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Renal replacement therapy in the management of intoxications in children: recommendations from the Pediatric Continuous Renal Replacement Therapy (PCRRT) workgroup
- Source :
- Pediatric Nephrology. November, 2019, Vol. 34 Issue 11, p2427, 22 p.
- Publication Year :
- 2019
-
Abstract
- Background Intentional or unintentional ingestions among children and adolescents are common. There are a number of ingestions amenable to renal replacement therapy (RRT). Methods We systematically searched PubMed/Medline, Embase, and Cochrane databases for literature regarding drugs/intoxicants and treatment with RRT in pediatric populations. Two experts from the PCRRT (Pediatric Continuous Renal Replacement Therapy) workgroup assessed titles, abstracts, and full-text articles for extraction of data. The data from the literature search was shared with the PCRRT workgroup and two expert toxicologists, and expert panel recommendations were developed. Results and Conclusions We have presented the recommendations concerning the use of RRTs for treatment of intoxications with toxic alcohols, lithium, vancomycin, theophylline, barbiturates, metformin, carbamazepine, methotrexate, phenytoin, acetaminophen, salicylates, valproic acid, and aminoglycosides.<br />Author(s): Rupesh Raina [sup.1] [sup.2] , Manpreet K Grewal [sup.2] , Martha Blackford [sup.3] , Jordan M. Symons [sup.4] , Michael J. G. Somers [sup.5] , Christoph Licht [sup.6] , [...]
Details
- Language :
- English
- ISSN :
- 0931041X
- Volume :
- 34
- Issue :
- 11
- Database :
- Gale General OneFile
- Journal :
- Pediatric Nephrology
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.602851655
- Full Text :
- https://doi.org/10.1007/s00467-019-04319-2