446 results on '"Kazumasa Yamagishi"'
Search Results
402. The criteria for metabolic syndrome and the national health screening and education system in Japan.
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Kazumasa Yamagishi, Hiroyasu Iso, Yamagishi, Kazumasa, and Iso, Hiroyasu
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Two major definitions of metabolic syndrome have been proposed. One focuses on the accumulation of risk factors, a measure used by the American Heart Association (AHA) and the National Heart, Lung, and Blood Institute (NHLBI); the other focuses on abdominal obesity, a measure used by the International Diabetes Federation (IDF) and the Japanese government. The latter definition takes waist circumference (WC) into consideration as an obligatory component, whereas the former does not. In 2009, the IDF, NHLBI, AHA, and other organizations attempted to unify these criteria; as a result, WC is no longer an obligatory component of those systems, while it remains obligatory in the Japanese criteria. In 2008, a new Japanese cardiovascular screening and education system focused on metabolic syndrome was launched. People undergoing screening are classified into three groups according to the presence of abdominal obesity and the number of metabolic risk factors, and receive health educational support from insurers. This system has yielded several beneficial outcomes: the visibility of metabolic syndrome at the population level has drastically improved; preventive measures have been directed toward metabolic syndrome, which is expected to become more prevalent in future generations; and a post-screening education system has been established. However, several problems with the current system have been identified and are under debate. In this review, we discuss topics related to metabolic syndrome, including (1) the Japanese criteria for metabolic syndrome; (2) metabolic syndrome and the universal health screening and education system; and (3) recent debates about Japanese criteria for metabolic syndrome. [ABSTRACT FROM AUTHOR]
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- 2017
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403. Usual alcohol consumption and arterial oxygen desaturation during sleep
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Hiroyasu Iso, Takashi Shimamoto, Isao Muraki, Kazumasa Yamagishi, Takeshi Tanigawa, Mitsumasa Umesawa, and Naoko Tachibana
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Adult ,Male ,Alcohol Drinking ,business.industry ,Arterial oxygen ,chemistry.chemical_element ,General Medicine ,Middle Aged ,Oxygen ,Sleep in non-human animals ,Sleep Apnea Syndromes ,chemistry ,Sleep apnea syndromes ,Anesthesia ,Medicine ,Humans ,Oximetry ,business ,Sleep ,Alcohol consumption ,Aged - Published
- 2004
404. Serum total homocysteine concentrations and risk of stroke and its subtypes in Japanese
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Takeshi Tanigawa, Tomonori Okamura, Hironori Imano, Kazumasa Yamagishi, Takashi Shimamoto, Yoshihiko Naito, Shinichi Sato, Tetsuya Ohira, Yuri Moriyama, Akihiko Kitamura, and Hiroyasu Iso
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Adult ,Brain Infarction ,Male ,medicine.medical_specialty ,Homocysteine ,Brain Ischemia ,chemistry.chemical_compound ,Japan ,Risk Factors ,Physiology (medical) ,Internal medicine ,Epidemiology ,Odds Ratio ,Medicine ,Humans ,Prospective Studies ,Risk factor ,Prospective cohort study ,Stroke ,Aged ,Aged, 80 and over ,business.industry ,Incidence (epidemiology) ,Incidence ,Case-control study ,Odds ratio ,Middle Aged ,medicine.disease ,Surgery ,chemistry ,Case-Control Studies ,Female ,Cardiology and Cardiovascular Medicine ,business ,Intracranial Hemorrhages - Abstract
Background— To date, no prospective studies have examined the association between serum homocysteine levels and the risk of stroke and stroke subtypes in Asian populations. Methods and Results— A prospective, nested, case-control study of Japanese subjects 40 to 85 years of age was conducted by using frozen serum samples from 11 846 participants in cardiovascular risk surveys collected from 1984 to 1995 for one community and 1989 to 1995 for the other two communities. By the end of 2000, we identified 150 incident strokes, the subtypes of which were confirmed by imaging studies. Three control subjects per case were selected by matching for sex, age, community, year of serum storage, and fasting status. Serum total homocysteine levels were measured by high-performance liquid chromatography. Compared with control subjects, total (n=150), hemorrhagic (n=52), and ischemic (n=98) strokes had higher geometric mean values of total homocysteine and higher proportions of homocysteine ≥11.0 μmol/L. The multivariate odds ratios (95% CI) for highest (≥11.0 μmol/L) versus lowest quartiles ( Conclusions— High total homocysteine concentrations were associated with the increased risk of total stroke, more specifically ischemic stroke and lacunar infarction, among Japanese men and women.
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- 2004
405. Type 2 diabetes and risk of non-embolic ischaemic stroke in Japanese men and women
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Takashi Shimamoto, Yoshihiko Naito, Tetsuya Ohira, Kazumasa Yamagishi, S. Sato, Minoru Iida, Takeshi Tanigawa, H. Imano, Hiroyasu Iso, and A. Kitamura
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Adult ,Blood Glucose ,Male ,medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,Blood Pressure ,Coronary Disease ,Type 2 diabetes ,Risk Assessment ,Cohort Studies ,Japan ,Diabetes mellitus ,Internal medicine ,Internal Medicine ,medicine ,Humans ,Risk factor ,Stroke ,Aged ,business.industry ,Absolute risk reduction ,Middle Aged ,medicine.disease ,Surgery ,Diabetes Mellitus, Type 2 ,Relative risk ,Cohort ,Hypertension ,Female ,business ,Diabetic Angiopathies ,Cohort study - Abstract
The aim of this study was to examine the relationship between type 2 diabetes and risk of ischaemic stroke in Asian populations. We conducted a 17-year prospective cohort study in 10,582 Japanese individuals (4287 men and 6295 women) aged 40–69 years living in five communities in Japan. All subjects were free of stroke and CHD at baseline. Diabetes was defined as a fasting glucose level of ≥7.0 mmol/l, a non-fasting glucose of ≥11.1 mmol/l, or receiving medication for diabetes. The risk of non-embolic ischaemic stroke was approximately two-fold higher in diabetic subjects than in subjects with normal glucose levels. The multivariate relative risk after adjustment for age, community, hypertensive status, BMI, triceps and subscapular skinfold thickness (TSF and SSF), and other known cardiovascular risk factors was 1.8 (95% CI 1.0–3.2) for men and 2.2 (1.2–4.0) for women. This excess risk was primarily observed among non-hypertensive subjects and individuals with higher values for measures of adiposity (BMI, TSF and SSF values above the median), particularly those with higher values for SSF. The association between non-embolic ischaemic stroke and glucose abnormality was particularly strong among non-hypertensive subjects with higher SSF values: the multivariate relative risk was 1.9 (1.0–3.7) for borderline diabetes and 4.9 (2.5–9.5) for diabetes. In this cohort, type 2 diabetes was a significant risk factor for non-embolic ischaemic stroke, particularly in non-hypertensive and non-lean individuals. Due to the nationwide decrease in blood pressure and increase in mean BMI among the Japanese population, with current levels approaching those observed in Western countries, the impact of glucose abnormalities on risk of ischaemic stroke represents a forthcoming public health issue in Japan.
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- 2004
406. Relationship between urinary cGMP excretion and serum total cholesterol levels in a general population
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Takashi Shimamoto, Takeshi Tanigawa, Hiroyasu Iso, Yoshito Kumagai, Renzhe Cui, Jingbo Pi, and Kazumasa Yamagishi
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Adult ,Male ,medicine.medical_specialty ,Urinary system ,Population ,Hypercholesterolemia ,Nitric Oxide ,Second Messenger Systems ,Excretion ,chemistry.chemical_compound ,Sex Factors ,Reference Values ,Internal medicine ,medicine ,Humans ,Endothelial dysfunction ,education ,Cyclic GMP ,Aged ,Creatinine ,education.field_of_study ,Cholesterol ,business.industry ,Age Factors ,Radioimmunoassay ,Middle Aged ,medicine.disease ,Endocrinology ,Cross-Sectional Studies ,chemistry ,Female ,Menopause ,Cardiology and Cardiovascular Medicine ,business ,Lipoprotein - Abstract
Hypercholesterolemia impairs endothelial function. However, the critical level of serum total cholesterol at which endothelial dysfunction occurs is unknown at present. We investigated cross-sectionally the correlation between urinary excretion of cyclic guanosine 3',5' monophosphate (cGMP), a second messenger of nitric oxide (NO) and serum total cholesterol concentrations in a general population sample of Japanese men and women. The samples comprised 1541 subjects (788 men and 753 women) aged 40-79 years, who participated in cardiovascular risk surveys between 1997 and 2002 and underwent a 24h urine collection. Urinary excretion of cGMP was measured using a (125)I-labeled cGMP radioimmunoassay and was adjusted for urinary creatinine excretion (nmol/mmol creatinine). The mean urinary cGMP excretion correlated linearly and inversely with serum total cholesterol level: mean cGMP excretion adjusted for age, sex and cardiovascular risk factors was 61.7, 53.6, 50.8, 49.2, 47.3 and 46.4 nmol/mmol for total cholesterol levels4.14, 4.14-4.64, 4.65-5.16, 5.17-5.68, 5.69-6.20 andor =6.21 mmol/L, respectively (p=0.007). This relation was more evident among individuals with end-organ damage, among subjects with higher C-reactive protein (CRP) levels and among postmenopausal women. Our data suggest a reduction of NO bioactivity with higher serum total cholesterol levels, even within clinically normal cholesterol levels.
