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Earlier studies have concluded that the religious sphere is less open to creativity than are other areas of human activities. Also, it has been suggested that artistic freedom and creative expression are unwelcome in the domain of religious iconography. In the present study, we address this subject with regard to children's artistic expression of the divine (n = 1703) in five different cultural and religious environments: Japanese (Buddhism and Shinto), Iranian (Islam), Russian-Buryat (Buddhism, shamanism), Russian Slavic (Christian Orthodoxy) and French-speaking Swiss (Catholic and reformed Christianity). The Consensual Assessment Technique was used to access the creativity. The results globally supported the previous research on the positive role that domain knowledge plays in creativity. It is likely that the exposure to knowledge in the religious domain through education would not negatively impact on children's creativity in the domain of pictorial representations of the divine, at least in secularized societies. Results also revealed that a child's creative expression could be a function of his or her age. Obviously, with age and knowledge of the religious domain, older children would go more often beyond the simplistic or conventional representations of the divine. As for gender, no effect was found in four out of five samples.

Contemplative approaches rooted in Buddhist traditions have been linked to the attenuation of response to social stress. Anticipatory cognitive appraisals of social situations potentially represent a mechanism explaining the stress-reducing effects of contemplative practices. The cognitive appraisal of threat is associated with an anticipated loss of social self-esteem. In contrast, the cognitive appraisal of challenge involves recognizing the potential for gain or growth in stressful situations and is associated with a more adaptive cardiovascular response. In this secondary analysis of a randomized controlled experiment performed in Switzerland, we evaluated the effects of two contemplative interventions on cognitive appraisals of challenge and threat and associated physiological profiles. The interventions were a standard Mindfulness-Based Stress Reduction (MBSR) program and a new program (MBSR-B), which included several elements from Buddhist practices. After an eight-week intervention, participants completed the Trier Social Stress Test (TSST) and underwent the assessment of primary cognitive appraisals and cardiovascular response to stress. The results demonstrated greater challenge appraisal in the MBSR (n = 20) and MBSR-B (n = 21) groups compared to Control (n = 24), and MBSR-B participants scored higher on the challenge than threat appraisal. At the physiological level, the groups did not differ on changes in cardiac output and total peripheral resistance. Still, an exploratory analysis demonstrated that the MBSR-B group's cardiovascular profile best resembled challenge appraisal. The results suggest that contemplative approaches foster challenge appraisal, contributing to a more adaptive response to stress. [ABSTRACT FROM AUTHOR]

Simple Summary: Incidence of brain metastases from genito-urinary cancers has increased over the last years due to improved imaging techniques and better survival outcomes for patients even at an advanced metastatic stage thanks to therapeutic advances. However, no clear consensus exists on their management, and every case ought to be discussed in a multidisciplinary panel. We perform a single-centre retrospective study to report on incidence, patient demographics, clinicopathological characteristics, and treatment modalities. We also manage to identify predictive factors of outcome. Background: Incidence of brain metastases is precisely unknown and there is no clear consensus on their management. We aimed to determine the incidence of brain metastases among patients with genito-urinary primaries, present patients' characteristics and identify prognostic factors. Method: We identified 51 patients treated in Geneva University Hospitals between January 1992 and December 2019. We retrospectively correlated their overall survival with 23 variables. We repeated a multivariate analysis with significant variables. Results: Overall incidence of Brain Metastases (BMs) among Genito-Urinary (GU) patients is estimated to be 1.76% (range per primary GU tumour type: 0.00–6.65%). BMs originate from germ cell tumours in two cases (3.92%), from urothelial cell carcinoma in 15 cases (29.41%), from prostate cancer in 13 cases (25.49%), and from renal cell carcinoma in 21 cases (41.18%); there are no BMs from penile cancer in our cohort. The median age at BM diagnosis is 67 years old (range: 25–92). Most patients (54%) have a stage IV disease at initial diagnosis and 11 patients (22%) have BM at initial diagnosis. Only six patients (12%) are asymptomatic at BM diagnosis. The median Overall Survival (OS) from BM diagnosis is 3 months (range: 0–127). Five patients (10%) are long survivors (OS > 24 months). OS is significantly influenced by patient performance status and administration of systemic treatment. In the absence of meningeal carcinomatosis, OS is influenced by systemic treatment and stereotactic radiosurgery. We also apply the Graded Prognostic Assessment (GPA) score to our cohort and note significant differences between groups. Conclusion: Brain metastases from solid tumours is not a uniform disease, with a prognosis varying a lot among patients. The optimal management for patients with genito-urinary malignancies with brain metastases remain unclear and further research is needed. [ABSTRACT FROM AUTHOR]

Chronic non-cancer pain is a highly prevalent health issue with personal and societal consequences. Patients suffering from chronic non-cancer pain are mainly cared for by primary care physicians, but research shows that the latter perceive treating chronic pain as difficult. This qualitative descriptive study aimed to explore how primary care physicians in Switzerland manage patients with chronic non-cancer pain and what factors influence patient management. Data were collected through semi-structured interviews amongst primary care physicians in the German speaking part of Switzerland. A thematic analysis of the interviews allowed to identify four main themes: Investigation of chronic pain; patient-provider relationship; patient characteristics, and medical recommendations. These themes were closely interconnected and influenced each other. Physicians not only enquired about the origin of pain but also about the patients' beliefs and expectations towards it. They stressed the role of communication in fostering a good patient-physician relationship and to help patients cope with their pain. In addition to purely medical considerations, the psychological, social and economic situation of their patients and their possible impacts on the management of chronic non-cancer pain played a crucial role when recommending a treatment. This study highlighted the complexity of chronic pain management, which entails that primary care physicians need to figure out a unique strategy for each patient. By integrating patients' values and beliefs, as well as socioeconomic aspects, primary care physicians are in a position to take the lead in chronic non-cancer pain management. However, considering the burden of this disease, more continuous medical education on chronic pain is needed for primary care physicians, especially to better take into account the social determinants of pain. [ABSTRACT FROM AUTHOR]

In this article, we present an analysis of individual factors that influence how well a person can read and understand a text in an unfamiliar, but closely related language--the basis of the so-called teaching of intercomprehension. Our work analyzes these relations from two normally separate perspectives. The first perspective focuses on how individual linguistic profiles affect skills in receptive multilingualism, while the second examines the influence of personality traits on these abilities, an aspect that has not yet been studied in relation to receptive multilingualism. It also discusses the effect of a student's educational background, a major factor for success at school. 180 lower secondary students were asked to perform a task in receptive multilingualism; this task was followed by a psychometric personality test and questions designed to ascertain the linguistic background of the students, their attitude toward language learning, and their interest in the task. The results permit us to identify individual factors that exert more (and less) influence on the processes at work in receptive multilingualism, including personality traits (in particular extroversion and openness to new experiences) and attitudes toward language learning.

