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52. Outcomes with Finerenone in Participants with Stage 4 CKD and Type 2 Diabetes: A FIDELITY Subgroup Analysis
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Sarafidis, Pantelis, Agarwal, Rajiv, Pitt, Bertram, Wanner, Christoph, Filippatos, Gerasimos, Boletis, John, Tuttle, Katherine R., Ruilope, Luis M., Rossing, Peter, Toto, Robert, Anker, Stefan D., Liu, Zhi-Hong, Joseph, Amer, Ahlers, Christiane, Brinker, Meike, Lawatscheck, Robert, Bakris, George, Aizenberg, Diego, Bartolacci, Inés, Besada, Diego, Bittar, Julio, Chahin, Mariano, Elbert, Alicia, Gelersztein, Elizabeth, Liberman, Alberto, Maffei, Laura, Manghi, Federico Pérez, Sanabria, Hugo, Vallejos, Augusto, Viñes, Gloria, Wassermann, Alfredo, Abhayaratna, Walter, Acharya, Shamasunder, Ekinci, Elif, Lee, Darren, MacIsaac, Richard, Mah, Peak Mann, Nelson, Craig, Packham, David, Pape, Alexia, Roger, Simon, Stephenson, Hugo, Suranyi, Michael, Wittert, Gary, Vale, Elizabeth, Colman, Peter, Colquhoun, David, Ellis, Chris, Joshua, Kim, Pedagogos, Eugenia, Regal, Paul, Topliss, Duncan, Vandeleur, James, Verjans, Johan, Wittert, Gary, Wynne, Katie-Jane, Clodi, Martin, Ebenbichler, Christoph, 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Adler, Sharon, Ajani, Dilawar, Ali, Slamat, Alicic, Radica, Al-Karadsheh, Amer, Alla, Sreedhara, Allison, D., Andrawis, Nabil, Arif, Ahmed, Awad, Ahmed, Azizad, Masoud, Bahrami, Michael, Bansal, Shweta, Barag, Steven, Barakzoy, Ahmad, Barney, Mark, Barzilay, Joshua, Bashir, Khalid, Bautista, Jose, Beddhu, Srinivasan, Belo, Diogo, Benjamin, Sabrina, Berenji, Ramin, Bhargava, Anuj, Birriel, Jose, Brietzke, Stephen, Brosius, Frank, Brusco, Osvaldo, Burgner, Anna, Busch, Robert, Canadas, Rafael, Caramori, Maria, Cardona, Jose, Case, Christopher, Cruz, Humberto, Dandillaya, Ramprasad, Dawoud, Dalia, Din, Zia, Dixon, Bradley, Doshi, Ankur, Drakakis, James, El Shahawy, Mahfouz, El-Meanawy, Ashraf, El-Shahawy, Mohammed, Evans, John, Fadda, George, Farooq, Umar, Fernando, Roland, Fink, Raymond, First, Brian, Fitz-Patrick, David, Flack, John, Fluck, Patrick, Fogelfeld, Leon, Fonseca, Vivian, Frias, Juan, Galphin, Claude, Garcia-Mayol, Luis, Goldstein, Gary, Gonzalez, Edgar, Gonzalez-Abreu, Francisco, Gore, Ashwini, Grant, David, Habwe, Violet, Hamilton, Maxine, Hammoud, Jamal, Handelsman, Stuart, Hartman, Israel, Heigerick, Glenn, Henry, Andrew, Hernandez, German, Hernandez-Cassis, Carlos, Herrera, Carlos, Hertel, Joachim, Huang, Wenyu, Iglesias, Rogelio, Iranmanesh, Ali, Jackson, Timothy, Jain, Mahendra, Jamerson, Kenneth, Johnson, Karen, Judd, Eric, Kaplan, Joshua, Kayali, Zeid, Khan, Bobby, Khan, Muhammad, Kharait, Sourabh, Kirkman, M. Sue, Kopyt, Nelson, Kotzker, Wayne, Kovesdy, Csaba, Kreit, Camil, Krishna, Arvind, Kronfli, Saeed, Lee, Keung, LeJeune, Derek, Lemus, Brenda, Leon-Forero, Carlos, Linfert, Douglas, Lora, Henry, Lurie, Alexander, Maddukuri, Geetha, Magno, Alexander, Maletz, Louis, Mandayam, Sreedhar, Markell, Mariana, Mayfield, Ronald, Mbogua, Caroline, McMullen, Dierdre, Meisner, Carl, Minton, Stephen, Mocherla, Bharat, Mohandas, Rajesh, Montero, Manuel, Moustafa, Moustafa, Nadkarni, Salil, Nakhle, Samer, Navarro, Jesus, Neyra, Nilda, Nica, Romanita, Nicol, Philip, Norwood, Paul, Numrungroad, Visal, Donovan, Richard O′, Odugbesan, A., Paoli-Bruno, Jorge, Parikh, Samir, Patel, Rakesh, Peixoto, Aldo, Pergola, Pablo, Perlman, Alan, Pettis, Karlton, Pisoni, Roberto, Ponduchi, Mirela, Posada, Jorge, Prabhakar, Sharma, Radhakrishnan, Jai, Rahman, Mahboob, Raina, Rupesh, Rastogi, Anjay, Reisin, Efrain, Rendell, Marc, Robertson, David, Rocco, Michael, Romeu, Hugo, Rosas, Sylvia, Rosenfeld, Jack, Ross, Dennis, Rothman, Jeffrey, Rudolph, Lance, Ruhullah, Yusuf, Ruoff, Gary, Ryu, Jeffrey, Sahani, Mandeep, Sam, Ramin, Samuels, Garfield, Sanchez, William, Santos, Vladimir, Satko, Scott, Saxena, Sanjeev, Scott, David, Seco, Gilberto, Seek, Melvin, Serota, Harvey, Shafi, Tariq, Shahid, Nauman, Shanik, Michael, Sharma, Santosh, Sinha, Arjun, Smelser, James, Smith, Mark, Soe, Kyaw, Solomon, Richard, Soroka, Eugene, Soufer, Joseph, Spinowitz, Bruce, Spry, Leslie, Suarez, Rosa, Subramanian, Bala, Szerlip, Harold, Tamirisa, Aparna, Thomson, Stephen, Tran, Tuan-Huy, Treger, Richard, Trullenque, Gretel, Turk, Thomas, Umpierrez, Guillermo, Urbach, Daniel, Valdes, Martin, Valika, Shujauddin, Vega, Damaris, Weissman, Peter, Whaley-Connell, Adam, Winston, Jonathan, Wise, Jonathan, Wynne, Alan, Zeig, Steven, Abdel-Rahman, Emaad, Abreu, Edel, Awad, Alaa, Bahri, Nader, Bertsch, John, Bleich, David, Bornfreund, Jonathan, Brar, Harjeet, Brian, Susan, Brinson, Cynthia, Bruschetta, Humberto, Carpio, Jose, Cohen, Steven, Cosby, John, Dhanireddy, Soni, Diaz, Jorge, Dunn, Fredrick, Eppanapally, Sabitha, Fayad, Joseph, Goel, Archana, Govindaraju, Kanakadurga, Halpern, Stephen, Jones, Audrey, Kaye, William, Knight, Herbert, Koch, Stanley, Kohli, Nandini, Lastra, Guido, Lerman, Sam, Loredo, Jorge, Lovre, Dragana, Mandviwala, Mustafa, Martin, Earl, Meyer, Jill, Murray, John, Oliver, David, Oparil, Suzanne, Penabad, Jesus, Pereira, Isabel, Popeil, Larry, Quesada, Gonzalo, Ramanathan, Kodangudi, Ramos-Gonez, Luis, Rastegar, Mandana, Rastogi, Padmashri, Rondon, Juan, Roy-Chaudhury, Prabir, Smith, David, Williamson, Don, Womack, Catherine, Yamout, Hala, Yuryev, Michael, Chu, Phuong, Van Hoang, Lam, Khanh, Tran, Phi Nga, Nguyen Thi, Son, Pham Nguyen, Tran, Lan Phuong, Le, Thuy Khuong, Nguyen, Boi Ngoc, Nguyen, Thao, Nui, Nguyen Minh, Nam, Tran Quang, and Tran, Kim Chi
