1,851 results on '"A. Kotani"'
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2. Impact of Tumor Progression on Survival During Neoadjuvant Chemotherapy in Breast Cancer: A Cohort Study
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Hiroji Iwata, Masaya Hattori, Nanae Horisawa, Yuka Endo, Daiki Takatsuka, Yuri Ozaki, Akiyo Yoshimura, Masataka Sawaki, Ayumi Kataoka, Kazuki Nozawa, and Haruru Kotani
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Oncology ,medicine.medical_specialty ,Chemotherapy ,Cancer Research ,business.industry ,medicine.medical_treatment ,Breast Neoplasms ,General Medicine ,medicine.disease ,Neoadjuvant Therapy ,Cohort Studies ,Breast cancer ,Tumor progression ,Internal medicine ,Antineoplastic Combined Chemotherapy Protocols ,medicine ,Humans ,Female ,business ,Retrospective Studies ,Cohort study - Abstract
Background: Although few patients with breast cancer experience tumor progression during neoadjuvant systemic therapy (NST), their extremely poor outcomes are similar to patients who fail to achieve pathological complete response (pCR). No reports have compared patients with pCR, non-pCR, and progression during NST to determine the survival outcomes.Methods: This retrospective chart review of patients with stage I–III breast cancer was conducted between January 2001 and December 2018. pCR was defined as no invasive cancer or in situ residuals in the breast and lymph nodes (ypT0 ypN0). Disease-free survival (DFS) and overall survival (OS) were estimated using Kaplan–Meier methods.Results: Of the 595 patients who received NST, 167 (29.2%) had pCR (pCR group), 404 (70.8%) responded to NST but did not have pCR (non-pCR group), and 24 (4.0%) experienced tumor progression during NST (PD group). The median DFS was 6.0 months, 154.0 months, and not reached in the PD, non-pCR, and pCR groups, respectively. The PD group had significantly shorter DFS than patients without tumor progression in the pCR and non-pCR groups [hazard ratios (HR) 13.0, 95% CI: 8.1–21.0, p < 0.01]. The median OS was 13.6 months (95% CI: 10.4–35.5) in the PD group and was not reached in the pCR and non-pCR (non-PD) groups. The OS was significantly poorer in the PD group than in the non-PD group (HR 15.8, 95% CI: 9.2–27.1, p < 0.01).Conclusion: The PD group had the poorest survival outcomes even after recurrence, thus warranting new treatment targets.
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- 2022
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3. Impact of pulmonary artery coarctation on pulmonary artery growth and definitive repair following modified Blalock–Taussig shunt
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Yosuke Kuroko, Junko Kobayashi, Yasuhiro Kotani, Takuya Kawabata, Shingo Kasahara, Sachiko Kadowaki, Yasuyuki Kobayashi, and Eiri Kisamori
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Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Constriction, Pathologic ,Pulmonary Artery ,Aortic Coarctation ,Chart review ,Ductus arteriosus ,medicine.artery ,Internal medicine ,Humans ,Medicine ,In patient ,Blalock-Taussig Procedure ,Ductus Arteriosus, Patent ,Retrospective Studies ,business.industry ,Infant, Newborn ,medicine.disease ,Stenosis ,medicine.anatomical_structure ,Modified Blalock-Taussig shunt ,Concomitant ,Pulmonary artery ,Cardiology ,Surgery ,Cardiology and Cardiovascular Medicine ,business ,Shunt (electrical) - Abstract
Pulmonary artery coarctation may pose a risk for pulmonary stenosis and subsequent failure to achieve definitive repair. We sought to assess the impact of pulmonary artery coarctation on pulmonary artery growth.A retrospective chart review was performed in 130 patients, including 37 single ventricles with a modified Blalock-Taussig shunt as first palliation. Pulmonary artery coarctation was defined as discrete stenosis of the pulmonary artery, with a diameter of less than 3 mm and with the ductus arteriosus connected. Preoperative echocardiography showed pulmonary artery coarctation in 29 patients (22%). Concomitant pulmonary artery plasty was performed in 14 patients with discrete stenosis having a diameter of less than 2 mm.Pre-modified Blalock-Taussig shunt left pulmonary artery z-scores were lower in patients with pulmonary artery coarctation than in those without (-4.0 [-5.8, -2.1] vs -1.7 [-2.6, -0.8], P .001), and this remained the same even after modified Blalock-Taussig shunt (-2.5 [-5.1, -0.5] vs -0.5 [-2.4, 0.8], P = .010). Concomitant pulmonary artery plasty did not result in catch-up growth of the left pulmonary artery (post-modified Blalock-Taussig shunt left pulmonary artery z-score in patients with pulmonary artery plasty: -3.0 (-6.5, -2.0) versus those without: -1.8 (-3.3, -0.3), P = .279). Definitive repair/Fontan completion was achieved in 111 patients (85%), and this was not affected by the presence of pulmonary artery coarctation.Pulmonary artery coarctation affected disproportionate pulmonary artery growth throughout the staged repair, but did not result in failure of definitive repair/Fontan completion. Pulmonary artery plasty during the neonatal period did not contribute to catch-up growth of the left pulmonary artery; therefore, surgical indications and timing should be carefully considered.
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- 2022
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4. The Optimal Anatomical Position and Threshold Temperature of a Temperature Data Logger for Brace-Wearing Compliance in Patients with Scoliosis
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Shohei Minami, Tomoyuki Asada, Yu Sasaki, Toshiaki Kotani, Tsuyoshi Sakuma, Shunji Kishida, Hiromi Kimura, Kazuhide Inage, Minako Osaki, Masashi Yamazaki, Yasushi Iijima, Tsutomu Akazawa, Kotaro Sakashita, Yuri Ichikawa, Keita Nakayama, Kosuke Sato, Masao Koda, Yasuhiro Shiga, Seiji Ohtori, and Takahiro Sunami
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Orthodontics ,business.industry ,Scoliosis ,medicine.disease ,Brace ,Compliance (physiology) ,Standard anatomical position ,Threshold temperature ,Medicine ,Orthopedics and Sports Medicine ,Surgery ,In patient ,Neurology (clinical) ,business ,Temperature data logger - Abstract
Although strict compliance with brace wearing is important for patients with scoliosis, no study has analyzed the most ideal conditions for temperature logger accuracy. We evaluated the optimal brace position and threshold temperature for the logger and determined the reliability of its measurements in patients with scoliosis.Five temperature loggers were embedded into holes generated at five different brace positions (right scapula, right chest, left chest, lumbar, and abdomen) within the brace. We compared measurement errors at each position using different threshold temperatures to determine the ideal anatomical position and threshold temperature. Under the ideal conditions determined, we calculated the reliability of the temperature logger readings in three healthy participants.Measurement errors (i.e., differences between the actual and logger-recorded brace wearing times) were the lowest at the 28°C and 30°C threshold temperatures when the logger was positioned at the left chest and at 30°C at the abdomen. Among these three temperature/position combinations, we considered the abdomen to be the least affected by the shape of the brace; thus, the placement of the temperature logger at the abdomen using a threshold temperature of 30°C was the most ideal condition.The placement of the temperature logger at the abdomen using a threshold temperature of 30°C was the most ideal condition, with the reliability of the logger being 97.9%±0.9%. This information might be useful for scoliosis management teams, and this temperature logger provides a valuable clinical tool.
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- 2022
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5. A novel definition and treatment of hyperinflammation in COVID-19 based on purinergic signalling
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Atsuko Shono, Coenraad K van Kalken, Peter J. van der Spek, Eric P Krenning, Toru Kotani, Djo Hasan, and Pathology
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Male ,Programmed cell death ,Critical Care ,Maximum Tolerated Dose ,Purinergic P2X Receptor Antagonists ,Secondary infection ,Anti-Inflammatory Agents ,Inflammation ,Hyperinflammation ,Cytokine storm ,Infusions, Subcutaneous ,T-Lymphocytes, Regulatory ,Lymphatic System ,Cellular and Molecular Neuroscience ,Immune system ,P2X7 receptor antagonist ,Adenosine Triphosphate ,Medicine ,Humans ,Molecular Biology ,Respiratory Distress Syndrome ,business.industry ,Purinergic receptor ,Models, Immunological ,Receptors, Purinergic ,Receptors, Purinergic P1 ,COVID-19 ,Lidocaine ,Cell Biology ,Purinergic signalling ,Middle Aged ,medicine.disease ,Lymphatic system ,Immunology ,Commentary ,Lymph Nodes ,Receptors, Purinergic P2X7 ,medicine.symptom ,business ,Cytokine Release Syndrome ,Lidocaine base ,Immune paralysis ,Signal Transduction - Abstract
Hyperinflammation plays an important role in severe and critical COVID-19. Using inconsistent criteria, many researchers define hyperinflammation as a form of very severe inflammation with cytokine storm. Therefore, COVID-19 patients are treated with anti-inflammatory drugs. These drugs appear to be less efficacious than expected and are sometimes accompanied by serious adverse effects. SARS-CoV-2 promotes cellular ATP release. Increased levels of extracellular ATP activate the purinergic receptors of the immune cells initiating the physiologic pro-inflammatory immune response. Persisting viral infection drives the ATP release even further leading to the activation of the P2X7 purinergic receptors (P2X7Rs) and a severe yet physiologic inflammation. Disease progression promotes prolonged vigorous activation of the P2X7R causing cell death and uncontrolled ATP release leading to cytokine storm and desensitisation of all other purinergic receptors of the immune cells. This results in immune paralysis with co-infections or secondary infections. We refer to this pathologic condition as hyperinflammation. The readily available and affordable P2X7R antagonist lidocaine can abrogate hyperinflammation and restore the normal immune function. The issue is that the half-maximal effective concentration for P2X7R inhibition of lidocaine is much higher than the maximal tolerable plasma concentration where adverse effects start to develop. To overcome this, we selectively inhibit the P2X7Rs of the immune cells of the lymphatic system inducing clonal expansion of Tregs in local lymph nodes. Subsequently, these Tregs migrate throughout the body exerting anti-inflammatory activities suppressing systemic and (distant) local hyperinflammation. We illustrate this with six critically ill COVID-19 patients treated with lidocaine.
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- 2022
6. Soluble programmed cell death-1 predicts hepatocellular carcinoma development during nucleoside analogue treatment
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Hiroyuki Motoyama, Norifumi Kawada, Kohei Kotani, Akihiro Tamori, Naoshi Odagiri, Hideki Fujii, Hoang Hai, Le Thi Thanh Thuy, Atsushi Hagihara, Minh Phuong Dong, Masaru Enomoto, Ritsuzo Kozuka, Etsushi Kawamura, Sawako Uchida-Kobayashi, and Kanako Yoshida
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Adult ,Male ,Carcinoma, Hepatocellular ,Guanine ,Time Factors ,Science ,Fluoroimmunoassay ,Programmed Cell Death 1 Receptor ,Antiviral Agents ,Article ,Hepatitis ,Young Adult ,Hepatitis B, Chronic ,Predictive Value of Tests ,Programmed cell death 1 ,medicine ,Humans ,Viral hepatitis ,Aged ,Multidisciplinary ,biology ,Nucleoside analogue ,Hepatology ,business.industry ,Liver Neoplasms ,Gastroenterology ,Nucleosides ,Middle Aged ,medicine.disease ,Treatment Outcome ,Hepatocellular carcinoma ,biology.protein ,Cancer research ,Medicine ,Female ,business ,Biomarkers ,medicine.drug - Abstract
Soluble immune checkpoint molecules are emerging novel mediators of immune regulation. However, it is unclear whether soluble immune checkpoint proteins affect the development of hepatocellular carcinoma (HCC) during nucleos(t)ide analogue (NA) treatment in patients with chronic hepatitis B virus infection. This study included 122 NA-naïve patients who received NA therapy. We assessed the associations of clinical factors, including soluble immune checkpoint proteins, with HCC development during NA treatment. The baseline serum concentrations of 16 soluble immune checkpoint proteins were measured using multiplexed fluorescent bead-based immunoassay. In total, 13 patients developed HCC during the follow-up period (median duration, 4.3 years). Of the 16 proteins, soluble inducible T-cell co-stimulator (≥ 164.71 pg/mL; p = 0.014), soluble programmed cell death-1 (sPD-1) (≤ 447.27 pg/mL; p = 0.031), soluble CD40 (≤ 493.68 pg/mL; p = 0.032), and soluble herpes virus entry mediator (≤ 2470.83 pg/mL; p = 0.038) were significantly associated with HCC development (log-rank test). In multivariate analysis, an sPD-1 level ≤ 447.27 pg/mL (p = 0.014; hazard ratio [HR], 4.537) and α-fetoprotein level ≥ 6.4 ng/mL (p = 0.040; HR, 5.524) were independently and significantly associated with HCC development. Pre-treatment sPD-1 is a novel predictive biomarker for HCC development during NA treatment.
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- 2022
7. Prevalence and risk factors of labor-onset hypertension: A multicenter study in Japan
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Shigeru Yoshida, Tomoko Nakano-Kobayashi, Hiroaki Kajiyama, Kenji Imai, Yoshinori Moriyama, Tomomi Kotani, Mamoru Yamashita, Takafumi Ushida, Yukako Iitani, and Noriyuki Nakamura
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Adult ,medicine.medical_specialty ,Blood Pressure ,Severity of Illness Index ,Preeclampsia ,Pregnancy ,Risk Factors ,Prevalence ,Internal Medicine ,Humans ,Medicine ,Stroke ,Retrospective Studies ,Eclampsia ,business.industry ,Obstetrics ,Postpartum Period ,Obstetrics and Gynecology ,Retrospective cohort study ,Hypertension, Pregnancy-Induced ,Delivery, Obstetric ,medicine.disease ,stomatognathic diseases ,Blood pressure ,Female ,Maternal death ,business ,Body mass index - Abstract
Objectives To investigate the prevalence and risk factors of labor-onset hypertension (LOH), defined as hypertension first detected during labor among women without hypertension prior to admission for labor. Study design In this multicenter retrospective study, clinical data of women who delivered vaginally at term between 2012 and 2018 were collected from 12 primary maternity care units. Blood pressure was measured at five time points from admission to 2 h postpartum in a total of 30,129 normotensive women at the last prenatal check-up. LOH was defined as systolic blood pressure (SBP) of ≥ 140 mmHg or diastolic blood pressure (DBP) of ≥ 90 mmHg during the first to fourth stages of labor. Main outcome measures Multivariate regression analyses were conducted to evaluate the risk factors of LOH and severe LOH (SBP of ≥ 160 mmHg or DBP of ≥ 110 mmHg). Results Among the 30,129 women, 8,565 (28.4%) presented with LOH and 734 (2.4%) with severe LOH. The prevalence of LOH was the highest at the second stage of labor (21.7%) and decreased rapidly after delivery. The independent risk factors of LOH were maternal age of ≥ 35 years, pre-pregnancy body mass index of ≥ 25 kg/m2, and pregnancy weight gain of ≥ 15 kg. Conclusion LOH is common, with approximately one in four women experiencing LOH during labor and early postpartum. Meanwhile, severe LOH occurred in 2.4% of the pregnancies. Closer blood pressure monitoring during labor may enable obstetric caregivers to recognize LOH in a timely manner and reduce maternal adverse outcomes, such as eclampsia and stroke.
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- 2021
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8. Stroke prevention in patients from Latin American countries with non‐valvular atrial fibrillation: Insights from the GARFIELD‐AF registry
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Jerjes-Sanchez C., Corbalan R., Barretto A. C. P., Luciardi H. L., Allu J., Illingworth L., Pieper K. S., Kayani G., Fitzmaurice D. A., Goto S., Hacke W., Mantovani L. G., Turpie A. G. G., Gersh B. J., Gibbs H., Brodmann M., Cools F., Connolly S. J., Spyropoulos A., Eikelboom J., Hu D., Jansky P., Nielsen J. D., Ragy H., Raatikainen P., Le Heuzey J. -Y., Darius H., Keltai M., Kakkar S., Sawhney J. P. S., Agnelli G., Ambrosio G., Koretsune Y., Diaz C. J. S., ten Cate H., Atar D., Stepinska J., Panchenko E., Lim T. W., Jacobson B., Oh S., Vinolas X., Rosenqvist M., Steffel J., Angchaisuksiri P., Parkhomenko A., Al Mahmeed W., Chen K. N., Zhao Y. S., Zhang H. Q., Chen J. Z., Cao S. P., Wang D. W., Yang Y. J., Li W. H., Yin Y. H., Tao G. Z., Yang P., Chen Y. M., He S. H., Wang Y., Fu G. S., Li X., Wu T. G., Cheng X. S., Yan X. W., Zhao R. P., Chen M. S., Xiong L. G., Chen P., Jiao Y., Guo Y., Xue L., Wang F. Z., Li H., Yang Z. M., Bai C. L., Chen J., Chen J. Y., Chen X., Feng S., Fu Q. H., Gao X. J., Guo W. N., He R. H., He X. A., Hu X. S., Huang X. F., Li B., Li J., Li L., Li Y. H., Liu T. T., Liu W. L., Liu Y. Y., Lu Z. C., Luo X. L., Ma T. Y., Peng J. Q., Sheng X., Shi X. J., Sun Y. H., Tian G., Wang K., Wang L., Wu R. N., Xie Q., Xu R. Y., Yang J. S., Yang L. L., Yang Q., Ye Y., Yu H. Y., Yu J. H., Yu T., Zhai H., Zhan Q., Zhang G. S., Zhang Q., Zhang R., Zhang Y., Zheng W. Y., Zhou B., Zhou Z. H., Zhu X. Y., Jadhav P., Durgaprasad R., Ravi Shankar A. G., Rajput R. K., Bhargava K., Sarma R., Srinivas A., Roy D., Nagamalesh U. M., Chopda M., Kishore R., Kulkarni G., Chandwani P., Pothiwala R. A., Padinhare Purayil M., Shah S., Chawla K., Kothiwale V. A., Raghuraman B., Vijayaraghavan G., Vijan V. M., Bantwal G., Bisne V., Khan A., Gupta J. B., Kumar S., Jain D., Abraham S., Adak D., Barai A., Begum H., Bhattacharjee P., Dargude M., Davies D., Deshpande B., Dhakrao P., Dhyani V., Duhan S., Earath M., Ganatra A., Giradkar S., Jain V., Karthikeyan R., Kasala L., Kaur S., Krishnappa S., Lawande A., Lokesh B., Madarkar N., Meena R., More P., Naik D., Prashanth K., Rao M., Rao N. M., Sadhu N., Shah D., Sharma M., Shiva P., Singhal S., Suresh S., Vanajakshamma V., Panse S. G., Kanamori S., Yamamoto K., Kumagai K., Katsuda Y., Sadamatsu K., Toyota F., Mizuno Y., Misumi I., Noguchi H., Ando S., Suetsugu T., Minamoto M., Oda H., Shiraishi K., Adachi S., Chiba K., Norita H., Tsuruta M., Koyanagi T., Ando H., Higashi T., Okada K., Azakami S., Komaki S., Kumeda K., Murayama T., Matsumura J., Oba Y., Sonoda R., Goto K., Minoda K., Haraguchi Y., Suefuji H., Miyagi H., Kato H., Nakamura T., Nandate H., Zaitsu R., Fujiura Y., Yoshimura A., Numata H., Ogawa J., Tatematsu H., Kamogawa Y., Murakami K., Wakasa Y., Yamasawa M., Maekawa H., Abe S., Kihara H., Tsunoda S., Saito K., Fudo T., Obunai K., Tachibana H., Oba I., Kuwahata T., Higa S., Gushiken M., Eto T., Yoshida H., Ikeda D., Ishizawa M., Nakatsuka M., Murata K., Ogurusu C., Shimoyama M., Akutsu M., Takamura I., Hoshino F., Yokota N., Iwao T., Tsuchida K., Takeuchi M., Hatori Y., Kitami Y., Nakamura Y., Oyama R., Ageta M., Go Y., Mishima K., Unoki T., Morii S., Shiga Y., Sumi H., Nagatomo T., Sanno K., Fujisawa K., Atsuchi Y., Nagoshi T., Seto T., Tabuchi T., Kameko M., Nii K., Oshiro K., Takezawa H., Nagano S., Miyamoto N., Iwaki M., Fujii M., Okawa M., Abe M., Saito T., Mito T., Nagao K., Minami J., Mita T., Sakuma I., Taguchi T., Marusaki S., Doi H., Tanaka M., Fujito T., Matsuta M., Kusumoto T., Kakinoki S., Ashida K., Yoshizawa N., Agata J., Arasaki O., Manita M., Ikemura M., Fukuoka S., Murakami H., Matsukawa S., Hata Y., Taniguchi T., Ko T., Kubo H., Imamaki M., Akiyama M., Inagaki M., Odakura H., Ueda T., Katsube Y., Nakata A., Watanabe H., Techigawara M., Igarashi M., Taga K., Kimura T., Tomimoto S., Shibuya M., Nakano M., Ito K., Seo T., Hiramitsu S., Hosokawa H., Hoshiai M., Hibino M., Miyagawa K., Horie H., Sugishita N., Soma A., Neya K., Yoshida T., Mizuguchi M., Ishiguro M., Minagawa T., Wada M., Mukawa H., Okuda F., Nagasaka S., Abe Y., Adachi T., Akahane K., Amano T., Aoki K., Aoyama T., Arai H., Arima S., Arino T., Asano H., Asano T., Azuma J., Baba T., Betsuyaku T., Chibana H., Date H., Doiuchi J., Emura Y., Endo M., Fujii Y., Fujiki R., Fujisawa A., Fujisawa Y., Fukuda T., Fukui T., Furukawa N., Furukawa T., Furumoto W., Goto T., Hamaoka M., Hanazono N., Hasegawa K., Hatsuno T., Hayashi Y., Higuchi K., Hirasawa K., Hirayama H., Hirose M., Hirota S., Honda M., Ido T., Iiji O., Ikeda H., Ikeda K., Ikeoka K., Imaizumi M., Inaba H., Inoue T., Iseki F., Ishihara A., Ishioka N., Ito N., Iwase T., Kakuda H., Kamata J., Kanai H., Kanda H., Kaneko M., Kano H., Kasai T., Kato T., Kato Y., Kawada Y., Kawai K., Kawakami K., Kawakami S., Kawamoto T., Kawano S., Kim J., Kira T., Kitazawa H., Kitazumi H., Kito T., Kobayashi T., Koeda T., Kojima J., Komatsu H., Komatsu I., Koshibu Y., Kotani T., Kozuka T., Kumai Y., Kumazaki T., Maeda I., Maeda K., Maruyama Y., Matsui S., Matsushita K., Matsuura Y., Mineoi K., Mitsuhashi H., Miura N., Miyaguchi S., Miyajima S., Miyamoto H., Miyashita A., Miyata S., Mizuguchi I., Mizuno A., Mori T., Moriai O., Morishita K., Murai O., Nagai S., Nagata E., Nagata H., Nakagomi A., Nakahara S., Nakamura M., Nakamura R., Nakanishi N., Nakayama T., Nakazato R., Nanke T., Nariyama J., Niijima Y., Niinuma H., Nishida Y., Nishihata Y., Nishino K., Nishioka H., Nishizawa K., Niwa I., Nomura K., Nomura S., Nozoe M., Ogawa T., Ohara N., Okada M., Okamoto K., Okita H., Okuyama M., Ono H., Ono T., Pearce Y. O., Oriso S., Ota A., Otaki E., Saito Y., Sakai H., Sakamoto N., Sakamoto Y., Samejima Y., Sasagawa Y., Sasaguri H., Sasaki A., Sasaki T., Sato K., Sawano M., Seki S., Sekine Y., Seta Y., Sezaki K., Shibata N., Shiina Y., Shimono H., Shimoyama Y., Shindo T., Shinohara H., Shinohe R., Shinozuka T., Shirai T., Shiraiwa T., Shozawa Y., Suga T., Sugimoto C., Suzuki K., Suzuki S., Suzuki Y., Tada M., Taguchi A., Takagi T., Takagi Y., Takahashi K., Takahashi S., Takai H., Takanaka C., Take S., Takeda H., Takei K., Takenaka K., Tana T., Tanabe G., Taya K., Teragawa H., Tohyo S., Toru S., Tsuchiya Y., Tsuji T., Tsuzaki K., Uchiyama H., Ueda O., Ueyama Y., Wakaki N., Wakiyama T., Washizuka T., Watanabe M., Yamada T., Yamagishi T., Yamaguchi H., Yamamoto T., Yamaura M., Yamazoe M., Yasui K., Yokoyama Y., Yoshida K., Ching C. K., Foo C. G., Chow J. H., Chen D. D., Jaufeerally F. R., Lee Y. M., Lim G., Lim W. T., Thng S., Yap S. Y., Yeo C., Pak H. N., Kim J. -B., Kim J. H., Jang S. -W., Kim D. H., Ryu D. R., Park S. W., Kim D. -K., Choi D. J., Oh Y. S., Cho M. -C., Kim S. -H., Jeon H. -K., Shin D. -G., Park J. S., Park H. K., Han S. -J., Sung J. H., Cho J. -G., Nam G. -B., On Y. K., Lim H. E., Kwak J. J., Cha T. -J., Hong T. J., Park S. H., Yoon J. H., Kim N. -H., Kim K. -S., Jung B. C., Hwang G. -S., Kim C. -J., Kim D. B., Ahn J. J., An H. J., Bae H., Baek A. L., Chi W. J., Choi E. A., Choi E. H., Choi H. K., Choi H. S., Han S., Heo E. S., Her K. O., Hwang S. W., Jang E. M., Jang H. -S., Jang S., Jeon H. -G., Jeon S. R., Jeon Y. R., Jeong H. K., Jung I. -A., Kim H. J., Kim J. S., Kim J. A., Kim K. T., Kim M. S., Kim S. H., Kim Y. -I., Lee C. S., Lee E. H., Lee G. H., Lee H. Y., Lee H. -Y., Lee K. H., Lee K. R., Lee M. S., Lee M. -Y., Lee R. W., Lee S. E., Lee S. H., Lee S., Lee W. Y., Noh I. K., Park A. R., Park B. R., Park H. N., Park J. H., Park M., Park Y., Seo S. -Y., Shim J., Sim J. H., Sohn Y. M., Son W. S., Son Y. S., Song H. J., Wi H. K., Woo J. J., Ye S., Yim K. H., Yoo K. M., Yoon E. J., Yun S. Y., Chawanadelert S., Mongkolwongroj P., Kanokphatcharakun K., Cheewatanakornkul S., Laksomya T., Pattanaprichakul S., Chantrarat T., Rungaramsin S., Silaruks S., Wongcharoen W., Siriwattana K., Likittanasombat K., Katekangplu P., Boonyapisit W., Cholsaringkarl D., Chatlaong B., Chattranukulchai P., Santanakorn Y., Hutayanon P., Khunrong P., Bunyapipat T., Jai-Aue S., Kaewsuwanna P., Bamungpong P., Gunaparn S., Hongsuppinyo S., Inphontan R., Khattaroek R., Khunkong K., Kitmapawanont U., Kongsin C., Naratreekoon B., Ninwaranon S., Phangyota J., Phrommintikul A., Phunpinyosak P., Pongmorakot K., Poomiphol S., Pornnimitthum N., Pumprueg S., Ratchasikaew S., Sanit K., Sawanyawisuth K., Silaruks B., Sirichai R., Sriwichian A., Suebjaksing W., Sukklad P., Suttana T., Tangsirira A., Thangpet O., Tiyanon W., Vorasettakarnkij Y., Wisaratapong T., Wongtheptien W., Wutthimanop A., Yawila S., Altun A., Ozdogru I., Ozdemir K., Yilmaz O., Aydinlar A., Yilmaz M. B., Yeter E., Ongen Z., Cayli M., Pekdemir H., Ozdemir M., Sucu M., Sayin T., Demir M., Yorgun H., Ersanli M., Okuyan E., Aras D., Abdelrahman H., Aktas O., Alpay D., Aras F., Bireciklioglu M. F., Budeyri S., Buyukpapuc M., Caliskan S., Esen M., Felekoglu M. A., Genc D., Ikitimur B., Karaayvaz E. B., Karatas S. K., Okutucu S., Ozcelik E., Quisi A., Sag H., Sahiner L., Sayin B. Y., Seker T., Alkan D. U., Yildirim E., Yildirim R., Yilmaz F., Yuksekdag V., Vensentini N., Ingaramo A. C., Sambadaro G. A., Caputi V. F., Berman S. G., Dragotto P., Kleiban A. J., Centurion N., Giacomi G., Guerrero R. A. A., Conde D., Zapata G., Di Paola L. A., Ramos J. L., Dran R. D., Egido J., Fernandez A. A., Fosco M. J., Sassone S., Sinisi V. A., Cartasegna L. R., Berli M. A., Vilamajo O. A. G., Ferroni F., Alaguibe E. D., D'Amelio A. A., Arabetti C., Arias L., Belardi J. A., Bergesio L., Berli F., Berli M., Borchowiec S., Buzzetti C., Cabrini R., Campisi V., Cappi A. L., Carrizo R., Berra F. 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R., Cardona G. R., Cornejo M. R., Salinas A., Santana G., Perez P. S., Castaneda A. C. T., Cortes R. T., Lenz K., Drexel H., Foechterle J., Hagn C., Podczeck-Schweighofer A., Huber K., Winkler M., Schneeweiss B., Gegenhuber A., Lang W., Eichinger-Hasenauer S., Kaserer P., Sykora J., Rasch H., Pichler M., Schaflinger E., Strohmer B., Breier R., Ebner K. -M., Eischer L., Freihoff F., Lischka-Lindner A., Mark T., Mirtl A., Said A., Stocklocker C., Vogel B., Vonbank A., Wohrer C., Zanolin D., Paparella G., Vandergoten P., Parque J. -L., Capiau L., Vervoort G., Wollaert B., Desfontaines P., Mairesse G., Boussy T., Godart P., De Wolf A., Voet J., Heyse A., Hollanders G., Anne W., Vercammen J., Purnode P., Blankoff I., Faes D., Balthazar Y., Beutels M., Marechal P., Verstraete S., Xhaet O., Striekwold H., Thoeng J., Hermans K., Alzand B., Ascoop A. -K., Banaeian F., Barbuto A. -M., Billiaux A. C., Blockmans M., Bouvy C., Brike C., Capiau H., Casier T., Bolado A. C. Y., De Cleen D., De Coninck M., de Vos M., de Weerdt N., Delforge M., Delvigne M., Denie D., Derycker K., Deweerd E., Dormal F., Drieghe S., Everaert M., Eykerman T., Feys E., Ghekiere M., Gits F., Hellemans S., Helvasto L., Jacobs C., Lips S., Mestdagh I., Nimmegeers J., Piamonte V., Pollet P., Postolache A., Raepers M., Raymenants E., Richa J., Rombouts H., Salembier J., Scheurwegs C., Semeraro O., Simons N., Smessaert C., Smolders W., Stockman I., Tahon S., Thyssen V., Tincani G., Van Durme F., Van Lier D., Vandekerckhove H., Vandekerckhove Y., Vandenbroeck D., Vandorpe A., Vanhalst E., Vanhauwaert B., Vantomme C., Vergauwen L., Verloove H., Vydt T., Weyn T., Reichert P., Spacek R., Machova V., Zidkova E., Ludka O., Olsr J., Kotik L., Plocova K., Racz B., Ferkl R., Hubac J., Kotik I., Monhart Z., Burianova H., Jerabek O., Pisova J., Petrova I., Dedek V., Honkova M., Podrazil P., Spinar J., Vitovec J., Novak M., Lastuvka J., Durdil V., Antonova P., Bockova L., Bultas J., Chlumsky J., Dastychova L., Drasnar T., Honek J., Horejsi M., Hubacova V., Janska L., Kopeckova I., Kratochvilova R., Krcova E., Labrova R., Lindourkova A., Lipoldova J., Lubanda H., Ludkova A., Mahdalikova L., Majernikova M., Michalik D., Potuznik P., Prochazkova E., Sulc A., Sveceny J., Valtova M., Zidek M., Zika J., Nielsen H., Husted S., Hintze U., Rasmussen S., Bremmelgaard A., Markenvard J., Boerger J., Solgaard J., Simonsen P., Loekkegaard T., Bruun M., Mertz J., Dominguez H., Skagen K., Egstrup K., Ibsen H., Raymond I., Bang-Hansen T., Ellervik C., Eriksen E., Jensen L., Jensen M., Leth M., Nygaard A., Park J., Schou M., Therkelsen A., Tilma J., Vesterager K., Airaksinen J., Arola O., Koistinen J., Nappila H., Peltomaki K., Rasanen V., Vasankari T., Galinier M., Gottwalles Y., Paganelli F., Loiselet P., Muller J. -J., Koujan M. 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P., Fedorowsky A., Casassus F., Berneau J. -B., Chemin F., Falvo N., Perron J. -M., Poulard J. -E., Barreau A., Beltra C., Corrihons E., Decarsin N., Dubois B., Ducasse E., Giry X., Kemmel A., Ledure S., Lemaire N., Robin F., Rosolin N., Sanchez D., Suissa A., Koniger G., Purr J., Gerbaulet U., Kellner B. -T., Kopf A., Schafer T., Zauzig H., Riegel P., Hohensee H., Eissfeller E., Eder W., Rehling G., Glatzel D., Zutz S., Heinz G. -U., Menke H., Pustelnik A., Sandow P., Ludwig N., Wiswedel H., Wildenauer W., Axthelm C., Schwarz T., Babyesiza A., Stuchlik G., Zimny H. -H., Kropp M., Kahl F., Caspar A., Omankowsky S., Lassig T., Hartmann H. -J., Lehmann G., Bindig H. -W., Hergdt G., Reimer D., Hauk J., Dorsch W., Dshabrailov J., Michel H., Rapp K. -A., Vormann R., Mayer P., Horstmeier U., Eissing V., Hey H., Leuchtgens H., Lilienweiss V., Kolitsch K., Schubert C., Lauer H., Buchner T., Brauer G., Kamin S., Muller K., Abdel-Qader M., Baumbach S., Ebert H. -H., Schwencke C., Schellong S., Bernhardt P., Karolyi L., Sievers B., Haverkamp W., Salbach P., Rohnisch J. -U., Schoen S., Erdle W., Mueller T., Mueller H., Mitrovic V., Babjakova Z., Bergner K., Boehme S., Bonin K., Buckert D., Busch F., Dichristin U., Diez S., Fleck A., Flint K., Floegel H., Fritz C., Frommhold R., Gehre J., Geyer J., Grytzmann A., Hahn M., Helgert K., Hubert K., Kirchner-Volker K., Klein V., Kroll D., Krueger A., Lehmann R., Mann L., Maselli A., Menken G., Mikes K., Mortan H., Nasser N., Nicolaus D., Plauskat A., Pomper L., Quietzsch A., Ravenhorst C., Reichelt C., Reimer C., Schaefer B., Scharrer S., Schirmer K., Schmidt K., Schoene R., Schulze J., Schuppe M., Simon S., Sommer S., Spranger K., Talkenberger A., Tauber K., Tetlak A., Toennishoff T., Voelkel-Babyesiza R., Voigts B., Weiser U., Wesendorf S., Wildenauer S., Wolf T., Wurziger J., Zak J., Zauzig H. -D., Ziefle S., Zincke S., Vangel S., Szalai G., Merkely B., Kancz S., Boda Z., Nagy A., Laszlo Z., Matoltsy A., Gaszner B., Polgar P., Habon T., Noori E., Juhasz G., Kanakaridisz N., Szentpeteri I., Juhasz F., Vertes A., Papp A., May Z., Ferenczi J., Egyutt M., Kis E., Engelthaler G., Szantai G., Fulop E., Gombos P., Gulyas D., Jen P., Kiralyhazine Gyorke E., Kovacs M., Kovacsne Levang S., Marianna S., Radics Z., Sydo N., Szalo R., Szilagyi A., Sztanyik F., Vandrus B., Tiraferri E., Santoro R., Testa S., Di Minno G., Moia M., Caimi T. 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G., Severi S., Capucci A., Lodigiani C., Salomone E., Serviddio G., Tondo C., Golino P., Mazzone C., Iacopino S., Pengo V., Galvani M., Moretti L., Ambrosino P., Banfi E., Biagioli V., Bianchi A., Boggian G., Breschi M., Brusorio S., Calcagnoli F., Campagna G., Carpenedo M., Ciabatta C., Ciliberti G., Cimmino G., D'Arienzo C., Di Gennaro L., Fedele M., Ferrini P. M., Granzow K., Guazzaloca G., Guerra F., Lo Buglio A., Longo S., Macellari F., Mesolella E., Mollica Poeta E., Occhilupo P., Oriana V., Rangel G., Salomone L., Scaccianoce A., Scarone C., Segreti L., Sottilota G., Villani R., Zecca C., Ruiter J. H., Klomps H., Bongaerts M., Pieterse M. G. C., Guldener C., Herrman J. -P., Lochorn G., Lucassen A., Adriaansen H., The S. H. K., Nierop P. R., Hoogslag P. A. M., Hermans W., Groenemeijer B. E., Terpstra W., Buiks C., Boersma L. V. A., Boersma-Slootweg M., Bosman F., Bosschaert M., Bruin S., Danse I., De Graaf J., de Graauw J., Debordes M., Dols S., Geerlings F., Gorrebeeck K., Jerzewski A., Jetten W., Kelderman M., Kloosterman T., Koomen E. M., Krikken J., Melman P., Mulder R., Pronk A., Stallinga-de Vos A., te Kaat J., Tonino P., Uppelschoten B., van de Loo R., van der Kley T., van Leeuwen G., van Putten J. J., Westerman L., Berge E., Sirnes P. A., Gjertsen E., Hole T., Erga K., Hallaraker A., Skjelvan G., Ostrem A., Ghezai B., Svilaas A., Christersson P., Oien T., Hoegh Henrichsen S., Berg-Johansen J., Otterstad J. E., Antonsen H., Ausen K., Claussen H., Dominguez I., Jekthammer A., Lensebraaten A. B., Nilsen V., O'Donovan M., Ringdalen K., Strand S., Korzeniak R., Gieroba A., Biedrzycka M., Ogorek M., Wozakowska-Kaplon B., Loboz-Grudzien K., Kosior J., Supinski W., Kuzniar J., Zaluska R., Hiczkiewicz J., Swiatkowska-Byczynska L., Kucharski L., Gruchala M., Minc P., Olszewski M., Kania G., Krzciuk M., Lajkowski Z., Ostrowska-Pomian B., Lewczuk J., Zinka E., Karczmarczyk A., Chmielnicka-Pruszczynska M., Trusz-Gluza M., Opolski G., Bronisz M., Glanowska G., Ruszkowski P., Jaworska K., Sciborski R., Okopien B., Kukla P., Wozniak-Skowerska I., Galbas K., Cymerman K., Jurowiecki J., Miekus P., Myszka W., Mazur S., Lysek R., Baszak J., Rusicka-Piekarz T., Raczak G., Domanska E., Nessler J., Lesnik J., Ambicka M., Andrzejewski D., Araminowicz J., Barszcz A., Bartkowiak R., Bartnik J., Basiak M., Bekieszczuk E., Bernat L., Biedrzycki L., Biernacka A., Blaszczyk D., Broton E., Brzozowski W., Brzustowska M., Bzymek R., Chmielowski A., Chojnowski P., Cichomski R., Cieslak K., Cieszynska A., Curyllo B., Czamara M., Danilowicz-Szymanowicz L., Dolecka B., Drelich L., Dudzik-Richter B., Dybala T., Dziuba M., Faron W., Figura-Chmielewska M., Frankiewicz A., Gadzinski W., Gasior E., Gosciniecka B., Gutknecht P., Guziewicz M., Jackun-Podlesna A., Jaguszewska G., Jankielewicz J., Jaremczuk-Kaczmarczyk A., Jargiello-Baszak M., Jarzebowski A., Jaskulska-Niedziela E., Jaworska-Drozdowska M., Kabat J., Kaczmarzyk-Radka A., Kalin K., Kaliszczak R., Kiliszek M., Klata M., Kluczewski M., Kobielusz-Gembala I., Kochanska E., Kociolek D., Kolodzinska A., Komlo A., Konopka A., Korczowska E., Kowal E., Kowalczyk H. K., Kremis E., Kruczyk D., Krzesiak-Lodyga A., Krzyzanowski M., Kurdzielewicz W., Kustrzycka-Kratochwil D., Lesniewska-Krynska D., Leszczynski J., Lewicka E., Lichota E., Lip K., Loboz-Rudnicka M., Luka J., Lysek-Jozefowicz A., Machnikowska M., Majewska K., Mariankowski R., Markiewicz A., Mazur M., Metzgier-Gumiela A., Miedlar E., Mielcarek M., Neubauer-Geryk J., Niedek J., Niemirycz-Makurat A., Nowak A., Nowak S., Opielowska-Nowak B., Ozgowicz M., Pawelska-Buczen A., Pawlik-Rak E., Piotrowicz R., Ptaszynski P., Raczynska A., Rogowski W., Romanek J., Romaszkiewicz R., Rostoff P., Roszczyk N., Rozewska-Furmanek D., Rychta J., Rzyczkowska B., Sidor A., Skalska J., Smichura M., Splawski M., Staneta P., Staniszewska E., Starak-Marciniak J., Stopyra-Poczatek M., Sukiennik-Kujawa M., Szafranski J., Szalecki P., Szczepanska A., Szkrobka W., Szuchnik E., Szulowska A., Szumczyk-Muszytowska G., Szwoch M., Traczyk T., Troszczynska M., Trzcinski G., Tybura S., Walasik P., Wegrzynowska M., Wesolowska K., Wieczorek W., Wierzbicka A., Wilczewski P., Wilgat-Szecowka M., Wojewoda P., Wojnowski L., Wrobel M., Zakutynska-Kowalczyk K., Zyczynska-Szmon M., Eltishcheva V., Libis R., Tereshchenko S., Popov S., Kamalov G., Belenky D., Zateyshchikova A., Kropacheva E., Kolesnikova A., Nikolaev K., Egorova L., Khokhlov A., Yakupov E., Poltavskaya M., Zateyshchikov D., Drapkina O., Vishnevsky A., Barbarash O., Miller O., Aleksandrova E., Chizhov P., Sergeev M., Shutemova E., Mazur E., Zrazhevskiy K., Novikova T., Kostenko V., Moiseeva Y., Polkanova E., Sobolev K., Rossovskaya M., Zubeeva G., Shapovalova Y., Nagibovich O., Edin A., Agakhanyan A., Batalov R., Belenkova Y., Bitakova F., Chugunnaya S., Dumikyan A., Erofeeva S., Gorbunova E., Gorshkova T., Gubanov A., Gurmach M., Ivanova Y., Kolesova T., Konyushenko D., Korneeva O., Kropova O., Kuchuk P., Kungurtseva O., Kupriyanova T., Kurylo B., Kuvanova M., Lebedeva O., Lileeva E., Machilskaya O., Medvedeva T., Monako G., Motylev I., Nagibovich G., Novikova E., Orlov Y., Osmolovskaya Y., Ovsannikova A., Platonov D., Rachkova S., Sinitsina O., Speshilova S., Suslova O., Ushakov A., Volodicheva O., Zemlianskaia O., Zhirov I., Zhuravleva E., Zotova I., Garcia P. A., Fernandez M. F. L., Tercedor L., Iparraguirre S. T., Monserrat P. T., Contreras E. M., Rafecas J. I., Carrasco J. M., Pavia P. G., Pajuelo C. G., Serrano C. M., Alonso L. F. I., Ruiz A. G., Klein J. M., Juanatey J. R. G., Esquivias G. B., Collado I. M., Piquero H. P., Cuixart C. B., Morato M. R., Llibre J. B. I., Vicente C. C., Gutierrez M. V., Gonzalo F. E., Fernandez C. A. A., Plana N. D. V., Montserrat E. E., Alia J. J. M., Oliva M. A. M., Sanmartin J. I., Gonzalez M. J., Alvarez M. R., Melenchon J. H., Vera T. R., Soriano F. R., Riesco L. G., Macian M. D. M., Granado J. Q., Navarro M. J., Sales J. C., Perez J. V. V., Caamano M. V., Torres M. F. A., Gomez G. M., Romo A. I., Diaz M. A. P., Alonso C., Alvarez D., Alvarez M., Amaro M., Andere N., Villar J. A., Ochoa R. A., Austria A., Barbeira S., Feu E. B., Bartes A., Munoz V. B., Jimenez F. J. B., Tijuan A. B., Ramirez J. C., Ramos M. C., Martinez E. C., Moreno M. C., Corchado G. C., Gil M. C., Orive M. C., Fernandez D. C., del Misterio M. C., Alsina R. C., Cabrera A. C., de Faria J. C. P. P., Costas S., Marco M. I. C., Dachs M., Lopez C. M. D., Borras A. D., Madariaga A. E., Espallargas A., Fernandez M., Escobar E. F., Mas E. F., Ferrer A., Fosch J., Bermudez M. G., Millan V. G., Saenz M. G., Garcia C. G., Gomez C., Perez Y. G., Segovia A. G., Gonzalez P., Grigorian L., Molina A. G., del Val M. C. G., Maeso B. H., Rodriguez E. H., Garcia A. I., Fernandez M. J. J., Besa B. J., Salvadores P. J., Bouzamayor M. B. L., Lasuncion I., Gort L. E. L., Molina M. L., Lopez M., Rey A. M., Guerra J. M., Marcus S., Vila A. M., Mena M. M., Mazon P., Zurita F. M., Millan G., Molina M., Alia P. M., Montes D., Gonzalez M. M., Munoz R. B. M., Palma A. N., Figueroa H. N. O., Ortega V. M., Cortes C. O., Tomera D. O., Merchan N. P., Ibar I. P., Garcia E. P., Armayor M. P., Carasa M. P., Prieto I., Quintern V., Renom R., Diaz L. M. R., Rios V., Sola L. R., Rivera R., Robiro X. R., Roca M., Saumell C. R., Rodrigo C., Rodriguez E., Garcia M. R., Jimenez S. S., Calderon P. S., Mendez L. S., Parra S. S., Santolaya C., Sanz M. R. S., Blanco A. S., Serralvo E., Sierra N., Valero C. S., Lopez J. S., Fontanillas M. T., Riera M. T., Tobajas G., Torres C., Marques J. T., Pastor M. U., Wirdby A., Linden J., Henriksson K., Elmersson M., Egilsson A., Borjesson U., Svard G., Liu B., Lindh A., Olsson L. -B., Gustavsson M., Andersson L., Benson L., Bothin C., Hajimirsadeghi A., Kadir K., Ericsson M., Ohlsson A., Lindvall H., Svensson P., Thorne K., Handel H., Platonov P., Eriksson B., Timberg I., Romberg K., Crisby M., Karlsson J. -E., Jensen S. A., Andersson A., Malmqvist L., Martinsson B., Bernsten F., Engdahl J., Thulin J., Hot-Bjelac A., Stalby P., Aaroe H., Ahbeck E., Ahlmark H., Al-Khalili F., Bonkowski G., Dzeletovic S., Ekstrand A. -B., Eriksson G. -B., Floren K., Grassjo C., Hahn S., Jaensson P., Jansson B., Jansson J. -H., Kangert R. -M., Koch A., Kusiak D., Lettenstrom A., Lindberg A., Lindholm C. -J., Mannermyr A., Mansson K., Millborg M., Nilsson C., Ohlin A. -M., Olofsson A., Osberg A., Pedersen A., Risbecker K., Rosenberg K., Samuelsson J., Shayesteh M., Skoglund K., Stjernberg M., Thorsen C., Beer J. H., Debrunner J., Amstutz D., Bruegger J., Elise G., Grau A., Guinand A., Henriette I., Saga E., Winnik S., Rudyk I., Tseluyko V., Karpenko O., Zhurba S., Kraiz I., Kupnovytska I., Serediuk N., Mostovoy Y., Ushakov O., Koval O., Kovalskyi I., Svyshchenko Y., Sychov O., Stanislavchuk M., Kraydashenko O., Yagensky A., Tykhonova S., Fushtey I., Belegai R., Berko G., Burdeuna L., Chabanna O., Daniuk I., Ivanov A., Kamenska E., Kaplan P., Khyzhnyak O., Kizim S., Matova O., Medentseva O., Mochonyi V., Mospan M., Nemtsova V., Ovdiienko T., Palamarchuk O., Pavelko M., Petrovskyy R., Plevak D., Proshak O., Pyvovar S., Rasputina L., Romanenko O., Romanova O., Sapatyi A., Shumakov O., Stets R., Todoriuk L., Varenov V., Chauhan N., Goodwin D., Saunders P., Evans R., Leese J., Jhittay P. S., Ross A., Kainth M. S., Pickavance G., McDonnell J., Williams A., Gooding T., Wagner H., Suryani S., Singal A., Sircar S., Bilas R., Hutchinson P., Wakeman A., Stokes M., Paul N., Aziz M., Ramesh C., Wilson P., Franklin S., Fairhead S., Thompson J., St Joseph V., Taylor G., Tragen D., Seamark D., Paul C., Richardson M., Jefferies A., Sharp H., Jones H., Giles C., Page M., Oginni O., Aldegather J., Wetherwell S., Lumb W., Evans P., Scouller F., Macey N., Stipp Y., West R., Thurston S., Wadeson P., Matthews J., Pandya P., Gallagher A., Railton T., Sinha B., Russell D., Davies J. A., Ainsworth P., Jones C. P., Weeks P., Eden J., Kernick D., Murdoch W., Lumley L., Patel R. P., Wong S. W., Saigol M., Ladha K., Douglas K., Cumberlidge D. F., Bradshaw C., Van Zon G., Jones K. P., Thomas M. J., Watson E., Sarai B., Ahmad N., Willcock W., Cairns J., Sathananthan S., de Kare-Silver N., Gilliland A., Strieder E., Howitt A., Vishwanathan