51. Impact of COVID-19 on COPD exacerbations and clinical course.
- Author
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Manzano, Carlos, Benitez, Ivan D, Santisteve, Sally, Monge, Aida, Moncusí-Moix, Anna, Gort-Paniello, Clara, Torres, Gerard, Barbé, Ferran, González, Jessica, and de Batlle, Jordi
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DISEASE exacerbation , *MENTAL health , *T-test (Statistics) , *RESEARCH funding , *QUESTIONNAIRES , *FISHER exact test , *DESCRIPTIVE statistics , *RETROSPECTIVE studies , *CHI-squared test , *OBSTRUCTIVE lung diseases , *QUALITY of life , *CASE-control method , *DATA analysis software , *COVID-19 , *DISEASE complications , *SYMPTOMS - Abstract
Background: COPD patients show higher mortality and worse prognosis in the acute phase of COVID-19, and survivors may suffer persistent symptoms that could make them more vulnerable to exacerbations. Objectives: We aimed to evaluate the impact of COVID-19 on the exacerbations, symptoms, quality of life, and mental health of a cohort of COPD patients. Methods: Retrospective case-control single-centre study including all COPD patients from the pulmonary consultation of University Hospital Santa Maria (Lleida, Spain) surviving COVID-19 between March 2020 and September 2021, and similar propensity-score-matched (1:2) COPD patients. Differences in COPD exacerbations, COPD clinical evolution (lung function, dyspnoea, CAT and symptoms), long COVID-19 symptoms, quality of life, and mental health, were assessed at the end of 2021. Results: We included 39 COVID-19 COPD patients and 78 similar non-COVID-19. No differences were found on exacerbations (46(59%) vs. 27(69.2%), p = 0.380), dyspnoea (2 [1; 3] vs. 2 [1; 3], p = 0.921) CAT (14.5 [10.0; 18.8] vs. 13.0 [10.0; 16.0], p = 0.432). Only the prevalence of smell or taste disorders, hair loss and tingling was higher in COVID-19 patients. No differences were found in quality of life or mental health. Conclusions: COPD patients surviving COVID-19 were not at a higher risk of COPD exacerbations nor showed significant changes in COPD clinical evolution, and only showed differences in a few very specific COVID-19 symptoms. These unexpected results suggest that the conditions triggered by the pandemic and its management could have affected COPD patients as much as actually having had COVID-19. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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