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Abstract Background In the face of costly fixation hardware with varying performance for treatment of distal humeral fractures, a novel technique (U-Frame) is proposed using conventional implants in a 180° plate arrangement. In this in-vitro study the biomechanical stability of this method was compared with the established technique which utilizes angular stable locking compression plates (LCP) in a 90° configuration. Methods An unstable distal 3-part fracture (AO 13-C2.3) was created in eight pairs of human cadaveric humeri. All bone pairs were operated with either the "Frame" technique, where two parallel plates are distally interconnected, or with the LCP technique. The specimens were cyclically loaded in simulated flexion and extension of the arm until failure of the construct occurred. Motion of all fragments was tracked by means of optical motion capturing. Construct stiffness and cycles to failure were identified for all specimens. Results Compared to the LCP constructs, the "Frame" technique revealed significant higher construct stiffness in extension of the arm (P = 0.01). The stiffness in flexion was not significantly different (P = 0.16). Number of cycles to failure was found significantly larger for the "Frame" technique (P = 0.01). Conclusions In an in-vitro context the proposed method offers enhanced biomechanical stability and at the same time significantly reduces implant costs.

Abstract Background Angle-stable locking plates have improved the surgical management of fractures. However, locking implants are costly and removal can be difficult. The aim of this in vitro study was to evaluate the biomechanical performance of a newly proposed crossed-screw concept ("Fence") utilizing conventional (non-locked) implants in comparison to conventional LC-DCP (limited contact dynamic compression plate) and LCP (locking compression plate) stabilization, in a human cadaveric diaphyseal gap model. Methods In eight pairs of human cadaveric femora, one femur per pair was randomly assigned to receive a Fence construct with either elevated or non-elevated plate, while the contralateral femur received either an LCP or LC-DCP instrumentation. Fracture gap motion and fatigue performance under cyclic loading was evaluated successively in axial compression and in torsion. Results were statistically compared in a pairwise setting. Results The elevated Fence constructs allowed significantly higher gap motion compared to the LCP instrumentations (axial compression: p ≤ 0.011, torsion p ≤ 0.015) but revealed similar performance under cyclic loading (p = 0.43). The Fence instrumentation with established bone-plate contact revealed larger fracture gap motion under axial compression compared to the conventional LC-DCP osteosynthesis (p ≤ 0.017). However, all contact Fence specimens survived the cyclic test, whereas all LC-DCP constructs failed early during torsion testing (p < 0.001). All failures occurred due to breakage of the screw heads. Conclusions Even though accentuated fracture gap motion became obvious, the "Fence" technique is considered an alternative to cost-intensive locking-head devices. The concept can be of interest in cases were angle-stable implants are unavailable and can lead to new strategies in implant design.

BACKGROUND: Tibiotalocalcaneal arthrodesis with a retrograde nail is an established procedure. Many patients considered for this arthrodesis have poor bone stock, which may make it difficult to obtain construct stability. This study was undertaken to determine whether stability could be enhanced by the cement augmentation of the calcaneal locking screws. METHODS: A cannulated and perforated screw, and a technique for cement augmentation via this screw, were developed. Eight pairs of human cadaver bones were instrumented with a retrograde intramedullary device (Expert Hindfoot Arthrodesis Nail, Synthes AG, Solothurn, Switzerland). Within each pair, one specimen was randomized to have the nail interlocked in the calcaneus with two conventional screws; while the other specimen was similarly instrumented with the use of two cement-augmented screws. The bone mineral density was determined. In quasi-static tests, the neutral zone and the range of motion of the constructs were determined. Subsequently the specimens were tested in dorsiflexion/plantar flexion until failure occurred. The neutral zone and the range of motion of the constructs were determined every 200 cycles. FINDINGS: Augmentation resulted in significantly greater stiffness and a significantly smaller range of motion in the quasi-static dorsiflexion/plantar flexion test, and in a significantly smaller neutral zone in all quasi-static tests. With cyclic loading, the number of cycles to failure was significantly larger in the augmented group. In both groups, bone mineral density was significantly correlated with the number of cycles to failure. Two augmented screws broke. INTERPRETATION: Cement augmentation confers significant mechanical benefit in hindfoot arthrodesis and therefore can be used as a salvage procedure. Further development should be performed to validate the concept. [ABSTRACT FROM AUTHOR]

For complex distal femoral fractures, a single lateral locking compression plate or retrograde intramedullary nail may not achieve a stable environment for fracture healing. Various types of double fixation constructs have been featured in the current literature. Double-plate construct and nail-and-plate construct are two common double fixation constructs for distal femoral fractures. Double fixation constructs have been featured in studies on comminuted distal femoral fractures, distal femoral fracture with medial bone defects, periprosthetic fractures, and distal femoral non-union. A number of case series reported a generally high union rate and satisfactory functional outcomes for double fixation of distal femoral fractures. In this review, we present the state of the art of double fixation constructs for distal femoral fractures with a focus on double-plate and plate-and-nail constructs.

Making motorcycle rides safer by advanced technology is an ongoing challenge in the context of developing driving assistant systems and safety infrastructure. Determining which section of a road and which driving behaviour is "safe" or "unsafe" is rarely possible due to the individual differences in driving experience, driving style, fitness and potentially available assistant systems. This study investigates the feasibility of a new approach to quantify motorcycle riding risk for an experimental sample of bikers by collecting motorcycle-specific dynamic data of several riders on selected road sections. Comparing clustered dynamics with the observed dynamic data at known risk spots, we provide a method to represent individual risk estimates in a single risk map for the investigated road section. This yields a map of potential risk spots, based on an aggregation of individual risk estimates. The risk map is optimized to include most of the previous accident sites, while keeping the overall area classified as risky small. As such, with data collected on a large scale, the presented methodology could guide safety inspections at the highlighted areas of a risk map and be the basis of further studies into the safety relevant differences in driving styles., (Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Motivated by proposed thermometry measurement on an open quantum system, we present a simple model of an externally driven qubit interacting with a finite-sized fermion environment acting as a calorimeter. The derived dynamics is governed by a stochastic Schrödinger equation coupled to the temperature change of the calorimeter. We prove a fluctuation relation and deduce from it a notion of entropy production. Finally, we discuss the first and second law associated with the dynamics.

