1,498 results on '"Vincent, I."'
Search Results
52. Prevalence and Determinants of Generalized Anxiety Disorder Symptoms in Residents of Fort McMurray 12 Months Following the 2020 Flooding
- Author
-
Ernest Owusu, Reham Shalaby, Ejemai Eboreime, Nnamdi Nkire, Mobolaji A. Lawal, Belinda Agyapong, Hannah Pazderka, Gloria Obuobi-Donkor, Medard K. Adu, Wanying Mao, Folajinmi Oluwasina, and Vincent I. O. Agyapong
- Subjects
anxiety ,flooding ,depression ,disaster ,traumatic ,Psychiatry ,RC435-571 - Abstract
BackgroundThe flood in Fort McMurray (FMM) which occurred between April 26 and May 2, 2020, is known to have displaced an estimated population of 1,500 people, and destroyed or damaged about 1,230 buildings. In all, it is estimated to have caused about $228 million in losses.ObjectiveThis study aims to identify the prevalence and determinants of likely Generalized Anxiety disorder (GAD) in among respondents 12-months after the 2020 flooding.MethodsData for the study were collected through a cross-sectional survey sent through REDCap and hosted online from the 24th of April to the 2nd of June 2021. The self-administered questionnaire was emailed to respondents using community, government, school, and occupational platforms. Demographic, flooding-related variables, and clinical data were collected. A validated instrument, the GAD-7 was used to collect information on likely GAD. Consent was implied by completing the survey forms, and the University of Alberta Health Research Ethics Committee approved the study.ResultsOf the 249 residents surveyed, 74.7% (186) respondents completed the online survey, 81.6% (80) were above 40 years, 71% (132) were in a relationship, 85.5% (159) were females, and 94.1% (175) were employed. The prevalence of likely GAD was 42.5% in our study. Predictors of likely GAD among respondents included positive employment status (OR = 30.70; 95% C.I. 2.183–423.093), prior diagnosis of depression (OR = 3.30; 95% C.I. 1.157–9.43), and the perceived need to have mental health counseling (OR = 6.28; 95% C.I. 2.553–15.45).ConclusionThis study showed that there was an increased magnitude of moderate to high anxiety symptoms among respondents following the natural disaster particularly the flood in 2020. The predictors of likely GAD include positive employment status, history of depression diagnosis, and the need to have mental health counseling. Policymakers may mitigate the rise of anxiety after flooding in vulnerable areas by addressing these and other factors.
- Published
- 2022
- Full Text
- View/download PDF
53. Text Messages in the Field of Mental Health: Rapid Review of the Reviews
- Author
-
Reham Shalaby, Medard K. Adu, Hany M. El Gindi, and Vincent I. O. Agyapong
- Subjects
text messages ,rapid review ,mental health gap ,e-mental health ,mobile health ,Psychiatry ,RC435-571 - Abstract
BackgroundWhile mental health problems constitute a worldwide concern contributing to the global rates of morbidity and mortality, conventional mental healthcare services do not meet the current needs. Text messages (TM) represent a live model that incorporates technology into health services, spanning a large number of health conditions and playing different roles that may support the current healthcare system.ObjectiveTo examine the TM services in the field of mental health, regarding their effectiveness, feasibility, acceptability, and economic evaluation in different contexts of mental health diagnoses and during critical times, when provided to individuals with mental health symptoms/disorders.MethodsThis rapid review was conducted through an online search in PubMed, Embase, PsycINFO, and Medline databases. The review targeted the review studies which examined online or mobile addiction and mental health services, utilizing TM services. The search was run from the inception up to September 30, 2021.ResultsSixty review articles met the inclusion criteria and were included in this review. All reviews were published over the last decade. The results showed that people of a young age were fairly represented, and most reviews were run over substance use disorders (SUD), including Alcohol. Most reviews examined the effectiveness outcomes of the texting service, while to a lesser extent the acceptability and feasibility, among others. Texting services were reported as effective in psychotic disorders and SUD. However, the results related to depression and anxiety were mixed. Most reviews reported a considerably high risk of bias among their included studies. High satisfaction and acceptability of the texting services were reported for patients with various mental health conditions, including those with severe mental illness.ConclusionsThis rapid review highlighted the applications, usability, benefits, and satisfaction with the TM in the field of mental health. For a higher quality of evidence, future studies should consider TM interventions in the contexts with mixed results or a dearth of literature, and during critical times, such as the COVID-19 pandemic. Policy- and decision-makers, therefore, need to further support text-based services with guided investments in interventions that were evidenced to be accepted, economic and feasible.
- Published
- 2022
- Full Text
- View/download PDF
54. Better With Ultrasound: Transcranial Doppler
- Author
-
Lau, Vincent I., Jaidka, Atul, Wiskar, Katie, Packer, Nicholas, Tang, J. Elaine, Koenig, Seth, Millington, Scott J., and Arntfield, Robert T.
- Published
- 2020
- Full Text
- View/download PDF
55. Exploring the prevalence and predictors of low resilience and likely PTSD in residents of two provinces in Canada during the 2023 wildfires
- Author
-
Adu, Medard K., primary, Shalaby, Reham, additional, Agyapong, Belinda, additional, Dias, Raquel da Luz, additional, and Agyapong, Vincent I. O., additional
- Published
- 2024
- Full Text
- View/download PDF
56. Devastating Wildfires and Mental Health: Major Depressive Disorder Prevalence and Associated Factors among Residents in Alberta and Nova Scotia, Canada
- Author
-
Mao, Wanying, primary, Shalaby, Reham, additional, Agyapong, Belinda, additional, Obuobi-Donkor, Gloria, additional, Da Luz Dias, Raquel, additional, and Agyapong, Vincent I. O., additional
- Published
- 2024
- Full Text
- View/download PDF
57. Can Your Smartphone Save A Life? A Systematic Review of Mobile-Based Interventions For Suicide Prevention
- Author
-
Jha, Smriti, primary, Jewer, Seana, additional, Agyapong, Vincent I. O., additional, and Orji, Rita, additional
- Published
- 2024
- Full Text
- View/download PDF
58. Isolation, Economic Precarity, and Previous Mental Health Issues as Predictors of PTSD Status in Females Living in Fort McMurray During COVID-19
- Author
-
Hannah Pazderka, Reham Shalaby, Ejemai Eboreime, Wanying Mao, Gloria Obuobi-Donkor, Belinda Agyapong, Folajinmi Oluwasina, Medard Kofi Adu, Ernest Owusu, Adegboyega Sapara, and Vincent I. O. Agyapong
- Subjects
trauma ,collective trauma ,precarity ,isolation ,COVID-19 ,PTSD ,Psychiatry ,RC435-571 - Abstract
ObjectivesThe COVID-19 pandemic represents an instance of collective trauma across the globe; as such, it is unique to our lifetimes. COVID-19 has made clear systemic disparities in terms of access to healthcare and economic precarity. Our objective was to examine the mental health repercussions of COVID-19 on adult females living in Fort McMurray, Canada in light of their unique circumstances and challenges.MethodTo investigate this issue, we analyzed responses gathered from an anonymous cross-section of online survey questionnaire responses gathered from females living in the Fort McMurray area (n = 159) during the COVID-19 pandemic (April 24–June 2, 2021). This included relevant demographic, mental health history, and post-traumatic stress disorder (PTSD), as well as COVID-19 data. Chi-squared analysis was used to determine outcome relevance, and binary logistic regression was employed to generate a model of susceptibility to PTSD.Results159 females completed the survey. The prevalence of putative PTSD in our sample was 40.8%. A regression analysis revealed 4 variables with significant, unique contributions to PTSD. These were: a diagnosis of depression; a diagnosis of anxiety; job loss due to COVID-19; and lack of support from family and friends. Specifically, women with a previous diagnosis of either depression or anxiety were ~4–5 times more likely to present with PTSD symptomatology in the wake of COVID-19 (OR = 3.846; 95% CI: 1.13–13.13 for depression; OR = 5.190; 95% CI: 1.42–19.00 for anxiety). Women who reported having lost their jobs as a result of the pandemic were ~5 times more likely to show evidence of probable PTSD (OR = 5.182; 95% CI: 1.08–24.85). Receiving inadequate support from family and friends made the individual approximately four times as likely to develop probable PTSD (OR = 4.258; 95% CI: 1.24–14.65), while controlling for the other variables in the regression model.ConclusionsOverall, these results support our hypothesis that volatility in factors such as social support, economic stability, and mental health work together to increase the probability of women developing PTSD in response to a collective trauma such as COVID-19.
- Published
- 2022
- Full Text
- View/download PDF
59. The Text4HealthyAging Program: An Evidence-Based Text Messaging Innovation to Support Healthy Urban Aging in Canada and Australia
- Author
-
Ejemai Eboreime, Arto Ohinmaa, Benjamin Rusak, Keri-Leigh Cassidy, Jason Morrison, Patrick McGrath, Rudolf Uher, Sandra Meier, Marie-Josee Fleury, Srividya N. Iyer, Soham Rej, Frances Batchelor, Pazit Levinger, Christa Dang, Malcolm Hopwood, Francis N. L. Acquah, Janet Dzator, Gail Tomblin Murphy, Jordan Warford, Lori Wozney, Isabelle Vedel, Jacqueline Gahagan, Olga Theou, Prosper Koto, Tara Sampalli, Susan Kirkland, Nicholas Watters, and Vincent I. O. Agyapong
- Subjects
Geriatrics ,RC952-954.6 - Abstract
Age-friendly cities are crucial to achieve the WHO goal of healthy aging. Such cities promote opportunities for health, participation, and security, thus enhancing quality of life as people age. Older people commonly experience psychosocial challenges such as anxiety, depression, substance abuse, loss of autonomy, grief, fear, and loneliness. Australian and Canadian cities continue to seek innovation to improve healthy urban aging and create more age-friendly environments for older adults. There is increasing evidence on the effectiveness and feasibility of mobile technology in health promotion and closing psychological treatment gaps. Older adults have been demonstrated to engage frequently with mobile devices, particularly text messaging. In this article, we conceptualize the Text4HealthyAging, an evidence-based text messaging innovation to support healthy urban aging in Canadian and Australian cities.
