4 results on '"Shen, Nan"'
Search Results
2. Health Disparities in Rheumatic Diseases: Understanding Global Challenges in Africa, Europe, Latin America, and Asia and Proposing Strategies for Improvement.
- Author
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Dey D, Sciascia S, Pons-Estel GJ, Ding H, and Shen N
- Subjects
- Africa epidemiology, Asia epidemiology, Europe epidemiology, Humans, Latin America epidemiology, Rheumatic Diseases epidemiology, Rheumatic Diseases therapy
- Abstract
Rheumatic diseases reach across continents with some similarities as well as unique challenges. The intersection between genetic factors, environmental exposures and socioeconomic factors, as well as challenges, with delays in access to subspecialty care and medications, manifest in different ways. By understanding both the challenges and successes in different countries, while also recognizing the significant diversity both within and across continents, unified strategies to improve rheumatic disease outcomes and decrease disparities among the most vulnerable groups can be developed and disseminated., Competing Interests: Disclosure The writers have no competing or conflict of interest to report. This article is based on work presented at the 13th Annual Lupus Conference (Lupus 2019) in April 2019 and the authors would like to acknowledge the conference organizer, Dr. Lindsey Criswell, for raising this important topic. Dr. Candace Feldman incorporated the continent-specific sections into a single article. There was no funding for this article., (Copyright © 2020 Elsevier Inc. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
3. Overview of lupus nephritis management guidelines and perspective from Asia.
- Author
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Mok CC, Yap DY, Navarra SV, Liu ZH, Zhao MH, Lu L, Takeuchi T, Avihingsanon Y, Yu XQ, Lapid EA, Lugue-Lizardo LR, Sumethkul V, Shen N, Chen SL, and Chan TM
- Subjects
- Asia, Cyclophosphamide therapeutic use, Humans, Immunosuppression Therapy, Lupus Nephritis classification, Lupus Nephritis immunology, Mycophenolic Acid analogs & derivatives, Mycophenolic Acid therapeutic use, Lupus Nephritis therapy, Practice Guidelines as Topic
- Abstract
Lupus nephritis (LN) is a common and important manifestation of systemic lupus erythematosus (SLE). Evidence suggests higher rates of lupus renal involvement in Asian populations, and maybe more severe nephritis, compared with other racial or ethnic groups. The management of LN has evolved considerably over the past three decades, based on observations from clinical studies that investigated different immunosuppressive agents including corticosteroids, cyclophosphamide, azathioprine, mycophenolic acid, calcineurin inhibitors and novel biologic therapies. This is accompanied by improvements in both the short-term treatment response rate and long-term renal function preservation. Treatment guidelines for LN have recently been issued by rheumatology and nephrology communities in U.S.A. and Europe. In view of the racial difference in disease manifestation and response to therapy, and the substantial disease burden in Asia, a panel of 15 nephrologists and rheumatologists from different Asian regions with extensive experience in lupus nephritis - the Steering Group for the Asian Lupus Nephritis Network (ALNN) - met and discussed the management of lupus nephritis in Asian patients. The group has also reviewed and deliberated on the recently published recommendations from other parts of the world. This manuscript summarizes the discussions by the group and presents consensus views on the clinical management and treatment of adult Asian patients with LN, taking into account both the available evidence and expert opinion in areas where evidence remains to be sought., (© 2013 The Authors. Nephrology © 2013 Asian Pacific Society of Nephrology.)
- Published
- 2014
- Full Text
- View/download PDF
4. Overview of lupus nephritis management guidelines and perspective from Asia.
- Author
-
Mok CC, Yap DY, Navarra SV, Liu ZH, Zhao MH, Lu L, Takeuchi T, Avihingsanon Y, Yu XQ, Lapid EA, Lugue-Lizardo LR, Sumethkul V, Shen N, Chen SL, and Chan TM
- Subjects
- Adult, Asia epidemiology, Asian People, Consensus, Drug Therapy, Combination, Evidence-Based Medicine standards, Guideline Adherence, Humans, Immunosuppressive Agents adverse effects, Lupus Nephritis diagnosis, Lupus Nephritis ethnology, Practice Patterns, Physicians' standards, Severity of Illness Index, Treatment Outcome, Immunosuppressive Agents therapeutic use, Lupus Nephritis drug therapy, Nephrology standards, Rheumatology standards
- Abstract
Lupus nephritis (LN) is a common and important manifestation of systemic lupus erythematosus (SLE). Evidence suggests higher rates of lupus renal involvement in Asian populations, and maybe more severe nephritis, compared with other racial or ethnic groups. The management of LN has evolved considerably over the past three decades, based on observations from clinical studies that investigated different immunosuppressive agents including corticosteroids, cyclophosphamide, azathioprine, mycophenolic acid, calcineurin inhibitors and novel biologic therapies. This is accompanied by improvements in both the short-term treatment response rate and long-term renal function preservation. Treatment guidelines for LN have recently been issued by rheumatology and nephrology communities in U.S.A. and Europe. In view of the racial difference in disease manifestation and response to therapy, and the substantial disease burden in Asia, a panel of 15 nephrologists and rheumatologists from different Asian regions with extensive experience in lupus nephritis - the Steering Group for the Asian Lupus Nephritis Network (ALNN) - met and discussed the management of lupus nephritis in Asian patients. The group has also reviewed and deliberated on the recently published recommendations from other parts of the world. This manuscript summarizes the discussions by the group and presents consensus views on the clinical management and treatment of adult Asian patients with LN, taking into account both the available evidence and expert opinion in areas where evidence remains to be sought., (© 2013 Asia Pacific League of Associations for Rheumatology and Wiley Publishing Asia Pty Ltd.)
- Published
- 2013
- Full Text
- View/download PDF
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