Studies tell us that more than 50% of the Romanian people age 65 and older live in rural areas. At the same time, among people living in rural areas, the elderly are vulnerable to isolation and loneliness in contemporary Romania. Studies also us that, for Romanian seniors who do not live in senior care facilities, coverage for major needs (especially financial, material, and health-related needs) is often insufficient or inaccessible. However, material or health aspects alone do not determine quality of life. The religious or spiritual dimension also contributes to well-being, according to numerous studies. This is why the spiritual care of elderly people living at home is important; it contributes to their well-being. In this work, we describe a research project carried out in Switzerland, in the canton of Vaud. The elderly people living in care facilities and others benefiting from home care serve as a source of inspiration as we contemplate how to integrate the spiritual dimension when caring for elderly people living at home, especially in rural areas. [ABSTRACT FROM AUTHOR]

Approved in 1999 by the Swiss Parliament, the Swiss Virtual Campus (SVC) project debuted in 2000 with the goal of promoting an information society in Switzerland. The University of Geneva has been actively involved with building the SVC and the European virtual campus e-LERU, a two-year project in which eight European countries partnered to implement research-based education at a distance. These two cross-institutional virtual campuses brought together traditional universities having unequal experience in distance education. Focusing on the SVC experience, this report identifies critical characteristics of such multifaceted projects with the goal of improving their chances for success. The construction and funding phases of the SVC are complete, and the next phase will concern sustainability, which clearly represents a major challenge for virtual campuses. Radical changes in the higher education curriculum might be needed to improve the virtual campuses' chances for success. (Contains 3 tables, 1 figure and 33 endnotes.)

Online education encompasses a variety of technologies, one of which is lecture capture--a long-standing practice at the University of Geneva. The faculty of arts has recorded most of its lectures on audiotapes since the 1970s, well before the World Wide Web existed. Modernization of the recording technologies, however, which until recently consisted of magnetic tapes, was necessary for online courses to efficiently share lectures with off-campus students. This technological upgrade inevitably had implications for the audiovisual (A/V) operating staff of librarians and technicians who have traditionally been caretakers of the lecture-capture process. To ease the acceptance of a new, automatic lecture-recording system, a close collaboration between the operating staff and IT engineers was established during the project's conception. This article describes how the University of Geneva successfully carried out this project while respecting several constraints, akin to those faced by many other academic institutions. (Contains 14 endnotes and 5 figures.)

Objectives: The objectives were to describe patients' experiences of cancer care in Switzerland and explore the variation of these experiences by type of cancer. Methods: The Swiss Cancer Patient Experiences (SCAPE) study was a cross‐sectional, multicentre survey conducted in 2018. Adult patients (n = 7145) with breast, prostate, lung, colorectal, skin or haematological cancer from four large hospitals in French‐speaking Switzerland were invited to complete a survey. Logistic regressions were used to assess whether experiences varied according to cancer type, adjusting for confounders. Results: Of the 3121 persons who returned the survey (44% response rate), 2755 reporting an eligible cancer were included in the analyses. Participants' average score for overall care was 8.5 out of a maximum score of 10. Higher rates of positive experiences were found for nurse consultations (94%), diagnostic tests (85%) and inpatient care (82%). Lower positive responses were reported for support for people with cancer (70%), treatment decisions (66%), diagnosis (65%) and home care (55%). We observed non‐systematic differences in experiences of care by cancer type. Conclusions: This large study identified that cancer patient experiences can be improved in relation to communication, information and supportive care aspects. Improvement efforts should target these areas of care to enhance responsiveness of cancer care. [ABSTRACT FROM AUTHOR]

Purpose: About 20% of all fractures in children occur at the lower extremity. This study aims to investigate the epidemiology and injury pattern of lower extremity fractures within the pediatric population consulting a tertiary referral hospital in Switzerland. Methods: Study population included all patients up to 16 years presenting with a lower extremity fracture over a period of one year. Recorded data were age, gender, side, season of the year, mechanism, type of fracture and applied treatment. Results: Fractures of the lower extremity represent 23% of all fractures with a mean age of 9 years and 6 months. The tibia, with 94 fractures (38%), represents the most frequently injured bone. Peak incidence is seen in winter and 24% of tibia shaft fractures were due to board sports. Overall, 82% of fractures were treated by cast with or without closed reduction, and only 18% requested surgery. Conclusion: Board sports seems to be a leading cause of tibial shaft fracture in our region. Nevertheless, only 18% of fractures had recourse to an orthopedic surgeon, hence the importance of the teaching quality of pediatric residents for conservative fracture treatment. [ABSTRACT FROM AUTHOR]

Background: To curb the spread of the first wave of the COVID-19 pandemic, the Swiss government declared a state of health emergency and ordered a legal restriction concerning the opening of healthcare institutions. In this study, we aimed to assess the proportion of traditional Chinese medicine (TCM) physicians and therapists who consulted patients regarding COVID-19 during the first wave of the pandemic in 2020 in Switzerland, as well as the extent to which COVID-19 affected their practices during the same period. Methods: A retrospective study was performed by using a questionnaire from January to April 2021 among a random sample of TCM physicians and therapists based in Switzerland. The survey included questions on demographic characteristics, opening status of practices, channels of communication used for the medical encounter, and experience in managing the prevention, acute, and recovery stages of COVID-19 infection. Results: Among the 320 participants, 76% consulted a patient regarding COVID-19 at least once. Overall, physicians and therapists consulted more patients during recovery (76.3%) and prevention (67.8%) than during the acute stage (19.8%) of the disease. Acupuncture was the most frequently used technique among TCM therapists and physicians consulting for prevention (80.4%) and recovery (92.5%), whereas Chinese pharmacopeia was the most used technique among those consulting for the acute stage (59.3%). Of those who closed their practices from March to April 2020 but kept consulting, telephone (30.4%) and home visits (29.9%) were the two principal methods of consultation. Conclusions: The restriction concerning the opening of practices induced a loss of the health workforce, especially among TCM therapists. Nonetheless, TCM therapists and physicians consulted patients regarding COVID-19, especially during the recovery stage. As there is a demand for the use of TCM in the context of COVID-19, it raises the need for a better consideration of TCM in the Swiss health care system. [ABSTRACT FROM AUTHOR]

