Search

Previous studies on students' conceptions of learning science (COLS) have focused primarily on formal environments. In these studies, students' COLS were positively associated with their approaches to and outcomes for science learning. However, little research has been conducted to explore students' conceptions of learning science in informal environments (COLSIE), despite its importance to students' academic achievement. To fill this research gap, this study qualitatively and quantitatively explored Chinese primary school students' COLSIE. First, in Study I, interview data gathered from a group of 80 students were analysed using the phenomenographic method, and ten hierarchical categories of COLSIE emerged (e.g., communicating and explaining). Based on these categories, a survey was developed and distributed to another group of 414 students in Study II. Exploratory factor analysis was conducted to validate the survey, which revealed nine factors matching the ten categories except for the initial categories of applying and understanding. This study also revealed the commonalities and uniqueness of COLSIE in comparison with students' COLS in formal environments. The findings suggested that informal science learning experiences may strengthen students' impressions of science practices. Science educators are encouraged to provide their students with opportunities to engage with science practices in informal environments.

SCARECROW-LIKE6 (SCL6) plays a role in the formation and maintenance of the meristem. In Larix kaempferi (Lamb.) Carr., an important afforestation tree species in China, SCL6 (LaSCL6) has two alternative splicing variants—LaSCL6-var1 and LaSCL6-var2—which are regulated by microRNA171. However, their roles are still unclear. In this study, LaSCL6-var1 and LaSCL6-var2 were transformed into the Arabidopsis thaliana (L.) Heynh. genome, and the phenotypic characteristics of transgenic A. thaliana, including the germination percentage, root length, bolting time, flower and silique formation times, inflorescence axis length, and branch and silique numbers, were analyzed to reveal their functions. It was found that LaSCL6-var1 and LaSCL6-var2 overexpression shortened the root length by 41% and 31%, respectively, and increased the inflorescence axis length. Compared with the wild type, the bolting time in transgenic plants was delayed by approximately 2–3 days, the first flower and silique formation times were delayed by approximately 3–4 days, and the last flower and silique formation times were delayed by about 5 days. Overall, the life cycle in transgenic plants was prolonged by approximately 5 days. These results show that LaSCL6 overexpression inhibited the transitions from the vegetative meristem to inflorescence meristem and from the flower meristem to meristem arrest in A. thaliana, revealing the roles of LaSCL6-var1 and LaSCL6-var2 in the fate transition and maintenance of the meristem. [ABSTRACT FROM AUTHOR]

The genus Favolaschia within the family Mycenaceae is characterised by the gelatinous basidiomata with poroid hymenophore and most species inhabit monocotyledonous plants. In this study, many samples covering a wide geographic range in China were examined morphologically and phylogenetically using concatenated ITS1-5.8S-ITS2-nLSU sequence data. Three new species clustering in Favolaschia sect. Anechinus, namely Favolaschia imbricata, F. miscanthi and F. sinarundinariae, are described. Favolaschia imbricata is characterised by imbricate basidiomata with pale grey to greyish colour when fresh and broadly ellipsoid basidiospores measuring 7–9 × 5–6.8 µm; F. miscanthi is characterised by satin white basidiomata when fresh, broadly ellipsoid basidiospores measuring 7.5–10 × 5.5–7 µm and inhabit rotten Miscanthus; F. sinarundinariae is characterised by greyish-white basidiomata when fresh, dark grey near the base upon drying, broadly ellipsoid to subglobose basidiospores measuring 7–9 × 5–7 µm and inhabit dead Sinarundinaria. The differences amongst the new species and their morphologically similar and phylogenetically related species are discussed. In addition, an updated key to 19 species of Favolaschia found in China is provided. [ABSTRACT FROM AUTHOR]

Objectives: Pharyngocutaneous fistula (PCF) formation following open surgical treatment of hypopharyngeal cancer (HPC) is a common and troublesome complication. To date, the postoperative protocol of restarting oral intake is not clear, and vast discrepancies exist in the literature and among institutions. This study aimed to explore the impact of a postoperative protocol of restarting oral intake on PCF formation after open surgical treatment of primary HPC, and its impact on overall survival (OS) and swallowing function based on the functional outcome swallowing scale (FOSS). Materials and Methods: This was a prospective observational study of 42 patients who received open surgical treatment for primary HPC at Beijing Friendship Hospital between April 2019 and August 2021. This cohort included two groups: patients who restarted oral intake on the 10th postoperative day (Group 1), and those who started on the 20th (Group 2). The Chi-square test and Fisher's exact chi-squared test were used for comparing qualitative data among the groups. Results: Group 1 (n = 27) and Group 2 (n = 15) were comparable in clinical characteristics. PCF occurred in 7 (25.9%) patients in Group 1, while none occurred in Group 2 (P = 0.038). The 2-year OS of all 42 patients was 75.6%; 65.8% and 93.3% for Groups 1 and 2, respectively (P = 0.07). The swallowing function was satisfactory (FOSS Grades 0–III) for 19 (70.4%) patients in Group 1 and 15 (100%) patients in Group 2 (P = 0.035). Laryngeal preservation was achieved in 25 (59.5%) patients, while decannulation was successful in 22 (88.0%) patients. Conclusions: Delayed oral feeding significantly reduces PCF after open surgical treatment of primary HPC, and improves the swallowing function outcome without jeopardizing the OS. [ABSTRACT FROM AUTHOR]

Background and Objectives: The present study aims to evaluate the iron stores in plasmapheresis donors and develop and validate an iron deficiency (ID) risk prediction model for plasmapheresis donors with potential or existing ID. Materials and Methods: We assessed plasmapheresis donors' serum ferritin (SF) and haemoglobin (Hb) levels. The candidate factors showing significant differences in the multivariate logistic regression analysis were used to establish a risk prediction scoring system. The participants were divided into a training cohort and an internal validation cohort in a 7:3 ratio. Additional plasmapheresis donors from a different station were recruited for external validation. Results: The SF levels in both male and female donors in the high‐frequency group were significantly lower than those of new donors (male: p < 0.001; female: p = 0.008). The prevalence of ID in female regular donors with a high frequency was significantly higher than that in new donors (33.1% vs. 24.6%; odds ratio = 1.209 [95% CI: 1.035–1.412]). Donation frequency, age, Hb, body mass index and being pre‐menopausal were identified as independent risk factors for ID (p < 0.05). The developed model exhibited good discrimination ability (area under the receiver operating characteristic curve >0.7) and calibration (p > 0.05) in development, internal validation cohorts and external validation cohorts. Conclusion: A higher donation frequency has been associated with reduced SF levels and an increased risk of ID in women. The developed ID risk prediction model demonstrates moderate discriminative power and good model fitting, suggesting its potential clinical utility. [ABSTRACT FROM AUTHOR]

The article discusses the impact of WeChat on children's data privacy and China's legal framework for safeguarding online safety. It highlights the conflicts between commercial interests and children's wellbeing, as well as the issues with behavior tracking and age verification. It mentions that, despite China's robust legal framework, and it emphasizes the need for more effective safeguards due to WeChat's data aggregation.

