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51. Impact of diabetes on clinical outcome among elderly patients with acute coronary syndrome treated with percutaneous coronary intervention: insights from the ELDERLY ACS 2 trial

Author

De Luca, Giuseppe, Verdoia, Monica, Savonitto, Stefano, Piatti, Luigi, Grosseto, Daniele, Morici, Nuccia, Bossi, Irene, Sganzerla, Paolo, Tortorella, Giovanni, Cacucci, Michele, Murena, Ernesto, Toso, Anna, Bongioanni, Sergio, Ravera, Amelia, Corrada, Elena, Mariani, Matteo, Di Ascenzo, Leonardo, Petronio, Anna S., Cavallini, Claudio, Vitrella, Giancarlo, Antonicelli, Roberto, Rogacka, Renata, and De Servi, Stefano

Published
2020
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53. Reply to SGLT-2 inhibitors: Post-infarction interventional effects

Author

Paolisso, Pasquale, Bergamaschi, Luca, Gragnano, Felice, Gallinoro, Emanuele, Cesaro, Arturo, Sardu, Celestino, Mileva, Niya, Foà, Alberto, Armillotta, Matteo, Sansonetti, Angelo, Amicone, Sara, Impellizzeri, Andrea, Esposito, Giuseppe, Morici, Nuccia, Andrea, Oreglia Jacopo, Casella, Gianni, Mauro, Ciro, Vassilev, Dobrin, Galie, Nazzareno, Santulli, Gaetano, Marfella, Raffaele, Calabro', Paolo, Barbato, Emanuele, Pizzi, Carmine, Paolisso P., Bergamaschi Luca., Gragnano F., Gallinoro E., Cesaro A., Sardu C., Mileva N., Foa A., Armillotta Matteo, Sansonetti A., Amicone S., Impellizzeri A., Esposito Giuseppe., Morici N., Andrea O.J., Casella Gianni, Mauro Ciro, Vassilev D., Galie N., Santulli G., Marfella R., Calabro P., Barbato Emanuele., Pizzi Carmine, Paolisso, Pasquale, Bergamaschi, Luca, Gragnano, Felice, Gallinoro, Emanuele, Cesaro, Arturo, Sardu, Celestino, Mileva, Niya, Foà, Alberto, Armillotta, Matteo, Sansonetti, Angelo, Amicone, Sara, Impellizzeri, Andrea, Esposito, Giuseppe, Morici, Nuccia, Andrea, Oreglia Jacopo, Casella, Gianni, Mauro, Ciro, Vassilev, Dobrin, Galie, Nazzareno, Santulli, Gaetano, Marfella, Raffaele, Calabro', Paolo, Barbato, Emanuele, and Pizzi, Carmine

Subjects
Pharmacology, Acute myocardial infarction, PCI, prognosis
Published
2023

55. Impact of SGLT2-inhibitors on contrast-induced acute kidney injury in Diabetic patients with Acute Myocardial Infarction: Insight from SGLT2-I AMI PROTECT Registry

Author

Paolisso, Pasquale, primary, Bergamaschi, Luca, additional, Cesaro, Arturo, additional, Gallinoro, Emanuele, additional, Gragnano, Felice, additional, Sardu, Celestino, additional, Mileva, Niya, additional, Foà, Alberto, additional, Armillotta, Matteo, additional, Sansonetti, Angelo, additional, Amicone, Sara, additional, Impellizzeri, Andrea, additional, Belmonte, Marta, additional, Esposito, Giuseppe, additional, Morici, Nuccia, additional, Oreglia, Jacopo Andrea, additional, Casella, Gianni, additional, Mauro, Ciro, additional, Vassilev, Dobrin, additional, Galiè, Nazzareno, additional, Santulli, Gaetano, additional, Calabrò, Paolo, additional, Barbato, Emanuele, additional, Marfella, Raffaele, additional, and Pizzi, Carmine, additional

Published
2023
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57. Effect of a quality‐improvement intervention on end‐of‐life care in cardiac intensive care unit

Author

Sacco, Alice, primary, Tavecchia, Giovanni, additional, Ditali, Valentina, additional, Garatti, Laura, additional, Villanova, Luca, additional, Colombo, Claudia, additional, Viola, Giovanna, additional, Scavelli, Francesca, additional, Varrenti, Marisa, additional, Milani, Martina, additional, Morici, Nuccia, additional, Tavazzi, Guido, additional, Lissoni, Barbara, additional, Forni, Lorena, additional, Gorni, Giovanna, additional, Saporetti, Giorgia, additional, and Oliva, Fabrizio, additional

Published
2023
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62. Recombinant LCAT (Lecithin: Cholesterol Acyltransferase) Rescues Defective HDL (High-Density Lipoprotein)-Mediated Endothelial Protection in Acute Coronary Syndrome

