally, in light of the recent announcement of a future deployment of a 10 kg and a $$\sim $$ ∼ 700 kg cryogenic CsI detectors, we provide future prospects for these measurements, comparing them with other competitive experiments that are foreseen in the near future.

Published
2023
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121. Effect of the ROCK inhibitor fasudil on the brain proteomic profile in the tau transgenic mouse model of Alzheimer's disease

Author

Roberto Collu, Zheng Yin, Elisa Giunti, Sarah Daley, Mei Chen, Peter Morin, Richard Killick, Stephen T. C. Wong, and Weiming Xia

Subjects
Alzheimer's disease, fasudil, PS19, P301S, tau, proteomic, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

IntroductionThe goal of this study is to explore the pharmacological potential of the amyloid-reducing vasodilator fasudil, a selective Ras homolog (Rho)-associated kinases (ROCK) inhibitor, in the P301S tau transgenic mouse model (Line PS19) of neurodegenerative tauopathy and Alzheimer's disease (AD).MethodsWe used LC-MS/MS, ELISA and bioinformatic approaches to investigate the effect of treatment with fasudil on the brain proteomic profile in PS19 tau transgenic mice. We also explored the efficacy of fasudil in reducing tau phosphorylation, and the potential beneficial and/or toxic effects of its administration in mice.ResultsProteomic profiling of mice brains exposed to fasudil revealed the activation of the mitochondrial tricarboxylic acid (TCA) cycle and blood-brain barrier (BBB) gap junction metabolic pathways. We also observed a significant negative correlation between the brain levels of phosphorylated tau (pTau) at residue 396 and both fasudil and its metabolite hydroxyfasudil.ConclusionsOur results provide evidence on the activation of proteins and pathways related to mitochondria and BBB functions by fasudil treatment and support its further development and therapeutic potential for AD.

Published
2024
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122. Cocreating an Automated mHealth Apps Systematic Review Process With Generative AI: Design Science Research Approach

Author

Guido Giunti and Colin P Doherty

Subjects
Special aspects of education, LC8-6691, Medicine (General), R5-920
Abstract

BackgroundThe use of mobile devices for delivering health-related services (mobile health [mHealth]) has rapidly increased, leading to a demand for summarizing the state of the art and practice through systematic reviews. However, the systematic review process is a resource-intensive and time-consuming process. Generative artificial intelligence (AI) has emerged as a potential solution to automate tedious tasks. ObjectiveThis study aimed to explore the feasibility of using generative AI tools to automate time-consuming and resource-intensive tasks in a systematic review process and assess the scope and limitations of using such tools. MethodsWe used the design science research methodology. The solution proposed is to use cocreation with a generative AI, such as ChatGPT, to produce software code that automates the process of conducting systematic reviews. ResultsA triggering prompt was generated, and assistance from the generative AI was used to guide the steps toward developing, executing, and debugging a Python script. Errors in code were solved through conversational exchange with ChatGPT, and a tentative script was created. The code pulled the mHealth solutions from the Google Play Store and searched their descriptions for keywords that hinted toward evidence base. The results were exported to a CSV file, which was compared to the initial outputs of other similar systematic review processes. ConclusionsThis study demonstrates the potential of using generative AI to automate the time-consuming process of conducting systematic reviews of mHealth apps. This approach could be particularly useful for researchers with limited coding skills. However, the study has limitations related to the design science research methodology, subjectivity bias, and the quality of the search results used to train the language model.

Published
2024
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123. Timing, Indicators, and Approaches to Digital Patient Experience Evaluation: Umbrella Systematic Review

Author

Tingting Wang, Guido Giunti, Richard Goossens, and Marijke Melles

Subjects
Computer applications to medicine. Medical informatics, R858-859.7, Public aspects of medicine, RA1-1270
Abstract

BackgroundThe increasing prevalence of DH applications has outpaced research and practice in digital health (DH) evaluations. Patient experience (PEx) was reported as one of the challenges facing the health system by the World Health Organization. To generate evidence on DH and promote the appropriate integration and use of technologies, a standard evaluation of PEx in DH is required. ObjectiveThis study aims to systematically identify evaluation timing considerations (ie, when to measure), evaluation indicators (ie, what to measure), and evaluation approaches (ie, how to measure) with regard to digital PEx. The overall aim of this study is to generate an evaluation guide for further improving digital PEx evaluation. MethodsThis is a 2-phase study parallel to our previous study. In phase 1, literature reviews related to PEx in DH were systematically searched from Scopus, PubMed, and Web of Science databases. Two independent raters conducted 2 rounds of paper screening, including title and abstract screening and full-text screening, and assessed the interrater reliability for 20% (round 1: 23/115 and round 2: 12/58) random samples using the Fleiss-Cohen coefficient (round 1: k1=0.88 and round 2: k2=0.80). When reaching interrater reliability (k>0.60), TW conducted the rest of the screening process, leaving any uncertainties for group discussions. Overall, 38% (45/119) of the articles were considered eligible for further thematic analysis. In phase 2, to check if there were any meaningful novel insights that would change our conclusions, we performed an updated literature search in which we collected 294 newly published reviews, of which 102 (34.7%) were identified as eligible articles. We considered them to have no important changes to our original results on the research objectives. Therefore, they were not integrated into the synthesis of this review and were used as supplementary materials. ResultsOur review highlights 5 typical evaluation objectives that serve 5 stakeholder groups separately. We identified a set of key evaluation timing considerations and classified them into 3 categories: intervention maturity stages, timing of the evaluation, and timing of data collection. Information on evaluation indicators of digital PEx was identified and summarized into 3 categories (intervention outputs, patient outcomes, and health care system impact), 9 themes, and 22 subthemes. A set of evaluation theories, common study designs, data collection methods and instruments, and data analysis approaches was captured, which can be used or adapted to evaluate digital PEx. ConclusionsOur findings enabled us to generate an evaluation guide to help DH intervention researchers, designers, developers, and program evaluators evaluate digital PEx. Finally, we propose 6 directions for encouraging further digital PEx evaluation research and practice to address the challenge of poor PEx.

Published
2024
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124. Confronting solutions of the Gallium Anomaly with reactor rate data

Author

Carlo Giunti and Christoph A. Ternes

Subjects
Physics, QC1-999
Abstract

Recently, several models have been suggested to reduce the tension between Gallium and reactor antineutrino spectral ratio data which is found in the framework of 3+1 active-sterile neutrino mixing. Among these models, we consider the extensions of 3+1 mixing with a finite wavepacket size, or the decay of the heaviest neutrino ν4, or the possibility to have a broad ν4 mass distribution. We consider the reactor antineutrino rate data and we show that these models cannot eliminate the tension between Gallium and reactor rate data that is found in the 3+1 neutrino mixing framework. Indeed, we show that the parameter goodness of fit remains small. We consider also a model which explains the Gallium Anomaly with non-standard decoherence in the framework of three-neutrino mixing. We find that it is compatible with the reactor rate data.