Background: Larynx preservation surgery (LPS) combined with multimodal adjuvant therapy (MAT) is re-emerging as treatment option for hypopharyngeal cancer (HPC). This study aims to explore the survival and functional outcome of this combined approach. Methods: This is a retrospective cohort study. Selected patients with primary HPC treated by LPS and MAT at two large Beijing medical centers between 2005 and 2019 were included. In addition to LPS, patients received one or more of the following treatments: preoperative induction chemotherapy, postoperative intensity-modulated radiotherapy, chemotherapy, or targeted therapy. Results: In total, 64 patients were included (62 were men, and median age was 57.5 years). The disease in most patients was in stage III (28.1%) or IV (56.3%), or in stage T2 (34.4%) or T3 (45.3%), based on the TNM scale. Across all patients, the rate of overall survival (OS) was 60.7% at 3 yr and 47.3% at 5 yr. OS was significantly higher for patients with stage I or II disease than for those with stage III or IV disease (HR 8.64, 95% CI 3.69–20.2, log-rank P =.010). Decannulation was successful in 55 patients (85.9%), and swallowing function was satisfactory (stage 0–III, on Functional Outcome Swallowing Scale) for 50 (78.1%). Median Voice Handicap Index-10 score on voice performance was 19 (range 4–40), and median Functional Assessment of Cancer Therapy-General Questionnaire score for QoL was 75 (range 16–105). Conclusions: LPS and MAT can provide satisfactory oncologic control and good functional outcomes for selected patients with HPC, especially those with stage I or II disease. [ABSTRACT FROM AUTHOR]

Background: Among six extant tiger subspecies, the South China tiger (Panthera tigris amoyensis) once was widely distributed but is now the rarest one and extinct in the wild. All living South China tigers are descendants of only two male and four female wild-caught tigers and they survive solely in zoos after 60 years of effective conservation efforts. Inbreeding depression and hybridization with other tiger subspecies were believed to have occurred within the small, captive South China tiger population. It is therefore urgently needed to examine the genomic landscape of existing genetic variation among the South China tigers. Results: In this study, we assembled a high-quality chromosome-level genome using long-read sequences and re-sequenced 29 high-depth genomes of the South China tigers. By combining and comparing our data with the other 40 genomes of six tiger subspecies, we identified two significantly differentiated genomic lineages among the South China tigers, which harbored some rare genetic variants introgressed from other tiger subspecies and thus maintained a moderate genetic diversity. We noticed that the South China tiger had higher FROH values for longer runs of homozygosity (ROH > 1 Mb), an indication of recent inbreeding/founder events. We also observed that the South China tiger had the least frequent homozygous genotypes of both high- and moderate-impact deleterious mutations, and lower mutation loads than both Amur and Sumatran tigers. Altogether, our analyses indicated an effective genetic purging of deleterious mutations in homozygous states from the South China tiger, following its population contraction with a controlled increase in inbreeding based on its pedigree records. Conclusions: The identification of two unique founder/genomic lineages coupled with active genetic purging of deleterious mutations in homozygous states and the genomic resources generated in our study pave the way for a genomics-informed conservation, following the real-time monitoring and rational exchange of reproductive South China tigers among zoos. [ABSTRACT FROM AUTHOR]

Background: Currently, there is no generally approved surgical treatment for patients with primary angle-closure glaucoma (PACG) and co-existing cataracts. The aim of this systematic review and meta-analysis was to compare the efficacy and safety of phacoemulsification and phacotrabeculectomy in PACG patients with cataract. Methods: Diverse databases were searched, including PubMed, MEDLINE, EMBASE, Cochrane Library, Chinese Journal Full-text Database (CNKI), Wanfang database, and China Science and Technology Journal Database, for randomized controlled trials (RCTs) on phacoemulsification and phacotrabeculectomy for the treatment of PACG published up to 30 June 2021. ReviewManager (RevMan) version 5.4 software was used for the meta-analysis, and the effective quantity of measurement data was measured by the mean difference (MD) and 95% confidence interval (CI). The effect of counting data was measured by odds ratio (OR). Results: Our search of the databases identified 14 RCTs that satisfied the search criteria. Meta-analysis of these 14 RCTs showed that at the 1 month postoperative follow-up, intraocular pressure (IOP) of patients in the phacoemulsification group was higher than that of patients in the phacotrabeculectomy group (MD 2.04, 95% CI 1.42–2.65; P < 0.00001). However, the postoperative IOP was not significantly different between the two groups at the 3, 6, and 12 months postoperative follow-ups (P = 0.52, P = 0.51, and P = 0.05, respectively). More medications for IOP reduction were required by patients in the phacoemulsification group compared with those in the phacotrabeculectomy group at 3 months postoperation (MD 0.76, 95% CI 0.33–1.18; P = 0.0005), 6 months postoperation (MD 0.66, 95% CI 0.15–1.18; P = 0.01), and 12 months postoperation (MD 0.76, 95% CI 0.22–1.30; P = 0.006). Patients in the phacoemulsification group obtained better best corrected visual acuity (BCVA) than those in the phacotrabeculectomy group (MD − 0.17, 95% CI − 0.34 to − 0.01; P = 0.04) at 3 months postoperation, but there was no significant difference in BCVA between the two groups at 6 and 12 months postoperation (P = 0.33 and P = 0.56, respectively). The deepened anterior chamber was more obvious in patients in the phacoemulsification group versus those in the phacotrabeculectomy group (MD 0.61, 95% CI 0.03–1.18; P = 0.04). Patients in the phacoemulsification group experienced fewer postoperative complications than those in the phacotrabeculectomy group (OR 0.27, 95% CI 0.17–0.42; P < 0.00001). Conclusion: Our results provide evidence that phacotrabeculectomy has advantages over phacoemulsification for the treatment of PACG in terms of better IOP and reduced medication need during the early stage post surgery. However, in terms of the complication risk, phacoemulsification is the more secure treatment option. [ABSTRACT FROM AUTHOR]

Background: Few studies have focused on the work engagement of infection control nurses (ICNs). The perceived organizational support (POS) and psychological capital (PsyCap) might be important factors influencing ICNs' work engagement. Moreover, PsyCap might play a mediating role in the relationship between POS and work engagement. Objective: This study aims to clarify the relationships among POS, PsyCap and work engagement of Chinese ICNs. Methods: A cross-sectional design was performed to collect data on 7382 ICNs from 20 provinces in China. Data collection was conducted by an online questionnaire, including questions about demographics, the Chinese version of the Utrecht work engagement scale (UWES), the Chinese version of the psychological capital questionnaire (PCQ) and the perceived organizational support scale for medical staff. Univariate analysis, the Spearman correlation method and the mediating effect test were conducted. Results: The work engagement was at a relatively high level, with a total score of 80.87 ± 14.95. The total scores of POS and PsyCap scale were 41.45 ± 7.37 and 89.14 ± 9.06 respectively, both of which were at the upper-middle level. Work engagement was positively associated with both POS and PsyCap (both P< 0.01). Furthermore, the mediating effect of PsyCap on the relationship between POS and work engagement was 0.394, the total effect was 0.443, and the ratio of mediating effect to total effect was 88.94%. Conclusion: The findings suggest that both POS and PsyCap can directly increase the work engagement of the Chinese ICNs. Besides, POS can indirectly improve work engagement, partially through PsyCap. Therefore, enhancing POS and PsyCap could be effective in improving the work engagement of ICNs. [ABSTRACT FROM AUTHOR]

As the net effect of agglomeration on entrepreneurship depends on the trade-off between positive and negative effects, urban agglomeration can either promote or discourage entrepreneurial activity in theory. However, there is an unexpected shortage of empirical confirmations on this potential cause-and-effect relationship. Our study strives to fill this empirical gap by providing credible evidence whether agglomeration, measured by the urban density or population, increases the probability of individuals being self-employed. Based on the China Labor-Force Dynamic Survey of 2012, 2014, and 2016, we find that big cities fail to facilitate individuals to start or run their own businesses. Further analyses illustrate that the entrepreneurs in large cities can be easily tempted by a wider range of salaried opportunities and are generally exposed to high fixed costs and intense competition. In contrast, entrepreneurship in large cities is of high reward. These results serve as direct evidence of the co-existence of agglomeration diseconomies and economies. This also suggests the direction of government policy in large cities, which is to alleviate, as much as possible, the negative impact on entrepreneurs. [ABSTRACT FROM AUTHOR]