- Published
- 2022
- Full Text
- View/download PDF
60. Administration of Parenteral Vitamin C in Patients With Severe Infection: Protocol for a Systematic Review and Meta-analysis
- Author
-
Arnav Agarwal, John Basmaji, Shannon M Fernando, Fang Zhou Ge, Yingqi Xiao, Haseeb Faisal, Kimia Honarmand, Mathieu Hylands, Vincent I Lau, Kimberley Lewis, Rachel Couban, François Lamontagne, and Neill KJ Adhikari
- Subjects
Medicine ,Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
BackgroundSevere infections are characterized by inflammation and oxidative damage. Ascorbic acid (vitamin C) administration may attenuate oxidative damage and, in turn, reduce vascular endothelial injury in pulmonary and systemic vasculature. ObjectiveWe aim to describe a protocol for a living systematic review that will evaluate the effectiveness and safety of parenteral vitamin C administration in adults with severe infections, including those with COVID-19. MethodsWe searched Ovid MEDLINE, Embase, CINAHL, the Centers for Disease Control and Prevention COVID-19 database, Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov from inception to March 30, 2021, for randomized controlled trials evaluating parenteral vitamin C versus no parenteral vitamin C in hospitalized adults with severe infection. Eligible studies will include at least 1 arm involving any dose of parenteral vitamin C alone or in combination with other cointerventions and at least 1 arm not involving parenteral vitamin C. The primary outcomes of interest will include in-hospital, 30-day, and 90-day mortality. Title and abstract screening, full-text screening, data extraction, and risk of bias evaluation via a modified Risk of Bias 2.0 tool will be conducted independently and in pairs. We will perform random effects modeling for meta-analyses, in which study weights will be generated by using the inverse variance method. We will assess certainty in effect estimates by using the Grading of Recommendations Assessment, Development and Evaluation methodology. Meta-analyses will be updated iteratively as new trial evidence becomes available. ResultsAmong the 1386 citations identified as of March 30, 2021, a total of 17 eligible randomized controlled trials have been identified as of September 2021. We are in the process of updating the search strategy and associated data analyses. ConclusionsThe results will be of importance to critical care physicians and hospitalists who manage severe infection and COVID-19 in daily practice, and they may directly inform international clinical guidance. Although our systematic review will incorporate the most recent trial evidence, ongoing trials may change our confidence in the estimates of effects, thereby necessitating iterative updates in the form of a living review. Trial RegistrationPROSPERO CRD42020209187; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=209187 International Registered Report Identifier (IRRID)RR1-10.2196/33989
- Published
- 2022
- Full Text
- View/download PDF
61. Investigating the quality of HIV rapid testing practices in public antenatal health care facilities, South Africa.
- Author
-
Duduzile F Nsibande, Selamawit A Woldesenbet, Adrian Puren, Peter Barron, Vincent I Maduna, Carl Lombard, Mireille Cheyip, Mary Mogashoa, Yogan Pillay, Vuyolwethu Magasana, Trisha Ramraj, Tendesayi Kufa, Gurpreet Kindra, Ameena Goga, and Witness Chirinda
- Subjects
Medicine ,Science - Abstract
Monitoring HIV prevalence using antenatal HIV sentinel surveillance is important for efficient epidemic tracking, programme planning and resource allocation. HIV sentinel surveillance usually employs unlinked anonymous HIV testing which raises ethical, epidemiological and public health challenges in the current era of universal test and treat. The World Health Organization (WHO) recommends that countries should consider using routine prevention of mother-to-child transmission of HIV (PMTCT) data for surveillance. We audited antenatal care clinics to assess the quality of HIV rapid testing practices as the first step to assess whether South Africa is ready to utilize PMTCT programme data for antenatal HIV surveillance. In 2017, we conducted a cross-sectional survey in 360 randomly sampled antenatal care clinics using the adapted WHO Stepwise-Process-for-Improving-the-Quality-of-HIV-Rapid-Testing (SPI-RT) checklist. We calculated median percentage scores within a domain (domain-specific median score), and across all domains (overall median percentage scores). The latter was used to classify sites according to five implementation levels; (from 0:
- Published
- 2022
- Full Text
- View/download PDF
62. Apparent Lack of Benefit of Combining Repetitive Transcranial Magnetic Stimulation with Internet-Delivered Cognitive Behavior Therapy for the Treatment of Resistant Depression: Patient-Centered Randomized Controlled Pilot Trial
- Author
-
Medard Kofi Adu, Reham Shalaby, Ejemai Eboreime, Adegboyega Sapara, Mobolaji A. Lawal, Corina Chew, Shelley Daubert, Liana Urichuck, Shireen Surood, Daniel Li, Mark Snaterse, Mike Mach, Pierre Chue, Andrew J. Greenshaw, and Vincent I. O. Agyapong
- Subjects
repetitive transcranial magnetic stimulation ,treatment-resistant depression ,internet-based cognitive behavioral therapy ,MoodGYM ,major depressive disorder ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Background: Treatment-resistant depression (TRD) is considered one of the major clinical challenges in the field of psychiatry. An estimated 44% of patients with major depressive disorder (MDD) do not respond to two consecutive antidepressant therapies, and 33% do not respond to up to four antidepressants. Over 15% of all patients with MDD remain refractory to any treatment intervention. rTMS is considered a treatment option for patients with TRD. Likewise, iCBT is evidence-based, symptom-focused psychotherapy recommended for the treatment of TRD. Objective: This study aimed to evaluate the initial comparative clinical effectiveness of rTMS treatment with and without iCBT as an innovative intervention for the treatment of participants diagnosed with TRD. Methods: This study is a prospective two-arm randomized controlled trial. Overall, 78 participants diagnosed with TRD were randomized to one of two treatment interventions: rTMS sessions alone and rTMS sessions plus iCBT. Participants in each group were made to complete evaluation measures at baseline, and 6 weeks (discharge) from treatment. The primary outcome measure was baseline to six weeks change in mean score for the 17-item Hamilton depression rating scale (HAMD-17). Secondary outcomes included mean baseline to six-week changes in the Columbia suicide severity rating scale (CSSRS) for the rate of suicidal ideations, the QIDS-SR16 for subjective depression, and the EQ-5D-5L to assess the quality of health in participants. Results: A majority of the participants were females 50 (64.1%), aged ≥ 40 39 (50.0%), and had college/university education 54 (73.0%). After adjusting for the baseline scores, the study failed to find a significant difference in the changes in mean scores for participants from baseline to six weeks between the two interventions under study on the HAMD-17 scale: F (1, 53) = 0.15, p = 0.70, partial eta squared = 0.003, CSSRS; F (1, 56) = 0.04 p = 0.85, partial eta squared = 0.001, QIDS-SR16 scale; F (1, 53) = 0.04 p = 0.61, partial eta squared = 0.005, and EQ-5D-VAS; F (1, 51) = 0.46 p = 0.50, and partial eta squared = 0.009. However, there was a significant reduction in means scores at week six compared to baseline scores for the combined study population on the HAMD-17 scale (42%), CSSRS (41%), QIDS-SR16 scale (35%), and EQ-VAS scale (62%). Conclusion: This study did not find that combined treatment of TRD with rTMS + iCBT (unguided) was superior to treatment with rTMS alone. Our findings do not support the use of combined treatment of rTMS + iCBT for the management of TRD disorders.
- Published
- 2023
- Full Text
- View/download PDF
63. Early cognitive and emotional outcome after stroke is independent of discharge destination
- Author
-
Slenders, Jos P. L., Verberne, Daan P. J., Visser-Meily, Johanna M. A., Van den Berg-Vos, Renske M., Kwa, Vincent I. H., and van Heugten, Caroline M.
- Published
- 2020
- Full Text
- View/download PDF
64. Correlation between clinical and cytological parameters of dry eye among diabetics in a Nigerian tertiary hospital
- Author
-
Onyekwelu, Onyinyechukwu M., Aribaba, Olufisayo T., Onyekwelu, Vincent I., Idowu, Oluwatobi O., Salami, Monsurah O., Badmos, Kabir B., and Onakoya, Adeola O.
- Published
- 2020
- Full Text
- View/download PDF
65. Exploring the effectiveness of advertising using the guilt appeal in the food industry
- Author
-
Vincent, I., Vincent, I., Vincent, I., and Vincent, I.
- Abstract
The full text of this thesis is not available due to privacy or embargo reasons.
- Published
- 2023
66. Probiotics in hospitalized adult patients: a systematic review of economic evaluations
- Author
-
Lau, Vincent I., Rochwerg, Bram, Xie, Feng, Johnstone, Jennie, Basmaji, John, Balakumaran, Jana, Iansavichene, Alla, and Cook, Deborah J.
