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BACKGROUND: A good nutritional status will improve health for average growth and physical development, and intelligence. The prevalence of schoolchildren (5–12 years) with malnutrition status based on brachial fat area is 11.2%, and the number of elementary schoolchildren with malnutrition status in Cibereum village is 107 students. The government has a School Child Supplement Program to meet schoolchildren’s dietary needs. It is necessary to have additional food for schoolchildren to improve their nutritional status, especially for students with low nutritional quality. AIM: The purpose of this study was to determine the effect of carrot catfish dumplings on the bodyweight of elementary school students with poor nutritional status as a form of supplementary food for schoolchildren. METHODS: Researchers conducted this study in January 2020 at Elementary Schools at the Cibereum Health Center (SDN Cibeureum 5, Cibeureum 7, and Cibereum Mandiri 2) with a sample of 25 people. The research design used is quasi-experimental using one-group pretest-posttest and statistical tests using the Wilcoxon test. RESULTS: The research test results showed that carrot catfish dumplings affected elementary school students’ body weight with low nutritional status. CONCLUSION: Carrot catfish dumplings can increase students’ energy intake and protein intake so that there is an increase in the average body weight of the sample by 0.55 kg. Suggestions for further research to conduct a similar study using a control group as the comparison group.

In patients with type 2 diabetes mellitus (Type 2 DM), glycemic control plays an essential role in reducing macro- and microvascular complications. The earliest marker for diabetic nephropathy is the presence of albuminuria. Meanwhile, HbA 1c has been recognized as a marker of glycemic control in the blood. This study aimed to identify the correlation between HbA 1c and albuminuria in type 2 DM. This was a cross-sectional study involving 100 patients with type 2 DM aged 40–70 years visiting Dr. Soetomo Hospital, Surabaya, Indonesia. Secondary data from medical records of type 2 DM patients undergoing HbA 1c and albuminuria examinations from January to December 2015 were used. The mean age of subjects was 55.4 ±8.7 years, with the majority (55%) being of female gender. The mean HbA 1c concentration was 9.8±2.4%. Most subjects (83%) had an HbA 1c level of ≥7 %. Albuminuria was found in the majority of the subjects (78%), where 33% of them had positive 1 albuminuria. The Spearman correlation test showed a positive strong significant correlation between HbA 1c and albuminuria, with r=0.865 and p

Background: Uses of HbA1c compared with glycated albumin as an indicator of glycemic control for hemodialysis patients(HD) needs to be evaluated. HbA1c has some limitations when used for HD because its results can falsely low or falsely high. It can be missunderstood if clinicians use HbA1c as glycemic control. Objective: This study aimed to evaluate correlation between HbA1c and GA in HD patients with Diabetes Mellitus (DM). Methods: This study was a cross sectional study conducted on November 2016 until January 2017. Its samples were obtained from 43 patients in HD with DM, fullfilling inclusion and exclusion criteria, located in a private hospital at east Jakarta. The HbA1c was measured by using a turbidimetric inhibition immunoassay method, and the GA was measured by using an enzimatic colorimetric method. In addition, a test of Pearson correlation was used to determine the correlation between HbA1c and GA with a significance of p

Introduction: Dengue hemorrhagic fever is one of the population's health issues in Indonesia, with an increasing number of sufferers as the disease spreads. The cases rose dramatically in Panji Village, with a significant spike in cases per year. In 2018 there were 16 cases, in 2019 it increased to 177 cases and in 2020 until February 122 cases were recorded. Mosquito nest eradication is the most reliable, safe, and cost-effective method of eliminating dengue fever vectors. The aim of this study is to know relationship the level of knowledge and behavior regarding mosquito nest eradication in Panji Village. Methods: The design used was descriptive correlation with a cross sectional approach. The population of this study is the population living in the Banjar area, Dinas Dangin Pura Panji Village Sukasada, Bali with 1222 residents, after entering the Slovin’s formula, 400 samples were obtained using purposive sampling technique. The instrument used to collect data in this study was a questionnaire sent via google form. Test the relationship using the Pearson test. Results: Most people have less knowledge and behavior and when viewed from the correlation test, a significant value of p = 0.000 is obtained with a value of r = 0.524 which means that the relationship is moderate and has a positive value. Conclusion: There is a moderate and positive relationship between knowledge and behavior in the Eradication of Mosquito Nests.