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- 2004
407. [Body mass index and subsequent risk of hypertension, diabetes and hypercholesterolemia in a population-based sample of Japanese]
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Kazumasa, Yamagishi, Takako, Hosoda, Toshimi, Sairenchi, Kazui, Mori, Hiroshi, Tomita, Akio, Nishimura, Takeshi, Tanigawa, and Hiroyasu, Iso
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Adult ,Male ,Japan ,Risk Factors ,Hypercholesterolemia ,Hypertension ,Diabetes Mellitus ,Humans ,Female ,Middle Aged ,Aged ,Body Mass Index ,Follow-Up Studies - Abstract
To clarify relationships between BMI (body mass index) and the incidence of hypertension, diabetes and hypercholesterolemia among a community-based sample.A 4.3-year follow-up study was conducted of 1,427 men and women aged 40-69 to examine the relationships between BMI (kg/m2) and the incidence of hypertension, diabetes and hypercholesterolemia.During the follow-up, there were 118 cases of incident hypertension diagnosed, 56 of diabetes and 136 of hypercholesterolemia. After adjusting for sex, age, cognitive physical activity, food intake, alcohol intake, smoking, and blood pressure level, blood glucose level and serum total cholesterol level at the baseline, excess risks with the BMI category ofor = 27.0 versus 21.0-22.9 were found for hypertension [relative risk (95% CI) = 1.9(1.0-3.6)] and diabetes [2.9(1.2-7.4)]. However, no excess risk was evident for the 23.0-24.9 or 25.0-26.9 categories. Multivariate relative risks (95%CI) of hypercholesterolemia compared with the BMI category of 21.0-22.9 were 1.5 (0.9-2.6) for 23.0-24.9, 1.7(0.9-3.2) for 25.0-26.9 and 1.6 (0.8-3.1) foror = 27.0, none of which reached statistical significance. When we combined all three diseases, the relative risks (95%CI) compared with the BMI category of 21.0-22.9 were 0.9(0.6-1.5) for 23.0-24.9, 1.2(0.7-2.1) for 25.0-26.9 and 1.8 (1.0-3.3) foror = 27.0.Increased risks of hypertension, diabetes and lifestyle-related disease were only evident with the BMI categoryor = 27.0. Education for weight reduction should be less emphasized for persons with a BMI of 25.0-26.9 than for these with a value ofor = 27.0.
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- 2004
408. Prospective study of major and minor ST-T abnormalities and risk of stroke among Japanese
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Tetsuya Ohira, Akihiko Kitamura, Takeshi Tanigawa, Takashi Shimamoto, Yuko Nakagawa, Hiroyasu Iso, Minoru Iida, Yoshihiko Naito, Shinichi Sato, Tomoko Sankai, Hironori Imano, and Kazumasa Yamagishi
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Adult ,Male ,Risk ,Pediatrics ,medicine.medical_specialty ,Comorbidity ,Risk Assessment ,Electrocardiography ,Sex Factors ,Japan ,Predictive Value of Tests ,Risk Factors ,Medicine ,Humans ,Prospective Studies ,Prospective cohort study ,Stroke ,Aged ,Advanced and Specialized Nursing ,medicine.diagnostic_test ,Minnesota code ,business.industry ,Incidence (epidemiology) ,Ischemic strokes ,Incidence ,Arrhythmias, Cardiac ,Middle Aged ,medicine.disease ,Relative risk ,Multivariate Analysis ,Physical therapy ,Female ,Neurology (clinical) ,Cardiology and Cardiovascular Medicine ,business ,Cohort study ,Follow-Up Studies - Abstract
Background and Purpose— The association between minor ST-T abnormalities and stroke incidence has not been well elucidated. We sought to examine the relationship between nonspecific minor or major ST-T abnormalities and the incidence of stroke among Japanese men and women. Methods— A 15.4-year prospective study was conducted with 10 741 men and women aged 40 to 69 years in 4 Japanese communities. Electrocardiograms were taken at baseline and were read according to the Minnesota Code. The incidence of stroke was ascertained using systematic surveillance. Results— During the 15.4-year follow-up, 602 strokes (339 ischemic strokes, 129 intracerebral hemorrhages, 80 subarachnoid hemorrhages, and 54 unclassified strokes) occurred. Both men and women with major ST-T abnormalities had approximately 3-fold higher age-adjusted relative risk and 2-fold higher multivariate-adjusted relative risk of total stroke than did those without such abnormalities. Men with minor ST-T abnormalities had a 2.3-fold higher age-adjusted relative risk of total stroke, both ischemic and hemorrhagic, than did those without such abnormalities. After we adjusted further for hypertension category, the relative risk for minor ST-T abnormalities was reduced substantially but remained statistically significant: 1.8 (95% CI, 1.3 to 2.4) for total stroke, 1.9 (95%CI, 1.3 to 2.8) for ischemic stroke, and 1.7 (95% CI, 1.0 to 3.0) for hemorrhagic stroke. For women, however, there was no relation between minor ST-T abnormalities and stroke incidence. Conclusions— Minor ST-T abnormalities have predictive value for the risk of total stroke, both ischemic and hemorrhagic, among middle-aged Japanese men, as do major ST-T abnormalities for both sexes.
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- 2003
409. Association of lymphocyte sub-populations with clustered features of metabolic syndrome in middle-aged Japanese men
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Tetsuya Ohira, Takashi Shimamoto, Kazumasa Yamagishi, Noriyuki Kawamura, Isao Muraki, Hiroyasu Iso, Susumu Sakurai, Akinori Nakata, and Takeshi Tanigawa
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Adult ,Blood Glucose ,Male ,medicine.medical_specialty ,Cellular immunity ,Lymphocyte ,Sensitivity and Specificity ,Body Mass Index ,Cohort Studies ,chemistry.chemical_compound ,Japan ,Risk Factors ,T-Lymphocyte Subsets ,Internal medicine ,medicine ,Cluster Analysis ,Humans ,Lymphocyte Count ,Triglycerides ,Probability ,Metabolic Syndrome ,Triglyceride ,Vascular disease ,business.industry ,Cholesterol, HDL ,Blood Pressure Determination ,Middle Aged ,medicine.disease ,Endocrinology ,medicine.anatomical_structure ,Blood pressure ,chemistry ,Cardiovascular Diseases ,Metabolic syndrome ,Cardiology and Cardiovascular Medicine ,business ,Body mass index ,Biomarkers ,Lipoprotein - Abstract
To examine the relationship between altered cellular immune status and clustered features of the metabolic syndrome, we measured body mass index (BMI), serum concentrations of high-density lipoprotein-cholesterol, triglycerides, fasting plasma glucose, and blood pressure levels as well as differential leukocyte counts and lymphocyte sub-populations among 439 apparently healthy Japanese men aged 35-60 years. The components of the metabolic syndrome were defined based on the following criteria: BMI/=25.0 kg/m(2), fasting plasma glucose/=6.11 mmol/l, systolic blood pressure/=130 mmHg and/or diastolic blood pressure/=85 mmHg, high-density lipoprotein (HDL)-cholesterol1.03 mmol/l, and fasting triglyceride/=1.69 mmol/l. Counts of total leukocyte, total lymphocyte, CD3 + T cell, CD4 + T cell, and CD4 + CD45RO + T cell significantly correlated with the number of components of the metabolic syndrome (0, 1, 2, and 3+) after adjustment for age and smoking status. These findings were more evident among smokers than among non-smokers. The counts of total leukocytes, total lymphocytes and more specifically memory (CD4 + CD45RO + T) cells were elevated with clustered features of the metabolic syndrome in middle-aged men, which suggest the involvement of altered cellular immune status in the pathogenesis of atherosclerosis.