- Published
- 2020
- Full Text
- View/download PDF
67. Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies
- Author
-
Harkness, Kirsty, Shaw, Louise, Sword, Jane, Mohd Nor, Azlisham, Sharma, Pankaj, Kelly, Deborah, Harrington, Frances, Randall, Marc, Smith, Matthew, Mahawish, Karim, Elmarim, Abduelbaset, Esisi, Bernard, Cullen, Claire, Nallasivam, Arumug, Price, Christopher, Barry, Adrian, Roffe, Christine, Coyle, John, Hassan, Ahamad, Birns, Jonathan, Cohen, David, Sekaran, Lakshmanan, Parry-Jones, Adrian, Parry, Anthea, Hargroves, David, Proschel, Harald, Datta, Prabel, Darawil, Khaled, Manoj, Aravindakshan, Burn, Mathew, Patterson, Chris, Giallombardo, Elio, Smyth, Nigel, Mansoor, Syed, Anwar, Ijaz, Marsh, Rachel, Ispoglou, Sissi, Chadha, Dinesh, Prabhakaran, Mathuri, Meenakishundaram, Sanjeevikumar, O'Connell, Janice, Scott, Jon, Krishnamurthy, Vinodh, Aghoram, Prasanna, McCormick, Michael, Sprigg, Nikola, O'Mahony, Paul, Cooper, Martin, Choy, Lillian, Wilkinson, Peter, Leach, Simon, Caine, Sarah, Burger, Ilse, Gunathilagan, Gunaratam, Guyler, Paul, Emsley, Hedley, Davis, Michelle, Manawadu, Dulka, Pasco, Kath, Mamun, Maam, Luder, Robert, Sajid, Mahmud, Okwera, James, Warburton, Elizabeth, Saastamoinen, Kari, England, Timothy, Putterill, Janet, Flossman, Enrico, Power, Michael, Dani, Krishna, Mangion, David, Suman, Appu, Corrigan, John, Lawrence, Enas, Vahidassr, Djamil, Shakeshaft, Clare, Brown, Martin, Charidimou, Andreas, Cohen, Hannah, Banerjee, Gargi, Houlden, Henry, White, Mark, Yousry, Tarek, Flossmann, Enrico, Muir, Keith, El-Koussy, Marwan, Gratz, Pascal, Molad, Jeremy, Korczyn, Amos, Kliper, Efrat, Maeder, Philippe, Gass, Achim, Pachai, Chahin, Bracoub, Luc, Douste-Blazy, Marie-Yvonne, Fratacci, Marie Dominique, Vicaut, Eric, Sato, Shoichiro, Miwa, Kaori, Fujita, Kyohei, Ide, Toshihiro, Ma, Henry, Ly, John, Singhal, Shahoo, Chandra, Ronil, Slater, Lee-Anne, Soufan, Cathy, Moran, Christopher, Traenka, Christopher, Thilemann, Sebastian, Fladt, Joachim, Gensicke, Henrik, Bonati, Leo, Kim, Beom Joon, Han, Moon-Ku, Kang, Jihoon, Ko, Eunbin, Yang, Mi Hwa, Jang, Myung Suk, Murphy, Sean, Carty, Fiona, Akijian, Layan, Thornton, John, Schembri, Mark, Douven, Elles, Delgado-Mederos;, Raquel, Marín, Rebeca, Camps-Renom, Pol, Guisado-Alonso, Daniel, Nuñez, Fidel, Medrano-Martorell, Santiago, Merino, Elisa, Iida, Kotaro, Ikeda, Syuhei, Nishihara, Masashi, Irie, Hiroyuki, Demirelli, Derya Selcuk, Medanta, Jayesh Modi, Zerna, Charlotte, Hernández, Maria Valdés, Armitage, Paul, Heye, Anna, Muñoz-Maniega, Susana, Sakka, Eleni, Thrippleton, Michael, Dennis, Martin, Beigneux, Ysoline, Silva, Mauro, Venketasubramanian, Narayanaswamy, Ho, Shu Leung, Cheung, Raymond Tak Fai, Chan, Koon Ho, Teo, Kay Cheong, Hui, Edward, Kwan, Joseph Shiu Kwong, Chang, Richard, Tse, Man Yu, Hoi, Chu Peng, Chan, Chung Yan, Chan, Oi Ling, Cheung, Ryan Hoi Kit, Wong, Edmund Ka Ming, Leung, Kam Tat, Tsang, Suk Fung, Ip, Hing Lung, Ma, Sze Ho, Ma, Karen, Fong, Wing Chi, Li, Siu Hung, Li, Richard, Ng, Ping Wing, Wong, Kwok Kui, Liu, Wenyan, Wong, Lawrence, Ramos, Lino, De Schryver, Els, Jöbsis, Joost, van der Sande, Jaap, Brouwers, Paul, Roos, Yvo, Stam, Jan, Bakker, Stef, Verbiest, Henk, Schoonewille, Wouter, Linn, Cisca, Hertzberger, Leopold, van Gemert, Maarten, Berntsen, Paul, Hendrikse, Jeroen, Nederkoorn, Paul, Mess, Werner, Koudstaal, Peter, Leff, Alexander, Ward, Nicholas, Nachev, Parashkev, Perry, Richard, Ozkan, Hatice, Mitchell, John, Wilson, Duncan, Ambler, Gareth, Lee, Keon-Joo, Lim, Jae-Sung, Shiozawa, Masayuki, Koga, Masatoshi, Li, Linxin, Lovelock, Caroline, Chabriat, Hugues, Hennerici, Michael, Wong, Yuen Kwun, Mak, Henry Ka Fung, Prats-Sánchez, Luis, Martínez-Domeño, Alejandro, Inamura, Shigeru, Yoshifuji, Kazuhisa, Arsava, Ethem Murat, Horstmann, Solveig, Purrucker, Jan, Lam, Bonnie Yin Ka, Wong, Adrian, Kim, Young Dae, Song, Tae-Jin, Schrooten, Maarten, Lemmens, Robin, Eppinger, Sebastian, Gattringer, Thomas, Uysal, Ender, Tanriverdi, Zeynep, Bornstein, Natan M, Assayag, Einor Ben, Hallevi, Hen, Tanaka, Jun, Hara, Hideo, Coutts, Shelagh B, Hert, Lisa, Polymeris, Alexandros, Seiffge, David J, Lyrer, Philippe, Algra, Ale, Kappelle, Jaap, Al-Shahi Salman, Rustam, Jäger, Hans R, Lip, Gregory Y H, Mattle, Heinrich P, Panos, Leonidas D, Mas, Jean-Louis, Legrand, Laurence, Karayiannis, Christopher, Phan, Thanh, Gunkel, Sarah, Christ, Nicolas, Abrigo, Jill, Leung, Thomas, Chu, Winnie, Chappell, Francesca, Makin, Stephen, Hayden, Derek, Williams, David J, Kooi, M Eline, van Dam-Nolen, Dianne H K, Barbato, Carmen, Browning, Simone, Wiegertjes, Kim, Tuladhar, Anil M, Maaijwee, Noortje, Guevarra, Christine, Yatawara, Chathuri, Mendyk, Anne-Marie, Delmaire, Christine, Köhler, Sebastian, van Oostenbrugge, Robert, Zhou, Ying, Xu, Chao, Hilal, Saima, Gyanwali, Bibek, Chen, Christopher, Lou, Min, Staals, Julie, Bordet, Régis, Kandiah, Nagaendran, de Leeuw, Frank-Erik, Simister, Robert, van der Lugt, Aad, Kelly, Peter J, Wardlaw, Joanna M, Soo, Yannie, Fluri, Felix, Srikanth, Velandai, Calvet, David, Jung, Simon, Kwa, Vincent I H, Engelter, Stefan T, Peters, Nils, Smith, Eric E, Yakushiji, Yusuke, Orken, Dilek Necioglu, Fazekas, Franz, Thijs, Vincent, Heo, Ji Hoe, Mok, Vincent, Veltkamp, Roland, Ay, Hakan, Imaizumi, Toshio, Gomez-Anson, Beatriz, Lau, Kui Kai, Jouvent, Eric, Rothwell, Peter M, Toyoda, Kazunori, Bae, Hee-Joon, Marti-Fabregas, Joan, and Werring, David J
- Published
- 2019
- Full Text
- View/download PDF
68. Social-Ecological Factors Associated With Higher Levels of Resilience in Children and Youth After Disaster: The Importance of Caregiver and Peer Support
- Author
-
Caroline McDonald-Harker, Julie L. Drolet, Anika Sehgal, Matthew R. G. Brown, Peter H. Silverstone, Pamela Brett-MacLean, and Vincent I. O. Agyapong
- Subjects
disaster ,children ,youth ,mental health ,resilience ,Public aspects of medicine ,RA1-1270 - Abstract
Children and youth are among the most vulnerable to the devastating effects of disaster due to the physical, cognitive, and social factors related to their developmental life stage. Yet children and youth also have the capacity to be resilient and act as powerful catalysts for change in their own lives and wider communities following disaster. Specific factors that contribute to resilience in children and youth, however, remain relatively unexplored. This article examines factors associated with high levels of resilience in 100 children and youth aged 5- to 18-years old who experienced the 2016 Fort McMurray, Alberta wildfire. A mixed-methods design was employed combining quantitative and qualitative data. Quantitative data was obtained from the Children and Youth Resilience Measure (CYRM-28) which measured individual, caregiver, and context factors influencing resilience processes among the participants. Qualitative data was collected through semi-structured interviews to gain further insight into the disaster experiences of children and youth. Quantitative findings reveal higher than average levels of resilience among the participants compared to normative scores. Qualitative findings suggest high levels of resilience were associated with both caregiver factors (specifically physical caregiving), and individual factors (primarily peer support). We discuss how physical caregiving and peer support during and after the wildfire helped mitigate the negative effects of disaster, thus bolstering children and youth's resilience. Implications for understanding the specific social-ecological factors that facilitate and support resiliency processes and overall recovery of children and youth following disaster are also discussed.