Latar Belakang : Kanker serviks atau kanker leher rahim merupakan kanker pembunuh nomor dua di dunia. Pemerintah telah berupaya untuk mengatasi kanker serviks dengan metode inspeksi visual asam asetat (IVA). Faktor yang dapat mempengaruhi seseorang untuk melakukan IVA antara lain pengetahuan, sikap, budaya dan dukungan petugas kesehatan. Tujuan penelitian ini untuk mengetahui perbedaan faktor yang mempengaruhi wanita usia subur (WUS) yang pernah melakukan pemeriksaan IVA dan belum pernah tes IVA. Metode : mengguanakan analitik observasional dengan pendekatan cross sectional . Jumlah sampel sebanyak 108 wanita usia subur dengan teknik purposive sampling yang memnuhi kriteria inklusi dan eksklusi. Untuk mengetahui tingkat signifikan, data yang terkumpul akan diuji statistik Chi-Square dan Fisher Exact Test pada tingkat kemaknaan 0,05. Hasil: faktor yang memiliki perbedaan yang bermakna antara wanita usia subur yang pernah melakukan dan belum pernah melakukan pemeriksaan IVA antara lain pengetahuan ( p= 0,002), Budaya ( p = 0,021), dukungan petugas kesehatan ( p= 0,010). Sedangkan sikap ( p = 1,000) tidak terdapat perbedaan yang bermakna. Kesimpulan: perbedaan faktor yang mempengaruhi WUS yang pernah dan belum pernah tes IVA di wilayah puskesmas Sidotopo adalah pengetahuan, budaya dan dukungan petugas kesehatan. Abstract Background : Cervical cancer is the second leading deathly woman disease in the world. The Indonesian government has been trying through visual inspection of the cervix with acetic acid (VIA). There are some factors influencing women to undergo VIA such as knowledge, behaviour, culture and the support of medical workers. Thus, this research was aimed at finding significance differences among reproductive women undergoing and not undergoin g. Method : This research employed Observational Analytic using cross sectional approach. The s ample of this research was 10 8 women of reproductive age . Purposive sampling was employed as a technique which met inclusion and eksclusion criteria. To be able to find out the significance, the data collected was tested in the statistical test chi square of 0.05 significance level. Result : Factors like knowledge (p= 0,002), culture (p= 0,021), and support of medical workers (p= 0,010) showed significance difference among reproductive women undergoing and not undergoing VIA while behaviour (p= 1,000) showed no significance difference. Conclusion : the differences among reproductive women undergoing and not undergoin gVIA in region of puskesmas Sidotopo was knowledge, culture and the support of medical workers.

LATAR BELAKANG Dekade terakhir menunjukkan neck pain pada remaja semakin meningkat, bersamaan dengan meningkatnya penggunaan gawai (gadget). Seiring perkembangan zaman, gawai menjadi kebutuhan dan gaya hidup masyarakat luas. Pelajar menjadi pasar terbesar dalam penggunaan gawai sehubungan dengan kebutuhan belajar yang memerlukan akses Internet. Salah satu faktor penyebab neck pain pada pengguna gawai adalah intensitas penggunaan gawai yang mempengaruhi lamanya posisi fleksi pada otot leher. Tujuan penelitian ini adalah untuk mengetahui hubungan intensitas pemakaian gawai dengan neck pain pada usia 15-20 tahun. METODE Penelitian ini merupakan studi observasional dengan desain cross sectional yang mengikutsertakan 164 pelajar SMAN 28 Jakarta dan Fakultas Hukum Universitas Trisakti. Data dikumpulkan dengan cara pengisian kuesioner yang meliputi usia, jenis kelamin, intensitas pemakaian gawai dan keluhan neck pain. Penilaian neck pain menggunakan NRS (Numeric Rating Scale). Analisis data dilakukan dengan uji Chi-square dengan tingkat kemaknaan p56 jam/minggu dijumpai pada 109 subjek (66.5%). Keluhan neck pain dijumpai pada 138 subjek (84.1%). Uji Chi-square menunjukkan terdapat hubungan yang bermakna antara intensitas penggunaan gawai dengan neck pain pada usia 15-20 tahun dengan nilai p=0.004. KESIMPULAN Terdapat hubungan yang bermakna antara intensitas penggunaan gawai dengan neck pain pada usia 15-20 tahun.

