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53. Lipid-Oriented Live-Cell Distinction of B and T Lymphocytes

Author

Young-Tae Chang, Stuart N. Berry, Jae Won Lee, Justin Kok Soon Tan, Yun-Kyu Choi, Kangkyun Baek, Solip Park, Jae-Seong Yang, Gun Tae Jung, Kwang Pyo Kim, Soohyun Park, H. W. Lee, Haw-Young Kwon, Sangho Kim, Ki Hean Kim, Raj Kumar Das, Kyeng Min Park, Kimoon Kim, Sun Hyeok Lee, Nam-Young Kang, National Research Foundation of Korea, Government of South Korea, Institute for Basic Science (South Korea), Pohang University of Science and Technology, and Ministry of Education (South Korea)

Subjects
Cell type, T-Lymphocytes, Cell, Bone Marrow Cells, 010402 general chemistry, 01 natural sciences, Biochemistry, Catalysis, Cell membrane, Mice, Colloid and Surface Chemistry, medicine, Animals, Progenitor cell, Fluorescent Dyes, B-Lymphocytes, biology, Chemistry, Cell Membrane, Lymphocyte differentiation, Cell Differentiation, General Chemistry, Complex cell, Flow Cytometry, 0104 chemical sciences, Cell biology, Multicellular organism, medicine.anatomical_structure, Lipidomics, biology.protein, Antibody
Abstract

The identification of each cell type is essential for understanding multicellular communities. Antibodies set as biomarkers have been the main toolbox for cell-type recognition, and chemical probes are emerging surrogates. Herein we report the first small-molecule probe, CDgB, to discriminate B lymphocytes from T lymphocytes, which was previously impossible without the help of antibodies. Through the study of the origin of cell specificity, we discovered an unexpected novel mechanism of membrane-oriented live-cell distinction. B cells maintain higher flexibility in their cell membrane than T cells and accumulate the lipid-like probe CDgB more preferably. Because B and T cells share common ancestors, we tracked the cell membrane changes of the progenitor cells and disclosed the dynamic reorganization of the membrane properties over the lymphocyte differentiation progress. This study casts an orthogonal strategy for the small-molecule cell identifier and enriches the toolbox for live-cell distinction from complex cell communities., This research was supported by the Institute for Basic Science (IBS) (IBS-R007-A1), the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (no. 2020R1A2C2009776), the Ministry of Education (no. 2020R1A6A1A03047902), and the intramural fund of POSTECH (Pohang University of Science and Technology).

Published
2021
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58. Converging tetrahedron method calculations for the nondissipative parts of spectral functions

Author

Minsu Ghim, Cheol-Hwan Park, Seoul National University, Institute for Basic Science (South Korea), National Research Foundation of Korea, and Korea Institute of Science and Technology

Subjects
Condensed Matter - Materials Science, Materials Science (cond-mat.mtrl-sci), FOS: Physical sciences, Computational Physics (physics.comp-ph), Physics - Computational Physics
Abstract

Many physical quantities in solid-state physics are calculated from k-space summation. For spectral functions, the frequency-dependent factor can be decomposed into the energy-conserving δ-function part and the nondissipative principal value part. A very useful scheme for this k-space summation is the tetrahedron method. Tetrahedron methods have been widely used to calculate the summation of the energy-conserving δ-function part, such as the imaginary part of the dielectric function. On the other hand, the corresponding tetrahedron method for the nondissipative part, such as the real part of the dielectric function has not been used much. In this paper, we address the technical difficulties in the tetrahedron method for the nondissipative part and present an easy-to-implement stable method to overcome those difficulties. We demonstrate our method by calculating the static and dynamical spin Hall conductivity of platinum. Our method can be widely applied to calculate linear static or dynamical conductivity, self-energy of an electron, and electric polarizability, to name a few., This work was supported by the Creative-Pioneering Research Program through Seoul National University, Korean NRF No-2020R1A2C1014760, and the Institute for Basic Science (Grant IBSR009-D1). Computational resources were provided by KISTI Supercomputing Center (Grant No. KSC-2020-INO-0078).

Published
2022
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59. The Forced Response of the El Niño–Southern Oscillation–Indian Monsoon Teleconnection in Ensembles of Earth System Models

Author

Valerio Lucarini, Frank Lunkeit, Mátyás Herein, Tamas Bodai, Gábor Drótos, European Commission, German Research Foundation, National Research, Development and Innovation Office (Hungary), Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Govern de les Illes Balears, and Institute for Basic Science (South Korea)

Subjects
Monsoon of South Asia, Atmospheric Science, 010504 meteorology & atmospheric sciences, Oscillation, 01 natural sciences, 010305 fluids & plasmas, Earth system science, Max planck institute, El Niño Southern Oscillation, Indian summer monsoon, 13. Climate action, Climatology, 0103 physical sciences, Earth system model, ENSO, Geology, 0105 earth and related environmental sciences, Teleconnection
Abstract

We study the teleconnection between El Niño–Southern Oscillation (ENSO) and the Indian summer monsoon (IM) in large ensemble simulations, the Max Planck Institute Earth System Model (MPI-ESM), and the Community Earth System Model (CESM1). We characterize ENSO by the June–August Niño-3 box-average SST and the IM by the June–September average precipitation over India, and define their teleconnection in a changing climate as an ensemble-wise correlation. To test robustness, we also consider somewhat different variables that can characterize ENSO and the IM. We utilize ensembles converged to the system’s snapshot attractor for analyzing possible changes in the teleconnection. Our main finding is that the teleconnection strength is typically increasing on the long term in view of appropriately revised ensemble-wise indices. Indices involving a more western part of the Pacific reveal, furthermore, a short-term but rather strong increase in strength followed by some decrease at the turn of the century. Using the station-based Southern Oscillation index (SOI) as opposed to area-based indices leads to the identification of somewhat more erratic trends, but the turn-of-the-century “bump” is well detectable with it. All this is in contrast, if not in contradiction, to the discussion in the literature of a weakening teleconnection in the late twentieth century. We show here that this discrepancy can be due to any of three reasons: 1) ensemble-wise and temporal correlation coefficients used in the literature are different quantities; 2) the temporal moving correlation has a high statistical variability but possibly also persistence; or 3) MPI-ESM does not represent the Earth system faithfully., The simulations for the MPI-RCP8.5E were supported by the H2020 grant for the CRESCENDO project (Grant 641816). MH is thankful for the great support of the DFG Cluster of Excellence CliSAP. This research was supported by the National Research, Development and Innovation Office, NKFIH, under Grants PD124272, K125171, and FK124256. GD was supported by the Ministerio de Economía, Industria y Competitividad of the Spanish Government under Grant LAOP CTM2015-66407-P (AEI/FEDER, EU), and by the European Social Fund under CAIB grant PD/020/2018 “Margalida Comas”. TB, VL, and FL were supported by the H2020 grants for the CRESCENDO (Grant 641816) and Blue-Action (Grant 727852) projects. VL has been supported by the DFG Sfb/Transregio TRR181 project. TB was also supported by the Institute for Basic Science (IBS), under IBS-R028-D1.

