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The purpose of the present study is to delve into the process of personal management of digital information among Spanish university students in their final year and to analyze whether there are similarities or differences regarding students' gender. A non-experimental methodological design has been implemented of an exploratory type and based on a questionnaire as a single data collection instrument. The instrument was validated by means of experts' judgement, cognitive interview, and construct validity. A total of 2,054 students' surveys were collected, sourced from all areas of knowledge, in 75 public and private universities. These surveys made it possible to obtain information about the information search, selection, organization, processing, and creation processes. The results revealed that university students have a positive self-concept about their own competence for personal management of information. However, they fail to take advantage of all the possibilities that the digital world offers them. Women search the Internet for more diverse resources than men. They have better judgment when it comes to selecting and processing the information they need. Male students rely more often than female ones on digital mediums when organizing and creating information and choose to publish the information in less complex and more popular formats than their female counterparts. The conclusions of the present study match those of the majority of reviewed studies, namely regarding the organization of information, contextual and social factors which influence the management of information, such as third-party support, and also in relation to the increasing implementation of digital technologies in information management processes.

This diachronic study describes an innovative university experience consisting of the development of multimedia concept maps (MCM) in relation to social educators and social workers main intervention areas and an active discussion in online forums about the results obtained. These MCMs were prepared by students who attended the Information Technologies and Communication course as part of the Degree in Social Education and dual Degree in Social Education and Work during the academic years 2010-13 at Pablo Olavide University (Seville-Spain). Following a methodological framework based on virtual, collaborative action-research, a qualitative analysis is implemented to analyze 213 MCMs created by students and their interventions in ad hoc online discussion forums with a twofold methodological approach: firstly a qualitative analysis of word frequencies in MCM through the use of Atlas-Ti software and secondly a forum discussion categorization through a reticular, category based social network analysis using UCINET and yED Graph Editor. Among the most relevant conclusions, we can highlight that a combination of MCMs and discussion forums are highly interactive and collaborative digital resources and are especially beneficial when applied to social studies. Students were able to identify and categorize key areas of social and educational intervention, including: seniors, children, teens and drug dependence, people with disabilities, adults, mental health, socio-community care, and immigrants.

The incorporation of Universal Design for Learning (UDL) into Spanish educational legislation as a framework for addressing student diversity has been met with criticism. Three main objections can be identified. Firstly, the lack of evidence supporting its neuroscientific basis. Secondly, the scarcity of empirical data to demonstrate its efficacy for improving learning. Thirdly, the difficulty in operationalizing and implementing its framework in practice. Based on a thorough review of key literature on UDL, this paper delves into and discusses these limitations considering the theoretical and practical foundations of the model. Furthermore, research directions are pointed out to advance its development, exploring its potential as a framework for identifying barriers for learning in lesson plans. [ABSTRACT FROM AUTHOR]

Copyright of Anales de Geografía de la Universidad Complutense is the property of Universidad Complutense de Madrid and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Palaeoseismological studies play a crucial role in the seismic characterization of regions with slow moving faults. This is the case of the Central Betic Cordillera, a highly populated area where the record of prehistoric earthquakes is very scarce, despite of being one of the regions with the highest seismic hazard in Spain. We present here a palaeoseismological characterization of the Galera Fault, one of the active faults accommodating deformation in the Central Betic Cordillera. We excavated and analysed several trenches along the fault trace. We quantitatively correlate the results from these trenches, resulting in a surface rupture history involving 7 or 8 events (accounting for the epistemic uncertainties) during the last ca. 24000 yr, with a recurrence interval ranging between 1520 and 1720 yr. Further analysis of this surface rupture history seems to indicate that the Galera Fault is prone to produce earthquakes clusters, as we recorded five events in ca. 400 yr (ca. 1536-1126 BC), and only two events in the next ca. 3200 yr. Using the fault geometry and palaeoseismological data, we also carried out a seismogenic characterization of the fault. This analysis yielded a maximum expected magnitude of 6.7 ± 0.3 and a recurrence interval of 1857 yr. Furthermore, we also present a geodetic rupture scenario for the maximum expected event, involving displacements of up to 0.5 m. Finally, we discuss the possible impact of the deduced palaeoearthquakes in the development of Bronze Age human settlements located in the vicinity of the fault. Other than their intrinsic value, our results will be the basis for future seismic hazard assessment carried out in the Central Betic Cordillera. [ABSTRACT FROM AUTHOR]

Background: 'Learning by doing' is a learning model based on performing actions and gaining experience. The 'nursing process' is a systematic, rational method for providing nursing care. During their university education, nursing students need to acquire the ability to promote healthy lifestyles. Objective: To determine the effectiveness of a learning strategy based on learning by doing and grounded in the use of the nursing process, on the lifestyle of nursing students. Methods: This quasi-experimental intervention (before-after), performed over 2011–2022, involved 2300 nursing students at a university nursing school in Spain. The risk factors for chronic diseases—being a smoker, being overweight, or having high blood pressure—to which each student was exposed were recorded. Those positive for at least one risk factor selected companion students as 'support nursing students' who became responsible for designing an individualised care plan to reduce the risk(s) faced. To ensure the correct use of the nursing process, teachers approved and monitored the implementation of the care plans. Whether risk-reduction objectives were met was determined three months later. Results: The students with risk factors largely improved their lifestyles (targets for reducing smoking/body weight were met) with the help of their supporting peers. Conclusions: The learning by doing method demonstrated its effectiveness, improving the lifestyle of at-risk students via the use of the nursing process. [ABSTRACT FROM AUTHOR]