Background: The Covid-19 pandemic caused great stress, especially for health workers which resulted in moderate or severe symptoms of depression, anxiety, insomnia, and more serious stress. Gender is very influential, given the differences in biological and social roles between men and women. Gender differences between men and women allow for variations in strategies in responding to mental health to increase awareness and self-management, so as to avoid mental health problems during the Covid-19 pandemic. Subjects and Method: Meta-analysis was performed by searching articles from Google Scholar, PubMed, Scopus, Springer Link, and health-related databases. The keywords used in the article search were "health workers" AND "covid-19" AND "mental health". The inclusion of the criteria in this study is a full-text article, from 2019-2021, with a study design cross-sectional. The article analysis was carried out using RevMan 5.3. Results: There were 5 articles analyzed, the results showed no significant difference between gender and mental health responses among health workers during the Covid-19 pandemic (aOR= 1.12; 95% CI= 0.59-2.13; p=0.01). Conclusion: Not significant between primary studies regarding gender differences in mental health responses to health workers during the Covid-19 pandemic. Keyword s : health workers, covid-19, mental health Correspondence: Riyesti Hero Fresna, Purwantoro Special Edu­cational School. Wonogiri Regency, Central Java 57695. E-mail: riyestiherofresna01@g­mail.com. Mobile +628­1227831443. Journal of Health Policy and Management (2021), 06(02): 130-138 https://doi.org/10.26911/thejhpm.2021.06.02.05

Introduction: Quality of life is a significant aspect of care among the elderly with HIV/AIDS. The aging process affects their physical, physiological, and social function. Depression due to perceived stigma from the community also influences their quality of life. This study aimed to analyze the correlation between depression and stigma on the quality of life among the elderly with HIV/AIDS. Methods: This was a cross-sectional study employed 67 participants were selected by purposive sampling. Results: Results showed that the majority of participants experienced depression (64.2%) and stigma (76.1%), but they are still classified on good quality of life category (64.2%). Analysis showed that there was a significant correlation between quality of life and depression, & and stigma (p=0.021, p=0.031, α=0.05). Result from logistic regression statistical analysis also revealed that stigma and depression affected the poor quality of life after controlled by gender, occupational status, education, clinical stadium, comorbidities, duration of disease, living and marital status, with the p-value 0.029 and 0.014 (CI=95%), respectively. Conclusion: Promotive and preventive efforts required to be implemented in reducing stigma on the elderly with HIV/AIDS. Screening program also would help prevent depression among this vulnerable group.

Introduction: Asthma is a reversible disease characterized by airway obstruction which tends to relapse due to certain factors. Asthma required adequate management to minimalize the frequently of the symptoms occurred and not become a burden for its sufferers. Pursed-Lip breathing (PLB) is an effective breathing technique used in managing asthma symptoms. This study aimed to know the difference in the respiratory rate (RR) before and after the PLB exercise on the asthma patients in Pulmonary Clinic, TNI AU dr. M Salamun Bandung Hospital. Method: A quasi-experimental study with a non-equivalent control group approach was used for this experiment. Of 106 asthma patients, 51 patients who met the inclusion criteria were chosen to participate in this study. The participants were asked to do a PLB exercise based on the standard operating procedure of PLB provided by the researcher. Results: The data analysis showed that there was a significant difference in the RR before and after the PLB exercise with an average of 23.90 and 19.94 (p

It has been estimated that deficiency and insufficiency of Vitamin D affect one bilion people worldwide. Vitamin D deficiency can befound not only in countries with four (4) seasons, but also in countries with sunlight exposure all year long The objective of this studywas to know whether vitamin D deficiency can occur in Indonesia as well and to explore the role of vitamin D in people‘s health, althoughIndonesia is a country in the equator region. To avoid long term negative health consequences 25 hydroxyvitamin D/25 (OH) D serumlevel should be between 30 and 100 ng/mL. The main source of vitamin D is by synthesis at the skin which is exposed to ultraviolet Bradiation. The other source of vitamin D is from food. There are a lot of causes of vitamin D deficiency, for example: decreased vitaminD synthesis, nutritional intake of vitamin D, maternal vitamin D stores and exclusive breastfeeding, mal absorption and decreasedsynthesis or increased degradation of 25 (OH) D. From the above factors, decreased vitamin D synthesis is the main cause of vitamin Ddeficiency. The vitamin D deficiency is estimated and plays an important role in multiple disorders, such as: osteoporosis, fracture, cancer,cardiovascular disease, diabetes mellitus, autoimmune disease and infectious disease. A good strategy in managing vitamin D deficiencyis needed in order to solve the related problems.

