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Few empirical studies have analyzed the return to distance higher education in different academic disciplines. This study used quantitative methods, data from a nationwide survey, and Mincerian earnings function to analyze the return to distance higher education among different disciplines in China's labor market. Results were compared with the return to face-to-face higher education and showed that the returns to face-to-face higher education were higher than those to distance higher education. Returns to the disciplines of economics and management were at a high level in both face-to-face and distance education; returns to the disciplines of literature, as well as education and law, were at a low level in both face-to-face and distance education. The returns to the disciplines of science and engineering were higher in face-to-face education than in distance education. This paper proposes several recommendations. Adults who do not have higher education degrees should invest in distance higher education to obtain considerable monetary returns, particularly in the disciplines with higher returns such as management and economics. China's distance education institutions should improve the quality of teaching in science and engineering education and find ways to provide high-quality experimental teaching practices. At the same time, they should scale back on instruction of literature, as well as education and law.

Pottery making in technology education aims to foster students' practical and creative ability. In a typical pottery making class, students receive the teacher's instruction on the fundamental techniques used in pottery making and have opportunities to practice. It is meaningful to construct an observation-doing-reflection process for students in a pottery making class to promote their learning experience and performance. Therefore, in this study, a Virtual Reality (VR)-based pottery making approach was applied to technology education in a junior high school to examine its effects on students' creativity and learning engagement. A total of 97 seventh graders from three classes participated in pottery making in class. One class of 34 students was assigned to be the experimental group learning with the VR-based approach, while the other two classes were assigned to be the control groups, with 30 students learning with the paper-and-pencil approach and 33 students with the clay-based approach. The results showed that the students learning with the VR-based approach were not only more creative in terms of their products, but also had higher cognitive engagement than those in the control groups. Moreover, the VR-based approach improved the students' behavioral, emotional and social engagement compared to the paper-and-pencil approach.

Low-field nuclear magnetic resonance (LF-NMR) technology plays a growing role in studying reservoirs for oil displacement characteristics. To better explore the reservoir characteristics of Da'anzhai in the Sichuan Province of China, this paper uses LF-NMR imbibition flooding experiments to study the improvement of oil displacement efficiency for shale oil reservoirs in Southwest China by different imbibition flooding technologies. In this article, experiments in scanning electron microscopy, X-ray diffraction analysis, and rock mechanics were conducted to analyze the geological features of the reservoir in the study area. In combination with the test results of the nuclear magnetic resonance method, the field technology has been reformed to improve the oil recovery efficiency. The results show that the Da'anzhai area is mainly composed of interbedded shale and limestone, with a relatively low organic carbon content and low average porosity. The pores shouted are predominantly concentrated in the range of 1–100 nm, and there are micrometer-sized pores. The mineral composition of the area is primarily quartz, dolomite, and calcite, rich in clay minerals. The degree of the development of natural fractures is not high, and the mean coefficient of stress differential in two directions is 0.19. The content of brittle minerals is greater than 50%, meaning that the overall compressibility is good. The results of the stratified T2 test show that the imbibition efficiency of shale in this area is low. The imbibition efficiency of the three cores is the best in 0–20 mm, and the imbibition efficiency is low in the 40–60-mm section. The optimum imbibition formula 2 has an apparent promoting effect on the imbibition of shale in this area. Based on the optimal formula system of imbibition flooding experiments, the average reservoir volume of reconstruction (SRV) in the Sichuan Basin increased from 39 million cubic meters to 46 million cubic meters. The oil production test went from "seeing boiling oil" to almost 2 tons/day, making a significant breakthrough in "oil production." As a result, LF-NMR technology is used to investigate the effects of core imbibition and oil displacement. The results can be used as a guide for applying on-site oil production technology transformation, which is of constructive importance for improving production. [ABSTRACT FROM AUTHOR]

Against the backdrop of an international trend of increased paternal involvement in caregiving and a national setting in which the role of disciplinarian and authoritarian are still centralized, the main aim of the current study is to investigate the paternal masculinities of contemporary Chinese fathers. Based on interviews with 30 urban Chinese fathers, our results reveal that paternal masculinity can be understood in contemporary Chinese society as a hybrid version encompassing caring masculinities, but also aspects of protective masculinity and/or masculine care. Our participants perceived themselves as caring fathers who were physically and emotionally involved in routine caregiving activities and who provided companionship for their children, which embodies the traits of caring masculinity. At the same time, some fathers also emphasized their roles as good providers, whereas others highlighted their roles as gender role models, whilst some stressed all three dimensions. By embracing these different elements simultaneously, urban Chinese fathers both confirm and challenge traditional notions of masculinity, but through enacting this hybrid form of masculinity they perpetuate the system of gender inequality in a new and softer way. The findings from this study expand our understanding of hybrid masculinity and masculine care from a local perspective. [ABSTRACT FROM AUTHOR]

Purpose: Innovation is vital for sustainable regional development. Government is generally not a source of innovation per se, but the authors shows that by establishing and funding an industrial innovation ecosystem, it can create fertile conditions for research institutions to introduce innovative technologies into industry and for industry to introduce its gaps and needs to motivate and direct academic research. This paper aims to present a case study of the Jiangsu Industrial Technology Research Institute (JITRI) as a "triple helix" collaboration model engaging Industry-University-Research (IUR) institutions. The authors aim to provide a fresh perspective on constructing innovation ecosystems, promoting value creation and advancing the adoption of industrial technology. Design/methodology/approach: Taking JITRI as a case study, this research examines its innovative approaches to interfacing with IUR organizations within China's Yangtze Delta region. The authors propose a multilayered framework where JITRI serves as the core, facilitating the formation of a robust innovation ecosystem with diverse IUR entities. Findings: This framework comprises three layers: core, platform and support. JITRI acts as the central nexus, binding these elements together and fostering a cohesive innovation ecosystem. By analyzing the operational mechanisms of the Jiangsu Provincial innovation system, the authors gain valuable insights into how JITRI bridges the gap between academia and industry. This facilitates the efficient commercialization of technologies. The success of the JITRI approach presents a compelling model for emulation by other provincial innovation ecosystems seeking to enhance their innovation capabilities. Research limitations/implications: This study enriches the ongoing conversation on innovation ecosystems, proposing novel avenues for further research. However, the field requires continuous monitoring through longitudinal studies. Given the long-term nature of such initiatives, the full impact of this approach might only be realized over several decades. Practical implications: JITRI aims to create a robust and innovative provincial innovation ecosystem through its focus on IUR collaboration. This unique approach offers valuable insights and ideas for fostering the development of thriving innovation ecosystems in other provinces. These insights encompass new perspectives on innovation ecosystem development, value creation and industrial advancement. Originality/value: This study pioneers the use of the JITRI system as a case study, offering valuable insights with potential application to innovation ecosystems across China and globally. [ABSTRACT FROM AUTHOR]

There is a huge funding gap in the abandoned mines ecological restoration in China. It is of great research value to explore how PPP model can better introduce social capital into the low-profit ecological restoration of abandoned mines. Based on the innovation perspective of the central government's reward and punishment system, this paper constructs an evolutionary game model of "local government-social capital", analyzes the interaction and behavior mechanism of core stakeholders in the operation process of abandoned mines ecological restoration PPP mode, and discusses the influence of evolutionary equilibrium strategy and parameters change on evolutionary strategy under different scenarios by Matlab simulation. The research shows that the abandoned mines ecological restoration needs the support of the central government. When the local government lightly punishes the low-quality service of social capital, the central government needs to pay higher costs to promote all parties to actively participate in the operation and supervision of the PPP project. The revenue and cost of government supervision, the operating subsidy for social capital and the cost saved by social capital in providing bad service are the key factors affecting the evolution of the game between government and social capital. Punishment can effectively spur social capital to keep the contract and operate in the project, but the punishment effect will be ineffective without government supervision. Finally, some suggestions are put forward, such as establishing a long-term supervision mechanism and a reasonable income mechanism for PPP projects, increasing penalties for violations, attracting third parties to reduce supervision costs and strengthening communication between the two parties, so as to make the project take into account the economic performance of social capital and the social welfare of government departments, and achieve dual Pareto improvement. [ABSTRACT FROM AUTHOR]