Author

Ossoli, Alice, Simonelli, Sara, Varrenti, Marisa, Morici, Nuccia, Oliva, Fabrizio, Stucchi, Miriam, Gomaraschi, Monica, Strazzella, Arianna, Arnaboldi, Lorenzo, Thomas, Michael J., Sorci-Thomas, Mary G., Corsini, Alberto, Veglia, Fabrizio, Franceschini, Guido, Karathanasis, Sotirios K., and Calabresi, Laura

Published
2019
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64. Use of mechanical circulatory support in patients with non‐ischaemic cardiogenic shock

Author

Schrage, Benedikt, primary, Sundermeyer, Jonas, additional, Beer, Benedikt Norbert, additional, Bertoldi, Letizia, additional, Bernhardt, Alexander, additional, Blankenberg, Stefan, additional, Dauw, Jeroen, additional, Dindane, Zouhir, additional, Eckner, Dennis, additional, Eitel, Ingo, additional, Graf, Tobias, additional, Horn, Patrick, additional, Kirchhof, Paulus, additional, Kluge, Stefan, additional, Linke, Axel, additional, Landmesser, Ulf, additional, Luedike, Peter, additional, Lüsebrink, Enzo, additional, Mangner, Norman, additional, Maniuc, Octavian, additional, Winkler, Sven Möbius, additional, Nordbeck, Peter, additional, Orban, Martin, additional, Pappalardo, Federico, additional, Pauschinger, Matthias, additional, Pazdernik, Michal, additional, Proudfoot, Alastair, additional, Kelham, Matthew, additional, Rassaf, Tienush, additional, Reichenspurner, Hermann, additional, Scherer, Clemens, additional, Schulze, Paul Christian, additional, Schwinger, Robert H.G., additional, Skurk, Carsten, additional, Sramko, Marek, additional, Tavazzi, Guido, additional, Thiele, Holger, additional, Villanova, Luca, additional, Morici, Nuccia, additional, Wechsler, Antonia, additional, Westenfeld, Ralf, additional, Winzer, Ephraim, additional, and Westermann, Dirk, additional

Published
2023
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65. The Effect of Antithrombotic Treatment on Mortality in Patients with Acute Infection: A Meta-Analysis of Randomized Clinical Trials

Author

Gazzaniga, Gianluca, primary, Tavecchia, Giovanni Amedeo, additional, Bravi, Francesca, additional, Scavelli, Francesca, additional, Travi, Giovanna, additional, Campo, Gianluca, additional, Vandenbriele, Christophe, additional, Tritschler, Tobias, additional, Sterne, Jonathan, additional, Murthy, Srinivas, additional, and Morici, Nuccia, additional

Published
2023
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66. Reply to SGLT-2 inhibitors: Post-infarction interventional effects

Author

Paolisso, Pasquale, primary, Bergamaschi, Luca, additional, Gragnano, Felice, additional, Gallinoro, Emanuele, additional, Cesaro, Arturo, additional, Sardu, Celestino, additional, Mileva, Niya, additional, Foà, Alberto, additional, Armillotta, Matteo, additional, Sansonetti, Angelo, additional, Amicone, Sara, additional, Impellizzeri, Andrea, additional, Esposito, Giuseppe, additional, Morici, Nuccia, additional, Andrea, Oreglia Jacopo, additional, Casella, Gianni, additional, Mauro, Ciro, additional, Vassilev, Dobrin, additional, Galie, Nazzareno, additional, Santulli, Gaetano, additional, Marfella, Raffaele, additional, Calabrò, Paolo, additional, Barbato, Emanuele, additional, and Pizzi, Carmine, additional

Published
2023
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67. The Exercise and Heart Transplant (Enea) Trial – a Registry-Based Randomized Controlled Trial Evaluating the Safety and Efficacy of Cardiac Telerehabilitation after Heart Transplant

Author

Pedersini, Paolo, primary, Picciolini, Silvia, additional, Di Salvo, Francesca, additional, Toccafondi, Anastasia, additional, Novembre, Giulia, additional, Gualerzi, Alice, additional, Cusmano, Ignazio, additional, Garascia, Andrea, additional, Tavanelli, Monica, additional, Verde, Alessandro, additional, Masciocco, Gabriella, additional, Ricci, Cristian, additional, Mannini, Andrea, additional, Bedoni, Marzia, additional, and Morici, Nuccia, additional

Published
2023
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69. Management and Long-Term Prognosis of Spontaneous Coronary Artery Dissection