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- 2023
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53. The Effect and Prevalence of Comorbidities in Adolescents With CKD and Obesity
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Nair, Nikhil, Kalra, Riti, Chandra Bhatt, Girish, Narang, Aarushi, Kumar, Gurinder, and Raina, Rupesh
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- 2022
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54. Advances in pediatric acute kidney injury
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Raina, Rupesh, Chakraborty, Ronith, Tibrewal, Abhishek, Sethi, Sidharth K., and Bunchman, Timothy
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- 2022
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55. Complement Inhibition in Severe S. pneumoniae–Associated Hemolytic Uremic Syndrome
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Sethi, Sidharth Kumar, Raina, Rupesh, Dhaliwal, Maninder, Raghunathan, Veena, Bansal, Shyam Bihari, Taneja, Satvika, and Bagga, Arvind
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- 2023
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56. Correction: Neonatal acute kidney injury risk stratification score: STARZ study
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Wazir, Sanjay, Sethi, Sidharth Kumar, Agarwal, Gopal, Tibrewal, Abhishek, Dhir, Rohan, Bajaj, Naveen, Gupta, Naveen Parkash, Mirgunde, Shishir, Sahoo, Jagdish, Balachandran, Binesh, Afzal, Kamran, Shrivastava, Anubha, Bagla, Jyoti, Krishnegowda, Sushma, Konapur, Ananth, Soni, Kritika, Rana, Abhyuday, Bunchman, Timothy, and Raina, Rupesh
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- 2022
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57. Management of Intoxications in Pediatrics
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Raina, Rupesh, Lam, Stephanie, Raheja, Hershita, Bestic, Michelle, Blackford, Martha, Sethi, Sidharth Kumar, editor, Raina, Rupesh, editor, McCulloch, Mignon, editor, and Bunchman, Timothy E., editor
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- 2019
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58. Vascular Access in a Child with Acute Kidney Injury
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Chand, Deepa, Raina, Rupesh, Sethi, Sidharth Kumar, editor, Raina, Rupesh, editor, McCulloch, Mignon, editor, and Bunchman, Timothy E., editor
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- 2019
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59. Hemodialysis Treatment Prescription
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Raina, Rupesh, Krishnappa, Vinod, Sethi, Sidharth Kumar, editor, Raina, Rupesh, editor, McCulloch, Mignon, editor, and Bunchman, Timothy E., editor
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- 2019
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60. Point-of-care-Ultrasound (POCUS) Training Curriculum for Pediatric Nephrology: PCRRT-ICONIC Group Recommendations
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Sethi, Sidharth Kumar, primary, Mahan, John, additional, Hu, Jieji, additional, Koratala, Abhilash, additional, Soni, Kritika, additional, Singh, Yogen, additional, Abitbol, Carolyn, additional, DeFreitas, Marissa, additional, Reisinger, Nathaniel, additional, Argaiz, Eduardo R, additional, Yap, Hui Kim, additional, Badeli, Hamidreza, additional, Kalra, Meenal, additional, VanGeest, Jonathan, additional, Nair, Nikhil, additional, Raynor, James, additional, Alhasan, Khalid A, additional, McCulloch, Mignon, additional, Bunchman, Timothy, additional, Sharma, Vivek, additional, and Raina, Rupesh, additional
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- 2024
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61. Health‐related quality of life for pediatric patients with end‐stage kidney disease: A systematic review and meta‐analysis of the Pediatric Quality of Life Inventory (PedsQL)
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Doshi, Kush, primary, Raina, Rupesh, additional, Ng, Kar Hui, additional, Koch, Vera, additional, Bhatt, Girish C., additional, Nada, Arwa, additional, Foresi, Brian, additional, Kamalakkannan, Sibee Sambandam, additional, McCulloch, Mignon, additional, Sethi, Sidharth, additional, and de Ferris, Maria Díaz‐González, additional
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- 2024
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62. The Case | Neonatal seizures and tubular dysfunction in childhood: joining the dots!