Objectives: To determine the prevalence of use of complementary medicine (CM) in Switzerland in 2017, its development since the 2012 Swiss Health Survey, and to examine specific and non-specific sociodemographic, lifestyle and health-related determinants of CM use as compared to determinants of conventional health care use. Materials and methods: We used data of 18,832 participants from the cross-sectional Swiss Health Survey conducted by the Swiss Federal Statistical Office in 2017 and compared these data with those from 2012. We defined four CM categories: (1) traditional Chinese medicine, including acupuncture; (2) homeopathy; (3) herbal medicine; (4) other CM therapies (shiatsu, reflexology, osteopathy, Ayurveda, naturopathy, kinesiology, Feldenkrais, autogenic training, neural therapy, bioresonance therapy, anthroposophic medicine). Independent determinants of CM use and of conventional health care use were assessed using multivariate weighted logistic regression models. Results: Prevalence of CM use significantly increased between 2012 and 2017 from 24.7% (95% CI: 23.9–25.4%) to 28.9% (95% CI: 28.1–29.7%), respectively, p<0.001). We identified the following independent specific determinants of CM use: gender, nationality, age, lifestyle and BMI. Female gender and nationality were the most specific determinants of CM use. Current smoking, being overweight and obesity were determinants of non-use of CM, while regular consumption of fruits and/or vegetables and regular physical activity were determinants of CM use. Conclusion: Prevalence of CM use significantly increased in Switzerland from 2012 to 2017. Gender, nationality, age, lifestyle and BMI were independent specific determinants of CM use as compared to conventional health care use. Healthier lifestyle was associated with CM use, which may have potentially significant implications for public health and preventive medicine initiatives. The nationality of CM users underlines the role of culture in driving the choice to use CM but also raises the question of whether all populations have equal access to CM within a same country. [ABSTRACT FROM AUTHOR]

Background: Pediatric integrative medicine, combining conventional and complementary medical approaches for children and adolescents, is an integral part of the health care system in Switzerland. However, there is still a lack of complementary and integrative medicine topics in training and continuing educational programs. For the first time on a national level, the 2021 annual conference of the Swiss Society of Pediatrics was entirely dedicated to the topic of integrative medicine. Methods: Using a cross-sectional online survey, this study investigated congress participants' evaluation and feedback with the aim to assess whether the program had met their objectives and to get empirical data on their attitude, expectations and needs regarding pediatric complementary and integrative medicine. Descriptive methods were used to present the results. Results: Among 632 participants of the conference, 228 completed the evaluation form (response rate 36%). The overall feedback about the congress and the main theme of pediatric integrative medicine was clearly positive. The majority of respondents had achieved their educational objectives including complementary and integrative medicine issues. 82% were motivated to learn more about complementary and integrative medicine and 66% were stimulated to integrate complementary therapies into their professional practice. Conclusion: This study from Switzerland confirms the interest in integrative medicine among pediatricians and supports the need for pre- and postgraduate pediatric training on topics related to complementary and integrative medicine. Developing and adapting training and continuing medical education based on evaluations of participant feedback can promote professional development and improve patient care for the benefit of physicians and patients. [ABSTRACT FROM AUTHOR]

Background The increasing incidence of candidemia and emergence of drug-resistant Candida species are major concerns worldwide. Long-term surveillance studies are needed. Methods The Fungal Infection Network of Switzerland (FUNGINOS) conducted a 15-year (2004–2018), nationwide, epidemiological study of candidemia. Hospital-based incidence of candidemia, Candida species distribution, antifungal susceptibility, and consumption were stratified in 3 periods (2004–2008, 2009–2013, 2014–2018). Population-based incidence over the period 2009–2018 derived from the Swiss Antibiotic Resistance Surveillance System (ANRESIS). Results A total of 2273 Candida blood isolates were studied. Population and hospital-based annual incidence of candidemia increased from 2.96 to 4.20/100 000 inhabitants (P =.022) and 0.86 to 0.99/10 000 patient-days (P =.124), respectively. The proportion of Candida albicans decreased significantly from 60% to 53% (P =.0023), whereas Candida glabrata increased from 18% to 27% (P <.0001). Other non- albicans Candida species remained stable. Candida glabrata bloodstream infections occurred predominantly in the age group 18–40 and above 65 years. A higher proportional increase of C glabrata was recorded in wards (18% to 29%, P <.0001) versus intensive care units (19% to 24%, P =.22). According to Clinical and Laboratory Standards Institute, nonsusceptibility to fluconazole in C albicans was observed in 1% of isolates, and anidulafungin and micafungin nonsusceptibility was observed in 2% of C albicans and C glabrata. Fluconazole consumption, the most frequently used antifungal, remained stable, whereas use of mold-active triazoles and echinocandins increased significantly in the last decade (P <.0001). Conclusions Over the 15-year period, the incidence of candidemia increased. A species shift toward C glabrata was recently observed, concurring with increased consumption of mold-active triazoles. [ABSTRACT FROM AUTHOR]

Karst aquifers may convey significant sediment fluxes, as displayed by the intense turbidity peaks commonly observed at karst springs. The understanding of the origin of the suspended solids discharged at springs is key in assessing spring vulnerability and securing drinking water quality. The mechanisms for turbidity generation and sediment transport in karst are however difficult to investigate because of the general lack of access to the karst conduits. These processes have been examined in the Milandre Cave, which hosts a karst drain of regional importance, for more than 10 years by means of turbidity monitoring both inside and at the outlets of this karst system. Additionally, the composition of the suspended load (particle‐size distribution and Escherichia coli content) has been monitored over the course of a flood event. These data are compared against a numerical simulation of the mean boundary shear stress inside the conduit network. The following conceptual model for sediment transport through the system is derived: during minor flood events, most of the turbidity comes from underground sediment remobilization, while during medium to intense flood events, soil‐derived turbidity also reaches the spring. Hydraulics in the epiphreatic zone is tightly linked with autochthonous turbidity generation (mostly during the flooding and the flushing of conduits). In comparison, allochthonous turbidity is associated with finer particles, higher E. coli, and higher UV fluorescence. This improves the overall understanding of turbidity generation and could help the monitoring and forecast of pollution events at drinking water supplies. Key Points: Based on long‐term monitoring and numerical modeling a conceptual model for turbidity generation in the Milandre karst aquifer is proposedTurbidity peaks originating from soil erosion (allochthonous) and from karst sediment remobilization (autochthonous) have been distinguishedThe flooding and the emptying of epiphreatic conduits are pointed out as main mechanisms for autochthonous turbidity generation [ABSTRACT FROM AUTHOR]