Author

Lettieri, Corrado, Zavalloni, Dennis, Rossini, Roberta, Morici, Nuccia, Ettori, Federica, Leonzi, Ornella, Latib, Azeem, Ferlini, Marco, Trabattoni, Daniela, Colombo, Paola, Galli, Mario, Tarantini, Giuseppe, Napodano, Massimo, Piccaluga, Emanuela, Passamonti, Enrico, Sganzerla, Paolo, Ielasi, Alfonso, Coccato, Micol, Martinoni, Alessandro, Musumeci, Giuseppe, Zanini, Roberto, and Castiglioni, Battistina

Published
2015
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74. 471 IMPACT OF COMPLETE REVASCULARIZATION ON DEVELOPMENT OF HEART FAILURE IN PATIENTS WITH ACUTE CORONARY SYNDROME AND MULTIVESSEL DISEASE

Author

Bruno, Francesco, primary, Marengo, Giorgio, additional, Filippo, Ovidio De, additional, Wanha, Wojciech, additional, Leonardi, Sergio, additional, Rubin, Sergio Raposeiras, additional, Fabris, Enrico, additional, Giannino, Giuseppe, additional, Truffa, Alessandra, additional, Gaibazzi, Nicola, additional, Ielasi, Alfonso, additional, Sardella, Gennaro, additional, Gallone, Guglielmo, additional, Cortese, Bernardo, additional, Montalto, Claudio, additional, Ugo, Fabrizio, additional, Barbieri, Lucia, additional, Morici, Nuccia, additional, Mancone, Massimo, additional, Campo, Gianluca, additional, Sinagra, Gianfranco, additional, D´ascenzo, Fabrizio, additional, and De Ferrari, Gaetano Maria, additional

Published
2022
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75. 1134 IN-HOSPITAL ARRHYTHMIC BURDEN REDUCTION IN DIABETIC PATIENTS WITH ACUTE MYOCARDIAL INFARCTION TREATED WITH SGLT2-INHIBITORS: INSIGHTS FROM THE SGLT2-I AMI PROTECT STUDY

Author

Cesaro, Arturo, primary, Gragnano, Felice, additional, Paolisso, Pasquale, additional, Bergamaschi, Luca, additional, Gallinoro, Emanuele, additional, Sardu, Celestino, additional, Mileva, Niya, additional, Foà, Alberto, additional, Armilotta, Matteo, additional, Sansonetti, Angelo, additional, Amicone, Sara, additional, Impellizzeri, Andrea, additional, Esposito, Giuseppe, additional, Morici, Nuccia, additional, Oreglia, Andrea Jacopo, additional, Casella, Gianni, additional, Mauro, Ciro, additional, Vassilev, Dobrin, additional, Galiè, Nazzareno, additional, Santulli, Gaetano, additional, Pizzi, Carmine, additional, Barbato, Emanuele, additional, Calabrò, Paolo, additional, and Marfella, Raffaele, additional

Published
2022
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76. 528 OUTCOMES IN DIABETIC PATIENTS WITH ACUTE MYOCARDIAL INFARCTION TREATED WITH SGLT2-I: THE SGLT2-I AMI PROTECT REGISTRY

Author

Paolisso, Pasquale, primary, Bergamaschi, Luca, additional, Gragnano, Felice, additional, Gallinoro, Emanuele, additional, Cesaro, Arturo, additional, Sardu, Celestino, additional, Mileva, Niya, additional, Foà, Alberto, additional, Armillotta, Matteo, additional, Sansonetti, Angelo, additional, Amicone, Sara, additional, Impellizzeri, Andrea, additional, Esposito, Giuseppe, additional, Morici, Nuccia, additional, Oreglia, Jacopo Andrea, additional, Casella, Gianni, additional, Mauro, Ciro, additional, Vassilev, Dobrin, additional, Galiè, Nazzareno, additional, Marfella, Raffaele, additional, Santulli, Gaetano, additional, Calabrò, Paolo, additional, Pizzi, Carmine, additional, and Barbato, Emanuele, additional

Published
2022
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77. SCAI stage reclassification at 24 h predicts outcome of cardiogenic shock: Insights from the Altshock-2 registry

Author

Morici, Nuccia, Frea, Simone, Bertaina, Maurizio, Sacco, Alice, Corrada, Elena, Dini, Carlotta Sorini, Briani, Martina, Tedeschi, Michele, Saia, Francesco, Colombo, Costanza, Rota, Matteo, Oliva, Fabrizio, Iannaccone, Mario, De Ferrari, Gaetano M., Sionis, Alessandro, Kapur, Navin K., Tavazzi, Guido, Pappalardo, Federico, and Universitat Autònoma de Barcelona

Subjects
Radiology, Nuclear Medicine and imaging, Heart failure, General Medicine, SCAI stages, Cardiology and Cardiovascular Medicine, Cardiogenic shock
Abstract