Purpose: The novel dynamic locking screw (DLS) was developed to improve bone healing with locked-plate osteosynthesis by equalising construct stiffness at both cortices. Due to a theoretical damping effect, this modulated stiffness could be beneficial for fracture fixation in osteoporotic bone. Therefore, the mechanical behaviour of the DLS at the screw-bone interface was investigated in an artificial osteoporotic bone model and compared with conventional locking screws (LHS)., Methods: Osteoporotic surrogate bones were plated with either a DLS or a LHS construct consisting of two screws and cyclically axially loaded (8,500 cycles, amplitude 420 N, increase 2 mN/cycle). Construct stiffness, relative movement, axial screw migration, proximal (P) and distal (D) screw pullout force and loosening at the bone interface were determined and statistically evaluated., Results: DLS constructs exhibited a higher screw pullout force of P 85 N [standard deviation (SD) 21] and D 93 N (SD 12) compared with LHS (P 62 N, SD 28, p = 0.1; D 57 N, SD 25, p < 0.01) and a significantly lower axial migration over cycles compared with LHS (p = 0.01). DLS constructs showed significantly lower axial construct stiffness (403 N/mm, SD 21, p < 0.01) and a significantly higher relative movement (1.1 mm, SD 0.05, p < 0.01) compared with LHS (529 N/mm, SD 27; 0.8 mm, SD 0.04)., Conclusion: Based on the model data, the DLS principle might also improve in vivo plate fixation in osteoporotic bone, providing enhanced residual holding strength and reducing screw cutout. The influence of pin-sleeve abutment still needs to be investigated.

Information processing machines at the nanoscales are unavoidably affected by thermal fluctuations. Efficient design requires understanding how nanomachines can operate at minimal energy dissipation. Here we focus on mechanical systems controlled by smoothly varying potential forces. We show that optimal control equations come about in a natural way if the energy cost to manipulate the potential is taken into account. When such a cost becomes negligible, an optimal control strategy can be constructed by transparent geometrical methods which recover the solution of optimal mass transport equations in the overdamped limit. Our equations are equivalent to hierarchies of kinetic equations of a form well known in the theory of dilute gases. From our results, optimal strategies for energy efficient nanosystems may be devised by established techniques from kinetic theory.

Introduction: To improve proximal plate fixation of periprosthetic femur fractures, a prototype locking plate with proximal posterior angulated screw positioning was developed and biomechanically tested., Methods: Twelve fresh frozen, bone mineral density matched human femora, instrumented with cemented hip endoprosthesis were osteotomized simulating a Vancouver B1 fracture. Specimens were fixed proximally with monocortical (LCP) or angulated bicortical (A-LCP) head-locking screws. Biomechanical testing comprised quasi-static axial bending and torsion and cyclic axial loading until catastrophic failure with motion tracking., Results: Axial bending and torsional stiffness of the A-LCP construct were (1,633 N/mm ± 548 standard deviation (SD); 0.75 Nm/deg ± 0.23 SD) at the beginning and (1,368 N/mm ± 650 SD; 0.67 Nm/deg ± 0.25 SD) after 10,000 cycles compared to the LCP construct (1,402 N/mm ± 272 SD; 0.54 Nm/deg ± 0.19 SD) at the beginning and (1,029 N/mm ± 387 SD; 0.45 Nm/deg ± 0.15) after 10,000 cycles. Relative movements for medial bending and axial translation differed significantly between the constructs after 5,000 cycles (A-LCP 2.09° ± 0.57 SD; LCP 5.02° ± 4.04 SD; p = 0.02; A-LCP 1.25 mm ± 0.33 SD; LCP 2.81 mm ± 2.32 SD; p = 0.02) and after 15,000 cycles (A-LCP 2.96° ± 0.70; LCP 6.52° ± 2.31; p = 0.01; A-LCP 1.68 mm ± 0.32; LCP 3.14 mm ± 0.68; p = 0.01). Cycles to failure (criterion 2 mm axial translation) differed significantly between A-LCP (15,500 ± 2,828 SD) and LCP construct (5,417 ± 7,236 SD), p = 0.03., Conclusion: Bicortical angulated screw positioning showed less interfragmentary osteotomy movement and improves osteosynthesis in periprosthetic fractures.

The transfixation pin cast (TPC) is an external skeletal fixation technique used to treat horses with distal limb fractures, but its use is often associated with pin-loosening and an increased risk of treatment failure. To address implant loosening, the pin sleeve cast system (PSC) was recently designed and consists of a pin-sleeve unit inserted into the bone. Each pin runs through a sleeve placed in the bone, making contact at two fixed points only within the sleeve. Each pin is attached to a ring embedded in a resin cast. In this report, the mechanical performance of a traditional TPC pin arrangement was compared with that of the PSC using validated finite element models of bone substitutes previously tested in vitro. The PSC resulted in a marked reduction in peak strain magnitude around the pins and a more even distribution of strain across the bone cortex. The two systems resulted in comparable proximal fragment displacement and had a similar stress concentration around bone defects during implant removal. The findings suggest that the PSC load transfer mechanism is effective even in geometrically complex structures like equine bones., (Copyright © 2010 Elsevier Ltd. All rights reserved.)

Study Design: Retrospective clinical study in patients with dorso-ventral thoraco-lumbar spondylodesis., Objective: To investigate whether the ratio between graft cross sectional area and the surface area of the adjacent endplates has any effect on the midterm stability of the spondylodesis. Dorso-ventral spondylodesis in the region of the thoraco-lumbar spine is one of the most frequent operations in orthopaedic surgery. Anterior stabilization with autologous iliac crest graft currently is a standard approach in many hospitals. Although numerous recommendations are given how to perform this technique, no clinical advice is available with regard to minimum graft size., Methods: Sixty-four-slice CT-scans were obtained from 82 patients 4-12 months after posterior spondylodesis with anterior implantation of iliac crest graft and stabilization with an internal fixator. The scans were analyzed using image analysis software. First, the cross sectional area of the graft was calculated and then the surface area of the adjacent endplates. The ratio between graft cross sectional area and endplate surface area was then calculated from these two values. The grafts were then evaluated in sagittal reconstruction for signs of fracture., Results: The probability for graft fracture in autologous tricortical grafts was >0.1% (p < 0.001) if the graft cross sectional area exceeded 23.9% of the surface area of the adjacent endplates. Patients with lower ratio values had a higher fracture risk and below a value of 10% all grafts fractured., Conclusion: The relationship between graft cross sectional area and adjacent endplate area has an important effect on graft midterm stability in ventral spondylodesis of the thoraco-lumbar spine. In our opinion, the risk of graft fractures in dorso-ventral spondylodesis can be reduced by implantation of an appropriately sized graft without any additional procedures or instrumentation.