Background: The prevalence of complementary and alternative medicine (CAM) use and the modalities used by pediatric oncology patients vary widely across studies. In addition, the changes in the use of CAM over the course of treatment are understudied. Thus, this study aimed to explore (1) CAM use by pediatric oncology patients in relation to specific time intervals and (2) communication about CAM use between parents and oncologists. Methods: This retrospective cross-sectional study was conducted among parents of children diagnosed with cancer at a Swiss pediatric hematology-oncology center by means of an online questionnaire. Questions were related to their child's CAM use over different time intervals, sources of information about CAM use, and communication with the oncologists. Results: Among 140 respondents, CAM was used by 54.3% of patients before diagnosis and 69.3% of patients after diagnosis. During each defined time interval, between 50 and 58.8% of the patients used at least one CAM. Homeopathy was the most popular CAM modality used during oncology treatment, during the first year after treatment, and between 1 and 5 years after the end of treatment. Osteopathy was the most popular CAM ≥5 years after the end of oncology treatment. Forty percent of respondents did not discuss CAM with their oncologist. Conclusions: The high prevalence of CAM use and the different trends of use during the oncology care pathway and afterward underline the need to increase communication about CAM in the pediatric oncology setting, notably regarding benefits and risks of interaction with oncology treatment. [ABSTRACT FROM AUTHOR]

Background: Osteopathy is commonly used for spinal pain, but knowledge about back pain management by osteopaths is scarce. Objective: The aim of this study was to survey osteopaths across the French-speaking part of Switzerland about the scope of their practice and their management of patients with back pain. Design: This cross-sectional observational study was based on an online survey conducted from March to June 2017. Setting and participants: All registered osteopaths of the French-speaking part of Switzerland were asked to complete the survey. Outcome measures: In addition to descriptive statistics (practice characteristics, patients' profiles, scope of treatment modalities, health promotion, research, and osteopathic practice), we explored variables associated with osteopaths' practice, such as age and gender. Results: A total of 241 osteopaths completed the questionnaire (response rate: 28.8%). Almost two thirds of osteopaths were female. Ages ranged from 25 to 72 years with an overall mean of 42.0 (SD 10.7) years. Male osteopaths reported more weekly working hours than female osteopaths did (38.2 [SD 11.0] vs 31.6 [SD 8.9], respectively, p<0.001). Almost a third (27.8%,) of osteopaths could arrange an appointment for acute conditions on the same day and 62.0% within a week. Acute or subacute spinal conditions, mainly low back and neck pain, were the most frequent conditions seen by our respondents. For 94.4% of osteopaths, one to three consultations were required for the management of such conditions. Conclusion: Osteopaths play a role in the management of spinal conditions, especially for acute problems. These findings, combined with short waiting times for consultations for acute conditions, as well as prompt management capabilities for acute low back and acute neck pain, support the view that the osteopathic profession constitutes an added value to primary care. [ABSTRACT FROM AUTHOR]

Scarce data exist on the use of complementary and alternative medicine (CAM) by asylum seekers in Switzerland and their perception of discrimination. A cross-sectional study assessed the prevalence and type of CAM used by asylum seekers in one region of Switzerland and evaluated their self-perceived discrimination. Among the 61 asylum seekers who participated, lifetime prevalence of CAM use was 46%, with 28% reporting its use during the last year. Herbal medicine was the most frequently used CAM. Self-perceived discrimination was reported by 36% of asylum seekers, mainly related to their national origins. CAM users had a tendency to report more discrimination than non-users (44% vs. 30%). CAM use is prevalent among asylum seekers. Considering the importance of herbal medicine use and that only half of the respondents disclosed CAM use to their physician, clinicians should ask about it, notably because of potential risks of herb–drug interaction. [ABSTRACT FROM AUTHOR]

This article discusses the transformation of global brands between the 1880s and the early twenty-first century, through the example of the Swiss watch company Longines. It shows that the concept of 'global brand' changed over time and was related to the nature of the product. Until the 1970s, luxury was linked to precision. Manufacturers focused on the production of movements and adapted the design of end products to each market. Yet the paradigm shift brought about by electronics led to a new definition of luxury during the 1990s, a change which led to a new generation of global brands. [ABSTRACT FROM AUTHOR]

To speak of the Romanian village today is to consider a reality of life populated more and more by elderly people and children whose parents work outside the home, in town, or even abroad. The quality of life of the elderly remaining in the village is, in this context, a major concern for the political authorities and religious leaders. Indeed, many studies have shown that taking into account the religious and spiritual dimension contributes to the well-being of seniors. Recent research in Switzerland has highlighted the fact that many elderly people who live in senior care facilities are interested in talking about death with someone they trust. This trusted person is not necessarily the priest or chaplain. For many residents, this role is given to someone within the elderly person's network of family and friends (spouse, daughter, niece, close friend, etc.). What happens when this network is empty and the elderly person is more isolated? We propose to think about how these observations can be transposed into a practice of spiritual care adapted to the context of the Romanian village. [ABSTRACT FROM AUTHOR]

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More than 27,000 complementary medicine (CM) therapists are registered in Switzerland, but limited data are available on their occupational profile and role in the healthcare system. Herein we aimed to gain a better understanding of the professional profile of non-physician licensed therapists, focusing on acupuncture, osteopathy, and European naturopathy. This cross-sectional study was based on an online anonymous survey conducted from March to June 2017. All 1549 non-physician registered osteopaths, acupuncturists, and naturopaths in the French-speaking part of Switzerland were asked to complete the survey. We measured the therapists' demographics, training and practice characteristics, and workload. A total of 426 therapists returned the questionnaire (response rate: 27.5%). The mean age of the respondents was 46.0 years (SD 11.6) and most were women (67.8%). CM represented the main professional activity for a majority of therapists (82.8%), most of whom were independent (86.3%). The length and number of consultations per month varied across professions. Multivariate analysis showed that acupuncturists and naturopaths performed significantly fewer consults per month than osteopaths did. However, consultation length was significantly longer for acupuncturists and naturopaths than for osteopaths. Acupuncturists (71.6%) and naturopaths (64.4%) were significantly more favorable than osteopaths (27.7%) to have consultation costs covered by basic health insurance. Professional profiles differed between osteopaths, on the one hand, and naturopaths and acupuncturists, on the other, mainly regarding workload, treatment duration, and main reasons to consult. This first study to investigate a variety of therapist profiles in Switzerland provides useful information about their activities and role within the Swiss healthcare system. Although all three professions are encompassed under the same umbrella term (CM), our study showed that they have specific work cultures and areas of intervention in the healthcare system. [ABSTRACT FROM AUTHOR]