In recent years, heavy metal contamination of soils has become a major concern in China due to the potential risks involved. To assess environmental pollution and human health risks in a typical heavy metal polluted site in Jiangxi Province, a thorough evaluation of the distribution, pollution levels, and sources of heavy metals in soils of the Yangmeijiang River watershed was conducted in this study. Positive matrix factorization and Monte Carlo simulation were used to evaluate the ecological and human health risks of heavy metals. The research findings indicate that heavy metal pollution was the most severe at the depth of 20–40 cm in soils, with local heavy metal pollution resulting from mining and sewage irrigation. The high-risk area accounted for 91.11% of the total area. However, the pollution level decreased with time due to sampling effects, rainfall, and control measures. Leaf-vegetables and rice were primarily polluted by Cd and Pb. The main four sources of heavy metals in soils were traffic emission, metal smelting, agricultural activities and natural sources, mining extraction, and electroplating industries. Heavy metals with the highest ecological risk and health risk are Cd and As, respectively. The non-carcinogenic and carcinogenic risks of children were 7.0 and 1.7 times higher than those of adults, respectively. Therefore, children are more likely to be influenced by heavy metals compared to adults. The results obtained by the risk assessments may contribute to the identification of specific sources of heavy metals (e.g., traffic emissions, metal smelting, mining excavation, and electroplating industries). Additionally, the environmental impacts and biotoxicity associated with various heavy metals (e.g., Cd and As) can also be reflected. These outcomes may serve as a scientific basis for the pollution monitoring and remediation in the mining-affected areas. [ABSTRACT FROM AUTHOR]

aimaiti,1,* Jiahui Fan,1 Liang Wang,2 Yuanyuan Wang,3 Hu Sun,3 Jie Lv,1 Xiufeng Zhang,4 Jing Wang,4 Xiumin Ma11State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Laboratory Center, Tumor Hospital Affiliated to Xinjiang Medical University, Urumqi, Xinjiang, 830011, People's Republic of China; 2The Fifth Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, 830011, People's Republic of China; 3First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, 830011, People's Republic of China; 4Department of Respiratory Medicine, Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan, 570100, People's Republic of China *These authors contributed equally to this work Correspondence: Xiumin Ma, State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Laboratory Center, Tumor Hospital Affiliated to Xinjiang Medical University, Urumqi, Xinjiang, 830011, People's Republic of China, Email [email protected] Jing Wang, Department of Respiratory Medicine, Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan, 570100, People's Republic of China, Email [email protected] Background: Macrophage play a significant work in the development of tuberculosis. This study aims to investigate the relationship between TREM2 and macrophage polarization, as well as the related cytokines. Methods: This study involved 43 pulmonary tuberculosis patients and 37 healthy controls. Enzyme-linked immunosorbent assay (ELISA) was used to detect the expression levels of M1/M2 macrophage-related cytokines IL-10 and IL-12 in the peripheral blood of pulmonary tuberculosis patients. The relative mRNA expression levels of TREM2, IL-10 and IL-12 were detected using quantitative real-time PCR (qRT-PCR). Additionally, Spearman rank correlation analysis was used to preliminarily assess the correlation between TREM2 and M1 / M2 macrophages. Hematoxylin-eosin (HE) staining was performed to observe the pathological manifestations of pulmonary tuberculosis lesions. Immunohistochemical (IHC) staining was used to observe the localization of the macrophage-specific molecule CD68, the M1 specific molecule iNOS, the M2 specific molecule CD163, and TREM2. Results: The lesions of pulmonary tuberculosis patients showed Langhans multinucleated macrophages and tuberculous granulomas. The ELISA results indicated that the expression levels of IL-10 and IL-12 were significantly increased in peripheral blood of pulmonary tuberculosis patients. Additionally, the relative mRNA expression levels of TREM2, IL-10 and IL-12 were also significantly higher in the pulmonary tuberculosis group. Furthermore, a positive correlation was observed between TREM2 and IL-10, which are secreted by M2 macrophages. IHC revealed significant positivity of TREM2 and macrophage-related markers in tuberculous granuloma. Specifically, TREM2 and M2 macrophage marker CD163 were significantly expressed in the cytoplasm and membrane of Langhans multinucleated macrophages. Conclusion: The role of macrophage polarization in pulmonary tuberculosis is significant, and further investigation is needed to understand relationship between TREM2 and M2 macrophages. [ABSTRACT FROM AUTHOR]

The accounts payable payment period for transportation costs is usually less than the accounts receivable cycle for transportation fees for a third-party logistic (3PL) firm in China; hence, a capital-constrained 3PL firm has a strong demand to seek credit loans from some competitive lenders (e.g., fourth-party logistic [4PL] firm or private lending [PL] organization). To investigate the attractiveness and effectiveness of different financing modes, two practical financing modes (4PL-driven and PL-driven) and an improved 4PL-driven financing mode are formulated in this work. We present a game-theoretical approach to investigate the equilibria based on the profile functions among 4PL firm (or PL), 3PL firm, supplier and retailer under different financing modes. We find that (1) the practical 4PL-driven financing mode will be the Pareto-dominant financing mode for 3PL firms, suppliers and retailers when the initial budget of the 3PL firm falls below a certain level. (2) The 4PL firm's profit is always higher when using the improved 4PL-driven financing mode. (3) The 4PL firm should use the practical 4PL-driven financing mode for start-up 3PL firms to support their growth; but when they grow to a certain scale, the 4PL firm should use the improved 4PL-driven financing mode to enhance its profit. [ABSTRACT FROM AUTHOR]

Studying human behavioral patterns from social media data is an important part of emergency management. However, the multidimensional characteristics of social media data have rarely been fully utilized. This study proposes a multidimensional analytical framework for social media user behavior that integrates time–geographic–semantic features. The framework defines the spatiotemporal semantic multidimensional relationship of social media user behavior and maps it into a time–geographic–semantic (TGS) cube, based on which a TGS‐weighted similarity measure was created. We then applied a spectral clustering algorithm to cluster the trajectories of the user behavior. Subsequently, a prefix‐projected pattern growth algorithm was used to mine frequent semantic patterns from the clustering results and analyze their spatiotemporal distribution characteristics. Taking the COVID‐19 pandemic as a case study, we analyzed Weibo user behavior in China from January 9 to March 10, 2020. The results showed that the clustering of TGS similarity was better than that of the commonly used edit distance on real and longest common subsequences. Five semantic patterns of public responses were identified during the COVID‐19 pandemic. The semantic patterns of categories 1, 2, 4, and 5 were "spindle‐shaped," meaning that their core semantics were stable and concentrated on one or several topics despite the frequent semantic changes in the middle stage. Category 3 was "wave‐shaped," indicating that their semantics fluctuated between serval topics during the pandemic. This discovery shows that the framework is suitable for analyzing and comprehensively understanding public behavior during pandemic emergencies. This framework has good universality and great potential for extension to other emergencies. [ABSTRACT FROM AUTHOR]

The vegetation ecosystem in the southern hilly region of China (SHRC) plays a crucial role in the country's carbon reservoir. Clarifying the dynamics of net primary productivity (NPP) in this area and its response to climate factors in the context of climate change is important for national forest ecology, management, and carbon neutrality efforts. This study, based on remote sensing and meteorological data spanning the period 2001 to 2021, aims to unveil the spatiotemporal patterns of vegetation productivity and climate factors in the southern hilly region, explore interannual variation characteristics of vegetation productivity with altitude, and investigate the response characteristics of NPP to various climate factors. The results indicate that from 2001 to 2021, the annual average NPP in the southern hilly region had a significant increasing trend of 2.13 ± 0.78 g m−2 a−1. The trend of NPP varies significantly with altitude. Despite a general substantial upward trend in vegetation NPP, regions at lower elevations exhibit a faster rate of increase, suggesting a diminishing difference in the NPP of different elevation ranges. The overall rise in average temperature has positive implications for the southern hilly region, while the impact of precipitation on vegetation NPP demonstrates noticeable spatial heterogeneity. Regions in which vegetation NPP is significantly negatively correlated with precipitation are mainly concentrated in the southern areas of Guangdong, Fujian, and Jiangxi provinces. In contrast, other regions further away from the southeastern coast tend to exhibit a positive correlation. Over the past two decades, there has been an asymmetry in the diurnal temperature variation in the SHRC, with the nighttime warming rate being 1.8 times that of the daytime warming rate. The positive impact of daytime warming on NPP of vegetation is more pronounced than the impact of nighttime temperature changes. Understanding the spatiotemporal patterns of NPP in the SHRC and the characteristics of its response to climate factors contributes to enhancing our ability to protect and manage vegetation resources amidst the challenges of global climate change. [ABSTRACT FROM AUTHOR]