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- 2003
410. P2-302 Nocturnal intermittent hypoxia and cardiovascular risk factors in community-dwelling Japanese: the Circulatory Risk in Communities Study (CIRCS)
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Hiroyasu Iso, Takeshi Tanigawa, Hironori Imano, Kazumasa Yamagishi, S. Sato, T Ohira, Susumu Sakurai, Akihiko Kitamura, M Kiyama, and Isao Muraki
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medicine.medical_specialty ,Epidemiology ,Cross-sectional study ,business.industry ,Public Health, Environmental and Occupational Health ,Intermittent hypoxia ,Type 2 diabetes ,medicine.disease ,Endocrinology ,Internal medicine ,medicine ,Sleep study ,Metabolic syndrome ,business ,Prospective cohort study ,Cohort study - Abstract
Introduction To investigate whether nocturnal intermittent hypoxia (NIH), a surrogate marker for sleep apnoea, is associated with cardiovascular risk factors, we conducted epidemiological studies. Methods The CIRCS is a prospective cohort study across Japan since 1963 to examine risk factors for cardiovascular disease. Subjects aged 40–69 years were recruited to the sleep study in three communities. NIH was estimated by hourly occurrences of oxygen desaturation of ≥3% (3% oxygen desaturation index [3% ODI]) by a pulse-oximeter during a night9s sleep in the participant9s own home. We defined no, mild and moderate-to-severe NIH by 3% ODI as Results Compared with no NIH, the multivariable OR of hypertension was 1.63 (95% CI 1.1 to 2.5) for moderate-to-severe NIH. The prevalence of a high CRP (≥1.0 mg/l) was 1.4 to 1.7-fold higher for mild to severe NIH in both sexes. The multivariable ORs of metabolic syndrome was 3.2 (2.2 to 4.7) for moderate-to-severe NIH among men and 5.8 (3.4 to 9.8) among women, respectively. The multivariable-adjusted HRs of developing type 2 diabetes was 1.3 (0.9 to 1.8) among those with mild NIH and 1.7 (1.0 to 2.8) among those with moderate-to-severe NIH. Conclusion NIH was associated with hypertension, elevated serum CRP levels, the accumulation of metabolic risk factors, and increased risk of developing type 2 diabetes among middle-aged Japanese.
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- 2011
411. From the authors: Sleep apnoea in Asians and Caucasians: comparing apples and oranges
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Aaron R. Folsom, Takeshi Tanigawa, Hiroyasu Iso, Kazumasa Yamagishi, and A. Kitamura
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Pulmonary and Respiratory Medicine ,Pediatrics ,medicine.medical_specialty ,business.industry ,Breathing ,Medicine ,business ,Body mass index ,Sleep in non-human animals - Abstract
From the authors: We thank P.R. Genta and G. Lorenzi-Filho for their interest in and comments on our study [1]. One of our major findings was that the prevalence of sleep-disordered breathing (SDB) was similar among the community-based samples of Caucasians, Hispanics and Japanese within the same body mass index …
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- 2011
412. Type 2 Diabetes in Well-Controlled Hypertension
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David R. Jacobs, Hiroshi Yatsuya, and Kazumasa Yamagishi
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medicine.medical_specialty ,business.industry ,Internal medicine ,Hypertension complications ,MEDLINE ,Medicine ,General Medicine ,Type 2 diabetes ,Cardiology and Cardiovascular Medicine ,business ,medicine.disease - Published
- 2011
413. Maternal predictive factors for fetal congenital heart block in pregnant mothers positive for anti-SS-A antibodies.
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Hiroto Tsuboi, Takayuki Sumida, Hisashi Noma, Kazumasa Yamagishi, Ai Anami, Kotaro Fukushima, Hitoshi Horigome, Yasuki Maeno, Mitsumasa Kishimoto, Yoshinari Takasaki, Masahiro Nakayama, Masako Waguri, Haruhiko Sago, and Atsuko Murashima
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CONGENITAL heart disease ,PREGNANCY ,PREDNISOLONE ,CORTICOSTEROIDS ,IMMUNOGLOBULINS - Abstract
Objective: To determine the maternal predictive factors for fetal congenital heart block (CHB) in pregnancy in mothers positive for anti-SS-A antibodies. Methods: The Research Team for Surveillance of Autoantibody-Exposed Fetuses and Treatment of Neonatal Lupus Erythematosus, the Research Program of the Japan Ministry of Health, Labor and Welfare, performed a national survey on pregnancy of mothers positive for anti-SS-A antibodies. We analyzed 635 pregnant mothers who tested positive for anti-SS-A antibodies before conception but had no previous history of fetal CHB. We performed univariate and multivariate analysis (models 1, 2, and 3 using different set of independent variables) investigated the relation between risk of fetal CHB and maternal clinical features. Results: Of the 635 pregnant mothers, fetal CHB was detected in 16. Univariate analysis showed that fetal CHB associated with use of corticosteroids before conception (OR 3.72, p=0.04), and negatively with use of corticosteroids (equivalent doses of prednisolone (PSL), at -10 mg/day) after conception before 16-week gestation (OR 0.17, p=0.03). In multivariate analysis, model 1 identified the use of corticosteroids before conception (OR 4.28, p=0.04) and high titer of anti-SS-A antibodies (OR 3.58, p=0.02) as independent and significant risk factors, and model 3 identified use of corticosteroids (equivalent doses of PSL, at -10 mg/day) after conception before 16-week gestation as independent protective factor against the development of fetal CHB (OR 0.16, p=0.03). Other maternal clinical features did not influence the development of fetal CHB. Conclusion: The results identified high titers of anti-SS-A antibodies and use of corticosteroids before conception as independent risk factors, and use of corticosteroids (equivalent doses of PSL, at -10 mg/day) after conception before 16-week gestation as an independent protective factor for fetal CHB. [ABSTRACT FROM AUTHOR]
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- 2016
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414. Coping strategies and risk of cardiovascular disease incidence and mortality: the Japan Public Health Center-based prospective Study.
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Svensson, Thomas, Inoue, Manami, Sawada, Norie, Kazumasa Yamagishi, Charvat, Hadrien, Saito, Isao, Yoshihiro Kokubo, Hiroyasu Iso, Noriyuki Kawamura, Shibuya, Kenji, Mimura, Masaru, and Shoichiro Tsugane
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Aims Coping strategies may be significantly associated with health outcomes. This is the first study to investigate the association between baseline coping strategies and cardiovascular disease (CVD) incidence and mortality in a general population cohort. Methods and results The Japan Public Health Center-based prospective Study asked questions on coping in its third follow-up survey (2000-04). Analyses on CVD incidence and mortality included 57 017 subjects aged 50-79 without a history of CVD and who provided complete answers on approach- and avoidance-oriented coping behaviours and strategies. Cox regression models, adjusted for confounders, were used to determine hazard ratios (HRs) according to coping style. Mean follow-up time was 7.9 years for incidence and 8.0 years for mortality. The premorbid use of an approach-oriented coping strategy was inversely associated with incidence of stroke (HR ¼ 0.85; 95% CI, 0.73-1.00) and CVD mortality (HR ¼ 0.74; 95% CI, 0.55-0.99). Stroke subtype analyses revealed an inverse association between the approach-oriented coping strategy and incidence of ischaemic stroke (HR ¼ 0.79; 95% CI, 0.64-0.98) and a positive association between the combined coping strategy and incidence of intra-parenchymal haemorrhage (HR ¼ 2.03; 95% CI, 1.01-4.10). Utilizing an avoidance coping strategy was associated with increased mortality from ischaemic heart disease (IHD) only in hypertensive individuals (HR ¼ 3.46; 95% CI, 1.07-11.18). The coping behaviours fantasizing and positive reappraisal were associated with increased risk of CVD incidence (HR ¼ 1.24; 95% CI, 1.03-1.50) and reduced risk of IHD mortality (HR ¼ 0.63; 95% CI, 0.40-0.99), respectively. Conclusion An approach-oriented coping strategy, i.e. proactively dealing with sources of stress, may be associated with significantly reduced stroke incidence and CVD mortality in a Japanese population-based cohort. [ABSTRACT FROM AUTHOR]
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- 2016
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415. The relationship between sodium concentrations in spot urine and blood pressure increases: a prospective study of Japanese general population: the Circulatory Risk in Communities Study (CIRCS).