Published
2020
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71. XPC–PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair

Author

Blessing, Charlotte, Apelt, Katja, Van Den Heuvel, Diana, González Leal, Claudia, Rother, Magdalena B, Van Der Woude, Melanie, González Prieto, Román, Luijsterburg, Martijn S., Universidad de Sevilla. Departamento de Biología Celular, Deutsche Forschungsgemeinschaft / German Research Foundation (DFG), Dutch Cancer Society, European Research Council (ERC), Netherlands Organization for Scientific Research, Institute of Basic Science (IBS). Korea, Natural Sciences and Engineering Research Council of Canada (NSERC), Israel Cancer Research Fund Research Career Development Award, Israel Cancer Association, Israel Science Foundation, Dutch Research Council, and National Cancer Institute (USA)

Abstract

Cells employ global genome nucleotide excision repair (GGR) to eliminate a broad spectrum of DNA lesions, including those induced by UV light. The lesion-recognition factor XPC initiates repair of helix-destabilizing DNA lesions, but binds poorly to lesions such as CPDs that do not destabilize DNA. How difficult-to-repair lesions are detected in chromatin is unknown. Here, we identify the poly-(ADP-ribose) polymerases PARP1 and PARP2 as constitutive interactors of XPC. Their interaction results in the XPC-stimulated synthesis of poly-(ADP-ribose) (PAR) by PARP1 at UV lesions, which in turn enables the recruitment and activation of the PAR-regulated chromatin remodeler ALC1. PARP2, on the other hand, modulates the retention of ALC1 at DNA damage sites. Notably, ALC1 mediates chromatin expansion at UV-induced DNA lesions, leading to the timely clearing of CPD lesions. Thus, we reveal how chromatin containing difficult-to-repair DNA lesions is primed for repair, providing insight into mechanisms of chromatin plasticity during GGR. German Research Foundation 213249687 - SFB 1064, 325871075 - SFB 1309 Dutch Cancer Society KWF-YIG 11367 European Research Council 310913 Netherlands Organization for Scientific Research 711.018.007 Institute of Basic Science IBS-R022-A1 Natural Sciences and Engineering Research Council of Canada RGPIN-2016-05868, RGPAS-492875-2016 Israel Cancer Research Fund Research Career Development Award 3013004741 Dutch Research Council ENW-M (OCENW.KLEIN.090), ALW.016.161.320, VI.C.182.052 National Cancer Insitute P01- CA092584 Israel Cancer Association 20210078 Israel Science Foundation 1710/17

Published
2022

72. Study of elastic and inelastic scattering of $^7$Be + $^{12}$C at 35 MeV

Author

K. Kundalia, D. Gupta, Sk M. Ali, Swapan K. Saha, O. Tengblad, J.D. Ovejas, A. Perea, I. Martel, J. Cederkall, J. Park, S. Szwec, A.M. Moro, European Commission, Indian Space Research Organisation, Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España), Swedish Research Council, Royal Physiographic Society of Lund, Institute for Basic Science (South Korea), Academy of Finland, Ministerio de Ciencia e Innovación (España), and Junta de Andalucía

Subjects
Nuclear Theory (nucl-th), Nuclear and High Energy Physics, Nuclear Theory, nucl-th, Nuclear Physics - Theory, FOS: Physical sciences, sironta, Nuclear Physics - Experiment, Nuclear Experiment (nucl-ex), ydinfysiikka, nucl-ex, Nuclear Experiment
Abstract

6 pags., 5 figs., 2 tabs., The elastic and inelastic scattering of Be from C have been measured at an incident energy of 35 MeV. The inelastic scattering leading to the 4.439 MeV excited state of C has been measured for the first time. The experimental data cover an angular range of θ = 15-120. Optical model analyses were carried out with Woods-Saxon and double-folding potential using the density dependent M3Y (DDM3Y) effective interaction. The microscopic analysis of the elastic data indicates breakup channel coupling effect. A coupled-channel analysis of the inelastic scattering, based on collective form factors, shows that mutual excitation of both Be and C is significantly smaller than the single excitation of C. The larger deformation length obtained from the DWBA analysis could be explained by including the excitation of Be in a coupled-channel analysis. The breakup cross section of Be is estimated to be less than 10% of the reaction cross section. The intrinsic deformation length obtained for the C (4.439 MeV) state is δ = 1.37 fm. The total reaction cross section deduced from the analysis agrees very well with Wong's calculations for similar weakly bound light nuclei on C target., D. Gupta acknowledges research funding from the European Union's Horizon 2020 research and innovation programme under grant agreement no. 654002 (ENSAR2) and ISRO, Government of India under grant no. ISRO/RES/2/378/15-16. O. Tengblad would like to acknowledge the support by the Spanish Funding Agency (AEI / FEDER, EU) under the project PID2019-104390GB-I00. I. Martel would like to acknowledge the support by the Ministry of Science, Innovation and Universities of Spain (Grant No. PGC2018-095640-B-I00). J. Cederkall acknowledges grants from the Swedish Research Council (VR) under contract numbers VR-2017-00637 and VR-2017-03986 as well as grants from the Royal Physiographical Society. J. Park would like to acknowledge the support by Institute for Basic Science (IBS-R031-D1). S. Szwec acknowledges support by the Academy of Finland (Grant No. 307685). A.M.M. is supported by the I+D+i project PID2020-114687GB-I00 funded by MCIN/AEI/10.13039/501100011033, by the grant Group FQM-160 and by project P20_01247, funded by the Consejería de Economía, Conocimiento, Empresas y Universidad, Junta de Andalucía (Spain) and by “ERDF A way of making Europe”.

Published
2022
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73. Reflectivity of Venus' dayside disk during the 2020 observation campaign: outcomes and future perspectives

Author

Lee, Yeon Joo, Muñoz, Antonio García, Yamazaki, Atsushi, Quémerais, Eric, Mottola, Stefano, Hellmich, Stephan, Granzer, Thomas, Bergond, Gilles, Roth, Martin, Gallego Cano, Eulalia, Chaufray, Jean-Yves, Robidel, Rozenn, Murakami, Go, Masunaga, Kei s, Kaplan, Murat, Erece, Orhan, Hueso, Ricardo, Kabáth, Petr, Špoková, Magdaléna, Sánchez-Lavega, Agustín, Kim, Myung-Jin, Mangano, Valeria, Jessup, Kandis-Lea, Widemann, Thomas, Sugiyama, Ko-ichiro, Watanabe, Shigeto, Yamada, Manabu, Satoh, Takehiko, Nakamura, Masato, Imai, Masataka se, Cabrera, Juan, DLR Institut für Planetenforschung, Deutsches Zentrum für Luft- und Raumfahrt [Berlin] (DLR), Pioneer Research Center for Climate and Earth Science (PRC), Institute of Basic Science (IBS), Astrophysique Interprétation Modélisation (AIM (UMR_7158 / UMR_E_9005 / UM_112)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institute of Space and Astronautical Science (ISAS), Japan Aerospace Exploration Agency [Sagamihara] (JAXA), Graduate School of Science [Tokyo], The University of Tokyo (UTokyo), HELIOS - LATMOS, Laboratoire Atmosphères, Milieux, Observations Spatiales (LATMOS), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Astrophysique [Versoix] (LASTRO), Ecole Polytechnique Fédérale de Lausanne (EPFL), Leibniz Institute for Astrophysics Potsdam (AIP), Centro Astronómico Hispano Alemán, Observatorio de Calar Alto (CAHA), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Instituto de Astrofísica de Andalucía (IAA), Akdeniz University, Departamento de Fisica Aplicada [Bilbao], Universidad del Pais Vasco / Euskal Herriko Unibertsitatea [Espagne] (UPV/EHU), Ondřejov Observatory of the Prague Astronomical Institute, Czech Academy of Sciences [Prague] (CAS), Department of Theoretical Physics and Astrophysics [Brno], Masaryk University [Brno] (MUNI), Korea Astronomy and Space Science Institute (KASI), Istituto di Astrofisica e Planetologia Spaziali - INAF (IAPS), Istituto Nazionale di Astrofisica (INAF), Southwest Research Institute [Boulder] (SwRI), Laboratoire d'études spatiales et d'instrumentation en astrophysique = Laboratory of Space Studies and Instrumentation in Astrophysics (LESIA), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Matsue National College of Technology, Hokkaido Information University, Planetary Exploration Research Center [Chiba] (PERC), Chiba Institute of Technology (CIT), Kyoto Sangyo University, Ministerio de Ciencia e Innovación (España), and European Commission

Subjects
atmospheric clouds, fourier-transform measurements, Earth and Planetary Astrophysics (astro-ph.EP), sulfur-dioxide, uv absorption, solar system astronomy, FOS: Physical sciences, absorption cross-sections, Venus, cloud-top, valence-shell, observational astronomy, s 2p, planetary science, photoabsorption, [SDU]Sciences of the Universe [physics], temperature-dependence, carbonyl sulfide, planetary atmospheres, Astrophysics - Earth and Planetary Astrophysics
Abstract

