1. Le sarcome granulocytaire, un diagnostic à connaître : à propos de 3 observations pédiatriques
- Author
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Yves Bertrand, V. Mialou, Frédérique Dijoud, C Rénard, Sandrine Girard, J.-M. André, and J P Pracros
- Subjects
Chemotherapy ,Pathology ,medicine.medical_specialty ,medicine.diagnostic_test ,Acute myeloblastic leukemia ,business.industry ,Intestinal Neoplasm ,medicine.medical_treatment ,Disease ,medicine.disease ,medicine.anatomical_structure ,hemic and lymphatic diseases ,Pediatrics, Perinatology and Child Health ,Biopsy ,medicine ,Immunohistochemistry ,Bone marrow ,Sarcoma ,business ,neoplasms - Abstract
Granulocytic sarcoma (GS) is a rare extramedullary tumor frequently associated with acute myeloblastic leukemia (AML). We report 3 cases of pediatric granulocytic sarcomas with various locations: skin, orbit, and bowel. Cases 1 and 2 were associated with AML; case 3 was isolated. In all 3 cases, the diagnosis was delayed or initially missed. Pathology and immunohistochemistry data identified the disease. GS is treated with chemotherapy, like AML. The prognosis of GS seems better than that of isolated AML.
- Published
- 2010