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Mitsumasa Umesawa, Kazumasa Yamagishi, Hiroyuki Noda, Ai Ikeda, Shinobu Sawachi, Isao Muraki, Choy-Lye Chei, Renzhe Cui, Masanori Nagao, Tetsuya Ohira, Tomoko Sankai, Takeshi Tanigawa, Akihiko Kitamura, Masahiko Kiyama, Hiroyasu Iso, Umesawa, Mitsumasa, Yamagishi, Kazumasa, Noda, Hiroyuki, Ikeda, Ai, and Sawachi, Shinobu
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URINALYSIS ,BLOOD pressure ,CROSS-sectional method ,SODIUM ,JAPANESE people ,LONGITUDINAL method ,HEALTH ,HYPERTENSION epidemiology ,BIOCHEMISTRY ,HYPERTENSION ,PHENOMENOLOGY ,OBESITY ,SALT ,URINARY organ physiology ,COMORBIDITY ,PREDICTIVE tests ,DIAGNOSIS - Abstract
Background: Although several cross-sectional and intervention studies showed that sodium intake or excretion was associated with blood pressure levels, no prospective study has examined the long-term association between sodium excretion in spot urine and blood pressure changes.Methods: We conducted a prospective study of 889 normotensive subjects (295 men and 594 women, mean age 57.3 years) who underwent the baseline survey including spot urine test in 2005 and the follow-up survey in 2009 to 2011 (mean follow-up period: 5.8 years). We examined the association between sodium concentration in spot urine, a validated index of sodium excretion occurring over 24-h, and blood pressure changes between baseline and follow-up survey in all, non-overweight (body mass index(BMI) ≤ 25 kg/m(2)) and overweight normotensives.Results: For all subjects, sodium concentrations in spot urine were not associated with either systolic or diastolic blood pressure changes. When stratified by BMI at baseline survey, sodium concentrations were positively associated with systolic blood pressure changes in non-overweight subjects, but not in overweight subjects. After adjustment for age, sex, BMI, alcohol intake status, current smoking and estimated glomerular filtration rate, the multivariable-adjusted mean values of the systolic blood pressure change among non-overweight subjects was +7.3 mmHg in the highest quartiles of sodium concentrations, while it was +3.9 mmHg in the lowest quartile (P for difference = 0.021, P for trend = 0.040). After further adjustment of baseline blood pressure levels, the association was slightly weakened; the multivariable-adjusted mean values of the systolic blood pressure changes were +7.0 mmHg and +4.2 mmHg (P for difference = 0.047, P for trend = 0.071).Conclusions: High sodium concentrations in spot urine were associated with subsequent systolic blood pressure increases among non-overweight normotensive individuals. (272 words). [ABSTRACT FROM AUTHOR]- Published
- 2016
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416. Trends in sudden cardiac death and its risk factors in Japan from 1981 to 2005: the Circulatory Risk in Communities Study (CIRCS)
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Hiroyuki Noda, Hironori Imano, Kazumasa Yamagishi, Minako Maruyama, Masahiko Kiyama, Takashi Shimamoto, Hiroyasu Iso, Tetsuya Ohira, Akihiko Kitamura, Yoshinori Ishikawa, Kenji Maeda, and Takeo Okada
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medicine.medical_specialty ,education.field_of_study ,Pediatrics ,Longitudinal study ,Epidemiology ,business.industry ,Research ,Public health ,Incidence (epidemiology) ,Population ,General Medicine ,medicine.disease ,Sudden cardiac death ,Diabetes mellitus ,Circulatory system ,medicine ,education ,business ,Demography - Abstract
Objective There is little evidence whether sudden cardiac death (SCD) is increasing in Asia, although the incidence of coronary heart disease among urban middle-aged Japanese men has increased recently. We examined trends in the incidence of SCD and its risk factors in the Circulatory Risk in Communities Study. Design and setting This was a population-based longitudinal study. Surveillance of men and women for SCD incidence and risk factors was conducted from 1981 to 2005. Subjects The surveyed population was all men and women aged 30–84 years who lived in three rural communities and one urban community in Japan. Main outcome measures Trends in SCD incidence and its risk factors. Results Age-adjusted and sex-adjusted incidence of SCD decreased from 1981–1985 to 1991–1995, and plateaued thereafter. The annual incidence per 100 000 person-years was 76.0 in 1981–1985, 57.9 in 1986–1990, 39.3 in 1991–1995, 31.6 in 1996–2000 and 36.8 in 2001–2005. The prevalence of hypertension decreased from 1981–1985 to 1991–1995, and plateaued thereafter for men and women. The age-adjusted prevalence of current smoking for men decreased while that of diabetes mellitus increased for both sexes from 1981–1985 to 2001–2005. Conclusions The incidence of SCD decreased from 1981 to 1995 but was unchanged from 1996 to 2005. Continuous surveillance is necessary to clarify future trends in SCD in Japan because of an increasing incidence of diabetes mellitus., Article summary Article focus The incidence of coronary heart disease among urban middle-aged Japanese men increased from the 1990s to the 2000s, therefore the incidence of sudden cardiac death (SCD) may have increased in recent decades. This is the first study to examine recent trends in SCD in Japan. Key messages The age-adjusted and sex-adjusted incidence of SCD among men and women aged 30–84 years in four Japanese communities decreased from 1981–1985 to 1991–1995 and plateaued after 1996. Continuous surveillance is necessary to clarify future trends in SCD in Japan because of an increasing incidence of diabetes mellitus. Strengths and limitations of this study Trends in SCD were analysed using population-based data from a large number of participants in a long-term observational study and annual cardiovascular risk factor surveys ascertained the trends in predisposing risk factors of SCD. The incidence of SCD was only examined for people aged 30–84 years; other age ranges were not included. Clinical features and neuroimaging reports were used to exclude death due to stroke; some cases may have been misclassified, especially out-of-hospital deaths.
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- 2012
417. P2-177 Accumulation of obesity-related eating behaviours and the incidence of type 2 diabetes among middle-aged Japanese men and women: the Circulatory Risk in Communities Study (CIRCS)
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M Kurokawa, T Ohira, Hiroyuki Noda, Y Ishikawa, Hironori Imano, Kazumasa Yamagishi, Akihiko Kitamura, Takeo Okada, K Maeda, M Nakamura, K Maruyama, Hiroyasu Iso, M Kiyama, S Nishimura, and S. Sato
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medicine.medical_specialty ,Longitudinal study ,Epidemiology ,Proportional hazards model ,business.industry ,Incidence (epidemiology) ,digestive, oral, and skin physiology ,Public Health, Environmental and Occupational Health ,Type 2 Diabetes Mellitus ,Type 2 diabetes ,medicine.disease ,Obesity ,Endocrinology ,Before Bedtime ,Internal medicine ,medicine ,Eating behaviour ,business ,Demography - Abstract
Introduction To examine whether the accumulation of obesity-related eating behaviours such as eating quickly, eating until full, eating right before bedtime and breakfast skipping are associated with incidence of type 2 diabetes mellitus (T2DM) among middle-aged Japanese men and women. Methods The 2840 subjects (890 men and 1950 women) who were aged 40–69 year and free of T2DM were enrolled at baseline survey from 2003 to 2006 in a community-based longitudinal study, the CIRCS. The subjects were asked following four eating behaviours by questionnaire at baseline: “speed of eating”, “eating until full”, “eating right before bedtime” and “breakfast skipping”. T2DM was defined as fasting serum glucose ≥7.0 mmol/l, non-fasting serum glucose ≥11.1 mmol/l or medication for T2DM. We followed up to March 2010, and calculated HR and 95% coefficient interval (95% CI) of T2DM by using Cox proportional hazard model after adjustment for potential risk factors. Results During 7-year follow-up period, 155 cases (70 men and 85 women) had an onset of T2DM. We calculated multivariate HR (95% CI) of T2DM for each number of eating behaviours among both men and women. Compared with persons without any eating behaviours, the multivariable HR (95% CI) of persons with 1, 2 and ≥3 of eating behaviours were 2.35 (1.06 to 5.19), 1.54 (0.65 to 3.63) and 3.24 (1.29 to 8.13), p for trend=0.09 in men and 0.92 (0.52 to 1.62), 0.67 (0.35 to 1.30) and 1.97 (0.92 to 4.22), p for trend=0.67 in women. Conclusion Our finding suggests that the accumulation of obesity-related eating behaviours raise the risk of T2DM for middle-aged Japanese men.
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- 2011
418. P2-226 Fish, vegetable, and fruit intakes and mortality from pulmonary embolism among Japanese men and women: the JACC (Japan Collaborative Cohort Study for Evaluation of Cancer Risk) study
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Akiko Tamakoshi, Hiroyasu Iso, Kazumasa Yamagishi, and T Ohira
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Gerontology ,medicine.medical_specialty ,Epidemiology ,Proportional hazards model ,business.industry ,Public Health, Environmental and Occupational Health ,medicine.disease ,Lower risk ,Pulmonary embolism ,Internal medicine ,Diabetes mellitus ,medicine ,%22">Fish ,Cancer risk ,business ,Body mass index ,Cohort study - Abstract
Introduction Numerous studies have reported associations of cardiovascular risk factors with pulmonary embolism (PE), but an association of dietary factors with the risk of PE is not fully established. Methods Using a prospective design, we studied the 14.7-year risk of PE death in relation to dietary factors, such as fish, vegetable, and fruit intakes, in 91 280 men and women aged 40–79 years in Japan. The HRs of PE death and 95% CIs were calculated by using the Cox proportional hazards model. Results We documented 56 deaths due to PE during 14.7 years. Mean values of age were significantly higher among participants with PE than those without PE, but there were no significant differences in body mass index (BMI), hypertension, or diabetes mellitus between participants with PE and those without PE. The age- and sex-adjusted HRs of PE were lower across frequency of fish intake. Compared with the participants in the lowest fish intake group ( Conclusion A greater fish intake is associated with a lower risk of PE death among Japanese men and women.
