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A new report discusses research findings on the treatment of congenital diaphragmatic hernia (CDH) in infants. The study compared the delivery room resuscitation of infants treated with fetoscopic endoluminal tracheal occlusion (FETO) to standard care (SOC). The research found that FETO resulted in increased fetal lung volume and improved survival for infants with severe left-sided CDH. However, the delivery room resuscitation of FETO infants requires careful preparation and an experienced multidisciplinary team. The study suggests that surfactant administration should be considered in all FETO infants to clear airway secretions. [Extracted from the article]

A recent study conducted at Children's Hospital Philadelphia examined the brain development of fetuses with congenital diaphragmatic hernia (CDH) using a fetal Total Maturation Score (fTMS). The study found that neonates with CDH had a significant delay in fTMS compared to healthy controls. The researchers also discovered that placental pathology, such as fetal vascular malperfusion and chronic inflammation, may influence fetal brain development. Further investigation is needed to understand the causes and clinical impact of prenatal brain immaturity in neonates with CDH. [Extracted from the article]

A recent study conducted at Children's Hospital Philadelphia examined the factors associated with prolonged birth admission length of stay (LOS) and hospital readmission in children with congenital diaphragmatic hernia (CDH). The study found that children hospitalized for more than 76 days at birth had higher odds of readmission compared to those admitted for fewer than 35 days. Additionally, children with a non-operative feeding tube at discharge had higher odds of readmission. The research suggests that longer birth hospitalization and the presence of a non-operative feeding tube are associated with increased readmissions in the year after discharge. [Extracted from the article]

A recent research study conducted in Philadelphia has provided new insights into congenital diaphragmatic hernia (CDH), a condition where abdominal contents enter the thoracic cavity, affecting both cardiac and pulmonary development. The study found that maldevelopment of the pulmonary vasculature leads to bilateral pulmonary hypoplasia and pulmonary hypertension, contributing to the high mortality rate of CDH. The researchers emphasize the importance of understanding the different clinical phenotypes of CDH and developing individualized therapies to improve outcomes. Further research into addressing the cardiopulmonary interactions in CDH patients may lead to better morbidity and mortality outcomes. [Extracted from the article]

Keywords: Philadelphia; State:Pennsylvania; United States; North and Central America; Cardiovascular Diseases and Conditions; Diaphragmatic Hernia; Gastroenterology; Gynecology; Health and Medicine; Hernias; Hospitals; Hypertension; Lung Diseases and Conditions; Pulmonary Hypertension; Right Ventricular EN Philadelphia State:Pennsylvania United States North and Central America Cardiovascular Diseases and Conditions Diaphragmatic Hernia Gastroenterology Gynecology Health and Medicine Hernias Hospitals Hypertension Lung Diseases and Conditions Pulmonary Hypertension Right Ventricular 824 824 1 10/24/23 20231023 NES 231023 2023 OCT 23 (NewsRx) -- By a News Reporter-Staff News Editor at Respiratory Therapeutics Week -- Investigators publish new report on Lung Diseases and Conditions - Pulmonary Hypertension. Philadelphia, State:Pennsylvania, United States, North and Central America, Cardiovascular Diseases and Conditions, Diaphragmatic Hernia, Gastroenterology, Gynecology, Health and Medicine, Hernias, Hospitals, Hypertension, Lung Diseases and Conditions, Pulmonary Hypertension, Right Ventricular. [Extracted from the article]