Copyright of Informacion Comercial Espanola Revista de Economia is the property of S.G.E.E.I.P.C., Secretaria de Estado de Comercio, Ministerio de Industria, Comercio y Turismo and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Purpose: To examine the effects of a low-volume repeated-power-ability (RPA) training program on repeated-sprint and change-of-direction (COD) ability and functional jumping performance. Methods: Twenty-two male elite young basketball players (age 16.2 ± 1.2 y, height 190.0 ± 10.0 cm, body mass 82.9 ± 10.1 kg) were randomly assigned either to an RPA-training group (n = 11) or a control group (n = 11). RPA training consisted of leg-press exercise, twice a week for 6 wk, of 1 or 2 blocks of 5 sets x 5 repetitions with 20 s of passive recovery between sets and 3 min between blocks with the load that maximized power output. Before and after training, performance was assessed by a repeated-sprint-ability (RSA) test, a repeated-COD-ability test, a hop for distance, and a drop jump followed by tests of a double unilateral hop with the right and left legs. Results: Within-group and between-groups differences showed substantial improvements in slowest (RSAs) and mean time (RSAm) on RSA; best, slowest and mean time on repeated-COD ability; and unilateral right and left hop in the RPA group in comparison with control. While best time on RSA showed no improvement in any group, there was a large relationship (r = .68, 90% CI .43;.84) between the relative decrement in RSAm and RSAs, suggesting better sprint maintenance with RPA training. The relative improvements in best and mean repeated-COD ability were very largely correlated (r = .89, 90% CI .77;.94). Conclusions: Six weeks of low-volume (4-14 min/wk) RPA training improved several physical-fitness tests in basketball players. [ABSTRACT FROM AUTHOR]

Purpose: To examine the effects of a novel isoinertial eccentric-overload and vibration training (EVT) paradigm on change-of-direction (COD) speed and multiple performance tests applicable to soccer. Methods: Twenty-four young male players were assigned to an EVT (n = 12) or conventional combined (CONV, n = 12) group, once weekly for 11 wk. EVT consisted of 2 sets of 6-10 repetitions in 5 specific and 3 complementary exercises. CONV used comparable volume (2 sets of 6-10 reps in 3 sequences of 3 exercises) of conventional combined weight, plyometric, and linear speed exercises. Pre- and postintervention tests included 25-m sprint with 4 x 45° COD every 5th m (V-cut test), 10- and 30-m sprints, repeat-sprint ability, countermove-ment jump, and hopping (RJ5). Results: Group comparison showed very likely to likely better performance for EVT in the COD (effect size [ES] = 1.42), 30-m (ES = 0.98), 10-m (ES = 1.17), and average power (ES = 0.69) and jump height (ES = 0.69) during RJ5. There was a large (r = -.55) relationship between the increase in average hopping power and the reduced V-cut time. Conclusions: As EVT, not CONV, improved not only COD ability but also linear speed and reactive jumping, this "proof-of-principle" study suggests that this novel exercise paradigm performed once weekly could serve as a viable adjunct to improve performance tasks specific to soccer. [ABSTRACT FROM AUTHOR]

Stress at work motivated by pressures and labour control can alter the behaviour of workers. Since the 2008 economic crisis, banking in Spain has suffered a series of massive lay-offs to adjust to the new market situation. This new financial restructuring has meant greater labour pressure to achieve the required results. Faced with this adversity, employees have experienced greater stress at work. This work analyses the effect of reinforcing employees' spiritual dimension to transcend and correctly manage work pressure and stress at work. In so doing, 601 employees from 294 financial entities of five large IBEX banks participated in this pilot project. Through a participatory methodology based on a review of the literature, the study indicators have been delimited. The data obtained have been treated using the SEM-PLS method. The results propose the incorporation of a series of tools to reinforce values and transcendent employee behaviour. [ABSTRACT FROM AUTHOR]

Objectives: To determine the factors associated with lung cancer diagnosis and mortality after detecting a solitary pulmonary nodule (SPN) in routine clinical practice, in men and in women for both chest radiograph and CT. Materials and methods: A 5-year follow-up of a retrospective cohort of of 25,422 (12,594 men, 12,827 women) patients aged ≥35 years referred for chest radiograph or CT in two hospitals in Spain (2010–2011). SPN were detected in 893 (546 men, 347 women) patients. We estimated the cumulative incidence of lung cancer at 5-years, the association of patient and nodule characteristics with SPN malignancy using Poisson logistic regression, stratifying by sex and type of imaging test. We calculated lung cancer specific mortality rate by sex and SPN detection and hazard rates by cox regression. Results: 133 (14.9%) out of 893 patients with an SPN and 505 (2.06%) of the 24,529 patients without SPN were diagnosed with lung cancer. Median diameter of SPN in women who developed cancer was larger than in men. Men who had a chest radiograph were more likely to develop a lung cancer if the nodule was in the upper-lobes, which was not the case for women. In patients with an SPN, smoking increased the risk of lung cancer among men (chest radiograph: RR = 11.3, 95%CI 1.5–83.3; CT: RR = 7.5, 95%CI 2.2, 26.0) but smoking was not significantly associated with lung cancer diagnosis or mortality among women with an SPN. The relative risk of lung cancer diagnosis in women with SPN versus those without was much higher compared to men (13.7; 95%CI 9.2, 20.4 versus 6.2; 95%CI 4.9,7.9). Conclusion: The factors associated with SPN malignancy and 5-year lung cancer mortality were different among men and women, especially regarding smoking history and SPN characteristics, where we observed a relatively high rate of lung cancer diagnosis among female non-smokers. [ABSTRACT FROM AUTHOR]