Published
2024
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126. Case report: First isolation of Yersinia pseudotuberculosis from the blood of a cat

Author

Raffaele Scarpellini, Massimo Giunti, Cecilia Bulgarelli, Elisabetta Mondo, Erika Esposito, Giammarco Assirelli, and Silvia Piva

Subjects
Yersinia pseudotuberculosis, bloodstream infection, feline, bacterial, blood, yersiniosis, Veterinary medicine, SF600-1100
Abstract

A 14-year-old female domestic short-haired cat with a diagnosed diabetes mellitus and acromegaly was presented for lethargy and dysorexia. On clinical presentation, the patient showed hyperglycemia, hyperthermia, dull mentation, and dehydration. With the suspicion of an inflammatory or infectious complication of diabetes, she was hospitalized with constant rate infusion of insulin, and empirical ampicillin sulbactam was started. Blood culture revealed positivity for Yersinia pseudotuberculosis and the septic picture was confirmed by blood analysis, with leukocytosis, neutrophilia, and an increased serum amyloid A concentration. The isolated Y. pseudotuberculosis strain showed susceptibility to every antimicrobial tested. During the second day of hospitalization, the onset of hypoglycemia and hypotension was treated with norepinephrine and glucose in fluid therapy. The cat recovered well and was discharged with insulin and amoxicillin-clavulanate. This is the first case of septicemia associated with Y. pseudotuberculosis in a cat, suspected of developing the infection after contact with natural reservoirs such as rodents or birds. This route of transmission should be highlighted especially in relation to the zoonotic potential of the bacteria.

Published
2024
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127. Observation of a sudden cessation of a very-high-energy gamma-ray flare in PKS 1510-089 with H.E.S.S. and MAGIC in May 2016

Author

Collaboration, H. E. S. S., Abdalla, H., Adam, R., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arcaro, C., Arm, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Martins, V. Barbosa, Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., Bonnefoy, S., de Lavergne, M. de Bony, Bregeon, J., Breuhaus, M., Brun, F., Brun, P., Bryan, M., Büchele, M., Bulik, T., Bylund, T., Caroff, S., Carosi, A., Casanova, S., Ch, T., Ch, S., Chen, A., Cotter, G., Curyło, M., Mbarubucyeye, J. Damascene, Davids, I. D., Davies, J., Deil, C., Devin, J., deWilt, P., Dirson, L., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Dyks, J., Egberts, K., Eichhorn, F., Einecke, S., Emery, G., Ernenwein, J. -P., Feijen, K., Fegan, S., Fiasson, A., de Clairfontaine, G. Fichet, Filipovic, M., Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Gottschall, D., Grondin, M. -H., Hahn, J., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huber, D., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kastendieck, M. A., Katarzyński, K., Katz, U., Khangulyan, D., Khélifi, B., Klepser, S., Kluźniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Mar, V., Marchegiani, P., Marcowith, A., Mares, A., Martí-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Meyer, M., Mitchell, A. M. W., Moderski, R., Mohamed, M., Mohrmann, L., Montanari, A., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, K., Nayerhoda, A., de Naurois, M., Ndiyavala, H., Niederwanger, F., Niemiec, J., Oakes, L., O'Brien, P., Odaka, H., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Panter, M., Panny, S., Parsons, R. D., Peron, G., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. Priyana, Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Raab, S., Rauth, R., Reichherzer, P., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Sailer, S., Sanchez, D. A., Santangelo, A., Sasaki, M., Scalici, M., Schüssler, F., Schutte, H. M., Schwanke, U., Schwemmer, S., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, Ł., Sun, L., Steenkamp, R., Stegmann, C., Steinmassl, S., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Vincent, P., Vink, J., Völk, H. J., Vuillaume, T., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Wong, Yu Wun, Yusafzai, A., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S. J., Zorn, J., Zouari, S., Żywucka, N., Collaboration, MAGIC, Acciari, V. A., Ansoldi, S., Antonelli, L. A., Engels, A. Arbet, Asano, K., Baack, D., Babić, A., Baquero, A., de Almeida, U. Barres, Barrio, J. A., González, J. Becerra, Bednarek, W., Bellizzi, L., Bernardini, E., Berti, A., Besenrieder, J., Bhattacharyya, W., Bigongiari, C., Bil, A., Blanch, O., Bonnoli, G., Bošnjak, Ž., Busetto, G., Carosi, R., Ceribella, G., Cerruti, M., Chai, Y., Chilingarian, A., Cikota, S., Colak, S. M., Colin, U., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., D'Amico, G., D'Elia, V., Da Vela, P., Dazzi, F., De Angelis, A., De Lotto, B., Delfino, M., Delgado, J., Depaoli, D., Di Pierro, F., Di Venere, L., neira, E. Do Souto Espi\, Prester, D. Dominis, Donini, A., Dorner, D., Doro, M., Elsaesser, D., Ramazani, V. Fallah, Fattorini, A., Ferrara, G., Foffano, L., Fonseca, M. V., Font, L., Fruck, C., Fukami, S., López, R. J. García, Garczarczyk, M., Gasparyan, S., Gaug, M., Giglietto, N., Giordano, F., Gliwny, P., Godinović, N., Green, D., Hadasch, D., Hahn, A., Heckmann, L., Herrera, J., Hoang, J., Hrupec, D., Hütten, M., Inada, T., Inoue, S., Ishio, K., Iwamura, Y., Jouvin, L., Kajiwara, Y., Karjalainen, M., Kerszberg, D., Kobayashi, Y., Kubo, H., Kushida, J., Lamastra, A., Lelas, D., Leone, F., Lindfors, E., Lombardi, S., Longo, F., López, M., López-Coto, R., López-Oramas, A., Loporchio, S., Fraga, B. Machado de Oliveira, Maggio, C., Majumdar, P., Makariev, M., Mallamaci, M., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Mariotti, M., Martínez, M., Mazin, D., Mender, S., Mićanović, S., Miceli, D., Miener, T., Minev, M., Mir, J. M., Mirzoyan, R., Molina, E., Moralejo, A., Morcuende, D., Moreno, V., Moretti, E., Munar-Adrover, P., Neustroev, V., Nigro, C., Nilsson, K., Ninci, D., Nishijima, K., Noda, K., Nozaki, S., Ohtani, Y., Oka, T., Otero-Santos, J., Palatiello, M., Paneque, D., Paoletti, R., Paredes, J. M., Pavletić, L., nil, P. Pe\, Perennes, C., Persic, M., Moroni, P. G. Prada, Pr, E., Priyadarshi, C., Puljak, I., Rhode, W., Ribó, M., Rico, J., Righi, C., Rugliancich, A., Saha, L., Sahakyan, N., Saito, T., Sakurai, S., Satalecka, K., Schleicher, B., Schmidt, K., Schweizer, T., Sitarek, J., Šnidarić, I., Sobczynska, D., Spolon, A., Stamerra, A., Strom, D., Strzys, M., Suda, Y., Surić, T., Takahashi, M., Tavecchio, F., Temnikov, P., Terzić, T., Teshima, M., Torres-Albà, N., Tosti, L., Truzzi, S., van Scherpenberg, J., Vanzo, G., Acosta, M. Vazquez, Ventura, S., Verguilov, V., Vigorito, C. F., Vitale, V., Vovk, I., Will, M., Zarić, D., Jorstad, S. G., Marscher, A. P., Boccardi, B., Casadio, C., Hodgson, J., Kim, J. -Y., Krichbaum, T. P., Lähteenmäki, A., Tornikoski, M., Traianou, E., and Weaver, Z. R.

