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Background: Despite substantial declines in underage drinking and binge drinking, alcohol consumption has increased in the past 30 years. This study examined how beverage‐specific drinking patterns varied by sex, age, and race and ethnicity from 1979 to 2020. Methods: Secondary data analysis was conducted on pooled data from the National Alcohol Survey series from 1979 to 2020 of a sample of U.S. adults ages 18 years or older. Total and beverage‐specific volume were calculated from graduated frequency questions on reported beverage type, which included beer, wine, and spirits. Sex‐stratified analyses focused on descriptive trends of each alcohol measure over time and by age and race and ethnicity. Time‐varying effect models were also conducted to identify subgroups at higher risk for increased consumption over time. Results: Women's drinking increased, with alcohol volume rising substantially from 2000 to 2020; the largest increase was among women 30 and older. Men's alcohol volume also rose over this period but remained below the levels of 1979 and 1984, with older adults increasing their consumption those 18–29 decreased their drinking. Beverage‐specific trends showed some similarities by gender: in 2020, wine volume was at its highest level for both women and men, while spirits volume also was at its highest level for men and in women was tied with the 1979 peak in spirits consumption. Increases were also found among Black men and women and Latina women from 2000 to 2020. Conclusions: Given the increases in alcohol volume, particularly among women and older age groups, alcohol policy, interventions, and education should consider ways to reduce harms associated with alcohol use among these groups. Continued monitoring of beverage‐specific drinking patterns is needed to track policy‐relevant changes. [ABSTRACT FROM AUTHOR]

Aims Sweeping policy changes during the COVID-19 pandemic increased alcohol availability through permitted to-go sales, potentially posing unique risks to college students. While to-go sales may make binge drinking more convenient, little remains known about these practices. Therefore, this study aimed to assess whether drinking establishments' to-go sales practices are associated with their other operational practices and state policy. Method This cross-sectional analysis included 221 randomly selected bars, nightclubs, and restaurants within two miles of a large public university. Telephone interviews assessed establishment practices, and the Alcohol Policy Information System provided state alcohol to-go laws. Regression models tested whether establishment to-go sales practices were associated with their business practices (logistic regression) and state policy (generalized estimating equations). Results Nearly one-half (44.8%) of drinking establishments sold alcohol to-go. Establishments with higher vodka prices had nearly 30% higher odds of selling spirits to-go (aOR  = 1.29) and establishments offering happy hours specials had more than twice the odds of selling beer (aOR  = 2.22), wine (aOR  = 2.53), and spirits to-go (aOR  = 2.60). Additionally, establishments that implemented physical distance requirements had higher odds of selling wine to-go (aOR  = 3.00). State to-go laws were associated with higher odds of selling wine (aOR  = 3.99) and spirits to-go (aOR  = 5.43) in the full sample and beer to-go (aOR  = 4.92) in urban counties. Conclusions Establishments that sell alcohol to-go tend to engage in other practices designed to drive sales. Evaluations of alcohol to-go sales laws on risky consumption among priority populations, including college students, are urgently needed to inform decisions about how to appropriately regulate sales. [ABSTRACT FROM AUTHOR]

Objective: "Wine-mom" culture, which promotes the idea that women should use alcohol to cope with the stressors of parenting, is pervasive in modern society, yet remains an under-researched variable in the context of women's alcohol use. The present investigation was a descriptive study and cross-cultural exploration (United States vs. United Kingdom) of the association between wine-mom culture (perceptions of wine-mom culture and related behaviors) and various alcohol-related outcomes, parenting experiences, and drinking motives. Methods: This study included 233 American and 233 British mothers recruited through Prolific. Participants completed the study questions/questionnaires in Qualtrics; they completed nine items measuring their perceptions of and engagement with wine-mom culture, the Alcohol Use Disorders Identification Test, the Parental Stress Scale, and the Drinking Motives Questionnaire-Revised, along with questions about their alcohol use and parenting experiences. Results: Our results indicated that although American mothers were more familiar with wine-mom culture than British mothers, the correlations observed were similar for both groups. Some of the wine-mom culture variables were associated with problematic alcohol use and parenting stress. Additionally, wine-mom culture-related behaviors had moderate to strong positive correlations with drinking to cope motives. Conclusion: Our findings suggest that future research should examine the role of wine-mom culture in the perception that alcohol can—or should—be used as a form of self-medication. Other future directions and considerations for this area of study are discussed. [ABSTRACT FROM AUTHOR]