B., Bird N., Gray D., Clark M., Bisatt J., Litchfield J., Fisher E., Fooks T., Kelsall A. R., Alborough E., Wakeling J., Parfitt M., Milne K., Rogers S., Priyadharshan R., Oliver J. L., Davies E., Abushal S., Jacobs M., Hutton C., Walls N. I., Thompson R., Chigbo C., Zaidi S. M. A., Howard M., Butter K. C., Barrow S., Little H., Haq I. U., Gibbons L., Glencross S., McLeod A. J., Poland K., Mulholland C., Warke A., Conn P., Burns G., Smith R. N., Lowe S., Kamath R., Dau H. S., Webster J., Hodgins I., Vercoe S., Roome P. C., Pinnock H., Patel J. R. A., Ali A., Hart N., Davies R., Stuart E., Neden C. A., Danielsen M., Heath R., Sharma P., Galloway S., Hawkins C., Oliver R., Aylward M., Mannion S., Braddick M., Edwards D., Rothwell A. C., Sabir A., Choudhary F., Khalaque S., Wilson A., Peters S., Coulson W., Roberts N., Heer A., Coates S., Ward B., Jackson D., Walton S., Shepherd D., Sterry M., Wong T., Boon M., Bunney R., Haria-Shah R., Baron R. T., Davies S., Schatzberger T., Hargreaves N., Stephenson T., Choi H., Batson R., Lucraft L., Myhill T., Estifano S., Geatch D., Wilkinson J., Veale R., Forshaw K., Davies T., Zaman K., Vinson P., Liley C., Bandrapalli M., McGinty P., Wastling R., McEleny P., Beattie A., Cooke P., Wong M., Gunasegaram J., Pugsley M., Ahmad S., A'Court C., Ayers J., Bennett J., Cartwright S., Dobson S., Dooldeniya C., Flynn A., Fox R., Goram J., Halpin A., Hay A., Jacobs P., Jeffers L., Lomax L., Munro I., Muvva R., Nadaph M., Powell K., Randfield S., Redpath D., Reed R., Rickenbach M., Rogers G., Saunders P. B., Seamark C., Shewring J., Simmons P., Simper H., Stoddart H., Sword A., Thomas N., Thomson A., Blenkhorn A., Singh B., Van Gaal W., Abhayaratna W., Lehman R., Roberts-Thomson P., Kilian J., Coulshed D., Catanchin A., Colquhoun D., Kiat H., Eccleston D., French J., Zimmett L., Ayres B., Phan T., Blombery P., Crimmins D., O'Donnell D., Choi A., Astridge P., Arstall M., Jepson N., Binnekamp M., Lee A., Rogers J., Starmer G., Carroll P., Faunt J., Aggarwala A., Barry L., Batta C., Beveridge R., Black A., Bonner M., Boys J., Buckley E., Campo M., Carlton L., Connelly A., Conway B., Cresp D., Dimitri H., Dixon S., Dolman M., Duroux M., Eskandari M., Eslick R., Ferreira-Jardim A., Fetahovic T., Fitzpatrick D., Geraghty R., Gibbs J., Grabek T., Modi M. H., Hayes K., Hegde M. P., Hesketh L., Hoffmann B., Johnson K., Juergens C., Kassam I., Lawlor V., Lehman M., Lehman S., Leung D., Mackay S., MacKenzie M., McCarthy C., McIntosh C., McKeon L., Morrison H., Mussap C., Myers J. -D., Nagalingam V., Oldfield G., O'May V., Palmer J., Parsons L., Patching K., Patching T., Paul V., Plotz M., Preston S., Rashad H., Ratcliffe M., Raynes S., Rose J., Sanders L., Seremetkoska M., Setio H., Shone S., Shrestha P., Singh C., Singleton C., Stoyanov N., Sutcliffe S., Swaraj K., Tarrant J., Thompson S., Tsay I. M., Vorster M., Waldman A., Wallis L., Wilford E., Wong K., Luton R., Gupta M., Pandey A. S., Cheung S., Leader R., Beaudry P., Ayala-Paredes F., Berlingieri J., Heath J., Poirier G., Du Preez M., Nadeau R., Dresser G., Dhillon R., Hruczkowski T., Schweitzer B., Coutu B., Angaran P., MacDonald P., Vizel S., Fikry S., Parkash R., Lavoie A., Cha J., Ramjattan B., Bonet J., Ahmad K., Aro L., Aves T., Beaudry K., Bergeron C., Bigcanoe J., Bignell N., Breakwell L., Burke E., Carroll L., Clarke B., Cleveland T., Daheb S., Dehghani P., Denis I., Djaidani Z., Dorian P., Douglass S., Dunnigan J., Ewert A., Farquhar D., Fearon A., Ferleyko L., Fournier D., Fox B., Grenier M. -C., Gulliver W., Haveman K., Hines C., Hines K., Jackson A. M., Jean C., Jethoo G., Kahlon R., Kelly S., Kim R., Korley V., Kornder J., Kwan L., Largy J., Lewis C., Lewis S., Mangat I., Moor R., Navratil J., Neas I., Otis J., Otis R., Pandey M., Petrie F., Pinter A., Raines M., Roberts P., Robinson M., Sas G., Schulman S., Snell L., Spearson S., Stevenson J., Trahey T., Wong S., Wright D., El-Aziz A. A., Seif S. K. A., El Din M. G., El Etriby S., Elbahry A., El-Etreby A., Elkhadem M., Katta A., Khairy T., Mowafy A., Nawar M., Ohanissian A., Reda A., Reda M., Salem H., Sami N., Samir S., Setiha M., Sobhy M., Soliman A., Taha N., Tawfik M., Zaatout E., Kettles D., Bayat J., Siebert H., Horak A., Kelfkens Y., Garda R., Pillay T., Guerra M., van Zyl L., Theron H., Murray A., Louw R., Greyling D., Mntla P., Ueckermann V., Loghdey R., Ismail S., Ahmed F., Engelbrecht J., Ramdass A., Maharajh S., Oosthuysen W., Angel G., Bester C., Booysen M., Boshoff C., Cannon C., Cassimjee S., Chami C., Conway G., Davids A., de Meyer L., Du Plessis G., Ellis T., Henley L., Karsten M., Loyd E., Marks J., Mavhusa L., Mostert M., Page A., Rikhotso L., Salie M., Sasto J., Shaik F., Skein A., Smith L., Tarr G., Tau T., van Zyl F., Yousef G., Agrawal A., Nathani M., Ibrahim M., Esheiba E. M., Singh R., Naguib A., Abu-Mahfouz M., Al Omairi M., Al Naeemi A., Maruthanayagam R., Bazargani N., Wassef A., Gupta R., Khan M., Subbaraman B., Abdul A., Al Mulla A., El Bardisy S., Haridas P., Jadhav S., Magdaluyo K., Makdad M., Maqsood I., Mohamed R., Sharma N., Sharma R., Thanzeel M., Canosa R., Rama P., Blumberg E., Garcia J., Mullen P., Wilson V., Quick A., Ferrick K., Kutayli W. M., Cox M., Franco M., Falkowski S., Mendelson R., Williams M., Miller S., Beach S., Alfieri A., Gutowski T., Haque I., Reddy R., Ahmed W., Delafontaine P., Diercks D., Theodoro D., Remmel K., Alberts M., Ison R., Noveck H., Duffy P., Pitta S., Nishijima D., Treasure C., Asafu-Adjaye N., Ball K., Bartlett M., Bentley M., Bowers S., Brown A., Browne A., Cameron-Watts J., Canova M., Cassidy D., Cervellione K., Congal S., DePauw J., Dickerson A., Eley M., Evans L., Felpel S., Ferdinand K., Fielder D., Gentry P., Haideri A., Hakimi F., Harbour T., Hartranft E., Hawkins B., Headlee M., Henson L., Herrick C., Hicks T., Jasinski S., Jones A., Jones L., Jones P., Karl S., Keeling M., Kerr J., Knowles P., Langdon J., Lay M., Lee J. A., Lincoln T., Malone E., Merliss A., Merritt D., Minardo J., Mooso B., Orosco C., Palumbo V., Parker M., Parrott T., Paserchia S., Pearl G., Peterson J., Pickelsimer N., Purcell T., Raynor J., Raziano S., Richard C., Richardson T., Robertson C., Sage A., Sanghera T., Shaw P., Shoemaker J., Smith K., Stephanie B., Thatcher A., Theobald H., Thompson N., Treasure L., Tripti T., Verdi C., Worthy V., Jerjes-Sanchez, C, Corbalan, R, Barretto, A, Luciardi, H, Allu, J, Illingworth, L, Pieper, K, Kayani, G, Fitzmaurice, D, Goto, S, Hacke, W, Mantovani, L, Turpie, A, Gersh, B, Gibbs, H, Brodmann, M, Cools, F, Connolly, S, Spyropoulos, A, Eikelboom, J, Hu, D, Jansky, P, Nielsen, J, Ragy, H, Raatikainen, P, Le Heuzey, J, Darius, H, Keltai, M, Kakkar, S, Sawhney, J, Agnelli, G, Ambrosio, G, Koretsune, Y, Diaz, C, ten Cate, H, Atar, D, Stepinska, J, Panchenko, E, Lim, T, Jacobson, B, Oh, S, Vinolas, X, Rosenqvist, M, Steffel, J, Angchaisuksiri, P, Parkhomenko, A, Al Mahmeed, W, Chen, K, Zhao, Y, Zhang, H, Chen, J, Cao, S, Wang, D, Yang, Y, Li, W, Yin, Y, Tao, G, Yang, P, Chen, Y, He, S, Wang, Y, Fu, G, Li, X, Wu, T, Cheng, X, Yan, X, Zhao, R, Chen, M, Xiong, L, Chen, P, Jiao, Y, Guo, Y, Xue, L, Wang, F, Li, H, Yang, Z, Bai, C, Chen, X, Feng, S, Fu, Q, Gao, X, Guo, W, He, R, He, X, Hu, X, Huang, X, Li, B, Li, J, Li, L, Li, Y, Liu, T, Liu, W, Liu, Y, Lu, Z, Luo, X, Ma, T, Peng, J, Sheng, X, Shi, X, Sun, Y, Tian, G, Wang, K, Wang, L, Wu, R, Xie, Q, Xu, R, Yang, J, Yang, L, Yang, Q, Ye, Y, Yu, H, Yu, J, Yu, T, Zhai, H, Zhan, Q, Zhang, G, Zhang, Q, Zhang, R, Zhang, Y, Zheng, W, Zhou, B, Zhou, Z, Zhu, X, Jadhav, P, Durgaprasad, R, Ravi Shankar, A, Rajput, R, Bhargava, K, Sarma, R, Srinivas, A, Roy, D, Nagamalesh, U, Chopda, M, Kishore, R, Kulkarni, G, Chandwani, P, Pothiwala, R, Padinhare Purayil, M, Shah, S, Chawla, K, Kothiwale, V, Raghuraman, B, Vijayaraghavan, G, Vijan, V, Bantwal, G, Bisne, V, Khan, A, Gupta, J, Kumar, S, Jain, D, Abraham, S, Adak, D, Barai, A, Begum, H, Bhattacharjee, P, Dargude, M, Davies, D, Deshpande, B, Dhakrao, P, Dhyani, V, Duhan, S, Earath, M, Ganatra, A, Giradkar, S, Jain, V, Karthikeyan, R, Kasala, L, Kaur, S, Krishnappa, S, Lawande, A, Lokesh, B, Madarkar, N, Meena, R, More, P, Naik, D, Prashanth, K, Rao, M, Rao, N, Sadhu, N, Shah, D, Sharma, M, Shiva, P, Singhal, S, Suresh, S, Vanajakshamma, V, Panse, S, Kanamori, S, Yamamoto, K, Kumagai, K, Katsuda, Y, Sadamatsu, K, Toyota, F, Mizuno, Y, Misumi, I, Noguchi, H, Ando, S, Suetsugu, T, Minamoto, M, Oda, H, Shiraishi, K, Adachi, S, Chiba, K, Norita, H, Tsuruta, M, Koyanagi, T, Ando, H, Higashi, T, Okada, K, Azakami, S, Komaki, S, Kumeda, K, Murayama, T, Matsumura, J, Oba, Y, Sonoda, R, Goto, K, Minoda, K, Haraguchi, Y, Suefuji, H, Miyagi, H, Kato, H, Nakamura, T, Nandate, H, Zaitsu, R, Fujiura, Y, Yoshimura, A, Numata, H, Ogawa, J, Tatematsu, H, Kamogawa, Y, Murakami, K, Wakasa, Y, Yamasawa, M, Maekawa, H, Abe, S, Kihara, H, Tsunoda, S, Saito, K, Fudo, T, Obunai, K, Tachibana, H, Oba, I, Kuwahata, T, Higa, S, Gushiken, M, Eto, T, Yoshida, H, Ikeda, D, Ishizawa, M, Nakatsuka, M, Murata, K, Ogurusu, C, Shimoyama, M, Akutsu, M, Takamura, I, Hoshino, F, Yokota, N, Iwao, T, Tsuchida, K, Takeuchi, M, Hatori, Y, Kitami, Y, Nakamura, Y, Oyama, R, Ageta, M, Go, Y, Mishima, K, Unoki, T, Morii, S, Shiga, Y, Sumi, H, Nagatomo, T, Sanno, K, Fujisawa, K, Atsuchi, Y, Nagoshi, T, Seto, T, Tabuchi, T, Kameko, M, Nii, K, Oshiro, K, Takezawa, H, Nagano, S, Miyamoto, N, Iwaki, M, Fujii, M, Okawa, M, Abe, M, Saito, T, Mito, T, Nagao, K, Minami, J, Mita, T, Sakuma, I, Taguchi, T, Marusaki, S, Doi, H, Tanaka, M, Fujito, T, Matsuta, M, Kusumoto, T, Kakinoki, S, Ashida, K, Yoshizawa, N, Agata, J, Arasaki, O, Manita, M, Ikemura, M, Fukuoka, S, Murakami, H, Matsukawa, S, Hata, Y, Taniguchi, T, Ko, T, Kubo, H, Imamaki, M, Akiyama, M, Inagaki, M, Odakura, H, Ueda, T, Katsube, Y, Nakata, A, Watanabe, H, Techigawara, M, Igarashi, M, Taga, K, Kimura, T, Tomimoto, S, Shibuya, M, Nakano, M, Ito, K, Seo, T, Hiramitsu, S, Hosokawa, H, Hoshiai, M, Hibino, M, Miyagawa, K, Horie, H, Sugishita, N, Soma, A, Neya, K, Yoshida, T, Mizuguchi, M, Ishiguro, M, Minagawa, T, Wada, M, Mukawa, H, Okuda, F, Nagasaka, S, Abe, Y, Adachi, T, Akahane, K, Amano, T, Aoki, K, Aoyama, T, Arai, H, Arima, S, Arino, T, Asano, H, Asano, T, Azuma, J, Baba, T, Betsuyaku, T, Chibana, H, Date, H, Doiuchi, J, Emura, Y, Endo, M, Fujii, Y, Fujiki, R, Fujisawa, A, Fujisawa, Y, Fukuda, T, Fukui, T, Furukawa, N, Furukawa, T, Furumoto, W, Goto, T, Hamaoka, M, Hanazono, N, Hasegawa, K, Hatsuno, T, Hayashi, Y, Higuchi, K, Hirasawa, K, Hirayama, H, Hirose, M, Hirota, S, Honda, M, Ido, T, Iiji, O, Ikeda, H, Ikeda, K, Ikeoka, K, Imaizumi, M, Inaba, H, Inoue, T, Iseki, F, Ishihara, A, Ishioka, N, Ito, N, Iwase, T, Kakuda, H, Kamata, J, Kanai, H, Kanda, H, Kaneko, M, Kano, H, Kasai, T, Kato, T, Kato, Y, Kawada, Y, Kawai, K, Kawakami, K, Kawakami, S, Kawamoto, T, Kawano, S, Kim, J, Kira, T, Kitazawa, H, Kitazumi, H, Kito, T, Kobayashi, T, Koeda, T, Kojima, J, Komatsu, H, Komatsu, I, Koshibu, Y, Kotani, T, Kozuka, T, Kumai, Y, Kumazaki, T, Maeda, I, Maeda, K, Maruyama, Y, Matsui, S, Matsushita, K, Matsuura, Y, Mineoi, K, Mitsuhashi, H, Miura, N, Miyaguchi, S, Miyajima, S, Miyamoto, H, Miyashita, A, Miyata, S, Mizuguchi, I, Mizuno, A, Mori, T, Moriai, O, Morishita, K, Murai, O, Nagai, S, Nagata, E, Nagata, H, Nakagomi, A, Nakahara, S, Nakamura, M, Nakamura, R, Nakanishi, N, Nakayama, T, Nakazato, R, Nanke, T, Nariyama, J, Niijima, Y, Niinuma, H, Nishida, Y, Nishihata, Y, Nishino, K, Nishioka, H, Nishizawa, K, Niwa, I, Nomura, K, Nomura, S, Nozoe, M, Ogawa, T, Ohara, N, Okada, M, Okamoto, K, Okita, H, Okuyama, M, Ono, H, Ono, T, Pearce, Y, Oriso, S, Ota, A, Otaki, E, Saito, Y, Sakai, H, Sakamoto, N, Sakamoto, Y, Samejima, Y, Sasagawa, Y, Sasaguri, H, Sasaki, A, Sasaki, T, Sato, K, Sawano, M, Seki, S, Sekine, Y, Seta, Y, Sezaki, K, Shibata, N, Shiina, Y, Shimono, H, Shimoyama, Y, Shindo, T, Shinohara, H, Shinohe, R, Shinozuka, T, Shirai, T, Shiraiwa, T, Shozawa, Y, Suga, T, Sugimoto, C, Suzuki, K, Suzuki, S, Suzuki, Y, Tada, M, Taguchi, A, Takagi, T, Takagi, Y, Takahashi, K, Takahashi, S, Takai, H, Takanaka, C, Take, S, Takeda, H, Takei, K, Takenaka, K, Tana, T, Tanabe, G, Taya, K, Teragawa, H, Tohyo, S, Toru, S, Tsuchiya, Y, Tsuji, T, Tsuzaki, K, Uchiyama, H, Ueda, O, Ueyama, Y, Wakaki, N, Wakiyama, T, Washizuka, T, Watanabe, M, Yamada, T, Yamagishi, T, Yamaguchi, H, Yamamoto, T, Yamaura, M, Yamazoe, M, Yasui, K, Yokoyama, Y, Yoshida, K, Ching, C, Foo, C, Chow, J, Chen, D, Jaufeerally, F, Lee, Y, Lim, G, Lim, W, Thng, S, Yap, S, Yeo, C, Pak, H, Jang, S, Kim, D, Ryu, D, Park, S, Choi, D, Oh, Y, Cho, M, Kim, S, Jeon, H, Shin, D, Park, J, Park, H, Han, S, Sung, J, Cho, J, Nam, G, On, Y, Lim, H, Kwak, J, Cha, T, Hong, T, Yoon, J, Kim, N, Kim, K, Jung, B, Hwang, G, Kim, C, Ahn, J, An, H, Bae, H, Baek, A, Chi, W, Choi, E, Choi, H, Heo, E, Her, K, Hwang, S, Jang, E, Jang, H, Jeon, S, Jeon, Y, Jeong, H, Jung, I, Kim, H, Kim, M, Kim, Y, Lee, C, Lee, E, Lee, G, Lee, H, Lee, K, Lee, M, Lee, R, Lee, S, Lee, W, Noh, I, Park, A, Park, B, Park, M, Park, Y, Seo, S, Shim, J, Sim, J, Sohn, Y, Son, W, Son, Y, Song, H, Wi, H, Woo, J, Ye, S, Yim, K, Yoo, K, Yoon, E, Yun, S, Chawanadelert, S, Mongkolwongroj, P, Kanokphatcharakun, K, Cheewatanakornkul, S, Laksomya, T, Pattanaprichakul, S, Chantrarat, T, Rungaramsin, S, Silaruks, S, Wongcharoen, W, Siriwattana, K, Likittanasombat, K, Katekangplu, P, Boonyapisit, W, Cholsaringkarl, D, Chatlaong, B, Chattranukulchai, P, Santanakorn, Y, Hutayanon, P, Khunrong, P, Bunyapipat, T, Jai-Aue, S, Kaewsuwanna, P, Bamungpong, P, Gunaparn, S, Hongsuppinyo, S, Inphontan, R, Khattaroek, R, Khunkong, K, Kitmapawanont, U, Kongsin, C, Naratreekoon, B, Ninwaranon, S, Phangyota, J, Phrommintikul, A, Phunpinyosak, P, Pongmorakot, K, Poomiphol, S, Pornnimitthum, N, Pumprueg, S, Ratchasikaew, S, Sanit, K, Sawanyawisuth, K, Silaruks, B, Sirichai, R, Sriwichian, A, Suebjaksing, W, Sukklad, P, Suttana, T, Tangsirira, A, Thangpet, O, Tiyanon, W, Vorasettakarnkij, Y, Wisaratapong, T, Wongtheptien, W, Wutthimanop, A, Yawila, S, Altun, A, Ozdogru, I, Ozdemir, K, Yilmaz, O, Aydinlar, A, Yilmaz, M, Yeter, E, Ongen, Z, Cayli, M, Pekdemir, H, Ozdemir, M, Sucu, M, Sayin, T, Demir, M, Yorgun, H, Ersanli, M, Okuyan, E, Aras, D, Abdelrahman, H, Aktas, O, Alpay, D, Aras, F, Bireciklioglu, M, Budeyri, S, Buyukpapuc, M, Caliskan, S, Esen, M, Felekoglu, M, Genc, D, Ikitimur, B, Karaayvaz, E, Karatas, S, Okutucu, S, Ozcelik, E, Quisi, A, Sag, H, Sahiner, L, Sayin, B, Seker, T, Alkan, D, Yildirim, E, Yildirim, R, Yilmaz, F, Yuksekdag, V, Vensentini, N, Ingaramo, A, Sambadaro, G, Caputi, V, Berman, S, Dragotto, P, Kleiban, A, Centurion, N, Giacomi, G, Guerrero, R, Conde, D, Zapata, G, Di Paola, L, Ramos, J, Dran, R, Egido, J, Fernandez, A, Fosco, M, Sassone, S, Sinisi, V, Cartasegna, L, Berli, M, Vilamajo, O, Ferroni, F, Alaguibe, E, D'Amelio, A, Arabetti, C, Arias, L, Belardi, J, Bergesio, L, Berli, F, Borchowiec, S, Buzzetti, C, Cabrini, R, Campisi, V, Cappi, A, Carrizo, R, Berra, F, Costabel, J, Costamagna, O, Damonte, A, De Urquiza, I, Diez, F, Eden, M, Fanuele, M, Voena, F, Torres, M, Funosas, C, Giacomi, M, Gimenez, C, Gurfinkel, E, Had, M, Hansen, V, Hrabar, A, Ingratta, M, Lopez, A, Maehara, G, Maffei, L, Martinelli, A, Martinelli, C, Matkovich, J, Mautner, B, Meirino, A, Munguia, R, Navarro, A, Novas, V, Prados, G, Pontoriero, J, Potito, R, Ricotti, C, Rodriguez, M, Rolandi, F, Palladino, M, Salinger, M, Sanziani, L, Schygiel, P, Sossich, A, Tinto, J, Tonelli, L, Tufare, A, Vallejo, M, Yunis, M, Zillo, M, Zurbrigk, F, Filho, D, Jaber, J, Armaganijan, D, Neto, J, Steffens, A, de Souza, W, de Souza Neto, J, Ribeiro, J, Teixeira, M, Rossi, P, Pires, L, Moreira, D, Jorge, J, Filho, A, Bodanese, L, Montera, M, Del Carlo, C, Rodrigues, T, da Costa, F, Lopes, A, Lopes, R, Araujo, G, Manenti, E, Saraiva, J, Braga, J, Negri, A, Souto, L, Moncada, C, Precoma, D, Roquette, F, Reis, G, Filho, R, Figueiredo, E, Botelho, R, Tavares, C, Frack, C, Saad, J, Finimundi, H, Pisani, C, Chemello, D, Martins, M, Franca, C, Alban, F, Rosito, G, Moraes Junior, J, Tumelero, R, Maia, L, de Almeida, R, do Carmo Borges, N, Ferreira, L, Agliardi, P, Gomes, J, Araujo, V, Nakazone, M, Barbosa, T, Barroso, S, Falchetto, E, Lopes, H, Lemos, M, Biazus, G, Queiroz, L, Camazzola, F, Caporale, M, Cardoso Boscato, S, Chieza, F, Chokr, M, Mingireanov, R, Goes, N, Correa, C, Costa, M, Ortiz, C, da Silva, L, Paulitsch, F, da Silveira, J, Daros, E, de Araujo, G, Del Monaco, M, Dias, C, Dias, M, Wainstein, A, Pizzato, P, Esteves, D, Fabri, P, Fonseca, T, Fernandes, E, Fonseca, C, Costantini, C, Ferraz, R, Freire, F, Gottardo, P, Guanaes, D, Guizzardi, S, Magedanz, E, Igansi, F, Jannuzzi, F, Junior, G, Komar, D, Lino, E, Lopes, D, Junior, O, Lustosa, E, Macagnan, A, Marinho, M, Mazzoni, M, Melo, G, Mortari, L, Mouco, O, Vital, C, Ormundo, C, Emmer, S, Palmegiani, E, Pavani, R, Pereira, L, Pereira, V, Perreira, R, Poletti, S, Fortunato, S, Queirantes, C, Pereira, N, Rech, R, Ribeiro, S, Rodrigues, A, Roesch, H, Reichert, T, Santos, D, Santos, I, Santos, M, Seroqui, M, Silva, S, Soares, L, Spolaor, L, Stoll, C, Duda, N, Trama, L, Unterkircher, B, Valois, M, Vargas, T, Viana, T, Vicente, C, Armaganijan, L, Homem, R, Torres, L, Vila, L, Filho, F, Eggers, G, Gutierrez, C, Arriagada, G, Cardenas, S, Fernandez, B, Conejeros, C, Houzvic, C, Cuevas, P, Montecinos, H, Forero, A, Lanas, F, Gomez, M, Vilches, G, Rey, C, Astudillo, C, Aguilar, J, Campisto, Y, Lara, C, Molina, E, Oyarzon, J, Olguin, V, Vergara, M, Villan, C, Diaz, J, Cantu, R, Zavala, M, Jardines, R, Zavaleta, N, Umana, S, Rosas, E, Esperon, G, Pozas, G, Munoz, E, Hernandez, N, Rendon, A, Ibarra, M, Carrillo, L, Villezca, D, Herrera, C, Prieto, J, Rodriguez, R, Espinosa, E, Martinez, D, Barcena, J, Yong, R, Briones, I, Pons, J, Lopez, H, Ruiz, R, de la Vega, C, Brito, C, Valenzuela, E, Reyes-Sanchez, R, Ruiz, A, Flores, O, Gonzalez, M, Nava, R, Cerda, J, Fierro, O, Campos, P, Alfaro, T, Bellorin, S, Avena, R, Chavarria, M, Espinosa, I, Silva, F, Godoy, K, Felix, E, Garcia, C, Salas, L, Guajardo, P, Gonzalez, S, Izquierdo, T, Ortiz, M, Vasquez, D, Mendoza, N, Morales, J, Nikitina, N, Aybar, S, Ortiz, A, Macias, P, Perez, F, Sanchez, J, Toledano, S, Ramos, C, Castro, V, Cardona, G, Cornejo, M, Salinas, A, Santana, G, Perez, P, Castaneda, A, Cortes, R, Lenz, K, Drexel, H, Foechterle, J, Hagn, C, Podczeck-Schweighofer, A, Huber, K, Winkler, M, Schneeweiss, B, Gegenhuber, A, Lang, W, Eichinger-Hasenauer, S, Kaserer, P, Sykora, J, Rasch, H, Pichler, M, Schaflinger, E, Strohmer, B, Breier, R, Ebner, K, Eischer, L, Freihoff, F, Lischka-Lindner, A, Mark, T, Mirtl, A, Said, A, Stocklocker, C, Vogel, B, Vonbank, A, Wohrer, C, Zanolin, D, Paparella, G, Vandergoten, P, Parque, J, Capiau, L, Vervoort, G, Wollaert, B, Desfontaines, P, Mairesse, G, Boussy, T, Godart, P, De Wolf, A, Voet, J, Heyse, A, Hollanders, G, Anne, W, Vercammen, J, Purnode, P, Blankoff, I, Faes, D, Balthazar, Y, Beutels, M, Marechal, P, Verstraete, S, Xhaet, O, Striekwold, H, Thoeng, J, Hermans, K, Alzand, B, Ascoop, A, Banaeian, F, Barbuto, A, Billiaux, A, Blockmans, M, Bouvy, C, Brike, C, Capiau, H, Casier, T, Bolado, A, De Cleen, D, De Coninck, M, de Vos, M, de Weerdt, N, Delforge, M, Delvigne, M, Denie, D, Derycker, K, Deweerd, E, Dormal, F, Drieghe, S, Everaert, M, Eykerman, T, Feys, E, Ghekiere, M, Gits, F, Hellemans, S, Helvasto, L, Jacobs, C, Lips, S, Mestdagh, I, Nimmegeers, J, Piamonte, V, Pollet, P, Postolache, A, Raepers, M, Raymenants, E, Richa, J, Rombouts, H, Salembier, J, Scheurwegs, C, Semeraro, O, Simons, N, Smessaert, C, Smolders, W, Stockman, I, Tahon, S, Thyssen, V, Tincani, G, Van Durme, F, Van Lier, D, Vandekerckhove, H, Vandekerckhove, Y, Vandenbroeck, D, Vandorpe, A, Vanhalst, E, Vanhauwaert, B, Vantomme, C, Vergauwen, L, Verloove, H, Vydt, T, Weyn, T, Reichert, P, Spacek, R, Machova, V, Zidkova, E, Ludka, O, Olsr, J, Kotik, L, Plocova, K, Racz, B, Ferkl, R, Hubac, J, Kotik, I, Monhart, Z, Burianova, H, Jerabek, O, Pisova, J, Petrova, I, Dedek, V, Honkova, M, Podrazil, P, Spinar, J, Vitovec, J, Novak, M, Lastuvka, J, Durdil, V, Antonova, P, Bockova, L, Bultas, J, Chlumsky, J, Dastychova, L, Drasnar, T, Honek, J, Horejsi, M, Hubacova, V, Janska, L, Kopeckova, I, Kratochvilova, R, Krcova, E, Labrova, R, Lindourkova, A, Lipoldova, J, Lubanda, H, Ludkova, A, Mahdalikova, L, Majernikova, M, Michalik, D, Potuznik, P, Prochazkova, E, Sulc, A, Sveceny, J, Valtova, M, Zidek, M, Zika, J, Nielsen, H, Husted, S, Hintze, U, Rasmussen, S, Bremmelgaard, A, Markenvard, J, Boerger, J, Solgaard, J, Simonsen, P, Loekkegaard, T, Bruun, M, Mertz, J, Dominguez, H, Skagen, K, Egstrup, K, Ibsen, H, Raymond, I, Bang-Hansen, T, Ellervik, C, Eriksen, E, Jensen, L, Jensen, M, Leth, M, Nygaard, A, Schou, M, Therkelsen, A, Tilma, J, Vesterager, K, Airaksinen, J, Arola, O, Koistinen, J, Nappila, H, Peltomaki, K, Rasanen, V, Vasankari, T, Galinier, M, Gottwalles, Y, Paganelli, F, Loiselet, P, Muller, J, Koujan, M, Marquand, A, Destrac, S, Piot, O, Delarche, N, Cebron, J, Boveda, S, Guenoun, M, Guedj-Meynier, D, Galley, D, Ohayon, J, Assouline, S, Zuber, M, Amarenco, P, Ellie, E, Kadouch, J, Fournier, P, Huberman, J, Lemaire, M, Rodier, G, Milandre, L, Vandamme, X, Sibon, I, Neau, J, Mahagne, M, Mielot, A, Bonnefoy, M, Churet, J, Navarre, V, Sellem, F, Monniot, G, Boyes, J, Doucet, B, Martelet, M, Obadia, D, Crousillat, B, Mouallem, J, Bearez, E, Nazeyrollas, P, Brugnaux, J, Fedorowsky, A, Casassus, F, Berneau, J, Chemin, F, Falvo, N, Perron, J, Poulard, J, Barreau, A, Beltra, C, Corrihons, E, Decarsin, N, Dubois, B, Ducasse, E, Giry, X, Kemmel, A, Ledure, S, Lemaire, N, Robin, F, Rosolin, N, Sanchez, D, Suissa, A, Koniger, G, Purr, J, Gerbaulet, U, Kellner, B, Kopf, A, Schafer, T, Zauzig, H, Riegel, P, Hohensee, H, Eissfeller, E, Eder, W, Rehling, G, Glatzel, D, Zutz, S, Heinz, G, Menke, H, Pustelnik, A, Sandow, P, Ludwig, N, Wiswedel, H, Wildenauer, W, Axthelm, C, Schwarz, T, Babyesiza, A, Stuchlik, G, Zimny, H, Kropp, M, Kahl, F, Caspar, A, Omankowsky, S, Lassig, T, Hartmann, H, Lehmann, G, Bindig, H, Hergdt, G, Reimer, D, Hauk, J, Dorsch, W, Dshabrailov, J, Michel, H, Rapp, K, Vormann, R, Mayer, P, Horstmeier, U, Eissing, V, Hey, H, Leuchtgens, H, Lilienweiss, V, Kolitsch, K, Schubert, C, Lauer, H, Buchner, T, Brauer, G, Kamin, S, Muller, K, Abdel-Qader, M, Baumbach, S, Ebert, H, Schwencke, C, Schellong, S, Bernhardt, P, Karolyi, L, Sievers, B, Haverkamp, W, Salbach, P, Rohnisch, J, Schoen, S, Erdle, W, Mueller, T, Mueller, H, Mitrovic, V, Babjakova, Z, Bergner, K, Boehme, S, Bonin, K, Buckert, D, Busch, F, Dichristin, U, Diez, S, Fleck, A, Flint, K, Floegel, H, Fritz, C, Frommhold, R, Gehre, J, Geyer, J, Grytzmann, A, Hahn, M, Helgert, K, Hubert, K, Kirchner-Volker, K, Klein, V, Kroll, D, Krueger, A, Lehmann, R, Mann, L, Maselli, A, Menken, G, Mikes, K, Mortan, H, Nasser, N, Nicolaus, D, Plauskat, A, Pomper, L, Quietzsch, A, Ravenhorst, C, Reichelt, C, Reimer, C, Schaefer, B, Scharrer, S, Schirmer, K, Schmidt, K, Schoene, R, Schulze, J, Schuppe, M, Simon, S, Sommer, S, Spranger, K, Talkenberger, A, Tauber, K, Tetlak, A, Toennishoff, T, Voelkel-Babyesiza, R, Voigts, B, Weiser, U, Wesendorf, S, Wildenauer, S, Wolf, T, Wurziger, J, Zak, J, Ziefle, S, Zincke, S, Vangel, S, Szalai, G, Merkely, B, Kancz, S, Boda, Z, Nagy, A, Laszlo, Z, Matoltsy, A, Gaszner, B, Polgar, P, Habon, T, Noori, E, Juhasz, G, Kanakaridisz, N, Szentpeteri, I, Juhasz, F, Vertes, A, Papp, A, May, Z, Ferenczi, J, Egyutt, M, Kis, E, Engelthaler, G, Szantai, G, Fulop, E, Gombos, P, Gulyas, D, Jen, P, Kiralyhazine Gyorke, E, Kovacs, M, Kovacsne Levang, S, Marianna, S, Radics, Z, Sydo, N, Szalo, R, Szilagyi, A, Sztanyik, F, Vandrus, B, Tiraferri, E, Santoro, R, Testa, S, Di Minno, G, Moia, M, Caimi, T, Martini, G, Tessitori, M, Cappelli, R, Poli, D, Quintavalla, R, Melone, F, Cosmi, F, Pizzini, A, Piseddu, G, Fanelli, R, Latella, C, Santi, R, Pancaldi, L, De Cristofaro, R, Palareti, G, De Blasio, A, Salerno Uriarte, J, Minetti, F, Pogliani, E, Lonati, L, Accogli, M, Ciampani, N, Malengo, S, Feola, M, Raisaro, A, Fattore, L, Grilli, P, Germini, F, Settimi, M, Alunni, M, Duranti, G, Tedeschi, L, Baglioni, G, Avanzino, G, Berardi, M, Pannacci, V, Giombolini, A, Nicoli, S, Scarponi, T, Allasia, B, Ricciarini, P, Nasorri, R, Argena, A, Bossolasco, P, Ronchini, P, Filippi, A, Tradati, F, Bulla, C, Donzelli, L, Foppa, L, Bottarelli, M, Tomasello, A, Mauric, A, Femiano, C, Reggio, R, Lillo, F, Mariani, A, Forcignano, F, Volpe, M, D'Avino, M, Bongiorni, M, Severi, S, Capucci, A, Lodigiani, C, Salomone, E, Serviddio, G, Tondo, C, Golino, P, Mazzone, C, Iacopino, S, Pengo, V, Galvani, M, Moretti, L, Ambrosino, P, Banfi, E, Biagioli, V, Bianchi, A, Boggian, G, Breschi, M, Brusorio, S, Calcagnoli, F, Campagna, G, Carpenedo, M, Ciabatta, C, Ciliberti, G, Cimmino, G, D'Arienzo, C, Di Gennaro, L, Fedele, M, Ferrini, P, Granzow, K, Guazzaloca, G, Guerra, F, Lo Buglio, A, Longo, S, Macellari, F, Mesolella, E, Mollica Poeta, E, Occhilupo, P, Oriana, V, Rangel, G, Salomone, L, Scaccianoce, A, Scarone, C, Segreti, L, Sottilota, G, Villani, R, Zecca, C, Ruiter, J, Klomps, H, Bongaerts, M, Pieterse, M, Guldener, C, Herrman, J, Lochorn, G, Lucassen, A, Adriaansen, H, The, S, Nierop, P, Hoogslag, P, Hermans, W, Groenemeijer, B, Terpstra, W, Buiks, C, Boersma, L, Boersma-Slootweg, M, Bosman, F, Bosschaert, M, Bruin, S, Danse, I, De Graaf, J, de Graauw, J, Debordes, M, Dols, S, Geerlings, F, Gorrebeeck, K, Jerzewski, A, Jetten, W, Kelderman, M, Kloosterman, T, Koomen, E, Krikken, J, Melman, P, Mulder, R, Pronk, A, Stallinga-de Vos, A, te Kaat, J, Tonino, P, Uppelschoten, B, van de Loo, R, van der Kley, T, van Leeuwen, G, van Putten, J, Westerman, L, Berge, E, Sirnes, P, Gjertsen, E, Hole, T, Erga, K, Hallaraker, A, Skjelvan, G, Ostrem, A, Ghezai, B, Svilaas, A, Christersson, P, Oien, T, Hoegh Henrichsen, S, Berg-Johansen, J, Otterstad, J, Antonsen, H, Ausen, K, Claussen, H, Dominguez, I, Jekthammer, A, Lensebraaten, A, Nilsen, V, O'Donovan, M, Ringdalen, K, Strand, S, Korzeniak, R, Gieroba, A, Biedrzycka, M, Ogorek, M, Wozakowska-Kaplon, B, Loboz-Grudzien, K, Kosior, J, Supinski, W, Kuzniar, J, Zaluska, R, Hiczkiewicz, J, Swiatkowska-Byczynska, L, Kucharski, L, Gruchala, M, Minc, P, Olszewski, M, Kania, G, Krzciuk, M, Lajkowski, Z, Ostrowska-Pomian, B, Lewczuk, J, Zinka, E, Karczmarczyk, A, Chmielnicka-Pruszczynska, M, Trusz-Gluza, M, Opolski, G, Bronisz, M, Glanowska, G, Ruszkowski, P, Jaworska, K, Sciborski, R, Okopien, B, Kukla, P, Wozniak-Skowerska, I, Galbas, K, Cymerman, K, Jurowiecki, J, Miekus, P, Myszka, W, Mazur, S, Lysek, R, Baszak, J, Rusicka-Piekarz, T, Raczak, G, Domanska, E, Nessler, J, Lesnik, J, Ambicka, M, Andrzejewski, D, Araminowicz, J, Barszcz, A, Bartkowiak, R, Bartnik, J, Basiak, M, Bekieszczuk, E, Bernat, L, Biedrzycki, L, Biernacka, A, Blaszczyk, D, Broton, E, Brzozowski, W, Brzustowska, M, Bzymek, R, Chmielowski, A, Chojnowski, P, Cichomski, R, Cieslak, K, Cieszynska, A, Curyllo, B, Czamara, M, Danilowicz-Szymanowicz, L, Dolecka, B, Drelich, L, Dudzik-Richter, B, Dybala, T, Dziuba, M, Faron, W, Figura-Chmielewska, M, Frankiewicz, A, Gadzinski, W, Gasior, E, Gosciniecka, B, Gutknecht, P, Guziewicz, M, Jackun-Podlesna, A, Jaguszewska, G, Jankielewicz, J, Jaremczuk-Kaczmarczyk, A, Jargiello-Baszak, M, Jarzebowski, A, Jaskulska-Niedziela, E, Jaworska-Drozdowska, M, Kabat, J, Kaczmarzyk-Radka, A, Kalin, K, Kaliszczak, R, Kiliszek, M, Klata, M, Kluczewski, M, Kobielusz-Gembala, I, Kochanska, E, Kociolek, D, Kolodzinska, A, Komlo, A, Konopka, A, Korczowska, E, Kowal, E, Kowalczyk, H, Kremis, E, Kruczyk, D, Krzesiak-Lodyga, A, Krzyzanowski, M, Kurdzielewicz, W, Kustrzycka-Kratochwil, D, Lesniewska-Krynska, D, Leszczynski, J, Lewicka, E, Lichota, E, Lip, K, Loboz-Rudnicka, M, Luka, J, Lysek-Jozefowicz, A, Machnikowska, M, Majewska, K, Mariankowski, R, Markiewicz, A, Mazur, M, Metzgier-Gumiela, A, Miedlar, E, Mielcarek, M, Neubauer-Geryk, J, Niedek, J, Niemirycz-Makurat, A, Nowak, A, Nowak, S, Opielowska-Nowak, B, Ozgowicz, M, Pawelska-Buczen, A, Pawlik-Rak, E, Piotrowicz, R, Ptaszynski, P, Raczynska, A, Rogowski, W, Romanek, J, Romaszkiewicz, R, Rostoff, P, Roszczyk, N, Rozewska-Furmanek, D, Rychta, J, Rzyczkowska, B, Sidor, A, Skalska, J, Smichura, M, Splawski, M, Staneta, P, Staniszewska, E, Starak-Marciniak, J, Stopyra-Poczatek, M, Sukiennik-Kujawa, M, Szafranski, J, Szalecki, P, Szczepanska, A, Szkrobka, W, Szuchnik, E, Szulowska, A, Szumczyk-Muszytowska, G, Szwoch, M, Traczyk, T, Troszczynska, M, Trzcinski, G, Tybura, S, Walasik, P, Wegrzynowska, M, Wesolowska, K, Wieczorek, W, Wierzbicka, A, Wilczewski, P, Wilgat-Szecowka, M, Wojewoda, P, Wojnowski, L, Wrobel, M, Zakutynska-Kowalczyk, K, Zyczynska-Szmon, M, Eltishcheva, V, Libis, R, Tereshchenko, S, Popov, S, Kamalov, G, Belenky, D, Zateyshchikova, A, Kropacheva, E, Kolesnikova, A, Nikolaev, K, Egorova, L, Khokhlov, A, Yakupov, E, Poltavskaya, M, Zateyshchikov, D, Drapkina, O, Vishnevsky, A, Barbarash, O, Miller, O, Aleksandrova, E, Chizhov, P, Sergeev, M, Shutemova, E, Mazur, E, Zrazhevskiy, K, Novikova, T, Kostenko, V, Moiseeva, Y, Polkanova, E, Sobolev, K, Rossovskaya, M, Zubeeva, G, Shapovalova, Y, Nagibovich, O, Edin, A, Agakhanyan, A, Batalov, R, Belenkova, Y, Bitakova, F, Chugunnaya, S, Dumikyan, A, Erofeeva, S, Gorbunova, E, Gorshkova, T, Gubanov, A, Gurmach, M, Ivanova, Y, Kolesova, T, Konyushenko, D, Korneeva, O, Kropova, O, Kuchuk, P, Kungurtseva, O, Kupriyanova, T, Kurylo, B, Kuvanova, M, Lebedeva, O, Lileeva, E, Machilskaya, O, Medvedeva, T, Monako, G, Motylev, I, Nagibovich, G, Novikova, E, Orlov, Y, Osmolovskaya, Y, Ovsannikova, A, Platonov, D, Rachkova, S, Sinitsina, O, Speshilova, S, Suslova, O, Ushakov, A, Volodicheva, O, Zemlianskaia, O, Zhirov, I, Zhuravleva, E, Zotova, I, Garcia, P, Fernandez, M, Tercedor, L, Iparraguirre, S, Monserrat, P, Contreras, E, Rafecas, J, Carrasco, J, Pavia, P, Pajuelo, C, Serrano, C, Alonso, L, Klein, J, Juanatey, J, Esquivias, G, Collado, I, Piquero, H, Cuixart, C, Morato, M, Llibre, J, Gutierrez, M, Gonzalo, F, Fernandez, C, Plana, N, Montserrat, E, Alia, J, Oliva, M, Sanmartin, J, Alvarez, M, Melenchon, J, Vera, T, Soriano, F, Riesco, L, Macian, M, Granado, J, Navarro, M, Sales, J, Perez, J, Caamano, M, Gomez, G, Romo, A, Diaz, M, Alonso, C, Alvarez, D, Amaro, M, Andere, N, Villar, J, Ochoa, R, Austria, A, Barbeira, S, Feu, E, Bartes, A, Munoz, V, Jimenez, F, Tijuan, A, Ramirez, J, Ramos, M, Martinez, E, Moreno, M, Corchado, G, Gil, M, Orive, M, Fernandez, D, del Misterio, M, Alsina, R, Cabrera, A, de Faria, J, Costas, S, Marco, M, Dachs, M, Lopez, C, Borras, A, Madariaga, A, Espallargas, A, Escobar, E, Mas, E, Ferrer, A, Fosch, J, Bermudez, M, Millan, V, Saenz, M, Gomez, C, Perez, Y, Segovia, A, Gonzalez, P, Grigorian, L, Molina, A, del Val, M, Maeso, B, Rodriguez, E, Garcia, A, Besa, B, Salvadores, P, Bouzamayor, M, Lasuncion, I, Gort, L, Molina, M, Lopez, M, Rey, A, Guerra, J, Marcus, S, Vila, A, Mena, M, Mazon, P, Zurita, F, Millan, G, Alia, P, Montes, D, Munoz, R, Palma, A, Figueroa, H, Ortega, V, Cortes, C, Tomera, D, Merchan, N, Ibar, I, Garcia, E, Armayor, M, Carasa, M, Prieto, I, Quintern, V, Renom, R, Diaz, L, Rios, V, Sola, L, Rivera, R, Robiro, X, Roca, M, Saumell, C, Rodrigo, C, Garcia, M, Jimenez, S, Calderon, P, Mendez, L, Parra, S, Santolaya, C, Sanz, M, Blanco, A, Serralvo, E, Sierra, N, Valero, C, Lopez, J, Fontanillas, M, Riera, M, Tobajas, G, Torres, C, Marques, J, Pastor, M, Wirdby, A, Linden, J, Henriksson, K, Elmersson, M, Egilsson, A, Borjesson, U, Svard, G, Liu, B, Lindh, A, Olsson, L, Gustavsson, M, Andersson, L, Benson, L, Bothin, C, Hajimirsadeghi, A, Kadir, K, Ericsson, M, Ohlsson, A, Lindvall, H, Svensson, P, Thorne, K, Handel, H, Platonov, P, Eriksson, B, Timberg, I, Romberg, K, Crisby, M, Karlsson, J, Jensen, S, Andersson, A, Malmqvist, L, Martinsson, B, Bernsten, F, Engdahl, J, Thulin, J, Hot-Bjelac, A, Stalby, P, Aaroe, H, Ahbeck, E, Ahlmark, H, Al-Khalili, F, Bonkowski, G, Dzeletovic, S, Ekstrand, A, Eriksson, G, Floren, K, Grassjo, C, Hahn, S, Jaensson, P, Jansson, B, Jansson, J, Kangert, R, Koch, A, Kusiak, D, Lettenstrom, A, Lindberg, A, Lindholm, C, Mannermyr, A, Mansson, K, Millborg, M, Nilsson, C, Ohlin, A, Olofsson, A, Osberg, A, Pedersen, A, Risbecker, K, Rosenberg, K, Samuelsson, J, Shayesteh, M, Skoglund, K, Stjernberg, M, Thorsen, C, Beer, J, Debrunner, J, Amstutz, D, Bruegger, J, Elise, G, Grau, A, Guinand, A, Henriette, I, Saga, E, Winnik, S, Rudyk, I, Tseluyko, V, Karpenko, O, Zhurba, S, Kraiz, I, Kupnovytska, I, Serediuk, N, Mostovoy, Y, Ushakov, O, Koval, O, Kovalskyi, I, Svyshchenko, Y, Sychov, O, Stanislavchuk, M, Kraydashenko, O, Yagensky, A, Tykhonova, S, Fushtey, I, Belegai, R, Berko, G, Burdeuna, L, Chabanna, O, Daniuk, I, Ivanov, A, Kamenska, E, Kaplan, P, Khyzhnyak, O, Kizim, S, Matova, O, Medentseva, O, Mochonyi, V, Mospan, M, Nemtsova, V, Ovdiienko, T, Palamarchuk, O, Pavelko, M, Petrovskyy, R, Plevak, D, Proshak, O, Pyvovar, S, Rasputina, L, Romanenko, O, Romanova, O, Sapatyi, A, Shumakov, O, Stets, R, Todoriuk, L, Varenov, V, Chauhan, N, Goodwin, D, Saunders, P, Evans, R, Leese, J, Jhittay, P, Ross, A, Kainth, M, Pickavance, G, Mcdonnell, J, Williams, A, Gooding, T, Wagner, H, Suryani, S, Singal, A, Sircar, S, Bilas, R, Hutchinson, P, Wakeman, A, Stokes, M, Paul, N, Aziz, M, Ramesh, C, Wilson, P, Franklin, S, Fairhead, S, Thompson, J, St Joseph, V, Taylor, G, Tragen, D, Seamark, D, Paul, C, Richardson, M, Jefferies, A, Sharp, H, Jones, H, Giles, C, Page, M, Oginni, O, Aldegather, J, Wetherwell, S, Lumb, W, Evans, P, Scouller, F, Macey, N, Stipp, Y, West, R, Thurston, S, Wadeson, P, Matthews, J, Pandya, P, Gallagher, A, Railton, T, Sinha, B, Russell, D, Davies, J, Ainsworth, P, Jones, C, Weeks, P, Eden, J, Kernick, D, Murdoch, W, Lumley, L, Patel, R, Wong, S, Saigol, M, Ladha, K, Douglas, K, Cumberlidge, D, Bradshaw, C, Van Zon, G, Jones, K, Thomas, M, Watson, E, Sarai, B, Ahmad, N, Willcock, W, Cairns, J, Sathananthan, S, de Kare-Silver, N, Gilliland, A, Strieder, E, Howitt, A, Vishwanathan, B, Bird, N, Gray, D, Clark, M, Bisatt, J, Litchfield, J, Fisher, E, Fooks, T, Kelsall, A, Alborough, E, Wakeling, J, Parfitt, M, Milne, K, Rogers, S, Priyadharshan, R, Oliver, J, Davies, E, Abushal, S, Jacobs, M, Hutton, C, Walls, N, Thompson, R, Chigbo, C, Zaidi, S, Howard, M, Butter, K, Barrow, S, Little, H, Haq, I, Gibbons, L, Glencross, S, Mcleod, A, Poland, K, Mulholland, C, Warke, A, Conn, P, Burns, G, Smith, R, Lowe, S, Kamath, R, Dau, H, Webster, J, Hodgins, I, Vercoe, S, Roome, P, Pinnock, H, Patel, J, Ali, A, Hart, N, Davies, R, Stuart, E, Neden, C, Danielsen, M, Heath, R, Sharma, P, Galloway, S, Hawkins, C, Oliver, R, Aylward, M, Mannion, S, Braddick, M, Edwards, D, Rothwell, A, Sabir, A, Choudhary, F, Khalaque, S, Wilson, A, Peters, S, Coulson, W, Roberts, N, Heer, A, Coates, S, Ward, B, Jackson, D, Walton, S, Shepherd, D, Sterry, M, Wong, T, Boon, M, Bunney, R, Haria-Shah, R, Baron, R, Davies, S, Schatzberger, T, Hargreaves, N, Stephenson, T, Batson, R, Lucraft, L, Myhill, T, Estifano, S, Geatch, D, Wilkinson, J, Veale, R, Forshaw, K, Davies, T, Zaman, K, Vinson, P, Liley, C, Bandrapalli, M, Mcginty, P, Wastling, R, Mceleny, P, Beattie, A, Cooke, P, Wong, M, Gunasegaram, J, Pugsley, M, Ahmad, S, A'Court, C, Ayers, J, Bennett, J, Cartwright, S, Dobson, S, Dooldeniya, C, Flynn, A, Fox, R, Goram, J, Halpin, A, Hay, A, Jacobs, P, Jeffers, L, Lomax, L, Munro, I, Muvva, R, Nadaph, M, Powell, K, Randfield, S, Redpath, D, Reed, R, Rickenbach, M, Rogers, G, Seamark, C, Shewring, J, Simmons, P, Simper, H, Stoddart, H, Sword, A, Thomas, N, Thomson, A, Blenkhorn, A, Singh, B, Van Gaal, W, Abhayaratna, W, Lehman, R, Roberts-Thomson, P, Kilian, J, Coulshed, D, Catanchin, A, Colquhoun, D, Kiat, H, Eccleston, D, French, J, Zimmett, L, Ayres, B, Phan, T, Blombery, P, Crimmins, D, O'Donnell, D, Choi, A, Astridge, P, Arstall, M, Jepson, N, Binnekamp, M, Lee, A, Rogers, J, Starmer, G, Carroll, P, Faunt, J, Aggarwala, A, Barry, L, Batta, C, Beveridge, R, Black, A, Bonner, M, Boys, J, Buckley, E, Campo, M, Carlton, L, Connelly, A, Conway, B, Cresp, D, Dimitri, H, Dixon, S, Dolman, M, Duroux, M, Eskandari, M, Eslick, R, Ferreira-Jardim, A, Fetahovic, T, Fitzpatrick, D, Geraghty, R, Gibbs, J, Grabek, T, Modi, M, Hayes, K, Hegde, M, Hesketh, L, Hoffmann, B, Johnson, K, Juergens, C, Kassam, I, Lawlor, V, Lehman, M, Lehman, S, Leung, D, Mackay, S, Mackenzie, M, Mccarthy, C, Mcintosh, C, Mckeon, L, Morrison, H, Mussap, C, Myers, J, Nagalingam, V, Oldfield, G, O'May, V, Palmer, J, Parsons, L, Patching, K, Patching, T, Paul, V, Plotz, M, Preston, S, Rashad, H, Ratcliffe, M, Raynes, S, Rose, J, Sanders, L, Seremetkoska, M, Setio, H, Shone, S, Shrestha, P, Singh, C, Singleton, C, Stoyanov, N, Sutcliffe, S, Swaraj, K, Tarrant, J, Thompson, S, Tsay, I, Vorster, M, Waldman, A, Wallis, L, Wilford, E, Wong, K, Luton, R, Gupta, M, Pandey, A, Cheung, S, Leader, R, Beaudry, P, Ayala-Paredes, F, Berlingieri, J, Heath, J, Poirier, G, Du Preez, M, Nadeau, R, Dresser, G, Dhillon, R, Hruczkowski, T, Schweitzer, B, Coutu, B, Angaran, P, Macdonald, P, Vizel, S, Fikry, S, Parkash, R, Lavoie, A, Cha, J, Ramjattan, B, Bonet, J, Ahmad, K, Aro, L, Aves, T, Beaudry, K, Bergeron, C, Bigcanoe, J, Bignell, N, Breakwell, L, Burke, E, Carroll, L, Clarke, B, Cleveland, T, Daheb, S, Dehghani, P, Denis, I, Djaidani, Z, Dorian, P, Douglass, S, Dunnigan, J, Ewert, A, Farquhar, D, Fearon, A, Ferleyko, L, Fournier, D, Fox, B, Grenier, M, Gulliver, W, Haveman, K, Hines, C, Hines, K, Jackson, A, Jean, C, Jethoo, G, Kahlon, R, Kelly, S, Kim, R, Korley, V, Kornder, J, Kwan, L, Largy, J, Lewis, C, Lewis, S, Mangat, I, Moor, R, Navratil, J, Neas, I, Otis, J, Otis, R, Pandey, M, Petrie, F, Pinter, A, Raines, M, Roberts, P, Robinson, M, Sas, G, Schulman, S, Snell, L, Spearson, S, Stevenson, J, Trahey, T, Wright, D, El-Aziz, A, Seif, S, El Din, M, El Etriby, S, Elbahry, A, El-Etreby, A, Elkhadem, M, Katta, A, Khairy, T, Mowafy, A, Nawar, M, Ohanissian, A, Reda, A, Reda, M, Salem, H, Sami, N, Samir, S, Setiha, M, Sobhy, M, Soliman, A, Taha, N, Tawfik, M, Zaatout, E, Kettles, D, Bayat, J, Siebert, H, Horak, A, Kelfkens, Y, Garda, R, Pillay, T, Guerra, M, van Zyl, L, Theron, H, Murray, A, Louw, R, Greyling, D, Mntla, P, Ueckermann, V, Loghdey, R, Ismail, S, Ahmed, F, Engelbrecht, J, Ramdass, A, Maharajh, S, Oosthuysen, W, Angel, G, Bester, C, Booysen, M, Boshoff, C, Cannon, C, Cassimjee, S, Chami, C, Conway, G, Davids, A, de Meyer, L, Du Plessis, G, Ellis, T, Henley, L, Karsten, M, Loyd, E, Marks, J, Mavhusa, L, Mostert, M, Page, A, Rikhotso, L, Salie, M, Sasto, J, Shaik, F, Skein, A, Smith, L, Tarr, G, Tau, T, van Zyl, F, Yousef, G, Agrawal, A, Nathani, M, Ibrahim, M, Esheiba, E, Singh, R, Naguib, A, Abu-Mahfouz, M, Al Omairi, M, Al Naeemi, A, Maruthanayagam, R, Bazargani, N, Wassef, A, Gupta, R, Khan, M, Subbaraman, B, Abdul, A, Al Mulla, A, El Bardisy, S, Haridas, P, Jadhav, S, Magdaluyo, K, Makdad, M, Maqsood, I, Mohamed, R, Sharma, N, Sharma, R, Thanzeel, M, Canosa, R, Rama, P, Blumberg, E, Garcia, J, Mullen, P, Wilson, V, Quick, A, Ferrick, K, Kutayli, W, Cox, M, Franco, M, Falkowski, S, Mendelson, R, Williams, M, Miller, S, Beach, S, Alfieri, A, Gutowski, T, Haque, I, Reddy, R, Ahmed, W, Delafontaine, P, Diercks, D, Theodoro, D, Remmel, K, Alberts, M, Ison, R, Noveck, H, Duffy, P, Pitta, S, Nishijima, D, Treasure, C, Asafu-Adjaye, N, Ball, K, Bartlett, M, Bentley, M, Bowers, S, Brown, A, Browne, A, Cameron-Watts, J, Canova, M, Cassidy, D, Cervellione, K, Congal, S, Depauw, J, Dickerson, A, Eley, M, Evans, L, Felpel, S, Ferdinand, K, Fielder, D, Gentry, P, Haideri, A, Hakimi, F, Harbour, T, Hartranft, E, Hawkins, B, Headlee, M, Henson, L, Herrick, C, Hicks, T, Jasinski, S, Jones, A, Jones, L, Jones, P, Karl, S, Keeling, M, Kerr, J, Knowles, P, Langdon, J, Lay, M, Lee, J, Lincoln, T, Malone, E, Merliss, A, Merritt, D, Minardo, J, Mooso, B, Orosco, C, Palumbo, V, Parker, M, Parrott, T, Paserchia, S, Pearl, G, Peterson, J, Pickelsimer, N, Purcell, T, Raynor, J, Raziano, S, Richard, C, Richardson, T, Robertson, C, Sage, A, Sanghera, T, Shaw, P, Shoemaker, J, Smith, K, Stephanie, B, Thatcher, A, Theobald, H, Thompson, N, Treasure, L, Tripti, T, Verdi, C, Worthy, V, Jerjes-Sanchez, C., Corbalan, R., Barretto, A. C. P., Luciardi, H. L., Allu, J., Illingworth, L., Pieper, K. S., Kayani, G., Fitzmaurice, D. A., Goto, S., Hacke, W., Mantovani, L. G., Turpie, A. G. G., Gersh, B. J., Gibbs, H., Brodmann, M., Cools, F., Connolly, S. J., Spyropoulos, A., Eikelboom, J., Hu, D., Jansky, P., Nielsen, J. D., Ragy, H., Raatikainen, P., Le Heuzey, J. -Y., Darius, H., Keltai, M., Kakkar, S., Sawhney, J. P. S., Agnelli, G., Ambrosio, G., Koretsune, Y., Diaz, C. J. S., ten Cate, H., Atar, D., Stepinska, J., Panchenko, E., Lim, T. W., Jacobson, B., Oh, S., Vinolas, X., Rosenqvist, M., Steffel, J., Angchaisuksiri, P., Parkhomenko, A., Al