Subjects
Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Astrophysics of Galaxies
Abstract

The flat spectrum radio quasar (FSRQ) PKS 1510-089 is known for its complex multiwavelength behavior, and is one of only a few FSRQs detected at very high energy (VHE, $E>100\,$GeV) $\gamma$-rays. VHE $\gamma$-ray observations with H.E.S.S. and MAGIC during late May and early June 2016 resulted in the detection of an unprecedented flare, which reveals for the first time VHE $\gamma$-ray intranight variability in this source. While a common variability timescale of $1.5\,$hr is found, there is a significant deviation near the end of the flare with a timescale of $\sim 20\,$min marking the cessation of the event. The peak flux is nearly two orders of magnitude above the low-level emission. For the first time, curvature is detected in the VHE $\gamma$-ray spectrum of PKS 1510-089, which is fully explained through absorption by the extragalactic background light. Optical R-band observations with ATOM reveal a counterpart of the $\gamma$-ray flare, even though the detailed flux evolution differs from the VHE ightcurve. Interestingly, a steep flux decrease is observed at the same time as the cessation of the VHE flare. In the high energy (HE, $E>100\,$MeV) $\gamma$-ray band only a moderate flux increase is observed with Fermi-LAT, while the HE $\gamma$-ray spectrum significantly hardens up to a photon index of 1.6. A search for broad-line region (BLR) absorption features in the $\gamma$-ray spectrum indicates that the emission region is located outside of the BLR. Radio VLBI observations reveal a fast moving knot interacting with a standing jet feature around the time of the flare. As the standing feature is located $\sim 50\,$pc from the black hole, the emission region of the flare may have been located at a significant distance from the black hole. If this correlation is indeed true, VHE $\gamma$ rays have been produced far down the jet where turbulent plasma crosses a standing shock., Comment: 25 pages, 17 figures. Accepted for publication by Astronomy & Astrophysics. Corresponding authors: M. Zacharias, J. Sitarek, D. Sanchez, T. Terzic

Published
2020
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128. A Standard Model explanation for the MiniBooNE anomaly

Author

Ioannisian, Ara, Giunti, Carlo, and Ranucci, Gioacchino

Subjects
High Energy Physics - Phenomenology
Abstract

We present the results of a new analysis of the data of the MiniBooNE experiment taking into account the additional background of photons. MiniBooNE normalises the rate of photon production to the measured $\pi^0$ production rate. We study neutral current (NC) neutrino-induced $\pi^0$/photon production ($\nu_\mu + A \to \nu_\mu +1\pi^0 / \gamma + X$) on carbon nucleus (A=12). Our conclusion is based on experimental data for photon-nucleus interactions from the A2 collaboration at the Mainz MAMI accelerator. We work in the approximation that decays of the intermediate states (non-resonant N, $\Delta$ resonance, higher resonances) unaffected by its production channel, via photon or Z boson. $1\pi^0+X$ production scales as A$^{2/3}$, the surface area of the nucleus. Meanwhile the photons incoherently created in intermediate states decays will leave the nucleus, and that cross section will be proportional to the atomic number of the nucleus. We also took into account the coherent emission of photons. We show that the new photon background can explain part of the MiniBooNE low-energy excess, thus significantly lowering the number of unexplained MiniBooNE electron-like events from $5.1\sigma$ to $3.6\sigma$., Comment: Contribution to the proceedings of the 40th ICHEP2020, Prague, Czech Republic (Virtual Conference), 6 pages

Published
2020

129. Decomposing filtered chain complexes: geometry behind barcoding algorithms

Author

Chachólski, Wojciech, Giunti, Barbara, Jin, Alvin, and Landi, Claudia

Subjects
Mathematics - Algebraic Topology, 55N31
Abstract

In Topological Data Analysis, filtered chain complexes enter the persistence pipeline between the initial filtering of data and the final persistence invariants extraction. It is known that they admit a tame class of indecomposables, called interval spheres. In this paper, we provide an algorithm to decompose filtered chain complexes into such interval spheres. This algorithm provides geometric insights into various aspects of the standard persistence algorithm and two of its run-time optimizations. Moreover, since it works for any filtered chain complexes, our algorithm can be applied in more general cases. As an application, we show how to decompose filtered kernels with it., Comment: Revised version, decomposition of filtered kernels added

Published
2020

130. Quantitative homogenization of interacting particle systems

Author

Giunti, Arianna, Gu, Chenlin, and Mourrat, Jean-Christophe

Subjects
Mathematics - Probability, Mathematics - Analysis of PDEs, 82C22, 35B27, 60K35
Abstract

For a class of interacting particle systems in continuous space, we show that finite-volume approximations of the bulk diffusion matrix converge at an algebraic rate. The models we consider are reversible with respect to the Poisson measures with constant density, and are of non-gradient type. Our approach is inspired by recent progress in the quantitative homogenization of elliptic equations. Along the way, we develop suitable modifications of the Caccioppoli and multiscale Poincar\'e inequalities, which are of independent interest., Comment: 60 pages, 6 figures; a new section is added to the appendix