- Published
- 2021
- Full Text
- View/download PDF
69. Coherent Tunneling Adiabatic Passage with the Alternating Coupling Scheme
- Author
-
Jong, Lenneke M., Greentree, Andrew D., Conrad, Vincent I., Hollenberg, Lloyd C. L, and Jamieson, David N.
- Subjects
Quantum Physics - Abstract
The use of adiabatic passage techniques to mediate particle transport through real space, rather than phase space is becoming an interesting possibility. We have investigated the properties of Coherent Tunneling Adiabatic Passage (CTAP) with alternating tunneling matrix elements. This geometry, not previously considered in the donor in silicon paradigm, provides an interesting route to long-range quantum transport. We introduce simplified coupling protocols, and transient eigenspectra as well as a realistic gate design for this transport protocol. Using a pairwise treatment of the tunnel couplings for a 5 donor device with 30nm donor spacings, 120nm total chain length, we estimate the time scale required for adiabatic operation to be ~70ns, a time well within measured electron spin and estimated charge relaxation and times for phosphorus donors in silicon., Comment: 13 pages, 5 figures, minor revisions
- Published
- 2009
- Full Text
- View/download PDF
70. Ultra-Early and Short-Term Tranexamic Acid Treatment in Patients With Good- and Poor-Grade Aneurysmal Subarachnoid Hemorrhage.
- Author
-
Tjerkstra, Maud A., Post, René, Germans, Menno R., Vergouwen, Mervyn D. I., Jellema, Korne, Koot, Radboud W., Kruyt, Nyika D., Wolfs, Jasper F. C., De Beer, Frits C., Kieft, Hans H., Nanda, Dharmin, Van Der Pol, Bram, Roks, Gerwin, De Beer, Frank, Reichman, Loes J. A., Brouwers, Paul J. A. M., Kwa, Vincent I. H., Van Der Ree, Taco C., Bienfait, Henri P., and Boogaarts, Hieronymus D.
- Published
- 2024
- Full Text
- View/download PDF
71. Modelling the potential increase in eligible participants in clinical trials with inclusion of community intensive care units patients in Alberta, Canada: a decision tree analysis
- Author
-
Quigley, Nicholas, primary, Binnie, Alexandra, additional, Baig, Nadia, additional, Opgenorth, Dawn, additional, Senaratne, Janek, additional, Sligl, Wendy I., additional, Zuege, Danny J., additional, Rewa, Oleksa, additional, Bagshaw, Sean M., additional, Tsang, Jennifer, additional, and Lau, Vincent I., additional
- Published
- 2023
- Full Text
- View/download PDF
72. A Scoping Review of Adult Inpatient Satisfaction with Mental Health Services
- Author
-
Elgendy, Hossam, primary, Shalaby, Reham, additional, Owusu, Ernest, additional, Nkire, Nnamdi, additional, Agyapong, Vincent I. O., additional, and Wei, Yifeng, additional
- Published
- 2023
- Full Text
- View/download PDF
73. Status after Hospital Discharge: An Observational Study of the Progression of Patients’ Mental Health Symptoms Six Weeks after Hospital Discharge
- Author
-
Mao, Wanying, primary, Shalaby, Reham, additional, Owusu, Ernest, additional, Elgendy, Hossam, additional, Shalaby, Nermin, additional, Agyapong, Belinda, additional, Nichols, Angel, additional, Eboreime, Ejemai, additional, Nkire, Nnamdi, additional, and Agyapong, Vincent I. O., additional
- Published
- 2023
- Full Text
- View/download PDF
74. A study of high NA EUV pattern stitching using rigorous stochastic lithography simulation
- Author
-
Robertson, Stewart A., primary, Schramm, Robert, additional, Vaglio Pret, Alessandro, additional, and Wiaux, Vincent I., additional
- Published
- 2023
- Full Text
- View/download PDF
75. Stitching for high-NA: zooming in on CDU budget
- Author
-
Davydova, Natalia V., primary, van Look, Lieve, additional, Weldeslassie, Ataklti I., additional, Wiaux, Vincent I., additional, Huddleston, Laura, additional, Slachter, Bram, additional, Pellens, Nick I., additional, Timmermans, Frank, additional, Wittebrood, Friso, additional, van Setten, Eelco, additional, and Wilson, Daniel, additional
- Published
- 2023
- Full Text
- View/download PDF
76. Comparison of Resilience, Personal Recovery, and Quality of Life Measures Pre- and Post-Discharge from Inpatient Mental Health Units in Alberta: Analysis of Control Group Data from a Randomized Trial
- Author
-
Owusu, Ernest, primary, Shalaby, Reham, additional, Elgendy, Hossam, additional, Mao, Wanying, additional, Shalaby, Nermin, additional, Agyapong, Belinda, additional, Nichols, Angel, additional, Eboreime, Ejemai, additional, Nkire, Nnamdi, additional, Lawal, Mobolaji A., additional, and Agyapong, Vincent I. O., additional
- Published
- 2023
- Full Text
- View/download PDF
77. The effectiveness of CBT-based daily supportive text messages in improving female mental health during COVID-19 pandemic: results from the Text4Hope program
- Author
-
Dias, Raquel da Luz, primary, Shalaby, Reham, additional, Agyapong, Belinda, additional, Vuong, Wesley, additional, Gusnowski, April, additional, Surood, Shireen, additional, Greenshaw, Andrew James, additional, and Agyapong, Vincent I. O., additional
- Published
- 2023
- Full Text
- View/download PDF
78. The role of microbial pathogens in cancer development: a potential guide to anticancer drugs
- Author
-
Okeleye, Benjamin I., primary, Okudoh, Vincent I., additional, and Ntwampe, Seteno K.O., additional
- Published
- 2020
- Full Text
- View/download PDF
79. Experience from Ghana: Using the Diaspora Resources to Address Local Gaps and Build on Human Resource Capacity
- Author
-
Agyapong, Vincent I. O., primary
- Published
- 2020
- Full Text
- View/download PDF
80. Collective Trauma and Mental Health in Adolescents: A Retrospective Cohort Study of the Effects of Retraumatization
- Author
-
Hannah Pazderka, Matthew R. G. Brown, Vincent I. O. Agyapong, Andrew James Greenshaw, Caroline Beth McDonald-Harker, Shannon Noble, Monica Mankowski, Bonnie Lee, Julie L. Drolet, Joy Omeje, Pamela Brett-MacLean, Deborah Terry Kitching, and Peter H. Silverstone
- Subjects
collective trauma ,retraumatization ,post-traumatic stress disorder ,adolescent ,trauma informed practice ,stress contagion ,Psychiatry ,RC435-571 - Abstract
In the wake of the massive Canadian wildfire of May 2016 in the area of Fort McMurray Alberta, we observed increased rates of mental health problems, particularly post-traumatic stress disorder (PTSD), in school-aged adolescents (ages 11–19). Surprisingly, we did not see these rates decline over the 3.5-year follow-up period. Additionally, our research suggested that the impact of this mass incident resulted in other unanticipated effects, including the finding that children who were not present for and relatively unaffected by the wildfire showed a similar PTSD symptom profile to children more directly involved, suggesting some degree of spillover or stress contagion. A potential explanation for these high rates in individuals who were not present could be undiagnosed retraumatization in some of the students. To investigate this possibility, we compared two groups of students: those who reported the wildfire as their most significant trauma (n = 740) and those who had their most significant trauma prior to the wildfire (n = 295). Those with significant pre-existing trauma had significantly higher rates of both depression and PTSD symptoms, although, unexpectedly the groups exhibited no differences in anxiety level. Taken together, this evidence suggests retraumatization is both longer-lasting and more widespread than might be predicted on a case-by-case basis, suggesting the need to reconceptualize the role of past trauma history in present symptomatology. These findings point to the need to recognize that crises instigated by natural disasters are mass phenomena which expose those involved to numerous unanticipated risks. New trauma-informed treatment approaches are required that incorporate sensitivity to the collective impact of mass crises, and recognize the risk of poorer long-term mental health outcomes for those who experienced trauma in the past.
- Published
- 2021
- Full Text
- View/download PDF
81. The Role of Social Determinants in Mental Health and Resilience After Disasters: Implications for Public Health Policy and Practice
- Author
-
Wanying Mao and Vincent I. O. Agyapong
- Subjects
mental health ,resilience ,disaster ,social determinant ,public health policy ,Public aspects of medicine ,RA1-1270 - Abstract
In this general literature review, we will explore the impacts and contribution of social determinants to mental health and resiliency following both natural and man-made disasters. Natural disasters, such as wildfires, earthquakes, tsunamis, and hurricanes, as well as man-made disasters, such as civil wars, have been known to inflict significant damage to the mental health of the victims. In this paper, we mainly explore some most studied vulnerability and protective social determinant factors such as gender, age, ethnicity, socials support and socioeconomic status for the mental health and resiliency in survivors of such disasters. Several other possible factors such as previous trauma, childhood abuse, family psychiatric history, and subsequent life stress that were explored by some studies were also discussed. We conducted a literature search in major scientific databases, using keywords such as: mental health, social determinants, disasters, wildfires, earthquakes, terrorist attacks, and resilience. We discuss the implications for public health policy and practice.