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Sethi, Sidharth Kumar, primary, Hu, Jieji, additional, and Raina, Rupesh, additional
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- 2024
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63. Critical analysis of acute kidney injury in pediatric COVID-19 patients in the intensive care unit
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Raina, Rupesh, Chakraborty, Ronith, Mawby, Isabelle, Agarwal, Nirav, Sethi, Sidharth, and Forbes, Michael
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Acute renal failure -- Diagnosis -- Risk factors ,Pediatric research ,Health - Abstract
Background and objectives COVID-19 is responsible for the 2019 novel coronavirus disease pandemic. Despite the vast research about the adult population, there has been little data collected on acute kidney injury (AKI) epidemiology, associated risk factors, treatments, and mortality in pediatric COVID-19 patients admitted to the ICU. AKI is a severe complication of COVID-19 among children and adolescents. Methods A comprehensive literature search was conducted in PubMed/MEDLINE and Cochrane Center Trials to find all published literature related to AKI in COVID-19 patients, including incidence and outcomes. Results Twenty-four studies reporting the outcomes of interest were included. Across all studies, the overall sample size of COVID positive children was 1,247 and the median age of this population was 9.1 years old. Among COVID positive pediatric patients, there was an AKI incidence of 30.51%, with only 0.56% of these patients receiving KRT. The mortality was 2.55% among all COVID positive pediatric patients. The incidence of multisystem inflammatory syndrome in children (MIS-C) among COVID positive patients was 74.29%. Conclusion AKI has shown to be a negative prognostic factor in adult patients with COVID-19 and now also in the pediatric cohort with high incidence and mortality rates. Additionally, our findings show a strong comparison in epidemiology between adult and pediatric COVID-19 patients; however, they need to be confirmed with additional data and studies. Graphical abstract, Author(s): Rupesh Raina [sup.1] [sup.2] [sup.3] , Ronith Chakraborty [sup.1] [sup.2] , Isabelle Mawby [sup.1] , Nirav Agarwal [sup.1] , Sidharth Sethi [sup.4] , Michael Forbes [sup.5] Author Affiliations: (1) [...]
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- 2021
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64. Survey of Telemedicine by Pediatric Nephrologists During the COVID-19 Pandemic
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Raina, Rupesh, Nair, Nikhil, Yap, Hui Kim, Filler, Guido, Sethi, Sidharth K., Bagga, Arvind, Hari, Pankaj, Bunchman, Timothy, Bartosh, Sharon, Twombley, Katherine, Kapur, Gaurav, McCulloch, Mignon, Warady, Bradley A., Díaz-González de Ferris, Maria, and Rush, Sarah
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- 2021
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65. Long-Term Renal Outcomes in Children With Acute Kidney Injury Post Cardiac Surgery
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Sethi, Sidharth Kumar, Sharma, Rajesh, Gupta, Aditi, Tibrewal, Abhishek, Akole, Romel, Dhir, Rohan, Soni, Kritika, Bansal, Shyam Bihari, Jha, Pranaw Kumar, Bhan, Anil, Kher, Vijay, and Raina, Rupesh
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- 2021
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66. A rare complication of pauci-immune crescentic glomerulonephritis in a child: Answers
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Sethi, Sidharth Kumar, Rana, Abhyuday, Bansal, Shyam Bihari, Rana, Alka, Yadav, Dinesh Kumar, Soni, Kritika, Dragon-Durey, Marie-Agnès, Raina, Rupesh, and Kher, Vijay
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- 2021
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67. Telemedicine for Pediatric Nephrology: Perspectives on COVID-19, Future Practices, and Work Flow Changes
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Yap, Hui Kim, Sethi, Sidharth K., Bagga, Arvind, Hari, Pankaj, Bunchman, Timothy, Bartosh, Sharon, Twombley, Katherine, Kapur, Gaurav, McCulloch, Mignon, Filler, Guido, Warady, Bradley A., Díaz-González de Ferris, Maria, Raina, Rupesh, Nair, Nikhil, Sharma, Aditya, Chakraborty, Ronith, and Rush, Sarah
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- 2021
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68. Evolution and change in paradigm of hemodialysis in children: a systematic review
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Chanchlani, Rahul, Young, Claire, Farooq, Aisha, Sanger, Stephanie, Sethi, Sidharth, Chakraborty, Ronith, Tibrewal, Abhishek, and Raina, Rupesh
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Hemodialysis -- Research -- Methods -- Patient outcomes ,Pediatric research ,Health - Abstract
Background There are similarities in hemodialysis (HD) between adults and children and also unique pediatric aspects. In this systematic review, we evaluated the existing HD literature, including vascular access, indications, parameters, and outcomes as a reflection on real-life HD practices. Methods Medline, Embase, CINAHL, Web of Science, and Cochrane Library were systematically searched for literature on HD in children (1-20 years). Two reviewers independently assessed the literature and data on indications; vascular access, outcomes, and specific parameters for HD were extracted. Results Fifty-four studies (8751 patients) were included in this review. Studies were stratified into age groups 1-5, 6-12, and 13-20 years based on median/mean age reported in the study, as well as era of publication (1990-2000, 2001-2010, and 2011-2019). Across all age groups, both arteriovenous fistulas and central venous catheters were utilized for vascular access. Congenital abnormalities and glomerulopathy were the most common HD indications. HD parameters including HD session duration, dialysate and blood flow rates, urea reduction ratio, and ultrafiltration were characterized for each age group, as well as common complications including catheter dysfunction and intradialytic hypotension. Median mortality rates were 23.3% (3.3), 7.6% (14.5), and 2.0% (3.0) in ages 1-5, 6-12, and 13-20 years, respectively. Median transplantation rates were 41.6% (38.3), 52.0% (32.0), and 21% (25.6) in ages 1-5, 6-12, and 13-20, respectively. Conclusion This comprehensive systematic review summarizes available literature on HD in children and young adults, including best vascular access, indications, technical aspects, and outcomes, and reflects on HD practices over the last three decades., Author(s): Rahul Chanchlani [sup.1] [sup.2] , Claire Young [sup.3] , Aisha Farooq [sup.3] , Stephanie Sanger [sup.3] , Sidharth Sethi [sup.4] , Ronith Chakraborty [sup.5] , Abhishek Tibrewal [sup.6] , [...]