Chuanxiong (CX, Ligusticum chuanxiong), Japanese Chuanxiong (JCX, Cnidium officinale), Fuxiong (FX, Ligusticum sinense 'Fuxiong'), and Jinxiong (JX, Ligusticum sinense 'Jinxiong') are aromatic herbs used in China, Japan, and other regions. Their morphology and aromatic odor are similar, resulting in confused and mixed uses. This study compares the volatile compositions of these herbs for defining their medical uses. Headspace solid-phase microextraction–gas chromatography–triple quadrupole–mass spectrometry was employed to separate, identify, and quantify the compounds in the volatile gas of the four herbs. A total of 128 volatile compounds were identified and quantified in 23 these herbal samples. The sums of 106, 115, 116, and 120 compounds were detected in the volatile gas of CX, JCX, FX, and JX, with the mean contents of 4.80, 7.12, 7.67, and 12.0 μg/g, respectively. Types and contents of the main compounds were found to be different in the volatile gas of these herbs. The orthogonal partial least squares discriminant analysis and hierarchical clustering analysis showed the four herbs located in different confined areas or clusters. It is concluded that the volatile compositions in the four herbs are generally similar, but the contents of main volatile compounds are different. These herbs should be clearly differentiated in medical use. [ABSTRACT FROM AUTHOR]

To address the problem that the accuracy of the SVM algorithm is affected by random parameters at the input end, a financial crisis early warning model (FCEWM) based on PSO-SVM is constructed based on the nonequilibrium sample characteristics of different financial conditions of listed companies in China's gem. The model uses the PSO algorithm to optimize the parameters of SVM and selects 24 financial risk evaluation indexes as the input to predict the financial crisis. The results show that the proposed model is superior to other models in prediction accuracy and robustness. [ABSTRACT FROM AUTHOR]

Purpose: Short-term spinal cord stimulation (st-SCS) has been widely used to treat herpetic-related neuralgia (HN) in China for several years, but is still heavily debated as it has no strong evidence in clinical application. Therefore, a questionnaire survey among the Chinese pain specialist workgroup of the Chinese Neuromodulation Society and Chinese Medical Doctor Association was carried out to achieve a consensus about the clinical use of st-SCS for HN treatment. Methods: The contents of the questionnaire include basic information about doctors (hospital level, work experience, training, procedure numbers, etc.), efficacy, indications, and contraindications of st-SCS, operation conditions, and preoperative preparation of st-SCS, and the prospect of the st-SCS procedure. Initially, the survey was conducted on 110 experts who have practiced the st-SCS procedure from all over the provinces in China. Finally, valuable data was calculated from the 110 questionnaires excluding the doctors with <1 year of experience of st-SCS, <10 cases of procedures per year, and no standard training in SCS technique. Results: Based on the 110 questionnaires, it is estimated that 5,000 to 10,000 cases of electrical stimulation are carried out nationwide each year. Sixty- nine valid questionnaires acquired from senior pain physicians were more valuable and specialized in the efficacy, indications, and contraindications of st-SCS for HN. It was commonly agreed (97.10%) that the HN patients with <3 months will obtain good effectiveness (patient satisfaction rate ≥50%). Almost all (98.55%) agreed that st-SCS can be used in SHN patients, there was a common agreement (72.46%) that AHN patients are an indication of st-SCS, and more than half agreement (53.62%) that st-SCS may be fit for early PHN (3--6 months). A common agreement (79.71%) was achieved that more than half of HN patients had the experience of nerve block or nerve pulsed RF. A similarly large number of experts 57/69 (82.61%) agreed that an 80%paresthesia coverage should be achieved at the test stimulation and 57/69 (82.61%) agreed that the treatment of st-SCS need be persistent for 1--2 weeks. Conclusions: Early HN patients can get an effective outcome from the treatment of st-SCS and maybe the indication of st-SCS. Moreover, standardized training for pain physicians and basic research and clinical studies are warranted. [ABSTRACT FROM AUTHOR]

Objective: Under current standards of treating highly aggressive hypopharyngeal cancer (HPC), oncological control and functional outcome are still unsatisfactory worldwide. This study explored the surgery-oriented comprehensive treatment approach based on 15 years of practice. Methods: A retrospective cohort of HPC patients treated by the senior author at Chinese PLA General Hospital between Nov 2005 and Aug 2012 and Capital Medical University Beijing Friendship Hospital between May 2014 and Nov 2019 was studied. Oncological control, swallowing function, and quality of life (QoL) were assessed. Results: In total, 122 patients were included in this study, with 11 (9.0%) cases in the early stage and 111 (91.0%) cases in the advanced stage. Five-year overall survival (OS) and disease-free survival (DFS) were 40.0% and 36.1%, respectively. The swallowing outcome was satisfactory in 90 (73.8%) patients. Tracheostomy-free survival was achieved in 55 (45.1%) patients. Multivariate cox regression analysis showed that the size of the surgical defect, local-regional recurrence, and distant metastasis were independent impact factors for OS and DFS (P <.05). Multivariate analysis showed that the logistic regression coefficients (standard error) of pharyngo-cutaneous fistula and local-regional recurrence on swallowing function were 1.274 (.532) and 1.283 (.496), respectively (P <.05). In addition, the logistic regression coefficients (standard error) of the clinical stage, local-regional recurrence, decannulation, and feeding tube on QoL were −7.803 (3.593), −7.699 (3.151), 13.853 (3.494), and −20.243 (3.696), respectively (P <.05). Conclusions: Surgery-oriented comprehensive treatment can give rise to good swallowing function without jeopardizing oncological control. The size of the surgical defect, local-regional recurrence, and distant metastasis were independent factors impacting OS and DFS. Pharyngo-cutaneous fistula and local-regional recurrence were independent factors impacting swallowing function. Clinical stage, local-regional recurrence, decannulation, and feeding tube were independent factors impacting QoL. [ABSTRACT FROM AUTHOR]

Polycentric planning strategies have often failed to achieve the expected effects. The ensuing uncertainty associated with the desirability of polycentric strategies is also reflected in the early literature which offers no clear conclusion about whether the polycentricity affects economic performance and how. This paper aims at offering a clear conclusion about it, especially its dependence on city size. Against this backdrop, we conceptualize polycentricity as a process of reclustering after decentralization to reevaluate its impact on performance. To this end, we use the city proper level Chinese Economic Census (2004, 2008, and 2013) and apply a fixed-effects panel model, the results of which show that the dependence of the urban economy on spatial structure is contingent on city size. More specifically, both decentralization and clustering (and therefore the polycentric structure) facilitate economic performance only when cities reach a certain size. We use our findings as the basis for outlining an emergent research agenda for urban polycentricity. [ABSTRACT FROM AUTHOR]

With the rapid development of high-speed rail in China, addressing the issue of safety assurance during the operation of the train is very important. A very important part of a train's power supply system is the pantograph and catenary system, which consists of a pantograph and a catenary. Failure of the pantograph-catenary system can cause significant damage to the normal operation of the train. The dynamic performance of the pantograph-catheter system must be detected in real time during the operation of the train. This paper is based on the study and analysis of pantograph-catheter dynamic performance parameters and developed a system for real-time detection of pantograph-catheter dynamic performance parameters based on a car visual system. The results are as follows: based on this detection method, the visual error is low and the accuracy is high. The machine-based directional height detection module developed in this paper has a good detection effect and high test accuracy; the arcing detection module designed in this paper can effectively detect the arcing and store the arcing pictures and can display the duration of single arcing and the arcing rate of the section in real-time. The practical application effect is good. The results show that the focal length of the camera lens is 16 mm, and the error of the machine vision system is low. The system designed in this paper may make a great contribution to the operation condition monitoring and fault diagnosis of the pantograph-catenary system of a high-speed train in the future. [ABSTRACT FROM AUTHOR]