Rationale: Home respiratory polygraphy may be a simpler alternative to in-laboratory polysomnography for the management of more symptomatic patients with obstructive sleep apnea, but its effectiveness has not been evaluated across a broad clinical spectrum.Objectives: To compare the long-term effectiveness (6 mo) of home respiratory polygraphy and polysomnography management protocols in patients with intermediate-to-high sleep apnea suspicion (most patients requiring a sleep study).Methods: A multicentric, noninferiority, randomized controlled trial with two open parallel arms and a cost-effectiveness analysis was performed in 12 tertiary hospitals in Spain. Sequentially screened patients with sleep apnea suspicion were randomized to respiratory polygraphy or polysomnography protocols. Moreover, both arms received standardized therapeutic decision-making, continuous positive airway pressure (CPAP) treatment or a healthy habit assessment, auto-CPAP titration (for CPAP indication), health-related quality-of-life questionnaires, 24-hour blood pressure monitoring, and polysomnography at the end of follow-up. The main outcome was the Epworth Sleepiness Scale measurement. The noninferiority criterion was -2 points on the Epworth scale.Measurements and Main Results: In total, 430 patients were randomized. The respiratory polygraphy protocol was noninferior to the polysomnography protocol based on the Epworth scale. Quality of life, blood pressure, and polysomnography were similar between protocols. Respiratory polygraphy was the most cost-effective protocol, with a lower per-patient cost of 416.7€.Conclusions: Home respiratory polygraphy management is similarly effective to polysomnography, with a substantially lower cost. Therefore, polysomnography is not necessary for most patients with suspected sleep apnea. This finding could change established clinical practice, with a clear economic benefit. Clinical trial registered with www.clinicaltrials.gov (NCT 01752556). [ABSTRACT FROM AUTHOR]

Copyright of Revista de Historia Económica / Journal of Iberian & Latin American Economic History is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

We have decomposed the peseta/dollar real exchange rate (1870–1998) into its trend and cyclical components and used the former to proxy its time-varying equilibrium. Then, we have compared changes in the equilibrium with changes in the Spanish and the USA productivity differentials to identify years that do not fit with the Harrod–Balassa–Samuelson (HBS) hypothesis. The greatest maladjustment is found in the 1940s and 1950s, decades of strong exchange rate intervention in Spain. Conversely, the link between equilibrium and differentials adjusts to the hypothesis when using the non-intervened peseta/dollar exchange rate on the Tangier black market. These contrasting results back up the idea that exchange rate intervention, so common in developing countries, might explain their scanter evidence in favour of the HBS effect. [ABSTRACT FROM PUBLISHER]

This paper investigates the channels through which Spanish regional export promotion offices (REPOs) abroad affect bilateral exports. Using transaction data per product over the period 1995-2011, we decompose the total impact of REPOs on exports value into three margins: number of products, number of firm transactions per product and average value per transaction. We find that the export-enhancing effect of REPOs takes place mainly through an increase in the first two margins. Moreover, we also find that the pro-trade effect of REPOs is larger for more differentiated products, for non-EU destinations and is increasing with the age of the offices. [ABSTRACT FROM AUTHOR]

Background Physical activity (PA) has been shown to improve the general health of patients with chronic diseases and to prevent the onset of such conditions. However, the association between multimorbidity and PA has not been investigated in detail, and recent studies of this topic yield dissenting results. The objective of this study was to examine whether PA levels were associated with multimorbidity, self-rated health and functional limitation. Methods This was a cross-sectional study based on data from the 2009 European Health Interview Survey for Spain. The sample population included 2,190 adults over 15 years of age. The independent variables were multimorbidity (measured as the number of chronic diseases), activity limitations, and self-rated health status. The dependent variable was PA level, measured as a) a continuous variable in metabolic equivalents (METs) and b) a dichotomous variable based on international recommendations (74 years), using multivariate linear and logistic regression models that were adjusted for age, educational level and employment status. Results An inverse association was found between PA and multimorbidity among older males and young females between 16-24 years. This negative association was also observed among males aged 25-44 years when analysing PA as a dichotomous variable. Self-rated health status was directly related to the achievement of minimum PA levels among middle-aged and older individuals, but the opposite happened among the youngest group of females. Significant associations between the existence of activity limitations and the performance of lower volumes of PA were consistently observed among subjects over 44 years. Conclusions There is an inverse association between multimorbidity and PA in the youngest and oldest age groups. In addition, both low self-rated health status and the presence of functional limitations were related to lower PA in most of the examined population groups. These features should be considered in the design and implementation of community-based approaches to promoting PA, if further corroborated in longitudinal studies. [ABSTRACT FROM AUTHOR]

Objective. The aim of this study was to assess the efficacy of anti-TNF-α therapy in refractory uveitis due to Behçet’s disease (BD).Methods. We performed a multicentre study of 124 patients with BD uveitis refractory to conventional treatment including high-dose corticosteroids and at least one standard immunosuppressive agent. Patients were treated for at least 12 months with infliximab (IFX) (3–5 mg/kg at 0, 2 and 6 weeks and then every 4–8 weeks) or adalimumab (ADA) (usually 40 mg every 2 weeks). The main outcome measures were degree of anterior and posterior chamber inflammation, visual acuity, macular thickness and immunosuppression load.Results. Sixty-eight men and 56 women (221 affected eyes) were studied. The mean age was 38.6 years (s.d. 10.4). HLA-B51 was positive in 66.1% of patients and uveitis was bilateral in 78.2%. IFX was the first biologic agent in 77 cases (62%) and ADA was first in 47 (38%). In most cases anti-TNF-α drugs were used in combination with conventional immunosuppressive drugs. At the onset of anti-TNF-α therapy, anterior chamber and vitreous inflammation was observed in 57% and 64.4% of patients, respectively. In both conditions the damage decreased significantly after 1 year. At baseline, 50 patients (80 eyes) had macular thickening [optical coherence tomography (OCT) >250 μm] and 35 (49 eyes) had cystoid macular oedema (OCT>300 μm) that improved from 420 μm (s.d. 119.5) at baseline to 271 μm (s.d. 45.6) at month 12 (P < 0.01). The best-corrected visual acuity and the suppression load also showed significant improvement. After 1 year of follow-up, 67.7% of patients were inactive. Biologic therapy was well tolerated in most cases.Conclusion. Anti-TNF-α therapy is effective and relatively safe in refractory BD uveitis. [ABSTRACT FROM PUBLISHER]

The article discusses a study of bench press repeated power ability testing and young basketball players, focusing on test reliability, usefulness, and determinants. According to the article, the reliability of the bench press test indicates that upper-body repeated power ability can be measured using it. Variable analysis is mentioned.

