1. Limited Expansion of Human Hepatocytes in FAH/RAG2-Deficient Swine
- Author
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Erek Nelson, Fang Jin, Taofic Mounajjed, Yao Jia, Wei Zhou, Raymond D. Hickey, Aaron J. Johnson, Bruce Amiot, Scott L. Nyberg, Randall S. Prather, Adam J. Wood, Anna Spate, Dong Jin Joo, Min Shi, Kevin D. Wells, Anna Minshew, Ellen L. Larson, Joeseph Lillegard, Piero Rinaldo, Anan Abu Rmilah, Eric M. Walters, Jeffrey L. Platt, Melanie C. Bois, Melissa Samuel, Jaime Glorioso, Kristin M. Whitworth, and Shennen A. Mao
- Subjects
Biomaterials ,Hereditary tyrosinemia ,medicine.anatomical_structure ,Animal model ,RAG2 ,Biomedical Engineering ,medicine ,Cancer research ,Bioengineering ,Biology ,Biochemistry ,Natural killer cell - Abstract
The mammalian liver's regenerative ability has led researchers to engineer animals as incubators for expansion of human hepatocytes. The expansion properties of human hepatocytes in immunodeficient...
- Published
- 2022