Copyright of Papers in Regional Science is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Debris slopes are widely distributed across the Three Gorges Reservoir area in China, and seasonal fluctuations of the water level in the area tend to cause high-frequency microseisms that subsequently induce landslides on such debris slopes. In this study, a cumulative damage model of debris slope with varying slope characteristics under the effects of frequent microseisms was established, based on the accurate definition of slope damage variables. The cumulative damage behaviour and the mechanisms of slope instability and sliding under frequent microseisms were thus systematically investigated through a series of shaking table tests and discrete element numerical simulations, and the influences of related parameters such as bedrock, dry density and stone content were discussed. The results showed that the instability mode of a debris slope can be divided into a vibration-compaction stage, a crack generation stage, a crack development stage, and an instability stage. Under the action of frequent microseisms, debris slope undergoes the last three stages cyclically, which causes the accumulation to slide out in layers under the synergistic action of tension and shear, causing the slope to become destabilised. There are two sliding surfaces as well as the parallel tensile surfaces in the final instability of the debris slope. In the process of instability, the development trend of the damage accumulation curve remains similar for debris slopes with different parameters. However, the initial vibration compaction effect in the bedrock-free model is stronger than that in the bedrock model, with the overall cumulative damage degree in the former being lower than that of the latter. The damage degree of the debris slope with high dry density also develops more slowly than that of the debris slope with low dry density. The damage development rate of the debris slope does not always decrease with the increase of stone content. The damage degree growth rate of the debris slope with the optimal stone content is the lowest, and the increase or decrease of the stone content makes the debris slope instability happen earlier. The numerical simulation study also further reveals that the damage in the debris slope mainly develops in the form of crack formation and penetration, in which, shear failure occurs more frequently in the debris slope. [ABSTRACT FROM AUTHOR]

As one of the most seriously arid areas in China, the Qaidam Basin (QB) features a notable growing probability of intense rainfall under global warming. Compared to a normal/humid region, intense rainfall usually results in more severe disasters in an arid area. Considering that few studies focused on intense rainfall within the QB, there is an urgent need to understand the mechanisms governing intense rainfall in this region. A type of Tibetan Plateau vortex (TPV) associated intense rainfall within the QB was investigated in this study, which partly fills the existing research gaps in the field. The main findings are as follows: (a) the intense‐rainfall‐producing TPV formed and maintained in a favorable background environment which was characterized by a notable upper‐level divergence north of a strong upper‐level jet and a strong middle‐level warm advection ahead of a shortwave trough over the Tibetan Plateau. (b) Vorticity budget indicates that two factors affected the vortex's formation notably, one was the convergence‐related vertical stretching, which dominated the vortex's formation and the other was the import of the horizontal transport of anticyclonic vorticity which was the most detrimental factor for the formation of the TPV. Tilting and vertical transport only exerted weak effects on the TPV's formation, since convective activities were relatively weak in this event. (c) Moisture budget shows that the southwestern and southern moisture transport channels, which were mainly driven by the wind field associated with the shortwave trough over the Tibetan Plateau, contributed ~70% to the total moisture income of the intense rainfall within the QB. The transport was accomplished primarily through the southern boundary of the QB, with the moisture mainly coming from the Indian Peninsula and Indochina Peninsula. [ABSTRACT FROM AUTHOR]

Archean magmatic Ni‐Cu‐[platinum‐group element (PGE)] deposits are very important and mainly associated with komatiitic rocks in intracratonic rift zones throughout the world. However, the Taoke Ni‐Cu‐(PGE) deposit in the North China Craton, which is the oldest (Neoarchean, 2,537 Ma) magmatic sulphide deposit in China, and is genetically related to the subduction zone. The intrusion is predominantly composed of a small ultramafic body (olivine websterite) and a much larger gabbroic body (gabbronorite). Sulphide mineralization is mainly associated with the ultramafic body with average grades of 0.66 wt% Ni, 0.62 wt% Cu and ~1 g/t PGE. Sulphides of the Taoke deposit are characterized by a chalcopyrite + pentlandite + pyrrhotite + millerite assemblage, which hosts variable amounts of platinum‐group minerals. Good correlations are found for Pd versus individual Ir subgroup of platinum‐group elements (IPGEs; i.e., Pd vs. Os, Ir, Ru, and Rh) and for Ir and Pd subgroup of platinum‐group elements (PPGEs; i.e., Ir vs. Pt and Pd), indicating that the PGE contents of immiscible sulphide liquids in the Taoke deposit are mainly controlled by the initial PGE concentrations in the parental magma and R factor (magma/sulphide mass ratio). Based on our calculations, the initial contents of Ir and Pd in the parental magma are estimated to be 0.13 and 5.6 ppb, respectively, suggesting that the parental magma of the Taoke deposit is PGE undepleted. The multiple sulphur isotopes can provide direct indications of the source of sulphur for the Archean intrusion. The γOs(t) values and Archean crustal sulphur (three samples have anomalous Δ33S values <−0.1‰) suggest that the addition of crustal sulphur occurred in the magma. Fractional crystallization and the addition of crustal sulphur are the most likely key factors for sulphide saturation in the Taoke mafic magma. [ABSTRACT FROM AUTHOR]

Aims: To investigate the attitudes and beliefs towards the implementation of nurse prescribing among general nurses and nurse specialists. Design: A cross‐sectional survey among general nurses and nurse specialists was conducted in seven provinces and one autonomous region in mainland China using convenience sampling method. Methods: The attitudes and beliefs towards nurse prescribing were assessed using the Nurse Attitudes and Beliefs towards Nurse prescribing scale, of which Cronbach's coefficient was 0.902, retest reliability was 0.808. Respondents from eight hospitals across the country were employed to complete an online questionnaire. Results: Nurse specialists (n = 399) had statistically significantly more favourable intentions towards nurse prescribing than general nurses (n = 415; 105.64 ± 12.83 vs. 96.39 ± 13.16; p <.001). The years of clinical work experience, professional title, education degree were positively correlated with general nurses' and nurse specialists' attitudes and beliefs towards nurse prescribing (p <.05). Among nurse specialists, the variety of specialties and whether they work in nurse‐led clinics on an outpatient basis have positively influence on their intentions towards nurse prescribing (p <.05). [ABSTRACT FROM AUTHOR]

The taxonomy of woody bamboo presents many difficulties due to its long blooming interval and complex morphological variation. Whether the current taxonomy reflects genuine species divergence within woody bamboo is an intriguing question. The Fargesia spathacea Franch. complex comprises 15 closely related species with a sympatric distribution in China. Their classification has long been controversial because only a handful of vegetative traits are available, providing a good opportunity to explore the evolutionary relationships and genetic differentiation in woody bamboo. Here, we present a study involving 750 individuals from 39 representative populations in the F. spathacea complex using 14 simple sequence repeat markers. We found varying degrees of genetic diversity across populations of the F. spathacea complex (He = 0.07–0.81) and largely negative F‐values at the population level, implying an excess of heterozygotes in the populations. Phylogenetic analyses revealed that all populations were divided into two major groups (clusters A and B), with the majority of the 15 species representing distinct genetic lineages. Based on population genetic analysis along with morphological evidence, we confirmed the identity of three species (F. decurvata J. L. Lu, F. spathacea, and F. murielae Gamble) and suggested the invalidation of four other species (F. scabrida T. P. Yi, F. robusta T. P. Yi, F. denudata T. P. Yi F. murielae (Gamble) T. P. Yi, and F. nitida (Mitford) Keng f. ex T. P. Yi). The delimitation of the remaining eight species has yet to be explored. The analysis of ecological factors and spatial autocorrelation suggested that altitudinal differences might account for the distinct genetic divergence between the two major groups. [ABSTRACT FROM AUTHOR]

Glioma is one particular type of brain malignancy which is highly complex and usually has a poor prognosis. Despite the limited diagnostic level of glioma, the survival time of affected patients broadly varies. Here, we conducted a detailed analysis, regarding the differences in patient survival time, to discover potential survival-related genes in glioma as well as their putative regulatory mechanisms. To contextualize the acquisition of these potential prognosis markers in large populations, particularly in China, we combined CGGA and The Cancer Genome Atlas (TCGA) databases to properly identify genes that are significantly related to survival. Our workflow combined a series of analytical approaches, including differential analysis, survival time, co-expression, clinical correlation analysis, ROC curve evaluation and prediction ability. Our results indicate that the four particular genes - PLAT, IGFBP2, BCAT1, SERPINH1 could be used as independent prognostic marker genes. These genes have also shown good prognostic ability in distinct populations, reiterating the robustness and value of these prognostic markers. [ABSTRACT FROM AUTHOR]