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited., We performed a unique Venus observation campaign to measure the disk brightness of Venus over a broad range of wavelengths in 2020 August and September. The primary goal of the campaign was to investigate the absorption properties of the unknown absorber in the clouds. The secondary goal was to extract a disk mean SO2 gas abundance, whose absorption spectral feature is entangled with that of the unknown absorber at ultraviolet wavelengths. A total of three spacecraft and six ground-based telescopes participated in this campaign, covering the 52–1700 nm wavelength range. After careful evaluation of the observational data, we focused on the data sets acquired by four facilities. We accomplished our primary goal by analyzing the reflectivity spectrum of the Venus disk over the 283–800 nm wavelengths. Considerable absorption is present in the 350–450 nm range, for which we retrieved the corresponding optical depth of the unknown absorber. The result shows the consistent wavelength dependence of the relative optical depth with that at low latitudes, during the Venus flyby by MESSENGER in 2007, which was expected because the overall disk reflectivity is dominated by low latitudes. Last, we summarize the experience that we obtained during this first campaign, which should enable us to accomplish our second goal in future campaigns. © 2022. The Author(s). Published by the American Astronomical Society., This research used data collected at the Centro Astronómico Hispano-Alemán (CAHA) at Calar Alto, operated jointly by Junta de Andalucía and Consejo Superior de Investigaciones Científicas (IAA-CSIC). This research has made use of the integral field spectroscopy data reduction tool p3d, which is provided by the Leibniz-Institut für Astrophysik Potsdam (AIP). Akatsuki/UVI data are publicly available at the JAXA archive website, DARTS (http://darts.isas.jaxa.jp/), and the NASA archive website, PDS (https://pds.nasa.gov/). UVI Level 3 products (l3bx) were used in this study (Murakami et al. 2018). This study used the TSIS-1 SIM data (Version 06, doi:10.25810/y9f8-ff85). M.K. and O.E. thank the TÜBİTAK National Observatory for partial support in using the T100 telescope, with project number 20CT100-1688. R.H. and A.S.L. have been supported by the Spanish project PID2019-109467GB-I00 (MINECO/FEDER, UE) and Grupos Gobierno Vasco IT-1366-19. P.K. and M.S. acknowledge support from grant LTT-20015., With funding from the Spanish government through the Severo Ochoa Centre of Excellence accreditation SEV-2017-0709.

Published
2022
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78. Obstructions for matroids of path-width at most k and graphs of linear rank-width at most k

Author

Kant��, Mamadou Moustapha, Kim, Eun Jung, Kwon, O-joung, Oum, Sang-il, Kim, Eunjung, Laboratoire d'Informatique, de Modélisation et d'Optimisation des Systèmes (LIMOS), Ecole Nationale Supérieure des Mines de St Etienne (ENSM ST-ETIENNE)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA)-Institut national polytechnique Clermont Auvergne (INP Clermont Auvergne), Université Clermont Auvergne (UCA)-Université Clermont Auvergne (UCA), Institut national polytechnique Clermont Auvergne (INP Clermont Auvergne), Université Clermont Auvergne (UCA), Laboratoire d'analyse et modélisation de systèmes pour l'aide à la décision (LAMSADE), Université Paris Dauphine-PSL, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Incheon National University, Department of Mathematical Sciences, KAIST, Korea Advanced Institute of Science and Technology (KAIST), Centre National de la Recherche Scientifique (CNRS), and Institute for Basic Science [Daejeon] (IBS)

Subjects
Mathematics of computing ��� Graph theory, path-width, linear rank-width, [INFO.INFO-DM]Computer Science [cs]/Discrete Mathematics [cs.DM], graph, [INFO] Computer Science [cs], Theoretical Computer Science, forbidden minor, Computational Theory and Mathematics, vertex-minor, FOS: Mathematics, Discrete Mathematics and Combinatorics, matroid, Mathematics - Combinatorics, [INFO]Computer Science [cs], Combinatorics (math.CO), pivot-minor, 05B35 (Primary), 05C75 (Secondary)
Abstract

Every minor-closed class of matroids of bounded branch-width can be characterized by a list of excluded minors, but unlike graphs, this list may need to be infinite in general. However, for each fixed finite field $\mathbb F$, the list needs to contain only finitely many $\mathbb F$-representable matroids, due to the well-quasi-ordering of $\mathbb F$-representable matroids of bounded branch-width under taking matroid minors [J. F. Geelen, A. M. H. Gerards, and G. Whittle (2002)]. But this proof is non-constructive and does not provide any algorithm for computing these $\mathbb F$-representable excluded minors in general. We consider the class of matroids of path-width at most $k$ for fixed $k$. We prove that for a finite field $\mathbb F$, every $\mathbb F$-representable excluded minor for the class of matroids of path-width at most $k$ has at most $2^{|\mathbb{F}|^{O(k^2)}}$ elements. We can therefore compute, for any integer $k$ and a fixed finite field $\mathbb F$, the set of $\mathbb F$-representable excluded minors for the class of matroids of path-width $k$, and this gives as a corollary a polynomial-time algorithm for checking whether the path-width of an $\mathbb F$-represented matroid is at most $k$. We also prove that every excluded pivot-minor for the class of graphs having linear rank-width at most $k$ has at most $2^{2^{O(k^2)}}$ vertices, which also results in a similar algorithmic consequence for linear rank-width of graphs., 19 pages; slightly revised

Published
2021
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79. Oxidation of Cymantrene-Tagged Tamoxifen Analogues: Effect of Diphenyl Functionalization on the Redox Mechanism

Author

Mu-Hyun Baik, Gérard Jaouen, William E. Geiger, Bimal Pudasaini, Kan Wu, Siden Top, Ji Young Park, University of Vermont [Burlington], Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS), Institut Parisien de Chimie Moléculaire (IPCM), Chimie Moléculaire de Paris Centre (FR 2769), Institut de Chimie du CNRS (INC)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Chimie du CNRS (INC)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), and Université Paris sciences et lettres (PSL)

Subjects
[CHIM.ORGA]Chemical Sciences/Organic chemistry, 010405 organic chemistry, Chemistry, Mechanism (biology), Organic Chemistry, 010402 general chemistry, Electrochemistry, 01 natural sciences, Combinatorial chemistry, Redox, 3. Good health, 0104 chemical sciences, Inorganic Chemistry, medicine, Surface modification, [CHIM.COOR]Chemical Sciences/Coordination chemistry, Physical and Theoretical Chemistry, ComputingMilieux_MISCELLANEOUS, [CHIM.CHEM]Chemical Sciences/Cheminformatics, Tamoxifen, medicine.drug
Abstract

The oxidations of 1,1′-di-p-anisolyl-2-cymantrenylbutene (3b) and 1,1′-di-p-hydroxyphenyl-2-cymantrenylbutene (3c) were investigated by electrochemical and spectroscopic experiments and by density ...

Published
2020
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80. Current-controlled magnetization using interfacial localizations in heterostructures

Author

Younghun Jo, Wilfrid Prellier, Prahallad Padhan, Eui-Young Choi, Byeong Kook Park, Seung-Young Park, Jiwon Seo, Seok Hyeon Hong, Byeong Cheol Min, Laboratoire de cristallographie et sciences des matériaux (CRISMAT), École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), Normandie Université (NU)-Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Institut de Chimie du CNRS (INC), Yonsei University, Korea Advanced Institute of Science and Technology (KAIST), Indian Institute of Technology Madras (IIT Madras), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), Normandie Université (NU)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche sur les Matériaux Avancés (IRMA), Normandie Université (NU)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Institut national des sciences appliquées Rouen Normandie (INSA Rouen Normandie), Institut National des Sciences Appliquées (INSA)-Normandie Université (NU)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Rouen Normandie (UNIROUEN), Institut National des Sciences Appliquées (INSA)-Normandie Université (NU)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS), Institute for Basic Science [Daejeon] (IBS), Indian Institute of Technology Delhi (IIT Delhi), and Korea Basic Science Institute (KBSI)

Subjects
Materials science, Magnetoresistance, Magnetism, General Physics and Astronomy, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Matrix (mathematics), Magnetization, Antiferromagnetism, [CHIM]Chemical Sciences, Interfacial localization, ComputingMilieux_MISCELLANEOUS, [PHYS]Physics [physics], Condensed matter physics, Heterojunction, Surfaces and Interfaces, General Chemistry, [CHIM.MATE]Chemical Sciences/Material chemistry, Interface, 021001 nanoscience & nanotechnology, Condensed Matter Physics, Magnetic inhomogeneity, 0104 chemical sciences, Surfaces, Coatings and Films, Magnetic field, Ferromagnetism, Condensed Matter::Strongly Correlated Electrons, Current-controlled magnetization, 0210 nano-technology
Abstract

International audience; A systematic study is conducted on an electrically controlled magnetization in tri-layers containing two layers of ferromagnetic (FM) SrRuO3, with antiferromagnetic (AFM) insulating manganites sandwiched in between. Magneto-resistance curves exhibit that a huge weak anti-localization or localization shapes around zero magnetic field and the localization shapes and coercive fields change simultaneously by currents. This results propose that interface-driven magnetic inhomogeneity such as the FM clusters embedded in the AFM matrix, and corresponding localizations play a role as a bridge between the current and magnetism. The results suggest that interfacial magnetism can cause new functions in a heterostructure, leading to an expansion of research subjects of current-controlled magnetism.