Understanding the relationship between city size and resilience is crucial for informed decisions on preparedness and interventions in building resilient cities. This study addresses this issue by dividing urban resilience into four components: stability, redundancy, resourcefulness, and connectivity. Using the above evaluation framework, we assessed the spatial–temporal variations in the relationship between city size and resilience in the Yangtze River Economic Belt from 2005 to 2020. The findings shows that, overall, resilience increased in the cities, with larger populations and spatial scales showing greater resilience, but both megacities and small cities experienced a decline in resilience. In terms of the four components of resilience, most of the region's cities have roughly equal connectivity and stability, but redundancy and resourcefulness vary by city size and location. Specifically, downstream and larger cities demonstrated better crisis resolution and innovation. The dominant coupling coordination states showed antagonism between population and resilience. Upstream areas experienced a mismatch between "low resilience" and "large population", while a moderate coordination existed between spatial scale and resilience. Further, it was found that factors hindering urban resilience varied according to city size. Cities with a population of <3 million faced low connectivity and limited transformation capacity. Those with a population of 3–5 million had moderate connectivity limitations, while cities with a population >5 million faced energy and aging population challenges. This study contributes to urban resilience discourse by providing a conceptual understanding and empirical analysis of the impact of city size on resilience. [ABSTRACT FROM AUTHOR]

Due to the relatively brief domestication history of sugar beet (Beta vulgaris ssp. vulgaris), our understanding of the genomic diversity and functional genes in its cultivars is limited, resulting in slow breeding progress. To address this issue, a total of 306 germplasm materials of major cultivars and breeding lines from China, the USA, and Europe were selected for genome resequencing. We investigated population structure and genetic diversity and performed selective scanning of genomic regions, identifying six novel genes associated with important agronomic traits: the candidate genes DFAX2 and P5CS for skin roughness; the candidate genes FRO5, GL24, and PPR91 for root yield and sugar yield, and the pleiotropic candidate gene POLX for flourishing growth vigour, plant height, crown size, flesh coarseness, and sugar yield. In addition, we constructed a protein–protein interaction network map and a phenotype-gene network map, which provide valuable information for identifying and characterizing functional genes affecting agronomic traits in sugar beet. Overall, our study sheds light on the future improvement of sugar beet agronomic traits at the molecular level. [ABSTRACT FROM AUTHOR]

Host‐associated microbiota can significantly impact host fitness. Therefore, naturally occurring variations in microbiota may influence the health and persistence of their hosts. This finding is particularly important in reintroduced animals, as they typically experience habitat changes during translocations. However, little is known about how microbiomes are altered in response to conservation translocation. Here, we accessed the gut microbiome of Przewalski's horse (Equus przewalskii) populations in China from three nature reserves (i.e. Xinjiang Kalamaili Nature Reserve, KNR; Dunhuang Xihu National Nature Reserve, DXNNR; and Anxi Extreme‐arid Desert Nature Reserve, AENR) using 16s rRNA gene and metagenome sequencing. The results showed that the microbial composition and function differed significantly across locations, while a subset of core taxa was consistently present in most of the samples. The abundance of genes encoding microbe‐produced enzymes involved in the metabolism of carbohydrates, especially for glycoside hydrolases, was significantly higher in open‐spaced KNR populations than in more confined AENR individuals. This study offers detailed and significant differential characters related to the microbial community and metabolic pathways in various reintroduced sites of Przewalski's horse, which might provide a basis for future microecological and conservation research on endangered reintroduced animals. [ABSTRACT FROM AUTHOR]

China's argillaceous limestone reservoir has a lot of oil and gas resources, and hydraulic fracturing of the argillaceous limestone reservoir faces many difficulties. The first problem is that the heterogeneity of the argillaceous limestone reservoir is strong, and it is difficult to optimize fracturing parameters. The second problem is that there are a lot of natural fractures in the argillaceous limestone reservoir, which leads to a lot of fracturing fluid loss. The third problem is that the closure pressure of the argillaceous limestone reservoir is high, and the conductivity of fractures decreases rapidly under high closure pressure. The last problem is that the fracture shape of the argillaceous limestone reservoir is complex, and the law of proppant migration is unclear. The main research methods in this paper include reservoir numerical simulation, fluid-loss-reducer performance evaluation, flow conductivity tests and proppant migration visualization. To solve the above problems, this paper establishes the fracturing productivity prediction model of complex lithology reservoirs and defines the optimal hydraulic fracturing parameters of the argillous limestone reservoir in the Sichuan Basin. The 70/140 mesh ceramide was selected as the fluid loss additive after an evaluation of the sealing properties of different mesh ceramides. At the same time, the hydraulic fracture conductivity test is carried out in this paper, and it is confirmed that the fracture conductivity of 70/140 mesh and 40/70 mesh composite particle-size ceramics mixed according to the mass ratio of 5:5 is the highest. When the closure pressure is 40 MPa, the conductivity of a mixture of 70/140 mesh ceramic and 40/70 mesh ceramic is 35.6% higher than that of a mixture of 70/140 mesh ceramic and 30/50 mesh ceramic. The proppant migration visualization device is used to evaluate the morphology of the sand dike formed by the ceramsite, and it is clear that the shape of the sand dike is the best when the mass ratio of 70/140 mesh ceramsite and 40/70 mesh ceramsite is 6:4. The research results achieved a good stimulation effect in the SC1 well. The daily oil production of the SC1 well is 20 t, and the monitoring results of the wide-area electromagnetic method show that the fracturing fracture length of the SC1 well is up to 129 m. [ABSTRACT FROM AUTHOR]

Objective: This study aims to explore the relationship between age and whether the percentage of total weight loss (TWL%) is ≥ 25% or not at 1 year after bariatric surgery (BS). We aimed to provide evidence for the stratified treatment of spatients with obesity at different ages. Methods: The primary outcome evaluated was whether TWL% was no less than 25% at 1 year after BS. A TWL% ≥ 25% was defined as a satisfied TWL% outcome. Logistic regression analysis and the restricted cubic spline (RCS) function were used to analyze the relationship between age and the satisfied TWL% outcome at 1 year after BS. Results: Two hundred and ninety-one patients were included in our study. After adjusting for potential confounders, the odds ratios (ORs) of the corresponding quartiles of age associated with satisfied TWL% outcome were 1.00 (reference), 1.117 [95% confidence interval (95% CI) = 0.540–2.311], 1.378 (95% CI = 0.647–2.935), and 0.406 (95% CI = 0.184–0.895). RCS analysis revealed a non-linear inverted L-shaped association between age and satisfied TWL% outcome at 1 year after BS (non-linear P = 0.033). Conclusion: Age was an independent predictor of satisfied TWL% outcome one year following BS, and our study considered 32 years as a potential cut-off point. For Chinese patients over the age of 32 who are eligible for BS, it may be beneficial to do BS earlier as the probability of achieving a satisfied TWL% outcome may decrease with age. [ABSTRACT FROM AUTHOR]

Background: Immune thrombocytopenia (ITP) is an autoimmune hemorrhagic disease characterized by low platelet count and bleeding manifestations. However, some patients also suffered from atherosclerosis or even infarction. Apart from activated platelets, lipid metabolism takes a large part in the formation of atherosclerosis and metabolic syndrome. The lipid metabolic state in ITP patients is still unknown. Methods: We retrospectively reviewed 302 hospitalized ITP patients in our cohort, comparing their blood lipids, bleeding symptoms, metabolic diseases and treatment responses. Results: We found a high proportion of ITP patients suffered from hyperlipidemia, and other metabolic diseases including cardiovascular or cerebral atherosclerosis or infarction, hypertension, and type 2 diabetes. Hyperlipidemia was associated with severe bleeding and treatment refractoriness in ITP. Statins could alleviate thrombocytopenia and bleeding severity, and facilitate ITP treatment, while improving hyperlipidemia in ITP patients. Conclusions: Our present study demonstrated that lipid metabolism might play an indispensable role in ITP pathogenesis and development. [ABSTRACT FROM AUTHOR]

