51. The right dorsal premotor mosaic: Organization, functions, and connectivity
- Author
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Hai Li, Svenja Caspers, Felix Hoffstaedter, Katrin Amunts, Sarah Genon, Robert Langner, Simon B. Eickhoff, Tianzi Jiang, Veronika I. Müller, Christian Grefkes, Susanne Moebus, Andrew T. Reid, Lingzhong Fan, Edna C. Cieslik, and Peter T. Fox
- Subjects
Cognitive Neuroscience ,Rest ,Medizin ,chemical and pharmacologic phenomena ,Brain mapping ,050105 experimental psychology ,Premotor cortex ,03 medical and health sciences ,Cellular and Molecular Neuroscience ,0302 clinical medicine ,Task-positive network ,Motor system ,Neural Pathways ,medicine ,Humans ,0501 psychology and cognitive sciences ,ddc:610 ,Prefrontal cortex ,Brain Mapping ,Working memory ,05 social sciences ,Motor Cortex ,Cognition ,Original Articles ,Cognitive artificial intelligence ,Magnetic Resonance Imaging ,Brain Networks and Neuronal Communication [DI-BCB_DCC_Theme 4] ,medicine.anatomical_structure ,nervous system ,Psychology ,Neuroscience ,030217 neurology & neurosurgery ,Motor cortex - Abstract
Contains fulltext : 169032.pdf (Publisher’s version ) (Closed access) The right dorsal premotor cortex (PMd) of humans has been reported to be involved in a broad range of motor and cognitive functions. We explored the basis of this behavioral heterogeneity by performing a connectivity-based parcellation using meta-analytic approach applied to PMd coactivations. We compared our connectivity-based parcellation results with parcellations obtained through resting-state functional connectivity and probabilistic diffusion tractography. Functional connectivity profiles and behavioral decoding of the resulting PMd subregions allowed characterizing their respective behavior profile. These procedures divided the right PMd into 5 distinct subregions that formed a cognitive-motor gradient along a rostro-caudal axis. In particular, we found 1) a rostral subregion functionally connected with prefrontal cortex, which likely supports high-level cognitive processes, such as working memory, 2) a central subregion showing a mixed behavioral profile and functional connectivity to parietal regions of the dorsal attention network, and 3) a caudal subregion closely integrated with the motor system. Additionally, we found 4) a dorsal subregion, preferentially related to hand movements and connected to both cognitive and motor regions, and 5) a ventral subregion, whose functional profile fits the concept of an eye movement-related field. In conclusion, right PMd may be considered as a functional mosaic formed by 5 subregions. 16 p.
- Published
- 2017