- Published
- 2021
- Full Text
- View/download PDF
82. Mental Health Symptoms Unexpectedly Increased in Students Aged 11–19 Years During the 3.5 Years After the 2016 Fort McMurray Wildfire: Findings From 9,376 Survey Responses
- Author
-
Matthew R. G. Brown, Hannah Pazderka, Vincent I. O. Agyapong, Andrew J. Greenshaw, Ivor Cribben, Pamela Brett-MacLean, Julie Drolet, Caroline B. McDonald-Harker, Joy Omeje, Bonnie Lee, Monica Mankowsi, Shannon Noble, Deborah T. Kitching, and Peter H. Silverstone
- Subjects
youth ,population mental health ,wildfire natural disaster ,post-traumatic stress disorder (PTSD) ,depression ,anxiety ,Psychiatry ,RC435-571 - Abstract
In Fort McMurray, Alberta, Canada, the wildfire of May 2016 forced the population of 88,000 to rapidly evacuate in a traumatic and chaotic manner. Ten percentage of the homes in the city were destroyed, and many more structures were damaged. Since youth are particularly vulnerable to negative effects of natural disasters, we examined possible long-term psychological impacts. To assess this, we partnered with Fort McMurray Public and Catholic Schools, who surveyed Grade 7–12 students (aged 11–19) in November 2017, 2018, and 2019—i.e., at 1.5, 2.5, and 3.5 years after the wildfire. The survey included validated measurement scales for post-traumatic stress disorder (PTSD), depression, anxiety, drug use, alcohol use, tobacco use, quality of life, self-esteem, and resilience. Data analysis was done on large-scale anonymous surveys including 3,070 samples in 2017; 3,265 samples in 2018; and 3,041 samples in 2019. The results were unexpected and showed that all mental health symptoms increased from 2017 to 2019, with the exception of tobacco use. Consistent with this pattern, self-esteem and quality of life scores decreased. Resilience scores did not change significantly. Thus, mental health measures worsened, in contrast to our initial hypothesis that they would improve over time. Of note, we observed higher levels of mental health distress among older students, in females compared to male students, and in individuals with a minority gender identity, including transgender and gender-non-conforming individuals. These findings demonstrate that deleterious mental health effects can persist in youth for years following a wildfire disaster. This highlights the need for multi-year mental health support programs for youth in post-disaster situations. The indication that multi-year, post-disaster support is warranted is relatively novel, although not unknown. There is a need to systematically investigate factors associated with youth recovery following a wildfire disaster, as well as efficacy of psychosocial strategies during later phases of disaster recovery relative to early post-disaster interventions.
- Published
- 2021
- Full Text
- View/download PDF
83. Text4Support Mobile-Based Programming for Individuals Accessing Addictions and Mental Health Services—Retroactive Program Analysis at Baseline, 12 Weeks, and 6 Months
- Author
-
Jasmine M. Noble, Wesley Vuong, Shireen Surood, Liana Urichuk, Andrew J. Greenshaw, and Vincent I. O. Agyapong
- Subjects
mental health ,intervention ,technology ,text-messaging ,cognitive behavioral therapy ,mobile ,Psychiatry ,RC435-571 - Abstract
Objective: Where traditional approaches fall short, widely accessible and accepted, yet under leveraged, digital technologies such as text messaging present novel opportunities to solve a range of health care solutions. The following provides a preliminary analysis of the Text4Support program, a text-messaging intervention using the principles of cognitive behavioral therapy, which seeks to support the health and well-being of individuals seeking support for addiction or mental health concerns. The goal of this study was to assess whether the Text4Support program improved the perceived overall mental well-being of participants.Methods: The evaluation analyzes survey responses of individuals who were enrolled in the Text4Support program beginning in July 2019, who had completed the 6-months program by May 2020. Participants were asked to provide responses to three surveys during their time in the program—at baseline, 12-weeks and 6-months, which included questions documenting demographic information, general satisfaction with the program, and a participants' level of “global distress” through use of the Clinical Outcomes Routine Evaluation System (CORE-10)—a validated brief 10-item assessment and outcome measurement tool used to assess conditions including anxiety, depression, physical problems, and risk to self.Results and Conclusions: This data set did not include a large enough sample of participants to reach statistical significance. Nevertheless, the study provides some preliminary analysis, and identifies opportunities for the future analysis and research.
- Published
- 2021
- Full Text
- View/download PDF
84. A multiplexed single electron transistor for application in scalable solid-state quantum computing
- Author
-
Conrad, Vincent I., Greentree, Andrew D., and Hollenberg, Lloyd C. L.
- Subjects
Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Single Electron Transistors (SETs) are nanoscale electrometers of unprecedented sensitivity, and as such have been proposed as read-out devices in a number of quantum computer architectures. We show that the functionality of a standard SET can be multiplexed so as to operate as both read-out device and control gate for a solid-state qubit. Multiplexing in this way may be critical in lowering overall gate densities in scalable quantum computer architectures., Comment: 3 pages 3 figures
- Published
- 2006
- Full Text
- View/download PDF
85. Analysis and Geometric Optimization of Single Electron Transistors for Read-Out in Solid-State Quantum Computing
- Author
-
Conrad, Vincent I., Greentree, Andrew D., Jamieson, David N., and Hollenberg, Lloyd C. L.
- Subjects
Condensed Matter - Mesoscale and Nanoscale Physics ,Quantum Physics - Abstract
The single electron transistor (SET) offers unparalled opportunities as a nano-scale electrometer, capable of measuring sub-electron charge variations. SETs have been proposed for read-out schema in solid-state quantum computing where quantum information processing outcomes depend on the location of a single electron on nearby quantum dots. In this paper we investigate various geometries of a SET in order to maximize the device's sensitivity to charge transfer between quantum dots. Through the use of finite element modeling we model the materials and geometries of an Al/Al2O3 SET measuring the state of quantum dots in the Si substrate beneath. The investigation is motivated by the quest to build a scalable quantum computer, though the methodology used is primarily that of circuit theory. As such we provide useful techniques for any electronic device operating at the classical/quantum interface., Comment: 13 pages, 17 figures
- Published
- 2005
- Full Text
- View/download PDF
86. COVID-19 Pandemic: Demographic Predictors of Self-Isolation or Self-Quarantine and Impact of Isolation and Quarantine on Perceived Stress, Anxiety, and Depression
- Author
-
Nnamdi Nkire, Kelly Mrklas, Marianne Hrabok, April Gusnowski, Wesley Vuong, Shireen Surood, Adam Abba-Aji, Liana Urichuk, Bo Cao, Andrew J. Greenshaw, and Vincent I. O. Agyapong
- Subjects
COVID-19 ,pandemic ,stress ,anxiety ,depression ,isolation ,Psychiatry ,RC435-571 - Abstract
Introduction: With the sudden onset and global dispersal of the SARS-CoV-2 virus, many nations including Canada attempted to reduce spread of the resultant COVID-19 syndrome with self-isolation and quarantine, while seeking a cure or vaccine for this disease. Understanding impacts of self-isolation and self-quarantine on stress, anxiety, and depression will help us to mitigate these issues through appropriate development of mental health services.Methods: The sample was drawn from individuals who self-subscribed to Text4Hope, a service that delivers text messages based on a cognitive behavioral therapy framework. Text4Hope was developed to support Albertans during the COVID-19 pandemic. Subscribers were asked for demographic information and if they had to self-isolate or self-quarantine during the pandemic via a survey link. Mental health was assessed using the validated instruments: Perceived Stress Scale (PSS), Generalized Anxiety Disorder-7 item scale (GAD-7), and the Patient Health Questionnaire-9 (PHQ-9). Descriptive statistics and Chi-Square test results were derived using Statistical Package for Social Sciences (SPSS) version-26.Results: 6,041 of 32,805 Text4Hope subscribers (18.4%) completed the survey. Of these respondents, 19.2% had self-isolated or self-quarantined in Alberta as of March 31, 2020 during the COVID-19 pandemic. Post-hoc analysis using adjusted residuals suggested that individuals aged 60 years of age or older, and retirees had a higher likelihood of self-isolation or self-quarantine, compared to respondents with other age or employment characteristics. One-week prevalence rates for self-reported measures of moderate to high stress, likely Generalized Anxiety Disorder (GAD), and likely Major Depressive Disorder (MDD) were 84.9, 46.7, and 41.4%, respectively. Respondents who had to self-isolate or self-quarantine during the COVID-19 pandemic were significantly more likely to present with moderate to high stress, significant anxiety symptomatology, and significant depressive symptomatology.Conclusions: Older age and employment status were significantly associated with the likelihood of self-isolation or self-quarantine. We found elevated self-reported levels of anxiety and depression associated with self-reported COVID-19 pandemic-related self-isolation and self-quarantine activity. These findings have mental health implications both during and after the pandemic and demonstrate the need for greater focus on psychological complications of self-isolation and self-quarantine, and development of optimal ways to manage these pandemic consequences.