This article examines the creation of product categories as a cultural construct. Categories serve not simply to classify different products but also to signify one's taste. To examine how categories became embedded with cultural meanings, this article takes an interdisciplinary approach: the narrative analysis which has been employed by a number of business historians and the production of culture perspective used in sociology. By using the case of the U.S. wine industry during the 1960s and 1970s, the article analyzes how the six facets proposed in the production of culture perspective – regulation, industry structure, organizational structure, occupational careers, technology, and markets – both constrained and promoted the constitution of a wine category and its dissemination. It argues that these two analytical frameworks help delineate the working of business practices in the dynamics of cultural systems without reducing culture or business to a static structure. [ABSTRACT FROM AUTHOR]

The COVID-19 pandemic itself constitutes an environment for people to experience the potential loss of control and freedom due to social distancing measures and other government orders. Variety-seeking has been treated as a mechanism to regain a sense of self-control. Using Machine Learning model and household-level data with a focus on the wine market in the United States, this study showcases the changing variety-seeking behavior over the pandemic year of 2020, in which people's perception of the status of restriction measures influences the degree of their use of variety-seeking behavior as a coping strategy. It is the shopping pattern and store environments that drive the behavioral responses in wine purchases to freedom-limited circumstances. Coupon use is associated with a lower variety-seeking tendency at the beginning of the stay-at-home order, but the variety level resumes when more time has passed in the restriction periods. Variety-seeking tendency increases with shopping frequency at the beginning of the social distancing measure but decreases to a level lower than all the non-restriction periods. [ABSTRACT FROM AUTHOR]

This paper investigates the relative importance of various attributes, including varietal, brands, and geographic origin, in explaining retail wine prices for the United States market. We use a metric based on the Shapely value, from cooperative game theory, in the context of an empirical hedonic price equation estimated using a large sample of retail wine sales for home consumption over the period 2007–2019. We find that brands alone explain more than 70% of the variation in wine prices, but geographic origin and varietals retain additional explanatory power. Furthermore, information about the geographic origin appears to be a considerably more important attribute than varietals. [ABSTRACT FROM AUTHOR]

We use data from Wine Spectator on 266,301 bottles from 12 countries sold in the United States to investigate the link between the score awarded by the guide and the price charged. The link between quality and price is positive, in line with the literature. In a deeper inspection, however, hedonic regressions show that the price premium attached to higher quality is significant only for "superstar" wines with more than 90 points (on a 50–100 scale), while prices of wines between 50 and 90 points are not statistically different from each other. Furthermore, an analysis performed through normal heteroskedastic and quantile regression models shows that the dispersion of quality-adjusted prices is described by an asymmetric U-shaped function of the score; that is, products with the lowest and highest quality have the highest residual standard deviation. Pursuing excellence is a risky strategy; the average price is significantly higher only for wines that achieve top scores, and the price premium becomes more volatile. [ABSTRACT FROM AUTHOR]

Purpose: Dietary intake is a primary source of cadmium (Cd) exposure in the non-smoking population. Plant foods containing metal-binding plant compounds such as polyphenols, phytates, and phytochelatins may reduce Cd bioavailability and result in lower Cd body burden. In this study, we investigated the association between plant food intake and urinary creatinine-adjusted Cd (uCd), a well-established marker of Cd body burden. Methods: Participants were from a cross-sectional sample of 1901 adults in the REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort. Dietary intake was assessed with a food frequency questionnaire. We created a 12-point plant food score (PFS) based on reported intake across seven categories (fruits, vegetables, legumes, nuts/seeds, whole grains, tea, and wine). Higher scores indicated higher consumption and diversity of plant food intake. Multivariable linear regression models were used to estimate the association between PFS and uCd. Due to the influence of age and smoking on Cd status, stratified analyses were conducted. Results: Mean PFS was 5.4 (SD 2.2) and mean uCd was 0.53 µg/g creatinine (SD 0.39). In adjusted models, PFS was not associated with uCd (p > 0.05). In stratified analyses, PFS was inversely associated with uCd (p = 0.047) with a 1-point higher PFS associated with 0.018 µg/g lower uCd among middle-aged (45–59) adults. No significant association was observed between PFS and uCd in older (≥ 60) adults. The association of PFS and uCd did not differ by smoking status. Conclusion: Our findings suggest higher plant food intake is associated with lower Cd body burden in middle-aged but not older adults. [ABSTRACT FROM AUTHOR]