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- 2021
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69. Advances in Kidney Replacement Therapy in Infants
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Raina, Rupesh, McCulloch, Mignon, Nourse, Peter, Sethi, Sidharth K., and Yap, Hui Kim
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- 2021
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70. What came first, atypical hemolytic uremic syndrome or malignant hypertension: a clinical dilemma.
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Sethi, Sidharth Kumar, S, Savita, Nair, Aishwarya, Soni, Kritika, Bihari Bansal, Shyam, Rana, Abhyuday S., and Raina, Rupesh
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HEMOLYTIC-uremic syndrome ,HYPERTENSION ,THROMBOTIC thrombocytopenic purpura ,HYPERTENSIVE crisis ,OPTIC disc edema ,LEFT ventricular hypertrophy ,DILEMMA - Abstract
This article discusses a case study of a 7-year-old girl who presented with a hypertensive crisis and thrombotic microangiopathy (TMA). The study found that severe hypertension led to TMA in this case, which is rare in children. The patient was treated with intravenous eculizumab and antihypertensive agents, which resulted in improvement in her condition. The article emphasizes the importance of evaluating hypertension-associated TMA for complement defects and initiating aggressive hypertension control and targeted therapies for better outcomes. It also highlights the potential association between severe hypertension and TMA, and the role of complement activation in the pathogenesis. [Extracted from the article]
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- 2024
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71. Siblings with complement activation, thrombotic microangiopathy and gangrene: Answers
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Sethi, Sidharth Kumar, Dhaliwal, Maninder, Raghunathan, Veena, Raaj, Hritik, Mahato, Samit Kumar, Vadhera, Ananya, Dragon-Durey, Marie-Agnes, Jha, Pranaw Kumar, Bansal, Shyam Bihari, and Raina, Rupesh
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- 2022
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72. Familial kidney failure with macro-thrombocytopenia: Questions
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Sethi, Sidharth Kumar, Goel, Shalini, Vadhera, Ananya, Raaj, Hritik, Mahato, Samit Kumar, Jha, Pranaw, Bansal, Shyam, and Raina, Rupesh
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- 2022
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73. Autosomal-dominant polycystic kidney disease: tolvaptan use in adolescents and young adults with rapid progression
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Raina, Rupesh, Chakraborty, Ronith, DeCoy, Meredith E., and Kline, Timothy
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- 2021
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74. Using artificial intelligence to predict mortality in AKI patients: a systematic review/meta-analysis.
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Raina, Rupesh, Shah, Raghav, Nemer, Paul, Fehlmen, Jared, Nemer, Lena, Murra, Ali, Tibrewal, Abhishek, Sethi, Sidharth Kumar, Neyra, Javier A, and Koyner, Jay
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ARTIFICIAL intelligence , *MACHINE learning , *ACUTE kidney failure , *HOSPITAL mortality , *MORTALITY - Abstract
Background Acute kidney injury (AKI) is associated with increased morbidity/mortality. With artificial intelligence (AI), more dynamic models for mortality prediction in AKI patients have been developed using machine learning (ML) algorithms. The performance of various ML models was reviewed in terms of their ability to predict in-hospital mortality for AKI patients. Methods A literature search was conducted through PubMed, Embase and Web of Science databases. Included studies contained variables regarding the efficacy of the AI model [the AUC, accuracy, sensitivity, specificity, negative predictive value and positive predictive value]. Only original studies that consisted of cross-sectional studies, prospective and retrospective studies were included, while reviews and self-reported outcomes were excluded. There was no restriction on time and geographic location. Results Eight studies with 37 032 AKI patients were included, with a mean age of 65.3 years. The in-hospital mortality was 18.0% in the derivation and 15.8% in the validation cohorts. The pooled [95% confidence interval (CI)] AUC was observed to be highest for the broad learning system (BLS) model [0.852 (0.820–0.883)] and elastic net final (ENF) model [0.852 (0.813–0.891)], and lowest for proposed clinical model (PCM) [0.765 (0.716–0.814)]. The pooled (95% CI) AUC of BLS and ENF did not differ significantly from other models except PCM [Delong's test P = .022]. PCM exhibited the highest negative predictive value, which supports this model's use as a possible rule-out tool. Conclusion Our results show that BLS and ENF models are equally effective as other ML models in predicting in-hospital mortality, with variability across all models. Additional studies are needed. [ABSTRACT FROM AUTHOR]
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- 2024
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75. Prevention of dialysis disequilibrium syndrome in children with advanced uremia with a structured hemodialysis protocol: A quality improvement initiative study.