The way in which business ethics change over time will remain theoretically unclear unless we empirically reveal the temporal coevolution and coalignment among a changing environment, transitional institutions, strategic adaptations, and performance implications. To revitalize this coevolutionary perspective in business ethics research, in this special issue, we ask the following question: how do business ethics practices coevolve with a changing society and technology advancement as a result of the strategic choices of organizations in adapting to and shaping the environment? This special issue includes a collection of seven empirical studies of business ethics in China that differ in methodology and empirical context but collectively showcase the change in business ethics practices in an emerging economy and the processes underlying this change. Based upon the findings, we propose a conceptual model of the coevolution among business ethics practices, technological innovation, institutional transition and disruptive events; then, we pose questions for future research. [ABSTRACT FROM AUTHOR]

The global total amount of generated solid waste is currently on a rapid growth trend. China, as the largest developing country, promulgated its Pilot Work Plan for the Construction of Zero-Waste Cities led by the new development concept in 2018 after recognizing the inadequacy and urgency of solid waste management, and the lack of valuable experience and benchmark cities for the construction of zero-waste cities. This study uses the undesirable super-efficiency model and kernel density estimation method to measure the efficiency of zero-waste city construction in 16 prefecture-level cities in Shandong Province and analyze their spatial and temporal differences. Three major problems were found, namely, low regional coordination, the rigid policies of some local governments, and the unbalanced development of scale efficiency and pure technical efficiency. Results show that the zero-waste city construction efficiency as a whole shows a declining and then fluctuating growth trend, and that low-scale efficiency is the main reason behind the decrease in construction efficiency. Suggestions are then provided considering three aspects: improving regional synergy; improving government quality and capacity, and strengthening government supervision and revitalizing the market; and introducing social capital for environmental pollution treatment. These suggestions ultimately help improve the level of zero-waste city construction. [ABSTRACT FROM AUTHOR]

This paper adopts principal component analysis to assign weights to three fund performances obtained independently by the Sharpe index, Jensen index, and Treynor index. Therefore, a comprehensive model for the performance of Chinese securities investment funds (SIFs) is derived by combining these three indexes. The empirical study shows that the regression between SIFs managers' characteristics and fund performance is better when using this comprehensive measurement model. Moreover, SIFs managers' experience and tenure have negative and positive effects on fund performance, respectively. However, their gender, education level, professional qualification holdings, research experience, and abroad experience, do not significantly influence the fund performance. [ABSTRACT FROM AUTHOR]

Objective: To evaluate electroencephalography (EEG) microstate differences between patients with migraine with aura (MWA), patients with migraine without aura (MWoA), and healthy controls (HC). Background: Previous research employing microstate analysis found unique microstate alterations in patients with MWoA; however, it is uncertain how microstates appear in patients with MWA. Methods: This study was conducted at the Headache Clinic of the First Affiliated Hospital of Xi'an Jiaotong University. In total, 30 patients with MWA, 30 with MWoA, and 30 HC were enrolled in this cross‐sectional study. An EEG was recorded for all participants under resting state. The microstate parameters of four widely recognized microstate classes A–D were calculated and compared across the three groups. Results: The occurrence of microstate B (MsB) in the MWoA group was significantly higher than in the HC (p = 0.006, Cohen's d = 0.72) and MWA (p = 0.016, Cohen's d = 0.57) groups, while the contribution of MsB was significantly increased in the MWoA group compared to the HC group (p = 0.016, Cohen's d = 0.64). Microstate A (MsA) displayed a longer duration in the MWA group compared to the MWoA group (p = 0.007, Cohen's d = 0.69). Furthermore, the transition probability between MsB and microstate D was significantly increased in the MWoA group compared to the HC group (p = 0.009, Cohen's d = 0.68 for B to D; p = 0.007, Cohen's d = 0.71 for D to B). Finally, the occurrence and contribution of MsB were positively related to headache characteristics in the MWoA group but negatively in the MWA group, whereas the duration of MsA was positively related to the visual analog scale in the MWA group (all p < 0.05). Conclusions: Patients with MWA and MWoA have altered microstate dynamics, indicating that resting‐state brain network disorders may play a role in migraine pathogenesis. Microstate parameters may have the potential to aid clinical management, which needs to be investigated further. [ABSTRACT FROM AUTHOR]

Prostate cancer morbidity and mortality are increasing globally and in China, and the rate of metastasis is also rising, limiting the therapeutic effect and clinical prognosis of prostate cancer. CD151 is considered to be the first promoter of tumor metastasis in the tetraspanin superfamily. Previous research has linked CD151 to the progression of a number of malignancies, including prostate cancer. However, a recent study found that CD151 can inhibit the progression of prostate cancer. As a result, this paper examines existing research on CD151 and prostate cancer progression in order to clarify the relationship and provide a possible reference for future studies. [ABSTRACT FROM AUTHOR]

Purpose: Viewing the domestic downside risk as a "pushing" factor for outward foreign direct investment (OFDI), this study aims to examine the surge in Chinese cross-border acquisitions (CBAs) between 2008 and 2017, a unique window when private firms in China were allowed to conduct CBAs. Design/methodology/approach: This study examines the effect of down-side risk on cross-border acquisition performance by using the sample of Chinese A-share listed companies from 2008 to 2017. Specifically, this study considers three kinds of systemic risk, systematic risk and idiosyncratic risk, and respectively examines their impact on CBAs activities; this study also investigates their subsequent results after CBAs activities. The contingency effect of state ownership on the above relationship is also discussed. Findings: The findings reveal that pre-CBA systemic risk explains the volume of CBA activities; CBAs are followed by a reduction in systemic risk; the interactions between systemic risk and CBAs decrease with the level of state ownership; and the above results do not hold for traditional risk measures (i.e. systematic risk and idiosyncratic risk). Originality/value: This study contributes to the literature by revealing the role of systemic risk as a "pushing" factor in the context of OFDI and suggesting an alternative explanation for CBAs from China: Chinese firms (especially private firms) took advantage of the rare opportunity between 2008 and 2017 given by the government to transfer assets overseas through CBA. [ABSTRACT FROM AUTHOR]

The environmental, social, and governance (ESG) performance is a vital pursuit of firms' strategy and has caused substantial influences on firms' behavior and outcomes. Therefore, exploring how to facilitate the firms' ESG performance is necessary. This paper examines the role of CEOs' hometown identity in facilitating firm's ESG performance. Based on a sample of Chinese listed firms during 2010–2018, we compare the ESG performance of firms with hometown CEO with that of firms without hometown CEO and find that CEOs' hometown identity is associated with significantly higher ESG performance. The benchmark results still hold after instrumental variable regression, placebo test, propensity score matching, lagging, and altering the measurement of CEOs' hometown identity. Additional analysis shows that CEOs' hometown identity exerts a more prominent positive effect on ESG performance among firms with higher financing constraints and SOEs. Our findings reveal a bright side of CEOs' hometown identity: it facilitates ESG performance. Therefore, this paper's conclusion sheds new light on the bright side of CEOs' hometown identity from the perspective of firms' ESG performance and provides insights into how to improve ESG performance. [ABSTRACT FROM AUTHOR]

Purpose: The authors investigate how logistics digitalization affects two types of third-party logistics (3PL) performance: financial performance and service performance. In particular, the authors explore the mediating role of customer collaboration between logistics digitalization and firm performance based on organizational information processing theory and examine the moderating role of government support. Design/methodology/approach: The authors use an SPSS macro program (PROCESS regression analysis) to analyze survey data from 235 3PL firms in China. The mediation model, moderation model and moderated mediation model are tested. Findings: The empirical results show that in the new age of digitalization transformation, logistics digitalization positively affects 3PL's financial performance and service performance by strengthening customer collaboration. Additionally, government support amplifies the positive effect of customer collaboration on service performance but not financial performance. The moderated mediation test further indicates that government support strengthens the positive indirect effect of digitalization on service performance through customer collaboration. Originality/value: This study offers empirical insights into the growing body of 3PL literature, and the findings contribute to the theoretical and practical understanding of the emerging research topic of digital transformation (DT) and sustainability issues in 3PL firms. [ABSTRACT FROM AUTHOR]

Integration with client firms is the most important external relationship for third-party logistics (3PL) firms. Based on information processing theory, a conceptual model was developed to explore the mechanism of how customer integration contributes to 3PL firms' performance via differentiation and low-cost advantages, and the moderating effects of information technologies were examined in relation to the trend of digital transformation. Survey data were collected from 235 3PL firms in China and analysed using structural equation modelling. The results show that customer integration is positively related to the performance of 3PL firms, which is mediated by differentiation and low-cost advantages. In addition, information acquisition technologies and information processing technologies significantly moderate the effect of customer integration on differentiation advantages. These findings help to address the challenges faced by 3PL firms in the context of digital transformation and add to the literature on customer integration and logistics information technologies. [ABSTRACT FROM AUTHOR]

