1. Arrhythmic mitral valve prolapse: Diagnostic parameters for high‐risk patients: A systematic review and meta‐analysis
- Author
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Fatima Anwer, Ana P Arcia Franchini, Fotios Kakargias, Priyanka Panday, Pousette Hamid, Beshoy Iskander, and Federico Oliveri
- Subjects
medicine.medical_specialty ,Mitral Valve Prolapse ,High risk patients ,business.industry ,Arrhythmias, Cardiac ,General Medicine ,Odds ratio ,medicine.disease ,QT interval ,Confidence interval ,Sudden cardiac death ,Relative risk ,Internal medicine ,Meta-analysis ,cardiovascular system ,medicine ,Cardiology ,Humans ,Mitral valve prolapse ,cardiovascular diseases ,Cardiology and Cardiovascular Medicine ,business - Abstract
BACKGROUND Although frequently considered a benign condition, new evidence has shown that mitral valve prolapse (MVP) is associated with complex ventricular arrhythmias (VAs) and sudden cardiac death (SCD). Therefore, we conducted a systematic review and meta-analysis of the relevant studies to investigate the parameters that could identify MVP patients at higher risk of experiencing complex VAs. METHOD We performed a systematic literature search of PubMed for potential studies between January 2010 and January 2021. Our meta-analysis included studies comparing MVP patients with complex VAs (A-MVP) and those without (NA-MVP). We used the fixed-effects model to obtain the odds ratio (OR), risk ratio (RR), or mean difference (MD) and 95% confidence interval (CI) for each analyzed parameter. RESULTS Six studies with 848 individuals were included in the meta-analysis. As compared to the NA-MVP patients, A-MVP patients had a higher prevalence of inverted T-wave (OR: 2.73; 95% CI: 1.85-4.02; p
- Published
- 2021