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Sethi, Sidharth Kumar, Luyckx, Valerie, Bunchman, Timothy, Nair, Aishwarya, Bansal, Shyam Bihari, Pember, Bryce, Soni, Kritika, Savita, Yadav, Dinesh Kumar, Sharma, Vivek, Alhasan, Khalid, and Raina, Rupesh
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SYNDROMES in children ,DIALYSIS (Chemistry) ,HEMODIALYSIS ,UREMIA ,CHILD patients - Abstract
Background: Dialysis disequilibrium syndrome (DDS) is a rare but significant concern in adult and pediatric patients undergoing dialysis initiation with advanced uremia or if done after an interval. It is imperative to gain insights into the epidemiological patterns, pathophysiological mechanisms, and preventive strategies aimed at averting the onset of this ailment. Design: Prospective observational quality improvement initiative cohort study. Setting and Participants: A prospective single‐center study involving 50 pediatric patients under 18 years recently diagnosed with chronic kidney disease stage V with blood urea ≥200 mg/dL, admitted to our tertiary care center for dialysis initiation from January 2017 to October 2023. Quality Improvement Plan: A standardized protocol was developed and followed for hemodialysis in pediatric patients with advanced uremia. This protocol included measures such as lower urea reduction ratios (targeted at 20%–30%) with shorter dialysis sessions and linear dialysate sodium profiling. Prophylactic administration of mannitol and 25% dextrose was also done to prevent the incidence of dialysis disequilibrium syndrome. Measures: Incidence of dialysis disequilibrium syndrome and severe dialysis disequilibrium syndrome, mortality, urea reduction ratios (URRs), neurological outcome at discharge, and development of complications such as infection and hypotension. Long‐term outcomes were assessed at the 1‐year follow‐up including adherence to dialysis, renal transplantation, death, and loss to follow‐up. Results: The median serum creatinine and urea levels at presentation were 7.93 and 224 mg/dL, respectively. A total of 20% of patients had neurological symptoms attributable to advanced uremia at the time of presentation. The incidence of dialysis disequilibrium syndrome was 4% (n = 2) with severe dialysis disequilibrium syndrome only 2% (n = 1). Overall mortality was 8% (n = 4) but none of the deaths were attributed to dialysis disequilibrium syndrome. The mean urea reduction ratios for the first, second, and third dialysis sessions were 23.45%, 34.56%, and 33.50%, respectively. The patients with dialysis disequilibrium syndrome were discharged with normal neurological status. Long‐term outcomes showed 88% adherence to dialysis and 38% renal transplantation. Limitations: This study is characterized by a single‐center design, nonrandomized approach, and limited sample size. Conclusions: Our structured protocol served as a framework for standardizing procedures contributing to low incidence rates of dialysis disequilibrium syndrome. [ABSTRACT FROM AUTHOR]
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- 2024
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76. Challenges of Vascular Access in the Pediatric Population
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Raina, Rupesh, Mittal, Aliza, Sethi, Sidharth Kumar, and Chakraborty, Ronith
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- 2020
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77. Nutrition in Critically Ill Children with Acute Kidney Injury on Continuous Kidney Replacement Therapy: An Integrative Review and Clinical Practice Points 2023
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Raina, Rupesh, primary, Suchan, Andrew, additional, Sethi, Sidharth K, additional, Soundararajan, Anvitha, additional, Vitale, Victoria S, additional, Keller, Gerri L, additional, Brown, Ann-Marie, additional, Davenport, Andrew, additional, Shih, Weiwen V, additional, Nada, Arwa, additional, Irving, Sharon Y, additional, Mannemuddhu, Sai Sudha, additional, Crugnale, Aylin S, additional, Myneni, Archana, additional, Berry, Katarina G, additional, Zieg, Jakub, additional, Alhasan, Khalid, additional, Guzzo, Isabella, additional, Lussier, Natalie H, additional, Yap, Hui Kim, additional, and Bunchman, Timothy E, additional
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- 2023
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78. Insight into prevalence, etiology, and modalities of pediatric chronic dialysis: a comprehensive nationwide analysis
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Alhasan, Khalid, primary, Alsalmi, Amro Attaf, additional, Almaiman, Weiam, additional, Al Herbish, Adi J., additional, Farhat, Afrah, additional, Sandokji, Ibrahim, additional, Aloufi, Majed, additional, Faqeehi, Hassan Yahya, additional, Abdulmajeed, Naif, additional, Alanazi, Abdulkarim, additional, AlHassan, Abdulaziz, additional, Alshathri, Abdulaziz, additional, Almalki, Abeer Mohammad, additional, Bafageeh, Afaf Alawi, additional, Aldajani, Ali M., additional, AlMuzain, Ashraf, additional, Almuteri, Faten Sudan, additional, Nasser, Haydar Hassan, additional, Al Alsheikh, Khalid, additional, Almokali, Khamisa Mohamed, additional, Maghfuri, Magbul, additional, Abukhatwah, Mohamed Waleed, additional, Ahmed, Muawia Abdulla Mohamed, additional, Fatani, Naeima, additional, Al-Harbi, Naffaa, additional, AlDhaferi, Rezqah Fajor, additional, Amohaimeed, Sulaiman, additional, AlSannaa, Zahra Hussain, additional, Shalaby, Mohamed A., additional, Raina, Rupesh, additional, Broering, Dieter Clemens, additional, Kari, Jameela A., additional, and Temsah, Mohamad-Hani, additional
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- 2023
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79. Post-transplant Recurrence of Focal Segmental Glomerulosclerosis: Consensus Statements
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Raina, Rupesh, primary, Jothi, Swathi, additional, Haffner, Dieter, additional, Somers, Michael, additional, Filler, Guido, additional, Vasistha, Prabhav, additional, Chakraborty, Ronith, additional, Shapiro, Ron, additional, Randhawa, Parmjeet S., additional, Parekh, Rulan, additional, Licht, Christopher, additional, Bunchman, Timothy, additional, Sethi, Sidharth, additional, Mangat, Guneive, additional, Zaritsky, Joshua, additional, Schaefer, Franz, additional, Warady, Bradley, additional, Bartosh, Sharon, additional, McCulloch, Mignon, additional, Alhasan, Khalid, additional, Swiatecka-Urban, Agnieszka, additional, Smoyer, William E., additional, Chandraker, Anil, additional, Yap, Hui Kim, additional, Jha, Vivekananda, additional, Bagga, Arvind, additional, and Radhakrishnan, Jai, additional
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- 2023
