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In this article the author talks about the Fluoxetine, either alone or in combination with CBT, appears to be the most effective treatment for children and adolescents with moderate to severe depression, a systematic review and network meta-analysis has concluded.

The article offers information about how discontinuation of antidepressants too early raises risk of relapse. It mentions that British Association for Psychopharmacology's guideline recommends that all patients should take antidepressants for at least six-nine months after full remission, along with discusses risk factors associated with it.

The author reflects on the results of a multicohort study in Europe, which showed that people working in cognitively stimulating jobs are at reduced risk of dementia than those working in non-stimulating jobs. Also cited are the use of questionnaires to measure psychological demands and decision latitude (control) at work, and the four categories of work based on Karasek's Job Demands and Control model, including active, passive and high-strain.

The article offers information on the effectiveness of the antidepressants for back pain and osteoarthritis (OA). It mentions about the randomized placebo-controlled trials of any antidepressant drug and evidence regarding the potential benefits of serotonin–norepinephrine reuptake inhibitor (SNRIs) in OA and tricyclics (TCAs) or SNRIs in sciatica.

An editorial is presented on the role of the Edinburgh Postnatal Depression Scale. Topics include the postnatal depression has not been shown to improve maternal and infant outcomes, the unless all false positives are recognised immediately there is a risk of over diagnosis and overtreatment of depression, and the clinical assessment is also unclear as it is neither a diagnostic tool nor an accurate measure of depression severity.

The article informs that according to a English Longitudinal Study of Ageing, loneliness is associated with an increased risk of depression. It mentions that causal link between loneliness and depression is plausible, with a number of potential mediators, and perceived social isolation is tantamount to feeling unsafe and this may lead to anxiety, insomnia, social distancing behaviour and low self-esteem.

The article focuses on statin use is associated with a reduced risk of depression and does not increase the risk of suicide, anxiety or seizures, a Swedish national cohort study has found. Topics include the cohort has comprised all individuals aged 15 years and over who were prescribed statins between January 2006 and December 2013, and the incidence of the defined outcomes during periods of treatment and non-treatment has compared.

An editorial is presented on the Delirium is associated with an increased risk of subsequent cognitive decline and there is evidence to suggest that the association is causal, a systematic review and meta-analysis has found. Topics icnlude the relevant observational studies has were identified from electronic databases, and the most studies used the Confusion Assessment Method (CAM) to identify delirium.

The article reports that according to a study in Great Britain, sedentary behavior during adolescence is associated with an increased risk of depressive symptoms at the age of 18. It mentions that depressive symptoms (score range 0-21) as measured at age 18 with the self-administered computerized Clinical.

An editorial is presented which discusses The children of mothers who experience perinatal depression are more likely to report psychotic experiences at the age of 18, a UK prospective cohort study has found; The Avon Longitudinal Study of Parents and Children recruited 14,541 women during pregnancy in 1991-9; and Perinatal depression symptoms were measured with the Edinburgh Postnatal Depression Scale (EPDS) at 18 and 32 weeks antenatally, and at 8 weeks and 8 months postnatally.

The article informs about the Royal Colleges and other medical organizations invited members to take part via newsletters, email, websites and social media. It mentions that the survey incorporated a test of resilience and the Professional Quality of Life Scale, which measures burnout, secondary traumatic stress and compassion satisfaction. It also informs that doctors had the optimal combination of low burnout, low secondary traumatic stress and high compassion satisfaction.

The article looks at a cohort study by researcher E. Netsi and others published in "JAMA Psychiatry" which found that children of women with severe persistent postnatal depression (PND) are at substantially increased risk of preschool behaviour problems and adolescent depression. It also mentions risk of adverse outcomes is particularly high for those with severe persistent depression. It also mentions adjunctive parenting intervention which is effective than relaxation therapy.

The article presents the result of English death registrations analysis that showed male doctors have a lower suicide risk than the general male population. It mentions as according to World Health Organization recommendations a suicide risk assessment should be undertaken for all patients with a mental health disorder and also highlights the result of a study in which compared Great Britain suicide rates.

The article highlights Hormone replacement therapy (HRT) which increase the risk of Alzheimer's disease. Topics include majority of the Alzheimer's disease cases at the aged more than 60 years at the time diagnosis; HRT use for less than 10 years in aged under 60 which did not increase the risk; and hormone therapy users informed of a possible risk of the disease.

The article focuses on the heavy menstrual bleeding loss in women of reproductive age, classification of abnormal uterine bleeding (AUB) and women with pelvic pain.

The article presents key points related to chronic obstructive pulmonary disease (COPD), which is a common lung condition in people aged over 40 years. It discusses the diagnosis of COPD based on the post-bronchodilator spirometry, prescription of amoxicillin, doxycycline and clarithromycin, specialist review referral is needed in case of diagnostic uncertainty.

The article focuses on the uncertainty in reducing the risk of dementia by the intensive blood pressure (BP) control. although it reduced the risk of mild cognitive impairment. It discusses the encouragement of thiazide-type diuretics, assessment of cognitive status, the response of median follow-up after incident probable dementia in the standard treatment group of hazard ratio (HR).

The article focuses on the high risk of suicides among patients diagnosed with cancer as per the data released by Public Health England's national cancer registration database. It discusses the follow-up of after diagnosis of cancer revealing greater number of men suicide than women, standardised mortality rate.