Aim: Bone quality is a main factor in implant fixation. After having shown promising results, we have further investigated the use of the DensiProbe™ as an intraoperative measurement tool for evaluation of calcaneal bone quality and prediction of nailed hindfoot arthrodesis failure., Method: In this add-on study 19 nail arthrodeses were performed using a conventional screw plus a locked blade (n = 6) or plus a locked screw (n = 13) in the calcaneus. A specially devised tool was inserted at the fixation sites of the screws and the cancellous break-away torque was measured. The constructs were then cyclically loaded to failure., Results: We saw a wide range of BMD (1.9-185.9 mgHA/cm³, mean 102.4 mg/cm³, SD 53.5). The peak torque was 0.47-1.78 Nm (mean 0.92 Nm, SD 0.46) at the proximal screw site (PSS) and 0.24 and 1.2 Nm (mean 0.63 Nm, SD 0.37) at the distal screw site (DSS), respectively, and 0.42 and 1.52 Nm (mean 1.00 Nm, SD 0.36) in the screw plus blade group (PSS). The number of cycles correlated with peak torque (two screws group PSS: p = 0.002, r² = DSS: 0.61 p = 0.001, r² = 0.90; screw plus blade group PSS: p = 0.001, r² = 0.99). Peak torque also correlated with BMD in both groups (two screws group PSS: p = 0.01, r² = 0.71; DSS: p = 0.001; r² = 0.83; screw plus blade group PSS: 0.42 and 1.52 Nm, mean 1.00 Nm, SD 0.36)., Conclusion: A mechanical bone measurement tool like the DensiProbe™ seems to be suitable for predicting tibiotalocalcaneal arthrodesis failure in a biomechanical test set-up. As a restriction in clinical practice failure is multifactorial and prediction cannot be based upon these measurements only., (© Georg Thieme Verlag KG Stuttgart · New York.)

Background: Unstable distal tibia fractures are challenging injuries that require surgery. Increasingly, intramedullary nails are being used. However, fracture site anatomy may cause distal-fragment stabilization and fixation problems and lead to malunion/nonunion. We studied the influence of angle-stable nail locking on fracture gap movement and other biomechanical parameters., Methods: Eight pairs of fresh human cadaver tibiae were used. The bone mineral density (BMD) was determined. All tibiae were nailed with a Synthes Expert tibial nail. Within each pair, one tibia was randomized to receive conventional locking screws; the other, angle-stable screws with sleeves. A 7-mm osteotomy was created 10 mm above the upper distal locking screw, to simulate an AO 42-A3 fracture. Biomechanical testing involved nondestructive mediolateral and anteroposterior pure bending, followed by cyclic combined axial and torsional loading to catastrophic failure. The neutral zone was determined. Fracture gap movement was monitored with 3-D motion tracking., Results: The angle-stable locked constructs had a significantly smaller mediolateral neutral zone (mean: 0.04 degree; p=0.039) and significantly smaller fracture gap angulation (p=0.043). The number of cycles to failure did not differ significantly between the locking configurations. BMD was a significant covariate affecting the number of cycles to failure (p=0.008). However, over the first 20,000 cycles, there was no significant correlation in the angle-stable construct., Conclusions: Angle-stable locking of the Expert tibial nail was associated with a significant reduction in the mediolateral neutral zone and in fracture gap movement. Angle-stable fixation also reduced the influence of BMD over the first 20,000 cycles.

Introduction: The gold standard for treating transverse olecranon fractures is tension band fixation. A problem with this technique is migration of the K-wires leading to premature hardware removal. The aim of this study is to compare stability provided by two new techniques designed to eliminate the problem with backing out of K-wires, with that of the recommended tension band technique, performed with a biomechanical in vitro investigation. Our hypothesis was that the two new techniques would provide at least equal stability as the traditional tension band fixation., Methods: Transverse olecranon osteotomies were created in human cadaveric elbows to simulate a type 21-B1.1 fracture. Three groups of 8 specimens were instrumented with: (1) recommended AO tension band technique; (2) modified K-wires with eyelets and tension band; (3) staples across the fracture with tension band. Each elbow was tested in a 90° flexed position. The triceps tendon was sinusoidally loaded by applying two load steps at 500 and 700 N for 4000 cycles each. Relative movements between the fragments were determined., Results: At the end of the first and second load step the displacement of the osteotomy at the posterior ulnar side was significantly less for the staples across the fracture with tension band as compared to both other groups. There were no significant differences between groups 1 and 2., Conclusion: Since clinical results depend partly on stable fixation, it is concluded that using staples in the clinical situation might provide better results than the currently recommended tension band technique.

Background: The optimal surgical treatment for displaced proximal humeral fractures is still controversial. A new implant for the treatment of three-part fractures has been recently designed. It supplements the existing Expert Humeral Nail with a locking plate. We developed a novel humeral cadaveric model and the existing implant and the prototype were biomechanically compared to determine their ability in maintaining interfragmentary stability., Methods: The bone mineral density of eight pairs of cadaveric humeri was assessed and a three-part proximal humeral fracture was simulated with a Greater Tuberosity osteotomy and a surgical neck wedge ostectomy. The specimens were randomly assigned to either treatment. A bone anchor simulated part of a rotator cuff tendon pulling on the Greater Tuberosity. Specimens were initially tested in axial compression and afterward with a compound cyclic load to failure. An optical 3D motion tracking system continuously monitored the relative interfragmentary movements., Findings: The specimen stabilized with the prototype demonstrated higher stiffness (P=0.036) and better interfragmentary stability (P values<0.028) than the contralateral treated with the existing implant. There was no correlation between the bone mineral density and any of the investigated variables., Interpretation: The convenience of this new IM-nail and locking plate assembly must be confirmed in vivo but the current study provides a biomechanical rationale for its use in the treatment of three-part proximal humeral fractures. The improved stability could be advantageous in particular when medial buttress is missing, even in osteoporotic bone., (Copyright © 2010 Elsevier Ltd. All rights reserved.)

Background: Tendon transfers and calcaneal osteotomies are commonly used to treat symptoms related to medial ankle arthrosis in fixed pes cavovarus. However, the relative effect of these osteotomies in terms of lateralizing the ground contact point of the hindfoot and redistributing ankle joint contact stresses are unknown., Materials and Methods: Pes cavovarus with fixed hindfoot varus was simulated in eight cadaver specimens. The effect of three types of calcaneal osteotomies on the migration of the center of force and tibiotalar peak pressure at 300 N axial static load (half-body weight) were recorded using pressure sensors., Results: A significant lateral shift of the center of force was observed: 4.9 mm for the laterally closing Z-shaped osteotomy with additional lateralization of the tuberosity, 3.4 mm for the lateral sliding osteotomy of the calcaneal tuberosity, and 2.7 mm for the laterally closing Z-shaped osteotomy (all p < 0.001). A significant peak pressure reduction was recorded: -0.53 MPa for the Z-shaped osteotomy with lateralization, -0.58 MPa for the lateral sliding osteotomy of the calcaneal tuberosity, and -0.41 MPa for the Z-shaped osteotomy (all p < 0.01)., Conclusion: This cadaver study supports the hypothesis that lateralizing calcaneal osteotomies substantially help to normalize ankle contact stresses in pes cavovarus.