Rationale: Spinocerebellar ataxia (SCA) 3, also known as Machado-Joseph Disease (MJD), is a neurodegenerative disease which involves cerebellum and its afferent and efferent pathways. Generally, the initial symptoms were gait disturbance, double vision, dysarthria, and vertigo. Patient concerns: a 43-year-old male, with known SCA3, presented hereditary ataxia had mild numbness in his both palms since two years ago. Sensory examination found no abnormality. Nerve Conduction Studies (NCS) showed severe axonal demyelinating sensorimotor peripheral neuropathy. In magnetic resonance imaging atrophy cerebellum with cerebral multiple lacunar infarction were seen. Diagnoses: SCA3 was diagnosed on the basis of clinical features, family pedigree, physical examination, electrophysiology study, neuroimaging, nerve biopsy, and genetic testing results. The electrophysiological manifestations revealed profound axonal demyelinating lesion in peripheral nerves. Genetic analysis was not done yet due to lack of availability of genetic testing in our country at this moment although it is the gold standard for diagnosis. Lessons: SCA3 with peripheral neuropathy represents a specific clinical entity that so far has never been described previously in Indonesia. Abbreviations: SCA3 = Spinocerebellar ataxia, MJD = Machado-Joseph Disease , NCS = Nerve Conduction Studies

The purpose of this study was to analyze effect of linear growth and psychosocial aspects of caregiving on cognitive development of toddlers. Methods: Longitudinal studies were carried out from pregnancy to three years old children in Bogor. The collected data included body height, nutritional status based on height by age index, morbidity, aspects of caregiving, and cognitive development of three years old children. Linear growth data is obtained from anthropometric measurements of height at birth, age six months, and twelve months measured using a length measuring instrument body with a precision level of 0.10 cm. Caregiving of psychosocial aspect divided by some characteristics, such as learning stimulation, language stimulation, academic stimulation, modelling, warmth and acceptance, caregiving variation, punishment & acceptance and physical environment. Cognitive development measurement was divided into two categories, namely delay and appropriate to age. Multiple logistic regression was applied to analyze the effects. Toddlers who were born stunted and continued to be stunted until they were three years old had lower cognitive development than stunted newborns that were able to achieve normal height at three years old. In addition, children who experience caregiving with poor psychosocial aspects had lower cognitive development than those with good caregiving. This study highlighted the importance efforts to improve nutritional status of children as well as providing good care for them.

Poor nutritional status or stunting still becomes a public health problem in Indonesia, with prevalence of 37.2% in 2013. Some research results show that stunted children have lower cognitive development than normal children. This study aims to assess whether there is an effect of giving multiple-nutrient biscuits and psychosocial parenting education on height and development of children under the age of three (toddlers). This study used quasi experimental design. The treatment was given for 2 mo to 28 stunted children who were divided into 3 groups, namely: (1) multiple-nutrient biscuits (2) psychosocial parenting education (3) multiple-nutrient biscuits and psychosocial parenting education. Multiple-nutrients biscuit was given 12 pieces a day for 2 mo. Meanwhile, psychosocial parenting education was given direcly by psychologist in the form of lectures, brainstorming and role play. In order to identify the effect of treatment on children's height and development, the data obtained was analyzed using paired t-test, while the analysis of differences between treatment groups was carried out using analysis of variance (ANOVA). The results showed that giving psychosocial parenting education significantly increased height, children's nutritional status based on height by age index, and improved cognitive development among toddlers. Giving multiple-nutrient biscuits and psychosocial parenting education significantly increased height and cognitive development among toddlers. In order to overcome children's growth and development problem, nutrition interventions need to be carried out along with the provision of education about maternal parenting to children.

Spinocerebellar ataxia (SCA) is an autosomal dominant hereditary disease with progressive course, and no causal therapy. Diagnostics are still challenging, due to facility and protocols, and so as in Indonesia. As a national referral center, Dr. Hasan Sadikin Central General Hospital has received a lot of patients from all over Indonesia, particularly from Western Java. Study related to SCA (including clinical and genetic profile) is still limited in Indonesia. We identified index patients from three families with ataxia, hence intend to determine their clinical and genetic pattern. The hereditary pattern is autosomal dominant. Scale for the assessment and rating of ataxia (SARA) shows mild and moderate ataxia. Inventory of non-ataxia signs (INAS) scores of the patients were 3, 5 and 6. Montreal cognitive assessment-Indonesian version (MOCA-INA) shows only one patient has mild cognitive impairment, despite young age. Barthel index shows 1 subject has moderate dependency. Mutation in Ataxin3 polyQ repeats shows pathologically long CAG repeats, 72,10; 72,10; and 72,23 respectively in mutant and wild type allele. We diagnosed the index patients with spinocerebellar ataxia type 3. This study is the first case series study in Indonesia. The hereditary pattern is clearly shown as an autosomal dominant ataxia. The clinical and genetic profile was varied, and the symptom is progressive and deteriorates overtime, including wide based gait, speech problem, motor and sensor complaint, and cognitive decline complaint. Despite the same polyQ stretch length, the onset and clinical characteristics of patients are diverse., Autosomal dominant, Familial ataxia, Indonesia, Polyglutamine, Spinocerebellar ataxia.