Published
2021
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81. New Multiscale Characterization Methodology for Effective Determination of Isolation–Structure–Function Relationship of Extracellular Vesicles

Author

Thanh Huyen Phan, Shiva Kamini Divakarla, Jia Hao Yeo, Qingyu Lei, Priyanka Tharkar, Taisa Nogueira Pansani, Kathryn G. Leslie, Maggie Tong, Victoria A. Coleman, Åsa Jämting, Mar-Dean Du Plessis, Elizabeth J. New, Bill Kalionis, Philip Demokritou, Hyun-Kyung Woo, Yoon-Kyoung Cho, Wojciech Chrzanowski, The University of Sydney, Universidade Estadual Paulista (UNESP), National Measurement Institute Australia, The University of Melbourne, Harvard T.H. Chan School of Public Health, Institute for Basic Science (IBS), and Ulsan National Institute of Science and Technology (UNIST)

Subjects
0301 basic medicine, Molecular composition, Histology, Computer science, Biomedical Engineering, Bioengineering, 02 engineering and technology, exosomes, Extracellular vesicles, single vesicle analysis, 03 medical and health sciences, ultracentrifugation, isolation methods, mesenchymal stromal/stem cell, nanodosimetry, Original Research, tangential flow filtration, Structure function, Bioengineering and Biotechnology, 021001 nanoscience & nanotechnology, Characterization (materials science), 030104 developmental biology, Biochemical engineering, 0210 nano-technology, extracellular vesicles, TP248.13-248.65, Biotechnology
Abstract

Made available in DSpace on 2022-04-29T08:29:58Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-06-07 Medical Advances Without Animals Trust Extracellular vesicles (EVs) have been lauded as next-generation medicines, but very few EV-based therapeutics have progressed to clinical use. Limited clinical translation is largely due to technical barriers that hamper our ability to mass produce EVs, i.e., to isolate, purify, and characterize them effectively. Technical limitations in comprehensive characterization of EVs lead to unpredicted biological effects of EVs. Here, using a range of optical and non-optical techniques, we showed that the differences in molecular composition of EVs isolated using two isolation methods correlated with the differences in their biological function. Our results demonstrated that the isolation method determines the composition of isolated EVs at single and sub-population levels. Besides the composition, we measured for the first time the dry mass and predicted sedimentation of EVs. These parameters were likely to contribute to the biological and functional effects of EVs on single cell and cell cultures. We anticipate that our new multiscale characterization approach, which goes beyond traditional experimental methodology, will support fundamental understanding of EVs as well as elucidate the functional effects of EVs in in vitro and in vivo studies. Our findings and methodology will be pivotal for developing optimal isolation methods and establishing EVs as mainstream therapeutics and diagnostics. This innovative approach is applicable to a wide range of sectors including biopharma and biotechnology as well as to regulatory agencies. Sydney School of Pharmacy Faculty of Medicine and Health Sydney Nano Institute The University of Sydney School of Chemistry The University of Sydney Department of Dental Materials and Prosthodontics Araraquara School of Dentistry UNESP-Universidade Estadual Paulista Nanometrology Section National Measurement Institute Australia School of Chemistry Faculty of Science Sydney Nano Institute The University of Sydney Maternal-Fetal Medicine Pregnancy Research Centre The Royal Women’s Hospital Department of Obstetrics and Gynaecology The University of Melbourne Department of Environmental Health Center for Nanotechnology and Nanotoxicology Harvard T.H. Chan School of Public Health Center for Soft and Living Matter Institute for Basic Science (IBS) Department of Biomedical Engineering Ulsan National Institute of Science and Technology (UNIST) Department of Dental Materials and Prosthodontics Araraquara School of Dentistry UNESP-Universidade Estadual Paulista

Published
2021
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84. Exceptional topology in ordinary soft matter

Author

Tsvi Tlusty, Tlusty, Tsvi, Center for Soft and Living Matter, Institute for Basic Science (IBS), and Pusan National University-Pusan National University

Subjects
[PHYS.PHYS.PHYS-FLU-DYN]Physics [physics]/Physics [physics]/Fluid Dynamics [physics.flu-dyn], Physics, Dirac (video compression format), Van Hove singularity, 02 engineering and technology, [PHYS.PHYS.PHYS-FLU-DYN] Physics [physics]/Physics [physics]/Fluid Dynamics [physics.flu-dyn], 021001 nanoscience & nanotechnology, Topology, 01 natural sciences, [PHYS.COND.CM-MS] Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci], [PHYS.COND.CM-SCM] Physics [physics]/Condensed Matter [cond-mat]/Soft Condensed Matter [cond-mat.soft], Flow (mathematics), Pairing, 0103 physical sciences, [PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci], Density of states, Gravitational singularity, Soft matter, 010306 general physics, 0210 nano-technology, [PHYS.COND.CM-SCM]Physics [physics]/Condensed Matter [cond-mat]/Soft Condensed Matter [cond-mat.soft], Topology (chemistry)
Abstract

International audience; Hydrodynamics is shown to induce non-Hermitian topological phenomena in ordinary, passive soft matter. This is demonstrated for the first time by subjecting a 2D elastic lattice to a low-Reynolds viscous flow. The interplay of hydrodynamics and elasticity splits Dirac cones into bulk Fermi arcs, pairing exceptional points with opposite half-integer topological charges. The bulk Fermi arc is a generic hallmark of the system exhibited in all lattice and flow symmetries. Analytic model and simulations explain how the emergent singularities shape the spectral bands and give rise to a web of van Hove singularity lines in the density of states. The present findings suggest that non-Hermitian physics can be explored in a broad class of ordinary soft matter, living and artificial alike, opening avenues for topology-based technology in this regime.

Published
2021

93. J eff = 3 2 metallic phase and unconventional superconductivity in GaTa 4 Se 8

Author

Jeong, Min Yong, Chang, Seo Hyoung, Lee, Hyeong Jun, Sim, Jae-Hoon, Lee, Kyeong Jun, Janod, Etienne, Cario, Laurent, Said, Ayman, Bi, Wenli, Werner, Philipp, Go, Ara, Kim, Jungho, Han, Myung Joon, Korea Advanced Institute of Science and Technology (KAIST), Chung-Ang University [Seoul], Institute for Basic Science [Daejeon] (IBS), Centre de Physique Théorique [Palaiseau] (CPHT), Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X), Institut des Matériaux Jean Rouxel (IMN), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Ecole Polytechnique de l'Université de Nantes (EPUN), Université de Nantes (UN)-Université de Nantes (UN), Argonne National Laboratory [Lemont] (ANL), University of Alabama at Birmingham [ Birmingham] (UAB), University of Fribourg, and Chonnam National University [Gwangju]

Subjects
[PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2021
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94. A pulsed high-voltage decelerator system to deliver low-energy antiprotons

