1. The Influence of Neurological Disorders Before Cardiac Myxoma Surgery on the Rate of Postoperative Recurrences: Analysis of 317 Patients in a Single Center
- Author
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Byul Hee Yoon, Wonhyoung Park, Jae Sung Ahn, Jung Cheol Park, Joonho Byun, M. H. Kim, and Seungjoo Lee
- Subjects
medicine.medical_specialty ,business.industry ,Incidence (epidemiology) ,Medical record ,Myxoma ,Disease ,medicine.disease ,Single Center ,Surgery ,Heart Neoplasms ,Postoperative Complications ,Aneurysm ,Recurrence ,cardiovascular system ,medicine ,Humans ,cardiovascular diseases ,Neurology (clinical) ,Nervous System Diseases ,Adverse effect ,business ,Retrospective Studies ,Rare disease - Abstract
Background and Purpose Cardiac myxoma is a very rare disease for which resection is the treatment gold standard. There are many neurologic manifestations associated with this disease, including embolic infarctions, arterial aneurysms, and brain metastatic myxomas, but few large-scale studies have addressed this. We here retrospectively analyzed the incidence, type, and prognosis of these neurologic disorders. Methods We enrolled 317 patients who received a cardiac myxoma resection between 2004 and 2019 at our institution. A retrospective review of the medical records and radiologic imaging was performed for each patient, and various clinical factors were compared and analyzed with regard to clinical outcomes and the incidence of adverse events. Results Patients with a neurologic disorder before surgery were found to be more likely to develop new postoperative neurologic complications (p = .003). Patients with neurologic disorder arising at any time before or after surgery had poorer outcomes (p Conclusion The clinical management of cardiac myxoma must take account of neurologic sequelae independently of the surgical intervention to remove the lesion. Cardiac myxoma patients with any neurologic disorder should undergo both neurosurgical follow-up as well as cardiac surgical follow-up, even if myxoma removal surgery has been performed. We suggest that that active neuroimaging during long term follow-up is essential in these cases.
- Published
- 2022