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- 2011
419. SP1-92 Serum -linolenic acid and disabling dementia among Japanese: the circulatory risk in communities study (CIRCS)
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T Ohira, Kazumasa Yamagishi, M Kiyama, Hiroyuki Noda, E Eguchi, Akihiko Kitamura, Y Ishikawa, Choy-Lye Chei, Ai Ikeda, and Hiroyasu Iso
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chemistry.chemical_classification ,medicine.medical_specialty ,Epidemiology ,business.industry ,Public Health, Environmental and Occupational Health ,Case-control study ,Fatty acid ,medicine.disease ,Gastroenterology ,Eicosapentaenoic acid ,Surgery ,chemistry ,Docosahexaenoic acid ,Diabetes mellitus ,Internal medicine ,medicine ,Dementia ,business ,Body mass index ,Polyunsaturated fatty acid - Abstract
Background Information on the impact of fatty acid composition on dementia has not yet been elucidated. Methods We performed a nested case-control study based on a cohort of approximately 12 000 Japanese people from two communities in the CIRCS, aged 45–85 at baseline (1984–1994). Fatty acid compositions were measured for 350 dementia cases and 700 controls (age, sex, community and baseline-year matched). The subjects were followed-up from 1999 through 2008, and incident disabling dementia was defined as dependent individuals who had moderate to severe dementia-related behavioural disturbance and/or cognitive impairment. This criterion was previously validated with 5-cog test (specificity 90%, positive predictive value 71%). The conditional OR and 95% CI for disabling dementia was calculated according to one SD increment of each fatty acid with adjustment for body mass index, smoking status, alcohol consumption, systolic blood pressure, antihypertensive medication use, serum total cholesterol and diabetes. Results Serum α-linolenic acids were inversely associated with disabling dementia (OR=0.82 [0.70–0.95] for 1-SD increment). No associations were observed for other fatty acids: OR=1.07 [0.91–1.26] for saturated fatty acids, 0.99 [0.84–1.17] for monounsaturated fatty acids, 0.98 [0.83–1.15] for n−6 polyunsaturated fatty acids, 1.00 [0.87–1.16] for eicosapentaenoic acid, and 1.03 [0.87–1.22] for docosahexaenoic acid. Conclusions We found a significant inverse association between serum α-linolenic acid and incident disabling dementia.
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- 2011
420. P2-178 The associations of dietary folate, vitamin B6 and B12 intakes with risk of sudden cardiac death: the Circulatory Risk in Communities Study (CIRCS)
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Akihiko Kitamura, Hironori Imano, Kazumasa Yamagishi, Takashi Shimamoto, Hiroyasu Iso, M Kiyama, Y Ishikawa, Takeo Okada, K Maeda, T Ohira, M Maruyama, and Hiroyuki Noda
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medicine.medical_specialty ,Epidemiology ,business.industry ,Confounding ,Public Health, Environmental and Occupational Health ,Case-control study ,medicine.disease ,Lower risk ,Surgery ,Sudden cardiac death ,Quartile ,Dietary folate ,Internal medicine ,Circulatory system ,medicine ,Vitamin b6 ,business - Abstract
Introduction To examine whether dietary folate, vitamin B 6 and B 12 intakes are associated with the risk of sudden cardiac death (SCD) among Japanese men and women. Method We conducted a nested case-control study. For each case of SCD entered between 1973 and 2001 in the CIRCS, two controls were randomly selected for each case and matched for age (±3 years), sex and community from among participants without history of SCD. The 77 cases and 154 controls aged 30–84 years were enrolled. Dietary folate, vitamin B 6 and B 12 intakes were assessed by 1 day 24 h dietary recall. We calculated conditional OR and 95% CI of each nutrients for risk of SCD adjusted for potential confounding factors. Result Higher intake of folate was associated with lower risk of SCD. The multivariable adjusted OR (95% CI) of highest quartile was 0.32 (95% CI 0.12 to 0.82), p for trend=0.06 compared with lowest quartile. However, vitamin B 6 and B 12 intakes were not associated with risk of SCD. The multivariable adjusted OR (95% CI) of highest quartile of vitamin B 6 and B 12 intakes were 1.25 (95% CI 0.49 to 3.21), p for trend=0.64 and 0.83 (95% CI 0.34 to 1.98), p for trend=0.86 compared with lowest quartiles, respectively. Conclusion Our findings suggest that higher dietary folate intake is associated with lower risk of SCD among Japanese men and women.
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- 2011
421. Response to 'Role of Pharmacists in the Management of Hypertensive Patients'
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Hiroyasu Iso, Hiroko Tobari, and Kazumasa Yamagishi
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medicine.medical_specialty ,business.industry ,Family medicine ,Internal Medicine ,Medicine ,business - Published
- 2011
422. Impact of Caregiver Type for 3-Year-Old Children on Subsequent Between-Meal Eating Habits and Being Overweight From Childhood to Adulthood: A 20-Year Follow-up of the Ibaraki Children's Cohort (IBACHIL) Study.
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Mizuki Sata, Kazumasa Yamagishi, Toshimi Sairenchi, Ai Ikeda, Fujiko Irie, Hiroshi Watanabe, Hiroyasu Iso, and Hitoshi Ota
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- 2015
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423. Association Between Average Daily Television Viewing Time and Chronic Obstructive Pulmonary Disease-Related Mortality: Findings From the Japan Collaborative Cohort Study.
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Shigekazu Ukawa, Akiko Tamakoshi, Hiroshi Yatsuya, Kazumasa Yamagishi, Masahiko Ando, and Hiroyasu Iso
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- 2015
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424. Hemoglobin A1c Levels and the Risk of Cardiovascular Disease in People Without Known Diabetes.
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Atsushi Goto, Mitsuhiko Noda, Yumi Matsushita, Maki Goto, Masayuki Kato, Akihiro Isogawa, Yoshihiko Takahashi, Kayo Kurotani, Shino Oba, Akiko Nanri, Tetsuya Mizoue, Kazumasa Yamagishi, Hiroshi Yatsuya, Isao Saito, Yoshihiro Kokubo, Norie Sawada, Manami Inoue, Hiroyasu Iso, Takashi Kadowaki, and Shoichiro Tsugane
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- 2015
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425. Prognostic impact of supraventricular premature complexes in community-based health checkups: The Ibaraki Prefectural Health Study.
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Nobuyuki Murakoshi, DongZhu Xu, Toshimi Sairenchi, Miyako Igarashi, Fujiko Irie, Takuji Tomizawa, Hiroshi Tada, Yukio Sekiguchi, Kazumasa Yamagishi, Hiroyasu Iso, Iwao Yamaguchi, Hitoshi Ota, and Kazutaka Aonuma
- Abstract
Aims The long-term prognosis of subjects with supraventricular premature complexes (SVPCs) remains unclear in the general population. The aim of this study was to examine the prognostic significance of SVPCs in community-based health checkups. Methods and results We assessed 63 197 individuals (mean age, 58.8±9.9 years; 67.6%women)whoparticipated in annual community-based health checkups in 1993 and were followed until 2008. The primary endpoint was stroke death, cardiovascular death (CVD), or all-cause death during a 14-year mean follow-up, and the secondary endpoint was first atrial fibrillation (AF) event in subjects without self-reported heart diseases or AF at baseline. Compared with subjects without SVPCs, the multivariate-adjusted hazard ratios (HRs) [95% confidence interval (CI)] of stroke death, CVD, and allcause death in subjects with SVPCs were 1.24 (0.98–1.56) for men and 1.63 (1.30–2.05) for women, 1.22 (1.04– 1.44) for men and 1.48 (1.25–1.74) for women, and 1.08 (0.99–1.18) for men and 1.21 (1.09–1.34) for women, respectively. Atrial fibrillation occurred in 386 subjects during the follow-up (1.05/1000 person-years). The presence of SVPCs at baseline was the significant predictor of AF onset [HRs (95% CI): 4.87 (3.61–6.57) for men and 3.87 (2.69–5.57) for women]. Propensity score matched analyses also revealed the presence of SVPCs was significantly associated with increased risks of AF incidence and CVD even after adjusting the potential confounders. Conclusion The presence of SVPCs in 12-lead electrocardiograms was a strong predictor of AF development, and associated with increased risk of CVD in general population. [ABSTRACT FROM AUTHOR]
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- 2015
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426. The Dose-Response Relationship Between Body Mass Index and the Risk of Incident Stage ≥3 Chronic Kidney Disease in a General Japanese Population: The Ibaraki Prefectural Health Study (IPHS).