Published
2020

131. An extreme particle accelerator in the Galactic plane: HESS J1826$-$130

Author

Collaboration, H. E. S. S., Abdalla, H., Adam, R., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Martins, V. Barbosa, Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Bi, B., Böttcher, M., Boisson, C., Bolmont, J., de Lavergne, M. de Bony, Bordas, P., Breuhaus, M., Brun, F., Brun, P., Bryan, M., Büchele, M., Bulik, T., Bylund, T., Caroff, S., Carosi, A., Casanova, S., Chand, T., Chandra, S., Chen, A., Cotter, G., Curyło, M., Mbarubucyeye, J. Damascene, Davids, I. D., Davies, J., Deil, C., Devin, J., deWilt, P., Dirson, L., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Duffy, C., Dyks, J., Egberts, K., Eichhorn, F., Einecke, S., Emery, G., Ernenwein, J. -P., Feijen, K., Fegan, S., Fiasson, A., de Clairfontaine, G. Fichet, Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Gottschall, D., Grondin, M. -H., Hahn, J., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huber, D., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kasai, E., Kastendieck, M. A., Katarzyński, K., Katz, U., Khangulyan, D., Khélifi, B., Klepser, S., Kluźniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martí-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Meyer, M., Mitchell, A., Moderski, R., Mohamed, M., Mohrmann, L., Montanari, A., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, K., Nayerhoda, A., de Naurois, M., Ndiyavala, H., Niederwanger, F., Niemiec, J., Oakes, L., O'Brien, P., Odaka, H., Ohm, S., Olivera-Nieto, L., Wilhelmi, E. de Ona, Ostrowski, M., Oya, I., Panter, M., Panny, S., Parsons, R. D., Peron, G., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. Priyana, Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Raab, S., Rauth, R., Reichherzer, P., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Sailer, S., Sanchez, D. A., Santangelo, A., Sasaki, M., Scalici, M., Schüssler, F., Schutte, H. M., Schwanke, U., Schwemmer, S., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, Ł., Sun, L., Steenkamp, R., Stegmann, C., Steinmassl, S., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Vincent, P., Vink, J., Völk, H. J., Vuillaume, T., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Wong, Yu Wun, Yusafzai, A., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S. J., Ziegler, A., Zorn, J., Zouari, S., and Żywucka, N.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

The unidentified very-high-energy (VHE; E $>$ 0.1 TeV) $\gamma$-ray source, HESS J1826$-$130, was discovered with the High Energy Stereoscopic System (HESS) in the Galactic plane. The analysis of 215 h of HESS data has revealed a steady $\gamma$-ray flux from HESS J1826$-$130, which appears extended with a half-width of 0.21$^{\circ}$ $\pm$ 0.02$^{\circ}_{\text{stat}}$ $\pm$ 0.05$^{\circ}_{\text{sys}}$. The source spectrum is best fit with either a power-law function with a spectral index $\Gamma$ = 1.78 $\pm$ 0.10$_{\text{stat}}$ $\pm$ 0.20$_{\text{sys}}$ and an exponential cut-off at 15.2$^{+5.5}_{-3.2}$ TeV, or a broken power-law with $\Gamma_{1}$ = 1.96 $\pm$ 0.06$_{\text{stat}}$ $\pm$ 0.20$_{\text{sys}}$, $\Gamma_{2}$ = 3.59 $\pm$ 0.69$_{\text{stat}}$ $\pm$ 0.20$_{\text{sys}}$ for energies below and above $E_{\rm{br}}$ = 11.2 $\pm$ 2.7 TeV, respectively. The VHE flux from HESS J1826$-$130 is contaminated by the extended emission of the bright, nearby pulsar wind nebula (PWN), HESS J1825$-$137, particularly at the low end of the energy spectrum. Leptonic scenarios for the origin of HESS J1826$-$130 VHE emission related to PSR J1826$-$1256 are confronted by our spectral and morphological analysis. In a hadronic framework, taking into account the properties of dense gas regions surrounding HESS J1826$-$130, the source spectrum would imply an astrophysical object capable of accelerating the parent particle population up to $\gtrsim$200 TeV. Our results are also discussed in a multiwavelength context, accounting for both the presence of nearby supernova remnants (SNRs), molecular clouds, and counterparts detected in radio, X-rays, and TeV energies., Comment: 9 Pages, 5 Figures

Published
2020
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132. Constraints on light vector mediators through coherent elastic neutrino nucleus scattering data from COHERENT

Author

Cadeddu, M., Cargioli, N., Dordei, F., Giunti, C., Li, Y. F., Picciau, E., and Zhang, Y. Y.

Subjects
High Energy Physics - Phenomenology
Abstract

We present new constraints on three different models, the so-called universal, $B-L$ and $L_\mu-L_\tau$ models, involving a yet to be observed light vector $Z'$ mediator, by exploiting the recent observation of coherent elastic neutrino-nucleus scattering (CE$\nu$NS) in argon and cesium-iodide performed by the COHERENT Collaboration. We compare the results obtained from a combination of the above data sets with the limits derived from searches in fixed target, accelerator, solar neutrino and reactor CE$\nu$NS experiments, and with the parameter region that could explain the anomalous magnetic moment of the muon. We show that for the universal and the $B-L$ models, the COHERENT data allow us to put stringent limits in the light vector mediator mass, $M_{Z'}$, and coupling, $g_{Z'}$, parameter space., Comment: 12 pages, 5 figures, matches journal version

Published
2020
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133. Search for dark matter signals towards a selection of recently-detected DES dwarf galaxy satellites of the Milky Way with H.E.S.S

Author

Collaboration, H. E. S. S., Abdallah, H., Adam, R., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arakawa, M., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Martins, V. Barbosa, Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Böttcher, M., Boisson, C., Bolmont, J., Bonnefoy, S., Breuhaus, M., Bregeon, J., Brun, F., Brun, P., Bryan, M., Büchele, M., Bulik, T., Bylund, T., Caroff, S., Carosi, A., Casanova, S., Chand, T., Chandra, S., Chen, A., Cotter, G., Curyło, M., Davids, I. D., Davies, J., Deil, C., Devin, J., deWilt, P., Dirson, L., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Dyks, J., Egberts, K., Eichhorn, F., Emery, G., Ernenwein, J. -P., Eschbach, S., Feijen, K., Fegan, S., Fiasson, A., Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Gottschall, D., Grondin, M. -H., Hahn, J., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huber, D., Iwasaki, H., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kastendieck, M. A., Katarzyński, K., Katsuragawa, M., Katz, U., Khangulyan, D., Khélifi, B., Klepser, S., Kluźniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leser, E., Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martì-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Moderski, R., Mohamed, M., Mohrmann, L., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, K., Nakashima, S., de Naurois, M., Ndiyavala, H., Niederwanger, F., Niemiec, J., Oakes, L., O'Brien, P., Odaka, H., Ohm, S., Wilhelmi, E. de Ona, Ostrowski, M., Panter, M., Parsons, R. D., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. Priyana, Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Raab, S., Rauth, R., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Sailer, S., Saito, S., Sanchez, D. A., Santangelo, A., Sasaki, M., Scalici, M., Schüssler, F., Schutter, H. M., Schwanke, U., Schwemmer, S., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, Ł., Steenkamp, R., Stegmann, C., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tsuji, N., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Viana, A., Vincent, P., Vink, J., Völk, H. J., Vuillaume, T., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Yang, R., Yoneda, H., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S., Zorn, J., and Żywucka, N.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

