Limited Expansion of Human Hepatocytes in FAH/RAG2-Deficient Swine

Authors :: Erek Nelson
Fang Jin
Taofic Mounajjed
Yao Jia
Wei Zhou
Raymond D. Hickey
Aaron J. Johnson
Bruce Amiot
Scott L. Nyberg
Randall S. Prather
Adam J. Wood
Anna Spate
Dong Jin Joo
Min Shi
Kevin D. Wells
Anna Minshew
Ellen L. Larson
Joeseph Lillegard
Piero Rinaldo
Anan Abu Rmilah
Eric M. Walters
Jeffrey L. Platt
Melanie C. Bois
Melissa Samuel
Jaime Glorioso
Kristin M. Whitworth
Shennen A. Mao
Source :: Tissue Engineering Part A. 28:150-160
Publication Year :: 2022
Publisher :: Mary Ann Liebert Inc, 2022.
Abstract: The mammalian liver's regenerative ability has led researchers to engineer animals as incubators for expansion of human hepatocytes. The expansion properties of human hepatocytes in immunodeficient...

Subjects :: Biomaterials
Hereditary tyrosinemia
medicine.anatomical_structure
Animal model
RAG2
Biomedical Engineering
medicine
Cancer research
Bioengineering
Biology
Biochemistry
Natural killer cell

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