480 results on '"gyrase"'
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52. Reports from University of Belgrade Describe Recent Advances in Life Science (High-performance Liquid Chromatography Evaluation of Lipophilicity and Qsrr Modeling of a Series of Dual Dna Gyrase and Topoisomerase Iv Inhibitors).
53. New Antibiotics Findings from National Institute of Chemistry Described (Dynamic Profiling and Binding Affinity Prediction of Nbti Antibacterials Against Dna Gyrase Enzyme By Multidimensional Machine Learning and Molecular Dynamics Simulations).
54. New Findings in Antibiotics Described from Department of Chemistry (Development of Novel Thiazole-based Hybrids As Dna Gyrase Inhibitors: Design, Synthesis, In Silico and In Vitro Antibacterial Evaluation).
55. Structure of Escherichia coli DNA gyrase with chirally wrapped DNA supports ratchet-and-pawl mechanism for an ATP-powered supercoiling motor.
56. Researchers from Southwest University Describe Findings in Antibiotics (Unique Azolyl Acylhydrazonyl Hybridization of Aloe Emodins To Access Potential Antibacterial Agents).
57. Hokkaido University International Institute for Zoonosis Control Reports Findings in Campylobacter jejuni (Effect of WQ-3334 on Campylobacter jejuni carrying a DNA gyrase with dominant amino acid substitutions conferring quinolone resistance).
58. Central Ayurveda Research Institute Researchers Publish New Studies and Findings in the Area of Antimicrobials (Polypharmacological assessment of Amoxicillin and its analogues against the bacterial DNA gyrase B using molecular docking, DFT and...).
59. Studies Conducted at University of KwaZulu-Natal on Antimicrobials Recently Reported (Novel 4,5-dibromo-n-phenyl-1h-pyrrole-2-carboxamide Hybrids As Promising Dna Gyrase Inhibitors: Design, Synthesis and Antimicrobial Evaluation).
60. Findings from Vanderbilt University Update Knowledge of Escherichia coli (Interactions Between Gepotidacin and escherichia Coli Gyrase and Topoisomerase Iv: Genetic and Biochemical Evidence for Well-balanced Dual-targeting).
61. Researchers from Helwan University Detail New Studies and Findings in the Area of Escherichia coli (In vitro and in silico studies of enterobactin-inspired Ciprofloxacin and Fosfomycin first generation conjugates on the antibiotic resistant E....).
62. New Neisseria gonorrhoeae Study Findings Recently Were Reported by Researchers at Vanderbilt University (Target-mediated Fluoroquinolone Resistance In Neisseria Gonorrhoeae: Actions of Ciprofloxacin Against Gyrase and Topoisomerase Iv).
63. Studies from University of Technology Have Provided New Information about Life Science (Structural-based Analysis of Antibacterial Activities of Acid Condensate From Palm Kernel Shell).
64. Studies Conducted at University of Batna 1 on Antibiotics Recently Reported (Synthesis, Antimicrobial, Dft, And In Silico Pharmacokinetic Profiling of Nitroaldol Quinoline Derivatives: a Comprehensive Exploration for Designing...).
65. Studies in the Area of Drug Research Reported from Manipal College of Pharmaceutical Sciences (Identification of Potential Dna Gyrase Inhibitors: Virtual Screening, Extra-precision Docking and Molecular Dynamics Simulation Study).
66. Discovery of Furanoquinone Derivatives as a Novel Class of DNA Polymerase and Gyrase Inhibitors for MRSA Eradication in Cutaneous Infection
67. Conditional Silencing by CRISPRi Reveals the Role of DNA Gyrase in Formation of Drug-Tolerant Persister Population in Mycobacterium tuberculosis
68. Design, Synthesis, and Antibacterial Screening of Some Novel Heteroaryl-Based Ciprofloxacin Derivatives as DNA Gyrase and Topoisomerase IV Inhibitors
69. Discovery of Furanoquinone Derivatives as a Novel Class of DNA Polymerase and Gyrase Inhibitors for MRSA Eradication in Cutaneous Infection.
70. Conditional Silencing by CRISPRi Reveals the Role of DNA Gyrase in Formation of Drug-Tolerant Persister Population in Mycobacterium tuberculosis.
71. Towards Conformation-Sensitive Inhibition of Gyrase: Implications of Mechanistic Insight for the Identification and Improvement of Inhibitors
72. Reports from Louisiana State University Add New Data to Findings in Chlamydia trachomatis (Targeted Repression of topa By Crispri Reveals a Critical Function for Balanced Dna Topoisomerase I Activity In the chlamydia Trachomatis...).
73. Data on Life Science Discussed by Researchers at University of Ljubljana (Benzothiazole Dna Gyrase Inhibitors and Their Conjugates With Siderophore Mimics: Design, Synthesis and Evaluation).
74. Recent Findings from Department of Chemistry Provides New Insights into Antimicrobials (Triazolo [1,5-a]Pyrimidines As Dna Gyrase Inhibitiors: Synthesis, Antimicrobial, Activities, and In Silico Admet With Molecular Docking Studies).