The Shuitoushan Pb–Zn deposit, which is located in the southern Baoshan Block of Sanjiang region, SW China, forms an important part of the Luziyuan polymetallic ore field. The origin of ore‐forming fluids and the genesis of this deposit are rarely reported. In this study, we present the results of geological features, fluid‐inclusion and isotopic (O, S, Pb) analyses of the Shuitoushan deposit. The mineralization process of this deposit can be divided into three stages: pyrite‐quartz stage (Stage I), sphalerite‐galena‐chalcopyrite stage (Stage II), and chalcopyrite‐calcite stage (Stage III), with a relatively medium‐low temperature (their homogenization temperatures ranging from 261 to 340°C, 219 to 300°C, and 159 to 225°C, respectively) and low salinity (their salinities varying from 2.1 to 6.8 wt% NaCleqv., 1.2 to 4.9 wt% NaCleqv. and 0.7 to 3.85 wt% NaCleqv., respectively), as revealed by microthermometry study of three types of fluid inclusions, namely L‐type (liquid‐rich), V‐type (vapor‐rich), and PL‐type (pure liquid), distinguished in ore‐bearing quartz veins. The decline of δ18OH2O values (decreasing from 7.58‰ in early stage to 0.08‰ in late stage) of the mineralizing fluid indicates an initial magmatic water source of it, with a gradually increasing input of meteoric water during the process of evolution. The ore‐forming materials are likely to be mainly derived from the concealed intermediate‐acid intrusions and also wall rocks, as suggested by the δ34S values (4.1–12.2‰) and Pb isotope compositions (206Pb/204Pb = 18.325–18.448, 207Pb/204Pb = 15.806–15.944, 208Pb/204Pb = 38.822–39.439) of sulphides in ores. Above all, the Shuitoushan deposit can be classified as an epithermal Pb–Zn deposit. This study also indicates that the Pb–Zn polymetallic deposits in the Luziyuan ore field have similar ore‐forming fluids and materials sources, the distribution and mineralization process of which are controlled by the concealed intermediate‐acid intrusion at depth in Luziyuan, Wumulan, and Shuitoushan areas. [ABSTRACT FROM AUTHOR]

Alstonia scholaris could be used as a traditional medicinal plant in China for the treatment of acute respiratory, which might be caused by respiratory tract infections. The investigation tested the anti-infective effects of total alkaloids extract (TA) from leaves of A. scholaris, and as a result, TA inhibited herpes simplex virus type 1 (HSV-1), respiratory syncytial virus (RSV) and influenza A virus (H1N1) in vitro respectively. In addition, the survival days of mice were prolonged, and the lung weights and mortality of mice were decreased significantly, after oral administrated TA in H1N1 and beta-hemolytic streptococcus infectious models in vivo respectively. The finding supported partly the traditional usage of A. scholaris in the treatment of respiratory infections. [ABSTRACT FROM AUTHOR]

Copyright of Acta Oto-Laryngologica is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Understanding the anisotropic behavior of jointed rock mass subjected to various confining pressures is crucial for designing, evaluating the performance and assessing the stability of rock engineering structures. We report here our numerical investigation of the response of stress-dependent anisotropy of a jointed rock mass sourced from the weakly weathered zone of the water inlet slope of the Xiaowan Hydropower Station, China. The finite element method (FEM) that incorporates material heterogeneity and joint network was utilized. Two-dimensional models were established based on the Monte-Carlo method and loaded in different rotational angles with changing confining pressures at the representative elementary volume (REV) size (14 × 14 m). The stress–strain behaviors, failure patterns, deformation modulus and peak strength of the REV models exhibited noticeable stress dependency and directionality. The cohesive strength was anisotropic, whereas there was only an insignificant change in the friction angle with changes in the rotational angle. The effect of confining pressure on the anisotropy index of the deformation modulus was negligible, while the anisotropy index of peak strength decreased gradually with confining pressure. Based on these results, we conclude that stress conditions need to be considered for accurate prediction of the mechanical behavior of a jointed rock mass. [ABSTRACT FROM AUTHOR]

Scatophagus argus is an important marine culture fish in South and South-East Asia, including Southeast coastal areas of China. Artificial propagation technology for S. argus is not optimum; thus further studies on its reproduction biology are required. Although previous studies have shown that leptin (Lep) can regulate fish reproduction, the role of lep genes in S. argus is unknown. Herein, in silico analysis showed that S. argus has two lep genes (lepa and lepb). Protein 3D-structure prediction showed that Lepa has four α-helices (similar to mammals), while Lepb only has three. Tissue distribution analysis showed that lepa is highly expressed in the liver, whereas lepb was not detected in any tissue. Notably, lepr was expressed in all tissues. Lepa mRNA expression levels in the liver and serum Lep, estradiol (E 2) and vitellogenin (Vtg) levels of female fish were significantly higher in ovaries at stage IV than in ovaries at stage II. Serum E 2 levels were significantly positively correlated with Vtg levels in female fish at different development stages, while serum E 2 was not correlated with Lep levels. Consistently, in vitro incubation of the liver with E 2 significantly up-regulated vtga , while it did not affect lepa expression. Recombinant Lep (10 nM) significantly up-regulated chicken gonadotropin-releasing hormone (cGnRH/GnRH-II) in the hypothalamus and GnRH receptor (GnRHR) and luteinizing hormone beta (Lhb) in the pituitary. These results suggest that lepa regulates female reproduction in S. argus. [Display omitted] • Lepa expression in Scatophagus argus increases during ovary maturation. • Serum leptin level is not correlated with serum estrogen level. • Estrogen in vitro incubation cannot up-regulate liver lepa. • Recombinant leptin up-regulates cGnRH and Lhb in vitro. [ABSTRACT FROM AUTHOR]

Assessing the contribution of sediments from different sources is essential to understand erosive processes and formulate further soil conservation strategies to address environmental problems. In this study, we combined the source fingerprinting approach with geochemistry, including comparison of potential sources, and distribution pattern of major elements, to estimate the different land-use relative contributions to streambed sediment in the Luowugou catchment (13.5 km2) located on the Heishui River, the first branch of the Jinsha River, China. A total of 57 samples from stream bank, cropland, grassland, forest land, and sediments were collected, and then, 15 elements were analyzed for each sample. The fingerprinting results demonstrated that the stream bank (62.4%) had the greatest relative contribution to the bed sediment yield, while cropland, grassland, and forest land contributed 18.6%, 14.9%, and 4.1% to the bed sediments, respectively. In comparison to the fingerprinting method, even though the results upon geochemistry only provide a qualitative assessment, the ranking of sediment contributions based on geochemistry was consistent with the sediment fingerprinting ranking, that is, stream bank>cropland>grassland>forest land. Our findings suggest that the focal point for sediment control practices should be the stream bank rather than cropland in the region. Geochemistry can result in an important means in validating the fingerprinting results. [ABSTRACT FROM AUTHOR]

This paper examines the effect of spatial structure, as measured on the monocentricity–polycentricity dimension, on labour productivity at the prefectural level in China. Using pooled cross-sectional and instrumental variable techniques, we find that, all else being equal, prefectures with a more monocentric spatial structure have a higher labour productivity, robust to different specifications. Furthermore, large agglomeration economies may fuel the beneficial effects of monocentricity. We conclude that, in terms of economic performance, monocentric-oriented spatial strategy could be a better choice for Chinese prefecture-scale regions. [ABSTRACT FROM AUTHOR]