Dwarf spheroidal galaxy satellites of the Milky Way are prime targets for indirect detection of dark matter with gamma rays due to their proximity, high dark matter content and absence of non-thermal emission processes. Recently, the Dark Energy Survey (DES) revealed the existence of new ultra-faint dwarf spheroidal galaxies in the southern-hemisphere sky, therefore ideally located for ground-based observations with the imaging atmospheric Cherenkov telescope array H.E.S.S. We present a search for very-high-energy ($E\gtrsim100$ GeV) gamma-ray emission using H.E.S.S. observations carried out recently towards Reticulum II, Tucana II, Tucana III, Tucana IV and Grus II satellites. No significant very-high-energy gamma-ray excess is found from the observations on any individual object nor in the combined analysis of all the datasets. Using the most recent modeling of the dark matter distribution in the dwarf galaxy halo, we compute for the first time on DES satellites individual and combined constraints from Cherenkov telescope observations on the annihilation cross section of dark matter particles in the form of Weakly Interacting Massive Particles. The combined 95% C.L. observed upper limits reach $\langle \sigma v \rangle \simeq 1 \times 10^{-23}$ cm$^3$s$^{-1}$ in the $W^+W^-$ channel and $4 \times 10^{-26}$ cm$^3$s$^{-1}$ in the $\gamma\gamma$ channels for a dark matter mass of 1.5 TeV. The H.E.S.S. constraints well complement the results from Fermi-LAT, HAWC, MAGIC and VERITAS and are currently the most stringent in the $\gamma\gamma$ channels in the multi-GeV/multi-TeV mass range., Comment: 20 pages, 12 figures

Published
2020
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134. Convergence rates for the homogenization of the Poisson problem in randomly perforated domains

Author

Giunti, Arianna

Subjects
Mathematics - Analysis of PDEs, 35B27, 35J25, 60F15, 60F99, 60G55
Abstract

In this paper we provide converge rates for the homogenization of the Poisson problem with Dirichlet boundary conditions in a randomly perforated domain of $\mathbb{R}^d$, $d \geq 3$. We assume that the holes that perforate the domain are spherical and are generated by a rescaled marked point process $(\Phi, \mathcal{R})$. The point process $\Phi$ generating the centres of the holes is either a Poisson point process or the lattice $\mathbb{Z}^d$; the marks $\mathcal{R}$ generating the radii are unbounded i.i.d random variables having finite $(d-2+\beta)$-moment, for $\beta > 0$. We study the rate of convergence to the homogenized solution in terms of the parameter $\beta$. We stress that, for certain values of $\beta$, the balls generating the holes may overlap with overwhelming probability., Comment: 37 pages, 2 figures

Published
2020

135. Sterile neutrino self-interactions: $H_0$ tension and short-baseline anomalies

Author

Archidiacono, Maria, Gariazzo, Stefano, Giunti, Carlo, Hannestad, Steen, and Tram, Thomas

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics, High Energy Physics - Phenomenology
Abstract

Sterile neutrinos with a mass in the eV range have been invoked as a possible explanation of a variety of short baseline (SBL) neutrino oscillation anomalies. However, if one considers neutrino oscillations between active and sterile neutrinos, such neutrinos would have been fully thermalised in the early universe, and would be therefore in strong conflict with cosmological bounds. In this study we first update cosmological bounds on the mass and energy density of eV-scale sterile neutrinos. We then perform an updated study of a previously proposed model in which the sterile neutrino couples to a new light pseudoscalar degree of freedom. Consistently with previous analyses, we find that the model provides a good fit to all cosmological data and allows the high value of $H_0$ measured in the local universe to be consistent with measurements of the cosmic microwave background. However, new high $\ell$ polarisation data constrain the sterile neutrino mass to be less than approximately 1 eV in this scenario. Finally, we combine the cosmological bounds on the pseudoscalar model with a Bayesian inference analysis of SBL data and conclude that only a sterile mass in narrow ranges around 1 eV remains consistent with both cosmology and SBL data., Comment: 20 pages, 6 figures, 2 tables. Accepted version will appear in JCAP

Published
2020
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136. Neutrino charge constraints from scattering to the weak gravity conjecture to neutron stars

Author

Das, Arindam, Ghosh, Diptimoy, Giunti, Carlo, and Thalapillil, Arun

Subjects
High Energy Physics - Phenomenology, Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Experiment, High Energy Physics - Theory
Abstract

In various extensions of the Standard Model of particle physics, and intriguingly even in the three-generation Standard Model without neutrino masses, neutrinos are allowed to have very tiny electric charges. After a review of the theoretical scenarios that allow the emergence of such charges, we discuss the existing observational limits and we derive new stringent direct upper bounds for the charges of the muon and tau neutrinos. We also point out a flavor-universal lower bound on neutrino charges which is obtained from the weak gravity conjecture, that is based on the hypothesis that gravity is the weakest force. We finally present a new flavor-universal upper bound on neutrino charges based on astrophysical observations of Magnetars., Comment: 9 pages. Changes in exposition and additional details. Published version

Published
2020
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137. Physics results from the first COHERENT observation of CE$\nu$NS in argon and their combination with cesium-iodide data

Author

Cadeddu, M., Dordei, F., Giunti, C., Li, Y. F., Picciau, E., and Zhang, Y. Y.

Subjects
High Energy Physics - Phenomenology
Abstract

We present the results on the radius of the neutron distribution in $^{40}\text{Ar}$, on the low-energy value of the weak mixing angle, and on the electromagnetic properties of neutrinos obtained from the analysis of the coherent neutrino-nucleus elastic scattering data in argon recently published by the COHERENT collaboration, taking into account proper radiative corrections. We present also the results of the combined analysis of the COHERENT argon and cesium-iodide data for the determination of the low-energy value of the weak mixing angle and the electromagnetic properties of neutrinos. In particular, the COHERENT argon data allow us to improve significantly the only existing laboratory bounds on the electric charge $q_{\mu\mu}$ of the muon neutrino and on the transition electric charge $q_{\mu\tau}$., Comment: 20 pages

Published
2020
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138. Probing the magnetic field in the GW170817 outflow using H.E.S.S. observations