Mahmeed, W., Chen, K. N., Zhao, Y. S., Zhang, H. Q., Chen, J. Z., Cao, S. P., Wang, D. W., Yang, Y. J., Li, W. H., Yin, Y. H., Tao, G. Z., Yang, P., Chen, Y. M., He, S. H., Wang, Y., Fu, G. S., Li, X., Wu, T. G., Cheng, X. S., Yan, X. W., Zhao, R. P., Chen, M. S., Xiong, L. G., Chen, P., Jiao, Y., Guo, Y., Xue, L., Wang, F. Z., Li, H., Yang, Z. M., Bai, C. L., Chen, J., Chen, J. Y., Chen, X., Feng, S., Fu, Q. H., Gao, X. J., Guo, W. N., He, R. H., He, X. A., Hu, X. S., Huang, X. F., Li, B., Li, J., Li, L., Li, Y. H., Liu, T. T., Liu, W. L., Liu, Y. Y., Lu, Z. C., Luo, X. L., Ma, T. Y., Peng, J. Q., Sheng, X., Shi, X. J., Sun, Y. H., Tian, G., Wang, K., Wang, L., Wu, R. N., Xie, Q., Xu, R. Y., Yang, J. S., Yang, L. L., Yang, Q., Ye, Y., Yu, H. Y., Yu, J. H., Yu, T., Zhai, H., Zhan, Q., Zhang, G. S., Zhang, Q., Zhang, R., Zhang, Y., Zheng, W. Y., Zhou, B., Zhou, Z. H., Zhu, X. Y., Jadhav, P., Durgaprasad, R., Ravi Shankar, A. G., Rajput, R. K., Bhargava, K., Sarma, R., Srinivas, A., Roy, D., Nagamalesh, U. M., Chopda, M., Kishore, R., Kulkarni, G., Chandwani, P., Pothiwala, R. A., Padinhare Purayil, M., Shah, S., Chawla, K., Kothiwale, V. A., Raghuraman, B., Vijayaraghavan, G., Vijan, V. M., Bantwal, G., Bisne, V., Khan, A., Gupta, J. B., Kumar, S., Jain, D., Abraham, S., Adak, D., Barai, A., Begum, H., Bhattacharjee, P., Dargude, M., Davies, D., Deshpande, B., Dhakrao, P., Dhyani, V., Duhan, S., Earath, M., Ganatra, A., Giradkar, S., Jain, V., Karthikeyan, R., Kasala, L., Kaur, S., Krishnappa, S., Lawande, A., Lokesh, B., Madarkar, N., Meena, R., More, P., Naik, D., Prashanth, K., Rao, M., Rao, N. M., Sadhu, N., Shah, D., Sharma, M., Shiva, P., Singhal, S., Suresh, S., Vanajakshamma, V., Panse, S. G., Kanamori, S., Yamamoto, K., Kumagai, K., Katsuda, Y., Sadamatsu, K., Toyota, F., Mizuno, Y., Misumi, I., Noguchi, H., Ando, S., Suetsugu, T., Minamoto, M., Oda, H., Shiraishi, K., Adachi, S., Chiba, K., Norita, H., Tsuruta, M., Koyanagi, T., Ando, H., Higashi, T., Okada, K., Azakami, S., Komaki, S., Kumeda, K., Murayama, T., Matsumura, J., Oba, Y., Sonoda, R., Goto, K., Minoda, K., Haraguchi, Y., Suefuji, H., Miyagi, H., Kato, H., Nakamura, T., Nandate, H., Zaitsu, R., Fujiura, Y., Yoshimura, A., Numata, H., Ogawa, J., Tatematsu, H., Kamogawa, Y., Murakami, K., Wakasa, Y., Yamasawa, M., Maekawa, H., Abe, S., Kihara, H., Tsunoda, S., Saito, K., Fudo, T., Obunai, K., Tachibana, H., Oba, I., Kuwahata, T., Higa, S., Gushiken, M., Eto, T., Yoshida, H., Ikeda, D., Ishizawa, M., Nakatsuka, M., Murata, K., Ogurusu, C., Shimoyama, M., Akutsu, M., Takamura, I., Hoshino, F., Yokota, N., Iwao, T., Tsuchida, K., Takeuchi, M., Hatori, Y., Kitami, Y., Nakamura, Y., Oyama, R., Ageta, M., Go, Y., Mishima, K., Unoki, T., Morii, S., Shiga, Y., Sumi, H., Nagatomo, T., Sanno, K., Fujisawa, K., Atsuchi, Y., Nagoshi, T., Seto, T., Tabuchi, T., Kameko, M., Nii, K., Oshiro, K., Takezawa, H., Nagano, S., Miyamoto, N., Iwaki, M., Fujii, M., Okawa, M., Abe, M., Saito, T., Mito, T., Nagao, K., Minami, J., Mita, T., Sakuma, I., Taguchi, T., Marusaki, S., Doi, H., Tanaka, M., Fujito, T., Matsuta, M., Kusumoto, T., Kakinoki, S., Ashida, K., Yoshizawa, N., Agata, J., Arasaki, O., Manita, M., Ikemura, M., Fukuoka, S., Murakami, H., Matsukawa, S., Hata, Y., Taniguchi, T., Ko, T., Kubo, H., Imamaki, M., Akiyama, M., Inagaki, M., Odakura, H., Ueda, T., Katsube, Y., Nakata, A., Watanabe, H., Techigawara, M., Igarashi, M., Taga, K., Kimura, T., Tomimoto, S., Shibuya, M., Nakano, M., Ito, K., Seo, T., Hiramitsu, S., Hosokawa, H., Hoshiai, M., Hibino, M., Miyagawa, K., Horie, H., Sugishita, N., Soma, A., Neya, K., Yoshida, T., Mizuguchi, M., Ishiguro, M., Minagawa, T., Wada, M., Mukawa, H., Okuda, F., Nagasaka, S., Abe, Y., Adachi, T., Akahane, K., Amano, T., Aoki, K., Aoyama, T., Arai, H., Arima, S., Arino, T., Asano, H., Asano, T., Azuma, J., Baba, T., Betsuyaku, T., Chibana, H., Date, H., Doiuchi, J., Emura, Y., Endo, M., Fujii, Y., Fujiki, R., Fujisawa, A., Fujisawa, Y., Fukuda, T., Fukui, T., Furukawa, N., Furukawa, T., Furumoto, W., Goto, T., Hamaoka, M., Hanazono, N., Hasegawa, K., Hatsuno, T., Hayashi, Y., Higuchi, K., Hirasawa, K., Hirayama, H., Hirose, M., Hirota, S., Honda, M., Ido, T., Iiji, O., Ikeda, H., Ikeda, K., Ikeoka, K., Imaizumi, M., Inaba, H., Inoue, T., Iseki, F., Ishihara, A., Ishioka, N., Ito, N., Iwase, T., Kakuda, H., Kamata, J., Kanai, H., Kanda, H., Kaneko, M., Kano, H., Kasai, T., Kato, T., Kato, Y., Kawada, Y., Kawai, K., Kawakami, K., Kawakami, S., Kawamoto, T., Kawano, S., Kim, J., Kira, T., Kitazawa, H., Kitazumi, H., Kito, T., Kobayashi, T., Koeda, T., Kojima, J., Komatsu, H., Komatsu, I., Koshibu, Y., Kotani, T., Kozuka, T., Kumai, Y., Kumazaki, T., Maeda, I., Maeda, K., Maruyama, Y., Matsui, S., Matsushita, K., Matsuura, Y., Mineoi, K., Mitsuhashi, H., Miura, N., Miyaguchi, S., Miyajima, S., Miyamoto, H., Miyashita, A., Miyata, S., Mizuguchi, I., Mizuno, A., Mori, T., Moriai, O., Morishita, K., Murai, O., Nagai, S., Nagata, E., Nagata, H., Nakagomi, A., Nakahara, S., Nakamura, M., Nakamura, R., Nakanishi, N., Nakayama, T., Nakazato, R., Nanke, T., Nariyama, J., Niijima, Y., Niinuma, H., Nishida, Y., Nishihata, Y., Nishino, K., Nishioka, H., Nishizawa, K., Niwa, I., Nomura, K., Nomura, S., Nozoe, M., Ogawa, T., Ohara, N., Okada, M., Okamoto, K., Okita, H., Okuyama, M., Ono, H., Ono, T., Pearce, Y. O., Oriso, S., Ota, A., Otaki, E., Saito, Y., Sakai, H., Sakamoto, N., Sakamoto, Y., Samejima, Y., Sasagawa, Y., Sasaguri, H., Sasaki, A., Sasaki, T., Sato, K., Sawano, M., Seki, S., Sekine, Y., Seta, Y., Sezaki, K., Shibata, N., Shiina, Y., Shimono, H., Shimoyama, Y., Shindo, T., Shinohara, H., Shinohe, R., Shinozuka, T., Shirai, T., Shiraiwa, T., Shozawa, Y., Suga, T., Sugimoto, C., Suzuki, K., Suzuki, S., Suzuki, Y., Tada, M., Taguchi, A., Takagi, T., Takagi, Y., Takahashi, K., Takahashi, S., Takai, H., Takanaka, C., Take, S., Takeda, H., Takei, K., Takenaka, K., Tana, T., Tanabe, G., Taya, K., Teragawa, H., Tohyo, S., Toru, S., Tsuchiya, Y., Tsuji, T., Tsuzaki, K., Uchiyama, H., Ueda, O., Ueyama, Y., Wakaki, N., Wakiyama, T., Washizuka, T., Watanabe, M., Yamada, T., Yamagishi, T., Yamaguchi, H., Yamamoto, T., Yamaura, M., Yamazoe, M., Yasui, K., Yokoyama, Y., Yoshida, K., Ching, C. K., Foo, C. G., Chow, J. H., Chen, D. D., Jaufeerally, F. R., Lee, Y. M., Lim, G., Lim, W. T., Thng, S., Yap, S. Y., Yeo, C., Pak, H. N., Kim, J. -B., Kim, J. H., Jang, S. -W., Kim, D. H., Ryu, D. R., Park, S. W., Kim, D. -K., Choi, D. J., Oh, Y. S., Cho, M. -C., Kim, S. -H., Jeon, H. -K., Shin, D. -G., Park, J. S., Park, H. K., Han, S. -J., Sung, J. H., Cho, J. -G., Nam, G. -B., On, Y. K., Lim, H. E., Kwak, J. J., Cha, T. -J., Hong, T. J., Park, S. H., Yoon, J. H., Kim, N. -H., Kim, K. -S., Jung, B. C., Hwang, G. -S., Kim, C. -J., Kim, D. B., Ahn, J. J., An, H. J., Bae, H., Baek, A. L., Chi, W. J., Choi, E. A., Choi, E. H., Choi, H. K., Choi, H. S., Han, S., Heo, E. S., Her, K. O., Hwang, S. W., Jang, E. M., Jang, H. -S., Jang, S., Jeon, H. -G., Jeon, S. R., Jeon, Y. R., Jeong, H. K., Jung, I. -A., Kim, H. J., Kim, J. S., Kim, J. A., Kim, K. T., Kim, M. S., Kim, S. H., Kim, Y. -I., Lee, C. S., Lee, E. H., Lee, G. H., Lee, H. Y., Lee, H. -Y., Lee, K. H., Lee, K. R., Lee, M. S., Lee, M. -Y., Lee, R. W., Lee, S. E., Lee, S. H., Lee, S., Lee, W. Y., Noh, I. K., Park, A. R., Park, B. R., Park, H. N., Park, J. H., Park, M., Park, Y., Seo, S. -Y., Shim, J., Sim, J. H., Sohn, Y. M., Son, W. S., Son, Y. S., Song, H. J., Wi, H. K., Woo, J. J., Ye, S., Yim, K. H., Yoo, K. M., Yoon, E. J., Yun, S. Y., Chawanadelert, S., Mongkolwongroj, P., Kanokphatcharakun, K., Cheewatanakornkul, S., Laksomya, T., Pattanaprichakul, S., Chantrarat, T., Rungaramsin, S., Silaruks, S., Wongcharoen, W., Siriwattana, K., Likittanasombat, K., Katekangplu, P., Boonyapisit, W., Cholsaringkarl, D., Chatlaong, B., Chattranukulchai, P., Santanakorn, Y., Hutayanon, P., Khunrong, P., Bunyapipat, T., Jai-Aue, S., Kaewsuwanna, P., Bamungpong, P., Gunaparn, S., Hongsuppinyo, S., Inphontan, R., Khattaroek, R., Khunkong, K., Kitmapawanont, U., Kongsin, C., Naratreekoon, B., Ninwaranon, S., Phangyota, J., Phrommintikul, A., Phunpinyosak, P., Pongmorakot, K., Poomiphol, S., Pornnimitthum, N., Pumprueg, S., Ratchasikaew, S., Sanit, K., Sawanyawisuth, K., Silaruks, B., Sirichai, R., Sriwichian, A., Suebjaksing, W., Sukklad, P., Suttana, T., Tangsirira, A., Thangpet, O., Tiyanon, W., Vorasettakarnkij, Y., Wisaratapong, T., Wongtheptien, W., Wutthimanop, A., Yawila, S., Altun, A., Ozdogru, I., Ozdemir, K., Yilmaz, O., Aydinlar, A., Yilmaz, M. B., Yeter, E., Ongen, Z., Cayli, M., Pekdemir, H., Ozdemir, M., Sucu, M., Sayin, T., Demir, M., Yorgun, H., Ersanli, M., Okuyan, E., Aras, D., Abdelrahman, H., Aktas, O., Alpay, D., Aras, F., Bireciklioglu, M. F., Budeyri, S., Buyukpapuc, M., Caliskan, S., Esen, M., Felekoglu, M. A., Genc, D., Ikitimur, B., Karaayvaz, E. B., Karatas, S. K., Okutucu, S., Ozcelik, E., Quisi, A., Sag, H., Sahiner, L., Sayin, B. Y., Seker, T., Alkan, D. U., Yildirim, E., Yildirim, R., Yilmaz, F., Yuksekdag, V., Vensentini, N., Ingaramo, A. C., Sambadaro, G. A., Caputi, V. F., Berman, S. G., Dragotto, P., Kleiban, A. J., Centurion, N., Giacomi, G., Guerrero, R. A. A., Conde, D., Zapata, G., Di Paola, L. A., Ramos, J. L., Dran, R. D., Egido, J., Fernandez, A. A., Fosco, M. J., Sassone, S., Sinisi, V. A., Cartasegna, L. R., Berli, M. A., Vilamajo, O. A. G., Ferroni, F., Alaguibe, E. D., D'Amelio, A. A., Arabetti, C., Arias, L., Belardi, J. A., Bergesio, L., Berli, F., Berli, M., Borchowiec, S., Buzzetti, C., Cabrini, R., Campisi, V., Cappi, A. L., Carrizo, R., Berra, F. C., Costabel, J. P., Costamagna, O. J. A., Damonte, A. A., De Urquiza, I. N., Diez, F., Eden, M. F., Fanuele, M., Voena, F. F., Torres, M. F., Funosas, C., Giacomi, M. P., Gimenez, C. H., Gurfinkel, E. P., Had, M. D. L. M., Hansen, V., Hrabar, A. D., Ingratta, M., Lopez, A., Maehara, G., Maffei, L., Martinelli, A., Martinelli, C., Matkovich, J., Mautner, B., Meirino, A., Munguia, R., Navarro, A., Novas, V., Prados, G. P., Pontoriero, J., Potito, R. N., Ricotti, C., Rodriguez, M. A., Rolandi, F., Palladino, M. E. S., Salinger, M., Sanziani, L. S., Schygiel, P. O., Sossich, A., Tinto, J. F., Tonelli, L., Tufare, A. L., Vallejo, M., Yunis, M. E., Zillo, M., Zurbrigk, F. J., Filho, D. C. S., Jaber, J., Armaganijan, D., Neto, J. F., Steffens, A., de Souza, W. K. S. B., de Souza Neto, J. D., Ribeiro, J. M., Teixeira, M. S., Rossi, P. R. F., Pires, L., Moreira, D., Jorge, J. C. M., Filho, A. M. L., Bodanese, L. C., Montera, M. W., Del Carlo, C. H., Rodrigues, T. D. R., da Costa, F. A. A., Lopes, A., Lopes, R., Araujo, G. R., Manenti, E. R. F., Saraiva, J. F. K., Braga, J. C. F., Negri, A., Souto, L., Moncada, C., Precoma, D. B., Roquette, F., Reis, G., Filho, R. A. R., Figueiredo, E. L., Botelho, R. V., Tavares, C. M. D. F., Frack, C. R. C., Saad, J. A., Finimundi, H. C., Pisani, C., Chemello, D., Martins, M. P., Franca, C. C. B., Alban, F., Rosito, G. B. A., Moraes Junior, J. B. M. X., Tumelero, R. T., Maia, L. N., de Almeida, R. S., do Carmo Borges, N. C., Ferreira, L. G. G., Agliardi, P., Gomes, J. A. O., Araujo, V., Nakazone, M. A., Barbosa, T., Barroso, S., Falchetto, E. B., Lopes, H. B., Lemos, M. A. B. T., Biazus, G., Queiroz, L. B., Camazzola, F. E., Caporale, M., Cardoso Boscato, S., Chieza, F., Chokr, M. O., Mingireanov, R. C., Goes, N. C., Correa, C., Costa, M., Ortiz, C. C., da Silva, L. S., Paulitsch, F. D. S., da Silveira, J. A., Daros, E., de Araujo, G. R., Del Monaco, M. I., Dias, C., Dias, M. A., Wainstein, A. P. D., Pizzato, P. E., Esteves, D. C., Fabri, P., Fonseca, T. F. L., Fernandes, E., Fonseca, C., Costantini, C. R. F., Ferraz, R. F., Freire, F., Gottardo, P., Guanaes, D., Guizzardi, S., Magedanz, E. H., Igansi, F., Jannuzzi, F., Junior, G., Komar, D., Lino, E. G., Lopes, D., Junior, O. L. D. S., Lustosa, E., Macagnan, A. P., Marinho, M. C., Mazzoni, M., Melo, G., Mortari, L., Mouco, O. M. C. C., Vital, C. N., Ormundo, C., Emmer, S. O., Palmegiani, E., Pavani, R., Pereira, L., Pereira, V. L., Perreira, R., Poletti, S., Fortunato, S. C. Q., Queirantes, C., Pereira, N. R., Rech, R. L., Ribeiro, S., Rodrigues, A., Roesch, H., Reichert, T. R., Santos, D., Santos, I., Santos, M., Seroqui, M. V., Silva, S., Soares, L., Spolaor, L., Stoll, C., Duda, N. T., Trama, L., Unterkircher, B., Valois, M. V., Vargas, T., Viana, T., Vicente, C., Armaganijan, L. V., Homem, R. V., Torres, L. G. V., Vila, L., Filho, F. V. G., Eggers, G., Gutierrez, C. B., Arriagada, G., Cardenas, S. P., Fernandez, B. A. J. S., Conejeros, C., Houzvic, C., Cuevas, P. M., Montecinos, H., Forero, A., Lanas, F., Gomez, M. L., Vilches, G. C., Rey, C., Astudillo, C., Aguilar, J., Campisto, Y., Lara, C., Molina, E., Oyarzon, J. M., Olguin, V., Vergara, M., Villan, C., Diaz, J. I., Cantu, R. L., Zavala, M. G. R., Jardines, R. C., Zavaleta, N. E., Umana, S. V., Rosas, E. L., Esperon, G. L., Pozas, G., Munoz, E. C., Hernandez, N. M., Rendon, A. L., Hernandez, N. G., Ibarra, M. L. R., Carrillo, L. V., Villezca, D. L., Herrera, C. H., Prieto, J. J. L., Rodriguez, R. G., Espinosa, E. V., Martinez, D. F., Barcena, J. V., Yong, R., Briones, I. R., Pons, J. L. L., Lopez, H. A., Ruiz, R. O., de la Vega, C. D., Brito, C. C., Valenzuela, E. C., Reyes-Sanchez, R., Ruiz, A. B., Flores, O. N., Gonzalez, M. B., Nava, R. A., Cerda, J. D. M., Fierro, O. F., Campos, P. F., Alfaro, T. A. A., Bellorin, S. A., Avena, R., Chavarria, M., Espinosa, I., Silva, F. F., Nava, R. H. G., Godoy, K., Felix, E. J. G., Garcia, C. L. G., Salas, L. G. G., Guajardo, P., Gonzalez, S. H., Izquierdo, T., Ortiz, M. C. M., Vasquez, D. M., Mendoza, N., Morales, J., Nikitina, N., Aybar, S. O., Ortiz, A., Macias, P. P., Perez, F., Sanchez, J. A. P., Toledano, S. P., Gonzalez, M. R., Ramos, C. R., Castro, V. R., Cardona, G. R., Cornejo, M. R., Salinas, A., Santana, G., Perez, P. S., Castaneda, A. C. T., Cortes, R. T., Lenz, K., Drexel, H., Foechterle, J., Hagn, C., Podczeck-Schweighofer, A., Huber, K., Winkler, M., Schneeweiss, B., Gegenhuber, A., Lang, W., Eichinger-Hasenauer, S., Kaserer, P., Sykora, J., Rasch, H., Pichler, M., Schaflinger, E., Strohmer, B., Breier, R., Ebner, K. -M., Eischer, L., Freihoff, F., Lischka-Lindner, A., Mark, T., Mirtl, A., Said, A., Stocklocker, C., Vogel, B., Vonbank, A., Wohrer, C., Zanolin, D., Paparella, G., Vandergoten, P., Parque, J. -L., Capiau, L., Vervoort, G., Wollaert, B., Desfontaines, P., Mairesse, G., Boussy, T., Godart, P., De Wolf, A., Voet, J., Heyse, A., Hollanders, G., Anne, W., Vercammen, J., Purnode, P., Blankoff, I., Faes, D., Balthazar, Y., Beutels, M., Marechal, P., Verstraete, S., Xhaet, O., Striekwold, H., Thoeng, J., Hermans, K., Alzand, B., Ascoop, A. -K., Banaeian, F., Barbuto, A. -M., Billiaux, A. C., Blockmans, M., Bouvy, C., Brike, C., Capiau, H., Casier, T., Bolado, A. C. Y., De Cleen, D., De Coninck, M., de Vos, M., de Weerdt, N., Delforge, M., Delvigne, M., Denie, D., Derycker, K., Deweerd, E., Dormal, F., Drieghe, S., Everaert, M., Eykerman, T., Feys, E., Ghekiere, M., Gits, F., Hellemans, S., Helvasto, L., Jacobs, C., Lips, S., Mestdagh, I., Nimmegeers, J., Piamonte, V., Pollet, P., Postolache, A., Raepers, M., Raymenants, E., Richa, J., Rombouts, H., Salembier, J., Scheurwegs, C., Semeraro, O., Simons, N., Smessaert, C., Smolders, W., Stockman, I., Tahon, S., Thyssen, V., Tincani, G., Van Durme, F., Van Lier, D., Vandekerckhove, H., Vandekerckhove, Y., Vandenbroeck, D., Vandorpe, A., Vanhalst, E., Vanhauwaert, B., Vantomme, C., Vergauwen, L., Verloove, H., Vydt, T., Weyn, T., Reichert, P., Spacek, R., Machova, V., Zidkova, E., Ludka, O., Olsr, J., Kotik, L., Plocova, K., Racz, B., Ferkl, R., Hubac, J., Kotik, I., Monhart, Z., Burianova, H., Jerabek, O., Pisova, J., Petrova, I., Dedek, V., Honkova, M., Podrazil, P., Spinar, J., Vitovec, J., Novak, M., Lastuvka, J., Durdil, V., Antonova, P., Bockova, L., Bultas, J., Chlumsky, J., Dastychova, L., Drasnar, T., Honek, J., Horejsi, M., Hubacova, V., Janska, L., Kopeckova, I., Kratochvilova, R., Krcova, E., Labrova, R., Lindourkova, A., Lipoldova, J., Lubanda, H., Ludkova, A., Mahdalikova, L., Majernikova, M., Michalik, D., Potuznik, P., Prochazkova, E., Sulc, A., Sveceny, J., Valtova, M., Zidek, M., Zika, J., Nielsen, H., Husted, S., Hintze, U., Rasmussen, S., Bremmelgaard, A., Markenvard, J., Boerger, J., Solgaard, J., Simonsen, P., Loekkegaard, T., Bruun, M., Mertz, J., Dominguez, H., Skagen, K., Egstrup, K., Ibsen, H., Raymond, I., Bang-Hansen, T., Ellervik, C., Eriksen, E., Jensen, L., Jensen, M., Leth, M., Nygaard, A., Park, J., Schou, M., Therkelsen, A., Tilma, J., Vesterager, K., Airaksinen, J., Arola, O., Koistinen, J., Nappila, H., Peltomaki, K., Rasanen, V., Vasankari, T., Galinier, M., Gottwalles, Y., Paganelli, F., Loiselet, P., Muller, J. -J., Koujan, M. B., Marquand, A., Destrac, S., Piot, O., Delarche, N., Cebron, J. -P., Boveda, S., Guenoun, M., Guedj-Meynier, D., Galley, D., Ohayon, J., Assouline, S., Zuber, M., Amarenco, P., Ellie, E., Kadouch, J., Fournier, P. -Y., Huberman, J. -P., Lemaire, M., Rodier, G., Milandre, L., Vandamme, X., Sibon, I., Neau, J. -P., Mahagne, M. H., Mielot, A., Bonnefoy, M., Churet, J. -B., Navarre, V., Sellem, F., Monniot, G., Boyes, J. -P., Doucet, B., Martelet, M., Obadia, D., Crousillat, B., Mouallem, J., Bearez, E., Nazeyrollas, P., Brugnaux, J. P., Fedorowsky, A., Casassus, F., Berneau, J. -B., Chemin, F., Falvo, N., Perron, J. -M., Poulard, J. -E., Barreau, A., Beltra, C., Corrihons, E., Decarsin, N., Dubois, B., Ducasse, E., Giry, X., Kemmel, A., Ledure, S., Lemaire, N., Robin, F., Rosolin, N., Sanchez, D., Suissa, A., Koniger, G., Purr, J., Gerbaulet, U., Kellner, B. -T., Kopf, A., Schafer, T., Zauzig, H., Riegel, P., Hohensee, H., Eissfeller, E., Eder, W., Rehling, G., Glatzel, D., Zutz, S., Heinz, G. -U., Menke, H., Pustelnik, A., Sandow, P., Ludwig, N., Wiswedel, H., Wildenauer, W., Axthelm, C., Schwarz, T., Babyesiza, A., Stuchlik, G., Zimny, H. -H., Kropp, M., Kahl, F., Caspar, A., Omankowsky, S., Lassig, T., Hartmann, H. -J., Lehmann, G., Bindig, H. -W., Hergdt, G., Reimer, D., Hauk, J., Dorsch, W., Dshabrailov, J., Michel, H., Rapp, K. -A., Vormann, R., Mayer, P., Horstmeier, U., Eissing, V., Hey, H., Leuchtgens, H., Lilienweiss, V., Kolitsch, K., Schubert, C., Lauer, H., Buchner, T., Brauer, G., Kamin, S., Muller, K., Abdel-Qader, M., Baumbach, S., Ebert, H. -H., Schwencke, C., Schellong, S., Bernhardt, P., Karolyi, L., Sievers, B., Haverkamp, W., Salbach, P., Rohnisch, J. -U., Schoen, S., Erdle, W., Mueller, T., Mueller, H., Mitrovic, V., Babjakova, Z., Bergner, K., Boehme, S., Bonin, K., Buckert, D., Busch, F., Dichristin, U., Diez, S., Fleck, A., Flint, K., Floegel, H., Fritz, C., Frommhold, R., Gehre, J., Geyer, J., Grytzmann, A., Hahn, M., Helgert, K., Hubert, K., Kirchner-Volker, K., Klein, V., Kroll, D., Krueger, A., Lehmann, R., Mann, L., Maselli, A., Menken, G., Mikes, K., Mortan, H., Nasser, N., Nicolaus, D., Plauskat, A., Pomper, L., Quietzsch, A., Ravenhorst, C., Reichelt, C., Reimer, C., Schaefer, B., Scharrer, S., Schirmer, K., Schmidt, K., Schoene, R., Schulze, J., Schuppe, M., Simon, S., Sommer, S., Spranger, K., Talkenberger, A., Tauber, K., Tetlak, A., Toennishoff, T., Voelkel-Babyesiza, R., Voigts, B., Weiser, U., Wesendorf, S., Wildenauer, S., Wolf, T., Wurziger, J., Zak, J., Zauzig, H. -D., Ziefle, S., Zincke, S., Vangel, S., Szalai, G., Merkely, B., Kancz, S., Boda, Z., Nagy, A., Laszlo, Z., Matoltsy, A., Gaszner, B., Polgar, P., Habon, T., Noori, E., Juhasz, G., Kanakaridisz, N., Szentpeteri, I., Juhasz, F., Vertes, A., Papp, A., May, Z., Ferenczi, J., Egyutt, M., Kis, E., Engelthaler, G., Szantai, G., Fulop, E., Gombos, P., Gulyas, D., Jen, P., Kiralyhazine Gyorke, E., Kovacs, M., Kovacsne Levang, S., Marianna, S., Radics, Z., Sydo, N., Szalo, R., Szilagyi, A., Sztanyik, F., Vandrus, B., Tiraferri, E., Santoro, R., Testa, S., Di Minno, G., Moia, M., Caimi, T. M., Martini, G., Tessitori, M., Cappelli, R., Poli, D., Quintavalla, R., Melone, F., Cosmi, F., Pizzini, A., Piseddu, G., Fanelli, R., Latella, C., Santi, R., Pancaldi, L., De Cristofaro, R., Palareti, G., De Blasio, A., Salerno Uriarte, J., Minetti, F., Pogliani, E. M., Lonati, L. M., Accogli, M., Ciampani, N., Malengo, S., Feola, M., Raisaro, A., Fattore, L., Grilli, P., Germini, F., Settimi, M., Alunni, M., Duranti, G., Tedeschi, L., Baglioni, G., Avanzino, G., Berardi, M., Pannacci, V., Giombolini, A., Nicoli, S., Scarponi, T., Allasia, B., Ricciarini, P., Nasorri, R., Argena, A., Bossolasco, P., Ronchini, P., Filippi, A., Tradati, F., Bulla, C., Donzelli, L., Foppa, L., Bottarelli, M. L., Tomasello, A., Mauric, A., Femiano, C., Reggio, R., Lillo, F., Mariani, A., Forcignano, F., Volpe, M., D'Avino, M., Bongiorni, M. G., Severi, S., Capucci, A., Lodigiani, C., Salomone, E., Serviddio, G., Tondo, C., Golino, P., Mazzone, C., Iacopino, S., Pengo, V., Galvani, M., Moretti, L., Ambrosino, P., Banfi, E., Biagioli, V., Bianchi, A., Boggian, G., Breschi, M., Brusorio, S., Calcagnoli, F., Campagna, G., Carpenedo, M., Ciabatta, C., Ciliberti, G., Cimmino, G., D'Arienzo, C., Di Gennaro, L., Fedele, M., Ferrini, P. M., Granzow, K., Guazzaloca, G., Guerra, F., Lo Buglio, A., Longo, S., Macellari, F., Mesolella, E., Mollica Poeta, E., Occhilupo, P., Oriana, V., Rangel, G., Salomone, L., Scaccianoce, A., Scarone, C., Segreti, L., Sottilota, G., Villani, R., Zecca, C., Ruiter, J. H., Klomps, H., Bongaerts, M., Pieterse, M. G. C., Guldener, C., Herrman, J. -P., Lochorn, G., Lucassen, A., Adriaansen, H., The, S. H. K., Nierop, P. R., Hoogslag, P. A. M., Hermans, W., Groenemeijer, B. E., Terpstra, W., Buiks, C., Boersma, L. V. A., Boersma-Slootweg, M., Bosman, F., Bosschaert, M., Bruin, S., Danse, I., De Graaf, J., de Graauw, J., Debordes, M., Dols, S., Geerlings, F., Gorrebeeck, K., Jerzewski, A., Jetten, W., Kelderman, M., Kloosterman, T., Koomen, E. M., Krikken, J., Melman, P., Mulder, R., Pronk, A., Stallinga-de Vos, A., te Kaat, J., Tonino, P., Uppelschoten, B., van de Loo, R., van der Kley, T., van Leeuwen, G., van Putten, J. J., Westerman, L., Berge, E., Sirnes, P. A., Gjertsen, E., Hole, T., Erga, K., Hallaraker, A., Skjelvan, G., Ostrem, A., Ghezai, B., Svilaas, A., Christersson, P., Oien, T., Hoegh Henrichsen, S., Berg-Johansen, J., Otterstad, J. E., Antonsen, H., Ausen, K., Claussen, H., Dominguez, I., Jekthammer, A., Lensebraaten, A. B., Nilsen, V., O'Donovan, M., Ringdalen, K., Strand, S., Korzeniak, R., Gieroba, A., Biedrzycka, M., Ogorek, M., Wozakowska-Kaplon, B., Loboz-Grudzien, K., Kosior, J., Supinski, W., Kuzniar, J., Zaluska, R., Hiczkiewicz, J., Swiatkowska-Byczynska, L., Kucharski, L., Gruchala, M., Minc, P., Olszewski, M., Kania, G., Krzciuk, M., Lajkowski, Z., Ostrowska-Pomian, B., Lewczuk, J., Zinka, E., Karczmarczyk, A., Chmielnicka-Pruszczynska, M., Trusz-Gluza, M., Opolski, G., Bronisz, M., Glanowska, G., Ruszkowski, P., Jaworska, K., Sciborski, R., Okopien, B., Kukla, P., Wozniak-Skowerska, I., Galbas, K., Cymerman, K., Jurowiecki, J., Miekus, P., Myszka, W., Mazur, S., Lysek, R., Baszak, J., Rusicka-Piekarz, T., Raczak, G., Domanska, E., Nessler, J., Lesnik, J., Ambicka, M., Andrzejewski, D., Araminowicz, J., Barszcz, A., Bartkowiak, R., Bartnik, J., Basiak, M., Bekieszczuk, E., Bernat, L., Biedrzycki, L., Biernacka, A., Blaszczyk, D., Broton, E., Brzozowski, W., Brzustowska, M., Bzymek, R., Chmielowski, A., Chojnowski, P., Cichomski, R., Cieslak, K., Cieszynska, A., Curyllo, B., Czamara, M., Danilowicz-Szymanowicz, L., Dolecka, B., Drelich, L., Dudzik-Richter, B., Dybala, T., Dziuba, M., Faron, W., Figura-Chmielewska, M., Frankiewicz, A., Gadzinski, W., Gasior, E., Gosciniecka, B., Gutknecht, P., Guziewicz, M., Jackun-Podlesna, A., Jaguszewska, G., Jankielewicz, J., Jaremczuk-Kaczmarczyk, A., Jargiello-Baszak, M., Jarzebowski, A., Jaskulska-Niedziela, E., Jaworska-Drozdowska, M., Kabat, J., Kaczmarzyk-Radka, A., Kalin, K., Kaliszczak, R., Kiliszek, M., Klata, M., Kluczewski, M., Kobielusz-Gembala, I., Kochanska, E., Kociolek, D., Kolodzinska, A., Komlo, A., Konopka, A., Korczowska, E., Kowal, E., Kowalczyk, H. K., Kremis, E., Kruczyk, D., Krzesiak-Lodyga, A., Krzyzanowski, M., Kurdzielewicz, W., Kustrzycka-Kratochwil, D., Lesniewska-Krynska, D., Leszczynski, J., Lewicka, E., Lichota, E., Lip, K., Loboz-Rudnicka, M., Luka, J., Lysek-Jozefowicz, A., Machnikowska, M., Majewska, K., Mariankowski, R., Markiewicz, A., Mazur, M., Metzgier-Gumiela, A., Miedlar, E., Mielcarek, M., Neubauer-Geryk, J., Niedek, J., Niemirycz-Makurat, A., Nowak, A., Nowak, S., Opielowska-Nowak, B., Ozgowicz, M., Pawelska-Buczen, A., Pawlik-Rak, E., Piotrowicz, R., Ptaszynski, P., Raczynska, A., Rogowski, W., Romanek, J., Romaszkiewicz, R., Rostoff, P., Roszczyk, N., Rozewska-Furmanek, D., Rychta, J., Rzyczkowska, B., Sidor, A., Skalska, J., Smichura, M., Splawski, M., Staneta, P., Staniszewska, E., Starak-Marciniak, J., Stopyra-Poczatek, M., Sukiennik-Kujawa, M., Szafranski, J., Szalecki, P., Szczepanska, A., Szkrobka, W., Szuchnik, E., Szulowska, A., Szumczyk-Muszytowska, G., Szwoch, M., Traczyk, T., Troszczynska, M., Trzcinski, G., Tybura, S., Walasik, P., Wegrzynowska, M., Wesolowska, K., Wieczorek, W., Wierzbicka, A., Wilczewski, P., Wilgat-Szecowka, M., Wojewoda, P., Wojnowski, L., Wrobel, M., Zakutynska-Kowalczyk, K., Zyczynska-Szmon, M., Eltishcheva, V., Libis, R., Tereshchenko, S., Popov, S., Kamalov, G., Belenky, D., Zateyshchikova, A., Kropacheva, E., Kolesnikova, A., Nikolaev, K., Egorova, L., Khokhlov, A., Yakupov, E., Poltavskaya, M., Zateyshchikov, D., Drapkina, O., Vishnevsky, A., Barbarash, O., Miller, O., Aleksandrova, E., Chizhov, P., Sergeev, M., Shutemova, E., Mazur, E., Zrazhevskiy, K., Novikova, T., Kostenko, V., Moiseeva, Y., Polkanova, E., Sobolev, K., Rossovskaya, M., Zubeeva, G., Shapovalova, Y., Nagibovich, O., Edin, A., Agakhanyan, A., Batalov, R., Belenkova, Y., Bitakova, F., Chugunnaya, S., Dumikyan, A., Erofeeva, S., Gorbunova, E., Gorshkova, T., Gubanov, A., Gurmach, M., Ivanova, Y., Kolesova, T., Konyushenko, D., Korneeva, O., Kropova, O., Kuchuk, P., Kungurtseva, O., Kupriyanova, T., Kurylo, B., Kuvanova, M., Lebedeva, O., Lileeva, E., Machilskaya, O., Medvedeva, T., Monako, G., Motylev, I., Nagibovich, G., Novikova, E., Orlov, Y., Osmolovskaya, Y., Ovsannikova, A., Platonov, D., Rachkova, S., Sinitsina, O., Speshilova, S., Suslova, O., Ushakov, A., Volodicheva, O., Zemlianskaia, O., Zhirov, I., Zhuravleva, E., Zotova, I., Garcia, P. A., Fernandez, M. F. L., Tercedor, L., Iparraguirre, S. T., Monserrat, P. T., Contreras, E. M., Rafecas, J. I., Carrasco, J. M., Pavia, P. G., Pajuelo, C. G., Serrano, C. M., Alonso, L. F. I., Ruiz, A. G., Klein, J. M., Juanatey, J. R. G., Esquivias, G. B., Collado, I. M., Piquero, H. P., Cuixart, C. B., Morato, M. R., Llibre, J. B. I., Vicente, C. C., Gutierrez, M. V., Gonzalo, F. E., Fernandez, C. A. A., Plana, N. D. V., Montserrat, E. E., Alia, J. J. M., Oliva, M. A. M., Sanmartin, J. I., Gonzalez, M. J., Alvarez, M. R., Melenchon, J. H., Vera, T. R., Soriano, F. R., Riesco, L. G., Macian, M. D. M., Granado, J. Q., Navarro, M. J., Sales, J. C., Perez, J. V. V., Caamano, M. V., Torres, M. F. A., Gomez, G. M., Romo, A. I., Diaz, M. A. P., Alonso, C., Alvarez, D., Alvarez, M., Amaro, M., Andere, N., Villar, J. A., Ochoa, R. A., Austria, A., Barbeira, S., Feu, E. B., Bartes, A., Munoz, V. B., Jimenez, F. J. B., Tijuan, A. B., Ramirez, J. C., Ramos, M. C., Martinez, E. C., Moreno, M. C., Corchado, G. C., Gil, M. C., Orive, M. C., Fernandez, D. C., del Misterio, M. C., Alsina, R. C., Cabrera, A. C., de Faria, J. C. P. P., Costas, S., Marco, M. I. C., Dachs, M., Lopez, C. M. D., Borras, A. D., Madariaga, A. E., Espallargas, A., Fernandez, M., Escobar, E. F., Mas, E. F., Ferrer, A., Fosch, J., Bermudez, M. G., Millan, V. G., Saenz, M. G., Garcia, C. G., Gomez, C., Perez, Y. G., Segovia, A. G., Gonzalez, P., Grigorian, L., Molina, A. G., del Val, M. C. G., Maeso, B. H., Rodriguez, E. H., Garcia, A. I., Fernandez, M. J. J., Besa, B. J., Salvadores, P. J., Bouzamayor, M. B. L., Lasuncion, I., Gort, L. E. L., Molina, M. L., Lopez, M., Rey, A. M., Guerra, J. M., Marcus, S., Vila, A. M., Mena, M. M., Mazon, P., Zurita, F. M., Millan, G., Molina, M., Alia, P. M., Montes, D., Gonzalez, M. M., Munoz, R. B. M., Palma, A. N., Figueroa, H. N. O., Ortega, V. M., Cortes, C. O., Tomera, D. O., Merchan, N. P., Ibar, I. P., Garcia, E. P., Armayor, M. P., Carasa, M. P., Prieto, I., Quintern, V., Renom, R., Diaz, L. M. R., Rios, V., Sola, L. R., Rivera, R., Robiro, X. R., Roca, M., Saumell, C. R., Rodrigo, C., Rodriguez, E., Garcia, M. R., Jimenez, S. S., Calderon, P. S., Mendez, L. S., Parra, S. S., Santolaya, C., Sanz, M. R. S., Blanco, A. S., Serralvo, E., Sierra, N., Valero, C. S., Lopez, J. S., Fontanillas, M. T., Riera, M. T., Tobajas, G., Torres, C., Marques, J. T., Pastor, M. U., Wirdby, A., Linden, J., Henriksson, K., Elmersson, M., Egilsson, A., Borjesson, U., Svard, G., Liu, B., Lindh, A., Olsson, L. -B., Gustavsson, M., Andersson, L., Benson, L., Bothin, C., Hajimirsadeghi, A., Kadir, K., Ericsson, M., Ohlsson, A., Lindvall, H., Svensson, P., Thorne, K., Handel, H., Platonov, P., Eriksson, B., Timberg, I., Romberg, K., Crisby, M., Karlsson, J. -E., Jensen, S. A., Andersson, A., Malmqvist, L., Martinsson, B., Bernsten, F., Engdahl, J., Thulin, J., Hot-Bjelac, A., Stalby, P., Aaroe, H., Ahbeck, E., Ahlmark, H., Al-Khalili, F., Bonkowski, G., Dzeletovic, S., Ekstrand, A. -B., Eriksson, G. -B., Floren, K., Grassjo, C., Hahn, S., Jaensson, P., Jansson, B., Jansson, J. -H., Kangert, R. -M., Koch, A., Kusiak, D., Lettenstrom, A., Lindberg, A., Lindholm, C. -J., Mannermyr, A., Mansson, K., Millborg, M., Nilsson, C., Ohlin, A. -M., Olofsson, A., Osberg, A., Pedersen, A., Risbecker, K., Rosenberg, K., Samuelsson, J., Shayesteh, M., Skoglund, K., Stjernberg, M., Thorsen, C., Beer, J. H., Debrunner, J., Amstutz, D., Bruegger, J., Elise, G., Grau, A., Guinand, A., Henriette, I., Saga, E., Winnik, S., Rudyk, I., Tseluyko, V., Karpenko, O., Zhurba, S., Kraiz, I., Kupnovytska, I., Serediuk, N., Mostovoy, Y., Ushakov, O., Koval, O., Kovalskyi, I., Svyshchenko, Y., Sychov, O., Stanislavchuk, M., Kraydashenko, O., Yagensky, A., Tykhonova, S., Fushtey, I., Belegai, R., Berko, G., Burdeuna, L., Chabanna, O., Daniuk, I., Ivanov, A., Kamenska, E., Kaplan, P., Khyzhnyak, O., Kizim, S., Matova, O., Medentseva, O., Mochonyi, V., Mospan, M., Nemtsova, V., Ovdiienko, T., Palamarchuk, O., Pavelko, M., Petrovskyy, R., Plevak, D., Proshak, O., Pyvovar, S., Rasputina, L., Romanenko, O., Romanova, O., Sapatyi, A., Shumakov, O., Stets, R., Todoriuk, L., Varenov, V., Chauhan, N., Goodwin, D., Saunders, P., Evans, R., Leese, J., Jhittay, P. S., Ross, A., Kainth, M. S., Pickavance, G., Mcdonnell, J., Williams, A., Gooding, T., Wagner, H., Suryani, S., Singal, A., Sircar, S., Bilas, R., Hutchinson, P., Wakeman, A., Stokes, M., Paul, N., Aziz, M., Ramesh, C., Wilson, P., Franklin, S., Fairhead, S., Thompson, J., St Joseph, V., Taylor, G., Tragen, D., Seamark, D., Paul, C., Richardson, M., Jefferies, A., Sharp, H., Jones, H., Giles, C., Page, M., Oginni, O., Aldegather, J., Wetherwell, S., Lumb, W., Evans, P., Scouller, F., Macey, N., Stipp, Y., West, R., Thurston, S., Wadeson, P., Matthews, J., Pandya, P., Gallagher, A., Railton, T., Sinha, B., Russell, D., Davies, J. A., Ainsworth, P., Jones, C. P., Weeks, P., Eden, J., Kernick, D., Murdoch, W., Lumley, L., Patel, R. P., Wong, S. W., Saigol, M., Ladha, K., Douglas, K., Cumberlidge, D. F., Bradshaw, C., Van Zon, G., Jones, K. P., Thomas, M. J., Watson, E., Sarai, B., Ahmad, N., Willcock, W., Cairns, J., Sathananthan, S., de Kare-Silver, N., Gilliland, A., Strieder, E., Howitt, A., Vishwanathan, B., Bird, N., Gray, D., Clark, M., Bisatt, J., Litchfield, J., Fisher, E., Fooks, T., Kelsall, A. R., Alborough, E., Wakeling, J., Parfitt, M., Milne, K., Rogers, S., Priyadharshan, R., Oliver, J. L., Davies, E., Abushal, S., Jacobs, M., Hutton, C., Walls, N. I., Thompson, R., Chigbo, C., Zaidi, S. M. A., Howard, M., Butter, K. C., Barrow, S., Little, H., Haq, I. U., Gibbons, L., Glencross, S., Mcleod, A. J., Poland, K., Mulholland, C., Warke, A., Conn, P., Burns, G., Smith, R. N., Lowe, S., Kamath, R., Dau, H. S., Webster, J., Hodgins, I., Vercoe, S., Roome, P. C., Pinnock, H., Patel, J. R. A., Ali, A., Hart, N., Davies, R., Stuart, E., Neden, C. A., Danielsen, M., Heath, R., Sharma, P., Galloway, S., Hawkins, C., Oliver, R., Aylward, M., Mannion, S., Braddick, M., Edwards, D., Rothwell, A. C., Sabir, A., Choudhary, F., Khalaque, S., Wilson, A., Peters, S., Coulson, W., Roberts, N., Heer, A., Coates, S., Ward, B., Jackson, D., Walton, S., Shepherd, D., Sterry, M., Wong, T., Boon, M., Bunney, R., Haria-Shah, R., Baron, R. T., Davies, S., Schatzberger, T., Hargreaves, N., Stephenson, T., Choi, H., Batson, R., Lucraft, L., Myhill, T., Estifano, S., Geatch, D., Wilkinson, J., Veale, R., Forshaw, K., Davies, T., Zaman, K., Vinson, P., Liley, C., Bandrapalli, M., Mcginty, P., Wastling, R., Mceleny, P., Beattie, A., Cooke, P., Wong, M., Gunasegaram, J., Pugsley, M., Ahmad, S., A'Court, C., Ayers, J., Bennett, J., Cartwright, S., Dobson, S., Dooldeniya, C., Flynn, A., Fox, R., Goram, J., Halpin, A., Hay, A., Jacobs, P., Jeffers, L., Lomax, L., Munro, I., Muvva, R., Nadaph, M., Powell, K., Randfield, S., Redpath, D., Reed, R., Rickenbach, M., Rogers, G., Saunders, P. B., Seamark, C., Shewring, J., Simmons, P., Simper, H., Stoddart, H., Sword, A., Thomas, N., Thomson, A., Blenkhorn, A., Singh, B., Van Gaal, W., Abhayaratna, W., Lehman, R., Roberts-Thomson, P., Kilian, J., Coulshed, D., Catanchin, A., Colquhoun, D., Kiat, H., Eccleston, D., French, J., Zimmett, L., Ayres, B., Phan, T., Blombery, P., Crimmins, D., O'Donnell, D., Choi, A., Astridge, P., Arstall, M., Jepson, N., Binnekamp, M., Lee, A., Rogers, J., Starmer, G., Carroll, P., Faunt, J., Aggarwala, A., Barry, L., Batta, C., Beveridge, R., Black, A., Bonner, M., Boys, J., Buckley, E., Campo, M., Carlton, L., Connelly, A., Conway, B., Cresp, D., Dimitri, H., Dixon, S., Dolman, M., Duroux, M., Eskandari, M., Eslick, R., Ferreira-Jardim, A., Fetahovic, T., Fitzpatrick, D., Geraghty, R., Gibbs, J., Grabek, T., Modi, M. H., Hayes, K., Hegde, M. P., Hesketh, L., Hoffmann, B., Johnson, K., Juergens, C., Kassam, I., Lawlor, V., Lehman, M., Lehman, S., Leung, D., Mackay, S., Mackenzie, M., Mccarthy, C., Mcintosh, C., Mckeon, L., Morrison, H., Mussap, C., Myers, J. -D., Nagalingam, V., Oldfield, G., O'May, V., Palmer, J., Parsons, L., Patching, K., Patching, T., Paul, V., Plotz, M., Preston, S., Rashad, H., Ratcliffe, M., Raynes, S., Rose, J., Sanders, L., Seremetkoska, M., Setio, H., Shone, S., Shrestha, P., Singh, C., Singleton, C., Stoyanov, N., Sutcliffe, S., Swaraj, K., Tarrant, J., Thompson, S., Tsay, I. M., Vorster, M., Waldman, A., Wallis, L., Wilford, E., Wong, K., Luton, R., Gupta, M., Pandey, A. S., Cheung, S., Leader, R., Beaudry, P., Ayala-Paredes, F., Berlingieri, J., Heath, J., Poirier, G., Du Preez, M., Nadeau, R., Dresser, G., Dhillon, R., Hruczkowski, T., Schweitzer, B., Coutu, B., Angaran, P., Macdonald, P., Vizel, S., Fikry, S., Parkash, R., Lavoie, A., Cha, J., Ramjattan, B., Bonet, J., Ahmad, K., Aro, L., Aves, T., Beaudry, K., Bergeron, C., Bigcanoe, J., Bignell, N., Breakwell, L., Burke, E., Carroll, L., Clarke, B., Cleveland, T., Daheb, S., Dehghani, P., Denis, I., Djaidani, Z., Dorian, P., Douglass, S., Dunnigan, J., Ewert, A., Farquhar, D., Fearon, A., Ferleyko, L., Fournier, D., Fox, B., Grenier, M. -C., Gulliver, W., Haveman, K., Hines, C., Hines, K., Jackson, A. M., Jean, C., Jethoo, G., Kahlon, R., Kelly, S., Kim, R., Korley, V., Kornder, J., Kwan, L., Largy, J., Lewis, C., Lewis, S., Mangat, I., Moor, R., Navratil, J., Neas, I., Otis, J., Otis, R., Pandey, M., Petrie, F., Pinter, A., Raines, M., Roberts, P., Robinson, M., Sas, G., Schulman, S., Snell, L., Spearson, S., Stevenson, J., Trahey, T., Wong, S., Wright, D., El-Aziz, A. A., Seif, S. K. A., El Din, M. G., El Etriby, S., Elbahry, A., El-Etreby, A., Elkhadem, M., Katta, A., Khairy, T., Mowafy, A., Nawar, M., Ohanissian, A., Reda, A., Reda, M., Salem, H., Sami, N., Samir, S., Setiha, M., Sobhy, M., Soliman, A., Taha, N., Tawfik, M., Zaatout, E., Kettles, D., Bayat, J., Siebert, H., Horak, A., Kelfkens, Y., Garda, R., Pillay, T., Guerra, M., van Zyl, L., Theron, H., Murray, A., Louw, R., Greyling, D., Mntla, P., Ueckermann, V., Loghdey, R., Ismail, S., Ahmed, F., Engelbrecht, J., Ramdass, A., Maharajh, S., Oosthuysen, W., Angel, G., Bester, C., Booysen, M., Boshoff, C., Cannon, C., Cassimjee, S., Chami, C., Conway, G., Davids, A., de Meyer, L., Du Plessis, G., Ellis, T., Henley, L., Karsten, M., Loyd, E., Marks, J., Mavhusa, L., Mostert, M., Page, A., Rikhotso, L., Salie, M., Sasto, J., Shaik, F., Skein, A., Smith, L., Tarr, G., Tau, T., van Zyl, F., Yousef, G., Agrawal, A., Nathani, M., Ibrahim, M., Esheiba, E. M., Singh, R., Naguib, A., Abu-Mahfouz, M., Al Omairi, M., Al Naeemi, A., Maruthanayagam, R., Bazargani, N., Wassef, A., Gupta, R., Khan, M., Subbaraman, B., Abdul, A., Al Mulla, A., El Bardisy, S., Haridas, P., Jadhav, S., Magdaluyo, K., Makdad, M., Maqsood, I., Mohamed, R., Sharma, N., Sharma, R., Thanzeel, M., Canosa, R., Rama, P., Blumberg, E., Garcia, J., Mullen, P., Wilson, V., Quick, A., Ferrick, K., Kutayli, W. M., Cox, M., Franco, M., Falkowski, S., Mendelson, R., Williams, M., Miller, S., Beach, S., Alfieri, A., Gutowski, T., Haque, I., Reddy, R., Ahmed, W., Delafontaine, P., Diercks, D., Theodoro, D., Remmel, K., Alberts, M., Ison, R., Noveck, H., Duffy, P., Pitta, S., Nishijima, D., Treasure, C., Asafu-Adjaye, N., Ball, K., Bartlett, M., Bentley, M., Bowers, S., Brown, A., Browne, A., Cameron-Watts, J., Canova, M., Cassidy, D., Cervellione, K., Congal, S., Depauw, J., Dickerson, A., Eley, M., Evans, L., Felpel, S., Ferdinand, K., Fielder, D., Gentry, P., Haideri, A., Hakimi, F., Harbour, T., Hartranft, E., Hawkins, B., Headlee, M., Henson, L., Herrick, C., Hicks, T., Jasinski, S., Jones, A., Jones, L., Jones, P., Karl, S., Keeling, M., Kerr, J., Knowles, P., Langdon, J., Lay, M., Lee, J. A., Lincoln, T., Malone, E., Merliss, A., Merritt, D., Minardo, J., Mooso, B., Orosco, C., Palumbo, V., Parker, M., Parrott, T., Paserchia, S., Pearl, G., Peterson, J., Pickelsimer, N., Purcell, T., Raynor, J., Raziano, S., Richard, C., Richardson, T., Robertson, C., Sage, A., Sanghera, T., Shaw, P., Shoemaker, J., Smith, K., Stephanie, B., Thatcher, A., Theobald, H., Thompson, N., Treasure, L., Tripti, T., Verdi, C., and Worthy, V.
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Registrie ,Male ,Latin Americans ,030204 cardiovascular system & hematology ,outcomes ,0302 clinical medicine ,Drug Prescription ,Retrospective Studie ,Risk Factors ,Atrial Fibrillation ,Antithrombotic ,Prospective Studies ,Registries ,030212 general & internal medicine ,Practice Patterns, Physicians' ,Stroke ,Anticoagulant ,Atrial fibrillation ,General Medicine ,Middle Aged ,Treatment Outcome ,Stroke prevention ,outcome ,Female ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,Human ,medicine.medical_specialty ,medicine.drug_class ,Clinical Investigations ,Hemorrhage ,antithrombotic treatment ,Drug Prescriptions ,03 medical and health sciences ,Internal medicine ,medicine ,Humans ,Mexico ,Aged ,Retrospective Studies ,Fibrillation ,business.industry ,Risk Factor ,Anticoagulants ,South America ,medicine.disease ,Drug Utilization ,Clinical trial ,Prospective Studie ,Latin American ,antithrombotic treatment, atrial fibrillation, Latin American, outcomes ,business - Abstract
Author(s): Jerjes-Sanchez, Carlos; Corbalan, Ramon; Barretto, Antonio CP; Luciardi, Hector L; Allu, Jagan; Illingworth, Laura; Pieper, Karen S; Kayani, Gloria; GARFIELD-AF Investigators | Abstract: BackgroundAtrial fibrillation (AF) is an important preventable cause of stroke. Anticoagulation (AC) therapy can reduce this risk. However, prescribing patterns and outcomes in patients with non-valvular AF (NVAF) from Latin American countries are poorly described.MethodsUsing data from the Global Anticoagulant Registry in the FIELD-AF (GARFIELD-AF), we examined the stroke prevention strategies and the 1-year outcomes in patients from four Latin American countries: Argentina, Brazil, Chile, and Mexico.ResultsA total of 4162 patients (2010-2014) were included in this analysis. At the time of AF diagnosis, 39.9% of patients were prescribed vitamin K antagonists (VKA) ± antiplatelet (AP) therapy, 21.8% non-VKA oral anticoagulant (NOAC) ± AP, 24.1% AP only and 14.1% no antithrombotic treatment. The proportion of moderate-high risk patients receiving no AC therapy at participating centers was highest in Mexico (46.4%) and lowest in Chile (14.3%). During 1-year follow-up, the rates of all-cause mortality, stroke/SE and major bleeding were: 5.77 (95% CI) (5.06-6.56), 1.58 (1.23-2.02), and 0.99 (0.72-1.36) and per 100 person-years, respectively, which are higher than the global rates across all countries in GARFIELD-AF. Unadjusted rates of all-cause mortality were highest in Argentina, 6.95 (5.43-8.90), and lowest in Chile, 4.01 (2.92-5.52).ConclusionsGARFIELD-AF results describes the marked variation in the baseline characteristics and patterns of antithrombotic treatments in patients with NVAF in four Latin American countries. Over one-third of patients with a moderate-to-high risk of stroke received no AC therapy, highlighting the need for improved management of patients according to national guideline. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362.