Background Vitamin D insufficiency is associated with obesity and central obesity, which is in turn associated with the accumulation of visceral fat. Visceral fat secretes adiponectin which has a role in the pathogenesis of the metabolic syndrome, diabetes mellitus and cerebrovascular disease. The aim of this study was to determine the relationship between serum 25-hydroxy vitamin D [25(OH)D] level and adiponectin level in adults with central obesity. Methods This study was a cross sectional study with 80 subjects with central obesity and 80 healthy subjects as controls. The age of the subjects ranged from 55 to 65 years. The data collection included anthropometry and blood biochemistry (lipid profile, fasting blood glucose, 25(OH)D, and adiponectin). The data were analyzed using independent t test with p

Background Sleep is needed by the human body so that the performance of body remains optimal when the body is awake, especially during work. Informal workers often work without clear regulations, with inadequate equipment and poor work environment, and pay little attention to occupational health and safety factors. The existence of large work demands with unclear work system arrangements will certainly result in a mental workload in these workers. The objective of this study was to determine the relationship between mental workload and sleep patterns of workers in the informal garment sector. MethodsA cross-sectional study involving 225 informal garment workers was conducted between December 2018 and May 2019. Data collection included respondents’ demographics, job characteristics, measurement of mental burden and disturbances in sleep patterns. The sleep pattern used the PSQI (Pittsburgh Sleep Quality Index) instrument and the mental burden used the Rating Scale Mental Effort (RSME). A multiple linear regression analysis was used to analyze the data. ResultsThe mean sleep quality was 5.40 ± 2.54. Multiple linear regression test found that mental workload correlated significantly with sleep quality of workers (β=0.016, p=0.012).ConclusionThis study demonstrated that heavy mental workload decreases the quality of sleep in informal garment workers. A good work system management is required so that workers are assigned that portion of the task that is commensurate with their capacity.

BACKGROUND: Ficus deltoidea Jack. leaves have a great potential as traditional medicine, but the safety level of its use is still unknown. AIM: This study aimed to determine the phytochemical contents of the ethanol extract of F. deltoidea leaves and evaluate the level of safety and toxicity through acute and subchronic toxicity tests in mice (Mus musculus). METHODS: The ethanol extract of F. deltoidea leaves was determined for phytochemical contents such as alkaloids, phenolics, flavonoids, coumarin, steroids, saponins, carotenoids, and tannins. In the acute toxicity test, 10 male mice were divided into a control group and the extract treatment group with 2000 mg/kg body weight (BW) dose for 14 days to identify signs of toxicity and mortality. Meanwhile, in the subchronic toxicity test, 25 male mice were divided into control and four treatment groups with various doses (125, 250, 500, and 1000 mg/kg BW), respectively, for 28 days. The toxicological effect was evaluated by observing behavior, signs of toxicity, and changes in BW. At the end of the treatment, hematological and biochemical evaluations were also measured. RESULTS: The results showed that the ethanol extract of F. deltoidea Jack leaves qualitatively contains alkaloids, phenolic, flavonoids, coumarin, and steroids, whereas quantitatively total phenolics, flavonoids, and IC50 were 107.6583211 μg GA/mg, 175.9103641 μg CE/mg, and 103.7484 μg/mL. Moreover, 2000 mg/kg BW dose resulted in no symptoms of toxicity and mortality, indicating that the 50% lethal dose (LD50) was above 2000 mg/kg BW. Meanwhile, there were no behavioral changes, significant differences in weight changes, hematological parameters, and serum biochemistry of mice in subchronic toxicity tests. CONCLUSION: The present study shows that acute and subchronic oral administration of the ethanol extract of F. deltoidea leaves for male mice does not induce clinical symptoms of toxicity or mortality. The LD50 of the ethanol extract of F. deltoidea leaves for mice >2000 mg/kg is considered as practically non-toxic.