This article discusses the impact of country-of-origin labels on the global competitiveness of European industries during the second half of the twentieth century. It considers 'made-in' labels as institutional innovations and demonstrates their role in maintaining manufacturing activities in high-wage economies. To facilitate a more detailed inquiry into the topic, the paper uses a case study of the Swiss watch industry. Swiss watch companies began facing growing competition from American and Japanese firms, which had implemented mass-production methods and started relocating low value-added activities to East Asia, in the 1950s. In Switzerland, the issue was to keep the reputation of Swiss watches intact, foregrounding the high precision of the devices, and cutting production costs at the same time. Consequently, in 1971 the federal government adopted an ordinance that allowed watch companies to use the 'Swiss' name on their products as long as they kept certain activities in Switzerland. Due to the advent of electronic watches, however, the new provision could not safeguard the Swiss watch industry from a severe crisis between 1975 and 1985. Policymakers updated the 'Swiss Made' law and it was renewed in the early 1990s within a shifting context, one in which the Swiss watch industry repositioned itself toward luxury. The law became a powerful tool for regulating the luxury-watch industry. Through the example of the Swiss watch industry, the article emphasizes that understanding the impact of country-of-origin labels requires an examination of the broader context of innovation in specific industries. [ABSTRACT FROM AUTHOR]

Purpose: To investigate among primary care patients and their physicians in western Switzerland the prevalence of use, perceived usefulness, and communication about common treatments for chronic or recurrent low back pain (crLBP) including complementary medicine (CM). Patients and methods: A cross-sectional cluster observational study involving 499 crLBP patients visiting 45 primary care physicians (PCPs) was conducted from November 1, 2015, to May 31, 2016. Patients and primary care physicians completed questionnaires about lifetime use and usefulness of 30 crLBP therapies. We conducted multivariate analyses of factors associated with therapy use, including sociodemographic variables, pain duration, insurance coverage, and primary care physicians' characteristics. Results: The five most frequent modalities used at least once by patients were physiotherapy (81.8%), osteopathic treatment (63.4%), exercise therapy (53.4%), opioids (52.5%), and therapeutic massage (50.8%). For their PCPs, the five most useful therapies were physiotherapy, osteopathic treatment, yoga, meditation, and manual therapy. In multivariate analysis, the use of physiotherapy was significantly associated with longer pain duration; osteopathic treatment was associated with age under 75 years, female gender, higher education, and CM insurance coverage. Exercise therapy was associated with non-smoking and longer pain duration. Smokers were more likely and patients of PCPs with CM training were less likely to have used opioids. During their lifetime, 86.6% of the participants had used at least one CM therapy to manage their crLBP, with a mean of 3.3 (SD=2.9) therapies used per participant; 46.1% of participants reported that their PCP did not enquire about CM use. Among CM users, 64.7% informed their PCP about it. Conclusion: Patients with crLBP use a variety of treatments, including self-prescribed and unreimbursed therapies, most frequently physiotherapy and osteopathy. The results suggest that PCPs should systematically discuss with their patients the treatments they tried to manage crLBP, including CM. [ABSTRACT FROM AUTHOR]

Objectives: Complementary medicine (CM) has become increasingly available in hospital settings in several countries. Nonetheless, there are disparities in the provision and organization of CM between hospitals and even within a single hospital. This was the case at Lausanne University Hospital, where neither a registry of CM practices nor homogeneous guidelines for the provision of CM existed. The board of directors mandated the use of an internal consultant to assess practices, delineate the ward's needs, and draft proposals to structure the provision of CM services. Design: Lescarbeau et al.'s integrated model of consultation was used. Settings/Location: Academic medical center, Switzerland. Subjects: Heads of departments, medical and nurse directors, and CM practitioners. Interventions: Semi-structured interviews, online survey, and focus groups were used to focus on CM availability, needs, and practices; CM practitioner background, training, and position in the hospital; and the type of patients treated. Results: The assessment identified 15 types of CM in 51 wards, provided by CM practitioners who represented the profiles of 8 types of health care professionals. Three barriers to implementing CM were identified: heterogeneity in CM practitioners' training and project implementation, lack of CM information for patients and health care professionals, and variable access to CM among hospital wards and resulting lack in continuity of care. Three main needs regarding CM were delineated: to ensure CM quality, to provide structured interdepartmental CM clinical services, and to provide CM information to patients and health care professionals. Three action priorities were selected by the board of directors: to develop structured CM clinical services; to select CM provision based on the specific criteria of scientific evidence, therapies already available at hospital, and specific ward's needs; and to provide CM information to patients and health care professionals. Conclusions: This assessment permitted to structure CM provision according to internal consultation. [ABSTRACT FROM AUTHOR]

In this article, the authors report on an ongoing data life cycle management national project realized in Switzerland, with a major focus on long-term preservation. Based on an extensive document analysis as well as semi-structured interviews, the project aims at providing national services to respond to the most relevant researchers’ data life cycle management needs, which include: guidelines for establishing a data management plan, active data management solutions, long-term preservation storage options, training, and a single point of access and contact to get support. In addition to presenting the different working axes of the project, the authors describe a strategic management and lean startup template for developing new business models, which is key for building viable services. [ABSTRACT FROM AUTHOR]

Background: Caffeine intake is generally estimated by self-reported consumption, but it remains unclear how well self-report associates with metabolite urinary excretion. We investigated the associations of self-reported consumption of caffeinated drinks with urinary excretion of caffeine and its major metabolites in an adult population. Methods: We used data from the population-based Swiss Kidney Project on Genes in Hypertension (SKIPOGH) study. Consumption of caffeinated coffee, decaffeinated coffee and other caffeinated beverages was assessed by self- administered questionnaire. Quantification of caffeine, paraxanthine, theobromine and theophylline was performed by ultra-high performance liquid chromatography tandem mass spectrometry in 24-h urine. Association of reported consumption of caffeinated drinks with urinary caffeine derived metabolites was determined by quantile regression. We then explored the association between urinary metabolite excretion and dichotomized weekly consumption frequency of caffeinated coffee, with Receiver Operator Characteristic (ROC) analysis. Results: In the present analysis, we included 598 individuals (52% women, mean age =46 ± 17 years). Self-reported caffeinated coffee intake was positively associated with 24-h urinary excretions of paraxanthine, theophylline and caffeine (p < 0.001), whereas reported intakes of decaffeinated coffee and other caffeinated beverages showed no association. In ROC analysis, optimal discrimination between individuals consuming less than one caffeinated coffee/ week, vs. at least one coffee, was obtained for 24-h urinary paraxanthine (Area Under Curve (AUC) = 0.868, 95% Confidence Interval (CI) [0.830;0.906]), with slightly lower performance for theophylline and caffeine, whereas theobromine did not allow any discrimination. Conclusion: Our results suggest that reported consumption of caffeinated coffee is positively associated with 24-h urinary excretion of caffeine, paraxanthine, and theophylline, and may be used as a marker of caffeine intake for epidemiological studies. [ABSTRACT FROM AUTHOR]