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- 2019
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9. Protective role of cytoplasmic p21Cip1/Waf1 in apoptosis of CDK4/6 inhibitor‐induced senescence in breast cancer cells
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Yuichi Iida, Mamoru Harada, Akira Koyanagi, Hitoshi Kotani, Ryosuke Tanino, and Irna Diyana Kartika
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Cyclin-Dependent Kinase Inhibitor p21 ,Senescence ,Cancer Research ,senescence ,Mice, Nude ,Apoptosis ,Breast Neoplasms ,abemaciclib ,Transfection ,Metastasis ,Mice ,chemistry.chemical_compound ,breast cancer ,Breast cancer ,ABT‐263 ,Cell Line, Tumor ,medicine ,Animals ,Humans ,Radiology, Nuclear Medicine and imaging ,Cellular Senescence ,Research Articles ,RC254-282 ,Cancer Biology ,Navitoclax ,p21 ,Chemistry ,Cyclin-Dependent Kinase 4 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,Cyclin-Dependent Kinase 6 ,Cell cycle ,medicine.disease ,Oncology ,Cell culture ,Cancer cell ,Cancer research ,Female ,Research Article - Abstract
Inhibition of CDK4/6 slows the cell cycle and induces senescence in breast cancer cells. However, senescent cancer cells promote invasion and metastasis. Several drugs reportedly target senescent cells, including ABT‐263 (navitoclax). We examined the effects of the CDK4/6 inhibitor abemaciclib and ABT‐263 on two human breast cancer cell lines. The abemaciclib and ABT‐263 combination additively decreased the viability of MDA‐MB‐231 cells, but not MCF‐7 cells. Also, the combination therapy‐induced caspase‐dependent apoptosis in MDA‐MB‐231 cells. Combination therapy with abemaciclib and ABT‐737, an ABT‐263 analog, significantly suppressed the in vivo growth of MDA‐MB‐231 with transient body‐weight loss. Given that p16Ink4a and p21Cip1/Waf1 are key factors in senescence and that both cell lines were negative for p16, the role of p21 in apoptosis of treated breast cancer cells was investigated. Although abemaciclib increased the cytoplasmic p21 level in both cell lines as a hallmark of senescence, the abemaciclib and ABT‐263 combination decreased it only in MDA‐MB‐231 cells. This decrease of p21 expression was relieved by caspase inhibition, and p21 was colocalized with caspase‐3 in the cytoplasm of MDA‐MB‐231 cells. Alternatively, small interfering RNA‐mediated knockdown of p21 rendered caspase‐3‐negative MCF‐7 cells susceptible to abemaciclib and ABT‐263, as well as TNF‐related apoptosis‐inducing ligand. Furthermore, a clinical database analysis showed that p21high breast cancer patients had a poorer prognosis compared to p21low patients. These results suggest that cytoplasmic p21 plays a protective role in apoptosis of CDK4/6 inhibitor‐induced senescent breast cancer cells., Colocalization of p21 and caspase‐3 in treated MDA‐MB‐231 breast cancer cells.
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- 2021
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10. Direct‐acting antivirals reduce the risk of tumour progression of hepatocellular carcinoma after curative treatment
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Hiroyuki Motoyama, Kohei Kotani, Atsushi Hagihara, Naoshi Odagiri, Akihiro Tamori, Ritsuzo Kozuka, Sawako Uchida-Kobayashi, Kanako Yoshida, Norifumi Kawada, Masaru Enomoto, Hideki Fujii, Hiroko Ikenaga, and Etsushi Kawamura
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hepatitis C virus ,medicine.medical_specialty ,Carcinoma, Hepatocellular ,Antiviral Agents ,肝癌 ,survival ,Gastroenterology ,Virology ,Internal medicine ,medicine ,Humans ,Stage (cooking) ,C型肝炎ウイルス ,direct-acting antivirals ,Retrospective Studies ,Hepatology ,Proportional hazards model ,business.industry ,経口治療薬 ,Liver Neoplasms ,sustained virologic response ,Hazard ratio ,Retrospective cohort study ,Hepatitis C ,Hepatitis C, Chronic ,medicine.disease ,digestive system diseases ,BCLC Stage ,Infectious Diseases ,Hepatocellular carcinoma ,Quality of Life ,肝がん ,DAA治療 ,Neoplasm Recurrence, Local ,Liver cancer ,business ,neoplasm - Abstract
研究グループは、C型肝炎ウイルスの感染がある初期の肝がん患者に対して、がんの治療後に経口治療薬(DAA)治療によりC型肝炎ウイルスを排除することで、肝がんの進行リスクを低下させることを初めて明らかにしました。さらに、肝がんの治療頻度、死亡リスクも低下させることを明らかにしました。本研究成果により、DAA治療が肝がん治療後の患者にも有益性が高いことが示されました。C型肝炎ウイルス感染症は肝がんの原因となる感染症で、DAA治療はC型肝炎ウイルスに直接作用して増殖を抑える飲み薬です。肝がんになったことのない患者にDAA治療を行うと、肝がんが発生しにくくなることが明らかとなっていますが、肝がん根治後の患者にもがんを抑える効果があるかどうかははっきりしていませんでした。今回、本研究グループは、初発で初期の肝がんを根治した患者165例を対象とし、がんの治療後にDAA治療でC型肝炎ウイルス感染症を治すことにより、肝がんの再発リスク、がんの進行リスク、がんの治療頻度、肝臓病による死亡リスクがどのように変化するか調査しました。その結果、DAA治療をした患者としなかった患者では、再発リスクはすでにいくつもの研究で報告されているのと同じく差が見られませんでした。しかし、がんの進行リスクは、DAA治療をした患者で72%も低下しました。さらに、肝臓病による死亡リスクは88%も低下し、治療頻度も1年で59%も低下しました。, Hepatocellular carcinoma (HCC) has high recurrence rates. HCC sometimes progresses from early-stage HCC (Barcelona Clinic Liver Cancer [BCLC] stage 0/A) to advanced-stage HCC after repeated recurrences and treatments. HCC progression deteriorates quality of life and prognosis. However, ......
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- 2021
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11. Annual body mass index gain and risk of hypertensive disorders of pregnancy in a subsequent pregnancy
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Sho Tano, Takafumi Ushida, Kenji Imai, Tomoko Nakano-Kobayashi, Yasuyuki Kishigami, Shigeru Yoshida, Yukako Iitani, Hiroaki Kajiyama, Fumie Kinoshita, Yoshinori Moriyama, Mamoru Yamashita, Masato Yoshihara, Hidenori Oguchi, and Tomomi Kotani
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Adult ,medicine.medical_specialty ,Science ,Weight Gain ,Article ,Body Mass Index ,Young Adult ,Medical research ,Pregnancy ,Weight management ,Odds Ratio ,medicine ,Humans ,Retrospective Studies ,Multidisciplinary ,business.industry ,Obstetrics ,Health care ,Pregnancy Outcome ,Retrospective cohort study ,Hypertension, Pregnancy-Induced ,Odds ratio ,medicine.disease ,Confidence interval ,Risk factors ,Medicine ,Female ,Subsequent pregnancy ,medicine.symptom ,business ,Body mass index ,Weight gain - Abstract
Weight gain during interpregnancy period is related to hypertensive disorders of pregnancy (HDP). However, in interpregnancy care/counseling, the unpredictability of the timing of the next conception and the difficulties in preventing age-related body weight gain must be considered while setting weight management goals. Therefore, we suggest considering the annual change in the body mass index (BMI). This study aimed to clarify the association between annual BMI changes during the interpregnancy period and HDP risk in subsequent pregnancies. A multicenter retrospective study of data from 2009 to 2019 examined the adjusted odds ratio (aOR) of HDP in subsequent pregnancies. The aORs in several annual BMI change categories were also calculated in the subgroups classified by HDP occurrence in the index pregnancy. This study included 1,746 pregnant women. A history of HDP (aOR, 16.76; 95% confidence interval [CI], 9.62 − 29.22), and annual BMI gain (aOR, 2.30; 95% CI, 1.76 − 3.01) were independent risk factors for HDP in subsequent pregnancies. An annual BMI increase of ≥ 1.0 kg/m2/year was related to HDP development in subsequent pregnancies for women without a history of HDP. This study provides data as a basis for interpregnancy care/counseling, but further research is necessary to validate our findings and confirm this relationship.
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- 2021
12. Peritoneal Dialysis-Related Peritonitis Caused by Streptococcus oralis
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Masaomi Nangaku, Yosuke Hirakawa, Yoshifumi Hamasaki, Motonobu Nakamura, Yasuhiro Oda, and Akihiro Kotani
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medicine.medical_specialty ,medicine.medical_treatment ,Cefazolin ,Ceftazidime ,Peritonitis ,030204 cardiovascular system & hematology ,Systemic inflammation ,Gastroenterology ,Peritoneal dialysis ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Oral and maxillofacial pathology ,Internal Medicine ,medicine ,Pathogen ,biology ,business.industry ,General Medicine ,medicine.disease ,biology.organism_classification ,Streptococcus oralis ,030211 gastroenterology & hepatology ,medicine.symptom ,business ,medicine.drug - Abstract
A 77-year-old man developed peritoneal dialysis-related peritonitis caused by Streptococcus oralis, a rare pathogen causing the disease. The infection, which was not controlled by one-week intraperitoneal administration of cefazolin and ceftazidime, was cured only after switching to two-week intravenous administration of cefazolin and ceftazidime. The patient had no major dental disease or recent history of dental intervention. This case suggests that S. oralis might cause peritoneal dialysis-related peritonitis with persistent systemic inflammation via an extra-oral infection route. The clinical course is discussed along with a review of the literature.
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- 2021
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13. Actual incidence of cerebral infarction after thoracic endovascular aortic repair: a magnetic resonance imaging study
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Takashi Hachiya, Naohiko Oki, Hideki Yashiro, Sohsyu Kotani, and Yoshito Inoue
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Eacts/164 ,Pulmonary and Respiratory Medicine ,Aortic arch ,Eacts/163 ,Diffusion-weighted magnetic resonance imaging ,medicine.medical_specialty ,Thoracic endovascular aortic repair ,Infarction ,Aorta, Thoracic ,Asymptomatic ,Blood Vessel Prosthesis Implantation ,Risk Factors ,Vascular ,medicine.artery ,Occlusion ,medicine ,Humans ,Stroke ,Retrospective Studies ,Aortic Aneurysm, Thoracic ,medicine.diagnostic_test ,AcademicSubjects/MED00920 ,business.industry ,Cerebral infarction ,Incidence ,Endovascular Procedures ,Magnetic resonance imaging ,Original Articles ,Cerebral Infarction ,medicine.disease ,Blood Vessel Prosthesis ,Surgery ,Diffusion Magnetic Resonance Imaging ,Treatment Outcome ,Atheroma ,cardiovascular system ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business - Abstract
OBJECTIVES The actual incidence of cerebral infarction (CI), including asymptomatic infarction, owing to thoracic endovascular aortic repair (TEVAR) has not been reported in detail. This study was performed to investigate the incidence of post-TEVAR CI by using diffusion-weighted magnetic resonance imaging (DW-MRI) and to determine the risk factors for both symptomatic and asymptomatic CI. METHODS We examined 64 patients undergoing TEVAR at our institute between April 2017 and November 2020. Aortic atheroma was graded from 1 to 5 by preoperative computed tomography. Cerebral DW-MRIs were conducted 2 days after the procedure to diagnose postoperative CI. RESULTS A total of 44 new foci were detected by post-interventional cerebral DW-MRI in 22 patients (34.4%). Only one patient developed a symptomatic stroke (1.6%), and TEVAR was successfully completed in all cases. Debranching of the aortic arch and left subclavian artery occlusion with a vascular plug was performed in 19 (29.7%) and 12 (18.8%) patients, respectively. The number of patients with proximal landing zones 0–2 was significantly higher in the CI group than in the non-CI group (68.2% vs 11.9%; P CONCLUSIONS Over one-third of the patients examined by cerebral DW-MRI after TEVAR were diagnosed with CI. High-grade atheroma and TEVAR landing in zone 0–2 were found to be positively associated with asymptomatic CI. Clinical trial registration 02-014.
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- 2021
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14. Presepsin as a predictor of septic shock in patients with urinary tract infection
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Seiji Arai, Masashi Nomura, Hiroshi Nakayama, Yoshitaka Sekine, Daisuke Oka, Kazuhiko Kotani, Takahiro Syuto, Kazuhiro Suzuki, Hiroshi Matsui, Masami Murakami, Hidekazu Koike, Yoshiyuki Miyazawa, and Yasuhiro Shibata
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Calcitonin ,Male ,medicine.medical_specialty ,Sepsis ,procalcitonin ,Urology ,Lipopolysaccharide Receptors ,Procalcitonin ,C-reactive protein ,Risk Factors ,Bacterial infections ,Internal medicine ,medicine ,Humans ,Prospective Studies ,Risk factor ,Aged ,Urinary tract infection ,biology ,business.industry ,Septic shock ,Research ,Presepsin ,Area under the curve ,Patient Acuity ,General Medicine ,Middle Aged ,medicine.disease ,Shock, Septic ,Peptide Fragments ,Systemic Inflammatory Response Syndrome ,Diseases of the genitourinary system. Urology ,Systemic inflammatory response syndrome ,Endotoxins ,Reproductive Medicine ,Urinary Tract Infections ,biology.protein ,Biomarker (medicine) ,Cytokines ,RC870-923 ,Flank pain ,business ,Biomarkers - Abstract
Background Recently, presepsin has been reported to be a useful biomarker for early diagnosis of sepsis and evaluation of prognosis in septic patients. However, few reports have evaluated its usefulness in patients with urinary tract infections (UTI). This study aimed to evaluate whether presepsin could be a valuable marker for detecting severe sepsis, and whether it could predict the therapeutic course in patients with UTI compared with markers already used: procalcitonin (PCT) and C-reactive protein (CRP). Methods From April 2014 to December 2016, a total of 50 patients with urinary tract infections admitted to Gunma university hospital were enrolled in this study. Vital signs, presepsin, PCT, CRP, white blood cell (WBC) count, causative agents of urinary-tract infections, and other data were evaluated on the enrollment, third, and fifth days. The patients were divided into two groups: with (n = 11) or without (n = 39) septic shock on the enrollment day, and with (n = 7) or without (n = 43) sepsis on the fifth day, respectively. Presepsin was evaluated as a biomarker for systemic inflammatory response syndrome (SIRS) or septic shock. Results Regarding the enrollment day, there was no significant difference of presepsin between the SIRS and non-SIRS groups (p = 0.276). The median value of presepsin (pg/mL) was significantly higher in the septic shock group (p p = 0.007). ROC curve for diagnosing septic shock indicated an area under the curve (AUC) of 0.881 for presepsin (vs. 0.690, 0.583, and 0.527 for PCT, CRP and WBC, respectively). Regarding the 5th day after admission, the median presepsin value on the enrollment day was significantly higher in the SIRS groups than in the non-SIRS groups (p = 0.006). On the other hand, PCT (≥ 2 ng/ml) on the enrollment day was an independent risk factor for SIRS. ROC curve for diagnosing sepsis on the fifth day indicated an AUC of 0.837 for PCT (vs. 0.817, 0.811, and 0.802 for presepsin, CRP, and WBC, respectively). Conclusions This study showed that presepsin may be a good marker for diagnosing septic shock based on admission data in patients with UTI.
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- 2021
15. Interleukin-31 promotes fibrosis and T helper 2 polarization in systemic sclerosis
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Kyojiro Morikawa, Kazuki M. Matsuda, Ayumi Yoshizaki, Takehiko Kitamori, Ai Kuzumi, Yuta Norimatsu, Maiko Fukayama, Yutaka Kazoe, Asako Yoshizaki-Ogawa, Yoshihide Asano, Takemichi Fukasawa, Shinichi Sato, Hirohito Kotani, Kazuma Mawatari, and Satoshi Ebata
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Male ,General Physics and Astronomy ,Autoimmunity ,medicine.disease_cause ,T-Lymphocytes, Regulatory ,Scleroderma ,Pathogenesis ,Mice ,Fibrosis ,Medicine ,Protein Isoforms ,skin and connective tissue diseases ,Skin ,Multidisciplinary ,Interleukin-13 ,biology ,integumentary system ,Interleukin ,Antibodies, Monoclonal ,Middle Aged ,STAT1 Transcription Factor ,Female ,Antibody ,Adult ,Science ,T-helper 2 cells ,General Biochemistry, Genetics and Molecular Biology ,Collagen Type I ,Article ,Immune system ,Th2 Cells ,Rheumatology ,Animals ,Humans ,Aged ,Scleroderma, Systemic ,business.industry ,Interleukin-6 ,Interleukins ,General Chemistry ,Receptors, Interleukin ,Fibroblasts ,medicine.disease ,Collagen Type I, alpha 1 Chain ,Disease Models, Animal ,Interleukin 31 ,Gene Expression Regulation ,Immunology ,biology.protein ,Interleukin-4 ,business - Abstract
Systemic sclerosis (SSc) is a chronic multisystem disorder characterized by fibrosis and autoimmunity. Interleukin (IL)-31 has been implicated in fibrosis and T helper (Th) 2 immune responses, both of which are characteristics of SSc. The exact role of IL-31 in SSc pathogenesis is unclear. Here we show the overexpression of IL-31 and IL-31 receptor A (IL-31RA) in dermal fibroblasts (DFs) from SSc patients. We elucidate the dual role of IL-31 in SSc, where IL-31 directly promotes collagen production in DFs and indirectly enhances Th2 immune responses by increasing pro-Th2 cytokine expression in DFs. Furthermore, blockade of IL-31 with anti-IL-31RA antibody significantly ameliorates fibrosis and Th2 polarization in a mouse model of SSc. Therefore, in addition to defining IL-31 as a mediator of fibrosis and Th2 immune responses in SSc, our study provides a rationale for targeting the IL-31/IL-31RA axis in the treatment of SSc., Systemic sclerosis (SSc) disease involves multisystem fibrosis and autoimmunity with limited treatment options. Here the authors demonstrate that IL-31 and IL-31RA are overexpressed in dermal fibroblasts from SSc patients and show that fibrosis and cytokine release can be reduced upon blocking of IL-31/IL-31RA.
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- 2021
16. Single-level controlled comparison of OLIF51 and percutaneous screw in lateral position versus MIS-TLIF for lumbosacral degenerative disorders: Clinical and radiologic study
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Takanori Saito, Hirohiko Tokunaga, Atsushi Ikeura, and Yoshihisa Kotani
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Adult ,medicine.medical_specialty ,Percutaneous ,Adolescent ,Lordosis ,Visual analogue scale ,Degenerative Disorder ,Bone Screws ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,Minimally Invasive Surgical Procedures ,Orthopedics and Sports Medicine ,Child ,Aged ,Aged, 80 and over ,030222 orthopedics ,Lumbar Vertebrae ,business.industry ,Middle Aged ,medicine.disease ,Lateral position ,Surgery ,Pseudarthrosis ,Spinal Fusion ,Treatment Outcome ,medicine.anatomical_structure ,Cortical bone ,Spondylolisthesis ,business ,030217 neurology & neurosurgery ,Lumbosacral joint - Abstract
We have performed minimally invasive Oblique Lateral Interbody Fusion at L5/S1 (OLIF51) and simultaneous posterior screwing in lateral position for lumbosacral disorders. This study compared the clinical and radiologic results between OLIF51 versus Minimally Invasive Transforaminal Lumbar Interbody Fusion (MIS-TLIF) in single-level fusion for lumbosacral degenerative disorders.A total of 71 patients underwent either OLIF51 (33 cases) or MIS-TLIF (38 cases) at L5/S1 spinal segment. The average age was 64 yrs (27-88). The disorders were L5 isthmic or degenerative spondylolisthesis, foraminal stenosis, pseudarthrosis and adjacent segment degeneration, and others. Using 35 mm oblique incision, OLIF51 was performed followed by posterior percutaneous fixation in same lateral position. MIS-TLIF was performed with midline 40 mm incision and modified cortical bone trajectory (CBT) screws. The operation time, estimated blood loss, JOABPEQ effectiveness rate (%), Visual Analogue Scale (VAS), fusion rate, radiologic alignment, and complications were evaluated.Average follow-up period was 25 and 31 months (12-45) in OLIF51 and MIS-TLIF, respectively. The average operation time and estimated blood loss were 165min, 62 ml and 163 min and 68 ml, respectively. The JOABPEQ effectiveness rate in OLIF51 demonstrated higher value in low back function (44% vs 17%, P 0.02). The fusion rate was 97% and 92% in OLIF51 and MIS-TLIF, respectively. The segmental lordosis was significantly larger in OLIF51 (17 vs 11 deg, P 0.01). There were no vascular or neural complications.Although two groups demonstrated the equivalent surgical invasiveness, there was the significant superiority of OLIF51 in terms of low back function over MIS-TLIF. The segmental lordosis creation was also better in OLIF51. Even in the single-level lumbosacral fusion, OLIF51 serves as the safe and viable surgical procedure with use of lateral position surgery, minimizing the residual low back dysfunction.
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- 2021
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17. Safe and persistent growth-promoting effects of vosoritide in children with achondroplasia: 2-year results from an open-label, phase 3 extension study
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Howard M. Saal, Carlos A. Bacino, Klaus Mohnike, Daniel Hoernschemeyer, Paul Harmatz, Yumiko Kotani, Julie Hoover-Fong, Jonathan Day, Frank Rutsch, Keiichi Ozono, Alice Huntsman-Labed, Joel Charrow, Rosendo Ullot Font, Elena Fisheleva, Antonio Leiva-Gea, Felipe Luna-González, Donald Basel, Natsuo Yasui, Lynda E. Polgreen, Kala Jayaram, Hiroshi Mochizuki, Ravi Savarirayan, Ignacio Ginebreda, Louise Tofts, Paul Arundel, Michael B. Bober, William R. Wilcox, Yasemin Alanay, Klane K. White, Melita Irving, Dania M Porco, and Acibadem University Dspace
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Pediatrics ,medicine.medical_specialty ,Clinical Trials and Supportive Activities ,Clinical Sciences ,Brief Communication ,Placebo ,Achondroplasia ,Growth velocity ,Double-Blind Method ,Clinical Research ,Genetics ,medicine ,Humans ,Child ,Genetics (clinical) ,Vosoritide ,Pediatric ,Genetics & Heredity ,Growth promoting ,business.industry ,Extension study ,Natriuretic Peptide, C-Type ,medicine.disease ,Endochondral bone growth ,Treatment Outcome ,6.1 Pharmaceuticals ,Open label ,business ,General Economics, Econometrics and Finance - Abstract
Author(s): Savarirayan, Ravi; Tofts, Louise; Irving, Melita; Wilcox, William R; Bacino, Carlos A; Hoover-Fong, Julie; Font, Rosendo Ullot; Harmatz, Paul; Rutsch, Frank; Bober, Michael B; Polgreen, Lynda E; Ginebreda, Ignacio; Mohnike, Klaus; Charrow, Joel; Hoernschemeyer, Daniel; Ozono, Keiichi; Alanay, Yasemin; Arundel, Paul; Kotani, Yumiko; Yasui, Natsuo; White, Klane K; Saal, Howard M; Leiva-Gea, Antonio; Luna-Gonzalez, Felipe; Mochizuki, Hiroshi; Basel, Donald; Porco, Dania M; Jayaram, Kala; Fisheleva, Elena; Huntsman-Labed, Alice; Day, Jonathan RS | Abstract: PurposeAchondroplasia is caused by pathogenic variants in the fibroblast growth factor receptor 3 gene that lead to impaired endochondral ossification. Vosoritide, an analog of C-type natriuretic peptide, stimulates endochondral bone growth and is in development for the treatment of achondroplasia. This phase 3 extension study was conducted to document the efficacy and safety of continuous, daily vosoritide treatment in children with achondroplasia, and the two-year results are reported.MethodsAfter completing at least six months of a baseline observational growth study, and 52 weeks in a double-blind, placebo-controlled study, participants were eligible to continue treatment in an open-label extension study, where all participants received vosoritide at a dose of 15.0 μg/kg/day.ResultsIn children randomized to vosoritide, annualized growth velocity increased from 4.26 cm/year at baseline to 5.39 cm/year at 52 weeks and 5.52 cm/year at week 104. In children who crossed over from placebo to vosoritide in the extension study, annualized growth velocity increased from 3.81 cm/year at week 52 to 5.43 cm/year at week 104. No new adverse effects of vosoritide were detected.ConclusionVosoritide treatment has safe and persistent growth-promoting effects in children with achondroplasia treated daily for two years.
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- 2022
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18. Comparison between dynamic whole-body FDG-PET and early-delayed imaging for the assessment of motion in focal uptake in colorectal area
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Takeshi Nii, Tomoya Kotani, Nagara Tamaki, Chisa Bamba, Taisei Kanayama, Kei Yamada, Motoki Nishimura, Yasutomo Tanada, Shimpei Akiyama, and Shigenori Matsushima
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Adenoma ,medicine.diagnostic_test ,business.industry ,Colorectal cancer ,Dynamic imaging ,Fdg uptake ,General Medicine ,medicine.disease ,Positron emission tomography ,Medicine ,Delayed imaging ,Radiology, Nuclear Medicine and imaging ,business ,Whole body ,Nuclear medicine ,Pathological - Abstract
Serial changes of focal uptake in whole-body dynamic positron emission tomography (PET) imaging were assessed and compared with those in early-delayed imaging to differentiate pathological uptake from physiological uptake in the colorectal area, based on the change in uptake shape. In 60 patients with at least 1 pathologically diagnosed colorectal cancer or adenoma, a serial 3 min dynamic whole-body PET/computed tomography imaging was performed four times around 60 min after the administration of 18F-fluorodeoxyglucose (FDG) to create a conventional (early) image by summation. Delayed imaging was performed separately at 110 min after FDG administration. High focal uptake lesions in the colorectal area were visually assessed as “changed” or “unchanged” on serial dynamic imaging and early-delayed imaging, based on the alteration in uptake shape over time. These criteria on the images were used to differentiate pathological uptake from physiological uptake. In this study, 334 lesions with high focal FDG uptake were observed. Among 73 histologically proven pathological FDG uptakes, no change was observed in 69 on serial dynamic imaging and 72 on early-delayed imaging (sensitivity of 95 vs. 99%, respectively; ns). In contrast, out of 261 physiological FDG uptakes, a change in uptake shape was seen in 159 on dynamic PET imaging and 66 on early-delayed imaging (specificity of 61 vs. 25%, respectively; p
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- 2021
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19. Impact of maternal hypertensive disorders of pregnancy on brain volumes at term-equivalent age in preterm infants: A voxel-based morphometry study
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Kenji Imai, Masahiro Hayakawa, Yoshinori Moriyama, Yoshiaki Sato, Tomomi Kotani, Hiroyuki Kidokoro, Hiroaki Kajiyama, Takafumi Ushida, Tomoko Nakano-Kobayashi, Jun Natsume, Noriyuki Nakamura, and Satoru Katsuki
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Adult ,Male ,medicine.medical_specialty ,030204 cardiovascular system & hematology ,Cohort Studies ,White matter ,03 medical and health sciences ,0302 clinical medicine ,Pregnancy ,Internal Medicine ,medicine ,Humans ,030219 obstetrics & reproductive medicine ,medicine.diagnostic_test ,Obstetrics ,business.industry ,Infant, Newborn ,Brain ,Obstetrics and Gynecology ,Gestational age ,Magnetic resonance imaging ,Hypertension, Pregnancy-Induced ,Voxel-based morphometry ,medicine.disease ,Magnetic Resonance Imaging ,medicine.anatomical_structure ,Brain size ,Gestation ,Female ,business ,Infant, Premature ,Cohort study - Abstract
Objectives Infants born to mothers with hypertensive disorders of pregnancy (HDP) reportedly have negative behavioral and neurodevelopmental outcomes. However, the effects of maternal HDP on infant brain growth have not been fully evaluated. We aimed to evaluate brain volumes and brain injury in preterm infants born to mothers with HDP using magnetic resonance (MR) imaging at term-equivalent age. Study design In this cohort study, MR imaging was performed for 94 preterm infants born before 34 weeks of gestation at Nagoya University Hospital between 2010 and 2018. Twenty infants were born to mothers with HDP and 74 to mothers without HDP. Main outcome measures Total brain volumes and regional volumetric alterations were assessed by voxel-based morphometry, and brain injury was evaluated using the Kidokoro global brain abnormality score. Developmental quotient was assessed at a corrected age of 1.5 years in 59 infants (HDP, n = 11; non-HDP, n = 48). Results No significant differences were observed in the gray and white matter volumes of the two groups (HDP: 175 ± 24 mL, 137 ± 13 mL, respectively; non-HDP: 172 ± 24 mL, 142 ± 13 mL, respectively). Additionally, no regional volumetric alterations were observed between the two groups after covariate adjustment (gestational age and infant sex). The total Kidokoro score and developmental quotient were similar in both groups. Conclusions No significant differences in the global and regional brain volumes were observed. Further research is needed to confirm our findings at different time points of MR imaging and in different populations.
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- 2021
20. Association of frailty on treatment outcomes among patients with suspected infection treated at emergency departments
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Masashi Kusanaga, Toshikazu Abe, Shigeto Ishikawa, Shigeki Kushimoto, Kazuma Yamakawa, Yuichiro Sakamoto, Atsushi Shiraishi, Seitaro Fujishima, Junichi Sasaki, Daizoh Saitoh, Yasuhiro Otomo, Akiyoshi Hagiwara, Shin Ichiro Shiraishi, Hiroshi Ogura, Toru Hifumi, Ippei Miyagawa, Yasukazu Shiino, Naoshi Takeyama, Toshihiko Mayumi, Satoshi Gando, Joji Kotani, Kohji Okamoto, and Kiyotsugu Takuma
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medicine.medical_specialty ,Adolescent ,MEDLINE ,030204 cardiovascular system & hematology ,Logistic regression ,Sepsis ,03 medical and health sciences ,0302 clinical medicine ,Japan ,Internal medicine ,medicine ,Humans ,Hospital Mortality ,Prospective Studies ,Prospective cohort study ,Geriatric Assessment ,Aged ,Frailty ,business.industry ,Mortality rate ,030208 emergency & critical care medicine ,Emergency department ,Odds ratio ,medicine.disease ,Confidence interval ,Treatment Outcome ,Emergency Medicine ,Emergency Service, Hospital ,business - Abstract
Background The clinical frailty scale (CFS) score has been validated as a predictor of adverse outcomes in community-dwelling older people. Older people are at a higher risk of sepsis and have a higher mortality rate. However, the association of frailty on outcomes in patients with sepsis has not been completely examined. Objective This study evaluated the association between CFS and outcomes in patients with sepsis. Design This was a multicenter prospective cohort substudy. Settings and participants The study included 37 emergency departments from across Japan. The patients (age ≥16 years) were included in this study if they had suspected infection at an emergency department during December 2017-February 2018. Outcome measure and analysis The primary outcome was 28-day mortality, stratified by the CFS score categories. The secondary outcomes were the duration of hospital stay, number of ICU-free days (ICUFDs) and number of ventilator-free days (VFDs). Main results A total of 917 patients were included. The median age was 79 years. The CFS score was associated with an increased risk of 28-day mortality and with a higher likelihood of long-term hospital stay and short-term VFDs and ICUFDs. Multivariate logistic regression analysis indicated that the CFS score was a predictor of 28-day mortality [odds ratio (OR), 1.26; 95% confidence interval (CI), 1.11-1.42]. Conclusions This study reported that in patients with suspected sepsis in the emergency department, frailty may be associated with poor prognosis and length of hospital stay.
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- 2021
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21. Successful Handmade Monobloc Aortomitral Valve Replacement for Extensive Aortic Root Abscess
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Yosuke Kuroko, Naoya Sakoda, Takuya Kawabata, Masanori Hirota, Takanori Suezawa, Shingo Kasahara, and Yasuhiro Kotani
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Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Monobloc ,business.industry ,medicine.medical_treatment ,medicine.disease ,Surgery ,Lesion ,Left coronary artery ,medicine.anatomical_structure ,Valve replacement ,Debridement (dental) ,medicine.artery ,cardiovascular system ,medicine ,Cardiac skeleton ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business ,Abscess ,Sinus (anatomy) - Abstract
Aortic root abscess is one of the most catastrophic complications of aortic valve endocarditis. Complete debridement is recommended regardless of the kind of infected lesion. A 37-year-old man with extensive aortic root abscess due to prosthetic aortic valve endocarditis was surgically treated. The main lesion was the aortomitral continuity extending to the commissure between the left and right coronary cusps. After debridement, the aortic annulus underneath the left coronary artery was reconstructed using a handmade aortomitral monobloc valve without aortic annuloplasty. This valve was required for the extensive root abscess of the left and noncoronary sinus to achieve complete debridement.
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- 2021
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22. Efficacy and safety associated with the infusion speed of intravenous immunoglobulin for the treatment of Kawasaki disease: a randomized controlled trial
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Takanori Yamagata, Mari Saito, Kensuke Oka, Saori Fukui, Tomoyuki Sato, Daisuke Matsubara, Yukifumi Monden, Yasuyuki Nozaki, Kenji Miyamoto, Akiko Yokomizo, Mitsuru Seki, Takaomi Minami, Yutaka Kikuchi, and Kazuhiko Kotani
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Male ,medicine.medical_specialty ,Time Factors ,Effectiveness ,Diseases of the musculoskeletal system ,Mucocutaneous Lymph Node Syndrome ,030204 cardiovascular system & hematology ,Pediatrics ,RJ1-570 ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Rheumatology ,Randomized controlled trial ,law ,White blood cell ,Internal medicine ,hemic and lymphatic diseases ,medicine ,Humans ,Immunologic Factors ,Immunology and Allergy ,Randomized study ,Child ,Infusions, Intravenous ,Adverse effect ,Intravenous immunoglobulin ,030203 arthritis & rheumatology ,IVIG ,Kawasaki disease ,business.industry ,Incidence (epidemiology) ,Immunoglobulins, Intravenous ,Infant ,medicine.disease ,Treatment Outcome ,medicine.anatomical_structure ,RC925-935 ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,Vomiting ,Female ,medicine.symptom ,Safety ,business ,Research Article ,Artery - Abstract
Background High-dose intravenous immunoglobulin (IVIG) is the mainstay of treatment for Kawasaki disease (KD). Usually, 2 g/kg of IVIG is administered over 10–24 h, depending on the institution or physician, but the association between infusion speed and effectiveness has not been reported. In this study, we evaluated the differences in efficacy and safety between two different IVIG administration speeds. Methods This was a multicenter, unblinded, randomized controlled study. Patients newly diagnosed with KD were randomized into two groups: one who received IVIG over 12 h (12H group, double speed), and one that received IVIG over 24 h (24H group, reference speed). The endpoints included the duration of fever, incidence of coronary artery abnormalities (CAAs) and of adverse events. Laboratory data were evaluated before and after IVIG administration. Results A total of 39 patients were enrolled. There was no difference between groups in fever duration after the initiation of IVIG (21 h vs. 21.5 h, p = 0.325), and no patient experienced CAAs. Two adverse events were observed in the 12H group (elevation of aspartate aminotransferase and vomiting), however no severe adverse events requiring treatments or extension of hospital stay were observed in either group. After initial IVIG administration, the change ratio of inflammatory markers, such as white blood cell counts, neutrophils, C-reactive protein, and albumin, did not show significant differences between the two groups. On the other hand, a greater increase of serum immunoglobulin G from its baseline level was observed in the 24H group compared to the 12H group (3037 ± 648 mg/dl vs. 2414 ± 248 mg/dl, p Conclusion The efficacy and safety of IVIG administered over 12 h (double speed) were similar to those administered over 24 h (reference speed). Trial registration University Hospital Medical Information Network (UMIN000014665). Registered 27 July 2014 – Prospectively registered, https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000017058
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- 2021
23. Gap between desired and self-determined roles of general practitioners: a multicentre questionnaire study in Japan
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Kazuhiko Kotani, Yusuke Sasabuchi, Hironori Yamaguchi, and Takashi Chinen
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medicine.medical_specialty ,Medicine (General) ,Palliative care ,Cancer survivors ,Primary care ,Physicians, Primary Care ,03 medical and health sciences ,0302 clinical medicine ,R5-920 ,Japan ,Survivorship curve ,General practitioners ,Neoplasms ,medicine ,Humans ,030212 general & internal medicine ,Medical diagnosis ,Physician's Role ,Questionnaire study ,Primary health care ,business.industry ,Cancer ,medicine.disease ,Care Continuum ,Cancer treatment ,030220 oncology & carcinogenesis ,Family medicine ,Family Practice ,business ,Surveys and questionnaires ,Research Article - Abstract
Background Primary care physicians have diverse responsibilities. To collaborate with cancer specialists efficiently, they should prioritise roles desired by other collaborators rather than roles based on their own beliefs. No previous studies have reported the priority of roles such clinic-based general practitioners are expected to fulfil across the cancer care continuum. This study clarified the desired roles of clinic-based general practitioners to maximise person-centred cancer care. Methods A web-based multicentre questionnaire in Japan was distributed to physicians in 2019. Physician roles within the cancer care continuum were divided into 12 categories, including prevention, diagnosis, surgery, follow-up with cancer survivors, chemotherapy, and palliative care. Responses were evaluated by the proportion of three high-priority items to determine the expected roles of clinic-based general practitioners according to responding physicians in similarly designated roles. Results Seventy-eight departments (25% of those recruited) from 49 institutions returned questionnaires. Results revealed that some physicians had lower expectations for clinic-based general practitioners to diagnose cancer, and instead expected them to provide palliative care. However, some physicians expected clinic-based general practitioners to be involved in some treatment and survivorship care, though the clinic-based general practitioners did not report the same priority. Conclusion Clinic-based general practitioners prioritised involvement in prevention, diagnoses, and palliative care across the cancer continuum, although lower expectations were placed on them than they thought. Some additional expectations of their involvement in cancer treatment and survivorship care were unanticipated by them. These gaps represent issues that should be addressed.
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- 2021
24. Proximity Proteomics Has Potential for Extracellular Vesicle Identification
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Koichi Honke, Ryusuke Kuwahara, Takanari Nakano, Haruhiko Tokuda, Yui Ida, Izumi Sato, Tsuyoshi Sato, Norihiro Kotani, Hisako Kaneda, and Takayuki Murakoshi
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Proteomics ,0301 basic medicine ,Biochemistry ,CHL1 ,Extracellular Vesicles ,Mice ,03 medical and health sciences ,Antigen ,Anion Exchange Protein 1, Erythrocyte ,medicine ,Animals ,Humans ,Membrane surface ,030102 biochemistry & molecular biology ,Chemistry ,Proteins ,Cancer ,General Chemistry ,Extracellular vesicle ,medicine.disease ,Cell biology ,030104 developmental biology ,Caspase 14 ,Cell Adhesion Molecules ,Biomarkers ,Intracellular - Abstract
Extracellular vesicles (EVs) are biomarkers and mediators of intercellular communication. In biological samples, EVs are secreted by various types of cells. The proteomic identification of proteins expressed in EVs has potential to contribute to research and clinical applications, particularly for cancer. In this study, the proximity-labeling method-based proteomic approach was used for EV identification, labeling membrane components proximal to a given molecule on the EV membrane surface. Due to the small labeling range, proteins on the surface of the same EVs are likely to be labeled by selecting a given EV surface antigen. The protein group of cancer cell-secreted EV (cEV), which abundantly expresses a close homologue of L1 (CHL1), was examined using a model mouse for lung cancer (LC). cEV-expressed proteins were identified by proteomic analysis of enzyme-mediated activation of radical sources by comparing serum EVs from wild-type and LC mice. SLC4A1 was found to be co-expressed in CHL1-expressing EVs, highlighting EVs expressing both CHL1 and SLC4A1 as candidates for cEVs. Serum EVs expressing both CHL1 and caspase 14 were significantly elevated in LC patients compared with healthy individuals. Thus, the combination of proximity labeling and proteomic analysis allows for effective EV identification.
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- 2021
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25. CIRCULATE‐Japan: Circulating tumor DNA–guided adaptive platform trials to refine adjuvant therapy for colorectal cancer
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Takayuki Yoshino, Hiroya Taniguchi, Ichiro Takemasa, Saori Mishima, Hiroki Yukami, Daisuke Kotani, Kentaro Sawada, Takeharu Yamanaka, Yoshiaki Nakamura, Hiromichi Ebi, Takeshi Kato, Masaki Mori, Hiromichi Shirasu, Alexey Aleshin, Paul Billings, Eiji Oki, and Matthew Rabinowitz
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0301 basic medicine ,Oncology ,Cancer Research ,medicine.medical_specialty ,Pyrrolidines ,Colorectal cancer ,colorectal cancer ,Capecitabine ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Double-Blind Method ,Japan ,Report ,Internal medicine ,Antineoplastic Combined Chemotherapy Protocols ,medicine ,Adjuvant therapy ,Humans ,Prospective Studies ,Prospective cohort study ,Tipiracil ,circulating tumor DNA ,adaptive clinical trial design ,trifluridine ,business.industry ,General Medicine ,medicine.disease ,Oxaliplatin ,adjuvant chemotherapy ,Clinical trial ,030104 developmental biology ,chemistry ,Chemotherapy, Adjuvant ,030220 oncology & carcinogenesis ,Colonic Neoplasms ,Biomarker (medicine) ,Neoplasm Recurrence, Local ,Colorectal Neoplasms ,business ,Thymine ,medicine.drug - Abstract
Adjuvant chemotherapy has reduced the risk of tumor recurrence and improved survival in patients with resected colorectal cancer. Potential utility of circulating tumor DNA (ctDNA) prior to and post surgery has been reported across various solid tumors. We initiated a new type of adaptive platform trials to evaluate the clinical benefits of ctDNA analysis and refine precision adjuvant therapy for resectable colorectal cancer, named CIRCULATE‐Japan including three clinical trials. The GALAXY study is a prospectively conducted large‐scale registry designed to monitor ctDNA for patients with clinical stage II to IV or recurrent colorectal cancer who can undergo complete surgical resection. The VEGA trial is a randomized phase III study designed to test whether postoperative surgery alone is noninferior to the standard therapy with capecitabine plus oxaliplatin for 3 months in patients with high‐risk stage II or low‐risk stage III colon cancer if ctDNA status is negative at week 4 after curative surgery in the GALAXY study. The ALTAIR trial is a double‐blind, phase III study designed to establish the superiority of trifluridine/tipiracil as compared with placebo in patients with resected colorectal cancer who show circulating tumor–positive status in the GALAXY study. Therefore, CIRCULATE‐Japan encompasses both “de‐escalation” and “escalation” trials for ctDNA‐negative and ‐positive patients, respectively, and helps to answer whether measuring ctDNA postoperatively has prognostic and/or predictive value. Our ctDNA‐guided adaptive platform trials will accelerate clinical development toward further precision oncology in the field of adjuvant therapy. Analysis of ctDNA status could be utilized as a predictor of risk stratification for recurrence and to monitor the effectiveness of adjuvant chemotherapy. ctDNA is a promising, noninvasive tumor biomarker that can aid in tumor monitoring throughout disease management., CIRCULATE‐Japan encompasses both “de‐escalation” and “escalation” trials for circulating tumor DNA–negative and –positive patients, respectively, and helps to answer whether measuring circulating tumor DNA postoperatively has prognostic and/or predictive value. Our circulating tumor DNA–guided adaptive platform trials will accelerate clinical development toward further precision oncology in the field of adjuvant therapy.
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- 2021
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26. Free-floating thrombus of the aorta: 3 case reports
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Naohiko Oki, Yoshito Inoue, and Sohsyu Kotani
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Aortic arch ,medicine.medical_specialty ,RD1-811 ,Case Report ,03 medical and health sciences ,0302 clinical medicine ,medicine.artery ,Ascending aorta ,medicine ,Idiopathy ,Thoracic aorta ,Common carotid artery ,cardiovascular diseases ,Thrombus ,Aorta ,Computed tomography angiography ,medicine.diagnostic_test ,business.industry ,medicine.disease ,Thrombolysis ,Surgery ,Embolic events ,Embolism ,030220 oncology & carcinogenesis ,cardiovascular system ,030211 gastroenterology & hepatology ,Surgical thrombectomy ,Free-floating thrombi ,business - Abstract
Background Idiopathic free-floating thrombus (FFT) of the aorta is a rare occurrence, but it can lead to catastrophic consequences. The initial symptoms are typically cerebral or peripheral embolisms. Surgical thrombectomy and thrombolysis are two primary treatments for FFT. Here, we report three cases of patients with idiopathic FFT in the absence of coagulopathy who were treated successfully by surgery with no recurrent thrombi or relapse of symptoms. Case presentation Case 1 involved a 72-year-old male patient with a pedunculated thrombus in the distal aortic arch. Case 2 involved a 62-year-old female patient with a cylinder thrombus in the aortic arch and left common carotid artery. Case 3 involved a 65-year-old male patient with three pedunculated thrombi in the ascending aorta, aortic arch, and left subclavian artery. None of the patients had clinical signs of coagulopathy. Pedunculated or cylinder thrombi have a greater risk of breaking off, which can produce severe peripheral embolism in contrast with intramural thrombi (73% vs. 12%). Due to the high embolism risk for each patient, conservative medical treatment by heparinization was deemed inappropriate, so each patient underwent emergency surgical thrombus removal. After surgery, each of the three patients was treated with warfarin for secondary prevention of thromboembolism. At 7-month follow-up in outpatient practice, a computed tomography (CT) scan indicated that Patient 1 had no recurrent thrombus, and the patient has been symptom-free for 11 months. At 1-month follow-up in outpatient practice, a CT scan indicated that Patient 2 had no recurrent thrombus, and the patient has been symptom-free for 8 years. At 3-week follow-up in hospital, a CT scan indicated that Patient 3 had no recurrent thrombus, but he failed to follow-up after discharge, so his follow-up status is unknown. Conclusions For a large pedunculated or cylinder thrombus located in the thoracic aorta, surgical thrombectomy should be performed. And, in surgical thrombectomy, the location of the cannulas and cross-clamp should be selected carefully according to the location of the thrombus. After surgery, anticoagulant is important to prevent recurrent idiopathic thrombi.
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- 2021
27. Real-World Evidence of the Incidence of and Risk Factors for Type 1 Diabetes Mellitus and Hypothyroidism as Immune-Related Adverse Events Associated With Programmed Cell Death-1 Inhibitors
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Masato Kotani, Nao Ichihara, Eiji Nakatani, Koki Shimada, Yoshiki Miyachi, Hiroaki Miyata, Shiori Nishimura, Norimichi Hirahara, Hiraku Kumamaru, Hiroyuki Yamamoto, and Kiyoshi Mori
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medicine.medical_specialty ,endocrine system diseases ,Endocrinology, Diabetes and Metabolism ,Programmed Cell Death 1 Receptor ,Postmarketing surveillance ,Apoptosis ,030209 endocrinology & metabolism ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,Endocrinology ,Hypothyroidism ,Japan ,Risk Factors ,Interquartile range ,Diabetes mellitus ,Internal medicine ,medicine ,Humans ,030212 general & internal medicine ,Lung cancer ,Adverse effect ,Retrospective Studies ,Type 1 diabetes ,business.industry ,Incidence ,ICD-10 ,medicine.disease ,Diabetes Mellitus, Type 1 ,Female ,business ,Cohort study - Abstract
Objective The incidence of type 1 diabetes mellitus (T1DM) and hypothyroidism as immune-related adverse events (irAEs) after programmed cell death-1 inhibitor (PD-1i) administration has not yet been sufficiently evaluated in a real clinical setting. To assess the incidence of T1DM and hypothyroidism among PD-1is and to identify the risk factors associated with hypothyroidism using a large claims database. Methods This cohort study used the Shizuoka Kokuho database in Japan from 2012 to 2018, including approximately 2.2 million people. We enrolled 695 PD-1i-treated patients. T1DM and hypothyroidism as irAEs were identified using International Classification of Diseases 10th Revision and Anatomical Therapeutic Chemical classification codes. Risk factors for hypothyroidism were explored using the multivariable Fine and Gray regression model after adjusting for age group and sex, treating death as a competing risk. Results The cumulative incidences of T1DM and hypothyroidism were 0.3% and 8.3%, respectively. We described the detailed onset timing of irAEs in patients with T1DM and hypothyroidism; hypothyroidism was observed evenly within 1 year of the PD-1i prescription. Sex and certain cancer types, such as lung and urothelial cancers, were significantly associated with subdistribution hazard ratio (sHR) (female: sHR, 2.04 [95% CI, 1.20-3.47]; lung cancer: sHR, 0.55 [95% CI, 0.32-0.95]; and urothelial carcinoma: sHR, 2.40 [95% CI, 1.05-5.49]). Conclusion The incidence of T1DM and hypothyroidism as irAEs and associated risk factors identified in this analysis were comparable to those found in previous studies. The use of a large claims database to detect irAEs, such as T1DM and hypothyroidism, may lead to safer use of PD-1is.
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- 2021
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28. An algorithm for using deep learning convolutional neural networks with three dimensional depth sensor imaging in scoliosis detection
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Toshiaki Kotani, Hiroyuki Tachi, Satoshi Kanai, Norimasa Iwasaki, Teppei Suzuki, Hideki Sudo, Yuichiro Abe, Noriaki Kawakami, Terufumi Kokabu, and Koki Uno
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Adolescent ,Mean squared error ,Correlation coefficient ,Context (language use) ,Scoliosis ,Deep learning algorithm ,Cross-validation ,Adolescent idiopathic scoliosis ,03 medical and health sciences ,Deep Learning ,0302 clinical medicine ,Japan ,Cobb angle ,Noncontact and noninvasive system ,Humans ,Medicine ,Orthopedics and Sports Medicine ,Child ,Mean absolute error ,Accuracy ,Retrospective Studies ,Convolutional neural network for regression ,030222 orthopedics ,business.industry ,Correlation coefficient analyses ,Deep learning ,CobB ,medicine.disease ,Surgery ,Neural Networks, Computer ,Neurology (clinical) ,Artificial intelligence ,business ,Algorithm ,Algorithms ,030217 neurology & neurosurgery ,Three-dimensional depth sensor - Abstract
BACKGROUND CONTEXT: Timely intervention in growing individuals, such as brace treatment, relies on early detection of adolescent idiopathic scoliosis (AIS). To this end, several screening methods have been implemented. However, these methods have limitations in predicting the Cobb angle. PURPOSE: This study aimed to evaluate the performance of a three-dimensional depth sensor imaging system with a deep learning algorithm, in predicting the Cobb angle in AIS. STUDY DESIGN: Retrospective analysis of prospectively collected, consecutive, nonrandomized series of patients at five scoliosis centers in Japan. PATIENT SAMPLE: One hundred and-sixty human subjects suspected to have AIS were included. OUTCOME MEASURES: Patient demographics, radiographic measurements, and predicted Cobb angle derived from the deep learning algorithm were the outcome measures for this study. METHODS: One hundred and sixty data files were shuffled into five datasets with 32 data files at random (dataset 1, 2, 3, 4, and 5) and five-fold cross validation was performed. The relationships between the actual and predicted Cobb angles were calculated using Pearson's correlation coefficient analyses. The prediction performances of the network models were evaluated using mean absolute error and root mean square error between the actual and predicted Cobb angles. The shuffling into five datasets and five-fold cross validation was conducted ten times. There were no study-specific biases related to conflicts of interest. RESULTS: The correlation between the actual and the mean predicted Cobb angles was 0.91. The mean absolute error and root mean square error were 4.0 degrees and 5.4 degrees, respectively. The accuracy of the mean predicted Cobb angle was 94% for identifying a Cobb angle of >= 10 degrees and 89% for that of >= 20 degrees. CONCLUSIONS: The three-dimensional depth sensor imaging system with its newly innovated convolutional neural network for regression is objective and has significant ability to predict the Cobb angle in children and adolescents. This system is expected to be used for screening scoliosis in clinics or physical examination at schools. (C) 2021 The Authors. Published by Elsevier Inc.
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- 2021
29. Frequent PIK3CA mutations in eutopic endometrium of patients with ovarian clear cell carcinoma
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Kazuto Nishio, Kazuko Sakai, Yasushi Kotani, Noriomi Matsumura, Hisamitsu Takaya, Hidekatsu Nakai, Chiho Miyagawa, Akiko Kanto, and Kosuke Murakami
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0301 basic medicine ,Adult ,Pathology ,medicine.medical_specialty ,Class I Phosphatidylinositol 3-Kinases ,DNA Mutational Analysis ,Endometriosis ,medicine.disease_cause ,Polymerase Chain Reaction ,Article ,Pathology and Forensic Medicine ,03 medical and health sciences ,Endometrium ,0302 clinical medicine ,Ovarian cancer ,Ovarian carcinoma ,medicine ,Biomarkers, Tumor ,Humans ,neoplasms ,Microdissection ,Early Detection of Cancer ,Ovarian Neoplasms ,Mutation ,business.industry ,Cancer ,Oncogenes ,Middle Aged ,medicine.disease ,Serous fluid ,030104 developmental biology ,030220 oncology & carcinogenesis ,Clear cell carcinoma ,Female ,business ,Adenocarcinoma, Clear Cell - Abstract
Recent studies have reported cancer-associated mutations in normal endometrium. Mutations in eutopic endometrium may lead to endometriosis and endometriosis-associated ovarian cancer. We investigated PIK3CA mutations (PIK3CAm) for three hotspots (E542K, E545K, H1047R) in eutopic endometrium in patients with ovarian cancer and endometriosis from formalin-fixed paraffin-embedded specimens by laser-capture microdissection and droplet digital PCR. The presence of PIK3CAm in eutopic endometrial glands with mutant allele frequency ≥ 15% were as follows: ovarian clear cell carcinoma (OCCC) with PIK3CAm in tumors, 20/300 hotspots in 11/14 cases; OCCC without PIK3CAm, 42/78 hotspots in 11/12 cases; high-grade serous ovarian carcinoma, 8/45 hotspots in 3/5 cases; and endometriotic cysts, 5/63 hotspots in 5/6 cases. These rates were more frequent than in noncancer nonendometriosis controls (7/309 hotspots in 5/17 cases). In OCCC without PIK3CAm, 7/12 (58%) cases showed multiple hotspot mutations in the same eutopic endometrial glands. In 3/54 (5.6%) cases, PIK3CAm was found in eutopic endometrial stroma. Multisampling of the OCCC tumors with PIK3CAm showed intratumor heterogeneity in three of eight cases. In two cases, PIK3CAm was detected in the stromal component of the tumor. Homogenous PIK3CAm in the epithelial component of the tumor matched the mutation in eutopic endometrial glands in only one case. Eutopic endometrial glands in ovarian cancer and endometriosis show high frequency of PIK3CAm that is not consistent with tumors, and multiple hotspot mutations are often found in the same glands. While the mutations identified in eutopic endometrium may not be driver mutations in the patient’s cancer, these are still driver mutations but this specific clone has not undergone the requisite steps for the development of cancer.
