Mechanisms of resistance to last generation EGFR Inhibitors: hijacking NRG1/ERBB3 axis.

Authors :: Morselli, Alessandra
Romaniello, Donatella
Miroglio, Chiara
Girone, Cinzia
Sgarzi, Michela
Mazzeschi, Martina
Pagano, Federica
Kuhre, Rikke Sofie
Palladini, Arianna
Lollini, Pier-Luigi
Ardizzoni, Andrea
Yarden, Yosef
Lauriola, Mattia
Source :: Italian Journal of Anatomy & Embryology / Archivio Italiano di Anatomia Ed Embriologia; 2023 Supplement, p90-90, 1p
Publication Year :: 2023
Abstract: The article focuses on the mechanisms of resistance to last-generation EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC) and highlights the role of the NRG1/ERBB3 axis in promoting resistance and tumor growth, suggesting potential therapeutic strategies.

Language :: English
ISSN :: 11226714
Database :: Complementary Index
Journal :: Italian Journal of Anatomy & Embryology / Archivio Italiano di Anatomia Ed Embriologia
Publication Type :: Academic Journal
Accession number :: 172226119

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