Cardiogenic shock (CS) includes several phenotypes with heterogenous hemodynamic features. Timely prognostication is warranted to identify patients requiring treatment escalation. We explored the association of the updated Society for Cardiovascular Angiography and Interventions (SCAI) stages classification with in-hospital mortality using a prospective national registry.Between March 2020 and February 2022 the Altshock-2 Registry has included 237 patients with CS of all etiologies at 11 Italian Centers. Patients were classified according to their admission SCAI stage (assigned prospectively and independently updated according to the recently released version). In-hospital mortality was evaluated for association with both admission and 24-h SCAI stages.The overall in-hospital mortality was 38%. Of the 237 patients included and staged according to the updated SCAI classification, 20 (8%) had SCAI shock stage B, 131 (55%) SCAI stage C, 61 (26%) SCAI stage D and 25 (11%) SCAI stage E. In-hospital mortality stratified according to the SCAI classification at 24 h was 18% for patients in SCAI stage B, 27% for SCAI stage C, 63% for SCAI stage D and 100% for SCAI stage E. Both the revised SCAI stages on admission and at 24 h were associated with in-hospital mortality, but the classification potential slightly increased at 24-h. After adjusting for age, sex, lactate level, eGFR, CVP, inotropic score and mechanical circulatory support [MCS], SCAI classification at 24 h was an independent predictor of in-hospital mortality.In the Altshock-2 registry the utility of SCAI shock stages to identify risk of in-hospital mortality increased at 24 h after admission. Escalation of treatment (either pharmacological or with MCS) should be tailored to achieve prompt clinical improvement within the first 24 h after admission. Registration: http://www.gov; Unique identifier: NCT04295252.

Published
2022

80. Acute Kidney Injury After Transcatheter Aortic Valve Replacement Mediates the Effect of Chronic Kidney Disease

Author

Crimi, Gabriele, primary, De Marzo, Vincenzo, additional, De Marco, Federico, additional, Conrotto, Federico, additional, Oreglia, Jacopo, additional, D'Ascenzo, Fabrizio, additional, Testa, Luca, additional, Gorla, Riccardo, additional, Esposito, Giuseppe, additional, Sorrentino, Sabato, additional, Spaccarotella, Carmen, additional, Soriano, Francesco, additional, Bruno, Francesco, additional, Vercellino, Matteo, additional, Balbi, Manrico, additional, Morici, Nuccia, additional, Indolfi, Ciro, additional, De Ferrari, Gaetano Maria, additional, Bedogni, Francesco, additional, and Porto, Italo, additional

Published
2022
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82. In-hospital arrhythmic burden reduction in diabetic patients with acute myocardial infarction treated with SGLT2-inhibitors: Insights from the SGLT2-I AMI PROTECT study

Author

Cesaro, Arturo, primary, Gragnano, Felice, additional, Paolisso, Pasquale, additional, Bergamaschi, Luca, additional, Gallinoro, Emanuele, additional, Sardu, Celestino, additional, Mileva, Niya, additional, Foà, Alberto, additional, Armillotta, Matteo, additional, Sansonetti, Angelo, additional, Amicone, Sara, additional, Impellizzeri, Andrea, additional, Esposito, Giuseppe, additional, Morici, Nuccia, additional, Oreglia, Jacopo Andrea, additional, Casella, Gianni, additional, Mauro, Ciro, additional, Vassilev, Dobrin, additional, Galie, Nazzareno, additional, Santulli, Gaetano, additional, Pizzi, Carmine, additional, Barbato, Emanuele, additional, Calabrò, Paolo, additional, and Marfella, Raffaele, additional

Published
2022
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83. The impact of transcatheter edge‐to‐edge repair on right ventricle‐pulmonary artery coupling in patients with functional mitral regurgitation

Author

Tua, Lorenzo, primary, Mandurino‐Mirizzi, Alessandro, additional, Colombo, Claudia, additional, Morici, Nuccia, additional, Magrini, Giulia, additional, Nava, Stefano, additional, Frassica, Romina, additional, Montalto, Claudio, additional, Ferlini, Marco, additional, Sacco, Alice, additional, Musca, Francesco, additional, Moreo, Antonella, additional, Ghio, Stefano, additional, Oreglia, Jacopo, additional, Oltrona‐Visconti, Luigi, additional, Oliva, Fabrizio, additional, and Crimi, Gabriele, additional

Published
2022
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85. TCT-414 Impact of Transcatheter Edge-to-Edge Repair on Right Ventricle-Pulmonary Artery Coupling in Patients With Functional Mitral Regurgitation

Author

Tua, Lorenzo, primary, Mandurino, Alessandro, additional, Colombo, Claudia, additional, Morici, Nuccia, additional, Nava, Stefano, additional, Frassica, Romina, additional, Montalto, Claudio, additional, Sacco, Alice, additional, Ferlini, Marco, additional, Ghio, Stefano, additional, Moreo, Antonella, additional, and Musca, Francesco, additional