The wine industry impacts the environment due to its massive scale of production, distribution, and retail. Wine retailers' green purchasing is essential for changing environmental initiatives because purchasing is a key function for managing an upstream supply chain and to further achieve sustainability throughout the entire supply chain. Thus, this study was designed to identify important drivers of wine retailers' green purchasing by incorporating both individual factors (values and competences) and organizational culture. Hierarchical linear modeling was employed to analyze the nested data obtained from 457 purchasing managers working for 10 wine retail companies in the United States. Results documented that individual values (social desire and moral attitudes), cognitive competence, and organizational culture such as the ethical behavior of top management, positively and directly influenced wine retailers' green purchasing behavior. In addition, the study findings revealed that the effects of individual values and cognitive competence on wine retailers' green purchasing behavior were positively enhanced when organizational culture was formed based on top management's ethical behavior, codes of conduct and incentives. Implications for developing effective methods for improving wine retailers' green purchasing behavior are presented and discussed. [ABSTRACT FROM AUTHOR]

The purpose of this research was to investigate Mid-Atlantic USA wine consumers' preferences for front wine label attributes for a lesser-known/unknown local wine variety. The wine consumer base in this part of the USA exceeds that of California. Although the mid-Atlantic is experiencing an increase in the number of wineries, there is a lack of region-specific consumer research that could be the basis for marketing strategies that may differ from those in more established wine regions, such as CA. We recruited 1011 mid-Atlantic consumers who drank wine (at least 1-/month) to view variations of a wine label, differing in wine tag, location description, font types, and images in a choice-based conjoint experiment. A greater percentage of consumers selected the "White Wine" tag and scripted fonts than the other options, with a generalized county text ("Proudly produced in Lehigh County, PA") being selected by more participants than the American Viticultural Area (AVA) ("Lehigh Valley AVA") or state ("Pennsylvania") texts; however, the location text had a lower importance than the wine tag variable. This study implies that a generalized county text that describes a more specific location where the grapes were grown may be more favorable to mid-Atlantic consumers in comparison to AVA or state texts, and that traditional images and generic wine labels are more preferable than wine labels they have not seen before and more contemporary label styles. Wineries in the mid-Atlantic region may want to add generalized county texts to their labels to appeal to the regional audience. As AVAs are used to promote specific wine regions in the USA, and only some consumers choose wines based on these designations, governments and marketing organizations may want to increase education on local AVAs to increase consumer awareness and interest. In addition, consumer differences in variety-seeking behavior and subjective as well as objective wine knowledge, but not attitudes toward locally produced foods, affected wine label choice: Consumers scoring higher in variety-seeking and wine knowledge preferred the specific wine varietal over the generic wine tag; similarly, consumers that indicated familiarity with the wine varietal also preferred the specific wine tag over the generic label. Differences in consumer psychographics appear to modulate front wine label preferences. [ABSTRACT FROM AUTHOR]

This study unpacks the relationship between engaging in entrepreneurial marketing practices and firm performance under the moderating role of competitive intensity, in an immediate post-crisis (COVID-19) period. Following 20 field interviews, the model testing stage featured survey responses from owner-managers of 306 small, rural wine producers across multiple regions in the United States. Underpinned by a relational, stakeholder perspective of resource-based theory, alongside an outside-in lens, unique insights revealed that in aggregate terms, entrepreneurial marketing activities were positively and significantly associated with firm performance, while competitive intensity yielded a non-significant moderating effect. Importantly, a post-hoc test revealed that only certain dimensions of the multi-faceted entrepreneurial marketing construct were significantly associated with firm performance, whereby, competitive intensity played different moderating roles (exhibiting varying interaction effects). Implications arise for practitioners building resilience after an environmental shock, whereby, they are likely to need to pivot strategies while facing new degrees of competitive intensity. • Combined entrepreneurial and market-oriented practices are likely to enhance performance when rural businesses face a crisis. • Owner-managers should implement strategies that enable them to withstand competitive intensity when pivoting business models. • Collaboration with appropriate partners may reduce opportunistic/dark-side activities among rivals across target markets. • Strategic flexibility, agility, and an ability to improvise are important capabilities in the event of a crisis. [ABSTRACT FROM AUTHOR]