Author

Valery Nesvizhevsky, K.-H. Yoo, J.-M. Reymond, P. Comini, B. Latacz, F. Nez, Alexei Voronin, Laurent Hilico, L. Dodd, P.-P. Crépin, M. Staszczak, B.H. Kim, Giuseppe Mornacchi, Jean-Philippe Karr, A. M. M. Leite, G. Janka, N. Garroum, S. Procureur, J.J. Choi, J.-Y. Roussé, J. Rzadkiewicz, Paul Indelicato, Hyo-Suk Lee, Pierre Cladé, M. Matusiak, B. Tuchming, T. Kosinski, P. Debu, Yasunori Yamazaki, Sun-Whe Kim, Eun-San Kim, A. Welker, Paolo Crivelli, M. Charlton, M. Chung, A. Husson, S. Wronka, S. Wolf, B. Vallage, O. D. Dalkarov, Y. Sacquin, C. Regenfus, S. Guellati-Khélifa, Naofumi Kuroda, R. Nishi, Serge Reynaud, Jaison Lee, S. Nourbaksh, Young Ju Ko, A. Douillet, Paul-Antoine Hervieux, D. Lunney, N. Paul, K. Lévêque, Giovanni Manfredi, P. Lotrus, P. Pérez, O. Rousselle, Bruno Mansoulie, E. Lim, Laszlo Liszkay, Svante Jonsell, K.H. Park, S. Niang, Ferdinand Schmidt-Kaler, André Rubbia, D. P. van der Werf, D. Won, B. Radics, Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Seoul National University [Seoul] (SNU), CERN [Genève], Swansea University, Ulsan National Institute of Science and Technology (UNIST), Laboratoire Kastler Brossel (LKB [Collège de France]), Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Collège de France (CdF (institution))-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Institute for Particle Physics and Astrophysics [ETH Zürich] (IPA), Department of Physics [ETH Zürich] (D-PHYS), Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich)- Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich), P. N. Lebedev Physical Institute of the Russian Academy of Sciences [Moscow] (LPI RAS), Russian Academy of Sciences [Moscow] (RAS), Université d'Évry-Val-d'Essonne (UEVE), Institut de Physique et Chimie des Matériaux de Strasbourg (IPCMS), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Matériaux et Nanosciences Grand-Est (MNGE), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Stockholm University, Korea University [Seoul], Institute for Basic Science [Daejeon] (IBS), National Centre for Nuclear Research [Otwock], Narodowe Centrum Badań Jądrowych (NCBJ), The University of Tokyo (UTokyo), Institut Laue-Langevin (ILL), Johannes Gutenberg - Universität Mainz = Johannes Gutenberg University (JGU), RIKEN - Institute of Physical and Chemical Research [Japon] (RIKEN), École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Collège de France (CdF (institution)), Université de Strasbourg (UNISTRA)-Matériaux et nanosciences d'Alsace (FMNGE), Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), ILL, and Johannes Gutenberg - Universität Mainz (JGU)

Subjects
Nuclear and High Energy Physics, Drift tube, General Relativity, Ion-optic simulations, CERN Lab, drift tube, Astrophysics::High Energy Astrophysical Phenomena, [PHYS.PHYS.PHYS-ACC-PH]Physics [physics]/Physics [physics]/Accelerator Physics [physics.acc-ph], Charged-particle optics, fabrication, 7. Clean energy, 01 natural sciences, anti-p: deceleration, law.invention, Nuclear physics, law, 0103 physical sciences, synchrotron, Physics::Atomic Physics, 010306 general physics, Antihydrogen, numerical calculations, Instrumentation, accelerator: design, Physics, antihydrogen, Large Hadron Collider, 010308 nuclear & particles physics, High voltage, Charged particle, Synchrotron, [PHYS.PHYS.PHYS-GEN-PH]Physics [physics]/Physics [physics]/General Physics [physics.gen-ph], Pulse (physics), beam optics, Antiproton, Physics::Accelerator Physics
Abstract

International audience; The GBAR (Gravitational Behavior of Antihydrogen at Rest) experiment at CERN requires efficient deceleration of 100 keV antiprotons provided by the new ELENA synchrotron ring to synthesize antihydrogen. This is accomplished using electrostatic deceleration optics and a drift tube that is designed to switch from -99 kV to ground when the antiproton bunch is inside – essentially a charged particle “elevator” – producing a 1 keV pulse. We describe the simulation, design, construction and successful testing of the decelerator device at -92 kV on-line with antiprotons from ELENA.

Published
2021
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95. Reactive astrocyte nomenclature, definitions, and future directions