Background: In the face of costly fixation hardware with varying performance for treatment of distal humeral fractures, a novel technique (U-Frame) is proposed using conventional implants in a 180 degrees plate arrangement. In this in-vitro study the biomechanical stability of this method was compared with the established technique which utilizes angular stable locking compression plates (LCP) in a 90 degrees configuration., Methods: An unstable distal 3-part fracture (AO 13-C2.3) was created in eight pairs of human cadaveric humeri. All bone pairs were operated with either the "Frame" technique, where two parallel plates are distally interconnected, or with the LCP technique. The specimens were cyclically loaded in simulated flexion and extension of the arm until failure of the construct occurred. Motion of all fragments was tracked by means of optical motion capturing. Construct stiffness and cycles to failure were identified for all specimens., Results: Compared to the LCP constructs, the "Frame" technique revealed significant higher construct stiffness in extension of the arm (P = 0.01). The stiffness in flexion was not significantly different (P = 0.16). Number of cycles to failure was found significantly larger for the "Frame" technique (P = 0.01)., Conclusions: In an in-vitro context the proposed method offers enhanced biomechanical stability and at the same time significantly reduces implant costs.

Objective: To evaluate the efficacy of a novel pin-sleeve cast (PSC) system for external fixation of distal limb fractures in horses and to compare it with the transfixation pin cast (TPC) system., Study Design: Experimental., Sample Population: One bone substitute each was used for the TPC and PSC systems. The PSC was tested in 4 configurations characterized by different pin preloads., Methods: Specimens were loaded in axial compression in the elastic range. Variables compared statistically were: bone substitute axial displacement and axial strain measured above implants with strain gauges. Pin preload was correlated with the variables investigated. Load to failure and a fatigue tests supplemented the investigation., Results: The PSC configuration with the highest pin preload showed a significantly lower axial displacement compared with the TPC. No significant differences were observed between all other PSC configurations and the TPC. All PSC systems had a significant decrease in recorded strain compared with the TPC system. Pin axial preload inversely correlated with axial displacement but had no effect on axial strain. In the failure test, the PSC encountered plastic deformation earlier than the TPC. In the fatigue test, the PSC ran >200,000 cycles., Conclusions: Preliminary in vitro tests showed that the PSC system significantly reduced peri-implant strain while concurrently having comparable axial displacement to the TPC system., Clinical Relevance: The PSC system has the potential to reduce the risk of pin loosening in horses.

Background: Angle-stable locking plates have improved the surgical management of fractures. However, locking implants are costly and removal can be difficult. The aim of this in vitro study was to evaluate the biomechanical performance of a newly proposed crossed-screw concept ("Fence") utilizing conventional (non-locked) implants in comparison to conventional LC-DCP (limited contact dynamic compression plate) and LCP (locking compression plate) stabilization, in a human cadaveric diaphyseal gap model., Methods: In eight pairs of human cadaveric femora, one femur per pair was randomly assigned to receive a Fence construct with either elevated or non-elevated plate, while the contralateral femur received either an LCP or LC-DCP instrumentation. Fracture gap motion and fatigue performance under cyclic loading was evaluated successively in axial compression and in torsion. Results were statistically compared in a pairwise setting., Results: The elevated Fence constructs allowed significantly higher gap motion compared to the LCP instrumentations (axial compression: p

Background: Lapidus (first metatarsocuneiform joint) arthrodesis is an established procedure for the management of hallux valgus. This study investigated the utility of fixation with a medial locking plate with adjunct compression screw versus fixation with two crossed screws., Materials and Methods: Eight pairs of fresh-frozen human specimens were used in a matched pair test. Bone mineral density (BMD) was measured with peripheral quantitative computed tomography (pQCT). Fixation with two 4-mm-diameter crossed screws was compared versus a medial locking plate (X-Locking Plate 2.4/2.7; Synthes, Solothurn, Switzerland) with adjunct 4-mm-diameter compression screw. The specimens were tested in a four-point bending test. Parameters obtained were initial stiffness; plantar joint-line gapping after one cycle, 100 and 1000 cycles; and number of cycles to failure. Failure was defined as more than or equal to 3 mm plantar gapping., Results: The groups did not differ significantly with regard to BMD (p = 0.866) and initial stiffness (p = 0.889). The plate-and-screw construct showed significantly less movement during testing, and significantly (p = 0.001) more cycles to failure than did the crossed-screw construct. There was a significant correlation (crossed-screw construct: p = 0.014; plate-and-screw construct: p = 0.010) between BMD and the number of cycles to failure., Conclusion: Under cyclic loading conditions, the construct using a medial locking plate with adjunct compression screw was superior to the construct using two crossed screws., Clinical Relevance: The medial locking-plate technique described could help shorten the period of nonweightbearing and reduce the risk of non-union.

Background: Bone strength is currently measured with indirect techniques. We investigated the use of an intraoperative mechanical measurement for local bone strength determination and prediction of intramedullary-nail fusion failure. We investigated whether intraoperative local bone strength determination may be useful to the surgeon in predicting intramedullary nail hindfoot fusion performance., Materials and Methods: In seven human specimens, bone mineral density (BMD) was determined with qCT. A device (DensiProbe) specially devised for nailed tibiotalocalcaneal arthrodesis (TTCA) was inserted at the intended calcaneal screw sites of an intramedullary nail, and the cancellous break-away torque was measured. The constructs were then cyclically loaded to failure in dorsiflexion-plantarfexion., Results: The BMD range was wide (42.8 to 185.9 mg HA/cm(3)). The proximal-screw site peak torque was 0.47 to 1.61 Nm; distal-screw site peak torque was 0.24 to 1.06 Nm. The number of cycles to failure correlated with peak torque both proximally (p = 0.021; r(2) = 0.69) and distally (p = 0.001; r(2) = 0.92). Proximally, peak torque did not correlate with BMD (p = 0.060; r(2) = 0.54); distally, it correlated significantly (p = 0.003; r(2) = 0.86)., Conclusion: DensiProbe measurements can be used in the hindfoot to assess bone strength. In this study, specimens that failed early could be identified. However, in clinical practice fusion failure is multifactorial in origin, and failure prediction cannot be based upon peak torque measurements alone., Clinical Relevance: The technique described here may be of use to give an intraoperative decision aid to predict intramedullary nail hindfoot fusion performance.