Anxiety is one of the factors influencing students’ speaking performance in the classroom. A video making task is an alternative strategy that can decrease anxiety besides it provides a positive influence on students’ self-assessment of speaking task. Hence, the objective of this study was to describe how video making task could decrease students’ anxiety in speaking class. This study used a descriptive qualitative method in which the data source was the students’ performance in video to require the task of procedure text presentation in speaking class. The data were collected by using observation and interview. And the result of the observation of the video showed that most of the students seemed less anxious and more relaxed in explaining the assigned materials. In the interview, the students also said that they felt more confident in presenting the task. In conlusion, the video making task could decrease students’ anxiety in students’ speaking performance.

Objective The prevalence of Escherichia coli including from ice cubes in Indonesia is quite high. Unfortunately, little is known about the genetic diversity of E. coli from ice cube production site. Genotypic variation in E. coli populations is a major barrier to control public health risk associated with foodborne pathogen. The aims of this study were to analyze the genotypic diversity of E. coli strains isolated from various samples in order to determine the genetic relationship between those strains. This study is also important to understand the occurrence, prevalence and profile picture of different pathogenic E. coli in various sources which potentially cause disease. Results Enterobacterial repetitive intergenic consensus (ERIC) and repetitive extragenic palindromic polymerase chain reaction (REP-PCR) dendrogram showed high genetic diversity of 120 E. coli isolates in majority of sampling sites. DNA fingerprint patterns showed 26 and 21 clusters with 11 and 3 fingerprints individual lineages for ERIC and REP-PCR respectively. There was no correlation observed between phylogenetic relationship and virulence genes. The result indicated a variation of E. coli isolates in ice cube manufacturers. ERIC-PCR method is more discriminative compared with REP-PCR to analyze the genetic diversity of E. coli from ice cubes production sites.

The Gold standard for the evaluation of the glomerular filtration rate (GFR) is inulin clearance, but in widespread use is prevented by several technical difficulties. The most commonly used marker for GFR is serum creatinine alone or in conjunction with 24 hoururine collection for determination of creatinine clearance, but these marker have several limitation include following: influence of age,sex, muscle mass on endogenous creatinine production, dietary intake and the difficulties of 24 hour urine collection. Fifty six patientwith chronic renal failure and 53 control had analyze for serum creatinin, creatinine clearance and serum cystatin C. The chronic renalfailure patient aged range from (64 + 14.54) year and the control group aged range from (62.5+ 17.5) year. The proposed of this studywas to compare cystatin C with another parameter for renal function test. The result showed that in control group serum creatinineand creatinine clearance had influence with age, sex and body mass index, but serum cystatin C was not. The normal value of cystatinC was (0.85 + 0.13) mg/dL In chronic renal failure group there were significant correlation between level of cystatin C with creatininclearance (p = 0.000, r = 0.69). The level of cystatin C increase higher than serum creatinine in patient with low clearance creatinine.In control group we were determined low creatinine clearance in patient with normal serum creatinine and cystatin C.

BackgroundThe prevalence of diabetes in Indonesia continues to increase and causes many complications. Fruits of Phaleria macrocarpa (Scheff.) Boerl. (PM) are used in the traditional health system of the Indonesians, as effective remedy in the management of diabetes mellitus. The aim of this study was to evaluate the effect and magnitude of doses of PM dry fruit extract (PME) on blood glucose levels in healthy adults.MethodsThis research was of pre-posttest design involving 30 healthy volunteer subjects aged 20-55 years receiving glucose loads. At pre-test the subjects were given orally 75 g glucose, and at post-test they were given PME at doses of 125 mg and 250 mg. Data collection included anthropometric examination and blood glucose level. The area under the curve (AUC) of blood glucose levels was measured at 0, 15, 30, 60, 120 and 180 minutes. Data analysis was performed using paired t-test with p