A pragmatic and simple approach for estimating the groundwater recharge of karst aquifers in mountainous regions by extrapolation of the hydrological regimes of gauged and well-documented systems is presented. Specific discharge rates are derived using annual precipitation and spring measurements by taking into account catchment size and elevation, which are assumed to be the dominant factors. Reference sites with high data reliability are used for calibration and regional extrapolation. This is performed with normalized values employing spatial precipitation deviations and correlation with the elevation of the catchment areas. A tiered step procedure provides minimum and maximum normalized gradients for the relationship between recharge quantity and elevation for karst regions. The normalized recharge can therefore be obtained and extrapolated for any location using the spatial precipitation variability to provide an estimate of annual groundwater recharge. The approach was applied to Switzerland (approximately 7500 km2 of karst terrain situated between 200 and over 4000 m a.s.l.) using annual precipitation data from meteorological stations for the years 2000 to 2011. Results show that the average recharge rates of different Swiss karst domains range from 20 to 46 L/km2s, which corresponds to an infiltration ratio between 0.6 and 0.9 of total precipitation. Despite uncertainties inherent in the approach, these results provide a benchmark for renewable karst groundwater resources in Switzerland of about 8.4 km3/year. The approach can be applied to any other mountainous karst region, that is, where a clear relationship between elevation, precipitation and recharge can be assumed. Copyright © 2015 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

Objectives: Human studies on the role of mannose-binding lectin (MBL) in patients with invasive candidiasis have yielded conflicting results. We investigated the influence of MBL and other lectin pathway proteins on Candida colonization and intra-abdominal candidiasis (IAC) in a cohort of high-risk patients.Methods: Prospective observational cohort study of 89 high-risk intensive-care unit (ICU) patients. Levels of lectin pathway proteins at study entry and six MBL2 single-nucleotide polymorphisms were analyzed by sandwich-type immunoassays and genotyping, respectively, and correlated with development of heavy Candida colonization (corrected colonization index (CCI) ≥0.4) and occurrence of IAC during a 4-week period.Results: Within 4 weeks after inclusion a CCI ≥0.4 and IAC was observed in 47% and 38% of patients respectively. Neither serum levels of MBL, ficolin-1, -2, -3, MASP-2 or collectin liver 1 nor MBL2 genotypes were associated with a CCI ≥0.4. Similarly, none of the analyzed proteins was found to be associated with IAC with the exception of lower MBL levels (HR 0.74, p = 0.02) at study entry. However, there was no association of MBL deficiency (<0.5 μg/ml), MBL2 haplo- or genotypes with IAC.Conclusion: Lectin pathway protein levels and MBL2 genotype investigated in this study were not associated with heavy Candida colonization or IAC in a cohort of high-risk ICU patients. [ABSTRACT FROM AUTHOR]

Drilling a tunnel in a karst region requires the assessment of disturbances in the hydrogeological functioning of aquifers and flow-systems as well as disturbances for the tunnel itself. A complete characterization of the karst hydrogeological functioning and the establishment of prevention measures are essential in order to insure a suitable construction. The paper relates investigations which were conducted in the frame of the construction of a safety gallery (Sisto) in the bernese Jura (Switzerland). This gallery is located close to the outlet of a regional karst system and parallel to an existing highway tunnel, which met numerous disorders in the past due to the intersection of active karst conduits with a discharge reate exceeding 1 m/s. The KarstALEA method was applied along the Sisto trace in order to identify sections with a high probability of karst occurrences and to characterize the type of karst related problems. The main issue turned out to be related to water head and discharge, which could potentially be cut by the tunnel construction. The system discharge rate may frequently exceed 10 m/s, and most of this water could potentially flow into the tunnel. Therefore, a hydraulic model was set up in order to assess expected flow rates and heads if conduits are intersected during the construction. Based on this model and on meteorological and hydrological real-time measurements, a predictive model was established in order to anticipate high-flows events. [ABSTRACT FROM AUTHOR]

Many studies on spirituality in psychosis have shown that, compared to a nonclinical population, patients make more use of spiritual beliefs/religious practices to deal with their problems. Our research question was to test whether attachment to spiritual figures could be a good explanation for religious coping strategies in patients with psychosis. First, adult attachment was investigated in 28 patients with chronic psychosis and 18 controls, using the Adult Attachment Interview. Diagnostic evaluations were performed with the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders (4th edition, Text Revision) Axis I disorders and symptomatic evaluation with the Brief Psychiatric Rating Scale. Results also show a high prevalence of insecure avoidant attachment in patients, and suggest that a significant part of religious coping might be explained by the theory of attachment (64% of the patients, 78% of controls). The implications of these results are interpreted in light of correspondence and compensation hypotheses. [ABSTRACT FROM AUTHOR]

Objective: We investigated factors associated with masked and white-coat hypertension in a Swiss population-based sample. Methods: The Swiss Kidney Project on Genes in Hypertension is a family-based cross-sectional study. Office and 24-hour ambulatory blood pressure were measured using validated devices. Masked hypertension was defined as office blood pressure<140/90 mmHg and daytime ambulatory blood pressure≥135/85 mmHg. White-coat hypertension was defined as office blood pressure≥140/90 mmHg and daytime ambulatory blood pressure<135/85 mmHg. Mixed-effect logistic regression was used to examine the relationship of masked and white-coat hypertension with associated factors, while taking familial correlations into account. High-normal office blood pressure was defined as systolic/diastolic blood pressure within the 130–139/85–89 mmHg range. Results: Among the 652 participants included in this analysis, 51% were female. Mean age (±SD) was 48 (±18) years. The proportion of participants with masked and white coat hypertension was respectively 15.8% and 2.6%. Masked hypertension was associated with age (odds ratio (OR) = 1.02, p = 0.012), high-normal office blood pressure (OR = 6.68, p<0.001), and obesity (OR = 3.63, p = 0.001). White-coat hypertension was significantly associated with age (OR = 1.07, p<0.001) but not with education, family history of hypertension, or physical activity. Conclusions: Our findings suggest that physicians should consider ambulatory blood pressure monitoring for older individuals with high-normal office blood pressure and/or who are obese. [ABSTRACT FROM AUTHOR]