Author

Collaboration, H. E. S. S., Abdalla, H., Adam, R., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arakawa, M., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Barbosa-Martins, V., Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Blackwell, R., Böttcher, M., Boisson, C., Bolmont, J., Bonnefoy, S., Bregeon, J., Breuhaus, M., Brun, F., Brun, P., Bryan, M., Büchele, M., Bulik, T., Bylund, T., Caroff, S., Carosi, A., Casanova, S., Cerruti, M., Chand, T., Chandra, S., Chen, A., Cotter, G., Curyło, M., Davids, I. D., Davies, J., Deil, C., Devin, J., deWilt, P., Dirson, L., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Dyks, J., Egberts, K., Eichhorn, F., Emery, G., Ernenwein, J. -P., Eschbach, S., Feijen, K., Fegan, S., Fiasson, A., Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Gottschall, D., Grondin, M. -H., Hahn, J., Haupt, M., Heinzelmann, G., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huber, D., Iwasaki, H., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kastendieck, M. A., Katarzyński, K., Katsuragawa, M., Katz, U., Khangulyan, D., Khélifi, B., Klepser, S., Kluźniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leser, E., Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martí-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Moderski, R., Mohamed, M., Mohrmann, L., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, S., Nakashima, K., de Naurois, M., Ndiyavala, H., Niederwanger, F., Niemiec, J., Oakes, L., O'Brien, P., Odaka, H., Ohm, S., Wilhelmi, E. de Ona, Ostrowski, M., Panter, M., Parsons, R. D., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. Priyana, Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Raab, S., Rauth, R., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Sailer, S., Saito, S., Sanchez, D. A., Santangelo, A., Sasaki, M., Scalici, M., Schlickeiser, R., Schüssler, F., Schulz, A., Schutte, H., Schwanke, U., Schwemmer, S., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, Ł., Steenkamp, R., Stegmann, C., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tsuji, N., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Vincent, P., Vink, J., Völk, H. J., Vuillaume, T., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Yang, R., Yoneda, H., Zacharias, M., Zanin, R., Zdziarski, A. A., Zech, A., Zorn, J., Zywucka, N., and Rodrigues, X.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

The detection of the first electromagnetic counterpart to the binary neutron star (BNS) merger remnant GW170817 established the connection between short $\gamma$-ray bursts and BNS mergers. It also confirmed the forging of heavy elements in the ejecta (a so-called kilonova) via the r-process nucleosynthesis. The appearance of non-thermal radio and X-ray emission, as well as the brightening, which lasted more than 100 days, were somewhat unexpected. Current theoretical models attempt to explain this temporal behavior as either originating from a relativistic off-axis jet or a kilonova-like outflow. In either scenario, there is some ambiguity regarding how much energy is transported in the non-thermal electrons versus the magnetic field of the emission region. Combining the VLA (radio) and Chandra (X-ray) measurements with observations in the GeV-TeV domain can help break this ambiguity, almost independently of the assumed origin of the emission. Here we report for the first time on deep H.E.S.S. observations of GW170817 / GRB 170817A between 124 and 272 days after the BNS merger with the full H.E.S.S. array of telescopes, as well as on an updated analysis of the prompt (<5 days) observations with the upgraded H.E.S.S. phase-I telescopes. We discuss implications of the H.E.S.S. measurement for the magnetic field in the context of different source scenarios., Comment: 7 pages, 2 figures, 1 table

Published
2020
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139. Statistical Significance of Reactor Antineutrino Active-Sterile Oscillations

Author

Giunti, C.

Subjects
High Energy Physics - Phenomenology, High Energy Physics - Experiment
Abstract

We performed Monte Carlo calculations of the statistical distribution of the $\chi^2$ test statistic used in the analysis of the data of the NEOS, DANSS, Bugey-3, and PROSPECT short-baseline reactor experiments. We show that the statistical significance of the NEOS and DANSS indications in favor of active-sterile neutrino oscillations is smaller than that obtained with the usual method based on the $\chi^2$ distribution. In the combined analysis of the data of the four experiments we find that the statistical significance of active-sterile neutrino oscillations is reduced from $2.4\sigma$ to $1.8\sigma$., Comment: 6 pages. Final version to be published in Phys. Rev. D

Published
2020
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140. Very high energy $\gamma$-ray emission from two blazars of unknown redshift and upper limits on their distance

Author

Collaboration, H. E. S. S., Abdalla, H., Adam, R., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arakawa, M., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Baghmanyan, V., Martins, V. Barbosa, Barnacka, A., Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Böttcher, M., Boisson, C., Bolmont, J., Bonnefoy, S., Bregeon, J., Breuhaus, M., Brun, F., Brun, P., Bryan, M., Büchele, M., Bulik, T., Bylund, T., Caroff, S., Carosi, A., Casanova, S., Chand, T., Chandra, S., Chen, A., Cotter, G., Curyło, M., Davids, I. D., Davies, J., Deil, C., Devin, J., deWilt, P., Dirson, L., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Dyks, J., Egberts, K., Eichhorn, F., Emery, G., Ernenwein, J. -P., Feijen, K., Fegan, S., Fiasson, A., Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Gottschall, D., Grondin, M. -H., Hahn, J., Haupt, M., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., H{\"}orbe, M., Horns, D., Huber, D., Iwasaki, H., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kastendieck, M. A., Katarzynski, K., Katsuragawa, M., Katz, U., Khangulyan, D., Khélifi, B., Klepser, S., Kluzniak, W., Komin, Nu., Konno, R., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leser, E., Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martí-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Moderski, R., Mohamed, M., Mohrmann, L., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, S., Nakashima, K., de Naurois, M., Ndiyavala, H., Niederwanger, F., Niemiec, J., Oakes, L., O'Brien, P., Odaka, H., Ohm, S., Wilhelmi, E. de Ona, Ostrowski, M., Panter, M., Parsons, R. D., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. Priyana, Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Raab, S., Rauth, R., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Sailer, S., Saito, S., Sanchez, D. A., Santangelo, A., Sasaki, M., Scalici, M., Schüssler, F., Schutte, H. M., Schwanke, U., Schwemmer, S., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, Ł., Steenkamp, R., Stegmann, C., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tsuji, N., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Vincent, P., Vink, J., Völk, H. J., Vuillaume, T., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Yang, R., Yoneda, H., Zacharias, M., Zanin, R., Zargaryan, D., Zdziarski, A. A., Zech, A., Zhu, S. J., Zorn, J., Żywucka, N., and Cerruti, M.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

We report on the detection of very-high-energy (VHE; $E > 100$ GeV) $\gamma$-ray emission from the BL Lac objects KUV 00311-1938 and PKS 1440-389 with the High Energy Stereoscopic System (H.E.S.S.). H.E.S.S. observations were accompanied or preceded by multi-wavelength observations with Fermi/LAT, XRT and UVOT on board the Swift satellite, and ATOM. Based on an extrapolation of the Fermi/LAT spectrum towards the VHE $\gamma$-ray regime, we deduce a 95% confidence level upper limit on the unknown redshift of KUV 00311-1938 of z < 0.98, and of PKS 1440-389 of z < 0.53. When combined with previous spectroscopy results the redshift of KUV 00311-1938 is constrained to $0.51 \leq z < 0.98$ and for PKS 1440-389 to $0.14 \lessapprox z < 0.53$., Comment: Accepted for publication in MNRAS. 13 pages, 4 figures

Published
2020
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141. Invariants for tame parametrised chain complexes

Author

Chachólski, Wojciech, Giunti, Barbara, and Landi, Claudia

Subjects
Mathematics - Algebraic Topology, 55PXX, 55N31
Abstract

We set the foundations for a new approach to Topological Data Analysis (TDA) based on homotopical methods at chain complexes level. We present the category of tame parametrised chain complexes as a comprehensive environment that includes several cases that usually TDA handles separately, such as persistence modules, zigzag modules, and commutative ladders. We extract new invariants in this category using a model structure and various minimal cofibrant approximations. Such approximations and their invariants retain some of the topological, and not just homological, aspects of the objects they approximate.