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80. Economic Burden of the Stages of Pediatric CKD on the US Healthcare System
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Taliwal, Neal, primary, Pandya, Aadi, additional, Dixon, Angelina, additional, Tibrewal, Abhishek, additional, Kumar, Rohan J, additional, Doshi, Kush, additional, Warady, Bradley A, additional, and Raina, Rupesh, additional
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- 2023
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81. Kidney Replacement Therapy and Mortality in Children With Inborn Errors of Metabolism: A Meta-analysis
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Raina, Rupesh, primary, Doshi, Kush, additional, Sethi, Sidharth, additional, Pember, Bryce, additional, Kumar, Rohan, additional, Alhasan, Khalid A., additional, Boshkos, Mitchell C., additional, Tibrewal, Abhishek, additional, and Bedoyan, Jirair K., additional
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- 2023
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82. Artificial intelligence in early detection and prediction of pediatric/neonatal acute kidney injury: current status and future directions
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Raina, Rupesh, primary, Nada, Arwa, additional, Shah, Raghav, additional, Aly, Hany, additional, Kadatane, Saurav, additional, Abitbol, Carolyn, additional, Aggarwal, Mihika, additional, Koyner, Jay, additional, Neyra, Javier, additional, and Sethi, Sidharth Kumar, additional
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- 2023
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83. Sudden Spurt in Pediatric Acute Kidney Injury Cases in Uzbekistan: A Call for International Drug Quality Control and Pharmaceutical Legislation
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Murtalibova, Nodira, primary, Sethi, Sidharth Kumar, additional, Raina, Rupesh, additional, Mamatkulov, Bahrom, additional, and Mustakimov, Alisher, additional
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- 2023
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84. Voice of a caregiver: call for action for multidisciplinary teams in the care for children with atypical hemolytic uremic syndrome
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Burke, Linda, primary, Sethi, Sidharth Kumar, additional, Boyer, Olivia, additional, Licht, Christoph, additional, McCulloch, Mignon, additional, Shah, Raghav, additional, Luyckx, Valerie A., additional, and Raina, Rupesh, additional
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- 2023
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85. 1338: FAILURE OF THERAPEUTIC PLASMA EXCHANGE IN ADULT SUICIDE BY SUBCUTANEOUS RICIN INJECTION
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Shaub, Timothy, Myers, Joseph, and Raina, Rupesh
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- 2022
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86. Renal replacement therapy in the management of intoxications in children: recommendations from the Pediatric Continuous Renal Replacement Therapy (PCRRT) workgroup
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Raina, Rupesh, Grewal, Manpreet K, Blackford, Martha, Symons, Jordan M., Somers, Michael J. G., Licht, Christoph, and Basu, Rajit K
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United States -- Conferences, meetings and seminars ,Children -- Health aspects ,Health - Abstract
Background Intentional or unintentional ingestions among children and adolescents are common. There are a number of ingestions amenable to renal replacement therapy (RRT). Methods We systematically searched PubMed/Medline, Embase, and Cochrane databases for literature regarding drugs/intoxicants and treatment with RRT in pediatric populations. Two experts from the PCRRT (Pediatric Continuous Renal Replacement Therapy) workgroup assessed titles, abstracts, and full-text articles for extraction of data. The data from the literature search was shared with the PCRRT workgroup and two expert toxicologists, and expert panel recommendations were developed. Results and Conclusions We have presented the recommendations concerning the use of RRTs for treatment of intoxications with toxic alcohols, lithium, vancomycin, theophylline, barbiturates, metformin, carbamazepine, methotrexate, phenytoin, acetaminophen, salicylates, valproic acid, and aminoglycosides., Author(s): Rupesh Raina [sup.1] [sup.2] , Manpreet K Grewal [sup.2] , Martha Blackford [sup.3] , Jordan M. Symons [sup.4] , Michael J. G. Somers [sup.5] , Christoph Licht [sup.6] , [...]
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- 2019
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- View/download PDF
87. An update on LDL apheresis for nephrotic syndrome
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Raina, Rupesh and Krishnappa, Vinod
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Nephrotic syndrome -- Diagnosis -- Care and treatment -- Development and progression ,Apheresis -- Methods -- Patient outcomes ,Low density lipoproteins -- Health aspects ,Health - Abstract
Low-density lipoprotein (LDL) apheresis has been used increasingly in clinical practice for the treatment of renal diseases with nephrotic syndrome (NS), specifically focal segmental glomerulosclerosis (FSGS). Persistent hyperlipidemia for prolonged periods is nephrotoxic and leads to chronic progressive glomerular and tubulointerstitial injury. Effective management of hyperlipidemia with HMG-CoA reductase inhibitors or LDL apheresis in drug-resistant NS patients may prevent the progression of renal disease and, in some patients, resolution of NS symptoms. Available literature reveals beneficial effects of LDL apheresis for NS refractory to drug therapy. Here we update on the current understanding of lipid nephrotoxicity and application of LDL apheresis to prevent progression of renal diseases., Author(s): Rupesh Raina [sup.1] [sup.2] , Vinod Krishnappa [sup.2] [sup.3] Author Affiliations: (Aff1) grid.413473.6, 0000 0000 9013 1194, Department of Pediatric Nephrology, Akron Children's Hospital, , Akron, OH, USA (Aff2) [...]
- Published
- 2019
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88. Consensus guidelines for management of hyperammonaemia in paediatric patients receiving continuous kidney replacement therapy
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Raina, Rupesh, Bedoyan, Jirair K., Lichter-Konecki, Uta, Jouvet, Philippe, Picca, Stefano, Mew, Nicholas Ah, Machado, Marcel C., Chakraborty, Ronith, Vemuganti, Meghana, Grewal, Manpreet K., Bunchman, Timothy, Sethi, Sidharth Kumar, Krishnappa, Vinod, McCulloch, Mignon, Alhasan, Khalid, Bagga, Arvind, Basu, Rajit K., Schaefer, Franz, Filler, Guido, and Warady, Bradley A.