The Brown Parrotbill (Cholornis unicolor) is endemic to the central and eastern Himalayas and occurs in alpine bamboo thickets at an altitude of 1,980–3,600 m. Fieldwork was conducted in the Gaoligongshan National Nature Reserve and cameras were used to record reproductive behaviors. Duration of incubation, nestling provisioning, and other parental care behaviors were extracted from the videos, and measurements of the nest, eggs, and nestlings were taken in the field. One nest with a clutch of 3 eggs was found 2.1 m above the ground in a bamboo thicket in May, thus extending the documented breeding season. Two of the three eggs hatched and both nestlings fledged. Both the male and the female incubated the eggs and brooded and provisioned the nestlings. The incubation period lasted for at least 13 d and the nestling period was 15 d. As incubation progressed, incubation-bout duration decreased and recess frequency increased. During the nestling period, the frequency of parental provisioning increased as the nestlings matured. Our observations provide the first description of the nest, nestlings, and incubation behavior of Brown Parrotbill. Alpine bamboo thickets are assumed to be an important breeding habitat for Brown Parrotbills, as this is typical for at least 6 parrotbill species. [ABSTRACT FROM AUTHOR]

Abstract As an important economical shellfish in coastal area of China, abalone is susceptible to bacterial infection, especially Vibiro parahemolyticus (V. parahemolyticus). Matrix metalloproteinases (MMPs) have been extensively investigated in the immune response of mammals. However, little is known about the involvement of MMP in abalone innate immune system against pathogen infection. In this study, the role of MMP-1 in the immune response of Pacific abalone (Haliotis discus hannai) was explored. The results showed that V. parahemolyticus infection induced significantly elevated expression of MMP-1 as well as immune related genes including allograft inflammatory factor 1 (AIF-1), macrophage expressed gene 1 (MPEG-1) and TPA-inducible sequence 11 family protein (Tis11FP). Notably, silencing of MMP-1 reduced the expression of these genes, suggesting that MMP-1 was an upstream regulatory factor in V. parahemolyticus infection. Further analysis showed that MMP-1 was engaged in the regulation of cellular (phagocytosis, apoptosis) and humoral [superoxide dismutase (SOD), alkaline phosphatase (ALP), acid phosphatase (ACP)] immunity. Interestingly, the extracellularly distributed MMP-1 could be translocated to the nuclei of hemocytes, thereby functioning as a transcriptional regulator or by selectively activating or inactivating other components through proteolysis. Hence, our study established an important role of MMP-1 in abalone innate immunity against V. parahemolyticus infection and it represented the first report on the investigation of MMP in abalone. Highlights • Induced expression of MMP-1 was observed after Vibrio parahemolyticus infection in Pacific abalone (Haliotis discus hannai). • MMP-1 was involved in the regulation of phagocytosis and apoptosis activities in abalone. • SOD, ALP and ACP activities were regulated by MMP-1 in abalone. • MMP-1 altered the expression of AIF-1, MPEG-1 and Tis11FP genes. • MMP-1 could be translocated into the nuclei of abalone hemocytes post bacterial infection. [ABSTRACT FROM AUTHOR]

Six new limonoids, named hainanxylogranolides A–F (1 – 6), together with nineteen known ones (7 – 25) were isolated from the seeds of a Hainan mangrove Xylocarpus granatum. The structures of the new compounds were established by extensive NMR spectroscopic data combined with the DFT and TDDFT calculated electronic circular dichroism spectra. Hainanxylogranolide A (1) is the aromatic B-ring limonoid containing a central pyridine ring and a C-17 substituted γ (21)-hydroxybutenolide moiety. Hainanxylogranolide B (2) belongs to the small group of mexicanolides containing a C 3 – O –C 8 bridge, whereas hainanxylogranolides C and D (3 and 4) are mexicanolides comprising a C 1 – O –C 8 bridge. Compounds 9 and 25 posed obvious inhibition effect on the tube formation of HUVECs. There are only about 25% tube-like structures were observed at the concentration of 40.0 μM of compound 25. The antiviral activities of the isolates against herpes simplex virus-1 (HSV-1) and severe fever with thrombocytopenia syndrome virus (SFTSV) were tested in vitro. Compound 23 exhibited moderate anti-SFTSV activity with the IC 50 value of 29.58 ± 0.73 μM. This is the first report of anti-angiogenic effect and anti-SFTSV activity of limonoids from the genus Xylocarpus. Hainanxylogranolides A–F: New Limonoids isolated from the seeds of Hainan mangrove plant Xylocarpus granatum. Wan-Shan Li, Xue-Ping Lei, Xin-Tong Yan, Yu-Yue Qin, Guang-Ying Chen, Song Li, and Zhong-Ping Jiang. [Display omitted] • Six new limonoids, named hainanxylogranolides A–F (1 – 6), together with nineteen known ones (7 – 25) were isolated from the seeds of Hainan Xylocarpus granatum. • Hainanxylogranolide A (1) is an unusual limonoid containing a central pyridine ring and a C-17 substituted γ (21)-hydroxybutenolide moiety. To data, only seven pyridine-containing limonoids have been reported. • C ompounds 9 and 25 posed obvious inhibition effect on the tube formation of HUVECs. • C ompound 23 exhibited moderate anti-SFTSV activity with the IC 50 value of 29.58 ± 0.73 μM. • This is the first report of anti-angiogenic effect and anti-SFTSV activity of limonoids from the genus Xylocarpus. [ABSTRACT FROM AUTHOR]

City planners are increasingly captivated by the possibilities of transforming urban spatial structures as an important strategy for reducing heat island intensity. This study addresses the mixed findings of polycentric urban spatial structures on surface urban heat island intensity, using a multiple regression method and pathway analysis for the city region and city proper in China. We found that the polycentric spatial structure can reduce the surface urban heat island intensity at the scale of both the city region and city proper, although the reduction was economically insignificant at the city region scale. Path analysis explained the reduction in surface urban heat island intensity in the city proper: polycentric structures disperse industrial firms to the "rural" areas and centralizes green spaces in the "urban" areas. Our findings may serve as references for policymakers when optimizing urban spatial structures to improve the thermal environment. • The polycentric structure can reduce the surface urban heat island intensity. • The polycentric structure disperses industrial firms to the suburbs. • The polycentric structure centralizes green spaces into the downtown area. • The polycentric city proper has a lower surface urban heat island intensity. [ABSTRACT FROM AUTHOR]

Background: Mestranol is a widely used estrogen, which is converted into its active metabolite ethinyl estradiol by cytochrome P450 (CYP) 2C9. To comprehensively examine the enzymatic activity of reported CYP2C9 variants in Chinese individuals in response to mestranol, wild-type CYP2C9*1 and 35 allelic variants were highly expressed in Sf21 insect cell microsomes and used for the detection of their enzymatic values in vitro. These results showed that the majority of tested variants exhibited decreased clearance values compared to wild type, except for CYP2C9*40 and *36. Method: Insect microsomes expressing the 36 CYP2C9 variants were incubated with 0.25-8 μmol/l mestranol for 30 min at 37°C. Then, the production of the metabolite of mestranol, ethinyl estradiol, was analyzed using high-performance liquid chromatography. Results: Most CYP-catalyzed reactions were sufficiently described by classical Michaelis-Menten kinetic parameters (e.g., Km and Vmax), while 9 variants exhibited atypical or non-Michaelis-Menten kinetic values, which were largely due to the self-inhibitory effectin response to mestranol. Conclusion: This is the first report of these rare alleles for mestranol metabolism, which provides fundamental data for further clinical studies on CYP2C9 alleles for mestranol metabolism. © 2015 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]

Objectives The aim of the present study was to explore the magnetic resonance imaging correlates of the performance of instrumental activities of daily living ( IADL) in patients with Alzheimer's disease combined with cerebrovascular disease. Methods A total of 66 patients with Alzheimer's disease combined with cerebrovascular disease formed the study sample. Two regression models were constructed to find correlates of IADL. Model 1 only included clinical variables and model 2 included both clinical and magnetic resonance imaging variables. Results In model 1, with IADL as the dependent variable, the Mini-Mental State Examination ( MMSE) score, Physical Self- Maintenance Scale score at baseline and age were significant correlates accounting for 40.1% of the variance of IADL at baseline. MMSE score and age were also significant correlates of IADL at 6 months, accounting for 38.1% of the variance of it. In model 2, severity of white matter lesions, MMSE and Physical Self- Maintenance Scale scores at baseline significantly correlated with IADL at baseline, accounting for 52.1% of the variance of the dependent variables; severity of white matter lesions and MMSE significantly correlated with IADL at 6 months, accounting for 41.5% of the variance of the dependent variables. Conclusion In patients with Alzheimer's disease combined with cerebrovascular disease, subcortical ischemic lesions might be significant contributor to the functional status. Geriatr Gerontol Int 2015; 15: 588-593. [ABSTRACT FROM AUTHOR]