Author

Arthur M. Butt, Elena Galea, Richard M. Ransohoff, Raymond A. Swanson, Eduardo R. Zimmer, Christopher M. Norris, Gilles Bonvento, Andras Lakatos, Philip G. Haydon, Wei Ting Chen, Christine R. Rose, Alexey Semyanov, Nicola J. Allen, Anna V. Molofsky, Javier Vitorica, Seiji Okada, Alfonso Araque, Antonia Gutierrez, Masamitsu Iino, Alberto Serrano-Pozo, Vittorio Gallo, C. Justin Lee, Magdalena Götz, Baljit S. Khakh, Christian Steinhäuser, Bart De Strooper, Stéphane H. R. Oliet, Andrea Volterra, Swetlana Sirko, Kira E. Poskanzer, Michael V. Sofroniew, Giorgio Carmignoto, Elly M. Hol, Frank W. Pfrieger, Beatriz G. Pérez-Nievas, Ksenia V. Kastanenka, Keith K. Murai, James P. O'Callaghan, Ina B. Wanner, David H. Rowitch, Pierre J. Magistretti, Cinthia Farina, Marcela Pekna, Albee Messing, Jia Qian Wu, Shane A. Liddelow, Dieter Henrik Heiland, Anusha Mishra, Robert Zorec, Levi B. Wood, Marc R. Freeman, Matthew Holt, Luis Barbeito, Gabor C. Petzold, Luc Pellerin, Jeffrey D. Rothstein, Nathalie Rouach, Carole Escartin, Schuichi Koizumi, Gertrudis Perea, Dwight E. Bergles, Miriam Riquelme-Perez, Martine Cohen-Salmon, Stefanie Robel, James E. Goldman, Binhai Zheng, João Filipe Oliveira, Ari Barzilai, Steven A. Goldman, Brian A. MacVicar, Aude Panatier, Helmut Kettenmann, Alexei Verkhratsky, Amit Agarwal, Colm Cunningham, Blanca Diaz-Castro, Francisco J. Quintana, Milos Pekny, Harald Sontheimer, Benjamin Deneen, Vladimir Parpura, Service MIRCEN (MIRCEN), Institut de Biologie François JACOB (JACOB), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Universitat Autònoma de Barcelona (UAB), ICREA Infection Biology Laboratory (Department of Experimental and Health Sciences), Universitat Pompeu Fabra [Barcelona] (UPF), University of Cambridge [UK] (CAM), National Institute for Occupational Safety and Health [Morgantown, WV, USA] (NIOSH), German Research Center for Neurodegenerative Diseases - Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), University Hospital Bonn, Massachusetts General Hospital [Charlestown, MA, États-Unis], University of Bonn, University of Lausanne (UNIL), Italian National Research Council [Padova, Italy], University of Padua [Italy], Heidelberg University, The Salk Institute for Biological Studies, University of Minnesota [MN, USA], Institut Pasteur de Montevideo, Réseau International des Instituts Pasteur (RIIP), Tel Aviv University [Tel Aviv], Johns Hopkins University School of Medicine [Baltimore], University of Portsmouth, Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Centre interdisciplinaire de recherche en biologie (CIRB), Labex MemoLife, École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Collège de France (CdF (institution))-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Collège de France (CdF (institution))-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Trinity College Dublin, Baylor College of Medicine (BCM), Baylor University, University College of London [London] (UCL), University of Edinburgh, San Raffaele Scientific Institute, Vita-Salute San Raffaele University and Center for Translational Genomics and Bioinformatics, Vollum Institute, Vollum Institute OHSU, National Children's Hospital, Columbia University [New York], University of Rochester Medical Center (URMC), University of Copenhagen = Københavns Universitet (KU), Ludwig Maximilians Universitaet, SYNERGY, Excellence Cluster of Systems Neurology, Ludwig-Maximilians-Universität München (LMU), Universidad de Málaga [Málaga] = University of Málaga [Málaga], Centro de Investigacion Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III [Madrid] (ISC), Tufts University School of Medicine [Boston], University of Freiburg [Freiburg], Utrecht University [Utrecht], VIB-KU Leuven Center for Brain & Disease Research [Leuven, Belgium], Nihon University School of Medicine [Tokyo, Japan], Max Delbrück Center for Molecular Medicine [Berlin] (MDC), Helmholtz-Gemeinschaft = Helmholtz Association, David Geffen School of Medicine [Los Angeles], University of California [Los Angeles] (UCLA), University of California-University of California, Yamanashi University, Institute for Basic Science [Daejeon] (IBS), New York University School of Medicine (NYU), New York University School of Medicine, NYU System (NYU)-NYU System (NYU), University of British Columbia (UBC), King Abdullah University of Science and Technology, University of Wisconsin-Madison, Oregon Health and Science University [Portland] (OHSU), University of California [San Francisco] (UCSF), University of California, McGill University Health Center [Montreal] (MUHC), University of Kentucky, Kyushu University [Fukuoka], Physiopathologie de la Plasticité Neuronale (Neurocentre Magendie - U1215 Inserm), Université de Bordeaux (UB)-Institut François Magendie-Institut National de la Santé et de la Recherche Médicale (INSERM), University of Minho [Braga], ICVS/3B's—PT Government Associate Laboratory [Braga, Portugal], Polytechnic Institute of Cávado and Ave, University of Alabama at Birmingham [ Birmingham] (UAB), University of Gothenburg (GU), Ischémie Reperfusion en Transplantation d’Organes Mécanismes et Innovations Thérapeutiques ( IRTOMIT), Université de Poitiers-Institut National de la Santé et de la Recherche Médicale (INSERM), Cajal Institute, King‘s College London, Institut des Neurosciences Cellulaires et Intégratives (INCI), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Brigham & Women’s Hospital [Boston] (BWH), Harvard Medical School [Boston] (HMS), Third Rock Ventures, Heinrich Heine Universität Düsseldorf = Heinrich Heine University [Düsseldorf], Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry (IBCh RAS), Russian Academy of Sciences [Moscow] (RAS), Sechenov First Moscow State Medical University, Ludwig Maximilian University [Munich] (LMU), Institute for Stem Cell Research [Neuherberg], Helmholtz-Zentrum München (HZM), Universidad de Sevilla, Georgia Institute of Technology [Atlanta], The University of Texas Health Science Center at Houston (UTHealth), UC San Diego School of Medicine, Universidade Federal do Rio Grande do Sul [Porto Alegre] (UFRGS), University of Ljubljana, University of Manchester [Manchester], Ikerbasque - Basque Foundation for Science, Université Paris-Saclay-Institut de Biologie François JACOB (JACOB), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), European Project: 722053,EU-GliaPhD - H2020-EU.1.3. H2020-EU.1.3.1., Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Collège de France (CdF (institution))-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie François JACOB (JACOB), Universität Bonn = University of Bonn, Université de Lausanne = University of Lausanne (UNIL), Escartin, Carole [0000-0003-3613-4118], Galea, Elena [0000-0003-4537-9897], Lakatos, András [0000-0002-1301-2292], Petzold, Gabor C [0000-0002-0145-8641], Serrano-Pozo, Alberto [0000-0003-0899-7530], Volterra, Andrea [0000-0003-1069-1602], Araque, Alfonso [0000-0003-3840-1144], Barbeito, Luis [0000-0002-3047-232X], Bonvento, Gilles [0000-0002-2886-4228], Butt, Arthur M [0000-0001-7579-0746], Deneen, Benjamin [0000-0002-6335-1081], Farina, Cinthia [0000-0002-4466-9676], Gallo, Vittorio [0000-0002-2429-0845], Goldman, Steven A [0000-0002-5498-4303], Götz, Magdalena [0000-0003-1551-9203], Gutiérrez, Antonia [0000-0002-6264-6152], Haydon, Philip G [0000-0001-5698-6698], Heiland, Dieter H [0000-0002-9258-3033], Hol, Elly M [0000-0001-5604-2603], Holt, Matthew G [0000-0002-8958-4027], Koizumi, Schuichi [0000-0001-6184-3106], MacVicar, Brian A [0000-0003-4596-4623], Mishra, Anusha [0000-0002-3642-5049], Molofsky, Anna V [0000-0002-4709-2411], Okada, Seiji [0000-0002-5107-8209], Oliveira, João F [0000-0002-1005-2328], Panatier, Aude [0000-0002-6107-4463], Pekna, Marcela [0000-0003-2734-8237], Perea, Gertrudis [0000-0001-5924-9175], Pfrieger, Frank W [0000-0001-7085-1431], Poskanzer, Kira E [0000-0003-4830-8891], Rose, Christine R [0000-0002-9684-3592], Rothstein, Jeffrey D [0000-0003-2001-8470], Rouach, Nathalie [0000-0002-5574-888X], Rowitch, David H [0000-0002-0079-0060], Semyanov, Alexey [0000-0002-6800-0942], Sirko, Swetlana [0000-0001-5950-616X], Sontheimer, Harald [0000-0002-5843-9871], Swanson, Raymond A [0000-0002-3664-5359], Zorec, Robert [0000-0002-7478-3875], Sofroniew, Michael V [0000-0001-6075-0178], Verkhratsky, Alexei [0000-0003-2592-9898], and Apollo - University of Cambridge Repository

Subjects
0301 basic medicine, Aging, [SDV]Life Sciences [q-bio], Disease, pathology [Spinal Cord], Article, 03 medical and health sciences, 0302 clinical medicine, pathology [Aging], Response to injury, pathology [Brain], medicine, Psychology, Animals, Humans, ddc:610, Reactive Astrocyte, ComputingMilieux_MISCELLANEOUS, Spinal Cord Injuries, pathology [Astrocytes], Brain Diseases, Neurology & Neurosurgery, Extramural, business.industry, General Neuroscience, pathology [Brain Injuries], Neurosciences, pathology [Brain Diseases], Brain, 3. Good health, Brain Disorders, 030104 developmental biology, medicine.anatomical_structure, Spinal Cord, Astrocytes, Brain Injuries, Neurological, Cognitive Sciences, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], pathology [Spinal Cord Injuries], business, Neuroscience, 030217 neurology & neurosurgery, Astrocyte, Spinal cord pathology
Abstract

Reactive astrocytes are astrocytes undergoing morphological, molecular, and functional remodeling in response to injury, disease, or infection of the CNS. Although this remodeling was first described over a century ago, uncertainties and controversies remain regarding the contribution of reactive astrocytes to CNS diseases, repair, and aging. It is also unclear whether fixed categories of reactive astrocytes exist and, if so, how to identify them. We point out the shortcomings of binary divisions of reactive astrocytes into good-vs-bad, neurotoxic-vs-neuroprotective or A1-vs-A2. We advocate, instead, that research on reactive astrocytes include assessment of multiple molecular and functional parameters—preferably in vivo—plus multivariate statistics and determination of impact on pathological hallmarks in relevant models. These guidelines may spur the discovery of astrocyte-based biomarkers as well as astrocyte-targeting therapies that abrogate detrimental actions of reactive astrocytes, potentiate their neuro- and glioprotective actions, and restore or augment their homeostatic, modulatory, and defensive functions., Funding: CNRS, CEA, ANR, and France Alzheimer to CE.; MCINN (PID2019-107633RB-I00) and Generalitat de Catalunya (2017-SGR547, Grup de demències Sant Pau) to E.G. US Centers for Disease Control and Prevention to J. P.O. Alzheimer’s Association (AACF-17-524184) and NIH-NIA (K08AG064039) to A.S.-P. DFG (SPP1757, STE 552/5, STE 552/4), EU (H2020-MSCA-ITN project 722053 EU-GliaPhD) and BMBF (16GW0182 CONNEXIN) to C.S. Swiss National Science Foundation grant 31003A 173124/1; SNSF NCCR ‘Transcure’ (51NF40-160620); Synapsis Foundation Heidi Seiler-Stiftung 2018-PI01 to A.Volterra. NIH-NINDS (NS084030), Dr. Miriam and Sheldon G. Adelson Medical Foundation and Wings for Life to M.V.S. The authors thank T. Yohannan of Alpha Language Services, Barcelona, for expert copy editing.