Published
2022
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87. [Substance abuse and cardiovascular risk: cocaine]

Author

Ciccirillo, Francesco, Abrignani, Maurizio Giuseppe, Grosseto, Daniele, Amico, Antonio Francesco, Cocozza, Sara, Gabriele, Michele, Morici, Nuccia, Santucci, Andrea, Boschini, Antonio, Giallauria, Francesco, Caldarola, Pasquale, Gulizia, Michele Massimo, Gabrielli, Domenico, Colivicchi, Furio, Ciccirillo, Francesco, Abrignani, Maurizio Giuseppe, Grosseto, Daniele, Amico, Antonio Francesco, Cocozza, Sara, Gabriele, Michele, Morici, Nuccia, Santucci, Andrea, Boschini, Antonio, Giallauria, Francesco, Caldarola, Pasquale, Gulizia, Michele Massimo, Gabrielli, Domenico, and Colivicchi, Furio

Subjects
Young Adult, Cocaine, Substance-Related Disorders, Risk Factor, Cardiovascular Disease, Cocaine-Related Disorder, Heart Disease Risk Factor, Human
Abstract

Cocaine abuse is widely increasing, especially in younger individuals. Cocaine is a major cause of chest pain and acute coronary syndrome and is the leading cause for drug abuse-related visits to emergency departments, most of which are due to cardiovascular complaints. Cocaine use, especially long-term, is associated with an increased risk of all-cause mortality, and with several significant, life-threatening cardiovascular diseases although the multifactorial underlying cellular and molecular pathophysiological mechanisms of acute and chronic cocaine cardiotoxicity are not well established due to limited studies. Current findings have important public health implications, reinforcing recommendations for substance use screening among young adults with heart diseases, and highlighting the need for education on its deleterious effects. Cocaine should be considered a cardiovascular risk factor, requiring attention to early detection of vascular disease in cocaine users.

Published
2022

89. Comparison of Reduced-Dose Prasugrel and Standard-Dose Clopidogrel in Elderly Patients With Acute Coronary Syndromes Undergoing Early Percutaneous Revascularization

Author

Savonitto, Stefano, Ferri, Luca A., Piatti, Luigi, Grosseto, Daniele, Piovaccari, Giancarlo, Morici, Nuccia, Bossi, Irene, Sganzerla, Paolo, Tortorella, Giovanni, Cacucci, Michele, Ferrario, Maurizio, Murena, Ernesto, Sibilio, Girolamo, Tondi, Stefano, Toso, Anna, Bongioanni, Sergio, Ravera, Amelia, Corrada, Elena, Mariani, Matteo, Di Ascenzo, Leonardo, Petronio, A. Sonia, Cavallini, Claudio, Vitrella, Giancarlo, Rogacka, Renata, Antonicelli, Roberto, Cesana, Bruno M., De Luca, Leonardo, Ottani, Filippo, De Luca, Giuseppe, Piscione, Federico, Moffa, Nadia, De Servi, Stefano, Bolognese, Leonardo, Bovenzi, Francesco, Steffenino, Giuseppe, Santilli, Ignazio, Bassanelli, Giorgio, Sacco, Alice, Canziani, Federico, Ferri, Marco, Lo Jacono, Emilia, Canosi, Umberto, Fornaro, Giuseppe, Leoncini, Mario, Rosa Conte, Maria, Farina, Rosario, Stefanin, Catia, Di Pede, Francesco, Chella, Piersilvio, Chiara Nardoni, M., Tamburrini, Paola, Trimarco, Bruno, Galasso, Gennaro, Elia, Raffaele, Bolognese, Leonardo, Grotti, Simone, Bovenzi, Francesco, Borrelli, Lucia, Tamburino, Corrado, Capranzano, Piera, Francaviglia, Bruno, Campana, Carlo, Bonatti, Roberto, Martinoni, Alessandro, Abate, Fabio, Coscarelli, Sebastian, Rubartelli, Paolo, Villani, Giovanni Q., and Rossini, Roberta

Published
2018
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91. Predictors of mortality in hospital survivors with type 2 diabetes mellitus and acute coronary syndromes

Author

Savonitto, Stefano, Morici, Nuccia, Nozza, Anna, Cosentino, Francesco, Perrone Filardi, Pasquale, Murena, Ernesto, Morocutti, Giorgio, Ferri, Marco, Cavallini, Claudio, Eijkemans, Marinus JC, Stähli, Barbara E, Schrieks, Ilse C, Toyama, Tadashi, Lambers Heerspink, HJ, Malmberg, Klas, Schwartz, Gregory G, Lincoff, A Michael, Ryden, Lars, Tardif, Jean Claude, and Grobbee, Diederick E