Copyright of Cuadernos de Trabajo Social is the property of Universidad Complutense de Madrid and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Purpose – The aim of this paper is to compare the particular characteristics of industrial SMEs in low- and high-income regions from the perspective of their "entrepreneurial quality". Design/methodology/approach – Based on three groups of factors, (personal characteristics of entrepreneurs, entrepreneurial orientation and productive dependence of firms), which define entrepreneurial quality (EQ), the empirical analysis is focused on testing whether industrial SMEs in three Spanish regions with low per capita income present different EQs to those of industrial SMEs in three other Spanish regions with high per capita income. Data was obtained from a survey addressed to the person in the role of entrepreneur in each of these firms. Since the dependent variable is dichotomous, the logistic regression model is applied in this study. Findings – Results show there is a relationship between the regional levels of development and the entrepreneurial quality of the industrial SMEs. In low-income regions, the level of EQ is lower due to several factors. Firstly, these entrepreneurs have lower educational background, a lack of previous experience, and are more often led by pushing motivations; secondly, these industrial SMEs have lower entrepreneurial orientation when measured through innovation and proactiveness; finally, relations between firms are characterized by a higher productive dependence. Originality/value – This study offers a significant contribution by specifying the concept of EQ and its relationship with the degree of economic development. Likewise, a policy implication derived from the results is the need to improve the human capital of entrepreneurs in low-income regions. [ABSTRACT FROM AUTHOR]

The goal of this paper is to assess the impact of the euro on the relationship between firm size and exports. We employ previous new-new trade theory models to derive some hypotheses that are tested using a representative sample of Spanish manufacturing firms. The results indicate that the introduction of the euro has remarkably weakened the role of firm size in the decision to export to the Eurozone. What is more, the change in the proportion of exports to the Eurozone is negatively related to firm size. Our results suggest that the euro has reduced the threshold size in order to export to Eurozone countries. [ABSTRACT FROM AUTHOR]

The of Franco's dictatorship (1975) and the admittance to the European Union (1986) enable Spain to get strong financial support (subsides) from the Agrarian Undertaking Funds (FEOGA) and from the Common Agricultural Policy (PAC). These investments had changed Spain into an industrialized and agricultural country. In the last decades the Alicante Province has undergone profound processes of socio-environmental and territorial changes, being water the main aspect of environmental sustainability of the productive systems (industrial and agricultural), as well as the strong investments into touristic areas. As regard to the agrarian structure, inside the Alicante province prevails the small rural properties with dry (grape, olive, etc.) and irrigated (vegetables, citrus, etc.) farming. Therefore, the implantation of agricultural policies from the European Union into the Alicante province, by the concept of rural multi-functionality, has increased the agrarian concentration, the pauperization of the small producers and has increased also the competition with external products and the incentive to the speculation, being the tourism the main vector. [ABSTRACT FROM AUTHOR]

Copyright of Cuadernos de Trabajo Social is the property of Universidad Complutense de Madrid and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The article discusses the historiography of the revolutionary and emancipatory movements in Spain and its American colonies at the beginning of the 18th century. The author discusses the change in political system from monarchy to republics, considers its social and political impact in Latin America and Spain and reflects on the historiography of the 19th century Iberoamerican world.

This article estimates the effect of Spanish regional trade agencies abroad on exports using the gravity model. The results indicate that regional agencies increase trade. The estimated impact seems to be larger than that of Spanish embassies and consulates. Moreover, a disaggregated analysis shows that this effect is not evenly distributed across Spanish regions. Este artículo estima el efecto de las delegaciones comerciales regionales en el extranjero sobre las exportaciones utilizando el modelo de gravedad. Los resultados indican que las delegaciones regionales fomentan el comercio exterior. El impacto estimado parece ser mayor que el de las embajadas y consulados españoles. Por otro lado, un análisis desagregado muestra que este efecto no se distribuye uniformemente entre las regiones españolas. [ABSTRACT FROM AUTHOR]

This paper analyses the border effect in Spain using a unique dataset on intranational trade flows over the period 1995–98. The results indicate that, after controlling for market size and distance, Spanish regions trade around 22 times more with the rest of Spain than they do with OECD countries. Moreover, the size of the Spanish bias is lower in the case of the Spanish regions’ exports than in the case of imports, although the difference is not statistically significant in most cases. Finally, the border effect is not uniform across Spanish regions. [ABSTRACT FROM AUTHOR]

This paper underlines the relevance of considering breaks in Purchasing Power Parity (PPP) tests, by studying the floating peseta over the period 1870–1935. In some cases, only the stationarity of the real exchange rate in the presence of structural breaks could be accepted. Moreover, breaks clearly improve the significance of the proportionality condition for the peseta/pound, peseta/franc and peseta/dollar exchange rates. So, since breaks are endogenously detected and seem to make economic sense, the PPP hypothesis is considered as a valid equilibrium rule for the peseta exchange rate against the currencies of Spain's main traders between 1870 and 1935. [ABSTRACT FROM AUTHOR]

