1. PROSPECTIVE RANDOMISED CONTROLLED STUDY ON EFFECT OF DEXMEDETOMIDINE AS AN ADJUVANT TO INTRATHECAL BUPIVACAINE ON DURATION OF POST-OPERATIVE ANALGESIA IN PATIENTS UNDERGOING LOWER ABDOMINAL SURGERIES.
- Author
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TIWARI, VINAMRA, TAMBEY, RANJEETA, and DESHPANDE, MUKUL S.
- Abstract
Introduction: spinal anaesthesia has emerged as a most popular technique for abdominal and lower abdominal surgeries for its safety, simplicity and effectivity. Adding adjuvants drugs to intrathecal local anaesthetics improves quality and duration of spinal blockade, and prolongs postoperative analgesia. Intrathecal dexmedetomidine with low-dose bupivacaine provides faster onset, prolonged sensory and motor block and reduced rescue analgesic requirement in patient undergoing TURP. Aims and objectives: To assess the Onset of sensory analgesia, onset of motor block, fixation time of sensory block, highest level of sensory block, quality of analgesia. Material and methods: This Prospective - Randomized study was conducted in the Anaesthesia Anaesthesia Department in Government Medical College, Nagpur from December 2018 to November 2020. 60 adult female patients between the age of 18 and 60 years participated in the study. The samples were equally divided into 2 groups, Group D-Case group-30 patients and Group B-Control group-30 patients. Intravenous cannula of 18/20 G was secured and patient was preloaded with 10ml/kg of Ringer lactate solution over 10-30 minutes. Baseline vital signs such blood pressure, pulse rate were recorded. Result: Maximum number of patients in group D and group B i. e 100% and 60% respectively had an excellent quality of analgesia during the procedure. Quality of analgesia was reported as satisfactory in 30% of patients and poor in 10% patients in group B. Quality of analgesia was found to be comparable in the two groups (p= 0.001). Thus, addition of dexmedetomidine only marginally improved quality of surgical analgesia in our study. Conclusion: Intrathecal inj. Dexmedetomidine 5mcg acts synergistically to potentiate intrathecal local anaesthetic bupivacaine with the result that there is relatively faster onset of sensory block and prolongation of both sensory and motor block. [ABSTRACT FROM AUTHOR]
- Published
- 2024