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- 2021
30. Combination therapy of capecitabine, irinotecan, oxaliplatin, and bevacizumab as a first‐line treatment for metastatic colorectal cancer: Safety lead‐in results from the QUATTRO-II study
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Kei Muro, Masahito Kotaka, Daisuke Kotani, Yoshito Komatsu, Takeharu Yamanaka, Kentaro Yamazaki, Hironaga Satake, Akihito Kawazoe, Eiji Oki, Akihito Tsuji, Hideaki Bando, Hiroya Taniguchi, Takeshi Kato, Toshiki Masuishi, and Takayuki Yoshino
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Male ,0301 basic medicine ,Oncology ,medicine.medical_specialty ,Maximum Tolerated Dose ,Organoplatinum Compounds ,Bevacizumab ,Colorectal cancer ,Phase II Studies ,Leucovorin ,Antineoplastic Agents ,Neutropenia ,Irinotecan ,Capecitabine ,03 medical and health sciences ,0302 clinical medicine ,CAPOXIRI ,Internal medicine ,Antineoplastic Combined Chemotherapy Protocols ,Humans ,Medicine ,Pharmacology (medical) ,Neoplasm Metastasis ,FOLFOXIRI ,Aged ,Pharmacology ,Dose-Response Relationship, Drug ,Metastatic colorectal cancer ,business.industry ,Middle Aged ,medicine.disease ,digestive system diseases ,Triplet ,Oxaliplatin ,030104 developmental biology ,030220 oncology & carcinogenesis ,Camptothecin ,Female ,Fluorouracil ,Colorectal Neoplasms ,business ,Febrile neutropenia ,medicine.drug - Abstract
SummaryBackground FOLFOXIRI plus bevacizumab is the first-line treatment for metastatic colorectal cancer (mCRC) but demonstrates high neutropenia incidence among Asian patients. Hence, we conducted the randomized phase II QUATTRO-II study (ClinicalTrials.gov identifier: NCT04097444; Japan Registry of Clinical Trials identifier: jRTCs041190072) to evaluate the safety and efficacy of capecitabine, oxaliplatin, and irinotecan (CAPOXIRI) combination plus bevacizumab versus FOLFOXIRI plus bevacizumab, expecting a lower incidence of neutropenia without compromising the efficacy. Methods We investigated the recommended doses (RD) of oxaliplatin and irinotecan as a safety lead-in portion of Step 1 before initiating the randomized portion as Step 2. Four dose levels of CAPOXIRI (fixed dose of capecitabine, 1600 mg/m2; escalated/de-escalated doses of oxaliplatin and irinotecan) plus bevacizumab (7.5 mg/kg) were investigated in a 3 + 3 manner. A dose level of ≤ 2/6 of dose-limiting toxicity (DLT) cases was expected as the RD. Results In Step 1, we included nine patients (three and six in levels 0 and + 1, respectively). Level 0 (irinotecan, 200 mg/m2; oxaliplatin, 100 mg/m2) did not demonstrate DLTs. In level + 1 (irinotecan, 200 mg/m2; oxaliplatin, 130 mg/m2), although one patient experienced grade 4 febrile neutropenia, no further safety concerns were observed. As a preliminary efficacy result, the objective response rate in all nine patients was 89 % (100 and 83 % in levels 0 and + 1, respectively). Conclusions The RD of CAPOXIRI plus bevacizumab was 200, 130, and 1600 mg/m2 for irinotecan, oxaliplatin, and capecitabine, respectively, and 7.5 mg/kg for bevacizumab. The randomized portion is still ongoing.
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- 2021
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31. The significance of biopsy scar excision at the time of skin- or nipple-sparing mastectomy with immediate breast reconstruction
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Yoko Maruyama, Nanae Horisawa, Shoko Sakamoto, Masaya Hattori, Ayumi Kataoka, Yuka Endo, Haruru Kotani, Daiki Takatsuka, Hiroji Iwata, Masataka Sawaki, Kayoko Sugino, Yayoi Adachi, Seiko Okumura, Akiyo Yoshimura, Yuri Ozaki, and Kazuki Nozawa
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Scar Excision ,Cancer Research ,Reconstructive surgery ,medicine.medical_specialty ,Biopsy ,Mammaplasty ,medicine.medical_treatment ,Scars ,Breast Neoplasms ,030218 nuclear medicine & medical imaging ,Cicatrix ,03 medical and health sciences ,breast cancer ,0302 clinical medicine ,Breast cancer ,neoplastic seeding ,medicine ,AcademicSubjects/MED00300 ,breast reconstruction ,Humans ,Radiology, Nuclear Medicine and imaging ,biopsy scar ,Mastectomy ,Retrospective Studies ,medicine.diagnostic_test ,business.industry ,General Medicine ,medicine.disease ,Surgery ,Oncology ,Nipples ,030220 oncology & carcinogenesis ,Original Article ,Female ,Neoplasm Recurrence, Local ,medicine.symptom ,Breast reconstruction ,business - Abstract
Background Neoplastic seeding (NS) can occur after tissue biopsy, which is a clinical issue especially in mastectomy with immediate reconstruction. This is because postoperative radiation is not usually given and local recurrence of preserved skin flap may increase. The purpose of this study is to investigate the importance of preoperative evaluation of NS and the validity of biopsy scar excision. Patients and methods We retrospectively analysed 174 cases of mastectomy with immediate breast reconstruction. The primary endpoint is the frequency of clinical and pathological NS and the secondary endpoint is the problem of excision of needle biopsy site. Results Three cases (1.7%) had preoperative clinical findings of NS. Pathological examination revealed NS in all three cases. Biopsy scars could be excised in 115 cases among 171 cases without clinical NS. Pathological NS was found in 1 of 66 (1.5%) cases of which pathological examination was performed. Biopsy scars could not be excised in the remaining 56 cases: the biopsy scar could not be identified in 41 cases, and there was concern about a decrease in flap blood flow after excision in 15 cases. In 12 of these 15 cases, the scars were close to the skin incision; excision of these scars might have triggered skin necrosis between the incision and the biopsy scar excision site. No postoperative complications were observed. Conclusions It is important to preoperatively evaluate clinical NS, and biopsy scars should be excised in clinical NS cases. Even in cases without clinical NS, biopsy scar excision should be considered. It is also important to perform a biopsy in consideration of the incision design for reconstructive surgery., It is important to evaluate clinical neoplastic seeding (NS) due to biopsy. Biopsy scars should be excised in clinical NS cases. Excision should be considered even without clinical NS.
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- 2021
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32. Pre-pregnancy serum complement C3 level is a predictor of preterm birth for pregnancies with systemic lupus erythematosus
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Eri Nakamura, Takuya Kotani, Daisuke Fujita, Kentaro Isoda, Yumiko Wada, Shigeki Makino, Youhei Fujiki, Tohru Takeuchi, and Yuri Hiramatsu
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medicine.medical_specialty ,Multivariate analysis ,Lupus nephritis ,Diseases of the musculoskeletal system ,Preconception care ,Birth rate ,03 medical and health sciences ,0302 clinical medicine ,Systemic lupus erythematosus ,Pregnancy ,Internal medicine ,medicine ,Humans ,Lupus Erythematosus, Systemic ,030212 general & internal medicine ,Retrospective Studies ,030203 arthritis & rheumatology ,Fetus ,business.industry ,Obstetrics ,Infant, Newborn ,Pregnancy Outcome ,Retrospective cohort study ,Complement C4 ,Preterm birth ,Odds ratio ,Complement C3 ,medicine.disease ,Lupus Nephritis ,Rheumatology ,Pregnancy Complications ,Serum complement 3 level ,RC925-935 ,Premature Birth ,Female ,business ,Research Article - Abstract
Background This study aimed to clarify predictors of preterm birth in pregnancy of women with systemic lupus erythematosus (SLE). We investigated the predictors of preterm birth before pregnancy from the perspective of the importance of preconception care. Methods We analysed fetal outcomes of 108 pregnancies in 74 SLE patients in a retrospective study. We compared pre-pregnancy clinical characteristics and disease activity in these women between the preterm birth and full-term birth groups to select predictive factors for preterm birth before pregnancy. Results Eighty-three of 108 pregnancies resulted in live births, of which 27 (25.0%) were preterm births. Pre-pregnancy serum complement 3 (C3) level was significantly lower in the preterm birth group (77.0 mg/dl) than the full-term birth group (87.5 mg/dl) (P = 0.029). Multivariate analysis identified history of lupus nephritis (odds ratio: 5.734, 95% CI 1.568–21.010, P = 0.008) and low C3 level (< 85 mg/dl) at pre-pregnancy (odds ratio 4.498, 95% CI 1.296–15.616, P = 0.018) as risk factors for preterm birth. The greater the number of these risk factors, the higher was the preterm birth rate (P = 0.0007). In the case of SLEDAI score ≤ 4, the preterm birth rate was higher in the pre-pregnancy low C3 group (< 85 mg/dl) (42.1%) than in the high C3 group (C3 ≥ 85 mg/dl) (14.7%) (P = 0.018). Conclusion For patients with a history of LN, treatment management focusing on pre-pregnancy serum complement levels is very important.
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- 2021
33. Postpartum alterations following inflammation in rat pregnancy: a discovery proteomic analysis
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Hiroaki Kajiyama, Charles C.T. Hindmarch, Yoshinori Moriyama, Charles H. Graham, Tiziana Cotechini, Takafumi Ushida, Tomoko Nakano-Kobayashi, Kenji Imai, and Tomomi Kotani
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Lipopolysaccharides ,Embryology ,Proteome ,Physiology ,Inflammation ,Disease ,Preeclampsia ,Endocrinology ,Pregnancy ,Animals ,Medicine ,Rats, Wistar ,Proteomic Profile ,business.industry ,Postpartum Period ,Obstetrics and Gynecology ,Cell Biology ,medicine.disease ,Blood proteins ,Rats ,Disease Models, Animal ,Reproductive Medicine ,Gestation ,Female ,medicine.symptom ,business ,Postpartum period - Abstract
Women with a history of preeclampsia have an increased risk of subsequent cardiovascular and metabolic disease. While aberrant inflammation during pregnancy is associated with the development of preeclampsia, whether maternal inflammation increases the risk of disease later in life is unclear. Using a rat model we determined whether aberrant inflammation in pregnancy alters the levels of plasma proteins associated with cardiovascular and metabolic disease risk in the postpartum period. Pregnant rats were administered lipopolysaccharide (LPS) or saline on gestational days 13.5–16.5 to induce inflammation. Non-pregnant controls consisted of age-matched female rats subjected to similar administration of LPS or saline. Examination of the proteomic profile of plasma collected 16 weeks after delivery or from non-pregnant controls using liquid chromatography-tandem mass spectrometry revealed 100 differentially expressed proteins. Moreover, we identified 188 proteins in pregnant rats, of which 49 were differentially expressed in saline- vs LPS-treated dams. Of the 49 proteins regulated by LPS, 28 were pregnancy specific. PANTHER classification software, DAVID database and Ingenuity Pathways analysis revealed that the differentially expressed proteins in pregnant saline vs LPS-treated rats are associated with alterations in lipid and glucose metabolism and atherosclerosis, all of which may contribute to cardiovascular and metabolic disease risk. Results from proteomic and pathway analyses were validated by immunoassay of three serum proteins selected a priori and by assessment of serum metabolites. This discovery study demonstrates that aberrant inflammation during pregnancy results in long-lasting postpartum physiological alterations known to be associated with metabolic and cardiovascular disease.
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- 2021
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34. A Low Tumor Mutational Burden and PTEN Mutations Are Predictors of a Negative Response to PD-1 Blockade in MSI-H/dMMR Gastrointestinal Tumors
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Yasutoshi Kuboki, Masahito Kawazu, Takeshi Kuwata, Takayuki Yoshino, Masafumi Ikeda, Takashi Kojima, Hiroyuki Mano, Itaru Endo, Yoshiaki Nakamura, Keigo Chida, Kohei Shitara, Hiroya Taniguchi, Toshihiro Suzuki, Akihito Kawazoe, Daisuke Kotani, Toshihide Ueno, and Tetsuya Nakatsura
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0301 basic medicine ,Cancer Research ,biology ,Colorectal cancer ,business.industry ,Cancer ,medicine.disease ,Blockade ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,Oncology ,030220 oncology & carcinogenesis ,Pancreatic cancer ,medicine ,Cancer research ,biology.protein ,PTEN ,Immunohistochemistry ,Duodenal cancer ,business ,Small intestine cancer - Abstract
Purpose: This study performed a comprehensive molecular characterization of microsatellite instability–high (MSI-H)/mismatch repair–deficient (dMMR) gastrointestinal (GI) tumors to elucidate predictors of response to PD-1 blockade. Experimental Design: Forty-five patients with MSI-H/dMMR GI tumors, including gastric cancer, colorectal cancer, cholangiocarcinoma, small intestine cancer, pancreatic cancer, and duodenal cancer, receiving PD-1 blockade were analyzed. We conducted the genomic profiling of GI tumors by whole-exome sequencing or targeted next-generation sequencing. The tumor microenvironment was evaluated by transcriptomic analysis and multiplex fluorescence IHC. Results: Patients with low tumor mutational burdens (TMBs) had lower objective response rates (ORRs; 0% vs. 48.8%) and a significantly shorter progression-free survival (PFS; 2.3 vs. 15.6 months; HR, 6.20; P = 0.002) than those with high TMBs. Among common gene alterations in GI tumors, only PTEN mutations, which were mutually exclusive with a low TMB, were significantly associated with a lower ORRs than wild-type PTEN (21.4 vs. 54.8%; odds, 4.45; P = 0.045). Compared with wild-type PTEN, PTEN mutations in the phosphatase domain were associated with significantly lower ORRs (12.5 vs. 54.8%; P = 0.049), shorter PFS (2.6 vs. 15.6 months; HR, 5.04; P < 0.001), lower intratumoral CD8+ T-cell levels, higher intratumoral CD204+ macrophage levels, and PI3K/AKT/mTOR pathway enrichment, whereas PTEN mutations in the C2 domain were not. Conclusions: Low TMBs and PTEN mutations, especially mutations in the phosphatase domain associated with an immunosuppressive environment, were mutually exclusive and might be negative predictors of PD-1 blockade responses in patients with MSI-H/dMMR GI tumors.
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- 2021
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35. A multicenter retrospective study of the esophageal triamcinolone acetonide-filling method in patients with extensive esophageal endoscopic submucosal dissection
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Hironobu Mikami, Norihisa Ishimura, Takafumi Yuki, Satoshi Kotani, Nobuhiko Fukuba, Yusuke Takahashi, Kotaro Shibagaki, Noritsugu Yamashita, Masahito Aimi, Shunji Ishihara, and Daisuke Izumi
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medicine.medical_specialty ,Triamcinolone acetonide ,Endoscopic Mucosal Resection ,Esophageal Neoplasms ,business.industry ,Gastroenterology ,Retrospective cohort study ,Endoscopic submucosal dissection ,Esophageal cancer ,medicine.disease ,Triamcinolone Acetonide ,humanities ,Surgery ,Stenosis ,Steroid therapy ,Esophageal stenosis ,Esophageal Stenosis ,medicine ,Humans ,In patient ,business ,Retrospective Studies ,medicine.drug - Abstract
Endoscopic submucosal dissection (ESD) for extensive esophageal cancer is sometimes associated with post-ESD stenosis, despite preventative steroid therapy. In this retrospective multicenter analysis, we evaluated the factors associated with therapy resistance.We enrolled 73 patients with 75 extensive esophageal cancers treated with ESD. Stenosis prevention was performed using two esophageal triamcinolone acetonide (TA)-fillings, and repeated if stenosis was found on follow-up. Therapy-resistance factors associated with incidence of severe stenosis requiring endoscopic balloon dilation (EBD) were evaluated, including age, gender, previous treatment history, tumor location, morphology, resection size, histologic type, invasion depth, and horizontal resection grade (HR-grade 1, ≥ 9/12 and10/12 of the circumference; grade 2, ≥ 10/12 and11/12; grade 3, ≥ 11/12 but not circumferential; and grade 4, entirely circumferential).Severe stenosis occurred in 17.3%(13/75) of cases, with a median of two EBDs (range, 1-6 times). Severe stenosis was significantly associated with HR-grade elevation and previous treatment history (Esophageal TA-filling is a promising stenosis-preventive steroid therapy, even in entirely circumferential ESD cases. However, HR-grade 2 or more elevation and previous treatment history were independently associated with therapy resistance.
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- 2021
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36. Development of a prediction model of treatment response in patients with cutaneous arteritis: Insights from a cohort of 33 patients
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Maiko Fukayama, Asako Yoshizaki-Ogawa, Kazuki M. Matsuda, Takemichi Fukasawa, Ayumi Yoshizaki, Satoshi Ebata, Hirohito Kotani, Ai Kuzumi, and Shinichi Sato
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Male ,Vasculitis ,medicine.medical_specialty ,Prednisolone ,Azathioprine ,Dermatology ,Clinical prediction rule ,Logistic regression ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Humans ,Medicine ,Arteritis ,Retrospective Studies ,Skin ,Receiver operating characteristic ,business.industry ,General Medicine ,medicine.disease ,Confidence interval ,Polyarteritis Nodosa ,030220 oncology & carcinogenesis ,business ,medicine.drug - Abstract
Cutaneous arteritis (CA) is necrotizing vasculitis invading the small- to medium-sized arteries of the skin. The majority of patients can be favorably managed by low- to medium-dose systemic corticosteroids (prednisolone
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- 2021
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37. Antenatal prediction models for short‐ and medium‐term outcomes in preterm infants
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Yumiko Kobayashi, Yoshinori Moriyama, Tomoko Nakano-Kobayashi, Hiroaki Kajiyama, Masahiro Nakatochi, Noriyuki Nakamura, Masahiro Hayakawa, Takafumi Ushida, Kenji Imai, and Tomomi Kotani
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Pediatrics ,medicine.medical_specialty ,Population ,Risk management tools ,Infant, Premature, Diseases ,Cerebral palsy ,03 medical and health sciences ,0302 clinical medicine ,Pregnancy ,Intensive Care Units, Neonatal ,Diagnosis ,medicine ,Humans ,030212 general & internal medicine ,education ,education.field_of_study ,030219 obstetrics & reproductive medicine ,Periventricular leukomalacia ,Receiver operating characteristic ,business.industry ,Infant, Newborn ,Obstetrics and Gynecology ,Prenatal Care ,General Medicine ,Stepwise regression ,medicine.disease ,Outcome and Process Assessment, Health Care ,Intraventricular hemorrhage ,Infant, Extremely Premature ,Apgar Score ,Premature Birth ,Gestation ,Female ,business ,Infant, Premature - Abstract
INTRODUCTION In extremely and very preterm infants, predicting individual risks for adverse outcomes antenatally is challenging but necessary for risk-stratified perinatal management and parents' participation in decision-making about treatment. Our aim was to develop and validate prediction models for short-term (neonatal period) and medium-term (3 years of age) outcomes based on antenatal maternal and fetal factors alone. MATERIAL AND METHODS A population-based study was conducted on 31 157 neonates weighing ≤1500 g and born between 22 and 31 weeks of gestation registered in the Neonatal Research Network of Japan during 2006-2015. Short-term outcomes were assessed in 31 157 infants and medium-term outcomes were assessed in 13 751 infants among the 31 157 infants. The clinical data were randomly divided into training and validation data sets in a ratio of 2:1. The prediction models were developed by factors selected using stepwise logistic regression from 12 antenatal maternal and fetal factors with the training data set. The number of factors incorporated into the model varied from 3 to 10, on the basis of each outcome. To evaluate predictive performance, the area under the receiver operating characteristics curve (AUROC) was calculated for each outcome with the validation data set. RESULTS Among short-term outcomes, AUROCs for in-hospital death, chronic lung disease, intraventricular hemorrhage (grade III or IV) and periventricular leukomalacia were 0.85 (95% CI 0.83-0.86), 0.80 (95% CI 0.79-0.81), 0.78 (95% CI 0.75-0.80), and 0.58 (95% CI 0.55-0.61), respectively. Among medium-term outcomes, AUROCs for cerebral palsy and developmental quotient of
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- 2021
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38. Maternal low birth weight and hypertensive disorders of pregnancy
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Tomoko Nakano-Kobayashi, Noriyuki Nakamura, Mamoru Yamashita, Takafumi Ushida, Kenji Imai, Shigeru Yoshida, Hiroaki Kajiyama, Fumie Kinoshita, Yoshinori Moriyama, and Tomomi Kotani
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Adult ,medicine.medical_specialty ,Birth weight ,Mothers ,030204 cardiovascular system & hematology ,Risk Assessment ,Preeclampsia ,03 medical and health sciences ,Maternity care ,0302 clinical medicine ,Pregnancy ,Internal Medicine ,Birth Weight ,Humans ,Medicine ,Risk factor ,Retrospective Studies ,030219 obstetrics & reproductive medicine ,business.industry ,Obstetrics ,Obstetrics and Gynecology ,Retrospective cohort study ,Hypertension, Pregnancy-Induced ,medicine.disease ,Low birth weight ,Lifestyle factors ,Female ,medicine.symptom ,business - Abstract
Objectives: To investigate the association between maternal own low birth weight (
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- 2021
39. Lenvatinib-Induced Tumor-Related Hemorrhages in Patients with Large Hepatocellular Carcinomas
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Yukio Miki, Kohei Kotani, Kanako Yoshida, Kenjiro Kimura, Naoshi Odagiri, Sawako Uchida-Kobayashi, Akihiro Tamori, Hiroko Ikenaga, Shoji Kubo, Atsushi Hagihara, Ken Kageyama, Masaru Enomoto, Norifumi Kawada, Akira Yamamoto, and Hideki Fujii
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Male ,Cancer Research ,Necrosis ,Computed Tomography Angiography ,Hepatocellular carcinoma ,Tyrosine kinase inhibitor ,Gastroenterology ,Tyrosine-kinase inhibitor ,chemistry.chemical_compound ,0302 clinical medicine ,030212 general & internal medicine ,Aged, 80 and over ,Liver Neoplasms ,General Medicine ,Middle Aged ,Treatment Outcome ,Oncology ,030220 oncology & carcinogenesis ,Quinolines ,Female ,medicine.symptom ,Lenvatinib ,medicine.medical_specialty ,Carcinoma, Hepatocellular ,medicine.drug_class ,肝細胞癌 ,Antineoplastic Agents ,Hemorrhage ,レンバチニブ ,03 medical and health sciences ,Internal medicine ,medicine ,Humans ,In patient ,Dosing ,Adverse effect ,Protein Kinase Inhibitors ,Aged ,Retrospective Studies ,Vascular lake phenomenon ,business.industry ,Phenylurea Compounds ,Blood flow ,medicine.disease ,digestive system diseases ,chemistry ,肝がん ,business - Abstract
Introduction: Lenvatinib has been approved as a systemic therapy for patients with unresectable hepatocellular carcinoma (HCC). We recently experienced lenvatinib-induced tumor-related hemorrhage in patients with HCC. The full details of tumor-related hemorrhage as a lenvatinib-related adverse event have not been elucidated. Methods: This was a retrospective single-center study that enrolled consecutive patients treated with lenvatinib for unresectable HCC from April 2018 to February 2020. Results: Sixty-eight consecutive patients were enrolled in this study. Among them, 5 cases developed intraperitoneal or intratumoral hemorrhages. The patients with hemorrhage had larger tumors (maximum tumor size, 97.5 ± 46.4 and 38.2 ± 28.8 mm, respectively; p = 0.009) than the patients without hemorrhage. The dosing period of lenvatinib (median, 3 and 93 days, respectively; p < 0.001) and the survival time from initial administration of lenvatinib (median, 77 and 495 days, respectively; p < 0.001) of the patients with hemorrhage were shorter than those of the patients without hemorrhage. Especially, in 4 cases with large HCCs (maximum tumor diameter was >90 mm), tumor hemorrhage with vascular lake-like phenomenon was evident, although most tumor blood flow was suppressed. Discussion/Conclusion: It becomes clear that lenvatinib treatment brings about tumor-related hemorrhages despite rapid suppression of tumor blood flow. We speculate that lenvatinib quickly blocks the feeding circulation, resulting in tumor hemorrhage by necrosis. Clinicians should pay careful attention to the development of life-threatening hemorrhages when treating large HCCs with lenvatinib.
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- 2021
40. A case report of bladder and intestinal endometriosis, and the relationship between sex hormone receptor expression and PIK3CA mutation analysis
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Noriomi Matsumura, Chiho Miyagawa, Akiko Kanto, Kosuke Murakami, Yasushi Kotani, and Hidekatsu Nakai
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Adult ,medicine.medical_specialty ,Class I Phosphatidylinositol 3-Kinases ,medicine.medical_treatment ,Endometriosis ,Estrogen receptor ,Case Report ,PIK3CA mutation ,Gastroenterology ,lcsh:Gynecology and obstetrics ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Positron Emission Tomography Computed Tomography ,Internal medicine ,Biopsy ,Progesterone receptor ,medicine ,Humans ,030212 general & internal medicine ,Progesterone resistance ,lcsh:RG1-991 ,030219 obstetrics & reproductive medicine ,medicine.diagnostic_test ,business.industry ,lcsh:Public aspects of medicine ,Urinary Bladder Diseases ,Obstetrics and Gynecology ,Sigmoid colon ,lcsh:RA1-1270 ,General Medicine ,Sex hormone receptor ,medicine.disease ,medicine.anatomical_structure ,Reproductive Medicine ,Dienogest ,chemistry ,Female ,Hormone therapy ,business - Abstract
Background Extragonadal endometriosis is a rare condition, and its disease manifestation and long-term prognosis have not been elucidated. We report an extragonadal endometriosis case controlled by drug therapy for 14 years with analysis of the sex hormone receptor expression and PIK3CA mutation. Case presentation The patient was diagnosed with bladder endometriosis at age of 30 years, and underwent bilateral nephrostomy and GnRHa therapy with add-back therapy. The patient was switched to dienogest therapy at age 35 and had hematuria and bloody stools at age 38. PET-CT revealed a 6-cm mass in the bladder with fluorodeoxyglucose accumulation and the diagnosis of endometriosis in the bladder, sigmoid colon, and cecum was confirmed after the biopsy result. The lesion’s tubular structures were positive for the estrogen receptor, but only 30% positive for the progesterone receptor, and the H1047R mutation in PIK3CA was found in tubular structures of the bladder lesion. GnRHa therapy caused the tumors to shrink. Conclusion Decreased progesterone receptor expression and oncogenic mutations may influence the course of less common and rare site endometriosis. Rare site endometriosis often requires long-term hormone therapy, and management should be tailored to the patient's life stage, keeping in mind complications, such as decreased bone density.
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- 2021
41. Usefulness of lactate dehydrogenase in differentiating abnormal cervical lymphadenopathy
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Kazuhiko Kotani, Naoko Kamiya, Yukiko Ishikawa, Yuka Sagara, Taro Takeshima, Sayaka Yamamoto, Masami Matsumura, and Makiko Mieno
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medicine.medical_specialty ,Mononucleosis ,diagnosis ,Logistic regression ,01 natural sciences ,03 medical and health sciences ,0302 clinical medicine ,Cervical lymphadenopathy ,Internal medicine ,Internal Medicine ,medicine ,030212 general & internal medicine ,0101 mathematics ,Lymph node ,lcsh:R5-920 ,business.industry ,010102 general mathematics ,cervical lymphadenopathy ,lactate dehydrogenase ,Odds ratio ,Original Articles ,lymph node ,medicine.disease ,Confidence interval ,Tuberculous lymphadenitis ,medicine.anatomical_structure ,Etiology ,Original Article ,Geriatrics and Gerontology ,medicine.symptom ,Family Practice ,business ,lcsh:Medicine (General) - Abstract
Background Cervical lymphadenopathy is commonly seen in general practice, and its etiology is diverse. Establishing the diagnostic strategy for lymphadenopathy would be desirable to avoid overlooking neoplasms or other critical conditions. This study aims to identify the useful laboratory parameters for cervical lymphadenopathy that require clinical observation or intervention. Methods The participants were outpatients presenting cervical swelling or cervical lymph node (LN) pain who consulted the General Internal Medicine department from 2010 to 2016. We evaluated the characteristics, physical findings, and laboratory parameters with final diagnoses by multivariate logistic regression analysis. We categorized the final diagnoses as “Clinical Intervention Required Group (CIRG)” including necrotizing lymphadenitis, hematologic neoplasms, metastatic lymphadenopathy, tuberculous lymphadenitis, bacterial infectious diseases, infectious mononucleosis, autoimmune diseases, and other abnormal conditions or “No‐CIRG” not requiring further clinical observation or intervention. Results We evaluated 409 participants, with 130 (31.8%) diagnosed as belonging to the CIRG. There was an association between CIRG and various parameters: age ≥60 years old (adjusted odds ratio [AOR], 2.70; 95% confidence interval [CI], 1.48‐4.90), having a referral (AOR, 1.83; 95% CI, 1.12‐3.00), diameter of LN ≥ 2 cm (AOR, 1.91; 95% CI, 1.05‐3.48), fixed LNs (AOR, 2.74; 95% CI, 1.02‐7.37), and lactate dehydrogenase (LD) ≥400 U/L (AOR, 3.78; 95% CI, 1.46‐9.77). Eighty‐two percent of LD ≥ 400 cases in the CIRG were infectious mononucleosis or necrotizing lymphadenitis. Conclusions Besides the clinical indicators reported previously, we may apply an elevated LD level as a useful indicator of cervical lymphadenopathy that requires further clinical observation or intervention., We evaluated 409 participants presenting cervical swelling or cervical lymph node pain to identify useful physical findings or laboratory parameters for cervical lymphadenopathy that require clinical observation or intervention. The risk factors associated with that by multivariate analysis were age ≥60 years, having a referral, diameter of cervical LN ≥2 cm, fixed cervical LNs, and LD ≥400 U/L.
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- 2021
42. Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry
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Jitendra PS. Sawhney, Veerappa A. Kothiwale, Vikas Bisne, Rajashekhar Durgaprasad, Praveen Jadhav, Manoj Chopda, Velam Vanajakshamma, Ramdhan Meena, Govindan Vijayaraghavan, Kamaldeep Chawla, Jagan Allu, Karen S. Pieper, A. John Camm, Ajay K. Kakkar, Jean-Pierre Bassand, David A. Fitzmaurice, Samuel Z. Goldhaber, Shinya Goto, Sylvia Haas, Werner Hacke, Lorenzo G. Mantovani, Frank Misselwitz, Alexander G.G. Turpie, Martin van Eickels, Freek W.A. Verheugt, Gloria Kayani, Keith A.A. Fox, Bernard J. Gersh, Hector Lucas Luciardi, Harry Gibbs, Marianne Brodmann, Frank Cools, Antonio Carlos Pereira Barretto, Stuart J. Connolly, Alex Spyropoulos, John Eikelboom, Ramon Corbalan, Dayi Hu, Petr Jansky, Jørn Dalsgaard Nielsen, Hany Ragy, Pekka Raatikainen, Jean-Yves Le Heuzey, Harald Darius, Matyas Keltai, Sanjay Kakkar, Jitendra Pal Singh Sawhney, Giancarlo Agnelli, Giuseppe Ambrosio, Yukihiro Koretsune, Carlos Jerjes Sánchez Díaz, Hugo Ten Cate, Dan Atar, Janina Stepinska, Elizaveta Panchenko, Toon Wei Lim, Barry Jacobson, Seil Oh, Xavier Viñolas, Marten Rosenqvist, Jan Steffel, Pantep Angchaisuksiri, Ali Oto, Alex Parkhomenko, Wael Al Mahmeed, David Fitzmaurice, D.Y. Hu, K.N. Chen, Y.S. Zhao, H.Q. Zhang, J.Z. Chen, S.P. Cao, D.W. Wang, Y.J. Yang, W.H. Li, Y.H. Yin, G.Z. Tao, P. Yang, Y.M. Chen, S.H. He, Ying Wang, Yong Wang, G.S. Fu, X. Li, T.G. Wu, X.S. Cheng, X.W. Yan, R.P. Zhao, M.S. Chen, L.G. Xiong, P. Chen, Y. Jiao, Y. Guo, L. Xue, F.Z. Wang, H. Li, Z.M. Yang, C.L. Bai, J. Chen, J.Y. Chen, X. Chen, S. Feng, Q.H. Fu, X.J. Gao, W.N. Guo, R.H. He, X.A. He, X.S. Hu, X.F. Huang, B. Li, J. Li, L. Li, Y.H. Li, T.T. Liu, W.L. Liu, Y.Y. Liu, Z.C. Lu, X.L. Luo, T.Y. Ma, J.Q. Peng, X. Sheng, X.J. Shi, Y.H. Sun, G. Tian, K. Wang, L. Wang, R.N. Wu, Q. Xie, R.Y. Xu, J.S. Yang, L.L. Yang, Q. Yang, Y. Ye, H.Y. Yu, J.H. Yu, T. Yu, H. Zhai, Q. Zhan, G.S. Zhang, Q. Zhang, R. Zhang, Y. Zhang, W.Y. Zheng, B. Zhou, Z.H. Zhou, X.Y. Zhu, S. Kakkar, J.P.S. Sawhney, P. Jadhav, R. Durgaprasad, A.G. Ravi Shankar, R.K. Rajput, K. Bhargava, R. Sarma, A. Srinivas, D. Roy, U.M. Nagamalesh, M. Chopda, R. Kishore, G. Kulkarni, P. Chandwani, R.A. Pothiwala, M. Padinhare Purayil, S. Shah, K. Chawla, V.A. Kothiwale, B. Raghuraman, G. Vijayaraghavan, V.M. Vijan, G. Bantwal, V. Bisne, A. Khan, J.B. Gupta, S. Kumar, D. Jain, S. Abraham, D. Adak, A. Barai, H. Begum, P. Bhattacharjee, M. Dargude, D. Davies, B. Deshpande, P. Dhakrao, V. Dhyani, S. Duhan, M. Earath, A. Ganatra, S. Giradkar, V. Jain, R. Karthikeyan, L. Kasala, S. Kaur, S. Krishnappa, A. Lawande, B. Lokesh, N. Madarkar, R. Meena, P. More, D. Naik, K. Prashanth, M. Rao, N.M. Rao, N. Sadhu, D. Shah, M. Sharma, P. Shiva, S. Singhal, S. Suresh, V. Vanajakshamma, S.G. Panse, Y. Koretsune, S. Kanamori, K. Yamamoto, K. Kumagai, Y. Katsuda, K. Sadamatsu, F. Toyota, Y. Mizuno, I. Misumi, H. Noguchi, S. Ando, T. Suetsugu, M. Minamoto, Hiroshi Oda, K. Shiraishi, S. Adachi, K. Chiba, H. Norita, M. Tsuruta, T. Koyanagi, H. Ando, T. Higashi, K. Okada, S. Azakami, S. Komaki, K. Kumeda, T. Murayama, J. Matsumura, Y. Oba, R. Sonoda, K. Goto, K. Minoda, Y. Haraguchi, H. Suefuji, H. Miyagi, H. Kato, Tadashi Nakamura, Tsugihiro Nakamura, H. Nandate, R. Zaitsu, Yoshihisa Fujiura, A. Yoshimura, H. Numata, J. Ogawa, H. Tatematsu, Y. Kamogawa, K. Murakami, Y. Wakasa, M. Yamasawa, H. Maekawa, S. Abe, H. Kihara, S. Tsunoda, Katsumi Saito, Kazuyuki Saito, T. Fudo, K. Obunai, H. Tachibana, I. Oba, T. Kuwahata, S. Higa, M. Gushiken, T. Eto, H. Yoshida, D. Ikeda, Yoshitake Fujiura, M. Ishizawa, M. Nakatsuka, K. Murata, C. Ogurusu, M. Shimoyama, M. Akutsu, I. Takamura, F. Hoshino, N. Yokota, T. Iwao, K. Tsuchida, M. Takeuchi, Y. Hatori, Y. Kitami, Yoichi Nakamura, R. Oyama, M. Ageta, Hiroyuki Oda, Y. Go, K. Mishima, T. Unoki, S. Morii, Yuhei Shiga, H. Sumi, T. Nagatomo, K. Sanno, K. Fujisawa, Y. Atsuchi, T. Nagoshi, T. Seto, T. Tabuchi, M. Kameko, K. Nii, K. Oshiro, H. Takezawa, S. Nagano, N. Miyamoto, M. Iwaki, Yuichiro Nakamura, M. Fujii, M. Okawa, Masahiko Abe, Masatake Abe, Mitsunori Abe, T. Saito, T. Mito, K. Nagao, J. Minami, T. Mita, I. Sakuma, T. Taguchi, S. Marusaki, H. Doi, M. Tanaka, T. Fujito, M. Matsuta, T. Kusumoto, S. Kakinoki, K. Ashida, N. Yoshizawa, J. Agata, O. Arasaki, M. Manita, M. Ikemura, S. Fukuoka, H. Murakami, S. Matsukawa, Y. Hata, T. Taniguchi, T. Ko, H. Kubo, M. Imamaki, M. Akiyama, M. Inagaki, H. Odakura, T. Ueda, Y. Katsube, A. Nakata, H. Watanabe, M. Techigawara, M. Igarashi, K. Taga, T. Kimura, S. Tomimoto, M. Shibuya, M. Nakano, K. Ito, T. Seo, S. Hiramitsu, H. Hosokawa, M. Hoshiai, M. Hibino, K. Miyagawa, Hajime Horie, N. Sugishita, Yukio Shiga, A. Soma, K. Neya, Tetsuro Yoshida, Tomoki Yoshida, M. Mizuguchi, M. Ishiguro, T. Minagawa, M. Wada, H. Mukawa, F. Okuda, S. Nagasaka, Y. Abe, Sen Adachi, Susumu Adachi, T. Adachi, K. Akahane, T. Amano, K. Aoki, T. Aoyama, H. Arai, S. Arima, T. Arino, H. Asano, T. Asano, J. Azuma, T. Baba, T. Betsuyaku, H. Chibana, H. Date, J. Doiuchi, Y. Emura, M. Endo, Y. Fujii, R. Fujiki, A. Fujisawa, Y. Fujisawa, T. Fukuda, T. Fukui, N. Furukawa, T. Furukawa, W. Furumoto, T. Goto, M. Hamaoka, N. Hanazono, K. Hasegawa, T. Hatsuno, Y. Hayashi, K. Higuchi, K. Hirasawa, H. Hirayama, M. Hirose, S. Hirota, M. Honda, Hideki Horie, T. Ido, O. Iiji, H. Ikeda, K. Ikeda, K. Ikeoka, M. Imaizumi, H. Inaba, T. Inoue, F. Iseki, A. Ishihara, N. Ishioka, N. Ito, T. Iwase, H. Kakuda, J. Kamata, H. Kanai, H. Kanda, M. Kaneko, H. Kano, T. Kasai, T. Kato, Y. Kato, Y. Kawada, K. Kawai, K. Kawakami, S. Kawakami, T. Kawamoto, S. Kawano, J. Kim, T. Kira, H. Kitazawa, H. Kitazumi, T. Kito, T. Kobayashi, T. Koeda, J. Kojima, H. Komatsu, I. Komatsu, Y. Koshibu, T. Kotani, T. Kozuka, Y. Kumai, T. Kumazaki, I. Maeda, K. Maeda, Y. Maruyama, S. Matsui, K. Matsushita, Y. Matsuura, K. Mineoi, H. Mitsuhashi, N. Miura, S. Miyaguchi, S. Miyajima, H. Miyamoto, A. Miyashita, S. Miyata, I. Mizuguchi, A. Mizuno, T. Mori, O. Moriai, K. Morishita, O. Murai, Sho Nagai, Shunichi Nagai, E. Nagata, H. Nagata, A. Nakagomi, S. Nakahara, M. Nakamura, R. Nakamura, N. Nakanishi, T. Nakayama, R. Nakazato, T. Nanke, J. Nariyama, Y. Niijima, H. Niinuma, Y. Nishida, Y. Nishihata, K. Nishino, H. Nishioka, K. Nishizawa, I. Niwa, K. Nomura, S. Nomura, M. Nozoe, T. Ogawa, N. Ohara, M. Okada, K. Okamoto, H. Okita, M. Okuyama, H. Ono, T. Ono, Y. Onuki Pearce, S. Oriso, A. Ota, E. Otaki, Y. Saito, H. Sakai, N. Sakamoto, Y. Sakamoto, Y. Samejima, Y. Sasagawa, H. Sasaguri, A. Sasaki, T. Sasaki, Kazuki Sato, Kiyoharu Sato, M. Sawano, S. Seki, Y. Sekine, Y. Seta, K. Sezaki, N. Shibata, Y. Shiina, H. Shimono, Y. Shimoyama, T. Shindo, H. Shinohara, R. Shinohe, T. Shinozuka, T. Shirai, T. Shiraiwa, Y. Shozawa, T. Suga, C. Sugimoto, Kazuo Suzuki, Keita Suzuki, Shu Suzuki, Shunji Suzuki, Susumu Suzuki, Y. Suzuki, M. Tada, A. Taguchi, T. Takagi, Y. Takagi, K. Takahashi, S. Takahashi, H. Takai, C. Takanaka, S. Take, H. Takeda, K. Takei, K. Takenaka, T. Tana, G. Tanabe, K. Taya, H. Teragawa, S. Tohyo, S. Toru, Y. Tsuchiya, T. Tsuji, K. Tsuzaki, H. Uchiyama, O. Ueda, Y. Ueyama, N. Wakaki, T. Wakiyama, T. Washizuka, M. Watanabe, T. Yamada, T. Yamagishi, H. Yamaguchi, Kenichi Yamamoto, Kentaro Yamamoto, Kunihiko Yamamoto, T. Yamamoto, M. Yamaura, M. Yamazoe, K. Yasui, Y. Yokoyama, K. Yoshida, T.W. Lim, C.K. Ching, C.G. Foo, J.H. Chow, D.D. Chen, F.R. Jaufeerally, Y.M. Lee, G. Lim, W.T. Lim, S. Thng, S.Y. Yap, C. Yeo, S. Oh, H.N. Pak, J.-B. Kim, J.H. Kim, S.-W. Jang, D.H. Kim, D.R. Ryu, S.W. Park, D.-K. Kim, D.J. Choi, Y.S. Oh, M.-C. Cho, S.-H. Kim, H.-K. Jeon, D.-G. Shin, J.S. Park, H.K. Park, S.-J. Han, J.H. Sung, J.-G. Cho, G.-B. Nam, Y.K. On, H.E. Lim, J.J. Kwak, T.-J. Cha, T.J. Hong, S.H. Park, J.H. Yoon, N.-H. Kim, K.-S. Kim, B.C. Jung, G.-S. Hwang, C.-J. Kim, D.B. Kim, J.J. Ahn, H.J. An, H. Bae, A.L. Baek, W.J. Chi, E.A. Choi, E.H. Choi, H.K. Choi, H.S. Choi, S. Han, E.S. Heo, K.O. Her, S.W. Hwang, E.M. Jang, H.-S. Jang, S. Jang, H.-G. Jeon, S.R. Jeon, Y.R. Jeon, H.K. Jeong, I.-A. Jung, Hyeon Jeong Kim, Hyun Ju Kim, Ji Seon Kim, Jung Sook Kim, J.A. Kim, K.T. Kim, M.S. Kim, Sang Hee Kim, Sang Hyun Kim, Y.-I. Kim, C.S. Lee, E.H. Lee, G.H. Lee, H.Y. Lee, H.-Y. Lee, K.H. Lee, K.R. Lee, M.S. Lee, M.-Y. Lee, R.W. Lee, S.E. Lee, S.H. Lee, S. Lee, W.Y. Lee, I.K. Noh, A.R. Park, B.R. Park, H.N. Park, J.H. Park, M. Park, Y. Park, S.