Published
2018
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93. Association of statin pretreatment with presentation characteristics, infarct size and outcome in older patients with acute coronary syndrome: the Elderly ACS-2 trial

Author

Toso, Anna, primary, Morici, Nuccia, additional, Leoncini, Mario, additional, Villani, Simona, additional, Ferri, Luca A, additional, Piatti, Luigi, additional, Grosseto, Daniele, additional, Bossi, Irene, additional, Sganzerla, Paolo, additional, Tortorella, Giovanni, additional, Cacucci, Michele, additional, Ferrario, Maurizio, additional, Tondi, Stefano, additional, Ravera, Amelia, additional, Bellandi, Francesco, additional, Cavallini, Claudio, additional, Antonicelli, Roberto, additional, De Servi, Stefano, additional, and Savonitto, Stefano, additional

Published
2022
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94. Prognostic implications of pulmonary artery catheter monitoring in patients with cardiogenic shock: A systematic review and meta-analysis of observational studies

Author

Bertaina, Maurizio, primary, Galluzzo, Alessandro, additional, Rossello, Xavier, additional, Sbarra, Pierluigi, additional, Petitti, Elisabetta, additional, Prever, Silvia Brach, additional, Boccuzzi, Giacomo, additional, D'Ascenzo, Fabrizio, additional, Frea, Simone, additional, Pidello, Stefano, additional, Morici, Nuccia, additional, Sacco, Alice, additional, Oliva, Fabrizio, additional, Valente, Serafina, additional, De Ferrari, Gaetano Maria, additional, Ugo, Fabrizio, additional, Rametta, Francesco, additional, Attisani, Matteo, additional, Zanini, Paola, additional, Noussan, Patrizia, additional, and Iannaccone, Mario, additional

Published
2022
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97. Corrigendum to ‘Forecasting the Risk of Heart Failure Hospitalization After Acute Coronary Syndromes: the CORALYS HF Score’ [American Journal of Cardiology 206 (2023) 320-329]

Author

D'Ascenzo, Fabrizio, Fabris, Enrico, Gregorio, Caterina, Mittone, Gianluca, De Filippo, Ovidio, Wańha, Wojciech, Leonardi, Sergio, Roubin, Sergio Raposeiras, Chinaglia, Alessandra, Truffa, Alessandra, Huczek, Zenon, Gaibazzi, Nicola, Ielasi, Alfonso, Cortese, Bernardo, Borin, Andrea, Pagliaro, Beniamino, Núñez-Gil, Iván J, Ugo, Fabrizio, Marengo, Giorgio, Barbieri, Lucia, Marchini, Federico, Desperak, Piotr, Melendo-Viu, María, Montalto, Claudio, Bianco, Matteo, Bruno, Francesco, Mancone, Massimo, Ferrandez-Escarabajal, Marcos, Morici, Nuccia, Scaglione, Marco, Tuttolomondo, Domenico, Gąsior, Mariusz, Mazurek, Maciej, Gallone, Guglielmo, Campo, Gianluca, Wojakowski, Wojciech, Assi, Emad Abu, Stefanini, Giulio, Sinagra, Gianfranco, and Ferrari, Gaetano Mariade

Published
2024
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98. Cardiovascular injuries and SARS-COV-2 infection: focus on elderly people

Author

Colombo, Claudia, Garatti, Laura, Ferrante, Giulia, Casadei, Francesca, Montalto, Claudio, Crimi, Gabriele, Cogliati, Chiara, Ammirati, Enrico, Savonitto, Stefano, and Morici, Nuccia

Subjects
Research Article
Abstract

The novel coronavirus disease (COVID-19) has hit the healthcare system worldwide. The risk of severe infection and mortality increases with advancing age, especially in subjects with comorbidities such as cardiovascular disease, hypertension, diabetes, obesity and cancer. Moreover, cardiovascular complications such as myocardial injury, heart failure and thromboembolism are frequently observed in COVID-19 cases, and several biomarkers (troponin, NTproBNP and D-Dimer) have been identified as prognostic indicators of disease severity and worst outcome. Currently, there is no specific therapy against SARS-CoV-2, although many medications are under investigation. The aim of this review will be to explore the intertwined relationship between COVID-19 disease and the cardiovascular system, focusing on elderly population. The available supportive treatments along with the related concerns in elderly patients, due to their comorbidities and polypharmacotherapy, will be explored.