"Wine mom" discourse encourages American women to self‐deprecatingly bond over the stressors of parenting and touts alcohol use as necessary means for coping and escapism. Before the added stress of the COVID‐19 pandemic, whereby alcohol sales and consumption increased in the United States, rates of heavy drinking and alcohol‐related illnesses among US women have been steadily increasing. Exceeding the clinical markers of responsible alcohol use, "wine mom" discourse normalizes an inextricable link between alcohol misuse and expectations of (White, middle‐class) motherhood. Online communities and businesses emphasize "wine mom" discourse for self‐acceptance and bonding in response to the impossible demands of hegemonic motherhood. In this critique of "wine mom" discourse, we argue that although alcohol consumption is commonly touted as self‐care, this messaging operates in toxic ways that harms women and reinforces patriarchy. Applying Merton's strain theory, we argue that "wine mom" trends and related discourse encompass a harmful form of conformity, if not false resistance, to the strain of flawed cultural goals and lacking institutionalized supports for American mothers. We call for true rebellion, emphasizing positive discourse as well as structural changes and policy reforms to dismantle patriarchal barriers and hegemonic motherhood constraints to better support American families. [ABSTRACT FROM AUTHOR]

Background: Underage binge drinking is a serious health concern that is likely influenced by the neighbourhood environment. However, longitudinal evidence has been limited and few studies have examined time-varying neighbourhood factors and demographic subgroup variation.Methods: We investigated neighbourhood influences and binge drinking in a national cohort of US 10th grade students at four times (2010-2014; n = 2745). We estimated odds ratios (OR) for past 30-day binge drinking associated with neighbourhood disadvantage, personal and property crime (quartiles), and number of liquor, beer and wine stores within 5 km, and then evaluated whether neighbourhood associations differ by age, sex and race/ethnicity.Results: Neighbourhood disadvantage was associated with binge drinking before 18 [OR = 1.54; 95% confidence interval (1.14, 2.08)], but not after 18 years of age. Property crime in neighbourhoods was associated with a higher odds of binge drinking [OR = 1.54 (0.96, 2.45)], an association that was stronger in early adulthood [4th vs 1st quartile: OR = 1.77 (1.04, 3.03)] and among Whites [4th vs 1st quartile: OR = 2.46 (1.03, 5.90)]. Higher density of liquor stores predicted binge drinking among Blacks [1-10 stores vs none: OR = 4.31 (1.50, 12.36)] whereas higher density of beer/wine stores predicted binge drinking among Whites [one vs none for beer: OR = 2.21 (1.06, 4.60); for wine: OR = 2.04 (1.04, 4.03)].Conclusions: Neighbourhood conditions, particularly those related to economic circumstances, crime and alcohol outlet density, were related to binge drinking among young adults, but associations varied across age and individual characteristics. [ABSTRACT FROM AUTHOR]

Background Although a number of studies have examined the association between alcohol intake and hip fractures, few have considered specific alcoholic beverages separately. Objectives We prospectively assessed total alcohol and specific alcoholic beverage consumption and risk of hip fractures in US men and women. Methods Health, lifestyle information, and hip fractures were self-reported on biennial questionnaires between 1980 and 2014 in 75,180 postmenopausal women from the Nurses' Health Study, and between 1986 and 2014 in 38,398 men aged ≥50 y from the Health Professionals Follow-Up Study. Diet was assessed approximately every 4 y with a semiquantitative FFQ. RRs were computed for hip fracture using Cox proportional hazards models, adjusting for potential confounders. Results We ascertained 2360 incident low trauma hip fractures in women and 709 in men. Among women, RRs for low trauma hip fractures compared with nondrinkers were 0.89 (95% CI: 0.80, 0.99) for an average daily consumption of <5.0 g, 0.81 (95% CI: 0.70, 0.94) for 5.0 to <10.0 g, 0.83 (95% CI: 0.71, 0.96) for 10.0 to <20.0 g, and 0.93 (95% CI: 0.78, 1.10) for ≥20.0 g. Among men, risk declined linearly with higher alcohol consumption (P -trend = 0.002). Multivariable RR compared with nondrinkers was 0.77 (95% CI: 0.59, 1.01), 0.69 (0.49, 0.96), and 0.67 (0.48, 0.95) for an average intake of 10 g/d to <20 g/d, 20 g/d to <30 g/d, and 30.0 g/d or more, respectively. In women, the alcoholic beverage most significantly associated with hip fracture risk was red wine (RR per serving = 0.59; 95% CI: 0.45, 0.79). In men, there was no clear association with specific alcoholic beverages. Conclusion In these 2 US cohorts, low to moderate alcohol consumption, when compared with no consumption, was associated with a lower risk of hip fractures, particularly with red wine consumption among women. [ABSTRACT FROM AUTHOR]