- Published
- 2021
- Full Text
- View/download PDF
87. Repetitive Transcranial Magnetic Stimulation for the Treatment of Resistant Depression: A Scoping Review
- Author
-
Medard Kofi Adu, Reham Shalaby, Pierre Chue, and Vincent I. O. Agyapong
- Subjects
treatment-resistant depression ,major depressive disorder ,repetitive transcranial magnetic stimulation ,mental health ,treatment ,Psychology ,BF1-990 - Abstract
Treatment-resistant depression (TRD) is associated with significant disability, and due to its high prevalence, it results in a substantive socio-economic burden at a global level. TRD is the inability to accomplish and/or achieve remission after an adequate trial of antidepressant treatments. Studies comparing repetitive transcranial magnetic stimulation (rTMS) with electroconvulsive therapy (ECT) and pharmacotherapy have revealed evidence of the therapeutic efficacy of rTMS in TRD. These findings suggest a crucial role for rTMS in the management of TRD. This article aims to conduct a comprehensive scoping review of the current literature concerning the use of rTMS and its therapeutic efficacy as a treatment modality for TRD. PubMed, PsycINFO, Medline, Embase, and Cinahl were used to identify important articles on rTMS for TRD. The search strategy was limited to English articles within the last five years of data publication. Articles were included if they reported on a completed randomized controlled trial (RCT) of rTMS intervention for TRD. The exclusion criteria involved studies with rTMS for the treatment of conditions other than TRD, and study and experimental protocols of rTMS on TRD. In total, 17 studies were eligible for inclusion in this review. The search strategy spanned studies published in the last five years, to the date of the data search (14 February 2022). The regional breakdown of the extracted studies was North American (n = 9), European (n = 5), Asian (n = 2) and Australian (n = 1). The applied frequencies of rTMS ranged from 5 Hz to 50 Hz, with stimulation intensities ranging from 80% MT to 120% MT. Overall, 16 out of the 17 studies suggested that rTMS treatment was effective, safe and tolerated in TRD. For patients with TRD, rTMS appears to provide significant benefits through the reduction of depressive symptoms, and while there is progressive evidence in support of the same, more research is needed in order to define standardized protocols of rTMS application in terms of localization, frequency, intensity, and pulse parameters.
- Published
- 2022
- Full Text
- View/download PDF
88. Evaluating the Impact of an Innovative Public Speaking Competition to Promote Psychiatry as a Career Option for Ghanaian Medical Students
- Author
-
Agyapong, Vincent I. O., Hrabok, Marianne, Agyapong-Opoku, Gerald, Khinda, Harsimran, Owusu-Antwi, Ruth, Osei, Akwasi, Ohene, Sammy, Ulzen, Thaddeus, and Gilligan, Paul
- Published
- 2019
- Full Text
- View/download PDF
89. Prevalence Rates and Correlates of Probable Major Depressive Disorder in Residents of Fort McMurray 6 Months After a Wildfire
- Author
-
Agyapong, Vincent I. O., Juhás, Michal, Brown, Matthew R. G., Omege, Joy, Denga, Edward, Nwaka, Bernard, Akinjise, Idowu, Corbett, Sandra E., Hrabok, Marianne, Li, Xin-Min, Greenshaw, Andrew, and Chue, Pierre
- Published
- 2019
- Full Text
- View/download PDF
90. Stimulating achievements: The mediating effect of employee commitment between high-performance work practices and employee engagement
- Author
-
Damaro Olusoji Arubayi and Vincent I. O. Odiri
- Subjects
Strategy and Management ,Earth and Planetary Sciences (miscellaneous) ,Decision Sciences (miscellaneous) ,Management Science and Operations Research - Abstract
Drawing on the social exchange paradigm, this study evaluated the mediating effects of employee commitment (EC) in the relationship between high-performance work practices (HPWP) and employee engagement (EE) in Nigeria. The study used the social exchange theory and this paradigm has been previously used in the works of Blau (1964), Gouldner (1960), and Settoon et al. (1996). The study adopts a cross-sectional survey research design via questionnaire administration. Three employee engagement (vigor, dedication and absorption) and employee commitment (affective, normative and continuance) dimensions, and six high-performance work practices (employee selection process, motivational compensation, job and work design, participative decision-making, information sharing, and training/development) were employed. Data collected from one hundred and sixty-eight employees in selected ministries in Delta State were analyzed via structural equation modeling (SEM). Results showed that engagement positively affects high-performance work practices. The result also indicated that employee commitment mediated the influence of high-performance work practices on employee engagement. The results further suggest that affective commitment does not mediate the link between vigor and high-performance work practices. Notably, the theoretical and managerial inferences have been methodically discussed in this paper.
- Published
- 2023
- Full Text
- View/download PDF
91. Peer Support in Mental Health: Literature Review
- Author
-
Shalaby, Reham A Hameed and Agyapong, Vincent I O
- Subjects
Psychology ,BF1-990 - Abstract
BackgroundA growing gap has emerged between people with mental illness and health care professionals, which in recent years has been successfully closed through the adoption of peer support services (PSSs). Peer support in mental health has been variously defined in the literature and is simply known as the help and support that people with lived experience of mental illness or a learning disability can give to one another. Although PSSs date back to several centuries, it is only in the last few decades that these services have formally evolved, grown, and become an integral part of the health care system. Debates around peer support in mental health have been raised frequently in the literature. Although many authors have emphasized the utmost importance of incorporating peer support into the health care system to instill hope; to improve engagement, quality of life, self-confidence, and integrity; and to reduce the burden on the health care system, other studies suggest that there are neutral effects from integrating PSSs into health care systems, with a probable waste of resources. ObjectiveIn this general review, we aimed to examine the literature, exploring the evolution, growth, types, function, generating tools, evaluation, challenges, and the effect of PSSs in the field of mental health and addiction. In addition, we aimed to describe PSSs in different, nonexhaustive contexts, as shown in the literature, that aims to draw attention to the proposed values of PSSs in such fields. MethodsThe review was conducted through a general search of the literature on MEDLINE, Google Scholar, EMBASE, Scopus, Chemical Abstracts, and PsycINFO. Search terms included peer support, peer support in mental health, social support, peer, family support, and integrated care. ResultsThere is abundant literature defining and describing PSSs in different contexts as well as tracking their origins. Two main transformational concepts have been described, namely, intentional peer support and transformation from patients to peer support providers. The effects of PSSs are extensive and integrated into different fields, such as forensic PSSs, addiction, and mental health, and in different age groups and mental health condition severity. Satisfaction of and challenges to PSS integration have been clearly dependent on a number of factors and consequently impact the future prospect of this workforce. ConclusionsThere is an internationally growing trend to adopt PSSs within addiction and mental health services, and despite the ongoing challenges, large sections of the current literature support the inclusion of peer support workers in the mental health care workforce. The feasibility and maintenance of a robust PSS in health care would only be possible through collaborative efforts and ongoing support and engagement from all health care practitioners, managers, and other stakeholders.
- Published
- 2020
- Full Text
- View/download PDF
92. Long-Term Mental Health Effects of a Devastating Wildfire Are Amplified by Socio-Demographic and Clinical Antecedents in Elementary and High School Staff
- Author
-
Vincent I. O. Agyapong, Amanda Ritchie, Matthew R. G. Brown, Shannon Noble, Monica Mankowsi, Edward Denga, Bernard Nwaka, Idowu Akinjise, Sandra E. Corbett, Shahram Moosavi, Pierre Chue, Xin-Min Li, Peter H. Silverstone, and Andrew J. Greenshaw
- Subjects
wildfires ,depression ,anxiety ,Post-Traumatic Stress Disorder ,drugs ,alcohol ,Psychiatry ,RC435-571 - Abstract
ObjectivesTo assess the likely prevalence rates of Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD) and Post-Traumatic Stress Disorder (PTSD) in staff of Fort McMurray School Districts eighteen months after a May 2016 wildfire, and to determine possible predictors.MethodsA quantitative cross-sectional survey was used to collect data through self-administered online questionnaires to determine likely MDD, GAD and PTSD using well validated self-report questionnaires.ResultsOf 1,446 staff who were sent the online survey link in an e-mail, 197 completed the survey, of which there were 168 females (85%) and 29 males (15%). The one-month prevalence rates for likely MDD, GAD and PTSD among the school staff were 18.3, 15.7 and 10.2% respectively. There were statistically significant associations between multiple socio-demographic and clinical variables likely MDD, GAD and PTSD among respondents.ConclusionKnowledge of key factors for MDD, GAD and PTSD may be helpful for policy makers when formulating population level social and clinical programs, to mitigate the mental health effects of future natural disasters.