In all educational contexts, technological developments and changes in pedagogical theory mean that any picture of current practice and attitudes must be dynamic. In many countries, the learning outcomes of foreign language courses now include intercultural communicative competence (ICC), although the precise model for teaching ICC varies even across the English-speaking world. Internet-mediated approaches are widely used to support intercultural learning. In China, the geographical scale of the country and the speed and extent of contemporary socio-economic evolution, allied to long-established and distinctive cultures of learning, make the interface of new technologies and intercultural learning objectives particularly interesting and significant. A small-scale study of college teachers' and learners' perceptions of intercultural classroom instruction, with a special focus on Internet mediation, was conducted in mid-2007, using questionnaires and semi-structured questions, to explore the professional, personal and technical issues associated with Internet-mediated learning of languages and cultures. The results show that textbooks remain the predominant authority, while Internet tools are used as a source of information rather than a means of communication. Findings suggest recognition by teachers and students of the potential of the medium, and of the validity of intercultural goals for foreign language classes, although there are some divergences between the views of teachers and students. However, it is suggested that national policy, local incentives and resources and above all educational traditions do not yet allow optimal use of Internet-mediated approaches.

China's construction industry confronts with the dilemma of carbon emissions in adjusting the environmental regulations. Many studies are neglected on discovering the potential nexus amongst environmental regulations (ERs), technological innovation (TI) and CEI (CEI) and ignores the relationships amongst TI for reducing CEI. To mitigate this gap, this study bridges institutional theory to integrate the practices in the construction industry. This study applies a panel dataset on the construction industry from 30 provinces during 2004–2018 and uses it with a two-step system-generalised method of moments for analysis. The proposed method enables the prevention of the interference of the heteroscedasticity problem and improves certain analytical efficiency. The results are as a guideline for policymakers in rechecking the policies and regulations adequacy. The findings indicate that (1) the forced emission reduction effect is proven by command-and-control and market-based ERs, which can inhibit CEI; (2) voluntary ERs have an inverted U-shaped nexus with CEI; in other words, the green paradox effect shifts to the forced emission reduction effect once the intensity of voluntary ERs increases; and (3) market-based and voluntary ERs reduce CEI effectively by using TI as the mediator in construction industry. [ABSTRACT FROM AUTHOR]

This paper explores the influence of fund managers' social networks on the herding behavior of securities investment funds (SIFs) in China. Using the data of Chinese SIFs in recent years as a sample, it adopts the CSAD model to measure SIFs' herding behavior. Combining indicators such as social network centrality, constraint, and size, it constructs a regression model of the influence of fund managers' social networks on the herding behavior of SIFs and conducts an empirical study. The heterogeneity of this influence is investigated in four dimensions, degree of herding behavior, gender, diploma, and region. The results show that: (i) The larger the social network size of fund managers, the lower the degree of herding behavior of fund managers, but the effect of the network constraint on the degree of herding behavior is not significant. (ii) When the degree of herding behavior of SIFs is high, the effect of network size on herding behavior is heterogeneous. (iii) The relationship between the social network of male fund managers and the degree of herding behavior is more significant than that of female fund managers, as network size is significant for male fund managers, while the regression results of social network centrality, network constraint, network size, and the degree of herding behavior of female fund managers are all not significant. (iv) The social network of the fund manager with a master's degree has a significant impact on the herding behavior of SIFs, which is not significant in fund managers with Ph.D. [ABSTRACT FROM AUTHOR]

Industry dominates energy consumption and carbon emissions in China, and industrial energy efficiency is critical for the achievement of energy transformation and carbon emission reduction. With the rapid development of the digital economy, its impact on energy efficiency is gradually emerging, and it is necessary to clarify the influencing mechanism on industrial energy efficiency. Based on the panel data of industrial sectors in 41 cities in the Yangtze River Delta from 2011 to 2019, the main objectives of this study are to more accurately measure the industrial total factor energy efficiency in each city by using the Super-Dynamic-SBM model. It analyses the influence mechanism of the digital economy and other influencing factors on industrial total factor energy efficiency with different methods. The research results indicate that, first, the total factor energy efficiency of the industrial sector in the Yangtze River Delta urban agglomeration generally showed a steady upward trend. Second, the digital economy and environmental regulation play a significant role in promoting total factor energy efficiency. In addition, industrial energy efficiency and the digital economy show an inverted "U" shaped relationship. With the improvement of the digital economy, its marginal contribution to total factor energy efficiency gradually weakens. Finally, technological progress is an important transmission channel for the impact of the digital economy on total factor energy efficiency. [ABSTRACT FROM AUTHOR]

A series of ecological restoration programmes (ERPs) have been implemented in the Qinghai‐Tibet Plateau to reverse ecological deterioration. However, the multiple ecological benefits of these ERPs and their driving factors remain unclear. This study analyzed the dynamic changes in fractional vegetation cover (FVC), ecosystem services [water yield (WY), net primary productivity (NPP), and soil conservation (SC)], and sustainable development goals (SDGs) in the Forest Protection and Construction Programme (FPCP), Grassland Protection and Construction Programme (GPCP), Sandy Land Control Programme (SLCP), and Soil Erosion Control Programme (SECP) in the Qinghai‐Tibet Plateau from 2000 to 2015. The geographically weighted regression model was used to reveal the spatial differences of drivers of various ecological benefits. The results showed that ecological benefits increased synergistically in the GPCP and SLCP, while trade‐offs between NPP and WY were observed for the FPCP and SECP. ERPs resulted in a significant increase (p < 0.05) in FVC, SDG 15.1.1, and SDG 15.3.1 and a significant decrease (p < 0.01) in SDG 15.4.2, except for the SLCP. ERPs improved the FVC, WY, and SC, but did not reverse grassland degradation. The ecological benefits of the FPCP and SLCP were poor after 2010, while the ecological benefits of the SLCP have been better since 2012. FVC and WY were dominated by precipitation, and NPP was dominated by FVC. Slope dominated SC in the GPCP, SECP, and SLCP, while precipitation dominated SC in the FPCP. This study can provide scientific support for sustainable vegetation management. [ABSTRACT FROM AUTHOR]

Due to the national dynamic zero-COVID strategy in China, there were no persistent local transmissions of SARS-CoV-2 in Beijing before December, 2022. However, imported cases have been frequently detected over the past 3 years. With soaring growth in the number of COVID-19 cases in China recently, there are concerns that there might be an emergence of novel SARS-CoV-2 variants. Routine surveillance of viral genomes has been carried out in Beijing over the last 3 years. Spatiotemporal analyses of recent viral genome sequences compared with that of global pooled and local data are crucial for the global response to the ongoing COVID-19 pandemic. We routinely collected respiratory samples covering both imported and local cases in Beijing for the last 3 years (of which the present study pertains to samples collected between January and December, 2022), and then randomly selected samples for analysis. Next-generation sequencing was used to generate the SARS-CoV-2 genomes. Phylogenetic and population dynamic analyses were performed using high-quality complete sequences in this study. We obtained a total of 2994 complete SARS-CoV-2 genome sequences in this study, among which 2881 were high quality and were used for further analysis. From Nov 14 to Dec 20, we sequenced 413 new samples, including 350 local cases and 63 imported cases. All of these genomes belong to the existing 123 Pango lineages, showing there are no persistently dominant variants or novel lineages. Nevertheless, BA.5.2 and BF.7 are currently dominant in Beijing, accounting for 90% of local cases since Nov 14 (315 of 350 local cases sequenced in this study). The effective population size for both BA.5.2 and BF.7 in Beijing increased after Nov 14, 2022. The co-circulation of BF.7 and BA.5.2 has been present in the current outbreak since Nov 14, 2022 in Beijing, and there is no evidence that novel variants emerged. Although our data were only from Beijing, the results could be considered a snapshot of China, due to the frequent population exchange and the presence of circulating strains with high transmissibility. National Key Research and Development Program of China and Strategic Priority Research Program of the Chinese Academy of Sciences. For the Chinese translation of the abstract see Supplementary Materials section. [ABSTRACT FROM AUTHOR]