Published
2021
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96. Nuclear structure of Te isotopes beyond neutron magic number N=82

Author

Y. Shimizu, Giuseppe Lorusso, F. L. Bello Garrote, I. Nishizuka, T. Isobe, Chang-Bum Moon, A. Jungclaus, S. Morimoto, Naohito Inabe, Y. F. Fang, Zs. Vajta, Hiroshi Watanabe, Roman Gernhäuser, C. S. Lee, Hiroshi Suzuki, Toshiyuki Sumikama, Shunji Nishimura, H. Schaffner, M. Si, D. Mücher, Hiroyuki Takeda, Daichi Murai, F. Browne, Hiroki Nishibata, Atsuko Odahara, Anna Wendt, J. M. Daugas, Guillaume Gey, L. Sinclair, Hiroyoshi Sakurai, I. Kojouharov, P. A. Söderström, Ayumi Yagi, S. Bönig, Byung-Sik Hong, Gary Simpson, R. Orlandi, Younghun Kwon, A. Montaner-Pizá, Stephen Rice, D. Kameda, J. M. Keatings, Eiji Ideguchi, Rin Yokoyama, K. Moschner, A. Gargano, S. Ilieva, Jan Taprogge, K. Yoshinaga, Hyo Soon Jung, B. Moon, R. Daido, Zena Patel, D. S. Ahn, P. Doornenbal, Jin Wu, H. Naïdja, K. Tshoo, N. Kurz, K. Steiger, Naoki Fukuda, Megumi Niikura, P. Lee, F. Didierjean, Tetsuro Komatsubara, Toshiyuki Kubo, T. Kröll, R. Lozeva, F. Drouet, Z. H. Li, H. Baba, Zhengyu Xu, T. Ishigaki, RIKEN Nishina Center for Accelerator-Based Science, University of Tokyo, Institute for Basic Science (South Korea), National Research Foundation of Korea, Ministerio de Economía y Competitividad (España), Japan Society for the Promotion of Science, National Research, Development and Innovation Office (Hungary), Institut Pluridisciplinaire Hubert Curien (IPHC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Institut Laue-Langevin (ILL), ILL, Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), and Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Physics, Isotope, [PHYS.NUCL]Physics [physics]/Nuclear Theory [nucl-th], 010308 nuclear & particles physics, Nuclear Theory, Nuclear structure, Nuclear Structure, 7. Clean energy, 01 natural sciences, Nuclear physics, Fragmentation (mass spectrometry), Excited state, 0103 physical sciences, Neutron, 010306 general physics, Nucleon, Nuclear Experiment, Beam (structure), Magic number (physics)
Abstract

15 pags., 10 figs., 4 tabs., Newly observed decay schemes of the nuclei Sb137 and Sb138 are reported. The neutron-rich Sb isotopes were produced by the in-flight fragmentation of a U238 primary beam with an energy of 345 MeV/nucleon. Several new excited states of Te137 with tentatively assigned spin-parities of (5/2-), (9/2-), and (7/2) have been established which play an important role in the evolution of neutron levels beyond N=82. The study of the ß decay of Sb138 led to a considerable extension of the level scheme of Te138 including the identification of several nonyrast states. The structure of Te137 and Te138 is discussed on the basis of large-scale shell-model calculations performed using two different effective interactions., This work was carried out at the RIBF operated by RIKEN Nishina Center and CNS, University of Tokyo. Part of the WAS3ABi was supported by the Rare Isotope Science Project (RISP) of the Institute for Basic Science (IBS) funded by the Ministry of Science, ICT and Future Planning (MSIP) and National Research Foundation (NRF) of the Republic of Korea (Grant No. 2013M7A1A1075764). This research was supported by NRF of the Republic of Korea (Grants No. 2019R1A6A3A03031564 and No. 2018R1A5A1025563), IBS of the Republic of Korea (Grants No. IBS-R031-D1 and No. IBS-R031-Y1), the Spanish Ministerio de Economía y Competitividad (Grant No. FPA2017-84756-C4-2-P), and JSPS KAKENHI of Japan (Grant No. 25247045). The support from FR-JP LIA is also acknowledged. C.S.L. acknowledges the support from NRF of the Republic of Korea (Grants No. 2017M2A2A6A02071071 and No. 2016R1D1A1A09917463). Z.V. acknowledges the supports from the National Research, Development and Innovation Fund of Hungary, financed under the K18 funding scheme with Project No. K128947 and by the European Regional Development Fund (Grant No. GINOP-2.3.3-15-2016- 00034), as well as by the National Research, Development and Innovation Office NKFIH (Grant No. PD 124717).

Published
2021
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97. Investigation of the ground-state spin inversion in the neutron-rich isotopes

Author

Linh, B.D., Corsi, A., Gillibert, A., Obertelli, A., Doornenbal, P., Barbieri, C., Chen, S., Chung, L.X., Duguet, Thomas, Gómez-Ramos, M., Holt, J.D., Moro, A., Navrátil, P., Ogata, K., Phuc, N.T.T., Shimizu, N., Somà, V., Utsuno, Y., Achouri, N.L., Baba, H., Browne, F., Calvet, D., Château, F., Chiga, N., Cortés, M.L., Delbart, A., Gheller, J.M., Giganon, A., Hilaire, C., Isobe, T., Kobayashi, T., Kubota, Y., Lapoux, V., Liu, H.N., Motobayashi, T., Murray, I., Otsu, H., Panin, V., Paul, N., Rodriguez, W., Sakurai, H., Sasano, M., Steppenbeck, D., Stuhl, L., Sun, Y.L., Togano, Y., Uesaka, T., Wimmer, K., Yoneda, K., Vaquero, Victor, RIKEN Nishina Center for Accelerator-Based Science, European Commission, Ministry of Science and Technology of Vietnam, Ministerio de Ciencia, Innovación y Universidades (España), Helmholtz International Center for FAIR, Croatian Science Foundation, German Research Foundation, Institute for Basic Science (South Korea), Federal Ministry of Education and Research (Germany), National Research, Development and Innovation Office (Hungary), Japan Society for the Promotion of Science, National Research Council of Canada, Department of Energy (US), Oak Ridge National Laboratory (US), University of Leicester, Science and Technology Facilities Council (UK), and Natural Sciences and Engineering Research Council of Canada

Abstract

16 pags., 9 figs., 5 tabs., A first -ray study of spectroscopy was performed at the Radioactive Isotope Beam Factory with projectiles at 217 MeV/nucleon, impinging on the liquid hydrogen target of the MINOS device. Prompt deexcitation rays were measured with the NaI(Tl) array DALI2. Through the one-proton knockout reaction , a spin assignment could be determined for the low-lying states of from the momentum distribution obtained with the SAMURAI spectrometer. A spin-parity is deduced for the ground state of , similar to the recently studied isotope . The evolution of the energy difference is compared to state-of-the-art theoretical predictions., We thank the RIKEN Nishina Center accelerator staff for their work in the primary beam delivery and the BigRIPS team for preparing the secondary beams. The development of MINOS has been supported by the European Research Council through the ERC Grant No. MINOS258567. B.D.L., L.X.C., and N.D.T. acknowledge support from the Vietnam Ministry of Science and Technology under Grant No. ĐTCB.01/21/VKHKTHN. M.G.R. and A.M.M. are supported by the Spanish Ministerio de Ciencia, Innovación y Universidades (including FEDER funds) under project FIS2017-88410-P. F.B. was supported by the RIKEN Special Postdoctoral Researcher Program. Y.L.S. acknowledges the support of Marie Skłodowska-Curie Individual Fellowship (H2020-MSCAIF-2015-705023) from the European Union. I.G. has been supported by HIC for FAIR and Croatian Science Foundation. R.-B.G. is supported by the Deutsche Forschungsgemeinschaft (DFG) under Grant No. BL 1513/1-1. K.I.H., D.K., and S.Y.P. acknowledge the support from the IBS grant funded by the Korea government (No. IBS-R031-D1). P.K. was supported in part by the BMBF Grant No. 05P19RDFN1 and HGS-HIRe. D.So. has been supported by the European Regional Development Fund Contract No. GINOP-2.3.3-15-2016-00034 and the National Research, Development and Innovation Fund of Hungary via Project No. K128947. This work was supported in part by JSPS KAKENHI Grants No. JP16H02179, No. JP18H05404, and No. JP20K03981. J.D.H. and R.S. acknowledge the support from NSERC and the National Research Council Canada. This work was supported by the Office of Nuclear Physics, U.S. Department of Energy, under Grants No. de-sc0018223 (NUCLEI SciDAC-4 collaboration) and the FieldWork Proposal ERKBP72 at Oak Ridge National Laboratory (ORNL). Computer time was provided by the Innovative and Novel Computational Impact on Theory and Experiment (INCITE) program. This research used resources of the Oak Ridge Leadership Computing Facility located at ORNL, which is supported by the Office of Science of the Department of Energy under Contract No. DE-AC05-00OR22725. GGF calculations were performed by using HPC resources from GENCI-TGCC (Contracts No. A007057392 and No. A009057392) and at the DiRAC Complexity system at the University of Leicester (BIS National E-infrastructure capital Grant No. ST/K000373/1 and STFC Grant No. ST/K0003259/1). This work was supported by the United Kingdom Science and Technology Facilities Council (STFC) under Grant No. ST/L005816/1 and in part by the NSERC Grants No. SAPIN-2016-00033, No. SAPIN-2018-00027, and No. RGPAS-2018-522453. TRIUMF receives federal funding via a contribution agreement with the National Research Council of Canada. J.D.H. thanks S. R. Stroberg for the IMSRG++ code used to perform the VSIMSRG calculations [86]. N.T.T.P. was funded by Vingroup Joint Stock Company and supported by the Domestic Ph.D. Scholarship Programme of Vingroup Innovation Foundation (VINIF), Vingroup Big Data Institute (VINBIGDATA), code VINIF.2020.TS.52.