- Published
- 2020
- Full Text
- View/download PDF
93. Reducing Burnout and Promoting Health and Wellness Among Medical Students, Residents, and Physicians in Alberta: Protocol for a Cross-Sectional Questionnaire Study
- Author
-
Kim, Esther, Mallett, Robert, Hrabok, Marianne, Yang, Yajing Alicia, Moreau, Chantal, Nwachukwu, Izu, Kravtsenyuk, Maryana, Abba-Aji, Adam, Li, Daniel, and Agyapong, Vincent I O
- Subjects
Medicine ,Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
BackgroundBurnout is an increasingly common and insidious phenomenon experienced by workers in many different fields, although it is of particular concern among physicians and trainees due to the nature of their work. It is estimated that one-third of practicing physicians will experience burnout during their career, and this rate is expected to continue to increase. Burnout has significant implications, as it has been identified as a contributor to increased medical errors, decreased patient satisfaction, substance use, workforce attrition, and suicide. ObjectiveThis study will evaluate the prevalence and impact of burnout on physicians, residents, and medical students in Alberta. MethodsQuantitative and qualitative data collected through self-administered, anonymous, online questionnaires will be used in this cross-sectional provincial study design. Data collection tools were developed based on published literature and questions from previously validated instruments. The tools capture relevant demographic information, mental health status, and rates of burnout, as well as factors contributing to both burnout and resilience among respondents. We anticipate a sample size of 777 medical students, 959 residents, and 1961 physicians to represent the respective ratios of trainees and practicing physicians in the province of Alberta. ResultsStudy recruitment will begin in September 2020, with 4 weeks of data collection. The results of this study are anticipated within 12 months from the end of data collection. It is expected that the results will provide an overview of the prevalence of burnout among those training and working in medicine in Alberta, identify contributors to burnout, and help develop interventions aimed at reducing burnout. ConclusionsThis study’s aim is to examine burnout prevalence and contributing factors among medical trainees and physicians in Alberta. It is expected that the results will identify and examine individual and organizational practices that contribute to burnout and help develop strategies and interventions focused on mitigating burnout and its sequelae. International Registered Report Identifier (IRRID)PRR1-10.2196/16285
- Published
- 2020
- Full Text
- View/download PDF
94. Five Years after the Fort McMurray Wildfire: Prevalence and Correlates of Low Resilience
- Author
-
Medard Kofi Adu, Ejemai Eboreime, Reham Shalaby, Adegboyega Sapara, Belinda Agyapong, Gloria Obuobi-Donkor, Wanying Mao, Ernest Owusu, Folajinmi Oluwasina, Hannah Pazderka, and Vincent I. O. Agyapong
- Subjects
disaster ,wildfires ,predictors ,mental health ,PTSD ,resilience ,Psychology ,BF1-990 - Abstract
Background: The Fort McMurray wildfire of 3 May 2016 was one of the most devastating natural disasters in Canadian history. Although resilience plays a crucial role in the daily functioning of individuals by acting as a protective shield that lessens the impact of disasters on their mental well-being, to date little is known about the long-term impact of wildfires on resilience and associated predictors of low resilience. Objectives: The objective of the study was to assess the prevalence and predictors of resilience among residents of Fort McMurray five years after the wildfires. Method: This was a quantitative cross-sectional study. A self-administered online survey which included standardized rating scales for resilience (BRS), anxiety (GAD-7), depression (PHQ-9), and post-traumatic stress disorder (PTSD)(PCL-C) was used to determine the prevalence of resilience as well as its demographic, clinical, and wildfire-related predictors. The data were collected between 24 April and 2 June 2021 and analyzed using the Statistical Package for Social Sciences (SPSS) version 25 using univariate analysis with a chi-squared test and binary logistic regression analysis. Results: A total of 186 residents completed the survey out of 249 who accessed the online survey, producing a response rate of 74.7%. Most of the respondents were females (85.5%, 159), above 40 years of age (81.6%, 80), employed (94.1%, 175), and in a relationship (71%, 132). Two variables—having had PTSD symptoms (OR = 2.85; 95% CI: 1.06–7.63), and age—were significant predictors of low resilience in our study. The prevalence of low resilience in our sample was 37.4%. Conclusions: Our results suggest that age and the presence of PTSD symptoms were the independent significant risk factors associated with low resilience five years after the Fort McMurray wildfire disaster. Further research is needed to enhance understanding of the pathways to resilience post-disaster to identify the robust predictors and provide appropriate interventions to the most vulnerable individuals and communities.
- Published
- 2022
- Full Text
- View/download PDF
95. One Year after the Flood: Prevalence and Correlates of Post-Traumatic Stress Disorder among Residents in Fort McMurray
- Author
-
Wanying Mao, Ejemai Eboreime, Reham Shalaby, Nnamdi Nkire, Belinda Agyapong, Hannah Pazderka, Gloria Obuobi-Donkor, Medard Adu, Ernest Owusu, Folajinmi Oluwasina, Yanbo Zhang, and Vincent I. O. Agyapong
- Subjects
PTSD ,trauma ,flood ,natural disaster ,mental health ,support ,Psychology ,BF1-990 - Abstract
Background: The 2020 Fort McMurray (FMM) and area flood caused more than $228 million in insured damage, affected over 1200 structures, and more than 13,000 people were evacuated. Objective: This study sought to determine the prevalence of post-traumatic stress disorder (PTSD)-like symptoms and the risk predictors among the population of FMM one year after the 2020 flooding. Methods: An online quantitative cross-sectional survey was distributed to residents of FMM via REDCap between 24 April to 2 June 2021 to collect sociodemographic, clinical, and flood-related information. The PTSD checklist for DSM-5 (PCL-C) was used to assess likely PTSD among respondents. Results: 186 of 249 respondents completed all essential self-assessment questionnaires in the analysis, yielding a response rate of 74.7%. The prevalence of likely PTSD was 39.6% (65). Respondents with a history of depression were more likely to develop PTSD symptoms (OR = 5.71; 95% CI: 1.68–19.36). Similarly, responders with limited and no family support after the disaster were more prone to report PTSD symptoms ((OR = 2.87; 95% CI: 1.02–8.05) and (OR = 2.87; 95% CI: 1.06–7.74), respectively). Conclusions: Our research indicated that history of depression and the need for mental health counseling significantly increased the risk of developing PTSD symptoms following flooding; family support is protective. Further studies are needed to explore the relations between the need to receive counseling and presenting with likely PTSD symptoms.
- Published
- 2022
- Full Text
- View/download PDF
96. COVID-19 Pandemic in a Vulnerable Population: Prevalence and Correlates of Anxiety
- Author
-
Reham Shalaby, Ejemai Eboreime, Nnamdi Nkire, Belinda Agyapong, Hannah Pazderka, Gloria Obuobi-Donkor, Medard Kofi Adu, Wanying Mao, Ernest Owusu, Folajinmi Oluwasina, and Vincent I. O. Agyapong
- Subjects
anxiety ,trauma ,COVID-19 ,cross-sectional ,online survey ,Fort McMurray ,Psychology ,BF1-990 - Abstract
Background: The COVID-19 pandemic has produced negative mental health outcomes. These effects were more prominent in vulnerable communities that experienced prior similar disasters. The study aimed to examine the likelihood and correlates of anxiety symptoms among Fort McMurray (FMM) residents, during the COVID-19 pandemic. Methods: A cross-sectional online survey questionnaire was applied between 24 April and 2 June 2021, at FMM, to gather sociodemographic, COVID-19, and clinical information, including generalized anxiety disorder (using GAD-7 scale). Results: Overall, 186 individuals completed the survey (response rate 74.7%). Most of the respondents were females (159, 85.5%); above 40 years (98, 52.7%); employed (175, 94.1%); and in relationship (132, 71%). The prevalence of moderate-to-severe anxiety was (42.5%, 71) on GAD-7 self-reported scale. Subscribers who reported that they would like to receive mental health support; have received no family support since COVID-19 declaration; and have lost their job during the pandemic were all more likely to report moderate-to-severe anxiety (OR = 3.39; 95% CI: 1.29–8.88), (OR = 4.85; 95% CI: 1.56–15.03), and (OR = 4.40; 95% CI: 1.01–19.24), respectively. Conclusions: Anxiety levels were high among FMM residents, compared to levels before COVID-19. Clinical and social factors significantly predicted likely anxiety in the Fort McMurray population, during the COVID-19 pandemic. It is imperative that resources are mobilized to support vulnerable communities during the COVID-19 pandemic.
- Published
- 2022
- Full Text
- View/download PDF
97. Patient and Family Experience With Discharge Directly Home From the Pediatric ICU
- Author
-
Roumeliotis, Nadia, primary, Desforges, Jade, additional, French, Mary-Ellen, additional, Dupre-Roussel, Joannie, additional, Fiest, Kirsten M., additional, Lau, Vincent I., additional, Lacroix, Jacques, additional, and Carnevale, Franco A., additional
- Published
- 2023
- Full Text
- View/download PDF
98. Integrating image-based LLMs on edge-devices for underwater robotics
- Author
-
Kehtarnavaz, Nasser, Shirvaikar, Mukul V., Sundaravadivel, Prabha, Roselyn, Preetha J., Narayanaswamy, Vedachalam, Jeyaraj, Vincent I., Ramesh, Aishree, and Khanal, Aaditya
- Published
- 2024
- Full Text
- View/download PDF
99. Safety Outcomes of Direct Discharge Home From ICUs: An Updated Systematic Review and Meta-Analysis (Direct From ICU Sent Home Study)*
- Author
-
Vincent I, Lau, Ryan, Donnelly, Sehar, Parvez, Jivanjot, Gill, Sean M, Bagshaw, Ian M, Ball, John, Basmaji, Deborah J, Cook, Kirsten M, Fiest, Robert A, Fowler, Jonathan F, Mailman, Claudio M, Martin, Bram, Rochwerg, Damon C, Scales, Henry T, Stelfox, Alla, Iansavichene, and Eric J, Sy
- Subjects
Intensive Care Units ,Humans ,Critical Care and Intensive Care Medicine ,Patient Discharge - Abstract
To evaluate the impact of direct discharge home (DDH) from ICUs compared with ward transfer on safety outcomes of readmissions, emergency department (ED) visits, and mortality.We searched MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and Cumulative Index to Nursing and Allied Health Literature from inception until March 28, 2022.Randomized and nonrandomized studies of DDH patients compared with ward transfer were eligible.We screened and extracted studies independently and in duplicate. We assessed risk of bias using the Newcastle-Ottawa Scale for observational studies. A random-effects meta-analysis model and heterogeneity assessment was performed using pooled data (inverse variance) for propensity-matched and unadjusted cohorts. We assessed the overall certainty of evidence for each outcome using the Grading Recommendations Assessment, Development and Evaluation approach.Of 10,228 citations identified, we included six studies. Of these, three high-quality studies, which enrolled 49,376 patients in propensity-matched cohorts, could be pooled using meta-analysis. For DDH from ICU, compared with ward transfers, there was no difference in the risk of ED visits at 30-day (22.4% vs 22.7%; relative risk [RR], 0.99; 95% CI, 0.95-1.02; p = 0.39; low certainty); hospital readmissions at 30-day (9.8% vs 9.6%; RR, 1.02; 95% CI, 0.91-1.15; p = 0.71; very low-to-low certainty); or 90-day mortality (2.8% vs 2.6%; RR, 1.06; 95% CI, 0.95-1.18; p = 0.29; very low-to-low certainty). There were no important differences in the unmatched cohorts or across subgroup analyses.Very low-to-low certainty evidence from observational studies suggests that DDH from ICU may have no difference in safety outcomes compared with ward transfer of selected ICU patients. In the future, this research question could be further examined by randomized control trials to provide higher certainty data.