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Takehiko Tsujimoto, Toshimi Sairenchi, Hiroyasu Iso, Fujiko Irie, Kazumasa Yamagishi, Hiroshi Watanabe, Kiyoji Tanaka, Takashi Muto, and Hitoshi Ota
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- 2014
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427. EUSI-ESO News
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Olle Lindvall, Shinji Nagahiro, J. Petersson, D. Inzitari, Thomas M. Glücker, R. Schmidt, A. Lindgren, Kazumasa Yamagishi, Zhong Pei, Takashi Fujieda, Anna Maria Fernàndez Planas, Anding Xu, A.J. Bastos-Leite, P. Scheltens, Stephen Meairs, G. Deuschl, C. Verny, Jari Koistinaho, T. Leoo, Nedka T. Chalakova, Brian Tomlinson, Yukiaki Miyagawa, Zhijian Liang, Takeshi Tanigawa, G. Marc, G. Neil Thomas, Jinsheng Zeng, C.C. Eschenfelder, Hiroyasu Iso, Martin E. Schwab, Bin Zhu, Martin Kretzschmar, Roxanna Liu, Nicolas Gaillard, Hiroshi Moriwaki, Masaaki Uno, F. Barkhof, E.W. Radü, Jennifer M. Lee, Yoshinori Ishikawa, Kazuo Minematsu, Wynnie W.M. Lam, Stephan G. Wetzel, Robert Côté, Ka Sing Wong, A. Koch, Xiang-Yan Chen, Britta Engelhardt, Sirun Liu, Borislav D. Dimitrov, Ulrich Dirnagl, Joann Porter, Y. Zhao, Denis Vivien, Juliana C.N. Chan, M von Arbin, Fang Wang, F. Dubas, W.M. van der Flier, E.C.W. van Straaten, R. Krug, Yoshinobu Ito, Akihiko Kitamura, Dimitri Renard, A.A. Gouw, Isao Muraki, Penka A. Atanassova, Shinichi Sato, Tadeusz Wieloch, Vincent T.F. Yeung, Cuimei Zhang, Matthias Endres, Shuhei Okazaki, Amy Y.X. Yu, U.M. Carl, Jian Wen Lin, Shunji Matsubara, Stephan Meckel, Markus Schwaninger, L. Pantoni, Takashi Shimamoto, T. Erkinjuntti, Hiroaki Naritomi, Christina Wolfson, Gelin Xu, A. Pasco, L.O. Wahlund, Li Ling, T. Herdegen, Koichi Satoh, J.K. Meyne, Katsutoshi Okada, Jay P. Mohr, F. Fazekas, Mark R. Keezer, Nancy J. Rothwell, C. Ryberg, A.F. Yusofi, Ryoma Morigaki, Klaus Scheffler, Siva P. Sontineni, and Xueying Ling
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Neurology ,business.industry ,Library science ,Medicine ,Neurology (clinical) ,Cardiology and Cardiovascular Medicine ,business - Published
- 2008
428. Daily Total Physical Activity and Incident Cardiovascular Disease in Japanese Men and Women: Japan Public Health Center-Based Prospective Study.
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Yasuhiko Kubota, Hiroyasu Iso, Kazumasa Yamagishi, Norie Sawada, Shoichiro Tsugane, Kubota, Yasuhiko, Iso, Hiroyasu, Yamagishi, Kazumasa, Sawada, Norie, Tsugane, Shoichiro, and JPHC Study Group (Japan Public Health Center)
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- 2017
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429. 1P-0087 Interaction of renin-angiotensin system genetic polymorphisms and sodium intake with blood pressure levels among a general population
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M. Kudo, Takashi Shimamoto, Kazumasa Yamagishi, Takeshi Tanigawa, Renzhe Cui, and Hiroyasu Iso
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medicine.medical_specialty ,education.field_of_study ,business.industry ,Population ,General Medicine ,Sodium intake ,Blood pressure ,Endocrinology ,Internal medicine ,Renin–angiotensin system ,Internal Medicine ,medicine ,Cardiology and Cardiovascular Medicine ,business ,education - Published
- 2003
430. XIIIth International Symposium on Atherosclerosis, September 28–October 2, 2003, Kyoto, Japan
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Y. Kumagai, Takashi Shimamoto, Jingbo Pi, N. Shimojo, Renzhe Cui, Takeshi Tanigawa, Hiroyasu Iso, and Kazumasa Yamagishi
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business.industry ,Immunology ,Internal Medicine ,Medicine ,Library science ,General Medicine ,Cardiology and Cardiovascular Medicine ,business - Published
- 2003
431. Rice consumption is not associated with risk of cardiovascular disease morbidity or mortality in Japanese men and women: a large population-based, prospective cohort study.
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Eshak, Ehab S., Hiroyasu Iso, Kazumasa Yamagishi, Yoshihiro Kokubo, Isao Saito, Hiroshi Yatsuya, Norie Sawada, Manami Inoue, and Shoichiro Tsugane
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MORTALITY ,CARDIOVASCULAR disease related mortality ,ANALYSIS of variance ,CARDIOVASCULAR diseases ,CHI-squared test ,CONFIDENCE intervals ,DISEASES ,INGESTION ,LONGITUDINAL method ,QUESTIONNAIRES ,RESEARCH funding ,RICE ,SELF-evaluation ,SURVEYS ,MATHEMATICAL variables ,BODY mass index ,DISEASE incidence ,DATA analysis software - Abstract
Background: Rice consumption has been associated with risk of type 2 diabetes, but its relation with cardiovascular disease (CVD) is limited. Objective: We examined the association between rice consumption and risk of CVD incidence and mortality in a Japanese population. Design: This was a prospective study in 91,223 Japanese men and women aged 40-69 y in whom rice consumption was determined and updated from 3 self-administered food-frequency questionnaires, each 5 y apart. Follow-up for incidence was from 1990 to 2009 in cohort I and 1993 to 2007 in cohort II and for mortality was from 1990 to 2009 in cohort I and 1993 to 2009 in cohort II. HRs and 95% CIs of CVD incidence and mortality were calculated according to quintiles of cumulative average rice consumption. Results: In 15-18 y of follow-up, we ascertained 4395 incident cases of stroke, 1088 incident cases of ischemic heart disease (IHD), and 2705 deaths from CVD. Rice consumption was not associated with risk of incident stroke or IHD; the multivariable HR (95% CI) in the highest compared with lowest rice consumption quintiles was 1.01 (0.90, 1.14) for total stroke and 1.08 (0.84, 1.38) for IHD. Similarly, there was no association between rice consumption and risk of mortality from CVD; the HR (95% CI) for mortality from total CVD was 0.97 (0.84, 1.13). There were no interactions with sex or effect modifications by body mass index for any endpoint. Conclusion: Rice consumption is not associated with risk of CVD morbidity or mortality. [ABSTRACT FROM AUTHOR]
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- 2014
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432. Association of Alcohol Consumption With Incident Hypertension Among Middle-Aged and Older Japanese Population.
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Yoshiro Okubo, Toshimi Sairenchi, Fujiko Irie, Kazumasa Yamagishi, Hiroyasu Iso, Hiroshi Watanabe, Takashi Muto, Kiyoji Tanaka, and Hitoshi Ota
- Abstract
The objective of this study was to examine the effect of age on the relationship between alcohol consumption and incident hypertension in a general Japanese population. A cohort of Japanese men (n=37 310) and women (n=78 426) aged 40 to 79 years who underwent community-based health checkups from 1993 to 2004 and were free of hypertension were followed up with annual examinations, including the measurement of blood pressure, until the end of 2010. Incident hypertension was defined as systolic blood pressure of ≥140 mmHg, diastolic blood pressure of ≥90 mmHg, or the initiation of treatment for hypertension. Hazard ratios for incident hypertension according to alcohol consumption were estimated using a Cox proportional hazards model adjusted for possible confounding variables. A total of 45 428 participants (39.3%) developed hypertension (16155 men and 29 273 women) for a mean follow-up time of 3.9 (1-18) years. Significant associations between alcohol consumption and incident hypertension were found in both sexes and age groups (P for trend was <0.001 for men aged 40-59 years and aged 60-79 years; 0.004 for women aged 40-59 years and 0.026 for women aged 60-79 years). No significant interaction with age on the association of alcohol consumption with incident hypertension was found in either sex (P for interaction, >0.05). Our results suggest that alcohol consumption is a similar risk factor for incident hypertension in both the middle-aged and the older populations. [ABSTRACT FROM AUTHOR]
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- 2014
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433. Body Mass Index and Weight Change During Adulthood Are Associated With Increased Mortality From Liver Cancer: The JACC Study.
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Yuanying Li, Hiroshi Yatsuya, Kazumasa Yamagishi, Kenji Wakai, Akiko Tamakoshi, and Hiroyasu Iso
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- 2013
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434. Soft drink intake in relation to incident ischemic heart disease, stroke, and stroke subtypes in Japanese men and women: the Japan Public Health Centre-based study cohort I.