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- 2020
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89. Renal Replacement Therapy in Pediatric Acute Kidney Injury
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Sethi, Sidharth Kumar, Chakraborty, Ronith, Joshi, Hirva, and Raina, Rupesh
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- 2020
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90. Pediatric Kidney Biopsy: Clinical Perspectives Based on Survey of Pediatric Nephrologists and Interventional Radiologists
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Nair, Nikhil, Varnell, Charles, Patel, Manish, VanGeest, Jonathan, Grinsell, Matt, Altemose, Kathleen, Sethi, Sidharth K., and Raina, Rupesh
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- 2024
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91. Capacity for the management of kidney failure in the International Society of Nephrology North America and the Caribbean region: report from the 2023 ISN Global Kidney Health Atlas (ISN-GKHA)
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Lowe-Jones, Racquel, Ethier, Isabelle, Fisher, Lori-Ann, Wong, Michelle M.Y., Thompson, Stephanie, Nakhoul, Georges, Sandal, Shaifali, Chanchlani, Rahul, Davison, Sara N., Ghimire, Anukul, Jindal, Kailash, Osman, Mohamed A., Riaz, Parnian, Saad, Syed, Sozio, Stephen M., Tungsanga, Somkanya, Cambier, Alexandra, Arruebo, Silvia, Bello, Aminu K., Caskey, Fergus J., Damster, Sandrine, Donner, Jo-Ann, Jha, Vivekanand, Johnson, David W., Levin, Adeera, Malik, Charu, Nangaku, Masaomi, Okpechi, Ikechi G., Tonelli, Marcello, Ye, Feng, Parekh, Rulan S., Anand, Shuchi, Agarwal, Anil K., Amouzegar, Atefeh, Avila-Casado, Carmen, Barton, Everard N., Behera, Suman, Felix, Melvin Bonilla, Cerda, Jorge, Cho, Yeoungjee, Cybulsky, Andrey V., Davids, M. Razeen, Diaz-González de Ferris, María Esther, Diongole, Hassane M., Divyaveer, Smita, Ekrikpo, Udeme E., Fogo, Agnes B., Friedman, David, Wing-Shing Fung, Winston, Furth, Susan L., Gill, John, Houston, Ghenette, Hsiao, Li-Li, Hsu, Chi-yuan, Htay, Htay, Ibrahim, Kwaifa Salihu, Irish, Georgina, Karam, Sabine, Kelly, Dearbhla M., Lalji, Rowena, Lerma, Edgar V., Mac-Way, Fabrice, Macedo, Etienne, Mohammed, Hassina, Nair, Devika, Nalado, Aisha M., Neuen, Brendon L., Olanrewaju, Timothy O., Vela Parada, Xavier Fernanco, Pecoits-Filho, Roberto, Petrova, Anna, Prasad, Bhanu, Radix, Lisa, Raina, Rupesh, Ullur, Avinash Rao, Rosner, Mitchell H., Sakajiki, Aminu Muhammad, See, Emily, Seshan, Surya V., Teitelbaum, Isaac, Thomas, Ian, Tiv, Sophanny, Trask, Michele, Vachharajani, Tushar J., Viecelli, Andrea, Wainstein, Marina, Walsh, Michael, Wyatt, Christina, Yeates, Karen, Yeung, Emily K., Young-Peart, Sandrica, and Zaidi, Deenaz
- Abstract
The International Society of Nephrology Global Kidney Health Atlas charts the availability and capacity of kidney care globally. In the North America and the Caribbean region, the Atlas can identify opportunities for kidney care improvement, particularly in Caribbean countries where structures for systematic data collection are lacking. In this third iteration, respondents from 12 of 18 countries from the region reported a 2-fold higher than global median prevalence of dialysis and transplantation, and a 3-fold higher than global median prevalence of dialysis centers. The peritoneal dialysis prevalence was lower than the global median, and transplantation data were missing from 6 of the 10 Caribbean countries. Government-funded payments predominated for dialysis modalities, with greater heterogeneity in transplantation payor mix. Services for chronic kidney disease, such as monitoring of anemia and blood pressure, and diagnostic capability relying on serum creatinine and urinalyses were universally available. Notable exceptions in Caribbean countries included non-calcium-based phosphate binders and kidney biopsy services. Personnel shortages were reported across the region. Kidney failure was identified as a governmental priority more commonly than was chronic kidney disease or acute kidney injury. In this generally affluent region, patients have better access to kidney replacement therapy and chronic kidney disease–related services than in much of the world. Yet clear heterogeneity exists, especially among the Caribbean countries struggling with dialysis and personnel capacity. Important steps to improve kidney care in the region include increased emphasis on preventive care, a focus on home-based modalities and transplantation, and solutions to train and retain specialized allied health professionals.
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- 2024
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92. The Pathophysiology of Inherited Renal Cystic Diseases.
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Satariano, Matthew, Ghose, Shaarav, and Raina, Rupesh
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CYSTIC kidney disease ,AUTOSOMAL recessive polycystic kidney ,POLYCYSTIC kidney disease ,KIDNEY diseases - Abstract
Renal cystic diseases (RCDs) can arise from utero to early adulthood and present with a variety of symptoms including renal, hepatic, and cardiovascular manifestations. It is well known that common RCDs such as autosomal polycystic kidney disease and autosomal recessive kidney disease are linked to genes such as PKD1 and PKHD1, respectively. However, it is important to investigate the genetic pathophysiology of how these gene mutations lead to clinical symptoms and include some of the less-studied RCDs, such as autosomal dominant tubulointerstitial kidney disease, multicystic dysplastic kidney, Zellweger syndrome, calyceal diverticula, and more. We plan to take a thorough look into the genetic involvement and clinical sequalae of a number of RCDs with the goal of helping to guide diagnosis, counseling, and treatment. [ABSTRACT FROM AUTHOR]
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- 2024
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93. Caffeine and kidney function at two years in former extremely low gestational age neonates.
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Harer, Matthew W., Griffin, Russell, Askenazi, David J., Fuloria, Mamta, Guillet, Ronnie, Hanna, Mina, Schuh, Meredith P., Slagle, Cara, Woroniecki, Robert, Neonatal Kidney Collaborative Research Committee, DeFreitas, Marissa, Gist, Katja M., Menon, Shina, Nesargi, Saudamini, Raina, Rupesh, Sanderson, Keia, Segar, Jeffrey L., Selewski, David T., South, Andrew M., and Steflik, Heidi J.