Aims: To investigate the annual hospitalization rate and seasonal variation in confirmed heart failure (HF) admissions.Methods and Results: Records from all admissions to one hospital during 1 year with a HF diagnostic code were reviewed. From 1953 admissions, 595 were excluded because they did not fulfill the diagnostic criteria. A total of 1069 patients had 1358 admissions with confirmed HF. Mean age was 74.8 +/- 11.5 years, 42% were males. The admission data were matched with data from the municipal census with 537,666 people aged > or = 15 years. There were 2.5 admissions per 1000 for the adult population and 26.5/1000 in those aged > or = 80 years. There were 444 males and 625 females, giving a higher rate of admission for female patients 2.2/1000 vs. 1.7/1000 (P < 0.0001), although age adjusted rates in females were higher only for > or = 80 years. Echocardiogram was performed in 706 patients (66%), 325 (46%) had a normal ejection fraction. This proportion increased in females--64% vs. 29% males--and in older patients--55% in > or = 75 vs. 39% in < 75 years. Mortality during the first admission of 1996 was 8.3%. There was a seasonal variation in HF hospitalizations (P < 0.0001) peaking at 25% above average in January and dipping to 33% below average in August.Conclusion: The rate of HF admissions was 2.5/1000 with an elderly preponderance and a higher rate of admission in males < 80 years and in females > or = 80 years. A seasonal variation ranging from 25% above average in January to 33% below average in August was observed. [ABSTRACT FROM AUTHOR]

Describes the biodiversity of honeybee, Apis mellifera, populations from Tenerife in the Canary Islands, Spain. Assessment by restriction analysis of a mitochondrial non-coding intergenic region; Status of the intergenic region identified four mitochondrial haplotypes; Suggestion that hybridization between the endemic Apis mellifera populations and imported bees is occurring in Tenerife.

We aimed to evaluate the experience of patients with type 2 diabetes (T2DM) with healthcare received in Spain. This was a retrospective, observational study in patients with T2DM cared for in primary healthcare (PHC) centers. A cross-sectional analysis of the patients' experience data was performed using the Instrument for the Evaluation of the Experience of Chronic Patients (IEXPAC). A total of 475 patients with T2DM were recruited from 36 PHC centers, of which 248 (52.2%) completed the IEXPAC questionnaire. The IEXPAC total mean score (range 0–10) was 7 points, with an average "new relational model" score of 2.5 points. The mean continuity of care score after hospital discharge was 6.2 points. The results showed that 8% of the patients always or almost always used the internet to check their medical history, appointments or other data from their healthcare service, and 15% responded that healthcare professionals always or almost always informed them of forums or other reliable internet sites to obtain information about their illness. The study results show that there is a wide margin for improvement in the experience of patients with T2DM with healthcare in Spain, especially regarding the information patients receive or can obtain. [ABSTRACT FROM AUTHOR]

The objectives were to make a description of the hospital and the works undertaken, exposing the conditions of the agreement between the city and religious and describe changes that occur during 1894. There has been a historical documentary study during the years 2014-2015 of the files deposited in the Municipal Archives of Trujillo. The Municipal Hospital in the city of Trujillo, was destined to service citizens, sick soldiers and bystanders. The Sisters Lovers of Jesus and Mary Immaculate performed treatment of patients since the year 1890. To assist the sisters would be hired a nurse and a nurse, paid by the city. During 1894 the City Council performed changes that produced the cessation of the assistance service of religious. The changes originated by the complaints of some patients and the high costs that the City Council had to pay for hospital maintenance. With the cessation, the religious began to study a new organization of the regime and the management of the institution. [ABSTRACT FROM AUTHOR]