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Eshak, Ehab S., Hiroyasu Iso, Yoshihiro Kokubo, Isao Saito, Kazumasa Yamagishi, Manami Inoue, and Shoichiro Tsugane
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JAPANESE people ,HEALTH ,STROKE risk factors ,CARBONATED beverages ,CARDIOVASCULAR diseases risk factors ,CONFIDENCE intervals ,LONGITUDINAL method ,MULTIVARIATE analysis ,RESEARCH funding ,SEX distribution ,PROPORTIONAL hazards models ,DATA analysis software ,DESCRIPTIVE statistics - Abstract
Background: Soft drink intake has been associated with obesity and diabetes, but its relation with risk of cardiovascular disease (CVD) is limited. Objective: We examined the association between soft drink intake and risk of CVD in a Japanese population. Design: This was a prospective study in 39,786 Japanese men and women aged 40-59 y in which soft drink intake was determined by using a self-administered food-frequency questionnaire. Follow-up was from 1990 to 2008. HRs and 95% CIs of incidence were calculated according to categories of soft drink intake. Results: During 18 y of follow-up, we ascertained 453 incident cases of ischemic heart disease (IHD) and 1922 cases of stroke, including 859 hemorrhagic and 1047 ischemic strokes. Soft drink intake was positively associated with risk of total stroke and more specifically ischemic stroke for women; the multivariable HR (95% CI) in the highest soft drink intake (almost every day) category compared with the lowest intake (never or rarely) category was 1.21 (0.88, 1.68; P-trend = 0.02) for total stroke and 1.83 (1.22, 2.75; P-trend = 0.001) for ischemic stroke. That association did not change significantly after the exclusion of early incident cases within 3-9 y from baseline. A nonsignificant inverse trend for risks of total and ischemic strokes was shown for men, and it was weakened after the exclusion of early incident cases or after the exclusion of participants with baseline comorbidities. Soft drink intake was not associated with risk of IHD or hemorrhagic stroke for either sex. Conclusion: Soft drink intake is associated with higher risk of ischemic stroke for women. [ABSTRACT FROM AUTHOR]
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- 2012
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435. Watching Television and Risk of Mortality From Pulmonary Embolism Among Japanese Men and Women: The JACC Study (Japan Collaborative Cohort).
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Toru Shirakawa, Hiroyasu Iso, Kazumasa Yamagishi, Hiroshi Yatsuya, Naohito Tanabe, Satoyo Ikehara, Shigekazu Ukawa, Akiko Tamakoshi, Shirakawa, Toru, Iso, Hiroyasu, Yamagishi, Kazumasa, Yatsuya, Hiroshi, Tanabe, Naohito, Ikehara, Satoyo, Ukawa, Shigekazu, and Tamakoshi, Akiko
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- 2016
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436. The relationships of proteinuria, serum creatinine, glomerular filtration rate with cardiovascular disease mortality in Japanese general population
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Yoshihiko Saito, Fujiko Irie, Toshimi Sairenchi, Nobuko Fukasawa, Maki Kanashiki, H. Ota, Kazumasa Yamagishi, Tadao Nose, Hiroyasu Iso, and S. Ikehara
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Male ,medicine.medical_specialty ,Population ,Renal function ,Blood Pressure ,urologic and male genital diseases ,Body Mass Index ,chemistry.chemical_compound ,Japan ,cardiovascular disease ,Cause of Death ,Internal medicine ,medicine ,Humans ,risk factors ,Risk factor ,Prospective cohort study ,education ,Antihypertensive Agents ,Cause of death ,education.field_of_study ,Creatinine ,glomerular filtration rate ,Proteinuria ,business.industry ,creatinine ,follow-up study ,Middle Aged ,medicine.disease ,mortality ,female genital diseases and pregnancy complications ,Endocrinology ,chemistry ,Cardiovascular Diseases ,Nephrology ,Female ,medicine.symptom ,proteinuria ,business ,Kidney disease - Abstract
Proteinuria, high serum creatinine, and reduced glomerular filtration rate (GFR) have been associated with increased mortality from cardiovascular disease (CVD) and all causes. However, the combined effect of proteinuria with serum creatinine and GFR on CVD or all-cause mortality has not been well investigated. We conducted a 10-year prospective cohort study of 30,764 men and 60,668 women aged 40-79 years who participated in annual health checkups in 1993. The Cox proportional hazards model was used to estimate the relative risk (RR) after adjusting for age, smoking, and other cardiovascular risk factors. The multivariable RR (95% confidence interval (CI)) of CVD death for positive vs negative proteinuria was 1.38 (1.05-1.79) among men and 2.15 (1.64-2.81) among women. The respective RR for the highest vs lowest creatinine groups (or = 1.3 vsor = 0.8 mg/dl for men andor = 1.1 vsor = 0.6 mg/dl for women) was 1.56 (1.19-2.04) among men and 2.15 (1.58-2.93) among women. The respective RR for GFR60 vsr = 100 ml/min/1.73 m2 was 1.65 (1.25-2.18) among men and 1.81 (1.39-2.36) among women. For individuals with proteinuria combined by hypercreatininemia or reduced GFR, the risk of CVD death was two-fold higher in men and 4-6-fold higher in women compared to those without proteinuria and with normal creatinine level or GFR. Similar associations were observed for stroke, coronary heart disease, and all-cause mortality. Proteinuria, and hypercreatininemia or reduced GFR and their combination were significant predictors of CVD and all-cause mortality.
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437. [Fish and omega-3 polyunsaturated fatty acids in relation to risk of cardiovascular disease]
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Kazumasa Yamagishi, Hori, M., and Iso, H.
438. [Body mass index and subsequent risk of hypertension, diabetes and hypercholesterolemia in a population-based sample of Japanese]
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Kazumasa Yamagishi, Hosoda T, Sairenchi T, Mori K, Tomita H, Nishimura A, Tanigawa T, and Iso H
439. Role of Polyunsaturated Fat in Modifying Cardiovascular Risk Associated With Family History of Cardiovascular Disease: Pooled De Novo Results From 15 Observational Studies.
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Laguzzi, Federica, Åkesson, Agneta, Marklund, Matti, Qian, Frank, Gigante, Bruna, Bartz, Traci M., Bassett, Julie K., Birukov, Anna, Campos, Hannia, Yoichiro Hirakawa, Fumiaki Imamura, Jäger, Susanne, Lankinen, Maria, Murphy, Rachel A., Senn, Mackenzie, Toshiko Tanaka, Tintle, Nathan, Virtanen, Jyrki K., Kazumasa Yamagishi, and Allison, Matthew
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FAMILY history (Medicine) , *CARDIOVASCULAR diseases risk factors , *UNSATURATED fatty acids , *SCIENTIFIC observation , *DOCOSAHEXAENOIC acid - Abstract
BACKGROUND: It is unknown whether dietary intake of polyunsaturated fatty acids (PUFA) modifies the cardiovascular disease (CVD) risk associated with a family history of CVD. We assessed interactions between biomarkers of low PUFA intake and a family history in relation to long-term CVD risk in a large consortium. METHODS: Blood and tissue PUFA data from 40 885 CVD-free adults were assessed. PUFA levels =25th percentile were considered to reflect low intake of linoleic, alpha-linolenic, and eicosapentaenoic/docosahexaenoic acids (EPA/DHA). Family history was defined as having =1 first-degree relative who experienced a CVD event. Relative risks with 95% CI of CVD were estimated using Cox regression and meta-analyzed. Interactions were assessed by analyzing product terms and calculating relative excess risk due to interaction. RESULTS: After multivariable adjustments, a significant interaction between low EPA/DHA and family history was observed (product term pooled RR, 1.09 [95% CI, 1.02-1.16]; P=0.01). The pooled relative risk of CVD associated with the combined exposure to low EPA/DHA, and family history was 1.41 (95% CI, 1.30-1.54), whereas it was 1.25 (95% CI, 1.16-1.33) for family history alone and 1.06 (95% CI, 0.98-1.14) for EPA/DHA alone, compared with those with neither exposure. The relative excess risk due to interaction results indicated no interactions. CONCLUSIONS: A significant interaction between biomarkers of low EPA/DHA intake, but not the other PUFA, and a family history was observed. This novel finding might suggest a need to emphasize the benefit of consuming oily fish for individuals with a family history of CVD. [ABSTRACT FROM AUTHOR]
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- 2024
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440. Daily Walking Time and Pneumonia Mortality Among Elderly With/Without Medical History of Myocardial Infarction or Stroke.
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Shigekazu Ukawa, Wenjing Zhao, Hiroshi Yatsuya, Kazumasa Yamagishi, Hiroyasu Iso, and Akiko Tamakoshi
- Published
- 2017
441. Insulin Resistance, Secretion and Risk of Incident Coronary Heart Disease in Non-diabetic Japanese Population: The Circulatory Risk in Communities Study.
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Hironori Imano, Akihiko Kitamura, Kazumasa Yamagishi, Masahiko Kiyama, Tetsuya Ohira, Renzhe Cui, Mitsumasa Umesawa, Takeo Okada, and Hiroyasu Iso
- Published
- 2014
442. Kidney Measures Beyond Conventional Risk Factors for Predicting Incident Cardiovascular Disease: A Collaborative MetaAnalysis of 16 Cohorts.