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- 2024
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94. Use of furosemide in preterm neonates with acute kidney injury is associated with increased mortality: results from the TINKER registry
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Raina, Rupesh, primary, Sethi, Sidharth Kumar, additional, Agrawal, Gopal, additional, Wazir, Sanjay, additional, Bajaj, Naveen, additional, Gupta, Naveen Parkash, additional, Tibrewal, Abhishek, additional, Vadhera, Ananya, additional, Mirgunde, Shishir, additional, Balachandran, Binesh, additional, Sahoo, Jagdish, additional, Afzal, Kamran, additional, Shrivastava, Anubha, additional, Bagla, Jyoti, additional, Krishnegowda, Sushma, additional, Konapur, Ananth, additional, Soni, Kritika, additional, Alhasan, Khalid, additional, McCulloch, Mignon, additional, and Bunchman, Timothy, additional
- Published
- 2023
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95. Atypical Hemolytic-Uremic Syndrome: Genetic Basis, Clinical Manifestations, and a Multidisciplinary Approach to Management
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Yerigeri, Keval, primary, Kadatane, Saurav, additional, Mongan, Kai, additional, Boyer, Olivia, additional, Burke, Linda LG, additional, Sethi, Sidharth Kumar, additional, Licht, Christoph, additional, and Raina, Rupesh, additional
- Published
- 2023
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96. A rare complication of pauci-immune crescentic glomerulonephritis in a child: Questions
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Sethi, Sidharth Kumar, Rana, Abhyuday, Bansal, Shyam Bihari, Rana, Alka, Yadav, Dinesh Kumar, Soni, Kritika, Dragon-Durey, Marie-Agnès, Raina, Rupesh, and Kher, Vijay
- Published
- 2021
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97. Pediatric intradialytic hypotension: recommendations from the Pediatric Continuous Renal Replacement Therapy (PCRRT) Workgroup
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Raina, Rupesh, Lam, Stephanie, Raheja, Hershita, Krishnappa, Vinod, Hothi, Daljit, Davenport, Andrew, and Chand, Deepa
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Pediatric research ,Hemodialysis -- Psychological aspects ,Renal replacement therapy -- Usage ,Hypotension -- Research ,Health - Abstract
Intradialytic hypotension (IDH) is a common adverse event resulting in premature interruption of hemodialysis, and consequently, inadequate fluid and solute removal. IDH occurs in response to the reduction in blood volume during ultrafiltration and subsequent poor compensatory mechanisms due to abnormal cardiac function or autonomic or baroreceptor failure. Pediatric patients are inherently at risk for IDH due to the added difficulty of determining and attaining an accurate dry weight. While frequent blood pressure monitoring, dialysate sodium profiling, ultrafiltration-guided blood volume monitoring, dialysate cooling, hemodiafiltration, and intradialytic mannitol and midodrine have been used to prevent IDH, they have not been extensively studied in pediatric population. Lack of large-scale studies on IDH in children makes it difficult to develop evidence-based management guidelines. Here, we aim to review IDH preventative strategies in the pediatric population and outlay recommendations from the Pediatric Continuous Renal Replacement Therapy (PCRRT) Workgroup. Without strong evidence in the literature, our recommendations from the expert panel reflect expert opinion and serve as a valuable guide., Author(s): Rupesh Raina [sup.1] [sup.2] , Stephanie Lam [sup.3] , Hershita Raheja [sup.4] , Vinod Krishnappa [sup.2] [sup.5] , Daljit Hothi [sup.6] , Andrew Davenport [sup.7] , Deepa Chand [sup.8] [...]
- Published
- 2019
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98. Predictors of patency for arteriovenous fistulae and grafts in pediatric hemodialysis patients
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Onder, Ali Mirza, Flynn, Joseph T., Billings, Anthony A., Deng, Fang, DeFreitas, Marissa, Katsoufis, Chryso, Grinsell, Matthew M., Patterson, Larry T., Jetton, Jennifer, Fathallah-Shaykh, Sahar, Ranch, Daniel, Aviles, Diego, Copelovitch, Lawrence, Ellis, Eileen, Chanda, Vimal, Elmaghrabi, Ayah, Lin, Jen-Jar, Butani, Lavjay, Haddad, Maha, Couloures, Olivera Marsenic, Brakeman, Paul, Quigley, Raymond, Stella Shin, H., Garro, Rouba, Liu, Hui, Rahimikollu, Javad, Raina, Rupesh, Langman, Craig B., Wood, Ellen G., and on behalf of the Midwest Pediatric Nephrology Consortium
- Published
- 2019
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- View/download PDF
99. Optimizing the AKI definition during first postnatal week using Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates (AWAKEN) cohort
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Askenazi, David, Abitbol, Carolyn, Boohaker, Louis, Griffin, Russell, Raina, Rupesh, Dower, Joshua, Davis, T. Keefe, Ray, Patricio E., Perazzo, Sofia, DeFreitas, Marissa, Milner, Lawrence, Ambalavanan, Namasivayam, Cole, F. Sessions, Rademacher, Erin, Zappitelli, Michael, Mhanna, Maroun, and for the Neonatal Kidney Collaborative
- Published
- 2019
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100. Self-Management and Health Care Transition Among Adolescents and Young Adults With Chronic Kidney Disease: Medical and Psychosocial Considerations
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Díaz-González de Ferris, Maria E., Del Villar-Vilchis, Marta, Guerrero, Ricardo, Barajas-Valencia, Victor M., Vander-Schaaf, Emily B., de Pomposo, Alexandre, Medeiros, Mara, Rak, Eniko, Cantu-Quintanilla, Guillermo, Raina, Rupesh, and Alvarez-Elias, Ana C.
- Published
- 2017
- Full Text
- View/download PDF
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