The Cuiguan pear is called "June snow" and the skin is thin; the meat is crisp and juicy; the taste is thick and fresh; and the juice is rich and sweet. In this study, the volatile organic compounds and the sensory and physicochemical parameters of the Cuiguan pear from four different regions of China (Sichuan (SC), Shangdong (SD), Chongming (CM), Zhuanghang (ZH)) were assessed. The highest differences in the physicochemical parameters were observed between four regions. The volatile fingerprints of GC-IMS showed great differences in the volatile of the Cuiguan pear, which suggested that the aroma of pears could be largely impacted by origin areas. (E)-ethyl-2-hexenoate can be used to distinguish between the 'CM' and pears from other regions. High contents of 2-heptanone, 1-pentanol, 1-butanol, 3-methylbutanol, butyl 2-methylbutanoate, heptyl acetate and butyl acetate were observed in the 'SD'. Dimethyl trisulfide, 6-methyl-5-hepten-2-one, 3-hydroxy-2-butanone, 1-penten-3-one, beta-pinene, γ-terpinene, propanal, (e)-2-pentenal, (e)-2-heptenal, 1-pentanol and 3-methyl-1-pentanol were primarily contained in the 'ZH'. Principal component analysis showed that there was very good discrimination based on the information obtained from GC-IMS for four samples. These findings were in agreement with the sensory analysis. In the opinion of the respondents to the consumer test, 'ZH' resulted in the most appreciated sample based on the average scores of the acceptability. This study provides some reference for the development and utilization of the Cuiguan pear. [ABSTRACT FROM AUTHOR]

Background: Primary ocular adnexal extranodal marginal zone mucosa‐associated lymphoid tissue lymphoma (OAML) is a rare subtype of non‐Hodgkin's lymphoma, and no consensus has been defined concerning the optimal treatment strategies. This study aims to investigate the associations of disease characteristics and different treatments with long‐term outcomes of patients with localized OAML. Methods: A large retrospective cohort study was conducted in a single‐center of China, and 166 patients with newly diagnosed primary localized OAML were enrolled. Detailed data of disease characteristics at diagnosis and treatments were collected for all patients. We compared treatment response and progression‐free survival (PFS) among patients with different characteristics and treatments. Results: Of the 166 patients, 52 received complete resection of neoplasm, whereas 114 had residual lesion after surgery. Among the 114 patients, 61 underwent watchful waiting and 53 received further treatment including localized radiotherapy, chemotherapy, or combined radiotherapy and chemotherapy. Median follow‐up was 49 months. A total of 31 patients had disease progression or relapse, including four patients with such event more than five years after initial treatment. The 5‐year PFS was 73.9%, 70.6%, and 85.9%, whereas the 10‐year PFS was 69.3%, 59.2%, and 79.3%, among patients with complete resection of neoplasm, patients in the watchful waiting group and patients with further treatment, respectively. Patients with further treatment had longer PFS, compared with patients in the watchful waiting group (p = 0.011). Bilateral involvement at diagnosis was associated with significantly inferior PFS (p = 0.029), whereas age, IPI score, or TNM staging were not associated with PFS. No serious adverse reaction was reported among patients with further treatment. Conclusions: Bilateral involvement was associated with poor prognosis. Among patients with residual lesions after surgery, further treatment was associated with improved survival. Patients with OAML might experience disease progression or relapse more than five years after initial treatment. [ABSTRACT FROM AUTHOR]

Background: Erythrocyte parameter analysis is the important means for diagnosis and treatment of hematological diseases, which are essential for screening of thalassemia in southern China combined with hemoglobin electrophoresis analysis. But little is known regarding the reference intervals (RIs) in healthy pediatrics in these two areas. Methods: 95% RIs of erythrocyte parameters were calculated from 853 healthy preschoolers, aged from 1 days to <6 years, according to the C28‐A3C guidelines of the Institute of Clinical and Laboratory Standards. To express the magnitude of sex and age variation, standard deviation ratio (SDR) was calculated using ANOVA. Concurrently, we selected 3814 thalassemia carriers as carriers group and drew receiver operating characteristic (ROC) curves to establish the optimal cut‐off values of hemoglobin electrophoresis parameters, which were used as the upper/lower limits of RIs to efficiently screen thalassemia. Results: All parameters except red blood cell (RBC) required age partitioning, confirmed by SDRage above.4. There was no need for sex partitioning on all parameters, confirmed by SDRsex below.4. The optimal cut‐off value of Hemoglobin A2 (Hb A2) in the four subgroups was <7.8% (Hb A), 2.3%–3.2%, 2.5%–3.6% and 2.6%–3.6%, respectively. Conclusion: In this study, the establishment of RIs improved the diagnostic efficiency of hematological disease (especially thalassaemia) for children in Guangxi. It provides reliable hematological references for the identification and diagnosis, treatment monitoring, and health screening of children's clinical diseases. [ABSTRACT FROM AUTHOR]

Binhai New Area (BHNA), as one of the most economically and industrially regions in the Haihe River Basin, China, is seriously affected by seawater intrusion and groundwater over-exploitation. Groundwater vulnerability assessment (GVA) is an effective tool to protect the groundwater resources from being polluted. In this study, vertical and horizontal groundwater conditional factors were first assessed separately by two different models. The AHP-DRASTIC model was used to evaluate the intrinsic groundwater vulnerability and the AHP-GALDIT model was used to evaluate the specific groundwater vulnerability to seawater intrusion. Then, a GIS-based overlaying approach was used to get the comprehensive shallow groundwater vulnerability. The results of the comprehensive model showed that the vulnerability areas of very low, low, medium, and high account for 1.37%, 11.36%, 60.56%, and 26.71%, respectively. Finally, to effectively manage the groundwater in the study area, two remediation areas, two control areas, and one protected area were determined based on the comprehensive groundwater vulnerability maps. This study can not only promote the development of rational exploitation of shallow groundwater and prevention of groundwater pollution in BHNA but also provide a framework for future research in the GVA on the coast. [ABSTRACT FROM AUTHOR]

The performance of ambulance crew affects the quality of pre-hospital treatment, which is vital to the survival for out-of-hospital cardiac arrest (OHCA) patients, yet remains suboptimal in China. In this retrospective analysis study, we aimed to examine the effect of a citywide quality improvement programme on provision of prehospital advanced life support (ALS) by emergency medical service (EMS) system. EMS-treated adult OHCA patients after the implementation of the programme (1 January 2021 to 30 June 2022) were compared with historical controls (1 June 2019 to 31 August 2020) in Suzhou. Multivariable logistic regression analysis and propensity score matching procedures were applied to compare the outcomes between two periods for total OHCA cases and subgroup of cases treated by fixed or non-fixed ambulance crews. A total of 1465 patients (pre-period/post-period: 610/855) were included. In the 1:1 matched analysis of 591 cases for each period, significant improvement (p < 0.05) was observed for the proportion of intravenous (IV) access (23.4% vs. 68.2%), advanced airway management (49.2% vs. 57.0%), and return of spontaneous circulation (ROSC) at handover (5.4% vs. 9.0%). The fixed ambulance crews performed better than non-fixed group in IV access and advanced airway management for both periods. There were significant increases in IV access (AOR 12.66, 95%CI 9.02–18.10, p < 0.001), advanced airway management (AOR 1.67, 95% CI 1.30–2.16, p < 0.001) and ROSC at handover (AOR 2.37, 95%CI 1.38–4.23, p = 0.002) after intervention in unfixed group, while no significant improvement was observed in fixed group except for IV access (AOR 7.65, 95%CI 9.02–18.10, p < 0.001). In conclusion, the quality improvement program was positively associated with the provision of prehospital ALS interventions and prehospital ROSC following OHCA. The fixed ambulance crews performed better in critical care provision and prehospital outcome, yet increased protocol adherence and targeted training could fill the underperformance of non-fixed crews efficaciously. [ABSTRACT FROM AUTHOR]

Landslide susceptibility mapping (LSM) is an important decision basis for regional landslide hazard risk management, territorial spatial planning and landslide decision making. The current convolutional neural network (CNN)-based landslide susceptibility mapping models do not adequately take into account the spatial nature of texture features, and vision transformer (ViT)-based LSM models have high requirements for the amount of training data. In this study, we overcome the shortcomings of CNN and ViT by fusing these two deep learning models (bottleneck transformer network (BoTNet) and convolutional vision transformer network (ConViT)), and the fused model was used to predict the probability of landslide occurrence. First, we integrated historical landslide data and landslide evaluation factors and analysed whether there was covariance in the landslide evaluation factors. Then, the testing accuracy and generalisation ability of the CNN, ViT, BoTNet and ConViT models were compared and analysed. Finally, four landslide susceptibility mapping models were used to predict the probability of landslide occurrence in Pingwu County, Sichuan Province, China. Among them, BoTNet and ConViT had the highest accuracy, both at 87.78%, an improvement of 1.11% compared to a single model, while ConViT had the highest F1-socre at 87.64%, an improvement of 1.28% compared to a single model. The results indicate that the fusion model of CNN and ViT has better LSM performance than the single model. Meanwhile, the evaluation results of this study can be used as one of the basic tools for landslide hazard risk quantification and disaster prevention in Pingwu County. [ABSTRACT FROM AUTHOR]