Published
2020

142. Convergence of the pressure in the homogenization of the Stokes equations in randomly perforated domains

Author

Giunti, Arianna and Höfer, Richard M.

Subjects
Mathematics - Analysis of PDEs
Abstract

We consider the homogenization to the Brinkman equations for the incompressible Stokes equations in a bounded domain which is perforated by a random collection of small spherical holes. This problem has been studied by the same authors in [A. Giunti and R.M. H\"ofer, Homogenization for the Stokes equations in randomly perforated domains under almost minimal assumptions on the size of the holes] where convergence of the fluid velocity field towards the solution of the Brinkman equations has been established. In the present we consider the pressure associated to the solution of the Stokes equations in the perforated domain. We prove that it is possible to extend this pressure inside the holes and slightly modify it in a region of asymptotically negligible harmonic capacity such that it weakly converges to the pressure associated with the solution of the Brinkman equations., Comment: 14 pages. arXiv admin note: text overlap with arXiv:1809.04491

Published
2020

143. Detection of very-high-energy {\gamma}-ray emission from the colliding wind binary {\eta} Car with H.E.S.S

Author

Collaboration, H. E. S. S., Abdalla, H., Adam, R., Aharonian, F., Benkhali, F. Ait, Angüner, E. O., Arakawa, M., Arcaro, C., Armand, C., Armstrong, T., Ashkar, H., Backes, M., Martins, V. Barbosa, Barnard, M., Becherini, Y., Berge, D., Bernlöhr, K., Blackwell, R., Böttcher, M., Boisson, C., Bolmont, J., Bonnefoy, S., Bregeon, J., Breuhaus, M., Brun, F., Brun, P., Bryan, M., Büchele, M., Bulik, T., Bylund, T., Caroff, S., Carosi, A., Casanova, S., Cerruti, M., Chand, T., Chandra, S., Chen, A., Colafrancesco, S., Cotter, G., Curyło, M., Davids, I. D., Davies, J., Deil, C., Devin, J., deWilt, P., Dirson, L., Djannati-Ataï, A., Dmytriiev, A., Donath, A., Doroshenko, V., Dyks, J., Egberts, K., Eichhorn, F., Emery, G., Ernenwein, J. -P., Eschbach, S., Feijen, K., Fegan, S., Fiasson, A., Fontaine, G., Funk, S., Füßling, M., Gabici, S., Gallant, Y. A., Gaté, F., Giavitto, G., Giunti, L., Glawion, D., Glicenstein, J. F., Gottschall, D., Grondin, M. -H., Hahn, J., Haupt, M., Heinzelmann, G., Henri, G., Hermann, G., Hinton, J. A., Hofmann, W., Hoischen, C., Holch, T. L., Holler, M., Hörbe, M., Horns, D., Huber, D., Iwasaki, H., Jamrozy, M., Jankowsky, D., Jankowsky, F., Jardin-Blicq, A., Joshi, V., Jung-Richardt, I., Kastendieck, M. A., Katarzyński, K., Katsuragawa, M., Katz, U., Khangulyan, D., Khélifi, B., King, J., Klepser, S., Kluźniak, W., Komin, Nu., Kosack, K., Kostunin, D., Kreter, M., Lamanna, G., Lemière, A., Lemoine-Goumard, M., Lenain, J. -P., Leser, E., Levy, C., Lohse, T., Lypova, I., Mackey, J., Majumdar, J., Malyshev, D., Marandon, V., Marchegiani, P., Marcowith, A., Mares, A., Martí-Devesa, G., Marx, R., Maurin, G., Meintjes, P. J., Moderski, R., Mohamed, M., Mohrmann, L., Moore, C., Morris, P., Moulin, E., Muller, J., Murach, T., Nakashima, S., Nakashima, K., de Naurois, M., Ndiyavala, H., Niederwanger, F., Niemiec, J., Oakes, L., O'Brien, P., Odaka, H., Ohm, S., Wilhelmi, E. de Ona, Ostrowski, M., Panter, M., Parsons, R. D., Perennes, C., Petrucci, P. -O., Peyaud, B., Piel, Q., Pita, S., Poireau, V., Noel, A. Priyana, Prokhorov, D. A., Prokoph, H., Pühlhofer, G., Punch, M., Quirrenbach, A., Raab, S., Rauth, R., Reimer, A., Reimer, O., Remy, Q., Renaud, M., Rieger, F., Rinchiuso, L., Romoli, C., Rowell, G., Rudak, B., Ruiz-Velasco, E., Sahakian, V., Sailer, S., Saito, S., Sanchez, D. A., Santangelo, A., Sasaki, M., Scalici, M., Schlickeiser, R., Schüssler, F., Schulz, A., Schutte, H. M., Schwanke, U., Schwemmer, S., Seglar-Arroyo, M., Senniappan, M., Seyffert, A. S., Shafi, N., Shiningayamwe, K., Simoni, R., Sinha, A., Sol, H., Specovius, A., Spencer, S., Spir-Jacob, M., Stawarz, Ł., Steenkamp, R., Stegmann, C., Steppa, C., Takahashi, T., Tavernier, T., Taylor, A. M., Terrier, R., Tiziani, D., Tluczykont, M., Tomankova, L., Trichard, C., Tsirou, M., Tsuji, N., Tuffs, R., Uchiyama, Y., van der Walt, D. J., van Eldik, C., van Rensburg, C., van Soelen, B., Vasileiadis, G., Veh, J., Venter, C., Vincent, P., Vink, J., Völk, H. J., Vuillaume, T., Wadiasingh, Z., Wagner, S. J., Watson, J., Werner, F., White, R., Wierzcholska, A., Yang, R., Yoneda, H., Zacharias, M., Zanin, R., Zdziarski, A. A., Zech, A., Zorn, J., and Zywucka, N.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