Second-generation anticoagulant rodenticides (SGARs) are commonly used for rodent control, affecting various non-target wildlife species. Here, blood samples from common kestrels (Falco tinnunculus, n = 70 chicks) and barn owls (Tyto alba, n = 54 chicks and 12 adults) from Southeastern Spain were analysed using HPLC-TQ. SGAR prevalence was 68.6% in kestrel chicks, 50% in barn owl chicks and 100% in adult barn owls, with multiple SGARs in both species. Prothrombin time analysis in barn owls revealed a positive correlation with blood ΣSGARs, suggesting a potential adverse effect on coagulation. Analysis of variables potentially influencing SGAR prevalence indicated that, for kestrels, it was only related to the extent of artificial surface, showing no differences across study sites. In owlets, the highest prevalence occurred in the most urbanized study site, with human population density being a key factor. This study highlights species-specific differences in SGAR exposure, likely influenced by ecological traits. Barn owls probably encounter contaminated prey near anthropized areas, with widespread SGAR use and higher presence of target rodents. Conversely, kestrels, hunting a variety of prey often near human settlements, face consistently elevated exposure from multiple sources. Understanding these variations is crucial for effective conservation and minimizing SGAR impact on non-target wildlife., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Aims: To determine the degree and factors related to non-insulin antidiabetic drug (NIAD) adherence in people with type 2 diabetes mellitus (DM2) treated in primary carecentres in Spain., Methods: We did a cross-sectional study. During the study visit, variables related todifferent clinical characteristics, Adherence to Refills and Medications Scale Spanishversion (ARMS-e) and usage of NIAD were collected. We estimated the adherence toNIADs using the proportion of days covered (PDC) equation., Results: In total, 515 participants were included in the study. The mean PDC ratio was70.6 ( ± 28.9), and 50.5% (260) were classified as good adherent (PDC ≥80). Good adherence was highest among users of metformin (67.3%) and lowest among the participants using thiazolidinedione (0.8%). The score for ARMS-e was higher in the poor adherence group. In the multivariable analysis, HbA1c and the use of GLP1-RA or SGLT-2i were negatively associated with good adherence (odds ratio [OR]: 0.67, 95% confidence interval [CI]: 0.54, 0.82, OR: 0.20, 95%CI: 0.08, 0.46; OR: 0.56, 95%CI: 0.35, 0.89, respectively)., Conclusions: Adherence to NIADs observed in our study is far from optimal. HbA1c and ARMS-e items could be used as adherence indicators to encourage treatment changes to improve T2DM control., Competing Interests: Declaration of interests The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: M.M-C has received advisory and or speaking fees from Astra-Zeneca, Bayer, Boehringer Ingelheim, GSK, Lilly, MSD, Novartis, Novo Nordisk, and Sanofi; he has received research grants to the institution from Astra- Zeneca, GSK, Lilly, MSD, Novartis, Novo Nordisk, and Sanofi. J.F-N has received advisory and or speaking fees from Astra-Zeneca, Ascensia, Boehringer Ingelheim, GSK, Lilly, MSD, Novartis, Novo Nordisk, and Sanofi; he has received research grants to the institution from Astra-Zeneca, GSK, Lilly, MSD, Novartis, Novo Nordisk, Sanofi, and Boehringer. D.A. and X.C. are full-time employees of Almirall, S.A. F.L-S has received advisory and or speaking fees from Astra-Zeneca, Boehringer Ingelheim, Lilly, MSD, Novo Nordisk, and Sanofi. B.V., S.M. and J.E. declare no conflict of interest., (Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Purpose: To find out whether elements such as public expenditure, the coverage ratio, public or private ownership, and the size of Nursing homes relate to the number of deaths in residences per COVID-19., Material and Methods: A total of 15 variables are analyzed in 17 Autonomous Communities (n = 17), where the following stand out: public expenditure per dependent person; incidence of COVID-19 in each Autonomous Community; deaths in Nursing homes by COVID-19; and analysis of places in Nursing homes. Reliability of r = 0.613. Regression analyses are carried out with the different variables, and ANOVA tests., Results: Percentages of deaths by COVID-19 in Nursing homes, between 40% and 88%, of the total of (p < 0.001, X 2 = 0.975). A relationship is established between the number of deaths from COVID-19 in Nursing homes, and the higher number of private Nursing homes (p < 0.001, X 2 = 0.633). The larger the size of the Nursing home, the more deaths by COVID-19 were recorded (p < 0.001, X 2 = 0.787), with private Nursing homes having +100 places, and public Nursing homes having +100 places (p < 0.001, X 2 = 0.808)., Conclusions: It was found that there is a relationship between the number of deaths from COVID-19 in Nursing homes, and the fact that there are a greater number of private Nursing homes in that autonomous community. It was detected that the model of Nursing home best prepared to face the COVID-19: public Nursing homes with less than 25 places., (Copyright © 2021 SEGG. Publicado por Elsevier España, S.L.U. All rights reserved.)

Aims: During the COVID-19 pandemic, concern regarding its effect on the management of non-communicable diseases has been raised. However, there are no data on the impact on cardiac implantable electronic devices (CIED) implantation rates. We aimed to determine the impact of SARS-CoV2 on the monthly incidence rates and type of pacemaker (PM) and implantable cardiac defibrillator (ICD) implantations in Catalonia before and after the declaration of the state of alarm in Spain on 14 March 2020., Methods and Results: Data on new CIED implantations for 2017-20 were prospectively collected by nine hospitals in Catalonia. A mixed model with random intercepts corrected for time was used to estimate the change in monthly CIED implantations. Compared to the pre-COVID-19 period, an absolute decrease of 56.5% was observed (54.7% in PM and 63.7% in ICD) in CIED implantation rates. Total CIED implantations for 2017-19 and January and February 2020 was 250/month (>195 PM and >55 ICD), decreasing to 207 (161 PM and 46 ICD) in March and 131 (108 PM and 23 ICD) in April 2020. In April 2020, there was a significant fall of 185.25 CIED implantations compared to 2018 [95% confidence interval (CI) 129.6-240.9; P < 0.001] and of 188 CIED compared to 2019 (95% CI 132.3-243.7; P < 0.001). No significant differences in the type of PM or ICD were observed, nor in the indication for primary or secondary prevention., Conclusions: During the first wave of the COVID-19 pandemic, a substantial decrease in CIED implantations was observed in Catalonia. Our findings call for measures to avoid long-term social impact., (Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2021. For permissions, please email: journals.permissions@oup.com.)

The aim of this paper is to study the effects of the spread of the COVID-19 virus in different regions and its impact on the economy and regional tourist flows. To this end, the researchers have been guided by a set of propositions which they have tried to demonstrate with the results obtained. This research shows that the impact of the pandemic is still being evaluated. The analysis of the relationship between the tourism sector and the pandemic outbreak in Spain provides an instructive case study to assist tourism in its recovery process. The paper delves into the impacts on the main Spanish touristic regions during the pandemic and providing implications for tourism recovery. In Spain, the tourism sector is of major economic importance, becoming one of the most vulnerable countries when crisis affects this industry. The negative image of the country due to the high infection rates has had a negative impact on travel and tourism. The Balearic Islands have been the most affected region with an 87% decrease in tourist visitors. The trips made by Spanish residents inside the Spanish territory shows the first increase found in the series analyzed. Domestic tourism not only represents an opportunity for all regions in this critical situation, but the types of accommodation also play a key role.