- Published
- 2022
- Full Text
- View/download PDF
100. Prehospital transdermal glyceryl trinitrate in patients with presumed acute stroke (MR ASAP)
- Author
-
Sophie A van den Berg, Simone M Uniken Venema, Hendrik Reinink, Jeannette Hofmeijer, Wouter J Schonewille, Irene Miedema, Puck S S Fransen, D Martijn O Pruissen, Theodora W M Raaijmakers, Gert W van Dijk, Frank-Erik de Leeuw, Jorine A van Vliet, Vincent I H Kwa, Henk Kerkhoff, Alex van 't Net, Rene Boomars, Arjen Siegers, Tycho Lok, Klaartje Caminada, Laura M Esteve Cuevas, Marieke C Visser, Casper P Zwetsloot, Jooske M F Boomsma, Mirjam H Schipper, Roeland P J van Eijkelenburg, Olvert A Berkhemer, Daan Nieboer, Hester F Lingsma, Bart J Emmer, Robert J van Oostenbrugge, Aad van der Lugt, Yvo B W E M Roos, Charles B L M Majoie, Diederik W J Dippel, Paul J Nederkoorn, H Bart van der Worp, Ayla van Ahee, Frank Visseren, Patricia Halkes, Ruben van Eijk, Michelle Simons, Wilma Pellikaan, Wilma Van Wijngaarden, Eva Ponjee, Petra Geijtenbeek, Ton Arts, Elles Zock, Wilma Oudshoorn, Frans Steenwinkel, Hamdia Samim, Mark van Zandwijk, Lisette Vrielink, Peter Jan Mulder, Aico Gerritsen, Jim Ijzermans, Marjan Kooijman, Oscar Francissen, Rick van Nuland, Wim van Zwam, Linda Jacobi, Rene van den Berg, Ludo Beenen, Adriaan van Es, Pieter-Jan van Doormaal, Geert Lycklama a Nijeholt, Ido van den Wijngaard, Albert Yoo, Lonneke Yo, Jasper Martens, Bas Hammer, Stefan Roosendaal, Anton Meijer, Menno Krietemeijer, Reinoud Bokkers, Anouk van der Hoorn, Dick Gerrits, Jonathan Coutinho, Ben Jansen, Sanne Manschot, Peter Koudstaal, Koos Keizer, Vicky Chalos, Adriaan Versteeg, Lennard Wolff, Henk van Voorst, Matthijs van der Sluijs, Arnolt-Jan Hoving, Kilian Treurniet, Natalie LeCouffe, Rob van de Graaf, Robert-Jan Goldhoorn, Wouter Hinseveld, Anne Pirson, Lotte Sondag, Manon Kappelhof, Manon Tolhuisen, Josje Brouwer, Wouter van der Steen, Leon Rinkel, Agnetha Bruggeman, Rita Sprengers, Martin Sterrenberg, Sabrina Verheesen, Leontien Heiligers, Yvonne Martens, Naziha El Ghannouti, Miranda Slotboom, MUMC+: MA Neurologie (3), MUMC+: Hersen en Zenuw Centrum (3), Klinische Neurowetenschappen, RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, RS: Carim - B05 Cerebral small vessel disease, Graduate School, ACS - Atherosclerosis & ischemic syndromes, ANS - Neurovascular Disorders, Neurology, Radiology and Nuclear Medicine, ANS - Cellular & Molecular Mechanisms, ACS - Microcirculation, ACS - Pulmonary hypertension & thrombosis, Biomedical Engineering and Physics, ANS - Brain Imaging, ANS - Compulsivity, Impulsivity & Attention, Radiology & Nuclear Medicine, Public Health, Radiology and nuclear medicine, Pediatrics, Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE), Damage and Repair in Cancer Development and Cancer Treatment (DARE), TechMed Centre, and Clinical Neurophysiology
- Subjects
Adult ,Adolescent ,Ischemic Attack ,Transient ,Nitroglycerin/therapeutic use ,Ambulances ,Brain Ischemia/drug therapy ,Disorders of movement Donders Center for Medical Neuroscience [Radboudumc 3] ,Brain Ischemia ,Stroke ,Nitroglycerin ,Treatment Outcome ,Ischemic Attack, Transient ,2023 OA procedure ,Humans ,Neurology (clinical) ,Stroke/drug therapy ,Cerebral Hemorrhage/drug therapy ,Cerebral Hemorrhage ,Ischemic Stroke - Abstract
Contains fulltext : 287508.pdf (Publisher’s version ) (Closed access) BACKGROUND: Pooled analyses of previous randomised studies have suggested that very early treatment with glyceryl trinitrate (also known as nitroglycerin) improves functional outcome in patients with acute ischaemic stroke or intracerebral haemorrhage, but this finding was not confirmed in a more recent trial (RIGHT-2). We aimed to assess whether patients with presumed acute stroke benefit from glyceryl tr initrate started within 3 h after symptom onset. METHODS: MR ASAP was a phase 3, randomised, open-label, blinded endpoint trial done at six ambulance services serving 18 hospitals in the Netherlands. Eligible participants (aged ≥18 years) had a probable diagnosis of acute stroke (as assessed by a paramedic), a face-arm-speech-time test score of 2 or 3, systolic blood pressure of at least 140 mm Hg, and could start treatment within 3 h of symptom onset. Participants were randomly assigned (1:1) by ambulance personnel, using a secure web-based electronic application with random block sizes stratified by ambulance service, to receive either transdermal glyceryl trinitrate 5 mg/day for 24 h plus standard care (glyceryl trinitrate group) or to standard care alone (control group) in the prehospital setting. Informed consent was deferred until after arrival at the hospital. The primary outcome was functional outcome assessed with the modified Rankin Scale (mRS) at 90 days. Safety outcomes included death within 7 days, death within 90 days, and serious adverse events. Analyses were based on modified intention to treat, and treatment effects were expressed as odds ratios (ORs) or common ORs, with adjustment for baseline prognostic factors. We separately analysed the total population and the target population (ie, patients with intracerebral haemorrhage, ischaemic stroke, or transient ischaemic attack). The target sample size was 1400 patients. The trial is registered as ISRCTN99503308. FINDINGS: On June 24, 2021, the MR ASAP trial was prematurely terminated on the advice of the data and safety monitoring board, with recruitment stopped because of safety concerns in patients with intracerebral haemorrhage. Between April 4, 2018, and Feb 12, 2021, 380 patients were randomly allocated to a study group. 325 provided informed consent or died before consent could be obtained, of whom 170 were assigned to the glyceryl trinitrate group and 155 to the control group. These patients were included in the total population. 201 patients (62%) had ischaemic stroke, 34 (10%) transient ischaemic attack, 56 (17%) intracerebral haemorrhage, and 34 (10%) a stroke-mimicking condition. In the total population (n=325), the median mRS score at 90 days was 2 (IQR 1-4) in both the glyceryl trinitrate and control groups (adjusted common OR 0·97 [95% CI 0·65-1·47]). In the target population (n=291), the 90-day mRS score was 2 (2-4) in the glyceryl trinitrate group and 3 (1-4) in the control group (0·92 [0·59-1·43]). In the total population, there were no differences between the two study groups with respect to death within 90 days (adjusted OR 1·07 [0·53-2·14]) or serious adverse events (unadjusted OR 1·23 [0·76-1·99]). In patients with intracerebral haemorrhage, 12 (34%) of 35 patients allocated to glyceryl trinitrate versus two (10%) of 21 allocated to the control group died within 7 days (adjusted OR 5·91 [0·78-44·81]); death within 90 days occurred in 16 (46%) of 35 in the glyceryl trinitrate group and 11 (55%) of 20 in the control group (adjusted OR 0·87 [0·18-4·17]). INTERPRETATION: We found no sign of benefit of transdermal glyceryl trinitrate started within 3 h of symptom onset in the prehospital setting in patients with presumed acute stroke. The signal of potential early harm of glyceryl trinitrate in patients with intracerebral haemorrhage suggests that glyceryl trinitrate should be avoided in this setting. FUNDING: The Collaboration for New Treatments of Acute Stroke consortium, the Brain Foundation Netherlands, the Ministry of Economic Affairs, Stryker, Medtronic, Cerenovus, and the Dutch Heart Foundation.
- Published
- 2022
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.