1. Phenolic content, antioxidant and anti-inflammatory activities of Tunisian Diplotaxis simplex (Brassicaceae).
- Author
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Oueslati S, Ellili A, Legault J, Pichette A, Ksouri R, Lachaal M, and Karray-Bouraoui N
- Subjects
- Animals, Cell Line, Flavonoids chemistry, Flowers chemistry, Macrophages drug effects, Mice, Nitric Oxide chemistry, Plant Extracts pharmacology, Proanthocyanidins chemistry, Anti-Inflammatory Agents pharmacology, Antioxidants pharmacology, Brassicaceae chemistry, Phenols chemistry, Plant Extracts chemistry
- Abstract
This study investigates the polyphenol content of Diplotaxis simplex extract and the biological activities of the main organ. The analysed extracts showed that polyphenol contents varied considerably as a function of organs. Furthermore, novel biological activities of this species were assessed. Flower extracts exhibit a potent in vitro antioxidant capacity using oxygen radical absorbance capacity and displayed a strong anti-inflammatory activity, inhibiting nitric oxide release, by 79.3% at 160 μg/mL. Our findings suggested that the Diplotaxis flower is a valuable source of antioxidants and anti-inflammatory agents.
- Published
- 2015
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