Physiological alterations during pregnancy generate higher risk of pulmonary edema and acute respiratory failure. Respiratory failure occurs in 0.2% pregnancy, particularly in postpartum period. Respiratory failure can be developed by specific conditions related to pregnancy, such as preeclampsia and peripartum cardiomyopathy. We present the case of 34-year-old female, with 36 weeks of pregnancy, that came with shortness of breath since an hour before admitted. Patient also had vaginal discharge in the last two hours before admitted. Fetal movement was active. Shortness of breath was accompanied with cough. Physical examination revealed hypertension (160/110 mmHg) and rales on both lungs. Blood gas analysis showed severe hypoxemia. Patient were intubated and underwent C-section afterwards. Chest x-ray showed heart enlargement. Echocardiography result showed fraction ejection 25%, global hypokinetic, mild mitral and tricuspid regurgitation, with conclusion of peripartum cardiomyopathy. This case illustrates respiratory failure in severe preeclampsia and peripartum cardiomyopathy. This condition leads to acute pulmonary edema that impairs ventilation/perfusion process. Mechanical ventilation can assure adequate oxygen delivery. Non-invasive ventilation (NIV) is well suited to short-term ventilatory support, and avoids the potential complications of endotracheal intubation and the associated sedation. (J Respir Indo. 2017; 37(4): 325-36)

Introduction: Ice can be contaminated by pathogenic bacteria. This study aimed to identify critical points in iced beverage production and distribution lines to examine the presence of pathogenic bacteria in a beverage and its processing environment, as well as when water and ice used as main ingredients. Methodology: The critical points were determined using the principles of Hazard Analytical Critical Control Point (HACCP) to analyze each processing and distribution step from the survey. Samples collected from the points of concern based on the critical points that were found were tested for pathogens by conventional method and molecular method using primers and polymerase chain reaction (PCR). Results: Escherichia coli was found in 6.34% of samples, and 0.7% of them were confirmed as enterotoxigenic Escherichia coli (ETEC) by PCR. Vibrio cholerae was found in in 0.7% of water samples used to make iced beverages and in ice production, as well as in 2.12% of distribution and production tools. Salmonella Typhimurium was found in 1.4% of water samples used to make ice and ice products. Staphylococcus aureus was found in 2.02% of the surfaces of ice distribution and production tools and in 5.05% of production and distribution workers’ hands. S. aureus counts ranged from 2.4×102 - 3.5×102 colonies/100 cm² surface area and 1.9×10¹ - 3.7×102 colonies/workers’ hands. Conclusion: Control on many critical points in iced beverage processing and distribution is required so that the beverages are safe for consumption.

Malaria is an infectious disease caused by plasmodium that lives and breeds in the red blood cells, transmitted by the Anopheles mosquito. During this time, the paramedics to diagnose symptoms use any imagery that is done manually. In the identification analysis of the malaria parasite cell infection, there is a possibility of human error factor done by paramedics because of the number of samples analyzed. This case is because the human eye tends to be tired while working continuously, leading to misclassification and treatment that is not right. Therefore, it takes a computer-based system that facilitates image processing to paramedics or laboratory technicians to identify the parasite cells and reduce human error instances. This research conducted on identification of the thresholding and watershed of segmentation method for three types of plasmodium parasite, namely Plasmodium falciparum, Plasmodium malaria, and Plasmodium vivax. This study offered modifications thresholding and watershed algorithm. The results showed the success of the technique that can effectively segment on the three types of Plasmodium malaria, which has an accuracy rate above 90% as well as the results of the computation time between the thresholding method could segment imagery for 1-2 seconds and the watershed method intelligent segmented representation for 3-4 seconds.

Body image distortion has been linked with mind, emotion, sensation and strongly related to size, and shape of individual performance. This research aimed to investigate the perception of body image for adolesscent in the second grade of senior high school in SMAN 1 Bogor. A qualitative design was used to conduct this research by using indepth interview with phenomenology approach. Six students, who were all women, consist of three students were overweight/obese and the other were lean. All of students were interviewed regarding their perception related three domain areas which were: body perception, perception of current body and efforts for achieving the ideal body composition shape. The findings indicated the three student who were overweigt/obese pointed out that they were happy and accepted with their performance but they were not better performing. The other of three student who were lean stated that they had many perception with their body image such as: thin, was not good looking,and unbalancing high and weight. Almost all of the students had a similar perception about their body image whether they were overweight/obese and lean. They were not unhappy with their performance, but they had the same opinion about ideal body shape.

