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Intracranial Stenting of Severe Symptomatic Intracranial Stenosis: Results of 100 Consecutive Patients
- Source :
- AJNR Am J Neuroradiol
- Publication Year :
- 2008
- Publisher :
- American Society of Neuroradiology (ASNR), 2008.
-
Abstract
- BACKGROUND AND PURPOSE: There are a few reports regarding the outcome evaluation of balloon-expandable intracranial stent placement (BEICS). The purpose of our study was to evaluate the outcome and factors related to the adverse events (AEs) of BEICS. MATERIALS AND METHODS: We evaluated 100 consecutive patients who underwent BEICS. We assessed the procedural success (residual stenosis 50%) at 6 months. We also analyzed 18 factors including symptom patterns related to AE rate. Symptom patterns revealed 1) stable patients (n = 73) with improving, stationary, or resolved symptoms; and 2) unstable patients (n = 27) with gradual worsening or fluctuating symptoms (National Institutes of Health Stroke Scale [NIHSS] ≥4) within 2 days before stent placement. RESULTS: The procedural success rate was 99%. Overall, there were 10 (10%) AEs within the 6 months: 4 (4%) minor strokes, 3 (3%) major strokes, and 3 (3%) deaths including a death from myocardial infarction. AE rate was 4.1% in stable and 25.9% in unstable patients. Restenosis at 6 months revealed 0% (0/59). Good outcome (modified Rankin Scale ≤2) at 6 months was 97% (71/73) in stable and 67% (18/27) in unstable patients. Stepwise logistic regression model revealed that symptom pattern (unstable versus stable) was the only significant risk factor (OR, 8.167; 95% CI, 1.933–34.500; P = .004). CONCLUSION: BEICS revealed a low AE and good outcome rate at 6 months, especially in the stable patients. Midterm outcome was also favorable in the unstable patient group.
- Subjects :
- Adult
Male
Middle Cerebral Artery
medicine.medical_specialty
medicine.medical_treatment
Constriction, Pathologic
Constriction
Restenosis
Modified Rankin Scale
Angioplasty
medicine
Humans
Radiology, Nuclear Medicine and imaging
Myocardial infarction
Adverse effect
Vertebral Artery
Aged
Aged, 80 and over
Interventional
business.industry
Middle Aged
Stepwise regression
Intracranial Arteriosclerosis
medicine.disease
Surgery
Stroke
Stenosis
Basilar Artery
Female
Stents
Neurology (clinical)
business
Angioplasty, Balloon
Carotid Artery, Internal
Subjects
Details
- ISSN :
- 1936959X and 01956108
- Volume :
- 29
- Database :
- OpenAIRE
- Journal :
- American Journal of Neuroradiology
- Accession number :
- edsair.doi.dedup.....3330929009e53c65f8cdd299bc27eb0b