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The bisaminals obtained through the condensation of two linear tetraamines with glyoxal or pyruvic aldehyde were selectively alkylated with bromo- or α,ψ-dibromoalkanes in good yields at one of the secondary amino functions to give rise to N-monoalkylated tetraamines or linear octaamines. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)

The reductive amination of carbonyl compounds by the non-coordinated amino function of the fac-LM(CO)3 tridentate complexes of 1,4,7,10-tetraazadecane, 1,5,8,12-tetraazadodecane and 1,5,9,13-tetraazatridecane has been selectively achieved giving rise to ω-mono N-functionalized linear tetraamines.

The synthesis and the effect of phosphite–phosphonate ligands in rhodium-catalyzed hydroformylation of styrene are described. Activity and selectivity of the catalyst are improved, at low temperature, by increasing bulkiness of both phosphite and phosphonate moieties.

International audience; Several phosphonates with two fatty chains and different polar heads were synthesized and evaluated for their potential to transfer DNA into epithelial (COS-7) and hematopoietic (K562) cell lines, and compared to commercially available references. In both cases, ammonium-phosphonates were particularly efficient.

The fac-LCr(CO)3 tridentate complexes of 1,4,7,10-tetraazacyclododecane 1, 1,4,8,11-tetraazacyclotetradecane 2, 1,4,7,10-tetraazadecane 3 and 1,5,8,12-tetraazadodecane 4 have been selectively alkylated in high yield at the uncomplexed nitrogen atom, giving rise to mono N-functionalized tetraamines and bis-macrocyclic compounds.