Background: The tension band wiring technique is the most common method of transverse patella fracture fixation. Since post-operative instabilities have been reported for this technique, alternative osteosynthesis solutions are of interest. We investigated the biomechanical behaviour of a new staple technique for treatment of transverse patella fractures in a cadaveric model., Methods: Eight human cadaveric knees with femur and tibia including soft tissue were used. A transverse osteotomy of the patella was created. Each specimen was fixed consecutively with tension band wiring and two Nitinol compression staples. Testing was performed by pull on the quadriceps tendon between a 90 degrees flexed position and full knee extension for up to 5,000 cycles., Findings: At 1,000 cycles, fracture site displacements in flexion and extension were significantly smaller for the staple group at the ventral aspect of the patella as compared to the tension band wiring group. With a failure criterion of 2mm fracture site displacement, cycles until failure were significantly smaller for the staple group., Interpretation: This study provides evidence based on a cadaveric model that compression staples have a promising potential to treat transverse patella fractures.

Background: Retrograde intramedullary nailing is an established technique for tibiotalocalcaneal arthrodesis (TTCA). In poor bone stock (osteoporosis, neuroarthropathy), device fixation in the hindfoot remains a problem. Fixed-angle spiral-blade fixation of the nail in the calcaneus could be useful., Materials and Methods: In seven matched pairs of human below-knee specimens, bone mineral density (BMD) was determined, and TTCA was performed with an intramedullary nail (Synthes Hindfoot Arthrodesis Nail HAN Expert Nailing System), using a conventional screw plus a fixed-angle spiral blade versus a conventional screw plus a fixed-angle screw, in the calcaneus. The constructs were subjected to quasi-static loading (dorsiflexion/plantarflexion, varus/valgus, rotation) and to cyclic loading to failure. Parameters studied were construct neutral zone (NZ) and range of motion (ROM), and number of cycles to failure., Results: With dorsiflexion/plantarflexion loading, the screw-plus-spiral-blade constructs had a significantly smaller ROM in the quasi-static test (p = 0.028) and early in the cyclic test (p = 0.02); differences in the other parameters were not significant. There was a significant correlation between BMD and cycles to failure for the two-screw constructs (r = 0.94; p = 0.002) and for the screw-plus-spiral-blade constructs (r = 0.86; p = 0.014)., Conclusion: In TTCA with a HAN Expert Nailing System, the use of a calcaneal spiral blade can further reduce motion within the construct. This may be especially useful in poor bone stock., Clinical Relevance: Results obtained in this study could be used to guide the operating surgeon's TTCA strategy.

Assessment of trabecular microarchitecture may improve estimation of biomechanical strength, but visualization of trabecular bone structure in vivo is challenging. We tested the feasibility of assessing trabecular microarchitecture in the spine using multidetector CT (MDCT) on intact human cadavers in an experimental in vivo-like setup. BMD, bone structure (e.g., bone volume/total volume = BV/TV; trabecular thickness = Tb.Th; structure model index = SMI) and bone texture parameters were evaluated in 45 lumbar vertebral bodies using MDCT (mean in-plane pixel size, 274 microm(2); slice thickness, 500 microm). These measures were correlated with structure measures assessed with microCT at an isotropic spatial resolution of 16 microm and to microfinite element models (microFE) of apparent modulus and stiffness. MDCT-derived BMD and structure measures showed significant correlations to the density and structure obtained by microCT (BMD, R(2) = 0.86, p < 0.0001; BV/TV, R(2) = 0.64, p < 0.0001; Tb.Th, R(2) = 0.36, p < 0.01). When comparing microCT-derived measures with microFE models, the following correlations (p < 0.001) were found for apparent modulus and stiffness, respectively: BMD (R(2) = 0.58 and 0.66), BV/TV (R(2) = 0.44 and 0.58), and SMI (R(2) = 0.44 and 0.49). However, the overall highest correlation (p < 0.001) with microFE app. modulus (R(2) = 0.75) and stiffness (R(2) = 0.76) was achieved by the combination of QCT-derived BMD with the bone texture measure Minkowski Dimension. In summary, although still limited by its spatial resolution, trabecular bone structure assessment using MDCT is overall feasible. However, when comparing with microFE-derived bone properties, BMD is superior compared with single parameters for microarchitecture, and correlations further improve when combining with texture measures.

Introduction: Intramedullary nailing is the treatment of choice for most displaced tibial shaft fractures. The ability to maintain a mechanically stable fixation becomes more difficult the further the fracture extends distally or proximally or when unreamed tibial nails are used. We assumed that a new angular stable locking option would provide improved stability and reduced interfragmentary movements in a distal tibia in vitro fracture model., Materials and Methods: Left and right bones of 8 pairs of human cadaveric tibiae were randomly assigned to either a group with conventional locked or a group with angular stable locked intramedullary nails. Nails of 10-mm-diameter were used after reaming up to 11 mm. A transverse distal osteotomy was performed and the specimens were tested mechanically under eccentric axial load. A video optical measurement system was used to determine the angular displacement of the osteotomy gap during loading., Results: Construct stiffness, maximum load of the bone-nail construct and gap angle at 0.5 kN load were measured. The group with the angular stable locking option showed significantly higher stiffness values and reduced fracture gap motion compared to the group with conventional locked nails., Discussion: A new angular stable locking option of intramedullary nails provides higher stability in terms of construct stiffness and reduced interfragmentary movements in a distal tibia in vitro fracture model.

The prediction of bone strength can be improved when determining bone mineral density (BMD) in combination with measures of trabecular microarchitecture. The goal of this study was to assess parameters of trabecular bone structure and texture of the calcaneus by clinical multi-detector row computed tomography (MDCT) in an experimental in situ setup and to correlate these parameters with microCT (microCT) and biomechanical testing. Thirty calcanei in 15 intact cadavers were scanned using three different protocols on a 64-slice MDCT scanner with an in-plane pixel size of 208 microm and 500 microm slice thickness. Bone cores were harvested from each specimen and microCT images with a voxel size of 16 microm were obtained. After image coregistration, trabecular bone structure and texture were evaluated in identical regions on the MDCT images. After data acquisition, uniaxial compression testing was performed. Significant correlations between MDCT- and microCT-derived measures of bone volume fraction (BV/TV), trabecular thickness (Tb.Th) and trabecular separation (Tb.Sp) were found (range, R(2)=0.19-0.65, p<0.01 or 0.05). The MDCT-derived parameters of volumetric BMD, app. BV/TV, app. Tb.Th and app. Tb.Sp were capable of predicting 60%, 63%, 53% and 25% of the variation in bone strength (p<0.01). When combining those measures with one additional texture index (either GLCM, TOGLCM or MF.euler), prediction of mechanical competence was significantly improved to 86%, 85%, 71% and 63% (p<0.01). In conclusion, this study showed the feasibility of trabecular microarchitecture assessment using MDCT in an experimental setup simulating the clinical situation. Multivariate models of BMD or structural parameters combined with texture indices improved prediction of bone strength significantly and might provide more reliable estimates of fracture risk in patients.