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Matsushita, Kunihiro, Coresh, Josef, Yingying Sang, Chalmers, John, Fox, Caroline, Ishani, Areef, Jafar, Tazeen, Jassal, Simerjot K., Landman, Gijs W., Muntner, Paul, Roderick, Paul, Sairenchi, Toshimi, Schöttker, Ben, Shankar, Anoop, Shlipak, Michael, Tonelli, Marcello, Townend, John, van Zuilen, Arjan, Kazumasa Yamagishi, and Kentaro Yamashita
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- 2014
443. Brief self-exercise education for adults with chronic knee pain: A randomized controlled trial.
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Hiroshige Jinnouchi, Akihiko Kitamura, Ko Matsudaira, Hironobu Kakihana, Hiroyuki Oka, Kazumasa Yamagishi, Masahiko Kiyama, and Hiroyasu Iso
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KNEE pain , *CHRONIC pain , *ADULT education , *RANDOMIZED controlled trials , *PAIN management - Abstract
Objectives: Effective brief instructions for self-management of chronic knee pain are needed. Methods: Forty-six participants with chronic knee pain were randomly allocated into two programmes: material-based education alone or brief self-exercise education (brief-See), which comprised a 100-minute instruction for self-exercise combined with compact pain education. Total function (KOOS4, 4-subscale average of knee injury and osteoarthritis outcome score), pain intensity (NRS, numeric rating scale), self-efficacy (PSEQ, pain self-efficacy questionnaire), and health-related quality of life (EQ-5D, European quality of life-5 dimensions) were evaluated at baseline and 4 and 12 weeks after the initial intervention. A generalized mixed linear model estimated average group differences in changes from baseline and 95% confidence intervals (95% CIs) using intention-to-treat principle. Results: Compared to material-based education alone, the brief-See provided significant additional improvements of 9.4% (95% CI: 2.3 to 16.4) on the KOOS4 and 5.4 points (0.3 to 10.4) on the PSEQ at 12 weeks but did not on the NRS and EQ-5D. Adherence and satisfaction were favourable in the brief-See without any notable adverse event. Conclusions: Adding the brief-See to material-based education could be more acceptable and restore total function and self-efficacy, which could contribute to the self-management of chronic knee pain in primary care. [ABSTRACT FROM AUTHOR]
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- 2023
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444. Alcohol consumption from midlife and risk of disabling dementia in a large population‐based cohort study in Japan.
- Author
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Yoko Shimizu, Norie Sawada, Hikaru Ihira, Sarah Krull Abe, Manami Inoue, Nobufumi Yasuda, Kazumasa Yamagishi, Motoki Iwasaki, and Shoichiro Tsugane
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DEMENTIA risk factors , *COMPLICATIONS of alcoholism , *JAPANESE people , *LIFESTYLES , *CONFIDENCE intervals , *PUBLIC health , *RISK assessment , *ALCOHOL drinking , *PSYCHOSOCIAL factors , *QUESTIONNAIRES , *DESCRIPTIVE statistics , *RESEARCH funding , *LONGITUDINAL method , *LONG-term health care , *INSURANCE , *PROPORTIONAL hazards models , *MEASUREMENT errors , *MIDDLE age - Abstract
Objectives: The association between alcohol consumption and dementia in Japanese is poorly understood, and use of single‐point alcohol assessment may cause measurement error. We explored this association in Japanese using repeated alcohol assessments. Methods: Participants in the Japan Public Health Center‐based Prospective Study (JPHC Study) since 1990 and who were alive in 2006 were followed from 2006 until 2016 for dementia ascertainment. Disabling dementia was identified through longterm care insurance records. Alcohol consumption was assessed at the 5‐year questionnaire survey (1995–1999) and drinking patterns were assessed on repeated follow‐up (2000–2003). We performed Cox proportional hazards models with age as the time‐scale with adjustment for various lifestyle factors and medical history using light consumption (<75 g ethanol/week, hereinafter “g”) as reference. Analysis considering death as a competing risk was also conducted. Results: Among 42,870 participants aged 54–84 years, 4802 cases of disabling dementia were newly diagnosed. Average years from alcohol assessment until dementia incidence was 14.9 years. Non‐drinkers and regular drinkers with ≥450 g at 5 years had adjusted HRs (95% CI) of 1.29 (1.12–1.47) and 1.34 (1.12–1.60). Patterns of long‐term abstinence, former drinking, and regular heavy weekly consumption of ≥450 g showed increased adjusted HRs of 1.61 (1.28–2.03), 2.54 (1.93– 3.35), and 1.96 (1.49–2.59), respectively. Competing risk analysis yielded similar results. Conclusions: In Japanese, non‐drinking and regular weekly consumption of ≥450 g from midlife were associated with high risk of disabling dementia compared with light drinking. [ABSTRACT FROM AUTHOR]
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- 2023
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445. Anemia and Reduced Kidney Function as Risk Factors for New Onset of Atrial Fibrillation (from the Ibaraki Prefectural Health Study).
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DongZhu Xu, Nobuyuki Murakoshi, Toshimi Sairenchi, Fujiko Irie, Miyako Igarashi, Akihiko Nogami, Takuji Tomizawa, Iwao Yamaguchi, Kazumasa Yamagishi, Hiroyasu Iso, Hitoshi Ota, and Kazutaka Aonuma
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ANEMIA , *KIDNEY disease risk factors , *ATRIAL fibrillation , *COHORT analysis , *KAPLAN-Meier estimator , *DISEASE risk factors - Abstract
Chronic kidney disease (CKD) is a potential independent risk factor for atrial fibrillation (AF). It remains unclear whether anemia is synergistically associated with increased risk of AF onset in subjects with CKD. We evaluated the association of kidney function, hemoglobin (Hb), and their combination with new-onset AF in a population-based cohort study. We conducted a 15-year prospective cohort study of 132,250 Japanese subjects aged 40 to 79 years who participated in annual health checkups from 1993. Kaplan-Meier survival analysis was used to compare freedom from new-onset AF between groups classified by estimated glomerular filtration rate grade, Hb grade, and their combination. Cox proportional hazard model analysis was used to estimate hazard ratios (HRs) for new-onset AF. During a 13.8-year mean follow-up period, 1,232 (0.93%) subjects with new-onset AF were identified. Lower estimated glomerular filtration rate and lower Hb grades were significantly associated with a higher incidence of new-onset AF. Multivariate HRs and 95% confidence intervals (CIs) of new-onset AF were 1.38 (1.21 to 1.56) for mild CKD group, 2.56 (2.09 to 3.13) for CKD group, and 1.50 (1.24 to 1.83) for anemia group. Borderline Hb level was not significantly associated with increased risk for new-onset AF (HR 1.07, CI 0.91 to 1.25, p=0.4284). In the model with interaction term between CKD and anemia, the risk was significantly higher (p = 0.0343 for the interaction) than that predicted by each factor independently. In conclusion, decreased kidney function and lower Hb level are associated with increased risk for new-onset AF, especially when both are present. [ABSTRACT FROM AUTHOR]
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- 2015
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446. Relation Between Body Mass Index and Dry Eye Disease: The Japan Public Health Center-Based Prospective Study for the Next Generation.
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Yamanishi R, Sawada N, Hanyuda A, Uchino M, Kawashima M, Yuki K, Tsubota K, Kato T, Saito I, Arima K, Mizukami S, Tanno K, Sakata K, Yamagishi K, Iso H, Yasuda N, Shimazu T, Yamaji T, Goto A, Inoue M, Iwasaki M, and Tsugane S
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- Body Mass Index, Cross-Sectional Studies, Female, Humans, Japan epidemiology, Male, Prevalence, Prospective Studies, Risk Factors, Surveys and Questionnaires, Dry Eye Syndromes diagnosis, Dry Eye Syndromes epidemiology, Public Health
- Abstract
Objective: To investigate the relation between body mass index (BMI) and dry eye disease (DED)., Methods: We conducted a cross-sectional questionnaire-based survey in 85,264 Japanese men and women aged 40 to 74 years who participated in the Japan Public Health Center-based Prospective Study for the Next Generation (JPHC-NEXT Study). Dry eye disease was defined as the presence of severe symptoms or clinical diagnosis. A multivariable logistic regression model was used to estimate the odds ratios (ORs) of DED associated with BMI and their two-sided 95% confidence intervals (CIs). We adjusted for age, cohort area, visual display terminal time, smoking status, alcohol intake, education status, income status, as well as history of hormone replacement therapy for women., Results: Prevalence of DED was 23.4% (n = 19,985; 6,289 men, 13,696 women). Higher BMI was correlated with a lower prevalence of DED in a dose-response fashion, with an adjusted OR of DED (95% CI) per 1 kg/m2 increment of BMI of 0.98 (95% CI: 0.97-0.99) for men and 0.97 (95% CI: 0.97-0.98) for women., Conclusions: This large population-based study showed an inverse relationship between BMI and prevalence of DED in a Japanese population. Underestimation of DED is warned, especially for participants with high BMI., Competing Interests: The authors have no funding or conflicts of interest to disclose., (Copyright © 2021 Contact Lens Association of Ophthalmologists.)
- Published
- 2021
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