Published
2021

99. ESC guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic: part 1—epidemiology, pathophysiology, and diagnosis

Author

Baigent, Colin, Windecker, Stephan, Andreini, Daniele, Arbelo, Elena, Barbato, Emanuele, Bartorelli, Antonio, Baumbach, Andreas, Behr, Elijah, Berti, Sergio, Bueno, Héctor, Capodanno, Davide, Cappato, Riccardo, Chieffo, Alaide, Collet, Jean-Philippe, Cuisset, Thomas, de Simone, Giovanni, Delgado, Victoria, Dendale, Paul, Dudek, Dariusz, Edvardsen, Thor, Elvan, Arif, González-Juanatey, José, Gori, Mauro, Grobbee, Diederick, Guzik, Tomasz, Halvorsen, Sigrun, Haude, Michael, Heidbuchel, Hein, Hindricks, Gerhard, Ibanez, Borja, Karam, Nicole, Katus, Hugo, Klok, Fredrikus, Konstantinides, Stavros, Landmesser, Ulf, Leclercq, Christophe, Leonardi, Sergio, Lettino, Maddalena, Marenzi, Giancarlo, Mauri, Josepa, Metra, Marco, Morici, Nuccia, Mueller, Christian, Petronio, Anna Sonia, Polovina, Marija, Potpara, Tatjana, Praz, Fabien, Prendergast, Bernard, Prescott, Eva, Price, Susanna, Pruszczyk, Piotr, Rodríguez-Leor, Oriol, Roffi, Marco, Romaguera, Rafael, Rosenkranz, Stephan, Sarkozy, Andrea, Scherrenberg, Martijn, Seferovic, Petar, Senni, Michele, Spera, Francesco, Stefanini, Giulio, Thiele, Holger, Tomasoni, Daniela, Torracca, Lucia, Touyz, Rhian, Wilde, Arthur, Williams, Bryan, Bern University Hospital [Berne] (Inselspital), Centro Cardiologico Monzino [Milano], Dpt di Scienze Cliniche e di Comunità [Milano] (DISCCO), Università degli Studi di Milano = University of Milan (UNIMI)-Università degli Studi di Milano = University of Milan (UNIMI)-Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), 'Federico II' University of Naples Medical School, St George's, University of London, Fondazione Toscana Gabriele Monasterio, Hospital Universitario 12 de Octubre [Madrid], Centro Nacional de Investigaciones Cardiovasculares Carlos III [Madrid, Spain] (CNIC), Instituto de Salud Carlos III [Madrid] (ISC), University of Catania [Italy], IRCCS San Raffaele Scientific Institute [Milan, Italie], Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition [CHU Pitié Salpêtrière] (IHU ICAN), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Hôpital de la Timone [CHU - APHM] (TIMONE), Leiden University Medical Center (LUMC), Universiteit Leiden, Hasselt University (UHasselt), Jessa Ziekenhuis [Hasselt], Uniwersytet Jagielloński w Krakowie = Jagiellonian University (UJ), Oslo University Hospital [Oslo], Paris-Centre de Recherche Cardiovasculaire (PARCC (UMR_S 970/ U970)), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), CHU Pontchaillou [Rennes], Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), University College of London [London] (UCL), Università degli Studi di Milano [Milano] (UNIMI)-Università degli Studi di Milano [Milano] (UNIMI)-Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases [IHU ICAN], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPC), Université de Rennes 1 (UR1), and Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)

Subjects
Myocarditis, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, [SDV]Life Sciences [q-bio], Pulmonary embolism, ACE2, COVID-19, Heart failure, Thrombosis, Acute coronary syndromes, Arrhythmias, Cardiogenic shock, Biomarkers, Venous thromboembolism
Abstract

International audience; Aims - Since its emergence in early 2020, the novel severe acute respiratory syndrome coronavirus 2 causing coronavirus disease 2019 (COVID-19) has reached pandemic levels, and there have been repeated outbreaks across the globe. The aim of this two-part series is to provide practical knowledge and guidance to aid clinicians in the diagnosis and management of cardiovascular disease (CVD) in association with COVID-19. Methods and results - A narrative literature review of the available evidence has been performed, and the resulting information has been organized into two parts. The first, reported here, focuses on the epidemiology, pathophysiology, and diagnosis of cardiovascular (CV) conditions that may be manifest in patients with COVID-19. The second part, which will follow in a later edition of the journal, addresses the topics of care pathways, treatment, and follow-up of CV conditions in patients with COVID-19. Conclusion - This comprehensive review is not a formal guideline but rather a document that provides a summary of current knowledge and guidance to practicing clinicians managing patients with CVD and COVID-19. The recommendations are mainly the result of observations and personal experience from healthcare providers. Therefore, the information provided here may be subject to change with increasing knowledge, evidence from prospective studies, and changes in the pandemic. Likewise, the guidance provided in the document should not interfere with recommendations provided by local and national healthcare authorities.

