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Your search keyword '"Girone, Cinzia"' showing total 2 results
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2 results on '"Girone, Cinzia"'

1. Aptamer to ErbB-3/HER3 as innovative therapeutic agent in HNSCC.

Author

Pagano, Federica, Romaniello, Donatella, Girone, Cinzia, Morselli, Alessandra, Sgarzi, Michela, Mazzeschi, Martina, Borrelli, Francesco, Kuhre, Rikke Sophie, Filippini, Daria Maria, Presutti, Livio, Mahlknecht, Georg, and Lauriola, Mattia

Abstract

The article focuses on targeting the HER3 receptor axis in head and neck squamous cell carcinoma (HNSCC) patients who have acquired resistance to Cetuximab (CTX) treatment using an innovative aptamer drug (A33), which has shown promising results in downregulating HER3 and its downstream.

Published
2023

2. Mechanisms of resistance to last generation EGFR Inhibitors: hijacking NRG1/ERBB3 axis.

Author

Morselli, Alessandra, Romaniello, Donatella, Miroglio, Chiara, Girone, Cinzia, Sgarzi, Michela, Mazzeschi, Martina, Pagano, Federica, Kuhre, Rikke Sofie, Palladini, Arianna, Lollini, Pier-Luigi, Ardizzoni, Andrea, Yarden, Yosef, and Lauriola, Mattia

Abstract

The article focuses on the mechanisms of resistance to last-generation EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC) and highlights the role of the NRG1/ERBB3 axis in promoting resistance and tumor growth, suggesting potential therapeutic strategies.

Published
2023

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