Objectives: To explore differences in the clinical management of men and women in the 5 years after detecting a solitary pulmonary nodule (SPN) by chest radiograph or CT in routine clinical practice., Methods: We followed up 545 men and 347 women with an SPN detected by chest radiograph or CT in a retrospective cohort of 25,422 individuals undergoing routine thoracic imaging in 2010-2011. We compared the frequency of each management strategy (no further test, immediate intervention or follow up) according to sex by means of chi-squared. We estimated the relative risk of women versus men of having been followed up instead of an immediate intervention using multivariate logistic regression. We compared by sex the time between detection of the nodule and lung cancer diagnosis, the time between diagnosis and death by means of Mann-Whitney U test and the cumulative effective dose of radiation in each management strategy by means of t test., Results: Women were more likely than men to have follow-up rather than immediate intervention (aRR = 1.8, CI 1.3-2.7, p = 0.002), particularly in those who underwent CT (aRR = 4.2, CI 1.9-9.3, p < 0.001). The median time between SPN detection and lung cancer diagnosis was higher in women (4.2 months, interquartile range (IQR) 5.1) than in men (1.5 months, IQR 16.2). The mean cumulative effective dose was 21.3 mSv, 19.4 mSv in men and 23.9mv in women (p = 0.023)., Conclusions: Our results could reflect decisions based on a greater suspicion of lung cancer in men. The incidental detection of SPNs is increasing, and it is necessary to establish clear strategies aimed to reduce variability in their management according to patient's sex., Key Points: • After incidental finding of SPN, women were less likely to receive an immediate intervention. • Accumulative radiation was higher in women than in men. • Our results could reflect decisions based on a greater suspicion of lung cancer in men.

Three hundred and fourteen red foxes ( Vulpes vulpes ) in the province of Soria, Spain, were examined for hantavirus and lymphocytic choriomeningitis virus (LCMV) infection (and were likely to have been infected by feeding on infected rodents). Immunofluorescence and western blot assays confirmed 3.5% (11/314) to have antibodies to hantaviruses, and the immune fluorescence assay showed 2.2% (7/314) to have antibodies to LCMV. The serologic status of the animals showed no statistically significant association with sex or age. Although studies on the prevalence of hantaviruses and LCMV normally focus on rodents, our results showed that foxes can provide complementary information in determined areas.

Background: Some patients with COPD may share characteristics of asthma; this is the so-called asthma-COPD overlap syndrome (ACOS). There are no universally accepted criteria for ACOS, and most treatments for asthma and COPD have not been adequately tested in this population., Materials and Methods: We performed a survey among pulmonology specialists in asthma and COPD aimed at collecting their opinions about ACOS and their attitudes in regard to some case scenarios of ACOS patients. The participants answered a structured questionnaire and attended a face-to-face meeting with the Metaplan methodology to discuss different aspects of ACOS., Results: A total of 26 pulmonologists with a mean age of 49.7 years participated in the survey (13 specialists in asthma and 13 in COPD). Among these, 84.6% recognized the existence of ACOS and stated that a mean of 12.6% of their patients might have this syndrome. In addition, 80.8% agreed that the diagnostic criteria for ACOS are not yet well defined. The most frequently mentioned characteristics of ACOS were a history of asthma (88.5%), significant smoking exposure (73.1%), and postbronchodilator forced expiratory volume in 1 second/forced vital capacity <0.7 (69.2%). The most accepted diagnostic criteria were eosinophilia in sputum (80.8%), a very positive bronchodilator test (69.2%), and a history of asthma before 40 years of age (65.4%). Up to 96.2% agreed that first-line treatment for ACOS was the combination of a long-acting β2-agonist and inhaled steroid, with a long-acting antimuscarinic agent (triple therapy) for severe ACOS., Conclusion: Most Spanish specialists in asthma and COPD agree that ACOS exists, but the diagnostic criteria are not yet well defined. A previous history of asthma, smoking, and not fully reversible airflow limitation are considered the main characteristics of ACOS, with the most accepted first-line treatment being long-acting β2-agonist/inhaled corticosteroids.

Background and Objective: We sought to study the association of glaucoma with vascular disease, with 2 independent pathways: the association of glaucoma with cardiovascular disease (CVD) and the study of ocular hemodynamic variables (OHV) in glaucoma., Material and Method: Cross-sectional study consisting of 73 patients: 25 without glaucoma, 28 primary open-angle glaucoma (POAG) and 20 normal-tension glaucoma (NTG). OHV, cardiovascular risk factors (CVRF) and CVD were determined., Results: We found a greater number of CVRF and CVD in patients affected by POAG (P=.002 and P=.016) and NTG (P=.001 and P=.010) compared to the control group. With regard to OHV, in patients suffering from POAG, we found lower systolic and diastolic velocities and higher resistance index in the central retinal artery (P<.05). Moreover, in both types of glaucoma, we found higher resistance index in the posterior ciliary artery (P<.05)., Conclusions: There is a statistically significant association between the presence of CVD and/or CVRF and glaucomatous disease, a finding that is supplemented with data from the OHV. These values indicate a worst ocular perfusion in patients with glaucomatous disease., (Copyright © 2013 Elsevier España, S.L. All rights reserved.)

Background: Asthma guidelines recommend the adoption of allergen avoidance measures (AAM). To do so, patients need to know their own allergies. However, this degree of knowledge has not yet been assessed. The aims of this study were to determine, in allergic asthma patients: i)the degree of knowledge of their own allergic sensitizations; ii)the percentage of those who knew all their allergies and, in addition, adopted AAM against all of them, and iii)the possible impact of this degree of knowledge on the level of asthma control., Patients and Methods: Descriptive, prospective and multicentre study, including 147patients from 9 Respiratory Medicine outpatient clinics. After confirming the previous allergic asthma diagnosis, a questionnaire was completed. It included asthma control and severity levels, results of previous allergy tests, and the description and number of allergic sensitizations known by the patients and AAM followed., Results: Only 72 (49%) patients knew all their allergic sensitizations and only 48 (33%) were also following AAM against all the allergens to which they were allergic. No relationship was established between the degree of knowledge of their own allergies and the level of asthma control (P=.544)., Conclusions: Overall knowledge about the allergic nature of their disease among asthmatic patients attending Spanish Respiratory Medicine Departments is inadequate. Furthermore, a higher degree of knowledge of their allergies does not seem to lead, by itself, to better asthma control. Both findings seem to question the effectiveness of current educational strategies in this field and consequently, they should be revised., (Copyright © 2012 SEPAR. Published by Elsevier Espana. All rights reserved.)

