51. Increased mortality among people with anxiety disorders: total population study.
- Author
-
Meier SM, Mattheisen M, Mors O, Mortensen PB, Laursen TM, and Penninx BW
- Subjects
- Adult, Case-Control Studies, Cause of Death, Comorbidity, Denmark epidemiology, Female, Humans, Male, Middle Aged, Registries, Young Adult, Anxiety Disorders epidemiology, Anxiety Disorders mortality, Depression epidemiology, Depression mortality
- Abstract
Background: Anxiety disorders and depression are the most common mental disorders worldwide and have a striking impact on global disease burden. Although depression has consistently been found to increase mortality; the role of anxiety disorders in predicting mortality risk is unclear., Aims: To assess mortality risk in people with anxiety disorders., Method: We used nationwide Danish register data to conduct a prospective cohort study with over 30 million person-years of follow-up., Results: In total, 1066 (2.1%) people with anxiety disorders died during an average follow-up of 9.7 years. The risk of death by natural and unnatural causes was significantly higher among individuals with anxiety disorders (natural mortality rate ratio (MRR) = 1.39, 95% CI 1.28-1.51; unnatural MRR = 2.46, 95% CI 2.20-2.73) compared with the general population. Of those who died from unnatural causes, 16.5% had comorbid diagnoses of depression (MRR = 11.72, 95% CI 10.11-13.51)., Conclusions: Anxiety disorders significantly increased mortality risk. Comorbidity of anxiety disorders and depression played an important part in the increased mortality., Competing Interests: Declaration of interest None., (© The Royal College of Psychiatrists 2016.)
- Published
- 2016
- Full Text
- View/download PDF