Background: Compaction of cancellous bone is believed to prevent cut-out. This in vitro study quantified the compaction in the femoral head due to insertion of a dynamic hip screw-blade with and without predrilling and investigated the resulting implant anchorage under cyclic loading., Methods: Eight pairs of human cadaveric femoral heads were instrumented with a dynamic hip screw-blade made of Polyetheretherketon. Pairwise instrumentation was performed either with or without predrilling the specimens. CT scanning was performed before and after implantation, to measure bone-compaction. Subsequently the implant was removed and a third scan was performed to analyze the relaxation of the bone structure. Commercial implants were reinserted and the specimens were cyclically loaded until onset of cut-out occurred. The bone-implant interface was monitored by means of fluoroscopic imaging throughout the experiment. Paired t-tests were performed to identify differences regarding compaction, relaxation and cycles to failure., Findings: Bone density in the surrounding of the implant increased about 30% for the non-predrilled and 20% for the predrilled group when inserting the implant. After implant removal the predrilled specimens fully relaxed; the non-predrilled group showed about 10% plastic deformation. No differences were found regarding cycles to failure (P=0.32)., Interpretation: Significant bone-compaction due to blade insertion was verified. Even though compaction was lower when predrilling the specimens, mainly elastic deformation was present, which is believed to primarily enhance the implant anchorage. Cyclic loading tests confirmed this thesis. The importance of the implantation technique with regard to predrilling is therefore decreased.

Background: The Dynamic Hip Screw is well established for the treatment of femoral neck fractures. However, cut-out occurs in 1-6% of all cases. This study compared the biomechanical performance of a helical shaped implant (DHS-Blade) to the Dynamic Hip Screw in an unstable femoral neck fracture model., Methods: Ten pairs of human cadaveric femora were either instrumented with a DHS-Blade or a Dynamic Hip Screw. Osteotomies were created using a custom-made saw-guide. Cyclic loading was performed by introducing in vivo measured load-trajectories to the femoral head. Starting at 1500 N, the load was stepwise increased until failure of the construct. Radiographs were taken in 5000 cycles increments to identify onset of femoral head migration with respect to the implant. A survival analysis was performed on the cycles to onset of migration. A paired t-test was carried out on the displacements of the femoral head relative to the shaft as determined by optical motion tracking., Findings: One hundred percent migrations occurred for the Dynamic Hip Screw compared to 50% for the DHS-Blade. The survival probability in terms of implant anchorage was found higher for the blade (P=0.023). However, significant higher deformation of the repair construct was observed for the DHS-Blade (P=0.004)., Interpretation: The study showed superior implant anchorage of the DHS-Blade compared to the DHS, which might reduce the cut-out risk. Nevertheless, the blade allowed higher deformation of the femur mainly resulting in shortening of the neck, which might be due to a systematic loss of fracture reduction.

Increased fracture risk has been reported for the adjacent vertebral bodies after vertebroplasty. This increase has been partly attributed to the high Young's modulus of commonly used polymethylmethacrylate (PMMA). Therefore, a compliant bone cement of PMMA with a bulk modulus closer to the apparent modulus of cancellous bone has been produced. This compliant bone cement was achieved by introducing pores in the cement. Due to the reduced failure strength of that porous PMMA cement, cancellous bone augmented with such cement could deteriorate under dynamic loading. The aim of the present study was to assess the potential of acute failure, particle generation and mechanical properties of cancellous bone augmented with this compliant cement in comparison to regular cement. For this purpose, vertebral biopsies were augmented with porous- and regular PMMA bone cement, submitted to dynamic tests and compression to failure. Changes in Young's modulus and height due to dynamic loading were determined. Afterwards, yield strength and Young's modulus were determined by compressive tests to failure and compared to the individual composite materials. No failure occurred and no particle generation could be observed during dynamical testing for both groups. Height loss was significantly higher for the porous cement composite (0.53+/-0.21%) in comparison to the biopsies augmented with regular cement (0.16+/-0.1%). Young's modulus of biopsies augmented with porous PMMA was comparable to cancellous bone or porous cement alone (200-700 MPa). The yield strength of those biopsies (21.1+/-4.1 MPa) was around two times higher than for porous cement alone (11.6+/-3.3 MPa).

Difficulty in removing implants used in trauma patients can be a complication, and increased bone-implant adhesion likely is a major contributing factor. In vitro studies have shown that surface morphology of implant materials has the ability to influence cellular responses, with polished surfaces decreasing the potential for mineralization. This study examined the effect of polishing commercially pure titanium (cpTi) and the titanium alloy TAN on the removal torque and percentage bone-implant contact in cortical and cancellous bone of sheep. Polishing had a significant effect on both removal torque and percentage bone-implant contact, with the polished implants demonstrating a lower removal torque in both cortical and cancellous bone. Polished cpTi and stainless steel were similar in terms of surface roughness and removal torque. However, polished TAN, which was not as smooth as polished cpTi, did not show the same low level for reducing removal torque. Improved polishing of TAN should reduce the removal torque further. The results of the study show that polishing is promising in improving the ease of implant removal after fracture fixation and repair., ((c) 2008 Orthopaedic Research Society.)

Objective: To compare tibial plateau rotation after tibial plateau leveling osteotomy with the radiographically planned rotation and to determine the effect of translations and rotations of the tibial plateau fragment on the biomechanical stability of the construct under cyclic loading., Study Design: Experimental biomechanical study., Animals: Cadaveric canine pelvic limbs (n=10)., Methods: Titanium pins were inserted into the tibial plateau and the proximal metaphysis to track the fragment movements by means of computed tomography (CT) imaging. CT scans were performed (1) before osteotomy, (2) after osteotomy and tibial plateau rotation, and (3) after stabilization with plate and screws. The bones were then cyclically loaded in axial compression., Results: The radiographically planned tibial plateau rotation correlated significantly with the achieved rotation (r=0.73, P=.016), although deviations of up to 4.7 degrees were observed. A significant positive correlation between the amount of rotation about the sawing axis and the plastic deformation of the construct after 30,000 test cycles could be found (r=0.81, P=.005)., Conclusion: Considerable deviation occurred between planned and achieved rotation of the tibial plateau fragment. Lower degrees of rotation were beneficial for biomechanical stability., Clinical Relevance: Dogs with larger tibial plateau angles may be at a relatively higher risk for fixation failure, but further studies are needed to establish a safe margin of tibial plateau rotation.