Winery owners in the Midwestern states of the United States have been working with each other and their state industry experts to improve the quality of their wines while also struggling to establish state and, at times, regional identities and overcome a widely-held perception that good wine is not made and cannot be made in the region. Drawing on a qualitative sociological study conducted over five years in Ohio, Indiana, Illinois, and Iowa, this article examines the issues with which winery owners and industry specialists have worked to improve quality and establish marketable identities. Challenges include the sourcing of quality grapes, the status of hybrid grapes, the skill-level of winemakers, and the desire to meet demand and please a wide range of customer preferences. Industry efforts to address these challenges are highlighted. [ABSTRACT FROM AUTHOR]

Background: Recent increases in alcohol‐related morbidity and mortality have not occurred alongside notable increases in per capita alcohol consumption (PCC). This discrepancy may be partially due to U.S. PCC estimates not including annual estimates of the percentage of alcohol by volume (%ABV) of beer, wine, and spirits, but rather relying on time‐invariant %ABV values. Methods: Building on a prior study covering 1950 to 2002, estimates of the annual mean %ABV of beer, wine, and spirits sold in the United States were calculated using the %ABV of major brands and sales of each beverage type for each state and nationally for the period 2003 to 2016. We applied these estimates to the calculation of annual beverage‐specific and total PCC, and made descriptive comparisons between our PCC estimates and those estimates using invariant %ABV values. Results: For all beverage types, our mean %ABV estimates increased nationally and for all but 5 states. The PCC estimates from wine and spirits utilizing variable %ABV values were lower than estimates using invariant %ABV, and consumption from beer was higher. Our total PCC estimates were also lower than %ABV‐invariant estimates; however, the percent change for %ABV‐invariant estimates was 5.8% compared to a 7.9% change in our %ABV‐variant estimates over the 2003 to 2016 period. Conclusions: Given the application of PCC estimates to understand changes in alcohol‐related morbidity and mortality, the inclusion of annual estimates of the %ABV of alcoholic beverages sold in the United States is necessary to ensure the precision of PCC measures such that the conclusions drawn from these applications are accurate and valid. We estimated and applied annual mean % alcohol by volume (ABV) values to calculations of beverage‐specific and total per capita alcohol consumption (PCC) for 2003‐2016 for all states and nationally. For all beverage types, our mean %ABV estimates increased nationally and for all but five states. Our total PCC estimates were lower than %ABV‐invariant estimates, however, the percent change was greater for %ABV‐variant estimates compared with %ABV‐invariant estimates. [ABSTRACT FROM AUTHOR]

Winery owners in the Midwestern states of the United States have been working with each other and their state industry experts to improve the quality of their wines while also struggling to establish state and, at times, regional identities and overcome a widely-held perception that good wine is not made and cannot be made in the region. Drawing on a qualitative sociological study conducted over five years in Ohio, Indiana, Illinois, and Iowa, this article examines the issues with which winery owners and industry specialists have worked to improve quality and establish marketable identities. Challenges include the sourcing of quality grapes, the status of hybrid grapes, the skill-level of winemakers, and the desire to meet demand and please a wide range of customer preferences. Industry efforts to address these challenges are highlighted. [ABSTRACT FROM AUTHOR]

This paper identifies a cost-minimizing tactic for U.S. wineries when buying French oak barrels. An otherwise trivial decision is potentially confounded by wineries' order timing choice and exchange rate risk. Using an intuitive model, which applies exchange rate futures prices and sixteen years of price data for a specific custom-made French oak barrel, we provide a general decision rule. The simple strategy of taking the early order discount dominates all alternative strategies and would have saved wineries nearly $78,000 compared to the more traditional ordering timeframe. Interestingly, using futures market prices does not improve the cost savings. [ABSTRACT FROM AUTHOR]