Background: Unreasonable use of antibiotics and probiotics can alter the gut ecology, leading to antibiotic resistance and suboptimal health outcomes during early life. Our study aims are to clarify the association among antibiotic and probiotic exposure in early life, the microecology of the gut microbiota, and the development of antibiotic resistance; to investigate the long-term impact of antibiotics and probiotics on the health outcomes of infants and young children; and to provide a theoretical basis for the rational use of antibiotics and probiotics from a life course perspective. Methods: The study is a prospective, longitudinal birth cohort study conducted in Shaanxi Province, China from 2018 to 2024. A total of 3,000 eligible mother–child pairs will be enrolled from rural, suburban, and urban areas. The recruitment of the participants begins at pregnancy, and the newborns will be followed up for 2 years at successive timepoints: within 3 days after birth, 42 days after birth, and at 3, 6, 12, 18, and 24 months of age. Sociodemographic data, environmental exposures, dietary patterns, psychological conditions, and medical and drug histories are collected. Cognitive and behavioural development among infants and young children and questionnaires on antibiotic knowledge and behaviour among caregivers will be collected at 12 and 24 months of age. The faecal samples are collected and analysed by 16S rRNA high-throughput sequencing and quantitative PCR (qPCR) for antibiotic resistance genes. Discussion: The findings will inform antibiotic and probiotic use for pregnant women and infants and contribute to establishing rational use strategies of antibiotics and probiotics for paediatricians, health practitioners, and drug administration policy-makers. Trial registration: The study was registered on the Chinese Clinical Trial Registry (ChiCTR) platform, http://www.chictr.org.cn (Record ID: ChiCTR2100047531, June 20, 2021). [ABSTRACT FROM AUTHOR]

Although the energy structure has been gradually enriched in recent years, China, as the world's largest producer and consumer of coal, still accounts for more than 50% of resources. Therefore, in this paper, the high carbon fly ash raw ash (HCFARA) was mechanically activated, and the flotation was treated to obtain decarburized fly ash (DFA) with a loss on ignition of 1.18%, water demand ratio of 101% and strength activity coefficient of 74.5%. With the exception of for water demand ratio, the rest meet the national requirements for the use of Class I fly ash. The foam concrete was prepared by partially replacing cement with decarburized fly ash in different proportions and at different water-to-cement ratios (0.3, 0.4 and 0.5) in order to study its dry density, porosity, compressive strength and thermal conductivity. The results show that the porosity of foam concrete grows with the increase in water-to-cement ratio and fly ash replacement rate. In addition, the dry density and thermal conductivity of the prepared foam concrete can meet the requirements of A05 grade foam concrete (Density less than 500 kg/m3, thermal conductivity less than 0.12 W/(m·k)). The compressive strength can meet the requirements of C0.3 grade foam concrete (Minimum use standard). [ABSTRACT FROM AUTHOR]

Objectives. This study aimed to analyze the clinical features, antibiotic susceptibility profiles, and outcomes of patients with invasive pneumococcal disease (IPD) at a hospital in Ningxia Hui Autonomous Region, to provide the basis for improving the clinical treatment effect. Methods. Patients with IPD were retrospectively collected from 2013 to 2021. Clinical manifestations, laboratory tests, antimicrobial susceptibility, antibiotic treatment, and outcomes of the disease were analyzed. Results. In this study, we identified 127 IPD cases, of whom 49 (38.6%) had meningitis and 78 (61.4%) had bacteremia. The median ages of pediatric cases and adult cases were 2 years (IQR: 0–5) and 52.5 years (IQR: 35–62), respectively. There were 27 and 45 males in the pediatric and adult groups, and no significant gender difference in the different age groups (p = 0.584) was found. Of 75 cases with underlying diseases, pneumonia (11%), malignancy (11%), hypertension (9.4%), and hepatic cirrhosis (7.9%) were the most common. The incidence of underlying diseases was even higher in the adult group (67.1%) than in the pediatric group (47.1%) (p = 0.028). The frequency of fever, cough, and seizures was significantly higher in the pediatric group than in the adult group, with p -values of 0.004, 0.004, and 0.001, respectively. The percentage of neutrophils in the blood was significantly higher in the adult cases than in the pediatric cases (p < 0.001). Furthermore, there was a significantly higher WBC count (p < 0.001), percentage of neutrophils (p = 0.012), and protein level (p = 0.019) in the CSF samples in the adult patients compared to pediatric patients. The susceptibility rates of S. pneumoniae isolates to vancomycin, linezolid, and levofloxacin were 100%. The susceptibility rates of penicillin were 98.7% and 34.1% in bacteremia and meningitis patients, respectively. Most isolates were resistant to erythromycin, clindamycin, tetracycline, and azithromycin. The most common antibiotic treatment was β-lactams. Seven (5.5%) patients died during hospitalization, and 38 (29.9%) patients' health deteriorated. Conclusion. These results may provide a reference basis for the diagnosis and empiric treatment of IPD in the region. [ABSTRACT FROM AUTHOR]

Black mulberry (Morus nigra L.) is considered a medicinal and food-homologous plant in China. An obstacle to its widespread use is that its annual season and shelf life are extremely short. In this paper, fermented black mulberry juice (FBMJ) was prepared with various probiotic strains, and response surface methodology was used to determine the optimum production conditions for achieving the maximum active substance content in the resulting product. The fermentation process increased levels of biological enzymes and total phenols in the resulting juice. When the ratios of the Lactobacillus inocula to the total inoculum were 27.96% for L. paracasei, 15.37% for L. casei, 16.64% for L. plantarum, and 5.12% for L. delbrueckii, the B. animalis subsp. lactis content reached 15.83%, the L. fermentum content reached 19.08%, and the superoxide dismutase (SOD) activity reached 310 U/g. To study the antioxidant characteristics of the juice, C2C12 cells were treated with H2O2 to induce oxidative stress and the cytoprotective activity of FBMJ was subsequently evaluated. After treatment with FBMJ for 24 h, cell viability was found to be protected under H2O2 exposure, while SOD and glutathione peroxidase (GSH-Px) levels were increased. The reactive oxygen species level and malondialdehyde content were also decreased. These results provide molecular evidence for the antioxidant effect of FBMJ and demonstrate that lactic acid bacteria fermentation has a positive effect on black mulberry juice (BMJ). [ABSTRACT FROM AUTHOR]

Hydrological processes are an important factor influencing the wetland landscapes and the quality of wintering migratory birds habitat in Poyang Lake. However, most of the research on a small spatiotemporal scale and there is a lack of studies on the impact of hydrological processes on migratory bird habitats. This study analysed the response of the Poyang Lake wetland landscape to low water levels from 1990 to 2016 and determined the relationship between hydrological processes, wetland landscape characteristics and migratory bird habitats. According to the results, the number of days during the study period when the maximum water level was higher than the current water level (MaxDay) and the average water level from the 40th to 50th day prior to the current day (D50) are two critical factors affecting the area of grassland in Poyang Lake. In particular, a D50 value of 9.5–11.0 m is important for maintaining the grassland area and growth of wetland vegetation. Besides, the water level should not exceed 11 m from mid–late October to early November and should be maintained between 7.58 and 7.97 m in mid–late December that can maximize the habitat area of migratory birds. Furthermore, this study used ecological threshold to propose the optimal inundation period of Cyperus rotundus L. community, Leersia japonica community, Polygonum criopolitanum community, Phragmites australis community, Triarrhena lutarioriparia community, Carex spp. community and Phalaris arundinacea community, which are 124–174, 31–101, 199–249, 65–147, 51–121, 110–190 and 175–253 days, respectively. [ABSTRACT FROM AUTHOR]