Aims. Colliding wind binary systems have long been suspected to be high-energy (HE; 100 MeV < E < 100 GeV) {\gamma}-ray emitters. {\eta} Car is the most prominent member of this object class and is confirmed to emit phase-locked HE {\gamma} rays from hundreds of MeV to ~100 GeV energies. This work aims to search for and characterise the very-high-energy (VHE; E >100 GeV) {\gamma}-ray emission from {\eta} Car around the last periastron passage in 2014 with the ground-based High Energy Stereoscopic System (H.E.S.S.). Methods. The region around {\eta} Car was observed with H.E.S.S. between orbital phase p = 0.78 - 1.10, with a closer sampling at p {\approx} 0.95 and p {\approx} 1.10 (assuming a period of 2023 days). Optimised hardware settings as well as adjustments to the data reduction, reconstruction, and signal selection were needed to suppress and take into account the strong, extended, and inhomogeneous night sky background (NSB) in the {\eta} Car field of view. Tailored run-wise Monte-Carlo simulations (RWS) were required to accurately treat the additional noise from NSB photons in the instrument response functions. Results. H.E.S.S. detected VHE {\gamma}-ray emission from the direction of {\eta} Car shortly before and after the minimum in the X-ray light-curve close to periastron. Using the point spread function provided by RWS, the reconstructed signal is point-like and the spectrum is best described by a power law. The overall flux and spectral index in VHE {\gamma} rays agree within statistical and systematic errors before and after periastron. The {\gamma}-ray spectrum extends up to at least ~400 GeV. This implies a maximum magnetic field in a leptonic scenario in the emission region of 0.5 Gauss. No indication for phase-locked flux variations is detected in the H.E.S.S. data., Comment: 9 pages, 4 figures, 3 tables, in press with A&A

Published
2020
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144. Constraints on neutrino millicharge and charge radius from neutrino-atom scattering

Author

Cadeddu, Matteo, Giunti, Carlo, Kouzakov, Konstantin A., Li, Yufeng, Studenikin, Alexander I., and Zhang, Yiyu

Subjects
High Energy Physics - Phenomenology, Astrophysics - High Energy Astrophysical Phenomena
Abstract

We consider possible effects of neutrino electric charge (millicharge) and charge radius on the neutrino-atom interaction processes such as (i) atomic ionization by neutrino impact and (ii) coherent elastic neutrino-nucleus scattering. The bounds on the neutrino millicharge and charge radius that follow from, respectively, the GEMMA and COHERENT experiments are presented and discussed., Comment: 3 pages in LaTex, to appear in the proceedings of the European Physical Society Conference on High Energy Physics - EPS-HEP2019 - 10-17 July, 2019, Ghent, Belgium

Published
2020

148. Dynamical Phenomena and Their Models: Truth and Empirical Correctness

Author

Giunti, Marco

Subjects
Empiricism -- Analysis, Semantics -- Analysis, Science and technology
Abstract

In the epistemological tradition, there are two main interpretations of the semantic relation that an empirical theory may bear to the real world. According to realism, the theory-world relationship should be conceived as truth; according to instrumentalism, instead, it should be limited to empirical adequacy. Then, depending on how empirical theories are conceived, either syntactically as a class of sentences, or semantically as a class of models, the concepts of truth and empirical adequacy assume different and specific forms. In this paper, we review two main conceptions of truth (one sentence-based and one model-based) and two of empirical adequacy (one sentence-based and one model-based), we point out their respective difficulties, and we give a first formulation of a new general view of the theory-world relationship, which we call Methodological Constructive Realism (MCR). We then show how the content of MCR can be further specified and expressed in a definite and precise form. The bulk of the paper shows in detail how it is possible to accomplish this goal for the special case of deterministic dynamical phenomena and their correlated deterministic models. This special version of MCR is formulated as an axiomatic extension of set theory, whose specific axioms constitute a formal ontology that provides an adequate framework for analyzing the two semantic relations of truth and empirical correctness, as well as their connections., Author(s): Marco Giunti [sup.1] Author Affiliations: (1) grid.7763.5, 0000 0004 1755 3242, ALOPHIS-Applied LOgic Philosophy and HIstory of Science, Dipartimento di Pedagogia Psicologia Filosofia, Università di Cagliari, , via Is [...]

Published
2023
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149. Pathological variants in TOP3A cause distinct disorders of mitochondrial and nuclear genome stability

Author

Direnis Erdinc, Alejandro Rodríguez‐Luis, Mahmoud R Fassad, Sarah Mackenzie, Christopher M Watson, Sebastian Valenzuela, Xie Xie, Katja E Menger, Kate Sergeant, Kate Craig, Sila Hopton, Gavin Falkous, Genomics England Research Consortium, Joanna Poulton, Hector Garcia‐Moreno, Paola Giunti, Carlos A de Moura Aschoff, Jonas A Morales Saute, Amelia J Kirby, Camilo Toro, Lynne Wolfe, Danica Novacic, Lior Greenbaum, Aviva Eliyahu, Ortal Barel, Yair Anikster, Robert McFarland, Gráinne S Gorman, Andrew M Schaefer, Claes M Gustafsson, Robert W Taylor, Maria Falkenberg, and Thomas J Nicholls

Subjects
Bloom syndrome, mitochondrial disease, mtDNA, TOP3A, Medicine (General), R5-920, Genetics, QH426-470
Abstract

Abstract Topoisomerase 3α (TOP3A) is an enzyme that removes torsional strain and interlinks between DNA molecules. TOP3A localises to both the nucleus and mitochondria, with the two isoforms playing specialised roles in DNA recombination and replication respectively. Pathogenic variants in TOP3A can cause a disorder similar to Bloom syndrome, which results from bi‐allelic pathogenic variants in BLM, encoding a nuclear‐binding partner of TOP3A. In this work, we describe 11 individuals from 9 families with an adult‐onset mitochondrial disease resulting from bi‐allelic TOP3A gene variants. The majority of patients have a consistent clinical phenotype characterised by bilateral ptosis, ophthalmoplegia, myopathy and axonal sensory‐motor neuropathy. We present a comprehensive characterisation of the effect of TOP3A variants, from individuals with mitochondrial disease and Bloom‐like syndrome, upon mtDNA maintenance and different aspects of enzyme function. Based on these results, we suggest a model whereby the overall severity of the TOP3A catalytic defect determines the clinical outcome, with milder variants causing adult‐onset mitochondrial disease and more severe variants causing a Bloom‐like syndrome with mitochondrial dysfunction in childhood.

Published
2023
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150. Improved sensitivities of ESSνSB from a two-detector fit

Author

F. Capozzi, C. Giunti, and C. A. Ternes

Subjects
Neutrino Mixing, Non-Standard Neutrino Properties, Specific BSM Phenomenology, Sterile or Heavy Neutrinos, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We discuss the improvement of the sensitivity of ESSνSB to the discovery of CP violation and to new neutrino physics which can be obtained with a two-detector fit of the data of the near and far detectors. In particular, we consider neutrino non-standard interactions generated by very heavy vector mediators, nonunitary neutrino mixing, and neutrino oscillations due to the mixing of the ordinary active neutrinos with a light sterile neutrino.

Published
2023
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