Objective: To explore natural herbs to maintain the bactericidal activity of hydrogen peroxide (H). Methods: Eighteen extracts of Chinese herbs were prepared complying with the standard protocol. Each of the solutions was then mixed with 1% HO. The mixtures were handled with two approaches: autoclaved daily for one, two or three times; stored at room temperature from one through five years. Then the bactericidal activity were evaluated by assaying the minimal bactericidal concentration (MBC) and minimal inhibitory concentration (MIC) against Gram positive ( Staphylococcus aureus, ATCC25923) and Gram negative ( Escherichia coli, ATCC12421) bacteria. Results: While mixed with 1% HO, 10 out of 18 kinds of assessed Chinese herbs displayed MBC values at 1:12800 or higher after three times of autoclaving, and 8 of them preserved such level of MBC value after stored at room temperature for three years. Some Chinese herbs, i.e. R. Scutellariae, R. Coptidis, R. Bupleuri, H. Epimedii, C. Phelledendri and F. Chrysanthemi, can significantly maintain the bactericidal activity of diluted HO Conclusions: Certain Chinese herbs can effectively stabilize the bactericidal activity of HO undergoing autoclave or long-term storage. This paper reported a brandnew pharmaceutical function of Chinese herbs and provided experimental data for the potential enhancement of HO usage while its stability level is promoted. [ABSTRACT FROM AUTHOR]

In this paper, the gold grade series along drifts have been analyzed using two methods, rescaled range analysis and lacunarity analysis which are commonly used in nonlinear systems analysis. The aim of this study is to better understand the ore-forming processes and identify the local mineralized intensity and interactions that influence the spatial structure of gold element grade distribution, in the Dayingezhuang fault-controlled, disseminated-veinlet gold deposit in the Jiaodong gold province, eastern China. The result shows that the efficiency of two methods, in distinguishing between weakly mineralized, moderately mineralized and intensely mineralized of ore-forming area. It is obvious that the two parameters of both Hurst and lacunarity index in the weakly mineralized drifts are distinguished from those in the mineralized drifts, and the lower the index is, the more homogeneously distributed of the elements and the mineral intensity is relatively smaller. The methods used in this paper provide a relatively comprehensive description for local mineral intensity, offering an evidence for the identification of mineralization intensity and providing a guidance for further determination to the extent of deposit concentration and delineation of target mineralization zone. [ABSTRACT FROM AUTHOR]

The study examined the impact of spatial relationships on firm performance. It also assessed the impacts of network structural and relational characteristics on performance, as well as the moderating effects of these variables on the spatial relationship to performance linkages. The sample comprised 252 firms located in a mold industry cluster in the Zhejiang province of China. Both in-cluster ties and extra-cluster ties positively impacted performance. However, the effects of distant ties were more pronounced. Tie stability had a positive effect whereas tie quality had a negative effect on performance. Network centrality, tie strength, and tie stability strengthened the relationship between in-cluster ties and performance. By contrast, all network tie characteristics weakened and changed the form of the relationship between extra-cluster ties and performance. The findings suggest the need for cluster firms to consciously cultivate distant linkages in their network ties in order to neutralize the tendencies for lock-in and to arrest entropic deterioration in their respective clusters. [ABSTRACT FROM AUTHOR]

The article offers information on a study which focuses on the accumulation of age mass surrounding stagnation zones in nested flow systems. It informs that the study analyses the spatial distribution of model age around the stagnant zones in a series of drainage basins of different depth showing that groundwater age shows maximum value around each stagnation point. It also includes a case study to examine groundwater flow and age in the Ordos Plateau in northwestern China via carbon dating.

Understanding processes underlying spatial distribution of tree species is fundamental to studying species coexistence and diversity. This study modeled point patterns of tree distribution, expressed by Cartesian coordinates of individual trees within a mapped forest stand, for the purpose of identifying processes that may generate spatial patterns of tree communities. We used four primary point pattern processes (homogeneous Poisson process, inhomogeneous Poisson process, homogeneous Thomas process, and inhomogeneous Thomas process) to model tree distribution in two stem-mapped forests in Taiwan, Republic of China. These four models simulate spatial processes of habitat association and seed dispersal, allowing us to evaluate the potential contribution of habitat heterogeneity and dispersal limitation to the formation of spatial patterns of tree species. The results showed that the inhomogeneous Thomas process was the best fit model and described most of the species studied, suggesting that spatial patterns of tree species might be formed by the joint effects of habitat associations and dispersal limitation. The homogeneous Thomas process that models the effect of dispersal limitation was the second best model. We also found that the best fit models could be predicted by species attributes, including species abundance and dispersal mode. The significant traits, however, differed between the two study plots and demonstrated site-specific patterns. This study indicated that the interactive operation of niche-based (habitat heterogeneity) and neutral-based (dispersal limitation) may be important in generating spatial patterns of tree species in forest communities. [ABSTRACT FROM AUTHOR]

Great mineral intensity in drifts or drills is characterized by both the high proportion and spatial cluster of the high grades. Great mineral intensity indicates the high ore quality and low dilution in the exploitation. The fractal dimension, the fluctuation exponent proposed in this paper and the lacunarity are utilized to analyze the mineral intensity along drifts in the Dayingezhuang gold deposit in Jiaodong gold province, China. It is proven that the combination of the parameters can identify the mineral intensity. The fractal dimension and fluctuation exponent are negatively correlated. In the places where the fractal dimension is small and fluctuation exponent is great, the mineralization is more pronounced. While in the case that the fractal dimensions are similar, smaller fluctuation exponent means more clustered structure of high grades and greater mineral intensity. In the diagram of fractal dimension versus lacunarity, the drifts with great mineral intensity can also be identified. The methods used in this paper provide a relatively comprehensive description for local mineral intensity, providing information for both the ore-forming process and the exploitation. [ABSTRACT FROM AUTHOR]

Because of the relatively low soil moisture in arid or semi-arid regions, water vapour movement often predominates in the vadose zone and affects the partitioning of energy among various land surface fluxes. In an outdoor sand bunker experiment, the soil water content at 10 and 30 cm depth were measured at hourly intervals for 2.5 days during October 2004. It was found that the soil moisture reached the daily maximum value (5.9–6.1% at 10 cm and 11.9–13.1% at 30 cm) and minimum value (4.4–4.5% at 10 cm and 10.4–10.8% at 30 cm) at midday (0–1 p.m. for 10 cm and 2–3 p.m. for 30 cm) and before dawn (2–3 a.m. for 10 cm and 4–5 a.m. for 30 cm), respectively. The modified HYDRUS-1D code, which refers to the coupled water, water vapour and heat transport in soil, was used to simulate the moisture and water vapour flow in the soil. The numerical analyses provided insight into the diurnal movement of liquid water and water vapour driven by the gradients of pressure heads and temperatures in the subsurface zone. The simulated temperature and water content were in good agreement with the measured values. The spatial–temporal distribution of liquid water flux, water vapour flux and soil temperature showed a detailed diurnal pattern of soil water dynamics in relatively coarse sand. [ABSTRACT FROM AUTHOR]