Polychlorinated dibenzo‐p‐dioxins and dibenzofurans (PCDD/Fs) in various foods continuously concern the public. Pork and its byproducts, especially from Yorkshire pigs, are the largest meat food consumed by the general population in China. This study aims to investigate the distribution of PCDD/Fs in different tissues of Yorkshire pigs to understand their bioaccumulation. Yorkshire pigs were fed a known amount of PCDD/Fs through fly ash. PCDD/Fs were determined by isotope dilution method with a gas chromatography‐high resolution mass spectrometer. The liver had the highest concentration levels (2041.33 pg/g lipid) and toxic equivalents values (69.14 pg/g lipid), followed by the spleen and lung, and the lowest ones in the brain. The liver also had the highest bioaccumulation of PCDD/Fs, and this level was considerably higher than that of other tissues. This study showed a strong accumulation capacity of the liver for polychlorinated dibenzo‐p‐dioxins and dibenzofurans under short‐term exposure conditions, suggesting that the liver is a more sensitive tissue for monitoring PCDD/Fs in food safety risk monitoring. Practical Application: This paper may help the consumer in making food choices to minimize the exposure risk to Polychlorinated dibenzo‐p‐dioxins and dibenzofurans. [ABSTRACT FROM AUTHOR]

This study proposes and tests two hypotheses concerning the effects of hotel industry operations on air quality based on data of 26 major tourist cities in China from 2002 to 2017. The empirical analyses take two steps. In the first step, panel regression test results reveal that hotel industry operations (measured by hotel sales revenue) significantly raise the value of particulate matter (PM)2.5 (the key indicator of air quality), supporting the first hypothesis that hotel industry operations deteriorate air quality and providing empirical evidence of the adverse impact of the hotel industry on air quality. In the second step, subsample analyses support the second hypothesis that the impact of hotel sales revenue on air quality diminishes over time. The results from the rolling regression tests validate the existence of a diminishing effect of hotel industry operations on air quality. [ABSTRACT FROM AUTHOR]

With the development of social economy and human activities, the geomorphology and hydrodynamic conditions of coasts have been dramatically changed, causing serious environmental pollution and resource depletion. Taking Quanzhou Bay as an example, this study combined geomorphologic change with a hydrodynamic model to simulate the change in tidal currents in different periods. The results show a change in the coastline was the main cause of hydrodynamic change during the industrialization reform. During the past 70 years, the tidal prism decreased year by year, and the average velocity of the tidal current in the channel decreased by 33.7% and 30.8% at flood and ebb tide, respectively. In the early stages of industrialization, reclamation land was used in a single way. The tidal prism decreased by 22.2% and 29.8% in the spring and neap tide, respectively. In the middle and later stages, the tidal current velocity increased, and reclamation land was used in a variety of ways. In modern society, the reclamation land-use type was unitary. Based on this research, we show the influence of human activities on the evolution of the bay's geomorphology and provide suggestions for the management of the bay. [ABSTRACT FROM AUTHOR]

Objective To investigate the influencing factors of postoperative meningioma recurrence. Methods A total of 176 patients with meningioma treated in Beijing Tiantan Hospital, Capital Medical University from May 2010 to January 2011 were included. The general information, imaging findings, extent of tumor resection and postoperative pathological results were analyzed. Kaplan - Meier survival curve comparison and Log - rank test were used to compare the related influencing factors of meningioma recurrence. Multifactor Cox's proportional hazards regression model was used for survival analysis. Results The median progression free survival (PFS) of patients with preoperative Karnofsky Performance Status (KPS) < 70 was lower than that with KPS ^ 70 [(8.04 ± 1.98) years vs. (8.08 ± 1.18) years; X2 = 5.370, P = 0.020]. The median PFS of patients with peritumoral edema grade 2-3 was lower than that with peritumoral edema grade 0-1 [(8.05 ± 1.79) years vs. (8.06 ± 1.09) years; x = 9.805, P = 0.002]. The median PFS of patients with dural mater invasion was lower than that without dural mater invasion [(7.97 ± 1.70) years vs. (8.06 ± 1.09) years; x = 12.357, P = 0.000]. The median PFS of patients with WHO grade 23 was lower than that with WHO grade 1 [(5.14 ± 2.07) years vs. (8.12 ± 0.87) years; x = 113.774, P = 0.000]. Multivariate Cox's proportional hazards regression model showed that WHO grade 2-3 could increase the risk of postoperative meningioma recurrence (RR = 15.693, 95%CI: 5.905-41.707; P = 0.000). Conclusions The preoperative KPS score, peritumoral edema, dura mater invasion and WHO grade may affect the recurrence of meningioma, and WHO grade 2-3 can increase the risk of meningioma recurrence. [ABSTRACT FROM AUTHOR]

The increased sensitivity of pigs to ambient temperature is due to today's intensive farming. Frequent climate disasters increase the pressure on healthy pig farming. Min pigs are an indigenous pig breed in China with desirable cold resistance characteristics, and hence are ideal for obtaining cold-resistant pig breeds. Therefore, it is important to discover the molecular mechanisms that are activated in response to cold stress in the Min pig. Here, we conducted a transcriptomic analysis of the skeletal muscle of Min pigs under chronic low-temperature acclimation (group A) and acute short cold stress (group B). Cold exposure caused more genes to be upregulated. Totals of 125 and 96 differentially expressed genes (DEGs) were generated from groups A and B. Sixteen common upregulated DEGs were screened; these were concentrated in oxidative stress (SRXN1, MAFF), immune and inflammatory responses (ITPKC, AREG, MMP25, FOSL1), the nervous system (RETREG1, GADD45A, RCAN1), lipid metabolism (LRP11, LIPG, ITGA5, AMPD2), solute transport (SLC19A2, SLC28A1, SLCO4A1), and fertility (HBEGF). There were 102 and 73 genes that were specifically differentially expressed in groups A and B, respectively. The altered mRNAs were enriched in immune, endocrine, and cancer pathways. There were 186 and 91 differentially expressed lncRNAs generated from groups A and B. Analysis of the target genes suggested that they may be involved in regulating the MAPK signaling pathway for resistance to cold. The results of this study provide a comprehensive overview of cold exposure–induced transcriptional patterns in skeletal muscle of the Min pig. These results can guide future molecular studies of cold stress response in pigs for improving cold tolerance as a goal in breeding programs. [ABSTRACT FROM AUTHOR]

IP geolocation is an important basis of location-based network services, while error estimation is an important basis for judging the reliability of results. Most of the existing IP geolocation algorithms cannot estimate the geolocation error. A few can achieve error estimation through high-precision delay measurement, but their performance is also affected by the common delay inflation in the actual network. A new IP target location estimation method is proposed in this manuscript to achieve geolocation with reliable error estimation of IP targets in actual network. Firstly, after the landmark set divided into training set and verification set for path detection, the metropolitan area network (MAN) topology is extracted through train path set. Secondly, the governed landmarks are searched level by level through the MAN, and the minimum covering circles are calculated through the geographical distribution of the landmarks to infer the routers' area center. Then, geolocation errors are counted after simulated geolocation through the verification path set, and the minimum mean square error radius of the error mean and the minimum covering circle radius is calculated as the router area radius. Finally, the path to the IP target is measured and compared with the MAN to get the location estimation result. The experimental results based on 12 cities in China show that compared with the existing typical algorithms, the proposed method not only improves the error estimation accuracy, but also has finer geolocation granularity and lower median error. [ABSTRACT FROM AUTHOR]

Understanding the impact of landscape patterns on ecosystem services (ES) is crucial for the design and management of ecological restoration programs. However, the impacts of landscape configuration on ES from a geospatial perspective have not been studied sufficiently. This study analyzed the landscape composition and pattern changes and quantified the changes in water yield, carbon storage, soil retention, water purification, and habitat quality under the Grain for Green Program (GFGP) from 2000 to 2020 in Kaihua County. The responses of ES to landscape patterns were revealed by geographic detector and geographically weighted regression models. The results showed that landscape fragmentation and diversity increased, and forest landscape area and aggregation increased because of the GFGP implementation. Water yield declined with the decrease in the mean patch area of the landscape, while other ES improved due to the increase in Shannon's diversity index and largest patch index. The interspersion and juxtaposition of cropland and forest land played an important role in improving ES under the GFGP. In addition, some ES may be closely related to natural factors and connection to landscape patterns, such as soil retention and topography, water yield and precipitation, but this response to landscape pattern changes was captured due to the subjective nature of the GFGP. The results can provide scientific guidance for forest landscape restoration to better improve ES. [ABSTRACT FROM AUTHOR]