Objective: Endogenous uveitis is a major cause of visual loss mediated by the immune system. The protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene encodes a lymphoid-specific phosphatase that plays a key role in T-cell receptor (TCR) signaling. Two independent functional missense single nucleotide polymorphisms (SNPs) located within the PTPN22 gene (R263Q and R620W) have been associated with different autoimmune disorders. We aimed to analyze for the first time the influence of these PTPN22 genetic variants on endogenous non-anterior uveitis susceptibility., Methods: We performed a case-control study of 217 patients with endogenous non-anterior uveitis and 718 healthy controls from a Spanish population. The PTPN22 polymorphisms (rs33996649 and rs2476601) were genotyped using TaqMan allelic discrimination assays. The allele, genotype, carriers, and allelic combination frequencies were compared between cases and controls with χ(2) analysis or Fisher's exact test., Results: Our results showed no influence of the studied SNPs in the global susceptibility analysis (rs33996649: allelic P- value=0.92, odds ratio=0.97, 95% confidence interval=0.54-1.75; rs2476601: allelic P- value=0.86, odds ratio=1.04, 95% confidence interval=0.68-1.59). Similarly, the allelic combination analysis did not provide additional information., Conclusions: Our results suggest that the studied polymorphisms of the PTPN22 gene do not play an important role in the pathophysiology of endogenous non-anterior uveitis.

Objectives: Erythromycin resistance in Streptococcus pneumoniae is still increasing worldwide. All 78 erythromycin-resistant S. pneumoniae isolates collected from blood cultures in our hospital (2000-07) were studied and the population structure was analysed by using different mathematical diversity indexes., Methods: Erythromycin resistance determinants were screened by PCR. The population structure, including multilocus sequence typing, was analysed by using quantitative clonal diversity (diversity ratio, Simpson, Selander-Levin and Shannon mathematical indexes)., Results: The leading resistance gene was erm(B) (74.3% of the isolates), followed by the erm(B) plus mef(A) combination (17.9%) and mef(A) alone (7.7%). The most frequent serotypes were 14 (18%), 19A (15.4%) and 6B (11.5%). A polyclonal structure was detected in resistant strains, including the Spain(9V)-3, Spain(6B)-2 and Denmark(14)-32 international clones. Both genetic diversity and genetic distribution were high, particularly among clones containing erm(B) and erm(B) plus mef(A) determinants., Conclusions: The resistance determinants erm(B) and the combination of erm(B) plus mef(A) were observed within multiple S. pneumoniae bacteraemic clones. The preservation of a polyclonal structure might provide a suitable background for further evolution of antibiotic resistance.

Introduction: Childhood obesity has increased alarmingly in Europe and the USA, with a rise in the consequences of this epidemic, such as type 2 diabetes, hyperlipidemia and cardiovascular disease., Objective: To study the lipid and hormonal profile of schoolchildren in the province of Alicante and to analyze the relationship between body mass index (BMI) and the variables of interest in this study., Materials and Methods: We performed a cross-sectional epidemiological study of a cohort of schoolchildren (6-11 years) from the province of Alicante (n = 394, 204 boys and 190 girls). Height and weight were measured. We measured the following analytic variables: total cholesterol, high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), triglycerides, leptin, thyrotropin (TSH), free thyroxin (T4), insulin-like growth factor-1 (IGF-1), cortisol, androstenedione, dehydroepiandrosterone sulfate (DHEAS), testosterone and estradiol. Obesity was defined as a BMI > or = 2 SD, using the population curves in the longitudinal study of Zaragoza (Spain) as the reference., Results: When studying lipid risk, we observed that 13.5% had cholesterol levels of > 200 mg/dl, 9.4% had triglyceride levels of > 100 mg/dl and 30.5% had LDL-c/HDL-c values of > 2.2. We found a correlation between BMI and plasmatic concentrations of triglycerides (r = 0.23), IGF-1 (r = 0.211), leptin (r = 0.583), androstenedione, DHEAS, testosterone and estradiol (r = 0.35, r = 0.27, r = 0.23 and r = 0.15, respectively). There was a negative correlation between BMI and HDL-c (r = -0.21) and cortisol (r = -0.09). There was no statistically significant correlation between the degree of obesity and concentrations of cholesterol (p = 0.434) and LDL-c (p = 0.452)., Conclusions: We observed a high prevalence of lipid disturbances in children under 11 years old in our population in relation to obesity.

Different pesticides, including organophosphates (OPs), have been reported to induce oxidative stress due to generation of free radicals and alteration in antioxidant defence mechanisms. In this study, a cohort of 81 intensive agriculture workers (pesticide sprayers) was assessed twice during the course of a spraying season for changes in erythrocyte antioxidant enzymes. Acetylcholinesterase (AChE) was used as a reference biomarker. Sprayers presented lower levels of superoxide dismutase (SOD) and glutathione reductase (GR) as compared to controls independently of age, BMI, smoking habit or alcohol consumption. A positive correlation between SOD and AChE was observed at the high exposure period. Those individuals with a decrease in AChE greater than 15% exhibited lower SOD and catalase (CAT) activities at the same period. Glutathione peroxidase (GPx) and glucose-6-phosphate dehydrogenase (G6PDH) remained unaffected in the exposed population. Paraoxonase (PON1) polymorphism influenced erythrocyte CAT and GR, as subjects with the R allele presented lower CAT and higher GR levels. Whether or not the decreased enzyme activities found in this study are linked to the adverse health effects related to chronic pesticide toxicity (in which oxidative damage plays a pathophysiological role, such as cancer or neurodegenerative disorders) is an attractive hypothesis that warrants further investigation.