-Y. Seo, J. Shim, J.H. Sim, Y.M. Sohn, W.S. Son, Y.S. Son, H.J. Song, H.K. Wi, J.J. Woo, S. Ye, K.H. Yim, K.M. Yoo, E.J. Yoon, S.Y. Yun, P. Angchaisuksiri, S. Chawanadelert, P. Mongkolwongroj, K. Kanokphatcharakun, S. Cheewatanakornkul, T. Laksomya, S. Pattanaprichakul, T. Chantrarat, S. Rungaramsin, S. Silaruks, W. Wongcharoen, K. Siriwattana, K. Likittanasombat, P. Katekangplu, W. Boonyapisit, D. Cholsaringkarl, B. Chatlaong, P. Chattranukulchai, Y. Santanakorn, P. Hutayanon, P. Khunrong, T. Bunyapipat, S. Jai-Aue, P. Kaewsuwanna, P. Bamungpong, S. Gunaparn, S. Hongsuppinyo, R. Inphontan, R. Khattaroek, K. Khunkong, U. Kitmapawanont, C. Kongsin, B. Naratreekoon, S. Ninwaranon, J. Phangyota, A. Phrommintikul, P. Phunpinyosak, K. Pongmorakot, S. Poomiphol, N. Pornnimitthum, S. Pumprueg, S. Ratchasikaew, K. Sanit, K. Sawanyawisuth, B. Silaruks, R. Sirichai, A. Sriwichian, W. Suebjaksing, P. Sukklad, T. Suttana, A. Tangsirira, O. Thangpet, W. Tiyanon, Y. Vorasettakarnkij, T. Wisaratapong, W. Wongtheptien, A. Wutthimanop, S. Yawila, A. Oto, A. Altun, I. Ozdogru, K. Ozdemir, O. Yilmaz, A. Aydinlar, M.B. Yilmaz, E. Yeter, Z. Ongen, M. Cayli, H. Pekdemir, M. Ozdemir, M. Sucu, T. Sayin, M. Demir, H. Yorgun, M. Ersanli, E. Okuyan, D. Aras, H. Abdelrahman, O. Aktas, D. Alpay, F. Aras, M.F. Bireciklioglu, S. Budeyri, M. Buyukpapuc, S. Caliskan, M. Esen, M.A. Felekoglu, D. Genc, B. Ikitimur, E.B. Karaayvaz, S. Kılıç Karataş, S. Okutucu, E. Ozcelik, A. Quisi, H. Sag, L. Sahiner, B.Y. Sayin, T. Seker, D. Uzun Alkan, E. Yildirim, R. Yildirim, F. Yilmaz, V. Yuksekdag, H.L. Luciardi, N. Vensentini, A.C. Ingaramo, G.A. Sambadaro, V. Fernandez Caputi, S.G. Berman, P. Dragotto, A.J. Kleiban, N. Centurion, G. Giacomi, R.A. Ahuad Guerrero, D. Conde, G. Zapata, L.A. Di Paola, J.L. Ramos, R.D. Dran, J. Egido, A.A. Fernandez, M.J. Fosco, S. Sassone, V.A. Sinisi, L.R. Cartasegna, M.A. Berli, O.A. Gomez Vilamajo, F. Ferroni, E.D. Alaguibe, A. Alvarez D'Amelio, C. Arabetti, L. Arias, J.A. Belardi, L. Bergesio, F. Berli, M. Berli, S. Borchowiec, C. Buzzetti, R. Cabrini, V. Campisi, A.L. Cappi, R. Carrizo, F. Colombo Berra, J.P. Costabel, O.J.A. Costamagna, A.A. Damonte, I.N. De Urquiza, F. Diez, M.F. Edén, M. Fanuele, F. Fernandez Voena, M. Foa Torres, C. Funosas, M.P. Giacomi, C.H. Gimenez, E.P. Gurfinkel, M. de L.M. Had, V. Hansen, A.D. Hrabar, M. Ingratta, A. Lopez, G. Maehara, L. Maffei, A. Martinelli, C. Martinelli, J. Matkovich, B. Mautner, A. Meirino, R. Munguia, A. Navarro, V. Novas, G. Perez Prados, J. Pontoriero, R.N. Potito, C. Ricotti, M.A. Rodriguez, F. Rolandi, M.E. Said Palladino, M. Salinger, L.S. Sanziani, P.O. Schygiel, A. Sossich, J.F. Tinto, L. Tonelli, A.L. Tufare, M. Vallejo, M.E. Yunis, M. Zillo, F.J. Zurbrigk, A.C.P. Barretto, D.C. Sobral Filho, J. Jaber, D. Armaganijan, J. Faria Neto, A. Steffens, W. Kunz Sebba Barroso de Souza, J.D. de Souza Neto, J.M. Ribeiro, M. Silveira Teixeira, P.R. Ferreira Rossi, L. Pires, D. Moreira, J.C. Moura Jorge, A. Menezes Lorga Filho, L.C. Bodanese, M. Westerlund Montera, C.H. Del Carlo, T. Da Rocha Rodrigues, F.A. Alves da Costa, A. Lopes, R. Lopes, G.R. Araújo, E.R. Fernandes Manenti, J.F. Kerr Saraiva, J.C. Ferreira Braga, A. Negri, L. Souto, C. Moncada, D. Bertolim Precoma, F. Roquette, G. Reis, R.A. Ramos Filho, E. Lanna Figueiredo, R. Vieira Botelho, C. Munhoz da Fontoura Tavares, C.R. Costantini Frack, J. Abdalla Saad, H.C. Finimundi, C. Pisani, D. Chemello, M. Pereira Martins, C.C. Broilo França, F. Alban, G.B. Aranha Rosito, J.B. de Moura Xavier Moraes Junior, R.T. Tumelero, L. Nigro Maia, R. Simões de Almeida, N.C. do Carmo Borges, L.G. Gomes Ferreira, P. Agliardi, J. Alves de Oliveira Gomes, V. Araujo, M. Arruda Nakazone, T. Barbosa, S. Barroso, E. Belisario Falchetto, H. Bellotti Lopes, M.A. Benez Teixeira Lemos, G. Biazus, L. Borges Queiroz, F.E. Camazzola, M. Caporale, S. Cardoso Boscato, F. Chieza, M.O. Chokr, R. Clemente Mingireanov, N. Codonho Góes, C. Correa, M. Costa, C. Costantini Ortiz, L.S. da Silva, F. da Silva Paulitsch, J.A. da Silveira, E. Daros, G.R. de Araújo, M.I. Del Monaco, C. Dias, M.A. Dias, A.P. Drummond Wainstein, P. Ely Pizzato, D.C. Esteves, P. Fabri, T. Félix Lorenzato Fonseca, E. Fernandes, C. Fonseca, C.R. Frack Costantini, R. Franchin Ferraz, F. Freire, P. Gottardo, D. Guanaes, S. Guizzardi, E. Hettwer Magedanz, F. Igansi, F. Jannuzzi, G. Junior, D. Komar, E.G. Lino, D. Lopes, O. Lourenço da Silva Júnior, E. Lustosa, A.P. Macagnan, M.C. Marinho, M. Mazzoni, G. Melo, L. Mortari, O.M.C.C. Mouco, C. Nanzer Vital, C. Ormundo, S. Oss Emmer, E. Palmegiani, R. Pavani, L. Pereira, V.L. Pereira, R. Perreira, S. Poletti, S.C. Quaia Fortunato, C. Queirantes, N. Ramos Pereira, R.L. Rech, S. Ribeiro, A. Rodrigues, H. Roesch, T. Ruaro Reichert, D. Santos, I. Santos, M. Santos, M.V. Seroqui, S. Silva, L. Soares, L. Spolaor, C. Stoll, N. Toazza Duda, L. Trama, B. Unterkircher, M.V. Valois, T. Vargas, T. Viana, C. Vicente, L. Vidal Armaganijan, R. Vieira Homem, L.G. Vieira Torres, L. Vila Boas, F. Villaça Guimarães Filho, R. Corbalan, G. Eggers, C. Bugueño Gutiérrez, G. Arriagada, S. Potthoff Cardenas, B.A.J. Stockins Fernandez, C. Conejeros, C. Houzvic, P. Marin Cuevas, H. Montecinos, A. Forero, F. Lanas, M. Larico Gómez, G. Charme Vilches, C. Rey, C. Astudillo, J. Aguilar, Y. Campisto, C. Lara, E. Molina, J. Munoz Oyarzon, V. Olguin, M. Vergara, C. Villan, C.J. Sánchez Díaz, J. Illescas Diaz, R. Leal Cantú, M.G. Ramos Zavala, R. Cabrera Jardines, N. Espinola Zavaleta, S. Villarreal Umaña, E. López Rosas, G. Llamas Esperón, G. Pozas, E. Cardona Muñoz, N. Matadamas Hernández, A. Leyva Rendón, N. García Hernández, M. de los Ríos Ibarra, L. Virgen Carrillo, D. López Villezca, C. Hernández Herrera, J.J. López Prieto, R. Gaona Rodríguez, E. Villeda Espinosa, D. Flores Martínez, J. Velasco Barcena, R. Yong, I. Rodríguez Briones, J.L. Leiva Pons, H. Álvarez López, R. Olvera Ruiz, C. Díaz de la Vega, C. Cantú Brito, E. Chuquiure Valenzuela, R. Reyes-Sanchez, A. Bazzoni Ruiz, O. Nandayapa Flores, M. Benavides Gonzalez, R. Arriaga Nava, J.D. Morales Cerda, O. Fierro Fierro, P. Fajardo Campos, T.A.A. Alfaro, S. Altamirano Bellorin, R. Avena, M. Chavarria, I. Espinosa, F. Flores Silva, R.H. Garcia Nava, K. Godoy, E.J. Gonzalez Felix, C.L. Gonzalez Garcia, L.G. Gonzalez Salas, P. Guajardo, S. Hernandez Gonzalez, T. Izquierdo, M.C. Mancilla Ortiz, D. Martinez Vasquez, N. Mendoza, J. Morales, N. Nikitina, S. Ochoa Aybar, A. Ortiz, P. Padilla Macias, F. Perez, J.A. Perez Sanchez, S. Piña Toledano, M. Ramos Gonzalez, C. Rivera Ramos, V. Roa Castro, G. Romero Cardona, M. Ruiz Cornejo, A. Salinas, G. Santana, P. Sida Perez, A.C. Tovar Castaneda, R. Trujillo Cortes, M. Brodmann, K. Lenz, H. Drexel, J. Foechterle, C. Hagn, A. Podczeck-Schweighofer, K. Huber, M. Winkler, B. Schneeweiß, A. Gegenhuber, W. Lang, S. Eichinger-Hasenauer, P. Kaserer, J. Sykora, H. Rasch, M. Pichler, E. Schaflinger, B. Strohmer, R. Breier, K.-M. Ebner, L. Eischer, F. Freihoff, A. Lischka-Lindner, T. Mark, A. Mirtl, A. Said, C. Stöcklöcker, B. Vogel, A. Vonbank, C. Wöhrer, D. Zanolin, F. Cools, G. Paparella, P. Vandergoten, J.-L. Parqué, L. Capiau, G. Vervoort, B. Wollaert, P. Desfontaines, G. Mairesse, T. Boussy, P. Godart, A. De Wolf, J. Voet, A. Heyse, G. Hollanders, W. Anné, J. Vercammen, P. Purnode, I. Blankoff, D. Faes, Y. Balthazar, M. Beutels, P. Maréchal, S. Verstraete, O. Xhaet, H. Striekwold, J. Thoeng, K. Hermans, B. Alzand, A.-K. Ascoop, F. Banaeian, A.-M. Barbuto, A.C. Billiaux, M. Blockmans, C. Bouvy, C. Brike, H. Capiau, T. Casier, A. Conde Y Bolado, D. De Cleen, M. De Coninck, M. de Vos, N. de Weerdt, M. Delforge, M. Delvigne, D. Denie, K. Derycker, E. Deweerd, F. Dormal, S. Drieghe, M. Everaert, T. Eykerman, E. Feys, M. Ghekiere, F. Gits, S. Hellemans, L. Helvasto, C. Jacobs, S. Lips, I. Mestdagh, J. Nimmegeers, V. Piamonte, P. Pollet, A. Postolache, M. Raepers, E. Raymenants, J. Richa, H. Rombouts, J. Salembier, C. Scheurwegs, O. Semeraro, N. Simons, C. Smessaert, W. Smolders, I. Stockman, S. Tahon, V. Thyssen, G. Tincani, F. Van Durme, D. Van Lier, H. Vandekerckhove, Y. Vandekerckhove, D. Vandenbroeck, A. Vandorpe, E. Vanhalst, B. Vanhauwaert, C. Vantomme, L. Vergauwen, H. Verloove, T. Vydt, T. Weyn, P. Jansky, P. Reichert, R. Spacek, V. Machova, E. Zidkova, O. Ludka, J. Olsr, L. Kotik, K. Plocova, B. Racz, R. Ferkl, J. Hubac, I. Kotik, Z. Monhart, H. Burianova, O. Jerabek, J. Pisova, I. Petrova, V. Dedek, M. Honkova, P. Podrazil, J. Spinar, J. Vitovec, M. Novak, J. Lastuvka, V. Durdil, P. Antonova, L. Bockova, J. Bultas, J. Chlumsky, L. Dastychova, T. Drasnar, J. Honek, M. Horejsi, V. Hubacova, L. Janska, I. Kopeckova, R. Kratochvilova, E. Krcova, R. Labrova, A. Lindourkova, J. Lipoldova, H. Lubanda, A. Ludkova, L. Mahdalikova, M. Majerníkova, D. Michalik, P. Potuznik, E. Prochazkova, A. Sulc, J. Sveceny, M. Valtova, M. Zidek, J. Zika, J. Nielsen, H. Nielsen, S. Husted, U. Hintze, S. Rasmussen, A. Bremmelgaard, J. Markenvard, J. Boerger, J. Solgaard, P. Simonsen, T. Loekkegaard, M. Bruun, J. Mertz, H. Domínguez, K. Skagen, K. Egstrup, H. Ibsen, I. Raymond, T. Bang-Hansen, C. Ellervik, E. Eriksen, L. Jensen, M. Jensen, M. Leth, A. Nygaard, J. Park, M. Schou, A. Therkelsen, J. Tilma, K. Vesterager, P. Raatikainen, J. Airaksinen, O. Arola, J. Koistinen, H. Nappila, K. Peltomäki, V. Rasanen, T. Vasankari, J.-Y. Le Heuzey, M. Galinier, Y. Gottwalles, F. Paganelli, P. Loiselet, J.-J. Muller, M.B. Koujan, A. Marquand, S. Destrac, O. Piot, N. Delarche, J.-P. Cebron, S. Boveda, M. Guenoun, D. Guedj-Meynier, D. Galley, J. Ohayon, S. Assouline, M. Zuber, P. Amarenco, E. Ellie, J. Kadouch, P.-Y. Fournier, J.-P. Huberman, M. Lemaire, G. Rodier, L. Milandre, X. Vandamme, I. Sibon, J.-P. Neau, M.H. Mahagne, A. Mielot, M. Bonnefoy, J.-B. Churet, V. Navarre, F. Sellem, G. Monniot, J.-P. Boyes, B. Doucet, M. Martelet, D. Obadia, B. Crousillat, J. Mouallem, E. Bearez, P. Nazeyrollas, J.P. Brugnaux, A. Fedorowsky, F. Casassus, J.-B. Berneau, F. Chemin, N. Falvo, J.-M. Perron, J.-E. Poulard, A. Barreau, C. Beltra, E. Corrihons, N. Decarsin, B. Dubois, E. Ducasse, X. Giry, A. Kemmel, S. Ledure, N. Lemaire, F. Robin, N. Rosolin, D. Sanchez, A. Suissa, H. Darius, G. Königer, J. Purr, U. Gerbaulet, B.-T. Kellner, A. Kopf, T. Schäfer, H. Zauzig, P. Riegel, H. Hohensee, E. Eißfeller, W. Eder, G. Rehling, D. Glatzel, S. Zutz, G.-U. Heinz, H. Menke, A. Pustelnik, P. Sandow, N. Ludwig, H. Wiswedel, W. Wildenauer, C. Axthelm, T. Schwarz, A. Babyesiza, G. Stuchlik, H.-H. Zimny, M. Kropp, F. Kahl, A. Caspar, S. Omankowsky, T. Läßig, H.-J. Hartmann, G. Lehmann, H.-W. Bindig, G. Hergdt, D. Reimer, J. Hauk, W. Dorsch, J. Dshabrailov, H. Michel, K.-A. Rapp, R. Vormann, P. Mayer, U. Horstmeier, V. Eissing, H. Hey, H. Leuchtgens, V. Lilienweiß, K. Kolitsch, C. Schubert, H. Lauer, T. Buchner, G. Brauer, S. Kamin, K. Müller, M. Abdel-Qader, S. Baumbach, H.-H. Ebert, C. Schwencke, S. Schellong, P. Bernhardt, L. Karolyi, B. Sievers, W. Haverkamp, P. Salbach, J.-U. Röhnisch, S. Schoen, W. Erdle, T. Mueller, H. Mueller, V. Mitrovic, Z. Babjakova, K. Bergner, S. Boehme, K. Bonin, D. Buckert, F. Busch, U. Dichristin, S. Diez, A. Fleck, K. Flint, H. Floegel, C. Fritz, R. Frommhold, J. Gehre, J. Geyer, A. Grytzmann, M. Hahn, K. Helgert, K. Hubert, K. Kirchner-Volker, V. Klein, D. Kroll, A. Krueger, R. Lehmann, L. Mann, A. Maselli, G. Menken, K. Mikes, H. Mortan, N. Nasser, D. Nicolaus, A. Plauskat, L. Pomper, A. Quietzsch, C. Ravenhorst, C. Reichelt, C. Reimer, B. Schaefer, S. Scharrer, K. Schirmer, K. Schmidt, R. Schoene, J. Schulze, M. Schuppe, S. Simon, S. Sommer, K. Spranger, A. Talkenberger, K. Tauber, A. Tetlak, T. Toennishoff, R. Voelkel-Babyesiza, B. Voigts, U. Weiser, S. Wesendorf, S. Wildenauer, T. Wolf, J. Wurziger, J. Zak, H.-D. Zauzig, S. Ziefle, S. Zincke, M. Keltai, S. Vangel, G. Szalai, B. Merkely, S. Kancz, Z. Boda, A. Nagy, Z. Laszlo, A. Matoltsy, B. Gaszner, P. Polgar, T. Habon, E. Noori, G. Juhasz, N. Kanakaridisz, I. Szentpeteri, F. Juhasz, A. Vertes, A. Papp, Z. May, J. Ferenczi, M. Egyutt, E. Kis, G. Engelthaler, G. Szantai, E. Fulop, P. Gombos, D. Gulyas, P. Jen, E. Kiralyhazine Gyorke, M. Kovacs, S. Kovacsne Levang, S. Marianna, Z. Radics, N. Sydó, R. Szalo, A. Szilagyi, F. Sztanyik, B. Vandrus, G. Agnelli, G. Ambrosio, E. Tiraferri, R. Santoro, S. Testa, G. Di Minno, M. Moia, T.M. Caimi, G. Martini, M. Tessitori, R. Cappelli, D. Poli, R. Quintavalla, F. Melone, F. Cosmi, A. Pizzini, G. Piseddu, R. Fanelli, C. Latella, R. Santi, L. Pancaldi, R. De Cristofaro, G. Palareti, A. De Blasio, J. Salerno Uriarte, F. Minetti, E.M. Pogliani, L.M. Lonati, M. Accogli, N. Ciampani, S. Malengo, M. Feola, A. Raisaro, L. Fattore, P. Grilli, F. Germini, M. Settimi, M. Alunni, G. Duranti, L. Tedeschi, G. Baglioni, G. Avanzino, M. Berardi, V. Pannacci, A. Giombolini, S. Nicoli, T. Scarponi, B. Allasia, P. Ricciarini, R. Nasorri, A. Argena, P. Bossolasco, P. Ronchini, A. Filippi, F. Tradati, C. Bulla, L. Donzelli, L. Foppa, M.L. Bottarelli, A. Tomasello, A. Mauric, C. Femiano, R. Reggio, F. Lillo, A. Mariani, F. Forcignanò, M. Volpe, M. D'Avino, M.G. Bongiorni, S. Severi, A. Capucci, C. Lodigiani, E. Salomone, G. Serviddio, C. Tondo, P. Golino, C. Mazzone, S. Iacopino, V. Pengo, M. Galvani, L. Moretti, P. Ambrosino, E. Banfi, V. Biagioli, A. Bianchi, G. Boggian, M. Breschi, S. Brusorio, F. Calcagnoli, G. Campagna, M. Carpenedo, C. Ciabatta, G. Ciliberti, G. Cimmino, C. D'Arienzo, L. Di Gennaro, M. Fedele, P.M. Ferrini, K. Granzow, G. Guazzaloca, F. Guerra, A. Lo Buglio, S. Longo, F. Macellari, E. Mesolella, E. Mollica Poeta, P. Occhilupo, V. Oriana, G. Rangel, L. Salomone, A. Scaccianoce, C. Scarone, L. Segreti, G. Sottilota, R. Villani, C. Zecca, H. ten Cate, J.H. Ruiter, H. Klomps, M. Bongaerts, M.G.C. Pieterse, C. Guldener, J.-P. Herrman, G. Lochorn, A. Lucassen, H. Adriaansen, S.H.K. The, P.R. Nierop, P.A.M. Hoogslag, W. Hermans, B.E. Groenemeijer, W. Terpstra, C. Buiks, L.V.A. Boersma, M. Boersma-Slootweg, F. Bosman, M. Bosschaert, S. Bruin, I. Danse, J. De Graaf, J. de Graauw, M. Debordes, S. Dols, F. Geerlings, K. Gorrebeeck, A. Jerzewski, W. Jetten, M. Kelderman, T. Kloosterman, E.M. Koomen, J. Krikken, P. Melman, R. Mulder, A. Pronk, A. Stallinga-de Vos, J. te Kaat, P. Tonino, B. Uppelschoten, R. van de Loo, T. van der Kley, G. van Leeuwen, J.J. van Putten, L. Westerman, D. Atar, E. Berge, P.A. Sirnes, E. Gjertsen, T. Hole, K. Erga, A. Hallaråker, G. Skjelvan, A. Østrem, B. Ghezai, A. Svilaas, P. Christersson, T. Øien, S. Høegh Henrichsen, J. Berg-Johansen, J.E. Otterstad, H. Antonsen, K. Ausen, H. Claussen, I. Dominguez, A. Jekthammer, A.B. Lensebraaten, V. Nilsen, M. O'Donovan, K. Ringdalen, S. Strand, J. Stepinska, R. Korzeniak, A. Gieroba, M. Biedrzycka, Marcin Ogorek, B. Wozakowska-Kaplon, K. Loboz-Grudzien, J. Kosior, W. Supinski, J. Kuzniar, R. Zaluska, J. Hiczkiewicz, L. Swiatkowska-Byczynska, L. Kucharski, M. Gruchala, P. Minc, M. Olszewski, G. Kania, M. Krzciuk, Z. Lajkowski, B. Ostrowska-Pomian, J. Lewczuk, E. Zinka, A. Karczmarczyk, M. Chmielnicka-Pruszczynska, M. Trusz-Gluza, G. Opolski, M. Bronisz, Michal Ogorek, G. Glanowska, P. Ruszkowski, K. Jaworska, R. Sciborski, B. Okopien, P. Kukla, I. Wozniak-Skowerska, K. Galbas, K. Cymerman, J. Jurowiecki, P. Miekus, W. Myszka, S. Mazur, R. Lysek, J. Baszak, T. Rusicka-Piekarz, G. Raczak, E. Domanska, J. Nessler, J. Lesnik, M. Ambicka, D. Andrzejewski, J. Araminowicz, A. Barszcz, R. Bartkowiak, J. Bartnik, M. Basiak, E. Bekieszczuk, L. Bernat, L. Biedrzycki, A. Biernacka, D. Blaszczyk, E. Broton, W. Brzozowski, M. Brzustowska, R. Bzymek, A. Chmielowski, P. Chojnowski, R. Cichomski, K. Cieslak, A. Cieszynska, B. Curyllo, M. Czamara, L. Danilowicz-Szymanowicz, B. Dolecka, L. Drelich, B. Dudzik-Richter, T. Dybala, M. Dziuba, W. Faron, M. Figura-Chmielewska, A. Frankiewicz, W. Gadzinski, E. Gasior, B. Gosciniecka, P. Gutknecht, M. Guziewicz, A. Jackun-Podlesna, G. Jaguszewska, J. Jankielewicz, A. Jaremczuk-Kaczmarczyk, M. Jargiello-Baszak, A. Jarzebowski, E. Jaskulska-Niedziela, M. Jaworska-Drozdowska, J. Kabat, A. Kaczmarzyk-Radka, K. Kalin, R. Kaliszczak, M. Kiliszek, M. Klata, M. Kluczewski, I. Kobielusz-Gembala, E. Kochanska, D. Kociolek, A. Kolodzinska, A. Komlo, A. Konopka, E. Korczowska, E. Kowal, H.K. Kowalczyk, E. Kremis, D. Kruczyk, A. Krzesiak-Lodyga, M. Krzyzanowski, W. Kurdzielewicz, D. Kustrzycka-Kratochwil, D. Lesniewska-Krynska, J. Leszczynski, E. Lewicka, E. Lichota, K. Lip, M. Loboz-Rudnicka, J. Luka, A. Lysek-Jozefowicz, M. Machnikowska, K. Majewska, R. Mariankowski, A. Markiewicz, M. Mazur, A. Metzgier-Gumiela, E. Miedlar, M. Mielcarek, J. Neubauer-Geryk, J. Niedek, A. Niemirycz-Makurat, A. Nowak, S. Nowak, B. Opielowska-Nowak, M. Ozgowicz, A. Pawelska-Buczen, E. Pawlik-Rak, R. Piotrowicz, P. Ptaszynski, A. Raczynska, W. Rogowski, J. Romanek, R. Romaszkiewicz, P. Rostoff, N. Roszczyk, D. Rozewska-Furmanek, J. Rychta, B. Rzyczkowska, A. Sidor, J. Skalska, M. Smichura, M. Splawski, P. Staneta, E. Staniszewska, J. Starak-Marciniak, M. Stopyra-Poczatek, M. Sukiennik-Kujawa, J. Szafranski, P. Szalecki, A. Szczepanska, W. Szkrobka, E. Szuchnik, A. Szulowska, G. Szumczyk-Muszytowska, M. Szwoch, T. Traczyk, M. Troszczynska, G. Trzcinski, S. Tybura, P. Walasik, M. Wegrzynowska, K. Wesolowska, W. Wieczorek, A. Wierzbicka, P. Wilczewski, M. Wilgat-Szecowka, P. Wojewoda, L. Wojnowski, M. Wrobel, K. Zakutynska-Kowalczyk, M. Zyczynska-Szmon, E. Panchenko, V. Eltishcheva, R. Libis, S. Tereshchenko, S. Popov, G. Kamalov, D. Belenky, A. Zateyshchikova, E. Kropacheva, A. Kolesnikova, K. Nikolaev, L. Egorova, A. Khokhlov, E. Yakupov, M. Poltavskaya, D. Zateyshchikov, O. Drapkina, A. Vishnevsky, O. Barbarash, O. Miller, E. Aleksandrova, P. Chizhov, M. Sergeev, E. Shutemova, E. Mazur, K. Zrazhevskiy, T. Novikova, V. Kostenko, Y. Moiseeva, E. Polkanova, K. Sobolev, M. Rossovskaya, G. Zubeeva, Y. Shapovalova, O. Nagibovich, A. Edin, A. Agakhanyan, R. Batalov, Y. Belenkova, F. Bitakova, S. Chugunnaya, A. Dumikyan, S. Erofeeva, E. Gorbunova, T. Gorshkova, A. Gubanov, M. Gurmach, Y. Ivanova, T. Kolesova, D. Konyushenko, O. Korneeva, O. Kropova, P. Kuchuk, O. Kungurtseva, T. Kupriyanova, B. Kurylo, M. Kuvanova, O. Lebedeva, E. Lileeva, O. Machilskaya, T. Medvedeva, G. Monako, I. Motylev, G. Nagibovich, E. Novikova, Y. Orlov, Y. Osmolovskaya, A. Ovsannikova, D. Platonov, S. Rachkova, O. Sinitsina, S. Speshilova, O. Suslova, A. Ushakov, O. Volodicheva, O. Zemlianskaia, I. Zhirov, E. Zhuravleva, I. Zotova, X. Viñolas, P. Alvarez Garcia, M.F. López Fernández, L. Tercedor, S. Tranche Iparraguirre, P. Torán Monserrat, E. Márquez Contreras, J. Isart Rafecas, J. Motero Carrasco, P. García Pavía, C. Gómez Pajuelo, C. Moro Serrano, L.F. Iglesias Alonso, A. Grande Ruiz, J. Mercé Klein, J.R. Gonzalez Juanatey, G. Barón Esquivias, I. Monte Collado, H. Palacín Piquero, C. Brotons Cuixart, M. Rodríguez Morató, J. Bayo I Llibre, C. Corros Vicente, M. Vida Gutierrez, F. Epelde Gonzalo, C.A. Almeida Fernández, N. Del Val Plana, E. Escrivá Montserrat, J.J. Montero Alía, M. Barreda González, M.A. Moleiro Oliva, J. Iglesias Sanmartín, M. Jiménez González, M. Rodriguez Álvarez, J. Herreros Melenchon, T. Ripoll Vera, F. Ridocci Soriano, L. Garcia Riesco, M.D. Marco Macian, J. Quiles Granado, M. Jimenez Navarro, J. Cosin Sales, J.V. Vaquer Perez, M. Vazquez Caamano, M.F. Arcocha Torres, G. Marcos Gomez, A. Iñiguez Romo, M.A. Prieto Diaz, Carmela Alonso, Concepcion Alonso, D. Alvarez, M. Alvarez, M. Amaro, N. Andere, J. Aracil Villar, R. Armitano Ochoa, A. Austria, S. Barbeira, E. Barraquer Feu, A. Bartes, V. Becerra Munoz, F.J. Bermudez Jimenez, A. Branjovich Tijuan, J. Cabeza Ramirez, M. Cabrera Ramos, E. Calvo Martinez, M. Campo Moreno, G. Cancho Corchado, M. Casanova Gil, M. Castillo Orive, D. Castro Fernandez, M. Cebollada del Misterio, R. Codinachs Alsina, A. Cortada Cabrera, J. Costa Pinto Prego de Faria, S. Costas, M.I. Cotilla Marco, M. Dachs, C.M. Diaz Lopez, A. Domenech Borras, A. Elorriaga Madariaga, A. Espallargas, M. Fernandez, E. Fernandez Escobar, E. Fernandez Mas, A. Ferrer, J. Fosch, M. Garcia Bermudez, V. Garcia Millan, M. Gavira Saenz, C. Gines Garcia, C. Gomez, Y. Gomez Perez, A. Gonzales Segovia, P. Gonzalez, L. Grigorian, A. Guerrero Molina, M. del C. Gutierrez del Val, B. Herrero Maeso, E. Hevia Rodriguez, A. Iglesias Garcia, M.J. Jimenez Fernandez, B. Jimeno Besa, P. Juan Salvadores, M.B. Lage Bouzamayor, I. Lasuncion, L.E. Lezcano Gort, M. Llobet Molina, M. Lopez, A. Manzanal Rey, J. Mara Guerra, S. Marcus, A. Martin Vila, M. Martinez Mena, P. Mazon, F. Mendez Zurita, G. Millán, M. Molina, P. Montero Alia, D. Montes, M. Moure Gonzalez, R.B. Munoz Munoz, A. Negrete Palma, H.N. Orellana Figueroa, V.M. Ortega, C. Ortiz Cortes, D. Otero Tomera, N. Palomo Merchan, I. Pareja Ibar, E. Pena Garcia, M. Pereda Armayor, M. Perez Carasa, I. Prieto, V. Quintern, R. Renom, L.M. Rincon Diaz, V. Rios, L. Riquelme Sola, R. Rivera, X. Robiro Robiro, M. Roca, C. Roca Saumell, C. Rodrigo, E. Rodriguez, M. Rodriguez Garcia, S. Saez Jimenez, P. Sanchez Calderon, L. Sanchez Mendez, S. Sanchez Parra, C. Santolaya, M.R. Senan Sanz, A. Seoane Blanco, E. Serralvo, N. Sierra, C. Simon Valero, J. Sorribes Lopez, M. Teixido Fontanillas, M. Terns Riera, G. Tobajas, C. Torres, J. Torres Marques, M. Ubeda Pastor, M. Rosenqvist, A. Wirdby, J. Linden, K. Henriksson, M. Elmersson, A. Egilsson, U. Börjesson, G. Svärd, B. Liu, A. Lindh, L.-B. Olsson, M. Gustavsson, Lars Andersson, Lisbeth Andersson, L. Benson, C. Bothin, A. Hajimirsadeghi, K. Kadir, M. Ericsson, A. Ohlsson, H. Lindvall, P. Svensson, K. Thorne, H. Handel, P. Platonov, B. Eriksson, I. Timberg, K. Romberg, M. Crisby, J.-E. Karlsson, S.A. Jensen, A. Andersson, L. Malmqvist, B. Martinsson, F. Bernsten, J. Engdahl, J. Thulin, A. Hot-Bjelac, P. Stalby, H. Aaröe, E. Ahbeck, H. Ahlmark, F. Al-Khalili, G. Bonkowski, S. Dzeletovic, A.-B. Ekstrand, G.-B. Eriksson, K. Floren, C. Grässjö, S. Hahn, P. Jaensson, B. Jansson, J.-H. Jansson, R.-M. Kangert, A. Koch, D. Kusiak, A. Lettenström, A. Lindberg, C.-J. Lindholm, A. Mannermyr, K. Mansson, M. Millborg, C. Nilsson, A.-M. Ohlin, A. Olofsson, A. Osberg, A. Pedersen, K. Risbecker, K. Rosenberg, J. Samuelsson, M. Shayesteh, K. Skoglund, M. Stjernberg, C. Thorsen, J. Steffel, J.H. Beer, J. Debrunner, D. Amstutz, J. Bruegger, G. Elise, A. Grau, A. Guinand, I. Henriette, E. Saga, S. Winnik, A. Parkhomenko, I. Rudyk, V. Tseluyko, O. Karpenko, S. Zhurba, I. Kraiz, I. Kupnovytska, N. Serediuk, Y. Mostovoy, O. Ushakov, O. Koval, I. Kovalskyi, Y. Svyshchenko, O. Sychov, M. Stanislavchuk, O. Kraydashenko, A. Yagensky, S. Tykhonova, I. Fushtey, R. Belegai, G. Berko, L. Burdeuna, O. Chabanna, I. Daniuk, A. Ivanov, E. Kamenska, P. Kaplan, O. Khyzhnyak, S. Kizim, O. Matova, O. Medentseva, V. Mochonyi, M. Mospan, V. Nemtsova, T. Ovdiienko, O. Palamarchuk, M. Pavelko, R. Petrovskyy, D. Plevak, O. Proshak, S. Pyvovar, L. Rasputina, O. Romanenko, O. Romanova, A. Sapatyi, O. Shumakov, R. Stets, L. Todoriuk, V. Varenov, D. Fitzmaurice, N. Chauhan, D. Goodwin, P. Saunders, R. Evans, J. Leese, P.S. Jhittay, A. Ross, M.S. Kainth, G. Pickavance, J. McDonnell, A. Williams, T. Gooding, H. Wagner, S. Suryani, A. Singal, S. Sircar, R. Bilas, P. Hutchinson, A. Wakeman, M. Stokes, N. Paul, M. Aziz, C. Ramesh, P. Wilson, S. Franklin, S. Fairhead, J. Thompson, V. St Joseph, G. Taylor, D. Tragen, D. Seamark, C. Paul, M. Richardson, A. Jefferies, H. Sharp, H. Jones, C. Giles, M. Page, O. Oginni, J. Aldegather, S. Wetherwell, W. Lumb, P. Evans, F. Scouller, N. Macey, Y. Stipp, R. West, S. Thurston, P. Wadeson, J. Matthews, P. Pandya, A. Gallagher, T. Railton, B. Sinha, D. Russell, J.A. Davies, P. Ainsworth, C.P. Jones, P. Weeks, J. Eden, D. Kernick, W. Murdoch, L. Lumley, R.P. Patel, S.W. Wong, M. Saigol, K. Ladha, K. Douglas, D.F. Cumberlidge, C. Bradshaw, G. Van Zon, K.P. Jones, M.J. Thomas, E. Watson, B. Sarai, N. Ahmad, W. Willcock, J. Cairns, S. Sathananthan, N. de Kare-Silver, A. Gilliland, E. Strieder, A. Howitt, B. Vishwanathan, N. Bird, D. Gray, M. Clark, J. Bisatt, J. Litchfield, E. Fisher, T. Fooks, A.R. Kelsall, E. Alborough, J. Wakeling, M. Parfitt, K. Milne, S. Rogers, R. Priyadharshan, J.L. Oliver, E. Davies, S. Abushal, M. Jacobs, C. Hutton, N.I. Walls, R. Thompson, C. Chigbo, S.M.A. Zaidi, M. Howard, K.C. Butter, S. Barrow, H. Little, I.U. Haq, L. Gibbons, S. Glencross, A.J. McLeod, K. Poland, C. Mulholland, A. Warke, P. Conn, G. Burns, R.N. Smith, S. Lowe, R. Kamath, H.S. Dau, J. Webster, I. Hodgins, S. Vercoe, P.C. Roome, H. Pinnock, J.R.A. Patel, A. Ali, N. Hart, R. Davies, E. Stuart, C.A. Neden, M. Danielsen, R. Heath, P. Sharma, S. Galloway, C. Hawkins, R. Oliver, M. Aylward, S. Mannion, M. Braddick, D. Edwards, A.C. Rothwell, A. Sabir, F. Choudhary, S. Khalaque, A. Wilson, S. Peters, W. Coulson, N. Roberts, A. Heer, S. Coates, B. Ward, D. Jackson, S. Walton, D. Shepherd, M. Sterry, T. Wong, M. Boon, R. Bunney, R. Haria-Shah, R.T. Baron, S. Davies, T. Schatzberger, N. Hargreaves, T. Stephenson, H. Choi, R. Batson, L. Lucraft, T. Myhill, S. Estifano, D. Geatch, J. Wilkinson, R. Veale, K. Forshaw, T. Davies, K. Zaman, P. Vinson, C. Liley, M. Bandrapalli, P. McGinty, R. Wastling, P. McEleny, A. Beattie, P. Cooke, M. Wong, J. Gunasegaram, M. Pugsley, S. Ahmad, C. A'Court, J. Ayers, J. Bennett, S. Cartwright, S. Dobson, C. Dooldeniya, A. Flynn, R. Fox, J. Goram, A. Halpin, A. Hay, P. Jacobs, L. Jeffers, L. Lomax, I. Munro, R. Muvva, M. Nadaph, K. Powell, S. Randfield, D. Redpath, R. Reed, M. Rickenbach, G. Rogers, P.B. Saunders, C. Seamark, J. Shewring, P. Simmons, H. Simper, H. Stoddart, A. Sword, N. Thomas, A. Thomson, H. Gibbs, A. Blenkhorn, B. Singh, W. Van Gaal, W. Abhayaratna, R. Lehman, P. Roberts-Thomson, J. Kilian, D. Coulshed, A. Catanchin, D. Colquhoun, H. Kiat, D. Eccleston, J. French, L. Zimmett, B. Ayres, T. Phan, P. Blombery, D. Crimmins, D. O'Donnell, A. Choi, P. Astridge, M. Arstall, N. Jepson, M. Binnekamp, A. Lee, J. Rogers, G. Starmer, P. Carroll, J. Faunt, A. Aggarwala, L. Barry, C. Batta, R. Beveridge, A. Black, M. Bonner, J. Boys, E. Buckley, M. Campo, L. Carlton, A. Connelly, B. Conway, D. Cresp, H. Dimitri, S. Dixon, M. Dolman, M. Duroux, M. Eskandari, R. Eslick, A. Ferreira-Jardim, T. Fetahovic, D. Fitzpatrick, R. Geraghty, J. Gibbs, T. Grabek, M.H. Modi, K. Hayes, M.P. Hegde, L. Hesketh, B. Hoffmann, B. Jacobson, K. Johnson, C. Juergens, I. Kassam, V. Lawlor, M. Lehman, S. Lehman, D. Leung, S. Mackay, M. MacKenzie, C. McCarthy, C. McIntosh, L. McKeon, H. Morrison, C. Mussap, J.-D. Myers, V. Nagalingam, G. Oldfield, V. O'May, J. Palmer, L. Parsons, K. Patching, T. Patching, V. Paul, M. Plotz, S. Preston, H. Rashad, M. Ratcliffe, S. Raynes, J. Rose, L. Sanders, M. Seremetkoska, H. Setio, S. Shone, P. Shrestha, C. Singh, C. Singleton, N. Stoyanov, S. Sutcliffe, K. Swaraj, J. Tarrant, S. Thompson, I.M. Tsay, M. Vorster, A. Waldman, L. Wallis, E. Wilford, K. Wong, S.J. Connolly, A. Spyropoulos, J. Eikelboom, R. Luton, M. Gupta, A.S. Pandey, S. Cheung, R. Leader, P. Beaudry, F. Ayala-Paredes, J. Berlingieri, J. Heath, G. Poirier, M. Du Preez, R. Nadeau, G. Dresser, R. Dhillon, T. Hruczkowski, B. Schweitzer, B. Coutu, P. Angaran, P. MacDonald, S. Vizel, S. Fikry, R. Parkash, A. Lavoie, J. Cha, B. Ramjattan, J. Bonet, K. Ahmad, L. Aro, T. Aves, K. Beaudry, C. Bergeron, J. Bigcanoe, N. Bignell, L. Breakwell, E. Burke, L. Carroll, B. Clarke, T. Cleveland, S. Daheb, P. Dehghani, I. Denis, Z. Djaidani, P. Dorian, S. Douglass, J. Dunnigan, A. Ewert, D. Farquhar, A. Fearon, L. Ferleyko, D. Fournier, B. Fox, M.-C. Grenier, W. Gulliver, K. Haveman, C. Hines, K. Hines, A.M. Jackson, C. Jean, G. Jethoo, R. Kahlon, S. Kelly, R. Kim, V. Korley, J. Kornder, L. Kwan, J. Largy, C. Lewis, S. Lewis, I. Mangat, R. Moor, J. Navratil, I. Neas, J. Otis, R. Otis, M. Pandey, F. Petrie, A. Pinter, M. Raines, P. Roberts, M. Robinson, G. Sas, S. Schulman, L. Snell, S. Spearson, J. Stevenson, T. Trahey, S. Wong, D. Wright, H. Ragy, A. Abd El-Aziz, S.K. Abou Seif, M.G. El Din, S. El Etriby, A. Elbahry, A. El-Etreby, M. Elkhadem, A. Katta, T. Khairy, A. Mowafy, M. Nawar, A. Ohanissian, A. Reda, M. Reda, H. Salem, N. Sami, S. Samir, M. Setiha, M. Sobhy, A. Soliman, N. Taha, M. Tawfik, E. Zaatout, D. Kettles, J. Bayat, H. Siebert, A. Horak, Y. Kelfkens, R. Garda, T. Pillay, M. Guerra, L. van Zyl, H. Theron, A. Murray, R. Louw, D. Greyling, P. Mntla, V. Ueckermann, R. Loghdey, S. Ismail, F. Ahmed, J. Engelbrecht, A. Ramdass, S. Maharajh, W. Oosthuysen, G. Angel, C. Bester, M. Booysen, C. Boshoff, C. Cannon, S. Cassimjee, C. Chami, G. Conway, A. Davids, L. de Meyer, G. Du Plessis, T. Ellis, L. Henley, M. Karsten, E. Loyd, J. Marks, L. Mavhusa, M. Mostert, A. Page, L. Rikhotso, M. Salie, J. Sasto, F. Shaik, A. Skein, L. Smith, G. Tarr, T. Tau, F. van Zyl, W. Al Mahmeed, G. Yousef, A. Agrawal, M. Nathani, M. Ibrahim, E.M. Esheiba, R. Singh, A. Naguib, M. Abu-Mahfouz, M. Al Omairi, A. Al Naeemi, R. Maruthanayagam, N. Bazargani, A. Wassef, R. Gupta, M. Khan, B. Subbaraman, A. Abdul, A. Al Mulla, S. El Bardisy, P. Haridas, S. Jadhav, K. Magdaluyo, M. Makdad, I. Maqsood, R. Mohamed, N. Sharma, R. Sharma, M. Thanzeel, S.Z. Goldhaber, R. Canosa, P. Rama, E. Blumberg, J. Garcia, P. Mullen, V. Wilson, A. Quick, K. Ferrick, W.M. Kutayli, M. Cox, M. Franco, S. Falkowski, R. Mendelson, M. Williams, S. Miller, S. Beach, A. Alfieri, T. Gutowski, I. Haque, R. Reddy, W. Ahmed, P. Delafontaine, D. Diercks, D. Theodoro, K. Remmel, M. Alberts, R. Ison, H. Noveck, P. Duffy, S. Pitta, D. Nishijima, C. Treasure, N. Asafu-Adjaye, K. Ball, M. Bartlett, M. Bentley, S. Bowers, A. Brown, A. Browne, J. Cameron-Watts, M. Canova, D. Cassidy, K. Cervellione, S. Congal, J. DePauw, A. Dickerson, M. Eley, L. Evans, S. Felpel, K. Ferdinand, D. Fielder, P. Gentry, A. Haideri, F. Hakimi, T. Harbour, E. Hartranft, B. Hawkins, M. Headlee, L. Henson, C. Herrick, T. Hicks, S. Jasinski, A. Jones, L. Jones, P. Jones, S. Karl, M. Keeling, J. Kerr, P. Knowles, J. Langdon, M. Lay, J.A. Lee, T. Lincoln, E. Malone, A. Merliss, D. Merritt, J. Minardo, B. Mooso, C. Orosco, V. Palumbo, M. Parker, T. Parrott, S. Paserchia, G. Pearl, J. Peterson, N. Pickelsimer, T. Purcell, J. Raynor, S. Raziano, C. Richard, T. Richardson, C. Robertson, A. Sage, T. Sanghera, P. Shaw, J. Shoemaker, K. Smith, B. Stephanie, A. Thatcher, H. Theobald, N. Thompson, L. Treasure, T. Tripti, C. Verdi, V. Worthy, Cardiology, ACS - Heart failure & arrhythmias, UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service de cardiologie, Sawhney, J, Kothiwale, V, Bisne, V, Durgaprasad, R, Jadhav, P, Chopda, M, Vanajakshamma, V, Meena, R, Vijayaraghavan, G, Chawla, K, Allu, J, Pieper, K, John Camm, A, Kakkar, A, Bassand, J, Fitzmaurice, D, Goldhaber, S, Goto, S, Haas, S, Hacke, W, Mantovani, L, Misselwitz, F, Turpie, A, van Eickels, M, Verheugt, F, Kayani, G, Fox, K, Gersh, B, Luciardi, H, Gibbs, H, Brodmann, M, Cools, F, Barretto, A, Connolly, S, Spyropoulos, A, Eikelboom, J, Corbalan, R, Hu, D, Jansky, P, Nielsen, J, Ragy, H, Raatikainen, P, Le Heuzey, J, Darius, H, Keltai, M, Kakkar, S, Agnelli, G, Ambrosio, G, Koretsune, Y, Sanchez Diaz, C, Ten Cate, H, Atar, D, Stepinska, J, Panchenko, E, Lim, T, Jacobson, B, Oh, S, Vinolas, X, Rosenqvist, M, Steffel, J, Angchaisuksiri, P, Oto, A, Parkhomenko, A, Al Mahmeed, W, Chen, K, Zhao, Y, Zhang, H, Chen, J, Cao, S, Wang, D, Yang, Y, Li, W, Yin, Y, Tao, G, Yang, P, Chen, Y, He, S, Wang, Y, Fu, G, Li, X, Wu, T, Cheng, X, Yan, X, Zhao, R, Chen, M, Xiong, L, Chen, P, Jiao, Y, Guo, Y, Xue, L, Wang, F, Li, H, Yang, Z, Bai, C, Chen, X, Feng, S, Fu, Q, Gao, X, Guo, W, He, R, He, X, Hu, X, Huang, X, Li, B, Li, J, Li, L, Li, Y, Liu, T, Liu, W, Liu, Y, Lu, Z, Luo, X, Ma, T, Peng, J, Sheng, X, Shi, X, Sun, Y, Tian, G, Wang, K, Wang, L, Wu, R, Xie, Q, Xu, R, Yang, J, Yang, L, Yang, Q, Ye, Y, Yu, H, Yu, J, Yu, T, Zhai, H, Zhan, Q, Zhang, G, Zhang, Q, Zhang, R, Zhang, Y, Zheng, W, Zhou, B, Zhou, Z, Zhu, X, Ravi Shankar, A, Rajput, R, Bhargava, K, Sarma, R, Srinivas, A, Roy, D, Nagamalesh, U, Kishore, R, Kulkarni, G, Chandwani, P, Pothiwala, R, Padinhare Purayil, M, Shah, S, Raghuraman, B, Vijan, V, Bantwal, G, Khan, A, Gupta, J, Kumar, S, Jain, D, Abraham, S, Adak, D, Barai, A, Begum, H, Bhattacharjee, P, Dargude, M, Davies, D, Deshpande, B, Dhakrao, P, Dhyani, V, Duhan, S, Earath, M, Ganatra, A, Giradkar, S, Jain, V, Karthikeyan, R, Kasala, L, Kaur, S, Krishnappa, S, Lawande, A, Lokesh, B, Madarkar, N, More, P, Naik, D, Prashanth, K, Rao, M, Rao, N, Sadhu, N, Shah, D, Sharma, M, Shiva, P, Singhal, S, Suresh, S, Panse, S, Kanamori, S, Yamamoto, K, Kumagai, K, Katsuda, Y, Sadamatsu, K, Toyota, F, Mizuno, Y, Misumi, I, Noguchi, H, Ando, S, Suetsugu, T, Minamoto, M, Oda, H, Shiraishi, K, Adachi, S, Chiba, K, Norita, H, Tsuruta, M, Koyanagi, T, Ando, H, Higashi, T, Okada, K, Azakami, S, Komaki, S, Kumeda, K, Murayama, T, Matsumura, J, Oba, Y, Sonoda, R, Goto, K, Minoda, K, Haraguchi, Y, Suefuji, H, Miyagi, H, Kato, H, Nakamura, T, Nandate, H, Zaitsu, R, Fujiura, Y, Yoshimura, A, Numata, H, Ogawa, J, Tatematsu, H, Kamogawa, Y, Murakami, K, Wakasa, Y, Yamasawa, M, Maekawa, H, Abe, S, Kihara, H, Tsunoda, S, Saito, K, Fudo, T, Obunai, K, Tachibana, H, Oba, I, Kuwahata, T, Higa, S, Gushiken, M, Eto, T, Yoshida, H, Ikeda, D, Ishizawa, M, Nakatsuka, M, Murata, K, Ogurusu, C, Shimoyama, M, Akutsu, M, Takamura, I, Hoshino, F, Yokota, N, Iwao, T, Tsuchida, K, Takeuchi, M, Hatori, Y, Kitami, Y, Nakamura, Y, Oyama, R, Ageta, M, Go, Y, Mishima, K, Unoki, T, Morii, S, Shiga, Y, Sumi, H, Nagatomo, T, Sanno, K, Fujisawa, K, Atsuchi, Y, Nagoshi, T, Seto, T, Tabuchi, T, Kameko, M, Nii, K, Oshiro, K, Takezawa, H, Nagano, S, Miyamoto, N, Iwaki, M, Fujii, M, Okawa, M, Abe, M, Saito, T, Mito, T, Nagao, K, Minami, J, Mita, T, Sakuma, I, Taguchi, T, Marusaki, S, Doi, H, Tanaka, M, Fujito, T, Matsuta, M, Kusumoto, T, Kakinoki, S, Ashida, K, Yoshizawa, N, Agata, J, Arasaki, O, Manita, M, Ikemura, M, Fukuoka, S, Murakami, H, Matsukawa, S, Hata, Y, Taniguchi, T, Ko, T, Kubo, H, Imamaki, M, Akiyama, M, Inagaki, M, Odakura, H, Ueda, T, Katsube, Y, Nakata, A, Watanabe, H, Techigawara, M, Igarashi, M, Taga, K, Kimura, T, Tomimoto, S, Shibuya, M, Nakano, M, Ito, K, Seo, T, Hiramitsu, S, Hosokawa, H, Hoshiai, M, Hibino, M, Miyagawa, K, Horie, H, Sugishita, N, Soma, A, Neya, K, Yoshida, T, Mizuguchi, M, Ishiguro, M, Minagawa, T, Wada, M, Mukawa, H, Okuda, F, Nagasaka, S, Abe, Y, Adachi, T, Akahane, K, Amano, T, Aoki, K, Aoyama, T, Arai, H, Arima, S, Arino, T, Asano, H, Asano, T, Azuma, J, Baba, T, Betsuyaku, T, Chibana, H, Date, H, Doiuchi, J, Emura, Y, Endo, M, Fujii, Y, Fujiki, R, Fujisawa, A, Fujisawa, Y, Fukuda, T, Fukui, T, Furukawa, N, Furukawa, T, Furumoto, W, Goto, T, Hamaoka, M, Hanazono, N, Hasegawa, K, Hatsuno, T, Hayashi, Y, Higuchi, K, Hirasawa, K, Hirayama, H, Hirose, M, Hirota, S, Honda, M, Ido, T, Iiji, O, Ikeda, H, Ikeda, K, Ikeoka, K, Imaizumi, M, Inaba, H, Inoue, T, Iseki, F, Ishihara, A, Ishioka, N, Ito, N, Iwase, T, Kakuda, H, Kamata, J, Kanai, H, Kanda, H, Kaneko, M, Kano, H, Kasai, T, Kato, T, Kato, Y, Kawada, Y, Kawai, K, Kawakami, K, Kawakami, S, Kawamoto, T, Kawano, S, Kim, J, Kira, T, Kitazawa, H, Kitazumi, H, Kito, T, Kobayashi, T, Koeda, T, Kojima, J, Komatsu, H, Komatsu, I, Koshibu, Y, Kotani, T, Kozuka, T, Kumai, Y, Kumazaki, T, Maeda, I, Maeda, K, Maruyama, Y, Matsui, S, Matsushita, K, Matsuura, Y, Mineoi, K, Mitsuhashi, H, Miura, N, Miyaguchi, S, Miyajima, S, Miyamoto, H, Miyashita, A, Miyata, S, Mizuguchi, I, Mizuno, A, Mori, T, Moriai, O, Morishita, K, Murai, O, Nagai, S, Nagata, E, Nagata, H, Nakagomi, A, Nakahara, S, Nakamura, M, Nakamura, R, Nakanishi, N, Nakayama, T, Nakazato, R, Nanke, T, Nariyama, J, Niijima, Y, Niinuma, H, Nishida, Y, Nishihata, Y, Nishino, K, Nishioka, H, Nishizawa, K, Niwa, I, Nomura, K, Nomura, S, Nozoe, M, Ogawa, T, Ohara, N, Okada, M, Okamoto, K, Okita, H, Okuyama, M, Ono, H, Ono, T, Onuki Pearce, Y, Oriso, S, Ota, A, Otaki, E, Saito, Y, Sakai, H, Sakamoto, N, Sakamoto, Y, Samejima, Y, Sasagawa, Y, Sasaguri, H, Sasaki, A, Sasaki, T, Sato, K, Sawano, M, Seki, S, Sekine, Y, Seta, Y, Sezaki, K, Shibata, N, Shiina, Y, Shimono, H, Shimoyama, Y, Shindo, T, Shinohara, H, Shinohe, R, Shinozuka, T, Shirai, T, Shiraiwa, T, Shozawa, Y, Suga, T, Sugimoto, C, Suzuki, K, Suzuki, S, Suzuki, Y, Tada, M, Taguchi, A, Takagi, T, Takagi, Y, Takahashi, K, Takahashi, S, Takai, H, Takanaka, C, Take, S, Takeda, H, Takei, K, Takenaka, K, Tana, T, Tanabe, G, Taya, K, Teragawa, H, Tohyo, S, Toru, S, Tsuchiya, Y, Tsuji, T, Tsuzaki, K, Uchiyama, H, Ueda, O, Ueyama, Y, Wakaki, N, Wakiyama, T, Washizuka, T, Watanabe, M, Yamada, T, Yamagishi, T, Yamaguchi, H, Yamamoto, T, Yamaura, M, Yamazoe, M, Yasui, K, Yokoyama, Y, Yoshida, K, Ching, C, Foo, C, Chow, J, Chen, D, Jaufeerally, F, Lee, Y, Lim, G, Lim, W, Thng, S, Yap, S, Yeo, C, Pak, H, Jang, S, Kim, D, Ryu, D, Park, S, Choi, D, Oh, Y, Cho, M, Kim, S, Jeon, H, Shin, D, Park, J, Park, H, Han, S, Sung, J, Cho, J, Nam, G, On, Y, Lim, H, Kwak, J, Cha, T, Hong, T, Yoon, J, Kim, N, Kim, K, Jung, B, Hwang, G, Kim, C, Ahn, J, An, H, Bae, H, Baek, A, Chi, W, Choi, E, Choi, H, Heo, E, Her, K, Hwang, S, Jang, E, Jang, H, Jeon, S, Jeon, Y, Jeong, H, Jung, I, Kim, H, Kim, M, Kim, Y, Lee, C, Lee, E, Lee, G, Lee, H, Lee, K, Lee, M, Lee, R, Lee, S, Lee, W, Noh, I, Park, A, Park, B, Park, M, Park, Y, Seo, S, Shim, J, Sim, J, Sohn, Y, Son, W, Son, Y, Song, H, Wi, H, Woo, J, Ye, S, Yim, K, Yoo, K, Yoon, E, Yun, S, Chawanadelert, S, Mongkolwongroj, P, Kanokphatcharakun, K, Cheewatanakornkul, S, Laksomya, T, Pattanaprichakul, S, Chantrarat, T, Rungaramsin, S, Silaruks, S, Wongcharoen, W, Siriwattana, K, Likittanasombat, K, Katekangplu, P, Boonyapisit, W, Cholsaringkarl, D, Chatlaong, B, Chattranukulchai, P, Santanakorn, Y, Hutayanon, P, Khunrong, P, Bunyapipat, T, Jai-Aue, S, Kaewsuwanna, P, Bamungpong, P, Gunaparn, S, Hongsuppinyo, S, Inphontan, R, Khattaroek, R, Khunkong, K, Kitmapawanont, U, Kongsin, C, Naratreekoon, B, Ninwaranon, S, Phangyota, J, Phrommintikul, A, Phunpinyosak, P, Pongmorakot, K, Poomiphol, S, Pornnimitthum, N, Pumprueg, S, Ratchasikaew, S, Sanit, K, Sawanyawisuth, K, Silaruks, B, Sirichai, R, Sriwichian, A, Suebjaksing, W, Sukklad, P, Suttana, T, Tangsirira, A, Thangpet, O, Tiyanon, W, Vorasettakarnkij, Y, Wisaratapong, T, Wongtheptien, W, Wutthimanop, A, Yawila, S, Altun, A, Ozdogru, I, Ozdemir, K, Yilmaz, O, Aydinlar, A, Yilmaz, M, Yeter, E, Ongen, Z, Cayli, M, Pekdemir, H, Ozdemir, M, Sucu, M, Sayin, T, Demir, M, Yorgun, H, Ersanli, M, Okuyan, E, Aras, D, Abdelrahman, H, Aktas, O, Alpay, D, Aras, F, Bireciklioglu, M, Budeyri, S, Buyukpapuc, M, Caliskan, S, Esen, M, Felekoglu, M, Genc, D, Ikitimur, B, Karaayvaz, E, Kilic Karatas, S, Okutucu, S, Ozcelik, E, Quisi, A, Sag, H, Sahiner, L, Sayin, B, Seker, T, Uzun Alkan, D, Yildirim, E, Yildirim, R, Yilmaz, F, Yuksekdag, V, Vensentini, N, Ingaramo, A, Sambadaro, G, Fernandez Caputi, V, Berman, S, Dragotto, P, Kleiban, A, Centurion, N, Giacomi, G, Ahuad Guerrero, R, Conde, D, Zapata, G, Di Paola, L, Ramos, J, Dran, R, Egido, J, Fernandez, A, Fosco, M, Sassone, S, Sinisi, V, Cartasegna, L, Berli, M, Gomez Vilamajo, O, Ferroni, F, Alaguibe, E, Alvarez D'Amelio, A, Arabetti, C, Arias, L, Belardi, J, Bergesio, L, Berli, F, Borchowiec, S, Buzzetti, C, Cabrini, R, Campisi, V, Cappi, A, Carrizo, R, Colombo Berra, F, Costabel, J, Costamagna, O, Damonte, A, De Urquiza, I, Diez, F, Eden, M, Fanuele, M, Fernandez Voena, F, Foa Torres, M, Funosas, C, Giacomi, M, Gimenez, C, Gurfinkel, E, De, L, Hansen, V, Hrabar, A, Ingratta, M, Lopez, A, Maehara, G, Maffei, L, Martinelli, A, Martinelli, C, Matkovich, J, Mautner, B, Meirino, A, Munguia, R, Navarro, A, Novas, V, Perez Prados, G, Pontoriero, J, Potito, R, Ricotti, C, Rodriguez, M, Rolandi, F, Said Palladino, M, Salinger, M, Sanziani, L, Schygiel, P, Sossich, A, Tinto, J, Tonelli, L, Tufare, A, Vallejo, M, Yunis, M, Zillo, M, Zurbrigk, F, Sobral Filho, D, Jaber, J, Armaganijan, D, Faria Neto, J, Steffens, A, Kunz Sebba Barroso de Souza, W, de Souza Neto, J, Ribeiro, J, Silveira Teixeira, M, Ferreira Rossi, P, Pires, L, Moreira, D, Moura Jorge, J, Menezes Lorga Filho, A, Bodanese, L, Westerlund Montera, M, Del Carlo, C, Da Rocha Rodrigues, T, Alves da Costa, F, Lopes, A, Lopes, R, Araujo, G, Fernandes Manenti, E, Kerr Saraiva, J, Ferreira Braga, J, Negri, A, Souto, L, Moncada, C, Bertolim Precoma, D, Roquette, F, Reis, G, Ramos Filho, R, Lanna Figueiredo, E, Vieira Botelho, R, Munhoz da Fontoura Tavares, C, Costantini Frack, C, Abdalla Saad, J, Finimundi, H, Pisani, C, Chemello, D, Pereira Martins, M, Broilo Franca, C, Alban, F, Aranha Rosito, G, de Moura Xavier Moraes Junior, J, Tumelero, R, Nigro Maia, L, Simoes de Almeida, R, do Carmo Borges, N, Gomes Ferreira, L, Agliardi, P, Alves de Oliveira Gomes, J, Araujo, V, Arruda Nakazone, M, Barbosa, T, Barroso, S, Belisario Falchetto, E, Bellotti Lopes, H, Benez Teixeira Lemos, M, Biazus, G, Borges Queiroz, L, Camazzola, F, Caporale, M, Cardoso Boscato, S, Chieza, F, Chokr, M, Clemente Mingireanov, R, Codonho Goes, N, Correa, C, Costa, M, Costantini Ortiz, C, da Silva, L, da Silva Paulitsch, F, da Silveira, J, Daros, E, de Araujo, G, Del Monaco, M, Dias, C, Dias, M, Drummond Wainstein, A, Ely Pizzato, P, Esteves, D, Fabri, P, Felix Lorenzato Fonseca, T, Fernandes, E, Fonseca, C, Frack Costantini, C, Franchin Ferraz, R, Freire, F, Gottardo, P, Guanaes, D, Guizzardi, S, Hettwer Magedanz, E, Igansi, F, Jannuzzi, F, Junior, G, Komar, D, Lino, E, Lopes, D, Lourenco da Silva Junior, O, Lustosa, E, Macagnan, A, Marinho, M, Mazzoni, M, Melo, G, Mortari, L, Mouco, O, Nanzer Vital, C, Ormundo, C, Oss Emmer, S, Palmegiani, E, Pavani, R, Pereira, L, Pereira, V, Perreira, R, Poletti, S, Quaia Fortunato, S, Queirantes, C, Ramos Pereira, N, Rech, R, Ribeiro, S, Rodrigues, A, Roesch, H, Ruaro Reichert, T, Santos, D, Santos, I, Santos, M, Seroqui, M, Silva, S, Soares, L, Spolaor, L, Stoll, C, Toazza Duda, N, Trama, L, Unterkircher, B, Valois, M, Vargas, T, Viana, T, Vicente, C, Vidal Armaganijan, L, Vieira Homem, R, Vieira Torres, L, Vila Boas, L, Villaca Guimaraes Filho, F, Eggers, G, Bugueno Gutierrez, C, Arriagada, G, Potthoff Cardenas, S, Stockins Fernandez, B, Conejeros, C, Houzvic, C, Marin Cuevas, P, Montecinos, H, Forero, A, Lanas, F, Larico Gomez, M, Charme Vilches, G, Rey, C, Astudillo, C, Aguilar, J, Campisto, Y, Lara, C, Molina, E, Munoz Oyarzon, J, Olguin, V, Vergara, M, Villan, C, Illescas Diaz, J, Leal Cantu, R, Ramos Zavala, M, Cabrera Jardines, R, Espinola Zavaleta, N, Villarreal Umana, S, Lopez Rosas, E, Llamas Esperon, G, Pozas, G, Cardona Munoz, E, Matadamas Hernandez, N, Leyva Rendon, A, Garcia Hernandez, N, de los Rios Ibarra, M, Virgen Carrillo, L, Lopez Villezca, D, Hernandez Herrera, C, Lopez Prieto, J, Gaona Rodriguez, R, Villeda Espinosa, E, Flores Martinez, D, Velasco Barcena, J, Yong, R, Rodriguez Briones, I, Leiva Pons, J, Alvarez Lopez, H, Olvera Ruiz, R, Diaz de la Vega, C, Cantu Brito, C, Chuquiure Valenzuela, E, Reyes-Sanchez, R, Bazzoni Ruiz, A, Nandayapa Flores, O, Benavides Gonzalez, M, Arriaga Nava, R, Morales Cerda, J, Fierro Fierro, O, Fajardo Campos, P, Alfaro, T, Altamirano Bellorin, S, Avena, R, Chavarria, M, Espinosa, I, Flores Silva, F, Garcia Nava, R, Godoy, K, Gonzalez Felix, E, Gonzalez Garcia, C, Gonzalez Salas, L, Guajardo, P, Hernandez Gonzalez, S, Izquierdo, T, Mancilla Ortiz, M, Martinez Vasquez, D, Mendoza, N, Morales, J, Nikitina, N, Ochoa Aybar, S, Ortiz, A, Padilla Macias, P, Perez, F, Perez Sanchez, J, Pina Toledano, S, Ramos Gonzalez, M, Rivera Ramos, C, Roa Castro, V, Romero Cardona, G, Ruiz Cornejo, M, Salinas, A, Santana, G, Sida Perez, P, Tovar Castaneda, A, Trujillo Cortes, R, Lenz, K, Drexel, H, Foechterle, J, Hagn, C, Podczeck-Schweighofer, A, Huber, K, Winkler, M, Schneeweiss, B, Gegenhuber, A, Lang, W, Eichinger-Hasenauer, S, Kaserer, P, Sykora, J, Rasch, H, Pichler, M, Schaflinger, E, Strohmer, B, Breier, R, Ebner, K, Eischer, L, Freihoff, F, Lischka-Lindner, A, Mark, T, Mirtl, A, Said, A, Stocklocker, C, Vogel, B, Vonbank, A, Wohrer, C, Zanolin, D, Paparella, G, Vandergoten, P, Parque, J, Capiau, L, Vervoort, G, Wollaert, B, Desfontaines, P, Mairesse, G, Boussy, T, Godart, P, De Wolf, A, Voet, J, Heyse, A, Hollanders, G, Anne, W, Vercammen, J, Purnode, P, Blankoff, I, Faes, D, Balthazar, Y, Beutels, M, Marechal, P, Verstraete, S, Xhaet, O, Striekwold, H, Thoeng, J, Hermans, K, Alzand, B, Ascoop, A, Banaeian, F, Barbuto, A, Billiaux, A, Blockmans, M, Bouvy, C, Brike, C, Capiau, H, Casier, T, Conde Y Bolado, A, De Cleen, D, De Coninck, M, de Vos, M, de Weerdt, N, Delforge, M, Delvigne, M, Denie, D, Derycker, K, Deweerd, E, Dormal, F, Drieghe, S, Everaert, M, Eykerman, T, Feys, E, Ghekiere, M, Gits, F, Hellemans, S, Helvasto, L, Jacobs, C, Lips, S, Mestdagh, I, Nimmegeers, J, Piamonte, V, Pollet, P, Postolache, A, Raepers, M, Raymenants, E, Richa, J, Rombouts, H, Salembier, J, Scheurwegs, C, Semeraro, O, Simons, N, Smessaert, C, Smolders, W, Stockman, I, Tahon, S, Thyssen, V, Tincani, G, Van Durme, F, Van