Published
2022

100. European Society of Cardiology guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic: part 1-epidemiology, pathophysiology, and diagnosis The Task Force for the management of COVID-19 of the European Society of Cardiology

Author

Baigent, Colin, Windecker, Stephan, Andreini, Daniele, Arbelo, Elena, Barbato, Emanuele, Bartorelli, Antonio L., Baumbach, Andreas, Behr, Elijah R., Berti, Sergio, Bueno, Hector, Capodanno, Davide, Cappato, Riccardo, Chieffo, Alaide, Collet, Jean-Philippe, Cuisset, Thomas, de Simone, Giovanni, Delgado, Victoria, Dendale, Paul, Dudek, Dariusz, Edvardsen, Thor, Elvan, Arif, Gonzalez-Juanatey, Jose R., Gori, Mauro, Grobbee, Diederick, Guzik, Tomasz J., Halvorsen, Sigrun, Haude, Michael, Heidbuchel, Hein, Hindricks, Gerhard, Ibanez, Borja, Karam, Nicole, Katus, Hugo, Klok, Fredrikus A., Konstantinides, Stavros, V, Landmesser, Ulf, Leclercq, Christophe, Leonardi, Sergio, Lettino, Maddalena, Marenzi, Giancarlo, Mauri, Josepa, Metra, Marco, Morici, Nuccia, Mueller, Christian, Petronio, Anna Sonia, Polovina, Marija M., Potpara, Tatjana, Praz, Fabien, Prendergast, Bernard, Prescott, Eva, Price, Susanna, Pruszczyk, Piotr, Rodriguez-Leor, Oriol, Roffi, Marco, Romaguera, Rafael, Rosenkranz, Stephan, Sarkozy, Andrea, Scherrenberg, Martijn, Seferovic, Petar, Senni, Michele, Spera, Francesco R., Stefanini, Giulio, Thiele, Holger, Tomasoni, Daniela, Torracca, Luccia, Touyz, Rhian M., Wilde, Arthur A., Williams, Bryan, Baigent, Colin, Windecker, Stephan, Andreini, Daniele, Arbelo, Elena, Barbato, Emanuele, Bartorelli, Antonio L., Baumbach, Andreas, Behr, Elijah R., Berti, Sergio, Bueno, Hector, Capodanno, Davide, Cappato, Riccardo, Chieffo, Alaide, Collet, Jean-Philippe, Cuisset, Thomas, de Simone, Giovanni, Delgado, Victoria, Dendale, Paul, Dudek, Dariusz, Edvardsen, Thor, Elvan, Arif, Gonzalez-Juanatey, Jose R., Gori, Mauro, Grobbee, Diederick, Guzik, Tomasz J., Halvorsen, Sigrun, Haude, Michael, Heidbuchel, Hein, Hindricks, Gerhard, Ibanez, Borja, Karam, Nicole, Katus, Hugo, Klok, Fredrikus A., Konstantinides, Stavros, V, Landmesser, Ulf, Leclercq, Christophe, Leonardi, Sergio, Lettino, Maddalena, Marenzi, Giancarlo, Mauri, Josepa, Metra, Marco, Morici, Nuccia, Mueller, Christian, Petronio, Anna Sonia, Polovina, Marija M., Potpara, Tatjana, Praz, Fabien, Prendergast, Bernard, Prescott, Eva, Price, Susanna, Pruszczyk, Piotr, Rodriguez-Leor, Oriol, Roffi, Marco, Romaguera, Rafael, Rosenkranz, Stephan, Sarkozy, Andrea, Scherrenberg, Martijn, Seferovic, Petar, Senni, Michele, Spera, Francesco R., Stefanini, Giulio, Thiele, Holger, Tomasoni, Daniela, Torracca, Luccia, Touyz, Rhian M., Wilde, Arthur A., and Williams, Bryan

Abstract

Aims Since its emergence in early 2020, the novel severe acute respiratory syndrome coronavirus 2 causing coronavirus disease 2019 (COVID-19) has reached pandemic levels, and there have been repeated outbreaks across the globe. The aim of this two-part series is to provide practical knowledge and guidance to aid clinicians in the diagnosis and management of cardiovascular disease (CVD) in association with COVID-19. Methods and results A narrative literature review of the available evidence has been performed, and the resulting information has been organized into two parts. The first, reported here, focuses on the epidemiology, pathophysiology, and diagnosis of cardiovascular (CV) conditions that may be manifest in patients with COVID-19. The second part, which will follow in a later edition of the journal, addresses the topics of care pathways, treatment, and follow-up of CV conditions in patients with COVID-19. Conclusion This comprehensive review is not a formal guideline but rather a document that provides a summary of current knowledge and guidance to practicing clinicians managing patients with CVD and COVID-19. The recommendations are mainly the result of observations and personal experience from healthcare providers. Therefore, the information provided here may be subject to change with increasing knowledge, evidence from prospective studies, and changes in the pandemic. Likewise, the guidance provided in the document should not interfere with recommendations provided by local and national healthcare authorities. [GRAPHICS] .

Published
2022

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