75. National Institute of Pharmaceutical Education and Research Reports Findings in Antibiotics (Synthesis and Biological Evaluation of Diphenyl Ether-linked Quinolone Derivatives As Antibacterial Agents).
76. Researchers at National Research Centre Report New Data on Antibiotics (New Sulfonamide-tethered Coumarin Derivatives As Potential Dna Gyrase Inhibitors: Design, Synthesis, Antimicrobial Evaluation, and In Silico Study).
77. Findings from Al-Azhar University Broaden Understanding of Antimicrobials (Pyrano-coumarin Hybrids As Potential Antimicrobial Agents Against Mrsa Strains: Design, Synthesis, Admet, Molecular Docking Studies, As Dna Gyrase Inhibitors).
78. New Data from Kurukshetra University Illuminate Findings in Life Science [Synthesis, Spectroscopic Characterization, In Vitro Antimicrobial Activity, Antioxidant Study and Theoretical Approaches Towards Dna Gyrase, Dhfr Enzyme, Nadph Enzyme of...].
79. Research Conducted at Umm Al-Qura University Has Provided New Information about Antimicrobials (Indeno[1,2-b]Pyridin-5-one Derivatives Containing Azo Groups and Their Hydrazonal Precursors: Synthesis, Antimicrobial Profile, Dna Gyrase...).
80. Research from Universitas Padjadjaran Provide New Insights into Bacterial Infections and Mycoses (Virtual Screening and ADMET Prediction to Uncover the Potency of Flavonoids from Genus Erythrina as Antibacterial Agent through Inhibition of...).
81. New Ophthalmic Antiinfectives Findings Has Been Reported by Investigators at Assiut University (Rational Design, Synthesis, Molecular Modeling, Biological Activity, and Mechanism of Action of Polypharmacological Norfloxacin Hydroxamic Acid...).
82. Role of the Water–Metal Ion Bridge in Quinolone Interactions with Escherichia coli Gyrase
83. CryoEM structures of open dimers of gyrase A in complex with DNA illuminate mechanism of strand passage
84. The Putative De-N-acetylase DnpA Contributes to Intracellular and Biofilm-Associated Persistence of Pseudomonas aeruginosa Exposed to Fluoroquinolones
85. Molecular Structure and Dynamics of Bacterial Nucleoids
86. Discovery of dual GyrB/ParE inhibitors active against Gram-negative bacteria.
87. The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase.
88. Synthesis and anti-staphylococcal activity of novel bacterial topoisomerase inhibitors with a 5-amino-1,3-dioxane linker moiety.
89. The Putative De-<italic>N</italic>-acetylase DnpA Contributes to Intracellular and Biofilm-Associated Persistence of <italic>Pseudomonas aeruginosa</italic> Exposed to Fluoroquinolones.
90. Ubiquitous Nature of Fluoroquinolones: The Oscillation between Antibacterial and Anticancer Activities.
91. Researchers at Isfahan University of Medical Sciences Have Reported New Data on Drug Research (Novel n-a-amino Acid Spacer-conjugated Phthalimide-triazine Derivatives: Synthesis, Antimicrobial and Molecular Docking Studies).
92. Findings from King Saud University Yields New Findings on Life Science (Novel Indole Derivatives of Dihydropyrimidinone: Synthesis, Characterization, Molecular Docking and Antimicrobial Activity).
93. Studies from Brigham and Women's Hospital Have Provided New Information about Neisseria gonorrhoeae (Development of Cas13a-based Assays for Neisseria Gonorrhoeae Detection and Gyrase a Determination).
94. A Fluorescence-Based, T5 Exonuclease-Amplified DNA Cleavage Assay for Discovering Bacterial DNA Gyrase Poisons.
95. Two Classes of DNA Gyrase Inhibitors Elicit Distinct Evolutionary Trajectories Toward Resistance in Gram-Negative Pathogens (Updated September 21, 2023).
96. Research from Ohio State University Reveals New Findings on Antibiotics (Novel bacterial topoisomerase inhibitors: unique targeting activities of amide enzyme-binding motifs for tricyclic analogs).
97. Reports Outline Life Science Study Results from GITAM University (Molecular Dynamics Simulation Approach of Hybrid Chalcone-thiazole Complex Derivatives for Dna Gyrase B Inhibition: Lead Generation).
98. Reports from Acharya Nagarjuna University Highlight Recent Findings in Life Science (Synthesis, Antimicrobial Activity, and In Silico Studies of Fluoroquinolones Bearing 1,3,4-oxadiazolyl-triazole Derivatives).
99. Federal University Lokoja Researchers Provide New Data on Antimicrobials (Isolation, Characterization, Antimicrobial and Theoretical Investigation of Some Bioactive Compounds Obtained from the Bulbs of Calotropisprocera).
100. Research from Fourth Hospital of Hebei Medical University Provide New Insights into Antibiotics (Antibacterial mechanism of action and in silico molecular docking studies of Cupressus funebris essential oil against drug resistant bacterial...).
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