Lier, D, Vandekerckhove, H, Vandekerckhove, Y, Vandenbroeck, D, Vandorpe, A, Vanhalst, E, Vanhauwaert, B, Vantomme, C, Vergauwen, L, Verloove, H, Vydt, T, Weyn, T, Reichert, P, Spacek, R, Machova, V, Zidkova, E, Ludka, O, Olsr, J, Kotik, L, Plocova, K, Racz, B, Ferkl, R, Hubac, J, Kotik, I, Monhart, Z, Burianova, H, Jerabek, O, Pisova, J, Petrova, I, Dedek, V, Honkova, M, Podrazil, P, Spinar, J, Vitovec, J, Novak, M, Lastuvka, J, Durdil, V, Antonova, P, Bockova, L, Bultas, J, Chlumsky, J, Dastychova, L, Drasnar, T, Honek, J, Horejsi, M, Hubacova, V, Janska, L, Kopeckova, I, Kratochvilova, R, Krcova, E, Labrova, R, Lindourkova, A, Lipoldova, J, Lubanda, H, Ludkova, A, Mahdalikova, L, Majernikova, M, Michalik, D, Potuznik, P, Prochazkova, E, Sulc, A, Sveceny, J, Valtova, M, Zidek, M, Zika, J, Nielsen, H, Husted, S, Hintze, U, Rasmussen, S, Bremmelgaard, A, Markenvard, J, Boerger, J, Solgaard, J, Simonsen, P, Loekkegaard, T, Bruun, M, Mertz, J, Dominguez, H, Skagen, K, Egstrup, K, Ibsen, H, Raymond, I, Bang-Hansen, T, Ellervik, C, Eriksen, E, Jensen, L, Jensen, M, Leth, M, Nygaard, A, Schou, M, Therkelsen, A, Tilma, J, Vesterager, K, Airaksinen, J, Arola, O, Koistinen, J, Nappila, H, Peltomaki, K, Rasanen, V, Vasankari, T, Galinier, M, Gottwalles, Y, Paganelli, F, Loiselet, P, Muller, J, Koujan, M, Marquand, A, Destrac, S, Piot, O, Delarche, N, Cebron, J, Boveda, S, Guenoun, M, Guedj-Meynier, D, Galley, D, Ohayon, J, Assouline, S, Zuber, M, Amarenco, P, Ellie, E, Kadouch, J, Fournier, P, Huberman, J, Lemaire, M, Rodier, G, Milandre, L, Vandamme, X, Sibon, I, Neau, J, Mahagne, M, Mielot, A, Bonnefoy, M, Churet, J, Navarre, V, Sellem, F, Monniot, G, Boyes, J, Doucet, B, Martelet, M, Obadia, D, Crousillat, B, Mouallem, J, Bearez, E, Nazeyrollas, P, Brugnaux, J, Fedorowsky, A, Casassus, F, Berneau, J, Chemin, F, Falvo, N, Perron, J, Poulard, J, Barreau, A, Beltra, C, Corrihons, E, Decarsin, N, Dubois, B, Ducasse, E, Giry, X, Kemmel, A, Ledure, S, Lemaire, N, Robin, F, Rosolin, N, Sanchez, D, Suissa, A, Koniger, G, Purr, J, Gerbaulet, U, Kellner, B, Kopf, A, Schafer, T, Zauzig, H, Riegel, P, Hohensee, H, Eissfeller, E, Eder, W, Rehling, G, Glatzel, D, Zutz, S, Heinz, G, Menke, H, Pustelnik, A, Sandow, P, Ludwig, N, Wiswedel, H, Wildenauer, W, Axthelm, C, Schwarz, T, Babyesiza, A, Stuchlik, G, Zimny, H, Kropp, M, Kahl, F, Caspar, A, Omankowsky, S, Lassig, T, Hartmann, H, Lehmann, G, Bindig, H, Hergdt, G, Reimer, D, Hauk, J, Dorsch, W, Dshabrailov, J, Michel, H, Rapp, K, Vormann, R, Mayer, P, Horstmeier, U, Eissing, V, Hey, H, Leuchtgens, H, Lilienweiss, V, Kolitsch, K, Schubert, C, Lauer, H, Buchner, T, Brauer, G, Kamin, S, Muller, K, Abdel-Qader, M, Baumbach, S, Ebert, H, Schwencke, C, Schellong, S, Bernhardt, P, Karolyi, L, Sievers, B, Haverkamp, W, Salbach, P, Rohnisch, J, Schoen, S, Erdle, W, Mueller, T, Mueller, H, Mitrovic, V, Babjakova, Z, Bergner, K, Boehme, S, Bonin, K, Buckert, D, Busch, F, Dichristin, U, Diez, S, Fleck, A, Flint, K, Floegel, H, Fritz, C, Frommhold, R, Gehre, J, Geyer, J, Grytzmann, A, Hahn, M, Helgert, K, Hubert, K, Kirchner-Volker, K, Klein, V, Kroll, D, Krueger, A, Lehmann, R, Mann, L, Maselli, A, Menken, G, Mikes, K, Mortan, H, Nasser, N, Nicolaus, D, Plauskat, A, Pomper, L, Quietzsch, A, Ravenhorst, C, Reichelt, C, Reimer, C, Schaefer, B, Scharrer, S, Schirmer, K, Schmidt, K, Schoene, R, Schulze, J, Schuppe, M, Simon, S, Sommer, S, Spranger, K, Talkenberger, A, Tauber, K, Tetlak, A, Toennishoff, T, Voelkel-Babyesiza, R, Voigts, B, Weiser, U, Wesendorf, S, Wildenauer, S, Wolf, T, Wurziger, J, Zak, J, Ziefle, S, Zincke, S, Vangel, S, Szalai, G, Merkely, B, Kancz, S, Boda, Z, Nagy, A, Laszlo, Z, Matoltsy, A, Gaszner, B, Polgar, P, Habon, T, Noori, E, Juhasz, G, Kanakaridisz, N, Szentpeteri, I, Juhasz, F, Vertes, A, Papp, A, May, Z, Ferenczi, J, Egyutt, M, Kis, E, Engelthaler, G, Szantai, G, Fulop, E, Gombos, P, Gulyas, D, Jen, P, Kiralyhazine Gyorke, E, Kovacs, M, Kovacsne Levang, S, Marianna, S, Radics, Z, Sydo, N, Szalo, R, Szilagyi, A, Sztanyik, F, Vandrus, B, Tiraferri, E, Santoro, R, Testa, S, Di Minno, G, Moia, M, Caimi, T, Martini, G, Tessitori, M, Cappelli, R, Poli, D, Quintavalla, R, Melone, F, Cosmi, F, Pizzini, A, Piseddu, G, Fanelli, R, Latella, C, Santi, R, Pancaldi, L, De Cristofaro, R, Palareti, G, De Blasio, A, Salerno Uriarte, J, Minetti, F, Pogliani, E, Lonati, L, Accogli, M, Ciampani, N, Malengo, S, Feola, M, Raisaro, A, Fattore, L, Grilli, P, Germini, F, Settimi, M, Alunni, M, Duranti, G, Tedeschi, L, Baglioni, G, Avanzino, G, Berardi, M, Pannacci, V, Giombolini, A, Nicoli, S, Scarponi, T, Allasia, B, Ricciarini, P, Nasorri, R, Argena, A, Bossolasco, P, Ronchini, P, Filippi, A, Tradati, F, Bulla, C, Donzelli, L, Foppa, L, Bottarelli, M, Tomasello, A, Mauric, A, Femiano, C, Reggio, R, Lillo, F, Mariani, A, Forcignano, F, Volpe, M, D'Avino, M, Bongiorni, M, Severi, S, Capucci, A, Lodigiani, C, Salomone, E, Serviddio, G, Tondo, C, Golino, P, Mazzone, C, Iacopino, S, Pengo, V, Galvani, M, Moretti, L, Ambrosino, P, Banfi, E, Biagioli, V, Bianchi, A, Boggian, G, Breschi, M, Brusorio, S, Calcagnoli, F, Campagna, G, Carpenedo, M, Ciabatta, C, Ciliberti, G, Cimmino, G, D'Arienzo, C, Di Gennaro, L, Fedele, M, Ferrini, P, Granzow, K, Guazzaloca, G, Guerra, F, Lo Buglio, A, Longo, S, Macellari, F, Mesolella, E, Mollica Poeta, E, Occhilupo, P, Oriana, V, Rangel, G, Salomone, L, Scaccianoce, A, Scarone, C, Segreti, L, Sottilota, G, Villani, R, Zecca, C, ten Cate, H, Ruiter, J, Klomps, H, Bongaerts, M, Pieterse, M, Guldener, C, Herrman, J, Lochorn, G, Lucassen, A, Adriaansen, H, The, S, Nierop, P, Hoogslag, P, Hermans, W, Groenemeijer, B, Terpstra, W, Buiks, C, Boersma, L, Boersma-Slootweg, M, Bosman, F, Bosschaert, M, Bruin, S, Danse, I, De Graaf, J, de Graauw, J, Debordes, M, Dols, S, Geerlings, F, Gorrebeeck, K, Jerzewski, A, Jetten, W, Kelderman, M, Kloosterman, T, Koomen, E, Krikken, J, Melman, P, Mulder, R, Pronk, A, Stallinga-de Vos, A, te Kaat, J, Tonino, P, Uppelschoten, B, van de Loo, R, van der Kley, T, van Leeuwen, G, van Putten, J, Westerman, L, Berge, E, Sirnes, P, Gjertsen, E, Hole, T, Erga, K, Hallaraker, A, Skjelvan, G, Ostrem, A, Ghezai, B, Svilaas, A, Christersson, P, Oien, T, Hoegh Henrichsen, S, Berg-Johansen, J, Otterstad, J, Antonsen, H, Ausen, K, Claussen, H, Dominguez, I, Jekthammer, A, Lensebraaten, A, Nilsen, V, O'Donovan, M, Ringdalen, K, Strand, S, Korzeniak, R, Gieroba, A, Biedrzycka, M, Ogorek, M, Wozakowska-Kaplon, B, Loboz-Grudzien, K, Kosior, J, Supinski, W, Kuzniar, J, Zaluska, R, Hiczkiewicz, J, Swiatkowska-Byczynska, L, Kucharski, L, Gruchala, M, Minc, P, Olszewski, M, Kania, G, Krzciuk, M, Lajkowski, Z, Ostrowska-Pomian, B, Lewczuk, J, Zinka, E, Karczmarczyk, A, Chmielnicka-Pruszczynska, M, Trusz-Gluza, M, Opolski, G, Bronisz, M, Glanowska, G, Ruszkowski, P, Jaworska, K, Sciborski, R, Okopien, B, Kukla, P, Wozniak-Skowerska, I, Galbas, K, Cymerman, K, Jurowiecki, J, Miekus, P, Myszka, W, Mazur, S, Lysek, R, Baszak, J, Rusicka-Piekarz, T, Raczak, G, Domanska, E, Nessler, J, Lesnik, J, Ambicka, M, Andrzejewski, D, Araminowicz, J, Barszcz, A, Bartkowiak, R, Bartnik, J, Basiak, M, Bekieszczuk, E, Bernat, L, Biedrzycki, L, Biernacka, A, Blaszczyk, D, Broton, E, Brzozowski, W, Brzustowska, M, Bzymek, R, Chmielowski, A, Chojnowski, P, Cichomski, R, Cieslak, K, Cieszynska, A, Curyllo, B, Czamara, M, Danilowicz-Szymanowicz, L, Dolecka, B, Drelich, L, Dudzik-Richter, B, Dybala, T, Dziuba, M, Faron, W, Figura-Chmielewska, M, Frankiewicz, A, Gadzinski, W, Gasior, E, Gosciniecka, B, Gutknecht, P, Guziewicz, M, Jackun-Podlesna, A, Jaguszewska, G, Jankielewicz, J, Jaremczuk-Kaczmarczyk, A, Jargiello-Baszak, M, Jarzebowski, A, Jaskulska-Niedziela, E, Jaworska-Drozdowska, M, Kabat, J, Kaczmarzyk-Radka, A, Kalin, K, Kaliszczak, R, Kiliszek, M, Klata, M, Kluczewski, M, Kobielusz-Gembala, I, Kochanska, E, Kociolek, D, Kolodzinska, A, Komlo, A, Konopka, A, Korczowska, E, Kowal, E, Kowalczyk, H, Kremis, E, Kruczyk, D, Krzesiak-Lodyga, A, Krzyzanowski, M, Kurdzielewicz, W, Kustrzycka-Kratochwil, D, Lesniewska-Krynska, D, Leszczynski, J, Lewicka, E, Lichota, E, Lip, K, Loboz-Rudnicka, M, Luka, J, Lysek-Jozefowicz, A, Machnikowska, M, Majewska, K, Mariankowski, R, Markiewicz, A, Mazur, M, Metzgier-Gumiela, A, Miedlar, E, Mielcarek, M, Neubauer-Geryk, J, Niedek, J, Niemirycz-Makurat, A, Nowak, A, Nowak, S, Opielowska-Nowak, B, Ozgowicz, M, Pawelska-Buczen, A, Pawlik-Rak, E, Piotrowicz, R, Ptaszynski, P, Raczynska, A, Rogowski, W, Romanek, J, Romaszkiewicz, R, Rostoff, P, Roszczyk, N, Rozewska-Furmanek, D, Rychta, J, Rzyczkowska, B, Sidor, A, Skalska, J, Smichura, M, Splawski, M, Staneta, P, Staniszewska, E, Starak-Marciniak, J, Stopyra-Poczatek, M, Sukiennik-Kujawa, M, Szafranski, J, Szalecki, P, Szczepanska, A, Szkrobka, W, Szuchnik, E, Szulowska, A, Szumczyk-Muszytowska, G, Szwoch, M, Traczyk, T, Troszczynska, M, Trzcinski, G, Tybura, S, Walasik, P, Wegrzynowska, M, Wesolowska, K, Wieczorek, W, Wierzbicka, A, Wilczewski, P, Wilgat-Szecowka, M, Wojewoda, P, Wojnowski, L, Wrobel, M, Zakutynska-Kowalczyk, K, Zyczynska-Szmon, M, Eltishcheva, V, Libis, R, Tereshchenko, S, Popov, S, Kamalov, G, Belenky, D, Zateyshchikova, A, Kropacheva, E, Kolesnikova, A, Nikolaev, K, Egorova, L, Khokhlov, A, Yakupov, E, Poltavskaya, M, Zateyshchikov, D, Drapkina, O, Vishnevsky, A, Barbarash, O, Miller, O, Aleksandrova, E, Chizhov, P, Sergeev, M, Shutemova, E, Mazur, E, Zrazhevskiy, K, Novikova, T, Kostenko, V, Moiseeva, Y, Polkanova, E, Sobolev, K, Rossovskaya, M, Zubeeva, G, Shapovalova, Y, Nagibovich, O, Edin, A, Agakhanyan, A, Batalov, R, Belenkova, Y, Bitakova, F, Chugunnaya, S, Dumikyan, A, Erofeeva, S, Gorbunova, E, Gorshkova, T, Gubanov, A, Gurmach, M, Ivanova, Y, Kolesova, T, Konyushenko, D, Korneeva, O, Kropova, O, Kuchuk, P, Kungurtseva, O, Kupriyanova, T, Kurylo, B, Kuvanova, M, Lebedeva, O, Lileeva, E, Machilskaya, O, Medvedeva, T, Monako, G, Motylev, I, Nagibovich, G, Novikova, E, Orlov, Y, Osmolovskaya, Y, Ovsannikova, A, Platonov, D, Rachkova, S, Sinitsina, O, Speshilova, S, Suslova, O, Ushakov, A, Volodicheva, O, Zemlianskaia, O, Zhirov, I, Zhuravleva, E, Zotova, I, Alvarez Garcia, P, Lopez Fernandez, M, Tercedor, L, Tranche Iparraguirre, S, Toran Monserrat, P, Marquez Contreras, E, Isart Rafecas, J, Motero Carrasco, J, Garcia Pavia, P, Gomez Pajuelo, C, Moro Serrano, C, Iglesias Alonso, L, Grande Ruiz, A, Merce Klein, J, Gonzalez Juanatey, J, Baron Esquivias, G, Monte Collado, I, Palacin Piquero, H, Brotons Cuixart, C, Rodriguez Morato, M, Bayo I Llibre, J, Corros Vicente, C, Vida Gutierrez, M, Epelde Gonzalo, F, Almeida Fernandez, C, Del Val Plana, N, Escriva Montserrat, E, Montero Alia, J, Barreda Gonzalez, M, Moleiro Oliva, M, Iglesias Sanmartin, J, Jimenez Gonzalez, M, Rodriguez Alvarez, M, Herreros Melenchon, J, Ripoll Vera, T, Ridocci Soriano, F, Garcia Riesco, L, Marco Macian, M, Quiles Granado, J, Jimenez Navarro, M, Cosin Sales, J, Vaquer Perez, J, Vazquez Caamano, M, Arcocha Torres, M, Marcos Gomez, G, Iniguez Romo, A, Prieto Diaz, M, Alonso, C, Alvarez, D, Alvarez, M, Amaro, M, Andere, N, Aracil Villar, J, Armitano Ochoa, R, Austria, A, Barbeira, S, Barraquer Feu, E, Bartes, A, Becerra Munoz, V, Bermudez Jimenez, F, Branjovich Tijuan, A, Cabeza Ramirez, J, Cabrera Ramos, M, Calvo Martinez, E, Campo Moreno, M, Cancho Corchado, G, Casanova Gil, M, Castillo Orive, M, Castro Fernandez, D, Cebollada del Misterio, M, Codinachs Alsina, R, Cortada Cabrera, A, Costa Pinto Prego de Faria, J, Costas, S, Cotilla Marco, M, Dachs, M, Diaz Lopez, C, Domenech Borras, A, Elorriaga Madariaga, A, Espallargas, A, Fernandez, M, Fernandez Escobar, E, Fernandez Mas, E, Ferrer, A, Fosch, J, Garcia Bermudez, M, Garcia Millan, V, Gavira Saenz, M, Gines Garcia, C, Gomez, C, Gomez Perez, Y, Gonzales Segovia, A, Gonzalez, P, Grigorian, L, Guerrero Molina, A, Del, C, Herrero Maeso, B, Hevia Rodriguez, E, Iglesias Garcia, A, Jimenez Fernandez, M, Jimeno Besa, B, Juan Salvadores, P, Lage Bouzamayor, M, Lasuncion, I, Lezcano Gort, L, Llobet Molina, M, Lopez, M, Manzanal Rey, A, Mara Guerra, J, Marcus, S, Martin Vila, A, Martinez Mena, M, Mazon, P, Mendez Zurita, F, Millan, G, Molina, M, Montero Alia, P, Montes, D, Moure Gonzalez, M, Munoz Munoz, R, Negrete Palma, A, Orellana Figueroa, H, Ortega, V, Ortiz Cortes, C, Otero Tomera, D, Palomo Merchan, N, Pareja Ibar, I, Pena Garcia, E, Pereda Armayor, M, Perez Carasa, M, Prieto, I, Quintern, V, Renom, R, Rincon Diaz, L, Rios, V, Riquelme Sola, L, Rivera, R, Robiro Robiro, X, Roca, M, Roca Saumell, C, Rodrigo, C, Rodriguez, E, Rodriguez Garcia, M, Saez Jimenez, S, Sanchez Calderon, P, Sanchez Mendez, L, Sanchez Parra, S, Santolaya, C, Senan Sanz, M, Seoane Blanco, A, Serralvo, E, Sierra, N, Simon Valero, C, Sorribes Lopez, J, Teixido Fontanillas, M, Terns Riera, M, Tobajas, G, Torres, C, Torres Marques, J, Ubeda Pastor, M, Wirdby, A, Linden, J, Henriksson, K, Elmersson, M, Egilsson, A, Borjesson, U, Svard, G, Liu, B, Lindh, A, Olsson, L, Gustavsson, M, Andersson, L, Benson, L, Bothin, C, Hajimirsadeghi, A, Kadir, K, Ericsson, M, Ohlsson, A, Lindvall, H, Svensson, P, Thorne, K, Handel, H, Platonov, P, Eriksson, B, Timberg, I, Romberg, K, Crisby, M, Karlsson, J, Jensen, S, Andersson, A, Malmqvist, L, Martinsson, B, Bernsten, F, Engdahl, J, Thulin, J, Hot-Bjelac, A, Stalby, P, Aaroe, H, Ahbeck, E, Ahlmark, H, Al-Khalili, F, Bonkowski, G, Dzeletovic, S, Ekstrand, A, Eriksson, G, Floren, K, Grassjo, C, Hahn, S, Jaensson, P, Jansson, B, Jansson, J, Kangert, R, Koch, A, Kusiak, D, Lettenstrom, A, Lindberg, A, Lindholm, C, Mannermyr, A, Mansson, K, Millborg, M, Nilsson, C, Ohlin, A, Olofsson, A, Osberg, A, Pedersen, A, Risbecker, K, Rosenberg, K, Samuelsson, J, Shayesteh, M, Skoglund, K, Stjernberg, M, Thorsen, C, Beer, J, Debrunner, J, Amstutz, D, Bruegger, J, Elise, G, Grau, A, Guinand, A, Henriette, I, Saga, E, Winnik, S, Rudyk, I, Tseluyko, V, Karpenko, O, Zhurba, S, Kraiz, I, Kupnovytska, I, Serediuk, N, Mostovoy, Y, Ushakov, O, Koval, O, Kovalskyi, I, Svyshchenko, Y, Sychov, O, Stanislavchuk, M, Kraydashenko, O, Yagensky, A, Tykhonova, S, Fushtey, I, Belegai, R, Berko, G, Burdeuna, L, Chabanna, O, Daniuk, I, Ivanov, A, Kamenska, E, Kaplan, P, Khyzhnyak, O, Kizim, S, Matova, O, Medentseva, O, Mochonyi, V, Mospan, M, Nemtsova, V, Ovdiienko, T, Palamarchuk, O, Pavelko, M, Petrovskyy, R, Plevak, D, Proshak, O, Pyvovar, S, Rasputina, L, Romanenko, O, Romanova, O, Sapatyi, A, Shumakov, O, Stets, R, Todoriuk, L, Varenov, V, Chauhan, N, Goodwin, D, Saunders, P, Evans, R, Leese, J, Jhittay, P, Ross, A, Kainth, M, Pickavance, G, Mcdonnell, J, Williams, A, Gooding, T, Wagner, H, Suryani, S, Singal, A, Sircar, S, Bilas, R, Hutchinson, P, Wakeman, A, Stokes, M, Paul, N, Aziz, M, Ramesh, C, Wilson, P, Franklin, S, Fairhead, S, Thompson, J, St Joseph, V, Taylor, G, Tragen, D, Seamark, D, Paul, C, Richardson, M, Jefferies, A, Sharp, H, Jones, H, Giles, C, Page, M, Oginni, O, Aldegather, J, Wetherwell, S, Lumb, W, Evans, P, Scouller, F, Macey, N, Stipp, Y, West, R, Thurston, S, Wadeson, P, Matthews, J, Pandya, P, Gallagher, A, Railton, T, Sinha, B, Russell, D, Davies, J, Ainsworth, P, Jones, C, Weeks, P, Eden, J, Kernick, D, Murdoch, W, Lumley, L, Patel, R, Wong, S, Saigol, M, Ladha, K, Douglas, K, Cumberlidge, D, Bradshaw, C, Van Zon, G, Jones, K, Thomas, M, Watson, E, Sarai, B, Ahmad, N, Willcock, W, Cairns, J, Sathananthan, S, de Kare-Silver, N, Gilliland, A, Strieder, E, Howitt, A, Vishwanathan, B, Bird, N, Gray, D, Clark, M, Bisatt, J, Litchfield, J, Fisher, E, Fooks, T, Kelsall, A, Alborough, E, Wakeling, J, Parfitt, M, Milne, K, Rogers, S, Priyadharshan, R, Oliver, J, Davies, E, Abushal, S, Jacobs, M, Hutton, C, Walls, N, Thompson, R, Chigbo, C, Zaidi, S, Howard, M, Butter, K, Barrow, S, Little, H, Haq, I, Gibbons, L, Glencross, S, Mcleod, A, Poland, K, Mulholland, C, Warke, A, Conn, P, Burns, G, Smith, R, Lowe, S, Kamath, R, Dau, H, Webster, J, Hodgins, I, Vercoe, S, Roome, P, Pinnock, H, Patel, J, Ali, A, Hart, N, Davies, R, Stuart, E, Neden, C, Danielsen, M, Heath, R, Sharma, P, Galloway, S, Hawkins, C, Oliver, R, Aylward, M, Mannion, S, Braddick, M, Edwards, D, Rothwell, A, Sabir, A, Choudhary, F, Khalaque, S, Wilson, A, Peters, S, Coulson, W, Roberts, N, Heer, A, Coates, S, Ward, B, Jackson, D, Walton, S, Shepherd, D, Sterry, M, Wong, T, Boon, M, Bunney, R, Haria-Shah, R, Baron, R, Davies, S, Schatzberger, T, Hargreaves, N, Stephenson, T, Batson, R, Lucraft, L, Myhill, T, Estifano, S, Geatch, D, Wilkinson, J, Veale, R, Forshaw, K, Davies, T, Zaman, K, Vinson, P, Liley, C, Bandrapalli, M, Mcginty, P, Wastling, R, Mceleny, P, Beattie, A, Cooke, P, Wong, M, Gunasegaram, J, Pugsley, M, Ahmad, S, A'Court, C, Ayers, J, Bennett, J, Cartwright, S, Dobson, S, Dooldeniya, C, Flynn, A, Fox, R, Goram, J, Halpin, A, Hay, A, Jacobs, P, Jeffers, L, Lomax, L, Munro, I, Muvva, R, Nadaph, M, Powell, K, Randfield, S, Redpath, D, Reed, R, Rickenbach, M, Rogers, G, Seamark, C, Shewring, J, Simmons, P, Simper, H, Stoddart, H, Sword, A, Thomas, N, Thomson, A, Blenkhorn, A, Singh, B, Van Gaal, W, Abhayaratna, W, Lehman, R, Roberts-Thomson, P, Kilian, J, Coulshed, D, Catanchin, A, Colquhoun, D, Kiat, H, Eccleston, D, French, J, Zimmett, L, Ayres, B, Phan, T, Blombery, P, Crimmins, D, O'Donnell, D, Choi, A, Astridge, P, Arstall, M, Jepson, N, Binnekamp, M, Lee, A, Rogers, J, Starmer, G, Carroll, P, Faunt, J, Aggarwala, A, Barry, L, Batta, C, Beveridge, R, Black, A, Bonner, M, Boys, J, Buckley, E, Campo, M, Carlton, L, Connelly, A, Conway, B, Cresp, D, Dimitri, H, Dixon, S, Dolman, M, Duroux, M, Eskandari, M, Eslick, R, Ferreira-Jardim, A, Fetahovic, T, Fitzpatrick, D, Geraghty, R, Gibbs, J, Grabek, T, Modi, M, Hayes, K, Hegde, M, Hesketh, L, Hoffmann, B, Johnson, K, Juergens, C, Kassam, I, Lawlor, V, Lehman, M, Lehman, S, Leung, D, Mackay, S, Mackenzie, M, Mccarthy, C, Mcintosh, C, Mckeon, L, Morrison, H, Mussap, C, Myers, J, Nagalingam, V, Oldfield, G, O'May, V, Palmer, J, Parsons, L, Patching, K, Patching, T, Paul, V, Plotz, M, Preston, S, Rashad, H, Ratcliffe, M, Raynes, S, Rose, J, Sanders, L, Seremetkoska, M, Setio, H, Shone, S, Shrestha, P, Singh, C, Singleton, C, Stoyanov, N, Sutcliffe, S, Swaraj, K, Tarrant, J, Thompson, S, Tsay, I, Vorster, M, Waldman, A, Wallis, L, Wilford, E, Wong, K, Luton, R, Gupta, M, Pandey, A, Cheung, S, Leader, R, Beaudry, P, Ayala-Paredes, F, Berlingieri, J, Heath, J, Poirier, G, Du Preez, M, Nadeau, R, Dresser, G, Dhillon, R, Hruczkowski, T, Schweitzer, B, Coutu, B, Angaran, P, Macdonald, P, Vizel, S, Fikry, S, Parkash, R, Lavoie, A, Cha, J, Ramjattan, B, Bonet, J, Ahmad, K, Aro, L, Aves, T, Beaudry, K, Bergeron, C, Bigcanoe, J, Bignell, N, Breakwell, L, Burke, E, Carroll, L, Clarke, B, Cleveland, T, Daheb, S, Dehghani, P, Denis, I, Djaidani, Z, Dorian, P, Douglass, S, Dunnigan, J, Ewert, A, Farquhar, D, Fearon, A, Ferleyko, L, Fournier, D, Fox, B, Grenier, M, Gulliver, W, Haveman, K, Hines, C, Hines, K, Jackson, A, Jean, C, Jethoo, G, Kahlon, R, Kelly, S, Kim, R, Korley, V, Kornder, J, Kwan, L, Largy, J, Lewis, C, Lewis, S, Mangat, I, Moor, R, Navratil, J, Neas, I, Otis, J, Otis, R, Pandey, M, Petrie, F, Pinter, A, Raines, M, Roberts, P, Robinson, M, Sas, G, Schulman, S, Snell, L, Spearson, S, Stevenson, J, Trahey, T, Wright, D, Abd El-Aziz, A, Abou Seif, S, El Din, M, El Etriby, S, Elbahry, A, El-Etreby, A, Elkhadem, M, Katta, A, Khairy, T, Mowafy, A, Nawar, M, Ohanissian, A, Reda, A, Reda, M, Salem, H, Sami, N, Samir, S, Setiha, M, Sobhy, M, Soliman, A, Taha, N, Tawfik, M, Zaatout, E, Kettles, D, Bayat, J, Siebert, H, Horak, A, Kelfkens, Y, Garda, R, Pillay, T, Guerra, M, van Zyl, L, Theron, H, Murray, A, Louw, R, Greyling, D, Mntla, P, Ueckermann, V, Loghdey, R, Ismail, S, Ahmed, F, Engelbrecht, J, Ramdass, A, Maharajh, S, Oosthuysen, W, Angel, G, Bester, C, Booysen, M, Boshoff, C, Cannon, C, Cassimjee, S, Chami, C, Conway, G, Davids, A, de Meyer, L, Du Plessis, G, Ellis, T, Henley, L, Karsten, M, Loyd, E, Marks, J, Mavhusa, L, Mostert, M, Page, A, Rikhotso, L, Salie, M, Sasto, J, Shaik, F, Skein, A, Smith, L, Tarr, G, Tau, T, van Zyl, F, Yousef, G, Agrawal, A, Nathani, M, Ibrahim, M, Esheiba, E, Singh, R, Naguib, A, Abu-Mahfouz, M, Al Omairi, M, Al Naeemi, A, Maruthanayagam, R, Bazargani, N, Wassef, A, Gupta, R, Khan, M, Subbaraman, B, Abdul, A, Al Mulla, A, El Bardisy, S, Haridas, P, Jadhav, S, Magdaluyo, K, Makdad, M, Maqsood, I, Mohamed, R, Sharma, N, Sharma, R, Thanzeel, M, Canosa, R, Rama, P, Blumberg, E, Garcia, J, Mullen, P, Wilson, V, Quick, A, Ferrick, K, Kutayli, W, Cox, M, Franco, M, Falkowski, S, Mendelson, R, Williams, M, Miller, S, Beach, S, Alfieri, A, Gutowski, T, Haque, I, Reddy, R, Ahmed, W, Delafontaine, P, Diercks, D, Theodoro, D, Remmel, K, Alberts, M, Ison, R, Noveck, H, Duffy, P, Pitta, S, Nishijima, D, Treasure, C, Asafu-Adjaye, N, Ball, K, Bartlett, M, Bentley, M, Bowers, S, Brown, A, Browne, A, Cameron-Watts, J, Canova, M, Cassidy, D, Cervellione, K, Congal, S, Depauw, J, Dickerson, A, Eley, M, Evans, L, Felpel, S, Ferdinand, K, Fielder, D, Gentry, P, Haideri, A, Hakimi, F, Harbour, T, Hartranft, E, Hawkins, B, Headlee, M, Henson, L, Herrick, C, Hicks, T, Jasinski, S, Jones, A, Jones, L, Jones, P, Karl, S, Keeling, M, Kerr, J, Knowles, P, Langdon, J, Lay, M, Lee, J, Lincoln, T, Malone, E, Merliss, A, Merritt, D, Minardo, J, Mooso, B, Orosco, C, Palumbo, V, Parker, M, Parrott, T, Paserchia, S, Pearl, G, Peterson, J, Pickelsimer, N, Purcell, T, Raynor, J, Raziano, S, Richard, C, Richardson, T, Robertson, C, Sage, A, Sanghera, T, Shaw, P, Shoemaker, J, Smith, K, Stephanie, B, Thatcher, A, Theobald, H, Thompson, N, Treasure, L, Tripti, T, Verdi, C, Worthy, V, Sawhney, Jitendra PS., Kothiwale, Veerappa A., Bisne, Vika, Durgaprasad, Rajashekhar, Jadhav, Praveen, Chopda, Manoj, Vanajakshamma, Velam, Meena, Ramdhan, Vijayaraghavan, Govindan, Chawla, Kamaldeep, Allu, Jagan, Pieper, Karen S., John Camm, A., Kakkar, Ajay K., Bassand, Jean-Pierre, Fitzmaurice, David A., Goldhaber, Samuel Z., Goto, Shinya, Haas, Sylvia, Hacke, Werner, Mantovani, Lorenzo G., Misselwitz, Frank, Turpie, Alexander G. G., van Eickels, Martin, Verheugt, Freek W. A., Kayani, Gloria, Fox, Keith A. A., Gersh, Bernard J., Luciardi, Hector Luca, Gibbs, Harry, Brodmann, Marianne, Cools, Frank, Barretto, Antonio Carlos Pereira, Connolly, Stuart J., Spyropoulos, Alex, Eikelboom, John, Corbalan, Ramon, Hu, Dayi, Jansky, Petr, Nielsen, Jørn Dalsgaard, Ragy, Hany, Raatikainen, Pekka, Le Heuzey, Jean-Yve, Darius, Harald, Keltai, Matya, Kakkar, Sanjay, Sawhney, Jitendra Pal Singh, Agnelli, Giancarlo, Ambrosio, Giuseppe, Koretsune, Yukihiro, Sánchez Díaz, Carlos Jerje, Ten Cate, Hugo, Atar, Dan, Stepinska, Janina, Panchenko, Elizaveta, Lim, Toon Wei, Jacobson, Barry, Oh, Seil, Viñolas, Xavier, Rosenqvist, Marten, Steffel, Jan, Angchaisuksiri, Pantep, Oto, Ali, Parkhomenko, Alex, Al Mahmeed, Wael, Fitzmaurice, David, Hu, D. Y., Chen, K. N., Zhao, Y. S., Zhang, H. Q., Chen, J. Z., Cao, S. P., Wang, D. W., Yang, Y. J., Li, W. H., Yin, Y. H., Tao, G. Z., Yang, P., Chen, Y. M., He, S. H., Wang, Ying, Wang, Yong, Fu, G. S., Li, X., Wu, T. G., Cheng, X. S., Yan, X. W., Zhao, R. P., Chen, M. S., Xiong, L. G., Chen, P., Jiao, Y., Guo, Y., Xue, L., Wang, F. Z., Li, H., Yang, Z. M., Bai, C. L., Chen, J., Chen, J. Y., Chen, X., Feng, S., Fu, Q. H., Gao, X. J., Guo, W. N., He, R. H., He, X. A., Hu, X. S., Huang, X. F., Li, B., Li, J., Li, L., Li, Y. H., Liu, T. T., Liu, W. L., Liu, Y. Y., Lu, Z. C., Luo, X. L., Ma, T. Y., Peng, J. Q., Sheng, X., Shi, X. J., Sun, Y. H., Tian, G., Wang, K., Wang, L., Wu, R. N., Xie, Q., Xu, R. Y., Yang, J. S., Yang, L. L., Yang, Q., Ye, Y., Yu, H. Y., Yu, J. H., Yu, T., Zhai, H., Zhan, Q., Zhang, G. S., Zhang, Q., Zhang, R., Zhang, Y., Zheng, W. Y., Zhou, B., Zhou, Z. H., Zhu, X. Y., Kakkar, S., Sawhney, J. P. S., Jadhav, P., Durgaprasad, R., Ravi Shankar, A. G., Rajput, R. K., Bhargava, K., Sarma, R., Srinivas, A., Roy, D., Nagamalesh, U. M., Chopda, M., Kishore, R., Kulkarni, G., Chandwani, P., Pothiwala, R. A., Padinhare Purayil, M., Shah, S., Chawla, K., Kothiwale, V. A., Raghuraman, B., Vijayaraghavan, G., Vijan, V. M., Bantwal, G., Bisne, V., Khan, A., Gupta, J. B., Kumar, S., Jain, D., Abraham, S., Adak, D., Barai, A., Begum, H., Bhattacharjee, P., Dargude, M., Davies, D., Deshpande, B., Dhakrao, P., Dhyani, V., Duhan, S., Earath, M., Ganatra, A., Giradkar, S., Jain, V., Karthikeyan, R., Kasala, L., Kaur, S., Krishnappa, S., Lawande, A., Lokesh, B., Madarkar, N., Meena, R., More, P., Naik, D., Prashanth, K., Rao, M., Rao, N. M., Sadhu, N., Shah, D., Sharma, M., Shiva, P., Singhal, S., Suresh, S., Vanajakshamma, V., Panse, S. G., Koretsune, Y., Kanamori, S., Yamamoto, K., Kumagai, K., Katsuda, Y., Sadamatsu, K., Toyota, F., Mizuno, Y., Misumi, I., Noguchi, H., Ando, S., Suetsugu, T., Minamoto, M., Oda, Hiroshi, Shiraishi, K., Adachi, S., Chiba, K., Norita, H., Tsuruta, M., Koyanagi, T., Ando, H., Higashi, T., Okada, K., Azakami, S., Komaki, S., Kumeda, K., Murayama, T., Matsumura, J., Oba, Y., Sonoda, R., Goto, K., Minoda, K., Haraguchi, Y., Suefuji, H., Miyagi, H., Kato, H., Nakamura, Tadashi, Nakamura, Tsugihiro, Nandate, H., Zaitsu, R., Fujiura, Yoshihisa, Yoshimura, A., Numata, H., Ogawa, J., Tatematsu, H., Kamogawa, Y., Murakami, K., Wakasa, Y., Yamasawa, M., Maekawa, H., Abe, S., Kihara, H., Tsunoda, S., Saito, Katsumi, Saito, Kazuyuki, Fudo, T., Obunai, K., Tachibana, H., Oba, I., Kuwahata, T., Higa, S., Gushiken, M., Eto, T., Yoshida, H., Ikeda, D., Fujiura, Yoshitake, Ishizawa, M., Nakatsuka, M., Murata, K., Ogurusu, C., Shimoyama, M., Akutsu, M., Takamura, I., Hoshino, F., Yokota, N., Iwao, T., Tsuchida, K., Takeuchi, M., Hatori, Y., Kitami, Y., Nakamura, Yoichi, Oyama, R., Ageta, M., Oda, Hiroyuki, Go, Y., Mishima, K., Unoki, T., Morii, S., Shiga, Yuhei, Sumi, H., Nagatomo, T., Sanno, K., Fujisawa, K., Atsuchi, Y., Nagoshi, T., Seto, T., Tabuchi, T., Kameko, M., Nii, K., Oshiro, K., Takezawa, H., Nagano, S., Miyamoto, N., Iwaki, M., Nakamura, Yuichiro, Fujii, M., Okawa, M., Abe, Masahiko, Abe, Masatake, Abe, Mitsunori, Saito, T., Mito, T., Nagao, K., Minami, J., Mita, T., Sakuma, I., Taguchi, T., Marusaki, S., Doi, H., Tanaka, M., Fujito, T., Matsuta, M., Kusumoto, T., Kakinoki, S., Ashida, K., Yoshizawa, N., Agata, J., Arasaki, O., Manita, M., Ikemura, M., Fukuoka, S., Murakami, H., Matsukawa, S., Hata, Y., Taniguchi, T., Ko, T., Kubo, H., Imamaki, M., Akiyama, M., Inagaki, M., Odakura, H., Ueda, T., Katsube, Y., Nakata, A., Watanabe, H., Techigawara, M., Igarashi, M., Taga, K., Kimura, T., Tomimoto, S., Shibuya, M., Nakano, M., Ito, K., Seo, T., Hiramitsu, S., Hosokawa, H., Hoshiai, M., Hibino, M., Miyagawa, K., Horie, Hajime, Sugishita, N., Shiga, Yukio, Soma, A., Neya, K., Yoshida, Tetsuro, Yoshida, Tomoki, Mizuguchi, M., Ishiguro, M., Minagawa, T., Wada, M., Mukawa, H., Okuda, F., Nagasaka, S., Abe, Y., Adachi, Sen, Adachi, Susumu, Adachi, T., Akahane, K., Amano, T., Aoki, K., Aoyama, T., Arai, H., Arima, S., Arino, T., Asano, H., Asano, T., Azuma, J., Baba, T., Betsuyaku, T., Chibana, H., Date, H., Doiuchi, J., Emura, Y., Endo, M., Fujii, Y., Fujiki, R., Fujisawa, A., Fujisawa, Y., Fukuda, T., Fukui, T., Furukawa, N., Furukawa, T., Furumoto, W., Goto, T., Hamaoka, M., Hanazono, N., Hasegawa, K., Hatsuno, T., Hayashi, Y., Higuchi, K., Hirasawa, K., Hirayama, H., Hirose, M., Hirota, S., Honda, M., Horie, Hideki, Ido, T., Iiji, O., Ikeda, H., Ikeda, K., Ikeoka, K., Imaizumi, M., Inaba, H., Inoue, T., Iseki, F., Ishihara, A., Ishioka, N., Ito, N., Iwase, T., Kakuda, H., Kamata, J., Kanai, H., Kanda, H., Kaneko, M., Kano, H., Kasai, T., Kato, T., Kato, Y., Kawada, Y., Kawai, K., Kawakami, K., Kawakami, S., Kawamoto, T., Kawano, S., Kim, J., Kira, T., Kitazawa, H., Kitazumi, H., Kito, T., Kobayashi, T., Koeda, T., Kojima, J., Komatsu, H., Komatsu, I., Koshibu, Y., Kotani, T., Kozuka, T., Kumai, Y., Kumazaki, T., Maeda, I., Maeda, K., Maruyama, Y., Matsui, S., Matsushita, K., Matsuura, Y., Mineoi, K., Mitsuhashi, H., Miura, N., Miyaguchi, S., Miyajima, S., Miyamoto, H., Miyashita, A., Miyata, S., Mizuguchi, I., Mizuno, A., Mori, T., Moriai, O., Morishita, K., Murai, O., Nagai, Sho, Nagai, Shunichi, Nagata, E., Nagata, H., Nakagomi, A., Nakahara, S., Nakamura, M., Nakamura, R., Nakanishi, N., Nakayama, T., Nakazato, R., Nanke, T., Nariyama, J., Niijima, Y., Niinuma, H., Nishida, Y., Nishihata, Y., Nishino, K., Nishioka, H., Nishizawa, K., Niwa, I., Nomura, K., Nomura, S., Nozoe, M., Ogawa, T., Ohara, N., Okada, M., Okamoto, K., Okita, H., Okuyama, M., Ono, H., Ono, T., Onuki Pearce, Y., Oriso, S., Ota, A., Otaki, E., Saito, Y., Sakai, H., Sakamoto, N., Sakamoto, Y., Samejima, Y., Sasagawa, Y., Sasaguri, H., Sasaki, A., Sasaki, T., Sato, Kazuki, Sato, Kiyoharu, Sawano, M., Seki, S., Sekine, Y., Seta, Y., Sezaki, K., Shibata, N., Shiina, Y., Shimono, H., Shimoyama, Y., Shindo, T., Shinohara, H., Shinohe, R., Shinozuka, T., Shirai, T., Shiraiwa, T., Shozawa, Y., Suga, T., Sugimoto, C., Suzuki, Kazuo, Suzuki, Keita, Suzuki, Shu, Suzuki, Shunji, Suzuki, Susumu, Suzuki, Y., Tada, M., Taguchi, A., Takagi, T., Takagi, Y., Takahashi, K., Takahashi, S., Takai, H., Takanaka, C., Take, S., Takeda, H., Takei, K., Takenaka, K., Tana, T., Tanabe, G., Taya, K., Teragawa, H., Tohyo, S., Toru, S., Tsuchiya, Y., Tsuji, T., Tsuzaki, K., Uchiyama, H., Ueda, O., Ueyama, Y., Wakaki, N., Wakiyama, T., Washizuka, T., Watanabe, M., Yamada, T., Yamagishi, T., Yamaguchi, H., Yamamoto, Kenichi, Yamamoto, Kentaro, Yamamoto, Kunihiko, Yamamoto, T., Yamaura, M., Yamazoe, M., Yasui, K., Yokoyama, Y., Yoshida, K., Lim, T. W., Ching, C. K., Foo, C. G., Chow, J. H., Chen, D. D., Jaufeerally, F. R., Lee, Y. M., Lim, G., Lim, W. T., Thng, S., Yap, S. Y., Yeo, C., Oh, S., Pak, H. N., Kim, J. -B., Kim, J. H., Jang, S. -W., Kim, D. H., Ryu, D. R., Park, S. W., Kim, D. -K., Choi, D. J., Oh, Y. S., Cho, M. -C., Kim, S. -H., Jeon, H. -K., Shin, D. -G., Park, J. S., Park, H. K., Han, S. -J., Sung, J. H., Cho, J. -G., Nam, G. -B., On, Y. K., Lim, H. E., Kwak, J. J., Cha, T. -J., Hong, T. J., Park, S. H., Yoon, J. H., Kim, N. -H., Kim, K. -S., Jung, B. C., Hwang, G. -S., Kim, C. -J., Kim, D. B., Ahn, J. J., An, H. J., Bae, H., Baek, A. L., Chi, W. J., Choi, E. A., Choi, E. H., Choi, H. K., Choi, H. S., Han, S., Heo, E. S., Her, K. O., Hwang, S. W., Jang, E. M., Jang, H. -S., Jang, S., Jeon, H. -G., Jeon, S. R., Jeon, Y. R., Jeong, H. K., Jung, I. -A., Kim, Hyeon Jeong, Kim, Hyun Ju, Kim, Ji Seon, Kim, Jung Sook, Kim, J. A., Kim, K. T., Kim, M. S., Kim, Sang Hee, Kim, Sang Hyun, Kim, Y. -I., Lee, C. S., Lee, E. H., Lee, G. H., Lee, H. Y., Lee, H. -Y., Lee, K. H., Lee, K. R., Lee, M. S., Lee, M. -Y., Lee, R. W., Lee, S. E., Lee, S. H., Lee, S., Lee, W. Y., Noh, I. K., Park, A. R., Park, B. R., Park, H. N., Park, J. H., Park, M., Park, Y., Seo, S. -Y., Shim, J., Sim, J. H., Sohn, Y. M., Son, W. S., Son, Y. S., Song, H. J., Wi, H. K., Woo, J. J., Ye, S., Yim, K. H., Yoo, K. M., Yoon, E. J., Yun, S. Y., Angchaisuksiri, P., Chawanadelert, S., Mongkolwongroj, P., Kanokphatcharakun, K., Cheewatanakornkul, S., Laksomya, T., Pattanaprichakul, S., Chantrarat, T., Rungaramsin, S., Silaruks, S., Wongcharoen, W., Siriwattana, K., Likittanasombat, K., Katekangplu, P., Boonyapisit, W., Cholsaringkarl, D., Chatlaong, B., Chattranukulchai, P., Santanakorn, Y., Hutayanon, P., Khunrong, P., Bunyapipat, T., Jai-Aue, S., Kaewsuwanna, P., Bamungpong, P., Gunaparn, S., Hongsuppinyo, S., Inphontan, R., Khattaroek, R., Khunkong, K., Kitmapawanont, U., Kongsin, C., Naratreekoon, B., Ninwaranon, S., Phangyota, J., Phrommintikul, A., Phunpinyosak, P., Pongmorakot, K., Poomiphol, S., Pornnimitthum, N., Pumprueg, S., Ratchasikaew, S., Sanit, K., Sawanyawisuth, K., Silaruks, B., Sirichai, R., Sriwichian, A., Suebjaksing, W., Sukklad, P., Suttana, T., Tangsirira, A., Thangpet, O., Tiyanon, W., Vorasettakarnkij, Y., Wisaratapong, T., Wongtheptien, W., Wutthimanop, A., Yawila, S., Oto, A., Altun, A., Ozdogru, I., Ozdemir, K., Yilmaz, O., Aydinlar, A., Yilmaz, M. B., Yeter, E., Ongen, Z., Cayli, M., Pekdemir, H., Ozdemir, M., Sucu, M., Sayin, T., Demir, M., Yorgun, H., Ersanli, M., Okuyan, E., Aras, D., Abdelrahman, H., Aktas, O., Alpay, D., Aras, F., Bireciklioglu, M. F., Budeyri, S., Buyukpapuc, M., Caliskan, S., Esen, M., Felekoglu, M. A., Genc, D., Ikitimur, B., Karaayvaz, E. B., Kılıç Karataş, S., Okutucu, S., Ozcelik, E., Quisi, A., Sag, H., Sahiner, L., Sayin, B. Y., Seker, T., Uzun Alkan, D., Yildirim, E., Yildirim, R., Yilmaz, F., Yuksekdag, V., Luciardi, H. L., Vensentini, N., Ingaramo, A. C., Sambadaro, G. A., Fernandez Caputi, V., Berman, S. G., Dragotto, P., Kleiban, A. J., Centurion, N., Giacomi, G., Ahuad Guerrero, R. A., Conde, D., Zapata, G., Di Paola, L. A., Ramos, J. L., Dran, R. D., Egido, J., Fernandez, A. A., Fosco, M. J., Sassone, S., Sinisi, V. A., Cartasegna, L. R., Berli, M. A., Gomez Vilamajo, O. A., Ferroni, F., Alaguibe, E. D., Alvarez D'Amelio, A., Arabetti, C., Arias, L., Belardi, J. A., Bergesio, L., Berli, F., Berli, M., Borchowiec, S., Buzzetti, C., Cabrini, R., Campisi, V., Cappi, A. L., Carrizo, R., Colombo Berra, F., Costabel, J. P., Costamagna, O. J. A., Damonte, A. A., De Urquiza, I. N., Diez, F., Edén, M. F., Fanuele, M., Fernandez Voena, F., Foa Torres, M., Funosas, C., Giacomi, M. P., Gimenez, C. H., Gurfinkel, E. P., de L. M. Had, M., Hansen, V., Hrabar, A. D., Ingratta, M., Lopez, A., Maehara, G., Maffei, L., Martinelli, A., Martinelli, C., Matkovich, J., Mautner, B., Meirino, A., Munguia, R., Navarro, A., Novas, V., Perez Prados, G., Pontoriero, J., Potito, R. N., Ricotti, C., Rodriguez, M. A., Rolandi, F., Said Palladino, M. E., Salinger, M., Sanziani, L. S., Schygiel, P. O., Sossich, A., Tinto, J. F., Tonelli, L., Tufare, A. L., Vallejo, M., Yunis, M. E., Zillo, M., Zurbrigk, F. J., Barretto, A. C. P., Sobral Filho, D. C., Jaber, J., Armaganijan, D., Faria Neto, J., Steffens, A., Kunz Sebba Barroso de Souza, W., de Souza Neto, J. D., Ribeiro, J. M., Silveira Teixeira, M., Ferreira Rossi, P. R., Pires, L., Moreira, D., Moura Jorge, J. C., Menezes Lorga Filho, A., Bodanese, L. C., Westerlund Montera, M., Del Carlo, C. H., Da Rocha Rodrigues, T., Alves da Costa, F. A., Lopes, A., Lopes, R., Araújo, G. R., Fernandes Manenti, E. R., Kerr Saraiva, J. F., Ferreira Braga, J. C., Negri, A., Souto, L., Moncada, C., Bertolim Precoma, D., Roquette, F., Reis, G., Ramos Filho, R. A., Lanna Figueiredo, E., Vieira Botelho, R., Munhoz da Fontoura Tavares, C., Costantini Frack, C. R., Abdalla Saad, J., Finimundi, H. C., Pisani, C., Chemello, D., Pereira Martins, M., Broilo França, C. C., Alban, F., Aranha Rosito, G. B., de Moura Xavier Moraes Junior, J. B., Tumelero, R. T., Nigro Maia, L., Simões de Almeida, R., do Carmo Borges, N. C., Gomes Ferreira, L. G., Agliardi, P., Alves de Oliveira Gomes, J., Araujo, V., Arruda Nakazone, M., Barbosa, T., Barroso, S., Belisario Falchetto, E., Bellotti Lopes, H., Benez Teixeira Lemos, M. A., Biazus, G., Borges Queiroz, L., Camazzola, F. E., Caporale, M., Cardoso Boscato, S., Chieza, F., Chokr, M. O., Clemente Mingireanov, R., Codonho Góes, N., Correa, C., Costa, M., Costantini Ortiz, C., da Silva, L. S., da Silva Paulitsch, F., da Silveira, J. A., Daros, E., de Araújo, G. R., Del Monaco, M. I., Dias, C., Dias, M. A., Drummond Wainstein, A. P., Ely Pizzato, P., Esteves, D. C., Fabri, P., Félix Lorenzato Fonseca, T., Fernandes, E., Fonseca, C., Frack Costantini, C. R., Franchin Ferraz, R., Freire, F., Gottardo, P., Guanaes, D., Guizzardi, S., Hettwer Magedanz, E., Igansi, F., Jannuzzi, F., Junior, G., Komar, D., Lino, E. G., Lopes, D., Lourenço da Silva Júnior, O., Lustosa, E., Macagnan, A. P., Marinho, M. C., Mazzoni, M., Melo, G., Mortari, L., Mouco, O. M. C. C., Nanzer Vital, C., Ormundo, C., Oss Emmer, S., Palmegiani, E., Pavani, R., Pereira, L., Pereira, V. L., Perreira, R., Poletti, S., Quaia Fortunato, S. C., Queirantes, C., Ramos Pereira, N., Rech, R. L., Ribeiro, S., Rodrigues, A., Roesch, H., Ruaro Reichert, T., Santos, D., Santos, I., Santos, M., Seroqui, M. V., Silva, S., Soares, L., Spolaor, L., Stoll, C., Toazza Duda, N., Trama, L., Unterkircher, B., Valois, M. V., Vargas, T., Viana, T., Vicente, C., Vidal Armaganijan, L., Vieira Homem, R., Vieira Torres, L. G., Vila Boas, L., Villaça Guimarães Filho, F., Corbalan, R., Eggers, G., Bugueño Gutiérrez, C., Arriagada, G., Potthoff Cardenas, S., Stockins Fernandez, B. A. J., Conejeros, C., Houzvic, C., Marin Cuevas, P., Montecinos, H., Forero, A., Lanas, F., Larico Gómez, M., Charme Vilches, G., Rey, C., Astudillo, C., Aguilar, J., Campisto, Y., Lara, C., Molina, E., Munoz Oyarzon, J., Olguin, V., Vergara, M., Villan, C., Sánchez Díaz, C. J., Illescas Diaz, J., Leal Cantú, R., Ramos Zavala, M. G., Cabrera Jardines, R., Espinola Zavaleta, N., Villarreal Umaña, S., López Rosas, E., Llamas Esperón, G., Pozas, G., Cardona Muñoz, E., Matadamas Hernández, N., Leyva Rendón, A., García Hernández, N., de los Ríos Ibarra, M., Virgen Carrillo, L., López Villezca, D., Hernández Herrera, C., López Prieto, J. J., Gaona Rodríguez, R., Villeda Espinosa, E., Flores Martínez, D., Velasco Barcena, J., Yong, R., Rodríguez Briones, I., Leiva Pons, J. L., Álvarez López, H., Olvera Ruiz, R., Díaz de la Vega, C., Cantú Brito, C., Chuquiure Valenzuela, E., Reyes-Sanchez, R., Bazzoni Ruiz, A., Nandayapa Flores, O., Benavides Gonzalez, M., Arriaga Nava, R., Morales Cerda, J. D., Fierro Fierro, O., Fajardo Campos, P., Alfaro, T. A. A., Altamirano Bellorin, S., Avena, R., Chavarria, M., Espinosa, I., Flores Silva, F., Garcia Nava, R. H., Godoy, K., Gonzalez Felix, E. J., Gonzalez Garcia, C. L., Gonzalez Salas, L. G., Guajardo, P., Hernandez Gonzalez, S., Izquierdo, T., Mancilla Ortiz, M. C., Martinez Vasquez, D., Mendoza, N., Morales, J., Nikitina, N., Ochoa Aybar, S., Ortiz, A., Padilla Macias, P., Perez, F., Perez Sanchez, J. A., Piña Toledano, S., Ramos Gonzalez, M., Rivera Ramos, C., Roa Castro, V., Romero Cardona, G., Ruiz Cornejo, M., Salinas, A., Santana, G., Sida Perez, P., Tovar Castaneda, A. C., Trujillo Cortes, R., Brodmann, M., Lenz, K., Drexel, H., Foechterle, J., Hagn, C., Podczeck-Schweighofer, A., Huber, K., Winkler, M., Schneeweiß, B., Gegenhuber, A., Lang, W., Eichinger-Hasenauer, S., Kaserer, P., Sykora, J., Rasch, H., Pichler, M., Schaflinger, E., Strohmer, B., Breier, R., Ebner, K. -M., Eischer, L., Freihoff, F., Lischka-Lindner, A., Mark, T., Mirtl, A., Said, A., Stöcklöcker, C., Vogel, B., Vonbank, A., Wöhrer, C., Zanolin, D., Cools, F., Paparella, G., Vandergoten, P., Parqué, J. -L., Capiau, L., Vervoort, G., Wollaert, B., Desfontaines, P., Mairesse, G., Boussy, T., Godart, P., De Wolf, A., Voet, J., Heyse, A., Hollanders, G., Anné, W., Vercammen, J., Purnode, P., Blankoff, I., Faes, D., Balthazar, Y., Beutels, M., Maréchal, P., Verstraete, S., Xhaet, O., Striekwold, H., Thoeng, J., Hermans, K., Alzand, B., Ascoop, A. -K., Banaeian, F., Barbuto, A. -M., Billiaux, A. C., Blockmans, M., Bouvy, C., Brike, C., Capiau, H., Casier, T., Conde Y Bolado, A., De Cleen, D., De Coninck, M., de Vos, M., de Weerdt, N., Delforge, M., Delvigne, M., Denie, D., Derycker, K., Deweerd, E., Dormal, F., Drieghe, S., Everaert, M., Eykerman, T., Feys, E., Ghekiere, M., Gits, F., Hellemans, S., Helvasto, L., Jacobs, C., Lips, S., Mestdagh, I., Nimmegeers, J., Piamonte, V., Pollet, P., Postolache, A., Raepers, M., Raymenants, E., Richa, J., Rombouts, H., Salembier, J., Scheurwegs, C., Semeraro, O., Simons, N., Smessaert, C., Smolders, W., Stockman, I., Tahon, S., Thyssen, V., Tincani, G., Van Durme, F., Van Lier, D., Vandekerckhove, H., Vandekerckhove, Y., Vandenbroeck, D., Vandorpe, A., Vanhalst, E., Vanhauwaert, B., Vantomme, C., Vergauwen, L., Verloove, H., Vydt, T., Weyn, T., Jansky, P., Reichert, P., Spacek, R., Machova, V., Zidkova, E., Ludka, O., Olsr, J., Kotik, L., Plocova, K., Racz, B., Ferkl, R., Hubac, J., Kotik, I., Monhart, Z., Burianova, H., Jerabek, O., Pisova, J., Petrova, I., Dedek, V., Honkova, M., Podrazil, P., Spinar, J., Vitovec, J., Novak, M., Lastuvka, J., Durdil, V., Antonova, P., Bockova, L., Bultas, J., Chlumsky, J., Dastychova, L., Drasnar, T., Honek, J., Horejsi, M., Hubacova, V., Janska, L., Kopeckova, I., Kratochvilova, R., Krcova, E., Labrova, R., Lindourkova, A., Lipoldova, J., Lubanda, H., Ludkova, A., Mahdalikova, L., Majerníkova, M., Michalik, D., Potuznik, P., Prochazkova, E., Sulc, A., Sveceny, J., Valtova, M., Zidek, M., Zika, J., Nielsen, J., Nielsen, H., Husted, S., Hintze, U., Rasmussen, S., Bremmelgaard, A., Markenvard, J., Boerger, J., Solgaard, J., Simonsen, P., Loekkegaard, T., Bruun, M., Mertz, J., Domínguez, H., Skagen, K., Egstrup, K., Ibsen, H., Raymond, I., Bang-Hansen, T., Ellervik, C., Eriksen, E., Jensen, L., Jensen, M., Leth, M., Nygaard, A., Park, J., Schou, M., Therkelsen, A., Tilma, J., Vesterager, K., Raatikainen, P., Airaksinen, J., Arola, O., Koistinen, J., Nappila, H., Peltomäki, K., Rasanen, V., Vasankari, T., Le Heuzey, J. -Y., Galinier, M., Gottwalles, Y., Paganelli, F., Loiselet, P., Muller, J. -J., Koujan, M. B., Marquand, A., Destrac, S., Piot, O., Delarche, N., Cebron, J. -P., Boveda, S., Guenoun, M., Guedj-Meynier, D., Galley, D., Ohayon, J., Assouline, S., Zuber, M., Amarenco, P., Ellie, E., Kadouch, J., Fournier, P. -Y., Huberman, J. -P., Lemaire, M., Rodier, G., Milandre, L., Vandamme, X., Sibon, I., Neau, J. -P., Mahagne, M. H., Mielot, A., Bonnefoy, M., Churet, J. -B., Navarre, V., Sellem, F., Monniot, G., Boyes, J. -P., Doucet, B., Martelet, M., Obadia, D., Crousillat, B., Mouallem, J., Bearez, E., Nazeyrollas, P., Brugnaux, J. P., Fedorowsky, A., Casassus, F., Berneau, J. -B., Chemin, F., Falvo, N., Perron, J. -M., Poulard, J. -E., Barreau, A., Beltra, C., Corrihons, E., Decarsin, N., Dubois, B., Ducasse, E., Giry, X., Kemmel, A., Ledure, S., Lemaire, N., Robin, F., Rosolin, N., Sanchez, D., Suissa, A., Darius, H., Königer, G., Purr, J., Gerbaulet, U., Kellner, B. -T., Kopf, A., Schäfer, T., Zauzig, H., Riegel, P., Hohensee, H., Eißfeller, E., Eder, W., Rehling, G., Glatzel, D., Zutz, S., Heinz, G. -U., Menke, H., Pustelnik, A., Sandow, P., Ludwig, N., Wiswedel, H., Wildenauer, W., Axthelm, C., Schwarz, T., Babyesiza, A., Stuchlik, G., Zimny, H. -H., Kropp, M., Kahl, F., Caspar, A., Omankowsky, S., Läßig, T., Hartmann, H. -J., Lehmann, G., Bindig, H. -W., Hergdt, G., Reimer, D., Hauk, J., Dorsch, W., Dshabrailov, J., Michel, H., Rapp, K. -A., Vormann, R., Mayer, P., Horstmeier, U., Eissing, V., Hey, H., Leuchtgens, H., Lilienweiß, V., Kolitsch, K., Schubert, C., Lauer, H., Buchner, T., Brauer, G., Kamin, S., Müller, K., Abdel-Qader, M., Baumbach, S., Ebert, H. -H., Schwencke, C., Schellong, S., Bernhardt, P., Karolyi, L., Sievers, B., Haverkamp, W., Salbach, P., Röhnisch, J. -U., Schoen, S., Erdle, W., Mueller, T., Mueller, H., Mitrovic, V., Babjakova, Z., Bergner, K., Boehme, S., Bonin, K., Buckert, D., Busch, F., Dichristin, U., Diez, S., Fleck, A., Flint, K., Floegel, H., Fritz, C., Frommhold, R., Gehre, J., Geyer, J., Grytzmann, A., Hahn, M., Helgert, K., Hubert, K., Kirchner-Volker, K., Klein, V., Kroll, D., Krueger, A., Lehmann, R., Mann, L., Maselli, A., Menken, G., Mikes, K., Mortan, H., Nasser, N., Nicolaus, D., Plauskat, A., Pomper, L., Quietzsch, A., Ravenhorst, C., Reichelt, C., Reimer, C., Schaefer, B., Scharrer, S., Schirmer, K., Schmidt, K., Schoene, R., Schulze, J., Schuppe, M., Simon, S., Sommer, S., Spranger, K., Talkenberger, A., Tauber, K., Tetlak, A., Toennishoff, T., Voelkel-Babyesiza, R., Voigts, B., Weiser, U., Wesendorf, S., Wildenauer, S., Wolf, T., Wurziger, J., Zak, J., Zauzig, H. -D., Ziefle, S., Zincke, S., Keltai, M., Vangel, S., Szalai, G., Merkely, B., Kancz, S., Boda, Z., Nagy, A., Laszlo, Z., Matoltsy, A., Gaszner, B., Polgar, P., Habon, T., Noori, E., Juhasz, G., Kanakaridisz, N., Szentpeteri, I., Juhasz, F., Vertes, A., Papp, A., May, Z., Ferenczi, J., Egyutt, M., Kis, E., Engelthaler, G., Szantai, G., Fulop, E., Gombos, P., Gulyas, D., Jen, P., Kiralyhazine