The standard gravity model is adapted to determine and quantify factors which influence EU wine exports to the United States. Using the trade intensity index to represent a country's relative share of the U.S. wine market, independent variables are chosen to augment the standard gravity model and identify the effects of transaction costs and productivity on the competitiveness of EU wine exports. Variables considered in the model include factors which represent a country's capacity to trade and those that represent their cost of trade. Factors that influence a country's capacity to trade include gross domestic product and relative per capita wine productivity; factors which influence cost to trade include distance between countries, import tariffs, and dummy variables related to trade agreements and whether the country is landlocked. Each of these factors is analyzed to determine how it affects the trade intensity. The positive GDP coefficient indicates the existence of intra-industry trade and suggests that the protection of Designations of Origin and Geographical Indications will help maintain EU wine exports. This analysis provides information that will enable producers and policy makers to better evaluate potential trade agreements and other strategies that influence the competitiveness of European wine in the world market. [ABSTRACT FROM AUTHOR]

Culturally modified red pine (Pinus resinosa) can be added to the long list of natural and artificial features that comprise the cultural landscape of the Boundary Waters Canoe Area Wilderness of Minnesota, U.S.A. This study provides historical context for the first cultural-modification dates derived from the dendrochronological evaluation of primary-growth, fire-killed red pine in the Border Lakes region. The tree-ring-based data are interpreted in the context of archaeological records, fur-trade era travel accounts, and ethnographic information to shed new light on the economy of the Border Lakes Ojibwe from the late 1700s to the early 1900s. Multiple lines of evidence from Lake Saganaga suggest that these culturally modified red pine were intentionally wounded in order to extract pitch, which was used to make the gum critical for constructing and repairing birch-bark canoes. Culturally modified red pine are a tangible artifact class that may serve to reframe modern perspectives on the critical role of the birch-bark canoe for transport in the historical Border Lakes landscape. These trees are living symbols of historical land-use patterns and are indicative of the strategic geography of the fur trade. [ABSTRACT FROM AUTHOR]

A large body of research data suggests that traditional dietary habits and lifestyle unique to the Mediterranean region (Mediterranean diet, MD) lower the incidence of chronic diseases and improve longevity. These data contrast with troubling statistics in the United States and other high income countries pointing to an increase in the incidence of chronic diseases and the projected explosion in cost of medical care associated with an aging population. In 2013, the MD was inscribed by UNESCO in the "Representative List of the Intangible Cultural Heritage of Humanity." The 2015-2020 Dietary Guidelines for Americans included the MD as a healthy dietary pattern. Therefore, specific objectives of this article are to provide an overview of the nutritional basis of this healthful diet, its metabolic benefits, and its role in multiple aspects of disease prevention and healthy aging. Whereas recommendations about the MD often focus on specific foods or bioactive compounds, we suggest that the eating pattern as a whole likely contributes to the health promoting effects of the MD. [ABSTRACT FROM AUTHOR]

Objective: Moderate alcohol consumption has antiinflammatory properties and is associated with reduced cardiovascular disease and rheumatoid arthritis risks. We investigated the association between alcohol consumption and systemic lupus erythematosus (SLE) risk among women followed in the Nurses' Health Study (NHS) cohorts.Methods: We conducted a prospective cohort analysis among 204,055 women in NHS (1980-2012) and NHSII (1989-2011) who were free of connective tissue disease and provided alcohol information at baseline. Alcohol consumption was assessed using a semiquantitative food frequency questionnaire every 2-4 years. We validated incident SLE through medical record review after self-report. Cox proportional hazards models estimated hazard ratios (HRs) for SLE based on cumulative average alcohol intake, adjusting for potential confounders. Results were meta-analyzed using DerSimonian and Laird random-effects models. We further investigated SLE risk associated with wine, beer, and liquor intake.Results: We identified 125 incident SLE cases in NHS and 119 in NHSII. Mean ± SD age at SLE diagnosis was 55.8 ± 9.5 years in NHS and 43.4 ± 7.7 years in NHSII. Compared to no alcohol intake, the meta-analyzed multivariable HR for cumulative alcohol consumption ≥5 gm/day was 0.61 (95% confidence interval [95% CI] 0.41-0.89). When limiting alcohol exposure to >4 years prior to SLE diagnosis, the multivariable HR was similar: 0.61 (95% CI 0.41-0.91). Women who drank ≥2 servings/week of wine had significantly decreased SLE risk (HR 0.65, 95% CI 0.45-0.96) compared to women who did not drink wine.Conclusion: In these large prospective cohorts, we demonstrated an inverse association between moderate alcohol consumption (≥5 grams or 0.5 drink/day) and SLE risk in women. [ABSTRACT FROM AUTHOR]