In the 200 years since the Sumatran rhinoceros was first scientifically described (Fisher 1814), the range of the species has contracted from a broad region in Southeast Asia to three areas on the island of Sumatra and one in Kalimantan, Indonesia. Assessing population and spatial distribution of this very rare species is challenging because of their elusiveness and very low population number. Using an occupancy model with spatial dependency, we assessed the fraction of the total landscape occupied by Sumatran rhinos over a 30,345-km2 survey area and the effects of covariates in the areas where they are known to occur. In the Leuser Landscape (surveyed in 2007), the model averaging result of conditional occupancy estimate was ψ(SE[ψ]) = 0.151(0.109) or 2,371.47 km2, and the model averaging result of replicated level detection probability p(SE[p]) = 0.252(0.267); in Way Kambas National Park--2008: ψ(SE[ψ]) = 0.468(0.165) or 634.18 km2, and p(SE[p]) = 0.138(0.571); and in Bukit Barisan Selatan National Park--2010: ψ(SE[ψ]) = 0.322(0.049) or 819.67 km2, and p(SE[p]) = 0.365(0.42). In the Leuser Landscape, rhino occurrence was positively associated with primary dry land forest and rivers, and negatively associated with the presence of a road. In Way Kambas, occurrence was negatively associated with the presence of a road. In Bukit Barisan Selatan, occurrence was negatively associated with presence of primary dryland forest and rivers. Using the probabilities of site occupancy, we developed spatially explicit maps that can be used to outline intensive protection zones for in-situ conservation efforts, and provide a detailed assessment of conserving Sumatran rhinos in the wild. We summarize our core recommendation in four points: consolidate small population, strong protection, determine the percentage of breeding females, and recognize the cost of doing nothing. To reduce the probability of poaching, here we present only the randomized location of site level occupancy in our result while retaining the overall estimation of occupancy for a given area. ψ

Dietary isoflavones are considered to be cardioprotective because of their structural similarity to estrogen. Equol is a metabolite of daidzein that is more potent than daidzein itself. The effect of equol on endothelial function and oxidative stress remains unclear. The objective of this study was to determine the effect of 100 mg/day soy isoflavone supplementation on the following markers: vascular cell adhesion molecule-1 (VCAM-1) and nitric oxide (NO) as markers of vascular endothelial function, and malonyldialdehyde (MDA) as oxidative stress marker in equol-producing postmenopausal women. A stratified randomized double blind controlled trial was conducted among 190 postmenopausal Indonesian women aged 47 to 60 years. They were stratified into equol producers and equol nonproducers. The random allocation of intervention was carried out separately in each stratum. The intervention group received tablets consisting of 100 mg soy isoflavones and calcium carbonate 500 mg, and the control group received 500 mg calcium carbonate. The concentrations of VCAM-1, NO and MDA were measured at baseline and post-supplementation at 6 months. After 6 months of supplementation the MDA concentrations were significantly lower in the soy-isoflavone equol producers compared with equol nonproducers (p=0.021). Similar results were also found for VCAM-1 and NO concentrations, but these were statistically not significant (p = 0.413 and p= 0.724, respectively). This study demonstrates that isoflavone supplementation in postmenopausal women with equol-producer status had a more beneficial effect by decreasing the MDA concentration, but did not improve VCAM-1 and NO concentrations.

Large carnivores living in tropical rainforests are under immense pressure from the rapid conversion of their habitat. In response, millions of dollars are spent on conserving these species. However, the cost-effectiveness of such investments is poorly understood and this is largely because the requisite population estimates are difficult to achieve at appropriate spatial scales for these secretive species. Here, we apply a robust detection/non-detection sampling technique to produce the first reliable population metric (occupancy) for a critically endangered large carnivore; the Sumatran tiger (Panthera tigris sumatrae). From 2007–2009, seven landscapes were surveyed through 13,511 km of transects in 394 grid cells (17×17 km). Tiger sign was detected in 206 cells, producing a naive estimate of 0.52. However, after controlling for an unequal detection probability (where p = 0.13±0.017; ±S.E.), the estimated tiger occupancy was 0.72±0.048. Whilst the Sumatra-wide survey results gives cause for optimism, a significant negative correlation between occupancy and recent deforestation was found. For example, the Northern Riau landscape had an average deforestation rate of 9.8%/yr and by far the lowest occupancy (0.33±0.055). Our results highlight the key tiger areas in need of protection and have led to one area (Leuser-Ulu Masen) being upgraded as a ‘global priority’ for wild tiger conservation. However, Sumatra has one of the highest global deforestation rates and the two largest tiger landscapes identified in this study will become highly fragmented if their respective proposed roads networks are approved. Thus, it is vital that the Indonesian government tackles these threats, e.g. through improved land-use planning, if it is to succeed in meeting its ambitious National Tiger Recovery Plan targets of doubling the number of Sumatran tigers by 2022. Published version