Gyorke, E., Kovacs, M., Kovacsne Levang, S., Marianna, S., Radics, Z., Sydó, N., Szalo, R., Szilagyi, A., Sztanyik, F., Vandrus, B., Agnelli, G., Ambrosio, G., Tiraferri, E., Santoro, R., Testa, S., Di Minno, G., Moia, M., Caimi, T. M., Martini, G., Tessitori, M., Cappelli, R., Poli, D., Quintavalla, R., Melone, F., Cosmi, F., Pizzini, A., Piseddu, G., Fanelli, R., Latella, C., Santi, R., Pancaldi, L., De Cristofaro, R., Palareti, G., De Blasio, A., Salerno Uriarte, J., Minetti, F., Pogliani, E. M., Lonati, L. M., Accogli, M., Ciampani, N., Malengo, S., Feola, M., Raisaro, A., Fattore, L., Grilli, P., Germini, F., Settimi, M., Alunni, M., Duranti, G., Tedeschi, L., Baglioni, G., Avanzino, G., Berardi, M., Pannacci, V., Giombolini, A., Nicoli, S., Scarponi, T., Allasia, B., Ricciarini, P., Nasorri, R., Argena, A., Bossolasco, P., Ronchini, P., Filippi, A., Tradati, F., Bulla, C., Donzelli, L., Foppa, L., Bottarelli, M. L., Tomasello, A., Mauric, A., Femiano, C., Reggio, R., Lillo, F., Mariani, A., Forcignanò, F., Volpe, M., D'Avino, M., Bongiorni, M. G., Severi, S., Capucci, A., Lodigiani, C., Salomone, E., Serviddio, G., Tondo, C., Golino, P., Mazzone, C., Iacopino, S., Pengo, V., Galvani, M., Moretti, L., Ambrosino, P., Banfi, E., Biagioli, V., Bianchi, A., Boggian, G., Breschi, M., Brusorio, S., Calcagnoli, F., Campagna, G., Carpenedo, M., Ciabatta, C., Ciliberti, G., Cimmino, G., D'Arienzo, C., Di Gennaro, L., Fedele, M., Ferrini, P. M., Granzow, K., Guazzaloca, G., Guerra, F., Lo Buglio, A., Longo, S., Macellari, F., Mesolella, E., Mollica Poeta, E., Occhilupo, P., Oriana, V., Rangel, G., Salomone, L., Scaccianoce, A., Scarone, C., Segreti, L., Sottilota, G., Villani, R., Zecca, C., ten Cate, H., Ruiter, J. H., Klomps, H., Bongaerts, M., Pieterse, M. G. C., Guldener, C., Herrman, J. -P., Lochorn, G., Lucassen, A., Adriaansen, H., The, S. H. K., Nierop, P. R., Hoogslag, P. A. M., Hermans, W., Groenemeijer, B. E., Terpstra, W., Buiks, C., Boersma, L. V. A., Boersma-Slootweg, M., Bosman, F., Bosschaert, M., Bruin, S., Danse, I., De Graaf, J., de Graauw, J., Debordes, M., Dols, S., Geerlings, F., Gorrebeeck, K., Jerzewski, A., Jetten, W., Kelderman, M., Kloosterman, T., Koomen, E. M., Krikken, J., Melman, P., Mulder, R., Pronk, A., Stallinga-de Vos, A., te Kaat, J., Tonino, P., Uppelschoten, B., van de Loo, R., van der Kley, T., van Leeuwen, G., van Putten, J. J., Westerman, L., Atar, D., Berge, E., Sirnes, P. A., Gjertsen, E., Hole, T., Erga, K., Hallaråker, A., Skjelvan, G., Østrem, A., Ghezai, B., Svilaas, A., Christersson, P., Øien, T., Høegh Henrichsen, S., Berg-Johansen, J., Otterstad, J. E., Antonsen, H., Ausen, K., Claussen, H., Dominguez, I., Jekthammer, A., Lensebraaten, A. B., Nilsen, V., O'Donovan, M., Ringdalen, K., Strand, S., Stepinska, J., Korzeniak, R., Gieroba, A., Biedrzycka, M., Ogorek, Marcin, Wozakowska-Kaplon, B., Loboz-Grudzien, K., Kosior, J., Supinski, W., Kuzniar, J., Zaluska, R., Hiczkiewicz, J., Swiatkowska-Byczynska, L., Kucharski, L., Gruchala, M., Minc, P., Olszewski, M., Kania, G., Krzciuk, M., Lajkowski, Z., Ostrowska-Pomian, B., Lewczuk, J., Zinka, E., Karczmarczyk, A., Chmielnicka-Pruszczynska, M., Trusz-Gluza, M., Opolski, G., Bronisz, M., Ogorek, Michal, Glanowska, G., Ruszkowski, P., Jaworska, K., Sciborski, R., Okopien, B., Kukla, P., Wozniak-Skowerska, I., Galbas, K., Cymerman, K., Jurowiecki, J., Miekus, P., Myszka, W., Mazur, S., Lysek, R., Baszak, J., Rusicka-Piekarz, T., Raczak, G., Domanska, E., Nessler, J., Lesnik, J., Ambicka, M., Andrzejewski, D., Araminowicz, J., Barszcz, A., Bartkowiak, R., Bartnik, J., Basiak, M., Bekieszczuk, E., Bernat, L., Biedrzycki, L., Biernacka, A., Blaszczyk, D., Broton, E., Brzozowski, W., Brzustowska, M., Bzymek, R., Chmielowski, A., Chojnowski, P., Cichomski, R., Cieslak, K., Cieszynska, A., Curyllo, B., Czamara, M., Danilowicz-Szymanowicz, L., Dolecka, B., Drelich, L., Dudzik-Richter, B., Dybala, T., Dziuba, M., Faron, W., Figura-Chmielewska, M., Frankiewicz, A., Gadzinski, W., Gasior, E., Gosciniecka, B., Gutknecht, P., Guziewicz, M., Jackun-Podlesna, A., Jaguszewska, G., Jankielewicz, J., Jaremczuk-Kaczmarczyk, A., Jargiello-Baszak, M., Jarzebowski, A., Jaskulska-Niedziela, E., Jaworska-Drozdowska, M., Kabat, J., Kaczmarzyk-Radka, A., Kalin, K., Kaliszczak, R., Kiliszek, M., Klata, M., Kluczewski, M., Kobielusz-Gembala, I., Kochanska, E., Kociolek, D., Kolodzinska, A., Komlo, A., Konopka, A., Korczowska, E., Kowal, E., Kowalczyk, H. K., Kremis, E., Kruczyk, D., Krzesiak-Lodyga, A., Krzyzanowski, M., Kurdzielewicz, W., Kustrzycka-Kratochwil, D., Lesniewska-Krynska, D., Leszczynski, J., Lewicka, E., Lichota, E., Lip, K., Loboz-Rudnicka, M., Luka, J., Lysek-Jozefowicz, A., Machnikowska, M., Majewska, K., Mariankowski, R., Markiewicz, A., Mazur, M., Metzgier-Gumiela, A., Miedlar, E., Mielcarek, M., Neubauer-Geryk, J., Niedek, J., Niemirycz-Makurat, A., Nowak, A., Nowak, S., Opielowska-Nowak, B., Ozgowicz, M., Pawelska-Buczen, A., Pawlik-Rak, E., Piotrowicz, R., Ptaszynski, P., Raczynska, A., Rogowski, W., Romanek, J., Romaszkiewicz, R., Rostoff, P., Roszczyk, N., Rozewska-Furmanek, D., Rychta, J., Rzyczkowska, B., Sidor, A., Skalska, J., Smichura, M., Splawski, M., Staneta, P., Staniszewska, E., Starak-Marciniak, J., Stopyra-Poczatek, M., Sukiennik-Kujawa, M., Szafranski, J., Szalecki, P., Szczepanska, A., Szkrobka, W., Szuchnik, E., Szulowska, A., Szumczyk-Muszytowska, G., Szwoch, M., Traczyk, T., Troszczynska, M., Trzcinski, G., Tybura, S., Walasik, P., Wegrzynowska, M., Wesolowska, K., Wieczorek, W., Wierzbicka, A., Wilczewski, P., Wilgat-Szecowka, M., Wojewoda, P., Wojnowski, L., Wrobel, M., Zakutynska-Kowalczyk, K., Zyczynska-Szmon, M., Panchenko, E., Eltishcheva, V., Libis, R., Tereshchenko, S., Popov, S., Kamalov, G., Belenky, D., Zateyshchikova, A., Kropacheva, E., Kolesnikova, A., Nikolaev, K., Egorova, L., Khokhlov, A., Yakupov, E., Poltavskaya, M., Zateyshchikov, D., Drapkina, O., Vishnevsky, A., Barbarash, O., Miller, O., Aleksandrova, E., Chizhov, P., Sergeev, M., Shutemova, E., Mazur, E., Zrazhevskiy, K., Novikova, T., Kostenko, V., Moiseeva, Y., Polkanova, E., Sobolev, K., Rossovskaya, M., Zubeeva, G., Shapovalova, Y., Nagibovich, O., Edin, A., Agakhanyan, A., Batalov, R., Belenkova, Y., Bitakova, F., Chugunnaya, S., Dumikyan, A., Erofeeva, S., Gorbunova, E., Gorshkova, T., Gubanov, A., Gurmach, M., Ivanova, Y., Kolesova, T., Konyushenko, D., Korneeva, O., Kropova, O., Kuchuk, P., Kungurtseva, O., Kupriyanova, T., Kurylo, B., Kuvanova, M., Lebedeva, O., Lileeva, E., Machilskaya, O., Medvedeva, T., Monako, G., Motylev, I., Nagibovich, G., Novikova, E., Orlov, Y., Osmolovskaya, Y., Ovsannikova, A., Platonov, D., Rachkova, S., Sinitsina, O., Speshilova, S., Suslova, O., Ushakov, A., Volodicheva, O., Zemlianskaia, O., Zhirov, I., Zhuravleva, E., Zotova, I., Viñolas, X., Alvarez Garcia, P., López Fernández, M. F., Tercedor, L., Tranche Iparraguirre, S., Torán Monserrat, P., Márquez Contreras, E., Isart Rafecas, J., Motero Carrasco, J., García Pavía, P., Gómez Pajuelo, C., Moro Serrano, C., Iglesias Alonso, L. F., Grande Ruiz, A., Mercé Klein, J., Gonzalez Juanatey, J. R., Barón Esquivias, G., Monte Collado, I., Palacín Piquero, H., Brotons Cuixart, C., Rodríguez Morató, M., Bayo I Llibre, J., Corros Vicente, C., Vida Gutierrez, M., Epelde Gonzalo, F., Almeida Fernández, C. A., Del Val Plana, N., Escrivá Montserrat, E., Montero Alía, J. J., Barreda González, M., Moleiro Oliva, M. A., Iglesias Sanmartín, J., Jiménez González, M., Rodriguez Álvarez, M., Herreros Melenchon, J., Ripoll Vera, T., Ridocci Soriano, F., Garcia Riesco, L., Marco Macian, M. D., Quiles Granado, J., Jimenez Navarro, M., Cosin Sales, J., Vaquer Perez, J. V., Vazquez Caamano, M., Arcocha Torres, M. F., Marcos Gomez, G., Iñiguez Romo, A., Prieto Diaz, M. A., Alonso, Carmela, Alonso, Concepcion, Alvarez, D., Alvarez, M., Amaro, M., Andere, N., Aracil Villar, J., Armitano Ochoa, R., Austria, A., Barbeira, S., Barraquer Feu, E., Bartes, A., Becerra Munoz, V., Bermudez Jimenez, F. J., Branjovich Tijuan, A., Cabeza Ramirez, J., Cabrera Ramos, M., Calvo Martinez, E., Campo Moreno, M., Cancho Corchado, G., Casanova Gil, M., Castillo Orive, M., Castro Fernandez, D., Cebollada del Misterio, M., Codinachs Alsina, R., Cortada Cabrera, A., Costa Pinto Prego de Faria, J., Costas, S., Cotilla Marco, M. I., Dachs, M., Diaz Lopez, C. M., Domenech Borras, A., Elorriaga Madariaga, A., Espallargas, A., Fernandez, M., Fernandez Escobar, E., Fernandez Mas, E., Ferrer, A., Fosch, J., Garcia Bermudez, M., Garcia Millan, V., Gavira Saenz, M., Gines Garcia, C., Gomez, C., Gomez Perez, Y., Gonzales Segovia, A., Gonzalez, P., Grigorian, L., Guerrero Molina, A., del C. Gutierrez del Val, M., Herrero Maeso, B., Hevia Rodriguez, E., Iglesias Garcia, A., Jimenez Fernandez, M. J., Jimeno Besa, B., Juan Salvadores, P., Lage Bouzamayor, M. B., Lasuncion, I., Lezcano Gort, L. E., Llobet Molina, M., Lopez, M., Manzanal Rey, A., Mara Guerra, J., Marcus, S., Martin Vila, A., Martinez Mena, M., Mazon, P., Mendez Zurita, F., Millán, G., Molina, M., Montero Alia, P., Montes, D., Moure Gonzalez, M., Munoz Munoz, R. B., Negrete Palma, A., Orellana Figueroa, H. N., Ortega, V. M., Ortiz Cortes, C., Otero Tomera, D., Palomo Merchan, N., Pareja Ibar, I., Pena Garcia, E., Pereda Armayor, M., Perez Carasa, M., Prieto, I., Quintern, V., Renom, R., Rincon Diaz, L. M., Rios, V., Riquelme Sola, L., Rivera, R., Robiro Robiro, X., Roca, M., Roca Saumell, C., Rodrigo, C., Rodriguez, E., Rodriguez Garcia, M., Saez Jimenez, S., Sanchez Calderon, P., Sanchez Mendez, L., Sanchez Parra, S., Santolaya, C., Senan Sanz, M. R., Seoane Blanco, A., Serralvo, E., Sierra, N., Simon Valero, C., Sorribes Lopez, J., Teixido Fontanillas, M., Terns Riera, M., Tobajas, G., Torres, C., Torres Marques, J., Ubeda Pastor, M., Rosenqvist, M., Wirdby, A., Linden, J., Henriksson, K., Elmersson, M., Egilsson, A., Börjesson, U., Svärd, G., Liu, B., Lindh, A., Olsson, L. -B., Gustavsson, M., Andersson, Lar, Andersson, Lisbeth, Benson, L., Bothin, C., Hajimirsadeghi, A., Kadir, K., Ericsson, M., Ohlsson, A., Lindvall, H., Svensson, P., Thorne, K., Handel, H., Platonov, P., Eriksson, B., Timberg, I., Romberg, K., Crisby, M., Karlsson, J. -E., Jensen, S. A., Andersson, A., Malmqvist, L., Martinsson, B., Bernsten, F., Engdahl, J., Thulin, J., Hot-Bjelac, A., Stalby, P., Aaröe, H., Ahbeck, E., Ahlmark, H., Al-Khalili, F., Bonkowski, G., Dzeletovic, S., Ekstrand, A. -B., Eriksson, G. -B., Floren, K., Grässjö, C., Hahn, S., Jaensson, P., Jansson, B., Jansson, J. -H., Kangert, R. -M., Koch, A., Kusiak, D., Lettenström, A., Lindberg, A., Lindholm, C. -J., Mannermyr, A., Mansson, K., Millborg, M., Nilsson, C., Ohlin, A. -M., Olofsson, A., Osberg, A., Pedersen, A., Risbecker, K., Rosenberg, K., Samuelsson, J., Shayesteh, M., Skoglund, K., Stjernberg, M., Thorsen, C., Steffel, J., Beer, J. H., Debrunner, J., Amstutz, D., Bruegger, J., Elise, G., Grau, A., Guinand, A., Henriette, I., Saga, E., Winnik, S., Parkhomenko, A., Rudyk, I., Tseluyko, V., Karpenko, O., Zhurba, S., Kraiz, I., Kupnovytska, I., Serediuk, N., Mostovoy, Y., Ushakov, O., Koval, O., Kovalskyi, I., Svyshchenko, Y., Sychov, O., Stanislavchuk, M., Kraydashenko, O., Yagensky, A., Tykhonova, S., Fushtey, I., Belegai, R., Berko, G., Burdeuna, L., Chabanna, O., Daniuk, I., Ivanov, A., Kamenska, E., Kaplan, P., Khyzhnyak, O., Kizim, S., Matova, O., Medentseva, O., Mochonyi, V., Mospan, M., Nemtsova, V., Ovdiienko, T., Palamarchuk, O., Pavelko, M., Petrovskyy, R., Plevak, D., Proshak, O., Pyvovar, S., Rasputina, L., Romanenko, O., Romanova, O., Sapatyi, A., Shumakov, O., Stets, R., Todoriuk, L., Varenov, V., Fitzmaurice, D., Chauhan, N., Goodwin, D., Saunders, P., Evans, R., Leese, J., Jhittay, P. S., Ross, A., Kainth, M. S., Pickavance, G., Mcdonnell, J., Williams, A., Gooding, T., Wagner, H., Suryani, S., Singal, A., Sircar, S., Bilas, R., Hutchinson, P., Wakeman, A., Stokes, M., Paul, N., Aziz, M., Ramesh, C., Wilson, P., Franklin, S., Fairhead, S., Thompson, J., St Joseph, V., Taylor, G., Tragen, D., Seamark, D., Paul, C., Richardson, M., Jefferies, A., Sharp, H., Jones, H., Giles, C., Page, M., Oginni, O., Aldegather, J., Wetherwell, S., Lumb, W., Evans, P., Scouller, F., Macey, N., Stipp, Y., West, R., Thurston, S., Wadeson, P., Matthews, J., Pandya, P., Gallagher, A., Railton, T., Sinha, B., Russell, D., Davies, J. A., Ainsworth, P., Jones, C. P., Weeks, P., Eden, J., Kernick, D., Murdoch, W., Lumley, L., Patel, R. P., Wong, S. W., Saigol, M., Ladha, K., Douglas, K., Cumberlidge, D. F., Bradshaw, C., Van Zon, G., Jones, K. P., Thomas, M. J., Watson, E., Sarai, B., Ahmad, N., Willcock, W., Cairns, J., Sathananthan, S., de Kare-Silver, N., Gilliland, A., Strieder, E., Howitt, A., Vishwanathan, B., Bird, N., Gray, D., Clark, M., Bisatt, J., Litchfield, J., Fisher, E., Fooks, T., Kelsall, A. R., Alborough, E., Wakeling, J., Parfitt, M., Milne, K., Rogers, S., Priyadharshan, R., Oliver, J. L., Davies, E., Abushal, S., Jacobs, M., Hutton, C., Walls, N. I., Thompson, R., Chigbo, C., Zaidi, S. M. A., Howard, M., Butter, K. C., Barrow, S., Little, H., Haq, I. U., Gibbons, L., Glencross, S., Mcleod, A. J., Poland, K., Mulholland, C., Warke, A., Conn, P., Burns, G., Smith, R. N., Lowe, S., Kamath, R., Dau, H. S., Webster, J., Hodgins, I., Vercoe, S., Roome, P. C., Pinnock, H., Patel, J. R. A., Ali, A., Hart, N., Davies, R., Stuart, E., Neden, C. A., Danielsen, M., Heath, R., Sharma, P., Galloway, S., Hawkins, C., Oliver, R., Aylward, M., Mannion, S., Braddick, M., Edwards, D., Rothwell, A. C., Sabir, A., Choudhary, F., Khalaque, S., Wilson, A., Peters, S., Coulson, W., Roberts, N., Heer, A., Coates, S., Ward, B., Jackson, D., Walton, S., Shepherd, D., Sterry, M., Wong, T., Boon, M., Bunney, R., Haria-Shah, R., Baron, R. T., Davies, S., Schatzberger, T., Hargreaves, N., Stephenson, T., Choi, H., Batson, R., Lucraft, L., Myhill, T., Estifano, S., Geatch, D., Wilkinson, J., Veale, R., Forshaw, K., Davies, T., Zaman, K., Vinson, P., Liley, C., Bandrapalli, M., Mcginty, P., Wastling, R., Mceleny, P., Beattie, A., Cooke, P., Wong, M., Gunasegaram, J., Pugsley, M., Ahmad, S., A'Court, C., Ayers, J., Bennett, J., Cartwright, S., Dobson, S., Dooldeniya, C., Flynn, A., Fox, R., Goram, J., Halpin, A., Hay, A., Jacobs, P., Jeffers, L., Lomax, L., Munro, I., Muvva, R., Nadaph, M., Powell, K., Randfield, S., Redpath, D., Reed, R., Rickenbach, M., Rogers, G., Saunders, P. B., Seamark, C., Shewring, J., Simmons, P., Simper, H., Stoddart, H., Sword, A., Thomas, N., Thomson, A., Gibbs, H., Blenkhorn, A., Singh, B., Van Gaal, W., Abhayaratna, W., Lehman, R., Roberts-Thomson, P., Kilian, J., Coulshed, D., Catanchin, A., Colquhoun, D., Kiat, H., Eccleston, D., French, J., Zimmett, L., Ayres, B., Phan, T., Blombery, P., Crimmins, D., O'Donnell, D., Choi, A., Astridge, P., Arstall, M., Jepson, N., Binnekamp, M., Lee, A., Rogers, J., Starmer, G., Carroll, P., Faunt, J., Aggarwala, A., Barry, L., Batta, C., Beveridge, R., Black, A., Bonner, M., Boys, J., Buckley, E., Campo, M., Carlton, L., Connelly, A., Conway, B., Cresp, D., Dimitri, H., Dixon, S., Dolman, M., Duroux, M., Eskandari, M., Eslick, R., Ferreira-Jardim, A., Fetahovic, T., Fitzpatrick, D., Geraghty, R., Gibbs, J., Grabek, T., Modi, M. H., Hayes, K., Hegde, M. P., Hesketh, L., Hoffmann, B., Jacobson, B., Johnson, K., Juergens, C., Kassam, I., Lawlor, V., Lehman, M., Lehman, S., Leung, D., Mackay, S., Mackenzie, M., Mccarthy, C., Mcintosh, C., Mckeon, L., Morrison, H., Mussap, C., Myers, J. -D., Nagalingam, V., Oldfield, G., O'May, V., Palmer, J., Parsons, L., Patching, K., Patching, T., Paul, V., Plotz, M., Preston, S., Rashad, H., Ratcliffe, M., Raynes, S., Rose, J., Sanders, L., Seremetkoska, M., Setio, H., Shone, S., Shrestha, P., Singh, C., Singleton, C., Stoyanov, N., Sutcliffe, S., Swaraj, K., Tarrant, J., Thompson, S., Tsay, I. M., Vorster, M., Waldman, A., Wallis, L., Wilford, E., Wong, K., Connolly, S. J., Spyropoulos, A., Eikelboom, J., Luton, R., Gupta, M., Pandey, A. S., Cheung, S., Leader, R., Beaudry, P., Ayala-Paredes, F., Berlingieri, J., Heath, J., Poirier, G., Du Preez, M., Nadeau, R., Dresser, G., Dhillon, R., Hruczkowski, T., Schweitzer, B., Coutu, B., Angaran, P., Macdonald, P., Vizel, S., Fikry, S., Parkash, R., Lavoie, A., Cha, J., Ramjattan, B., Bonet, J., Ahmad, K., Aro, L., Aves, T., Beaudry, K., Bergeron, C., Bigcanoe, J., Bignell, N., Breakwell, L., Burke, E., Carroll, L., Clarke, B., Cleveland, T., Daheb, S., Dehghani, P., Denis, I., Djaidani, Z., Dorian, P., Douglass, S., Dunnigan, J., Ewert, A., Farquhar, D., Fearon, A., Ferleyko, L., Fournier, D., Fox, B., Grenier, M. -C., Gulliver, W., Haveman, K., Hines, C., Hines, K., Jackson, A. M., Jean, C., Jethoo, G., Kahlon, R., Kelly, S., Kim, R., Korley, V., Kornder, J., Kwan, L., Largy, J., Lewis, C., Lewis, S., Mangat, I., Moor, R., Navratil, J., Neas, I., Otis, J., Otis, R., Pandey, M., Petrie, F., Pinter, A., Raines, M., Roberts, P., Robinson, M., Sas, G., Schulman, S., Snell, L., Spearson, S., Stevenson, J., Trahey, T., Wong, S., Wright, D., Ragy, H., Abd El-Aziz, A., Abou Seif, S. K., El Din, M. G., El Etriby, S., Elbahry, A., El-Etreby, A., Elkhadem, M., Katta, A., Khairy, T., Mowafy, A., Nawar, M., Ohanissian, A., Reda, A., Reda, M., Salem, H., Sami, N., Samir, S., Setiha, M., Sobhy, M., Soliman, A., Taha, N., Tawfik, M., Zaatout, E., Kettles, D., Bayat, J., Siebert, H., Horak, A., Kelfkens, Y., Garda, R., Pillay, T., Guerra, M., van Zyl, L., Theron, H., Murray, A., Louw, R., Greyling, D., Mntla, P., Ueckermann, V., Loghdey, R., Ismail, S., Ahmed, F., Engelbrecht, J., Ramdass, A., Maharajh, S., Oosthuysen, W., Angel, G., Bester, C., Booysen, M., Boshoff, C., Cannon, C., Cassimjee, S., Chami, C., Conway, G., Davids, A., de Meyer, L., Du Plessis, G., Ellis, T., Henley, L., Karsten, M., Loyd, E., Marks, J., Mavhusa, L., Mostert, M., Page, A., Rikhotso, L., Salie, M., Sasto, J., Shaik, F., Skein, A., Smith, L., Tarr, G., Tau, T., van Zyl, F., Al Mahmeed, W., Yousef, G., Agrawal, A., Nathani, M., Ibrahim, M., Esheiba, E. M., Singh, R., Naguib, A., Abu-Mahfouz, M., Al Omairi, M., Al Naeemi, A., Maruthanayagam, R., Bazargani, N., Wassef, A., Gupta, R., Khan, M., Subbaraman, B., Abdul, A., Al Mulla, A., El Bardisy, S., Haridas, P., Jadhav, S., Magdaluyo, K., Makdad, M., Maqsood, I., Mohamed, R., Sharma, N., Sharma, R., Thanzeel, M., Goldhaber, S. Z., Canosa, R., Rama, P., Blumberg, E., Garcia, J., Mullen, P., Wilson, V., Quick, A., Ferrick, K., Kutayli, W. M., Cox, M., Franco, M., Falkowski, S., Mendelson, R., Williams, M., Miller, S., Beach, S., Alfieri, A., Gutowski, T., Haque, I., Reddy, R., Ahmed, W., Delafontaine, P., Diercks, D., Theodoro, D., Remmel, K., Alberts, M., Ison, R., Noveck, H., Duffy, P., Pitta, S., Nishijima, D., Treasure, C., Asafu-Adjaye, N., Ball, K., Bartlett, M., Bentley, M., Bowers, S., Brown, A., Browne, A., Cameron-Watts, J., Canova, M., Cassidy, D., Cervellione, K., Congal, S., Depauw, J., Dickerson, A., Eley, M., Evans, L., Felpel, S., Ferdinand, K., Fielder, D., Gentry, P., Haideri, A., Hakimi, F., Harbour, T., Hartranft, E., Hawkins, B., Headlee, M., Henson, L., Herrick, C., Hicks, T., Jasinski, S., Jones, A., Jones, L., Jones, P., Karl, S., Keeling, M., Kerr, J., Knowles, P., Langdon, J., Lay, M., Lee, J. A., Lincoln, T., Malone, E., Merliss, A., Merritt, D., Minardo, J., Mooso, B., Orosco, C., Palumbo, V., Parker, M., Parrott, T., Paserchia, S., Pearl, G., Peterson, J., Pickelsimer, N., Purcell, T., Raynor, J., Raziano, S., Richard, C., Richardson, T., Robertson, C., Sage, A., Sanghera, T., Shaw, P., Shoemaker, J., Smith, K., Stephanie, B., Thatcher, A., Theobald, H., Thompson, N., Treasure, L., Tripti, T., Verdi, C., and Worthy, V.
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Registrie ,Male ,Time Factors ,Anticoagulant therapy, Arrhythmia, Atrial fibrillation, GARFIELD-AF ,030204 cardiovascular system & hematology ,Electrocardiography ,0302 clinical medicine ,Risk Factors ,Anticoagulant therapy ,Arrhythmia ,Atrial fibrillation ,GARFIELD-AF ,Aged ,Atrial Fibrillation ,Female ,Follow-Up Studies ,Humans ,Incidence ,India ,Prevalence ,Prognosis ,Prospective Studies ,Survival Rate ,Thromboembolism ,Registries ,Risk Assessment ,Medicine ,030212 general & internal medicine ,Prospective cohort study ,Incidence (epidemiology) ,cardiovascular system ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,Risk assessment ,Human ,medicine.medical_specialty ,Time Factor ,RD1-811 ,Prognosi ,Follow-Up Studie ,03 medical and health sciences ,Internal medicine ,Diseases of the circulatory (Cardiovascular) system ,cardiovascular diseases ,Risk factor ,Survival rate ,Fibrillation ,business.industry ,Risk Factor ,ta3121 ,medicine.disease ,Clinical trial ,Prospective Studie ,RC666-701 ,Surgery ,Clinical and Preventive Cardiology ,business - Abstract
Background: The Global Anticoagulant Registry in the FIELD–Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. Methods and results: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012–2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P
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- 2018
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43. Liver transaminase levels during pregnancy: a Japanese multicenter study
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Mamoru Yamashita, Takafumi Ushida, Kenji Imai, Tomomi Kotani, Noriyuki Nakamura, Hiroaki Kajiyama, Fumie Kinoshita, Yoshinori Moriyama, Tomoko Nakano-Kobayashi, and Shigeru Yoshida
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medicine.medical_specialty ,endocrine system diseases ,030204 cardiovascular system & hematology ,digestive system ,Gastroenterology ,Transaminase ,03 medical and health sciences ,0302 clinical medicine ,Japan ,Pregnancy ,Internal medicine ,medicine ,Humans ,Maternal Health Services ,Aspartate Aminotransferases ,030212 general & internal medicine ,Alanine aminotransferase ,Retrospective Studies ,business.industry ,Liver Diseases ,nutritional and metabolic diseases ,Obstetrics and Gynecology ,Alanine Transaminase ,medicine.disease ,digestive system diseases ,Liver ,Multicenter study ,Pediatrics, Perinatology and Child Health ,Female ,business ,hormones, hormone substitutes, and hormone antagonists - Abstract
There are conflicting reports on the effect of pregnancy on liver transaminase (aspartate aminotransferase [AST] and alanine aminotransferase [ALT]) levels. In this study, we sought to investigate the trajectories of AST and ALT levels during normal pregnancy and to compare them with AST and ALT levels of matched nonpregnant controls.Our multicenter retrospective study included 34,396 women who delivered at term at 12 primary maternity care units between January 2011 and December 2018 and 57,152 nonpregnant women younger than 45 years who received a medical checkup between 2016 and 2019. After matching at a ratio of 1:1 for adjustment of several factors (age, weight, and height), a total of 30,460 normal pregnant women and 30,460 nonpregnant women were selected for this study. We measured serum AST and ALT levels during each trimester and the postpartum period to compare with those of the nonpregnant women.The ALT level began to decrease in the first half of the third trimester and was lowest in the second half of third trimester and at postpartum day 1 (median [interquartile range]: 8 [6-11] U/L, 8 [6-10] U/L, respectively). The decline reversed and returned to the level of a nonpregnant state by postpartum days 2-7. The AST level remained unchanged regardless of pregnancy. The prevalence of abnormal liver transaminases (AST40 U/L and ALT40 U/L) was1% at third trimester; however, it increased to 3-5% on postpartum days 2-7.The ALT level was lower during pregnancy compared with nonpregnant women matched for several factors, whereas the AST level remained unchanged during pregnancy. Understanding the trajectories of AST and ALT levels during pregnancy may facilitate early recognition and diagnosis of impaired liver function, including liver disease and pregnancy complications that affect liver transaminases, such as pre-eclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome.
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- 2021
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44. Risk factors and outcomes of pediatric extracorporeal membrane oxygenation
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Tatsuo Iwasaki, Yosuke Kuroko, Shingo Kasahara, Hiroshi Taka, Yasuhiro Kotani, and Susumu Iwadou
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Heart Defects, Congenital ,Pulmonary and Respiratory Medicine ,Adolescent ,Heart disease ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,03 medical and health sciences ,Extracorporeal Membrane Oxygenation ,0302 clinical medicine ,Risk Factors ,Extracorporeal membrane oxygenation ,Humans ,Medicine ,In patient ,Favorable outcome ,Child ,Urine output ,Retrospective Studies ,business.industry ,Neurologic complication ,Medical record ,Infant, Newborn ,General Medicine ,medicine.disease ,Cardiopulmonary Resuscitation ,Treatment Outcome ,surgical procedures, operative ,030228 respiratory system ,Anesthesia ,Surgery ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background Congenital heart disease (CHD) is the most common neonatal and pediatric cardiac indication for extracorporeal membrane oxygenation (ECMO). Risk factors of survival and neurologic complication were different in many centers. We sought to evaluate survival and neurological outcome after ECMO in patients with CHD. Methods We retrospectively reviewed the medical records of 37 patients (Results The median ECMO duration was 160 (91–286) h. Twenty-nine patients (78%) were successfully weaned off ECMO. Overall survival to hospital discharge was 59%. Risk factors of mortality were as follows: ECMO duration >1 week and urine output Conclusions Longer ECMO duration and lower urine output were associated with increased mortality. Neurologic outcomes were not satisfactory when CPR was required for a longer period before ECMO establishment.
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- 2021
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45. Higher oxidized high-density lipoprotein to apolipoprotein A-I ratio is associated with high-risk coronary plaque characteristics determined by CT angiography
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Kazuhiro Osawa, Kentaro Ejiri, Takashi Miki, Hiroshi Ito, Kazuhiko Kotani, Hiroshi Morita, Toru Miyoshi, Kazuki Suruga, Kazufumi Nakamura, Keishi Ichikawa, and Hironobu Toda
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Male ,medicine.medical_specialty ,Apolipoprotein B ,Computed Tomography Angiography ,Coronary Artery Disease ,030204 cardiovascular system & hematology ,Coronary Angiography ,Coronary artery disease ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,High-density lipoprotein ,Risk Factors ,Internal medicine ,Coronary plaque ,medicine ,Humans ,030212 general & internal medicine ,Aged ,Apolipoprotein A-I ,biology ,medicine.diagnostic_test ,Cholesterol ,business.industry ,Angiography ,medicine.disease ,Plaque, Atherosclerotic ,Stenosis ,chemistry ,biology.protein ,Cardiology ,Female ,Lipoproteins, HDL ,Tomography, X-Ray Computed ,Cardiology and Cardiovascular Medicine ,business ,Follow-Up Studies ,Lipoprotein - Abstract
Oxidized high-density lipoprotein (oxHDL), unlike native HDL, is characterized by reduced cholesterol efflux capability and anti-inflammatory properties. The ratio of oxHDL to apolipoprotein A-I (oxHDL/apoAI) is a possible marker of dysfunctional HDL. The aim of this study was to evaluate the association between oxHDL/apoAI and coronary plaque characteristics that increase the likelihood of cardiovascular events as determined by coronary computed tomography (CT) angiography.A total of 297 patients (mean age; 67 years, men; 63%) who underwent coronary CT angiography for suspected stable coronary artery disease (CAD) were included. High-risk plaques (HRP) were defined by three characteristics: positive remodeling; low-density plaques; and spotty calcification. Significant stenosis was defined as a luminal narrowing of70%. Serum concentrations of oxHDL were measured using an enzyme-linked immunosorbent assay.Patients with higher oxHDL/ApoAI showed significantly greater prevalence of HRP (p = 0.03) and significant stenosis (p 0.01) compared with patients with low oxHDL/ ApoAI. The multivariate logistic analysis demonstrated that oxHDL/ApoAI significantly associated with the presence of HRP and significant coronary stenosis (p = 0.01 and 0.01). In the follow-up study including 243 patients for a median period of 1.8 years, univariate cox regression analysis showed that oxHDL/ApoAI, HRP and significant stenosis were significant predictors of cardiovascular events.A high oxHDL/apoAI was associated with the presence of HRP and significant stenosis determined by coronary CT angiography, which can lead to cardiovascular events in patients with suspected stable CAD.
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- 2021
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46. Current spectrum of causative pathogens in sepsis: A prospective nationwide cohort study in Japan
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Naoshi Takeyama, Kiyotsugu Takuma, Shin Ichiro Shiraishi, Yutaka Umemura, Toshihiko Mayumi, Daizoh Saitoh, Seitato Fujishima, Masashi Ueyama, Takehiko Tarui, Akiyoshi Hagiwara, Kohji Okamoto, Yuichiro Sakamoto, Norio Yamashita, Toru Hifumi, Taka-aki Nakada, Hiroshi Ogura, Joji Kotani, Kazuma Yamakawa, Tomohiko Masuno, Shigeki Kushimoto, Yasuhiro Otomo, Hiroto Ikeda, Ryosuke Tsuruta, Toshikazu Abe, Yasukazu Shiino, Atsushi Shiraishi, Satoshi Gando, and Junichi Sasaki
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Adult ,Male ,0301 basic medicine ,Microbiology (medical) ,medicine.medical_specialty ,Cardiovascular infection ,Epidemiology ,030106 microbiology ,Gram-Positive Bacteria ,Blood culture ,lcsh:Infectious and parasitic diseases ,Cohort Studies ,Sepsis ,03 medical and health sciences ,0302 clinical medicine ,Japan ,Internal medicine ,Intensive care ,Gram-Negative Bacteria ,medicine ,Humans ,lcsh:RC109-216 ,Prospective Studies ,030212 general & internal medicine ,medicine.diagnostic_test ,business.industry ,Abdominal Infection ,Bacterial Infections ,General Medicine ,Middle Aged ,medicine.disease ,Antimicrobial ,Anti-Bacterial Agents ,Intensive Care Units ,Infectious Diseases ,Cohort ,Female ,business ,Cohort study - Abstract
Background There is no one-size-fits-all empiric antimicrobial therapy for sepsis because the pathogens vary according to the site of infection and have changed over time. Therefore, updating knowledge on the spectrum of pathogens is necessary for the rapid administration of appropriate antimicrobials. Objective The aim of this study was to elucidate the current spectrum of pathogens and its variation by site of infection in sepsis. Methods This was a prospective nationwide cohort study of consecutive adult patients with sepsis in 59 intensive care units in Japan. The spectrum of pathogens was evaluated in all patients and in subgroups by site of infection. Regression analyses were conducted to evaluate the associations between the pathogens and mortality. Results The study cohort comprised 1184 patients. The most common pathogen was Escherichia coli (21.5%), followed by Klebsiella pneumoniae (9.0%). However, the pattern varied widely by site of infection; for example, gram-positive bacteria were the dominant pathogen in bone/soft tissue infection (55.7%) and cardiovascular infection (52.6%), but were rarely identified in urinary tract infection (6.4%). In contrast, gram-negative bacteria were the predominant pathogens in abdominal infection (38.4%) and urinary tract infection (72.0%). The highest mortality of 47.5% was observed in patients infected with methicillin-resistant Staphylococcus aureus, which was significantly associated with an increased risk of death (odds ratio 1.88, 95% confidence interval 1.22–2.91). Conclusions This study revealed the current spectrum of pathogens and its variation based on the site of infection, which is essential for empiric antimicrobial therapy against sepsis.
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- 2021
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47. Intermittent Purpura Development Associated with Leukocytoclastic Vasculitis Induced by Infliximab for Crohn's Disease
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Riruke Maruyama, Norihisa Ishimura, Akihiko Oka, Mai Fukunaga, Kousaku Kawashima, Noriyoshi Ishikawa, Shunji Ishihara, Yoshiyuki Mishima, Satoshi Kotani, Naoki Oshima, Kenichi Kishimoto, and Hiroki Sonoyama
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Immunoglobulin A ,medicine.medical_specialty ,Necrosis ,Case Report ,030204 cardiovascular system & hematology ,03 medical and health sciences ,0302 clinical medicine ,Crohn Disease ,immune system diseases ,Internal Medicine ,medicine ,Humans ,Adverse effect ,Crohn's disease ,biology ,Tumor Necrosis Factor-alpha ,leukocytoclastic vasculitis ,business.industry ,General Medicine ,medicine.disease ,Dermatology ,Infliximab ,Purpura ,purpura ,biology.protein ,Vasculitis, Leukocytoclastic, Cutaneous ,030211 gastroenterology & hepatology ,Tumor necrosis factor alpha ,medicine.symptom ,infliximab ,Vasculitis ,business ,medicine.drug - Abstract
Anti-tumor necrosis factor (TNF) α agents, widely used for the treatment of Crohn's disease (CD), can sometimes induce skin-associated adverse events, which mainly include psoriasis-like eruptions, eczema, and cutaneous infections. In contrast, purpura caused by vasculitis is rarely seen. We herein report a unique case of leukocytoclastic vasculitis induced by infliximab administered for CD in which intermittent purpura development was noted. Fluorescent immunostaining showed no immunoglobulin A deposition on the vessel walls. No purpura was initially seen after starting infliximab, but it appeared approximately 10 months later; however, administration did not have to be discontinued, and the condition was later resolved. The present findings provide important details regarding vasculitis induced by anti-tumor necrosis factor-α agent administration.
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- 2021
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48. Coffee consumption and mortality in Japan with 18 years of follow-up: the Jichi Medical School Cohort Study
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N. Nakaya, Toyohiro Hamaguchi, Kazunori Kayaba, Kazuhiko Kotani, Shizukiyo Ishikawa, T. Sakamaki, and M. Namekawa
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Adult ,Male ,Coronary Disease ,Coffee consumption ,Coffee ,Cohort Studies ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Japan ,Cause of Death ,Neoplasms ,Surveys and Questionnaires ,medicine ,Humans ,Prospective Studies ,030212 general & internal medicine ,Prospective cohort study ,Stroke ,Schools, Medical ,Aged ,Proportional Hazards Models ,Aged, 80 and over ,Proportional hazards model ,business.industry ,030503 health policy & services ,Hazard ratio ,Public Health, Environmental and Occupational Health ,Cancer ,General Medicine ,Middle Aged ,medicine.disease ,Confidence interval ,Female ,0305 other medical science ,business ,Demography ,Cohort study - Abstract
Objective Coffee consumption can be expected to reduce mortality due to cardiovascular diseases and cancer. This study tested the hypothesis of an inverse association between coffee intake and all-cause mortality and mortality due to cancer, coronary heart disease, or stroke. Study design Prospective cohort study. Methods We analyzed data from the Jichi Medical School Cohort Study, Japan, enrolling 9946 subjects (men/women: 3870/6,076, age: 19–93 years) from 12 communities. A food frequency questionnaire assessing the subjects’ daily coffee consumption was used. Results During an average follow-up of 18.4 years, the total number of deaths was 2024, including 677 for cancer, 238 for coronary heart disease, and 244 for stroke. Cox proportional hazards models were used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) of all-cause mortality and cause-specific mortality due to cancer, coronary heart disease, and stroke. Overall, no significant association was shown between coffee consumption and all-cause mortality. In the cause-specific mortality analyses, stroke mortality was significantly lower in those who consumed 1–2 cups of coffee daily (HR [95% CI]: 0.63 [0.42–0.95]) than in those who do not consume coffee, and this association occurred only in men. Conclusion This study showed no significant association between coffee consumption and all-cause mortality. A U-shaped association between coffee consumption and stroke mortality with a 37% lower stroke mortality, only significant in men who consume 1–2 cups of coffee daily was observed. It is necessary to examine the possibility of intervention studies to reduce stroke mortality through coffee consumption
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- 2021
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49. Technical and Conceptual Review on the L5-S1 Oblique Lateral Interbody Fusion Surgery (OLIF51)
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Seiji Ohtori, Yasuhiro Shiga, Gen Inoue, Hiroshi Takahashi, Yoshihisa Kotani, Nakajima Takao, Shunsuke Fujibayashi, Richard A. Hynes, Masao Koda, Masahiro Inoue, Satoshi Maki, Masato Tanaka, Junichi Nakamura, Kazuhide Inage, Takeo Furuya, Tsutomu Akazawa, Masayuki Miyagi, Sumihisa Orita, Shigeo Hagiwara, Yawara Eguchi, Takahiro Iida, and Yasuchika Aoki
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Retrograde ejaculation ,medicine.medical_specialty ,Fusion surgery ,business.industry ,lcsh:Surgery ,Less invasive ,complication ,lcsh:RD1-811 ,Review Article ,Perioperative ,medicine.disease ,Oblique lateral ,Surgery ,Lumbar ,Great vessels ,Minimally invasive surgery ,Oblique lateral interbody fusion (OLIF) ,medicine ,Orthopedics and Sports Medicine ,Anterior lumbar interbody fusion (ALIF) ,Neurology (clinical) ,retrograde ejaculation ,business ,vascular injury - Abstract
Lumbar lateral interbody fusion (LLIF) has been gaining popularity among the spine surgeons dealing with degenerative spinal diseases while LLIF on L5-S1 is still challenging for its technical and anatomical difficulty. OLIF51 procedure achieves effective anterior interbody fusion based on less invasive anterior interbody fusion via bifurcation of great vessels using specially designed retractors. The technique also achieves seamless anterior interbody fusion when combined with OLIF25. A thorough understanding of the procedures and anatomical features is mandatory to avoid perioperative complications.
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- 2021
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50. Surgical Site Infection Following Primary Definitive Fusion for Pediatric Spinal Deformity
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Tsutomu Akazawa, Kota Watanabe, Noriaki Kawakami, Katsushi Takeshita, Ryo Sugawara, Yuki Taniguchi, Kenichiro Kakutani, Satoshi Suzuki, Teppei Suzuki, Keita Nakayama, Kenta Fujiwara, Haruhisa Yanagida, Morio Matsumoto, Koki Uno, Toru Yamaguchi, Takuya Yamamoto, Satoru Demura, Tatsuya Sato, Tetsuya Ohara, Toshiaki Kotani, Kei Watanabe, Hideki Murakami, and Toru Hirano
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Male ,medicine.medical_specialty ,Univariate analysis ,business.industry ,Incidence (epidemiology) ,Kyphosis ,Urinary incontinence ,Scoliosis ,Odds ratio ,Guideline ,medicine.disease ,Spinal Fusion ,Risk Factors ,Internal medicine ,medicine ,Etiology ,Humans ,Surgical Wound Infection ,Orthopedics and Sports Medicine ,Neurology (clinical) ,medicine.symptom ,Child ,business ,Retrospective Studies - Abstract
STUDY DESIGN A retrospective multicenter study. OBJECTIVE To determine the surgical site infection (SSI) rate, associated risk factors, and causative pathogens in pediatric patients with spinal deformity. SUMMARY OF BACKGROUND DATA There have been no extensive investigations of the risk factors for SSI in Japan. METHODS Demographic data, radiographic findings, and the incidence of SSI were retrospectively analyzed in 1449 pediatric patients who underwent primary definitive fusion surgery for spinal deformity at any of 15 institutions from 2015 to 2017. SSI was defined according to the US Centers for Disease Control and Prevention guideline. RESULTS The incidence of all SSIs was 1.4% and that of deep SSIs was 0.76%. The most common pathogenic microbes were methicillin-resistant staphylococci (n = 5) followed by gram-negative rods (n = 4), methicillin-sensitive staphylococci (n = 1), and others (n = 10). In univariate analysis, younger age, male sex, a diagnosis of kyphosis, type of scoliosis, American Society of Anesthesiologists (ASA) class ≥3, mental retardation urinary incontinence, combined anterior-posterior fusion, greater magnitude of kyphosis, three-column osteotomy, use of blood transfusion, and number of antibiotic administration were associated with the likelihood of SSI (all P
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- 2021
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