Objective: To compare locking screws with conventional screws inserted in the tibial plateau fragment for reduction and stability of the construct after tibial plateau leveling osteotomy (TPLO), using a locking TPLO plate., Study Design: Experimental biomechanical study., Animals: Cadaveric canine pelvic limbs (n=8 pairs)., Methods: TPLO was stabilized with either conventional cortical screws or locking screws in a compressed osteotomy model. Titanium pins inserted into the tibial plateau and proximal metaphysis were used to track bone fragment location by computed tomography (CT) imaging. CT imaging was performed after osteotomy reduction, after plate stabilization, and after 30,000 cycles of axial compression testing. After 30,000 cycles, cyclic loading was continued with monotonically increasing peak-load until failure., Results: The magnitude of rotation about the sawing axis was significantly greater for the conventional screw group because of plate application (P=.009). Translational movement of the tibial plateau fragment toward the plate was significantly greater for the conventional screw group (P=.006). There were no significant differences between groups in stiffness or number of cycles to failure., Conclusion: Maintenance of tibial plateau position was significantly superior for the locking screw group during plate application; however, screw type had no effect on fixation stability under cyclic loading., Clinical Relevance: These results suggest that conventional screws and careful contouring of the TPLO plate can provide comparable mechanical stability to fixation with locking screws in the tibial plateau under load-sharing conditions, but potentially at the expense of osteotomy reduction.

Objectives: To investigate the bone-implant-anchorage of 90-degree double-plate osteosynthesis in simulated complete intra-articular distal humerus fractures using conventional reconstruction plates (CRP), locking compression plates (LCP), and distal humerus plates (DHP), depending on the bone mineral density (BMD) of the cadaver specimens., Methods: Groups (CRP, LCP, DHP, n=8; LCP, DHP, n=13) in distal humerus cadaver bones were created based on BMD. The fracture model was an unstable intraarticular distal humerus fracture with a transverse osteotomy gap representing metaphyseal comminution (AO type 13-C2.3). Flexion and extension stiffness as well as cycles until failure due to screw pullout under cyclic loading were evaluated. Estimates of BMD values, below which failure was likely to occur, were determined., Results: Stiffness values were not significantly different between groups (extension: P=0.881, flexion: P=0.547). Under cyclic loading, consistent screw pullout failure occurred at BMD values below about 400 mg/cm for CRP and below about 300 mg/cm for LCP constructs. Comparing BMD-matched groups of 8 and 13 specimens respectively, the failure rate was significantly lower for the DHP (0/8) than for the CRP (5/8; P=0.026) and tended to be lower for the DHP (0/13) as compared to the LCP (4/13; P=0.096)., Conclusion: Bone-implant anchorage was different between locking and nonlocking plate constructs and depended on BMD. While in good bone quality implant choice was not critical, both locking plates provided superior resistance against screw loosening as compared to the CRP at low BMD values (<420 mg/cm). Based on our laboratory results, we conclude that locking plates such as the LCP and DHP are constructs designed to keep anatomical reduction in the presence of comminution and poor bone quality in a low intra-articular fracture of the distal humerus.

Objective: To compare the stiffness and strength of AO bone plates (DCP, LC-DCP, VCP, RCP, and LP) and the Clamp-Rod Internal Fixation System (CRIF)., Study Design: In vitro., Sample Size: 12 individual implants of 18 plate dimensions and four sizes of CRIF, each corresponding to 2.0, 2.4/2.7, 3.5, or 4.5 mm screw sizes., Methods: Implant-constructs of each plate and CRIF were created using Canevasit rods as a bone substitute in an unstable gap fracture model. Six implant-constructs of each type were tested under single cycle four-point bending loading, and six were tested under single cycle torsional loading until permanent plastic deformation occurred., Results: Torsional stiffness and yield load of the DCP were always significantly greater than the CRIF within the same group. Bending properties of the 2.0 DCP were not significantly different to the 2.0 CRIF. The 2.7 DCP had significantly higher bending values than the 2.7 CRIF. The bending stiffness of the 3.5 DCP and 4.5 DCP was significantly less than their CRIF counterparts. While the bending yield load of the 3.5 DCP was significantly greater than the 3.5 CRIF, the bending yield load of the 4.5 DCP was significantly less than the 4.5 CRIF., Conclusion: A weakness was found in the torsional resistance of the CRIF constructs compared to the DCP constructs., Clinical Significance: Bone holding power and applied screw torque should be considered when using the CRIF system in clinical application.

Background: Comminuted calcaneal fractures are a consequence of high impact trauma to the foot. Stable fixation and anatomically correct repositioning of the joint surfaces are often a problem. To improve fracture treatment, surgical techniques in combination with new augmentation materials have been tested., Methods: This study presents a new concept of osteosynthesis of complex calcaneal fractures in combination with an alternative augmentation technique. Solid body augmentation was developed and mechanically tested against standard techniques. The solid body was used for augmentation of a central fracture void in combination with conventional plating., Results: The results show a statistically significant higher stability of the new hybrid osteosynthesis concept against conventional plating techniques under in-vitro conditions., Conclusions: This work investigated a new concept of internal support of multifragmentary calcaneal fractures. Augmentation of defect voids in the calcaneus with a mechanically stable solid body implant in combination with stable screw anchorage in this implant leads to a higher stability compared to plate-fixation and augmentation with cancellous bone under in-vitro conditions.

Study Design: A biomechanical study was designed to assess implant cut-out of three different angular stable anterior spinal implants. Subsidence of the implant relative to the vertebral body was measured during an in vitro cyclic loading test., Objectives: The objective of the study was to evaluate two prototypes (Synthes) of a new anterior spine fixator with different screw angulations in comparison to the established MACSTL(R) Twin Screw Concept (Aesculap). The influence of factors like load-bearing cross-sectional area, screw angulation and bone mineral density upon implant stability should be investigated., Summary of Background Data: Epidemiologic data predict a growing demand for appropriate anterior spinal fixation devices especially in patients with inferior structural and mechanical bone properties. Although different concepts for anterior spinal instrumentation systems have been tried out, implant stability is still a problem., Methods: Three angular stable, anterior spinal implants were tested using 24 human lumbar osteoporotic vertebrae (L1-L5; age 84 (73-92)): MASC TL system (Aesculap); prototype 1 (MP1) with 18 degrees and prototype 2 (MP2) with 40 degrees screw angulation (both Synthes). All implants consisted of two screws with different outer screw diameters: 7-mm polyaxial screw with 6.5-mm stabilization screw (MASC TL), two 5-mm locking-head screws each (MP1 and MP2). Bone mineral density (BMD) and vertebral body width of the three specimen groups were evenly distributed. The specimens were loaded in craniocaudal direction (1Hz) for 1000 cycles each at three consecutive load steps; 10-100 N, 10-200 N and 10-400 N. During cyclic loading subsidence of the implant relative to the vertebral body was measured in the unloaded condition. Cycle number at failure (defined as a subsidence of 2 mm) was determined for each specimen. A survival analysis (Cox Regression) was performed to detect differences between implant groups at a probability level of 95%., Results: High correlations were found between BMD and number of cycles until failure (MP1; r = 0.905, P = 0.013; MP2: r = 0.640, P = 0.121; MACS TL: r = 0.904, P = 0.013) and between load bearing cross sectional area and number of cycles until failure (MP1: r = 0.849, P = 0.032;MP2: r = 0.692, P = 0.085; MACS TL: r = 0.902, P = 0.014). Both Prototypes survived significantly longer than the MACS TL implant (MP1: P = 0.012, MP2: P = 0.014). The survival behaviour of MP1 and MP2 was not significantly different (P = 0.354)., Conclusions: Implant stability within each implant group was influenced by BMD and load bearing cross-sectional area. The angulation of the two screws did not have a significant influence on cut-out. As conclusion from this study, promising approaches for further implant development are: 1) increase of load-bearing cross-sectional area (e.g., larger outer diameter of the anchorage device), 2) screw positioning in areas of higher BMD (e.g., opposite cortex, proximity to pedicles or the endplates).