Objectives: In this population-based study, reference values were generated for renal length, and the heritability and factors associated with kidney length were assessed. Methods: Anthropometric parameters and renal ultrasound measurements were assessed in randomly selected nuclear families of European ancestry (Switzerland). The adjusted narrow sense heritability of kidney size parameters was estimated by maximum likelihood assuming multivariate normality after power transformation. Gender-specific reference centiles were generated for renal length according to body height in the subset of non-diabetic non-obese participants with normal renal function. Results: We included 374 men and 419 women (mean ± SD, age 47 ± 18 and 48 ± 17 years, BMI 26.2 ± 4 and 24.5 ± 5 kg/m, respectively) from 205 families. Renal length was 11.4 ± 0.8 cm in men and 10.7 ± 0.8 cm in women; there was no difference between right and left renal length. Body height, weight and estimated glomerular filtration rate (eGFR) were positively associated with renal length, kidney function negatively, age quadratically, whereas gender and hypertension were not. The adjusted heritability estimates of renal length and volume were 47.3 ± 8.5 % and 45.5 ± 8.8 %, respectively ( P < 0.001). Conclusion: The significant heritability of renal length and volume highlights the familial aggregation of this trait, independently of age and body size. Population-based references for renal length provide a useful guide for clinicians. Key Points: • Renal length and volume are heritable traits, independent of age and size. • Based on a European population, gender-specific reference values/percentiles are provided for renal length. • Renal length correlates positively with body length and weight. • There was no difference between right and left renal lengths in this study. • This negates general teaching that the left kidney is larger and longer. [ABSTRACT FROM AUTHOR]

Background Chronic kidney disease (CKD) represents an increasing health burden. We present the population-based prevalence of CKD and compare the CKD Epidemiology collaboration (CKD-EPI) and modification of diet in renal disease (MDRD) equations to estimate the glomerular filtration rate, using the revised CKD classification with three albuminuria classes. We also explore factors associated with CKD. Methods The Swiss population-based, cross-sectional CoLaus study conducted in Lausanne (2003–2006) included 2810 men and 3111 women aged 35–75. CKD prevalence was assessed using CKD-EPI and MDRD equations and albuminuria estimated by the albumin-to-creatinine ratio in spot morning urine. Multivariate logistic regression was used to analyse determinants of CKD. Results Prevalence [95% confidence interval (CI)] of all stages CKD was 10.0% (9.2–10.8%) with CKD-EPI and 13.8% (12.9–14.6%) with MDRD. Using the revised CKD classification, the prevalence of low-, medium-, high- and very high-risk groups was 90.0, 8.46, 1.18 and 0.35% with CKD-EPI, respectively. With MDRD, the corresponding values were 86.24, 11.86, 1.55 and 0.35%. Using the revised classification, CKD-EPI systematically reclassified people in a lower risk category than MDRD. Age and obesity were more strongly associated with CKD in men [odds ratio (95% CI): 2.23(1.95; 2.56) per 10 years and 3.05(2.08;4.47), respectively] than in women [1.46 (1.29; 1.65) and 1.78 (1.30;2.44), respectively]. Hypertension, type 2 diabetes, serum homocysteine and uric acid were positively independently associated with CKD in men and women. Conclusions One in 10 adults suffers from CKD in the population of Lausanne. CKD-EPI systematically reclassifies people in a lower CKD risk category than MDRD. Serum homocysteine and uric acid levels are associated with CKD independently of classical risk factors such as age, hypertension and diabetes. [ABSTRACT FROM AUTHOR]

In 1891 Théodore Flournoy (1854-1920) became the first Professor of Psychology to be appointed at the University of Geneva, and his teaching regularly included references to religion. His successor, Georges Berguer, who taught psychology of religion, began as privat-docent in 1910 and received a full professorship in Religious Psychology and the History of Religion in 1928. French-speaking Switzerland is one of the rare places in the world where psychology of religion has been taught continuously since the very beginning of the 20th century. The aim of this article is to shed light on this tradition and especially on Georges Berguer (retired in 1944) and Edmond Rochedieu (retired in 1965) who succeeded Flournoy. This historical enterprise concludes with some reflections on the role of the psychology of religion at the intersection of psychology and the study of religions. [ABSTRACT FROM AUTHOR]

This article offers a study of the sources of competitiveness for firms in the fashion and luxury goods industry. It focuses on Swatch Group, the world's biggest watch company, using a business history approach. Whereas most researchers give priority to marketing strategies when explaining the success of European luxury and fashion companies, this papers argues that production strategies also play a key role and must be taken into consideration. The detailed analysis of the sources for Swatch Group's competitiveness since its founding in 1983 makes it possible to highlight the importance of two main complementary strategies for supporting its growth: first, supply-chain management strategy (rationalization and globalization of production) to cut production costs; and second, rebranding strategy (shift to luxury and tradition). This case study shows that cost competition still matters in industries with high value-added and maintains that the product development strategy in this industry is more about marketing than product innovation, as product rebranding is more important than technical innovation per se. [ABSTRACT FROM AUTHOR]

Objective: To assess the importance of spirituality and religious coping among outpatients with a DSM-IV diagnosis of schizophrenia or schizoaffective disorder living in three countries. Method: A total of 276 outpatients (92 from Geneva, Switzerland, 121 from Trois-Rivières, Canada, and 63 from Durham, North Carolina), aged 18-65, were administered a semi-structured interview on the role of spirituality and religiousness in their lives and to cope with their illness. Results: Religion is important for outpatients in each of the three country sites, and religious involvement is higher than in the general population. Religion was helpful (i.e., provided a positive sense of self and positive coping with the illness) among 87% of the participants and harmful (a source of despair and suffering) among 13%. Helpful religion was associated with better social, clinical and psychological status. The opposite was observed for the harmful aspects of religion. In addition, religion sometimes conflicted with psychiatric treatment. Conclusions: These results indicate that outpatients with schizophrenia or schizoaffective disorder often use spirituality and religion to cope with their illness, basically positively, yet sometimes negatively. These results underscore the importance of clinicians taking into account the spiritual and religious lives of patients with schizophrenia. [ABSTRACT FROM AUTHOR]

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This paper presents detailed insights into the nature of innovation dynamics of an SME operating in the food industry. Furthermore, the paper highlights how Action Research has changed and enhanced SME's capability to innovate. Within the exploratory action research based case study described in this article, the researchers interacted closely with one company with regards to a newly launched innovation process over a time period of more than 18 months. The analysis contributes to the fields of action research and innovation research in three respects: First, it exemplifies how systemic action research as a method can be applied on the organisational level in the private sector. Second, it demonstrates how useful action research can be for fostering the innovativeness and creativity of a company. Lastly, the analysis illustrates the extensive time horizon of an action research project. [ABSTRACT FROM AUTHOR]

To describe the characteristics of paediatric cerebral sinus venous thrombosis (CSVT) in Switzerland. Data on clinical features, neuroimaging, risk factors, and treatment were collected for all children in Switzerland younger than 16 years of age who had CSVT between January 2000 and December 2008. A follow-up examination and a cognitive assessment were performed (mean follow-up period 26mo). Differences between neonates and children (patients older than 28d) were assessed and predictors of outcome were determined. Twenty-one neonates (14 males, seven females; mean age 9d, SD 8d) and 44 children (30 males, 14 females; mean age 8y 7mo, SD 4y 5mo) were reported. The incidence of paediatric CSVT in Switzerland was 0.558 per 100 000 per year. In neonates, the deep venous system was more often involved and parenchymal injuries were more common. The strongest predictor of poor outcome was neonatal age (odds ratio 17.8, 95% confidence interval 0.847-372.353). Most children showed global cognitive abilities within the normal range, but impairments in single cognitive subdomains were frequent. Paediatric CSVT is rare. Its outcome is poor in neonates. Most children have good neurological outcomes, but some patients have individual neuropsychological impairments. [ABSTRACT FROM AUTHOR]