Published
2021

98. Nonlinear forced change and nonergodicity: The case of ENSO-Indian monsoon and global precipitation teleconnections

Author

Tamás Bódai, Gábor Drótos, Kyung-Ja Ha, June-Yi Lee, Eui-Seok Chung, Institute for Basic Science (South Korea), Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), European Commission, National Research, Development and Innovation Office (Hungary), Govern de les Illes Balears, Department of Energy (US), and National Oceanic and Atmospheric Administration (US)

Subjects
010504 meteorology & atmospheric sciences, Correlation coefficient, ENSO-Indian monsoon teleconnection, Empirical orthogonal functions, Forced response, Forcing (mathematics), 01 natural sciences, Physics::Geophysics, Canonical correclation analysis, 0103 physical sciences, Predictability, snapshot attractor, lcsh:Science, 010306 general physics, Physics::Atmospheric and Oceanic Physics, 0105 earth and related environmental sciences, Mathematics, Snapshot attractor, Monsoon of South Asia, Global precipitation, ensemble, Ergodicity, Nonlinear system, Sea surface temperature, El Niño Southern Oscillation, maximum covariance analysis, Climatology, Maximum covariance analysis, Environmental science, ergodicity, General Earth and Planetary Sciences, lcsh:Q, Canonical correlation, forced response, Ensemble, Teleconnection
Abstract

We study the forced response of the teleconnection between the El Niño–Southern Oscillation (ENSO) and the Indian summer monsoon (IM) in the Max Planck Institute Grand Ensemble, a set of Earth system ensemble simulations under historical and Representative Concentration Pathway (RCP) forcing. The forced response of the teleconnection, or a characteristic of it, is defined as the time dependence of a correlation coefficient evaluated over the ensemble. We consider the temporal variability of spatial averages and that with respect to dominant spatial modes in the sense of Maximal Covariance Analysis, Canonical Correlation Analysis and Empirical Orthogonal Function analysis across the ensemble. A further representation of the teleconnection that we define here takes the point of view of the predictability of the spatiotemporal variability of the Indian summer monsoon. We find that the strengthening of the ENSO-IM teleconnection is robustly or consistently featured in view of various teleconnection representations, whether sea surface temperature (SST) or sea level pressure (SLP) is used to characterize ENSO, and both in the historical period and under the RCP8.5 forcing scenario. It is found to be associated dominantly with the principal mode of ENSO variability. Concerning representations that involve an autonomous characterisation of the Pacific, in terms of a linear regression model, the main contributor to the strengthening is the regression coefficient, which can outcompete even a declining ENSO variability when it is represented by SLP. We also find that the forced change of the teleconnection is typically nonlinear by 1) formally rejecting the hypothesis that ergodicity holds, i.e., that expected values of temporal correlation coefficients with respect to the ensemble equal the ensemble-wise correlation coefficient itself, and also showing that 2) the trivial contributions of the forced changes in means and standard deviations are insignificant here. We also provide, in terms of the test statistics, global maps of the degree of nonlinearity/nonergodicity of the forced change of the teleconnection between local precipitation and ENSO., TB was supported by the Institute for Basic Science (IBS), under IBS-R028-D1. G.D. acknowledges financial support from the Spanish State Research Agency through the María de Maeztu Program for Units of Excellence in R&D under grant no. MDM-2017-0711, from the National Research, Development and Innovation Office (NKFIH, Hungary) under grant nos. K125171 and FK-124256, and from the European Social Fund through the fellowship no. PD/020/2018 under the postdoctoral program of the Government of the Balearic Islands (CAIB, Spain). Support for the Twentieth Century Reanalysis Project dataset is provided by the U.S. Department of Energy, Office of Science Innovative and Novel Computational Impact on Theory and Experiment (DOE INCITE) program, and Office of Biological and Environmental Research (BER), by the National Oceanic and Atmospheric Administration Climate Program Office, and by the National Oceanic and Atmospheric Administration Climate Program Office, and by the NOAA Physical Sciences Laboratory.

Published
2021

100. Physical methods for mechanistic understanding: general discussion

Author

Jonathan D. Wilden, Simone Gallarati, Jennifer A. Love, David J. Nelson, Samuel Scott, Thomas Braun, David Schilter, Matthias Bauer, Aaron L. Odom, David L. Davies, Robert H. Morris, Vidar R. Jensen, Tolga Yaman, Jana Roithova, Yutaka Aoki, Kevin R. J. Lovelock, Alexander J Hamilton, Evert Jan Meijer, Jason M. Lynam, James W. Walton, Meghan E. Halse, Alison N. Hulme, Joseph S. Renny, Youichi Ishii, Shigeki Kuwata, Robin N. Perutz, Stuart MacGregor, Aiwen Lei, Laurel L. Schafer, Jamie A. Cadge, Martin Jakoobi, John M. Slattery, Todd B. Marder, Derek J. Durand, Ian J. S. Fairlamb, Guy C. Lloyd-Jones, Pierre Kennepohl, Natalie Fey, M. George, Odile Eisenstein, Ulrich Hintermair, Anthony Haynes, Megan Greaves, Markus Reiher, Jeremy N. Harvey, Daniel H. Ess, Patrick Morgan, Joseph M. Mwansa, Tom A. Young, Chun-Yuen Wong, Institut Charles Gerhardt Montpellier - Institut de Chimie Moléculaire et des Matériaux de Montpellier (ICGM ICMMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Université Montpellier 1 (UM1)-Université Montpellier 2 - Sciences et Techniques (UM2)-Institut de Chimie du CNRS (INC), Brigham Young University (BYU), Department of Chemistry [York, UK], University of York [York, UK], University of Bristol [Bristol], Department of Chemistry, University of Bergen (UiB), Medical Informatics Division, Tottori University Hospital, Heriot-Watt University [Edinburgh] (HWU), University of Würzburg, Universiteit van Amsterdam (UvA), Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich), Department of Organic Chemistry [Prague], University of Chemistry and Technology Prague (UCT Prague), Department of Chemistry [Vancouver] (UBC Chemistry), University of British Columbia (UBC), and Center for Multidimensional Carbon Materials, Institute for Basic Science (IBS) (CMCM)

Subjects
h-2, spectroscopy, 02 engineering and technology, spin states, ligand, 010402 general chemistry, 01 natural sciences, PI-SYMMETRY, ABSORPTION, Physical and Theoretical Chemistry, CARBON-MONOXIDE, ComputingMilieux_MISCELLANEOUS, SPIN STATES, H-2, Cognitive science, CATALYST, complexes, Science & Technology, SPECTROSCOPY, Chemistry, Physical, carbon-monoxide, [CHIM.CATA]Chemical Sciences/Catalysis, HYDROGEN, 021001 nanoscience & nanotechnology, 0104 chemical sciences, [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, Chemistry, pi-symmetry, hydrogen, Physical Sciences, COMPLEXES, LIGAND, 0210 nano-technology, Psychology, absorption, catalyst
Abstract

ispartof: FARADAY DISCUSSIONS vol:220 issue:0 pages:144-178 ispartof: location:England status: published

Published
2019
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