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Show the possibility of an alternative use of interventional radiology techniques in complex treatment of patients with inflammatory complications of the diverticular disease of the colon.In 2012-2016, there were 87 patients under our supervision with complicated diverticular disease. In 57 (65.5%) cases were diagnosed infiltrate, in 24 (27.6%) cases - abscess of paracolon area (Ib-II type by Hinchey), in 6 (6.9%) cases (III-IV type according Hinchey) generalized peritonitis have been identified.Emergency laparotomy was performed in 13 patients. Abscesses of paracolon (Ib-II type by Hinchey) area were diagnosed sonographically during the initial examination in 17 patients. 26 percutaneous drainage of diverticulogenous abscesses of different localizations self-locking drainage #8Fr 'pig tail' was carried out under the combined ultrasonic and X-ray control in this group of patients. The technical success of percutaneous drainaging of the abscesses was achieved in all manipulations. 13 patients had a single drainaging, and for diverticular disease - disease-free during the observation period of 1 year to 5 years. Resection of the colon in a planned manner after percutaneous drainage of recurrent abscess of paracolon area was performed in 4 patients. Complications related with the technique of installing drainage were not reported, mortality in the group of drained patients was absent.Ultrasound examination of patients with suspected inflammatory complications of diverticular disease - a necessary and sufficient method for initial diagnosis of the disease. Percutaneous drainage of diverticulogenous abscesses (Hinchey Ib-II) is represented by the pragmatic 'first line' choice in patients with complicated diverticular disease, that allows to treat the pathology steadfastly in most of the cases.Цель - показать возможность альтернативного применения методик интервенционной радиологии в комплексном лечении пациентов с воспалительными осложнениями дивертикулярной болезни ободочной кишки. Материал и методы. В 2012-2016 гг. под нашим наблюдением находились 87 пациентов с осложненным течением дивертикулярной болезни. У 57 (65,5%) больных был диагностирован инфильтрат, у 24 (27,6%) - параколярный абсцесс (Ib-II тип по Hinchey), у 6 (6,9%) - распространенный перитонит (III-IV тип по Hinchey) [5, 9]. Результаты. По экстренным показаниям лапаротомия была выполнена в 13 наблюдениях. У 17 пациентов с параколярными абсцессами (Ib-II тип по Hinchey) диагноз был установлен сонографически при первичном обследовании. В этой группе больных было выполнено 26 перкутанных дренирований дивертикулогенных абсцессов разных локализаций самофиксирующимся дренажем pig tail 8Fr под сочетанным ультразвуковым и рентгенологическим контролем. У 13 пациентов дренирование было однократным, а течение дивертикулярной болезни - безрецидивным за время наблюдения от 1 года до 5 лет. Резекция толстой кишки в плановом порядке после перкутанного дренирования рецидивного параколярного абсцесса была выполнена у 4 пациентов. Осложнений, связанных с техникой установки дренажа отмечено не было, случаев летального исхода после дренирования не было. Технический успех перкутанного дренирования полости дивертикулогенного абсцесса был достигнут во всех манипуляциях. Вывод. Ультразвуковое обследование пациентов с подозрением на воспалительные осложнения дивертикулярной болезни - необходимый и достаточный метод первичной диагностики заболевания. Перкутанное дренирование дивертикулогенных абсцессов (Hinchey Ib-II) представляется прагматичным методом выбора первой линии у пациентов с осложненной дивертикулярной болезнью, позволяющим в большинстве наблюдений стойко купировать осложнение.

Vascular bed of the infiltrating mammary gland carcinomas characterized by the incomplete maturity, atypia and polymorphism is studied electron microscopically. Two groups of vascular structures were investigated: avascular part represented by pseudovessels and vascular part with protocapillaries, capillaries, sinusoids and venulae that are distinguished by their morphofunctional properties and the degree of maturity. The vascular bed is characterized by a structural and functional heterogeneity. Ultrastructural properties characterizing the stages of the vascular bed morphogenesis are presented: angiogenesis activation, relative vascular differentiation and regression of some parts which occur asynchronically and are due to the properties of the stromal parenchymal relations in different microareas, and to the heterogeneity of the tumour on the whole.

The electron-microscopic study of skin cylindroma indicates that these tumors derive from the sweat glands, apparently the apocrine glands, and cells of the tumor and fibroblasts of the stroma take part in the formation of hyaline substance.

Kidney biopsies from 18 patients with primary gout were studied. Glomerular changes were found in all cases along with alterations in tubuli and vessels and stromal sclerosis. They were characterized by local thickening of basal membranes of capillaries, increase in the mesangial matrix, focal or diffuse proliferation of mesangial and endothelial cells of various degree of severity. Proliferation and activation of endothelial cells, mesangiocytes, podocytes, signs of podocyte damage, were found electron-microscopically. Subendothelial lucid zones were observed in the basal membrane, possibly at the site of uric acid deposits. The above described alterations resemble those in focal mesangio-capillary or mesangial proliferative glomerulonephritis.