Aim The aim of this study was to describe neuroimaging patterns associated with arterial ischaemic stroke (AIS) in childhood and to differentiate them according to stroke aetiology. Method Clinical and neuroimaging (acute and follow-up) findings were analysed prospectively in 79 children (48 males, 31 females) aged 2 months to 15 years 8 months (median 5y 3mo) at the time of stroke by the Swiss Neuropaediatric Stroke Registry from 2000 to 2006. Results Stroke was confirmed in the acute period in 36 out of 41 children who underwent computed tomography, in 53 of 57 who underwent T2-weighted magnetic resonance imaging (MRI) and in all 48 children who underwent diffusion-weighted MRI. AIS occurred in the anterior cerebral artery (ACA) in 63 participants and in all cases was associated with lesions of the middle cerebral artery (MCA). The lesion was cortical-subcortical in 30 out of 63 children, cortical in 25 out of 63, and subcortical in 8 of 63 children. Among participants with AIS in the posterior circulation territory, the stroke was cortical-subcortical in 8 out of 16, cortical in 5 of 16, and thalamic in 3 out of 16 children. Interpretation AIS mainly involves the anterior circulation territory, with both the ACA and the MCA being affected. The classification of Ganesan is an appropriate population-based classification for our Swiss cohort, but the neuroimaging pattern alone is insufficient to determine the aetiology of stroke in a paediatric population. The results show a poor correlation between lesion pattern and aetiology. [ABSTRACT FROM AUTHOR]

The article offers information on the Swiss Private International Law Act also known as the PIL Act which directs Swiss courts for any case dismissal with lack of jurisdiction wherein an arbitral tribunal assumed jurisdiction. It mentions a pending motion in the Swiss Parliament with the adding of Subsection 2 to PIL Act Article 7. Furthermore, the amendment provides the deference in the jurisdictional decision of the Swiss courts while the arbitral tribunal has decided on its own jurisdiction.

After the United States, Switzerland was one of the main sources of FDI to Japan in the twentieth century. Swiss multinationals that have invested there have three characteristics in common. First of all, they take a long-term perspective. The main companies present at the beginning of the twentieth century (Brown Boveri, Ciba, Nestle, Sandoz, Sulzer) were still some of the largest Swiss companies in Japan at the end of the century. Second, they gradually shifted from distribution to production during the inter-war period. Third, they backed Japan's industrialisation by strengthening historically underdeveloped sectors (chemicals) and by contributing to the growth of the manufacturing industry (machines). [ABSTRACT FROM AUTHOR]

Spirituality and religion have been found to be important in the lives of many people suffering from severe mental disorders, but it has been claimed that clinicians “neglect” their patients’ religious issues. In Geneva, Switzerland and Trois-Rivières, Quebec, 221 outpatients and their 57 clinicians were selected for an assessment of religion and spirituality. A majority of the patients reported that religion was an important aspect of their lives. Many clinicians were unaware of their patients’ religious involvement, even if they reported feeling comfortable with the issue. Both areas displayed strikingly similar results, which supports their generalization. [ABSTRACT FROM AUTHOR]

Background: The rates of cigarette smoking among patients with schizophrenia are two to four times the rates observed in the community. Spirituality and religiousness have been shown to be associated with lower smoking rates in the general population. Aims: This study assessed the role of religion in cigarette smoking among patients with schizophrenia or schizo-affective disorder. Methods: Some 115 stabilized outpatients from Geneva's public psychiatric facilities were included. Interviews were conducted to investigate spiritual and religious beliefs, religious practices and religious coping. Cigarette smoking was assessed through interviews and medical records. Results: Some 58% of patients were smokers. Two-thirds of the total sample considered spirituality as very important or essential in their every day life. Religiosity was negatively associated with tobacco use: there were more current smokers without religious affiliation than non-smokers (p < 0.05). For non-smokers, the support of their faith community was significantly more important and they reported more frequent group religious practices than smokers (p < 0.05). This relation persisted after controlling for demographic confounders (gender, age, ethnicity, education, civil status). Conclusion: In patients with schizophrenia, religion and spirituality seem to be related to smoking behaviour. Similar results were previously found in the general population. These results underscore the need for a systematic exploration of religious issues in the care of smokers with schizophrenia. [ABSTRACT FROM AUTHOR]

Presents information on a study which evaluated the range of long term vascular manifestations of Coxiella burnetii infection in Switzerland. Participants and methods; Results and discussion; Conclusions.

Background. End stage renal disease increases the risk of reactivating latent tuberculosis (LTBI). Interferon-γ release assays (IGRA) are an alternative to the tuberculin skin test (TST) for detecting LTBI. Methods. Sixty-two hemodialysis patients (46 male, 16 female, aged 65 ± 15 years) from 3 hemodialysis facilities in the Geneva area were submitted to a TST, 2 IGRA (T-SPOT.TB and QuantiFERON Gold in tube: QFT), a chest radiography, and a questionnaire to record social status, country of birth, history of prior TST, tuberculosis (TB), BCG (Bacillus of Calmette-Guérin vaccine), and any cause of immuno-suppression. LTBI was defined as prior “at risk” contact with a case of contagious TB and/or a chest X-ray suggestive of prior TB infection. Results. Positivity rate was 19% for TST, 21% for QFT and 29% for T-SPOT-TB; 8% of QFT and 11% of T-SPOT-TB were indeterminate. Agreement between IGRA was fair (κ = 0.60). After adjusting for age and BCG, OR (Odds Ratio) of having a positive QFT was 4.6-fold (p = 0.029) higher in patients with LTBI vs. those without LTBI. In contrast, no association was found between LTBI and having a positive T-SPOT.TB or a positive TST. As expected, there was a strong association between prior BCG vaccination and having a positive TST (OR 5.3, p = 0.017). QFT was the only test with a significant OR of having LTBI (adjusted OR: 4.4; 95%CI: 1.1 − 17.6; p = 0.034). Among 5 patients with definite prior TB, TST and T-SPOT.TB were positive in 1 and QFT, in 2. Conclusions. In this population, QFT was superior to TST for detecting LTBI, but both IGRAs and TST have important limitations, and are unreliable for screening for LTBI. [ABSTRACT FROM AUTHOR]