Background: Aim of this in-vitro study was to compare the hip cup placement for total hip replacement when using different navigation systems compared with the traditional, non-navigated technique., Methods: Five different navigation systems were used: the CT-less systems Navitrack, Orthopilot and Surgetics Station, as well as the CT-based Navitrack and VectorVision. Three different surgeons carried out five cup implantations using all navigation systems and the manual approach on a surgery dummy. Cup orientation (inclination and anteversion) and the cup position (achieved cup center) were determined with a coordinate measuring machine., Results: In the manual group the variability of the cup orientation was higher in comparison and hardly influenced by the surgeon. Navigation was identified as a significant factor for smaller deviations from planned inclination and anteversion angles (p<0,001 for both). Cup position was not affected by surgeon in the manual group (p=0,966). Compared with manual technique, the cup misplacement vector was significantly smaller in the CT-Navitrack group (p<0,001) but higher in the Navitrack (CT-less) and VectorVision group (p<0,001)., Conclusions: The use of computer navigation will help the surgeon to orientate the acetabular component more accurately but not necessarily with regard to cup positioning.

Fractures of the bones of elderly people occur more often and have a more important effect because of a generally diminished ability to coordinate stance and walking. These fractures occur at a lower level of load because of lack of strength of the porotic bone. Prompt recovery of skeletal support function is essential to avoid respiratory and circulatory complications in the elderly. To prevent elderly people from the risks of being bedridden, demanding internal fixation of fractures is required. The weak porotic bone and the high level of uncontrolled loading after internal fixation pose complex problems. A combination of several technical elements of design, application and aftercare in internal fixation are proposed. Internal fixators with locked screws improve the biology and the mechanics of internal fixation. When such fixators are used as elevated splints they may stimulate early callus formation because of their flexibility, the limit of flexibility being set by the demands of resistance and function of the limb. Our own studies of triangulation of locked screws have demonstrated their beneficial effects and unexpected limitations.

The quality of bone cuts is assessed by the accuracy and biological potency of the cut surfaces. Conventional tools (such as saws and milling machines) can cause thermal damage to bone tissue. Water jet cutting is nonthermal; that is, it does not generate heat. This study investigates whether the abrasive jet cutting quality in cancellous bone with a biocompatible abrasive is sufficient for the implantation of endoprostheses or for osteotomies. Sixty porcine femoral condyles were cut with an abrasive water jet and with an oscillating saw. alpha-lactose-monohydrate was used as a biocompatible abrasive. Water pressure (pW = 35 and 70 MPa) and abrasive feed rate (m = 0.5, 1, and 2 g/s) were varied. As a measure of the quality of the cut surface the cutting gap angle (delta) and the surface roughness (Ra) were determined. The surface roughness was lowest for an abrasive feed rate of m = 2 g/s (jet direction: 39 +/- 16 microm, advance direction: 54 +/- 22 microm). However, this was still significantly higher than the surface roughness for the saw group (jet direction: 28 +/- 12 microm, advance direction: 36 +/- 19 microm) (p < 0.001 for both directions). At both pressure levels the greatest cutting gap angle was observed for a mass flow rate of m = 1 g/s (pW = 35 MPa: delta = 2.40 +/- 4.67 degrees ; pW = 70 MPa: delta = 4.13 +/- 4.65 degrees), which was greater than for m = 0.5 g/s (pW = 35 MPa: delta = 1.63 +/- 3.89 degrees ; pW = 70 MPa: delta = 0.36 +/- 1.70 degrees) and m = 2 g/s (pW =70 MPa: delta = 0.06 +/- 2.40 degrees). Abrasive water jets are suitable for cutting cancellous bone. The large variation of the cutting gap angle is, however, unfavorable, as the jet direction cannot be adjusted by a predefined value. If it is possible to improve the cutting quality by a further parameter optimization, the abrasive water jet may be the cutting technique of the future for robotic usage., ((c) 2004 Wiley Periodicals, Inc.)

Working on bone is a major aspect of orthopaedic surgery. Despite its well-known appreciable thermal effects on the edges of the bone cut, the oscillating bone saw blade the oscillating saw remains the standard instrument both for cutting long bones and creating a bed for an endoprosthesis. The application of abrasive water jets offers the possibility of achieving an extremely precise curved cut in bone with no accompanying thermal effect. The thermographically measured absolute temperature increase at the cut edges seen with the water jet was 13 K maximum. The small process forces permit the application in automated handling systems.

Conventional tools used in prosthetic revision surgery have a limited range of action within the narrow cement mantle. Water jet cutting technology permits tiny and precisely controlled cuts, and may therefore be an alternative method of bone cement removal. Our study compares the cutting performance on bone cement (PMMA) and bone of a pulsed water jet and a continuous water jet. The aim of the study was to establish whether selective removal of PMMA is possible. 55 bone specimens (bovine femora) and 32 specimens of PMMA were cut with a continuous and a pulsed water jet at different pressures (40 MPa, 60 MPa) and pulse frequencies (0Hz, 50Hz, 250Hz). To ensure comparability of the results, the depths of cut were related to the hydraulic power of that part of the jet actually impinging on the material. While for PMMA the power-related depth of cut increased significantly with the pulse frequency, this did not apply to bone. The cuts produced in bone were sharp-edged. Since PMMA is more brittle than bone, the water jet caused cracks that enlarged further until particles of bone broke away. Although selective removal of PMMA without doing damage to the bone was not possible at the investigated settings of the jet parameters, the results do show that a pulsed water jet can cut bone cement much more effectively than bone. This is an important advantage over conventional non-selective tools for the removal of bone cement.