Based on the datum line survey in August 2005 and June and August of 2006, water samples were collected in 30 sites to examine the trend of spatial distribution and temporal change of dissolved metals in seawater of Jinzhou Bay, China. The results showed that copper (Cu), lead (Pb), zinc (Zn), and cadmium (Cd) concentrations ranged from 1.71 to 3.49, 0.38 to 1.19, 21.77 to 39.16, and 1.65 to 2.01 μg/L, respectively. Except for Zn, the dissolved metal concentrations in August 2006 were much higher than those in August 2005. The concentrations in June 2006 were also higher than those in August 2006. The highest concentrations of dissolved metal were determined in samples collected from southwest of the Bay near sewage outfalls of Huludao Zinc Plant and Bohai Shipyard and the mouths of Wuli and Cishan rivers. The concentrations of dissolved metals increased inshore as compared with offshore. The principal contaminated factors were Zn, Cd, and Pb in the Jinzhou Bay. Significant positive correlations existed between the concentrations of Cu and Cd (0.016), as well as Zn and Cd (0.000). The overall results revealed that the Bohai Sea was one of the most contaminated areas by dissolved metals compared to other coastal areas in China. [ABSTRACT FROM AUTHOR]

Deforestation, over-development of water resources and population growth have contributed to degeneration of vegetation in the Heihe River Basin in northwest China. Salts and water contents are the most important factors affecting the growth of vegetation in this arid area. This study was conducted to determine soluble salt levels of soils in the unsaturated zone and the hydrochemistry of groundwater at 14 sites in this region. Concentrations of soluble ions in the soils deceased with depth. Soil ion contents increased at depths below the root system of native plants. Sulfate was the dominant anion in both the unsaturated zone and the groundwater. Total dissolved solids (TDS) in groundwater ranged from less than 1 g/L in the middle reaches of the watershed to about 10 g/L in the arid lower reaches. In the middle and upper reaches of the watershed, salinity in soil and groundwater decreased. Groundwater was highly variable in hydrochemistry. The lower reaches was predominated by SO4–Na•Mg and SO4–Mg•Na type water, whereas in the middle reaches groundwater is characterized by lower TDS and HCO3-dominated type water. Evapotranspiration is responsible for occurrence of the soluble salts in the soil profiles. Dissolution is the dominant chemical process in the middle reaches, whereas evapotranspiration prevails in the lower reaches of the Heihe River. [ABSTRACT FROM AUTHOR]

A unique regime of groundwater flow in large limestone aquifers in China is presented in the context of variation of anisotropy of permeability tensors with depth. The limestone aquifers are composed of an upper region where the permeability ellipsoid is upright or prolate and characterized by Kz>Kx and Kz>Ky, a transitional zone, and a lower zone whose permeability ellipsoid is horizontal or oblate and characterized by Kz

• bla CTX-M-27 in E. coli increasingly prevalent in humans in South Korea, Japan, China and Europe. • bla CTX-M-27 in Salmonella strains recently been described in food animals. • Tn 1721 -like structure harboring bla CTX-M-27 mobilize between Salmonella and Escherichia coli from food-producing animals. • From a "one health" perspective, measures are urgently needed to monitor and control its further spread. The aim of this study was to explore the characteristics of bla CTX-M-27 carriage and mobilization in Salmonella and Escherichia coli isolates from food-producing animals in China. A total of 2280 E. coli and 229 Salmonella isolates collected from food animals from June 2003 to September 2014 were screened for the presence of bla CTX-M-27 gene. The bla CTX-M-27 -positive isolates were typed and plasmid DNA sequenced to determine the genetic context of bla CTX-M-27 and plasmid types present. Bacterial fitness was evaluated by growth curve and plasmid stability in vitro. CTX-M-27-positive E. coli (18, 0.79 %) and Salmonella (34, 14.85 %) were detected. PFGE profiles of CTX-M-27-positive strains revealed a wide variety of genotypes and S. Indiana was the most prevalent serotype. Replicon typing, S1-PFGE and hybridization of CTX-M-27-carrying plasmids confirmed that bla CTX-M-27 gene was located on IncFII (12/18), IncN (4/18), and non-typeable (2/18) plasmids in E. coli and on P1-like bacteriophage (21/34), IncP (4/34), IncFIB (4/34), IncN (2/34), IncHI2 (2/34), and IncA/C (1/34) plasmids in Salmonella. Comparison and analysis of gene context of bla CTX-M-27 in P1-like bacteriophage and plasmids revealed they shared the same structure and contained an identical genetic context with the Tn 1721 -like structure ΔIS Ecp1B - bla CTX-M-27 -IS 903D - iroN -Δ map -Tn 1721. In addition, plasmid stability tests indicated that the bla CTX-M-27 P1-like bacteriophage were more stable than plasmids in the absence of cefotaxime selective pressure. These results demonstrate that Tn 1721 -like transposons harboring CTX-M-27 could be mobilized between different plasmids in E. coli and P1-like bacteriophage disseminated among Salmonella. [ABSTRACT FROM AUTHOR]

Background: Fourth branchial apparatus anomalies, are rare clinical entities, and present as complex cysts, sinuses and fistulae in the neck that can be difficult to manage. Methods: This is a retrospective review of a series of consecutive patients with fourth branchial apparatus anomalies treated at Department of Otolaryngology Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, from Apr 2014 to Nov 2019. Results: Ten patients with fourth branchial apparatus anomalies were identified, including 8 patients with fourth branchial fistula, and 2 patients with fourth branchial pouch sinus. There were 6 female patients and 4 male patients. Their age was from 6 years old to 39 years old (average age 20.4 years old, median age was 21 years old). All 8 fistulae were on the left side, while 2 pouch sinuses were both on the right side. Pre-operative examination with fiberoptic laryngoscope, barium swallow X-ray, CT or MRI identified internal orifice at pyriform fossa apex in 8 (80%) patients. All patients underwent challenging surgical resection by the senior author. Intra-operative direct laryngoscope confirmed or identified internal orifice in 9 (90%) patients. The tracts were all followed to the vicinity of inferior cornu of the thyroid cartilage and the cricothyroid space. Complete resection of cervical lesions and their attachment to hypopharynx were achieved in 9 cases. No complication occurred. One recurrence was detected, in the only patient whose internal orifice could not be located pre- or intra-operatively, and the hypopharyngeal attachment could not be removed. Conclusions: Direct laryngoscopy under general anesthesia is a reliable method of diagnosis for the fourth branchial apparatus anomalies. Complete surgical removal of fourth branchial apparatus anomalies, including their hypopharyngeal attachment, is the treatment of choice, and the key to prevent recurrence. [ABSTRACT FROM AUTHOR]

Mineral phenocrysts/megacrysts convey important information about deep magmatic evolution and volcanic eruption especially with respect to magmatic water content. Clinopyroxene (cpx) is generally considered to be less susceptible to diffusive hydrogen loss than olivine and orthopyroxene. We analyzed hydrogen concentration profiles alongside major and trace element compositions of a suite of cpx megacrysts (1–4 cm in size) hosted in basanitic scoria from the Gezi volcano, central Inner Mongolia of north China. The anhydrous composition within each megacryst is homogeneous, but comparison between different grains shows clear elemental covariation, suggesting that these cpx megacrysts progressively crystallized from a common parental magma. The cpx megacrysts contain hydrogen contents in the range of 0–410 wt ppm H 2 O at their cores, and some of them show a smooth decrease of hydrogen from the core to the rim. Those with the highest hydrogen contents (290–410 wt ppm H 2 O) have long plateau at the core, in contrast with long dehydration profiles and no plateau in some low-hydrogen megacrysts. These observations suggest that the cpx megacrysts experienced variable extent of dehydration during volcanic eruption, arising from variable H diffusivity probably associated with differences in the composition and microstructure of cpx megacrysts. Cpx megacrysts with the lowest degree of dehydration and good diffusion profiles are the most informative. Their plateau hydrogen contents at the core are used to infer ~2 wt% H 2 O in the parental magma. Quantitative modeling of the diffusion profiles at the rim yields a dehydration duration of 3–28 h, suggesting an ascent rate of 1–6 m/s for the host basanitic magma. • Profiles across cpx megacrysts show heterogeneous hydrogen distribution. • Differences in H contents and profiles indicate variable extent of dehydration. • Hydrogen content profiles are used to estimate ascent rates and yield 1–6 m/s. [ABSTRACT FROM AUTHOR]