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5 results on '"Bogdanova IM"'

1. Proliferative Activity of Mouse Splenocytes in Physiological Pregnancy and in Models of Spontaneous and Muramylpeptide-Dependent Abortions.

Author

Artem'eva KA, Boltovskaya MN, Bogdanova IM, Obernikhin SS, Stepanova II, Stepanov AA, Svitich OA, and Kalyuzhin OV

Subjects
Abortion, Induced methods, Abortion, Spontaneous chemically induced, Abortion, Spontaneous pathology, Animals, Coculture Techniques, Crosses, Genetic, Dendritic Cells drug effects, Dendritic Cells immunology, Dendritic Cells pathology, Embryo Loss chemically induced, Embryo Loss pathology, Female, Gestational Age, Injections, Intraperitoneal, Lymphocytes immunology, Lymphocytes pathology, Macrophages drug effects, Macrophages immunology, Macrophages pathology, Male, Mice, Mice, Inbred BALB C, Mice, Inbred CBA, Mice, Inbred DBA, Pregnancy, Primary Cell Culture, Spleen immunology, Spleen pathology, Thymidine metabolism, Tritium, Abortion, Spontaneous immunology, Cell Proliferation drug effects, Embryo Loss immunology, Glycopeptides pharmacology, Lymphocytes drug effects, Spleen drug effects
Abstract

Spontaneous proliferative activity of splenocytes in female CBA mice and the response of these cells to antigens of allogeneic male BALB/c and DBA/2 mice in a mixed splenocyte culture were evaluated by 3 H-thymidine incorporation in different pregnancy models. ♀CBA×♂BALB/c mating was used for modeling physiological pregnancy. Spontaneous abortions were reproduced by abortion-prone ♀CBA×♂DBA/2 mating. In order to simulate immunostimulant-induced and immunostimulant-potentiated abortions, 0.83 mg/kg muramyl dipeptide β-heptylglycoside was intraperitoneally injected to CBA females mated with BALB/c or DBA/2 males, respectively, on gestation days 5 and 7. The increase in the rate of embryo resorption in the models of spontaneous, induced, and potentiated abortions occurred against the background of an increase in the level of spontaneous proliferation of splenocytes and a decrease in their reactivity to paternal antigens on gestation day 9.

Published
2020
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2. [Immunoglobulin-positive cells in mouse bone marrow].

Author

Van'ko LV, Malaitsev VV, Khamitova NS, Bogdanova IM, and Fuks BB

Subjects
Animals, Bone Marrow Transplantation, Cell Count, Clone Cells, Male, Mice, Mice, Inbred CBA, Rats, Bone Marrow Cells, Hematopoietic Stem Cells, Immunoglobulins analysis, Lymphocytes immunology
Abstract

The content of Ig-bearing lymphocytes and their precursors in the mouse bone marrow was investigated 6 and 36 hours after the hydroxyurea treatment. Some increase of the B-cell content takes place in the trated bone marrow. Dividing and non-dividing B-cell precursors, except the stem cells, were practically absent.

Published
1978

3. [Simple method of detection of Fc receptor sites on cells].

Author

Malaĭtsev VV and Bogdanova IM

Subjects
Animals, Antigen-Antibody Complex, Humans, Mice, Staphylococcal Protein A immunology, Staphylococcus aureus immunology, gamma-Globulins immunology, Binding Sites, Antibody, Immunoglobulin Fc Fragments immunology, Immunoglobulin G immunology, Lymphocytes immunology, Rosette Formation methods
Abstract

A bacterial adhesion technique for identification of Fc-receptor bearing cells is based on the ability of Staphylococcus aureus, Cowan 1 strain, to form rosettes with cells previously treated with immune complexes or heat aggregated Ig G. The new technique is distinguished from other Fc-receptor detection methods by its simplicity and ease of detection of both immune complexes and aggregated IgG-binding cells.

Published
1979

4. Proliferative Activity of Mouse Splenocytes in Physiological Pregnancy and in Models of Spontaneous and Muramylpeptide-Dependent Abortions

Author

S. S. Obernikhin, A.A. Stepanov, M. N. Boltovskaya, I.I. Stepanova, Bogdanova Im, O. A. Svitich, K. A. Artem’eva, and O V Kalyuzhin

Subjects
Male, 0301 basic medicine, Primary Cell Culture, Gestational Age, Biology, Tritium, General Biochemistry, Genetics and Molecular Biology, Andrology, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Antigen, Pregnancy, medicine, Splenocyte, Animals, Lymphocytes, Crosses, Genetic, reproductive and urinary physiology, Cell Proliferation, Mice, Inbred BALB C, Macrophages, Glycopeptides, Abortion, Induced, Dendritic Cells, General Medicine, Induced Abortions, medicine.disease, Coculture Techniques, Embryo resorption, Abortion, Spontaneous, 030104 developmental biology, chemistry, Mice, Inbred DBA, Embryo Loss, Mice, Inbred CBA, Cba mice, Gestation, Female, Injections, Intraperitoneal, Spleen, 030217 neurology & neurosurgery, Muramyl dipeptide, Thymidine
Abstract

Spontaneous proliferative activity of splenocytes in female CBA mice and the response of these cells to antigens of allogeneic male BALB/c and DBA/2 mice in a mixed splenocyte culture were evaluated by 3H-thymidine incorporation in different pregnancy models. ♀CBA×♂BALB/c mating was used for modeling physiological pregnancy. Spontaneous abortions were reproduced by abortion-prone ♀CBA×♂DBA/2 mating. In order to simulate immunostimulant-induced and immunostimulant-potentiated abortions, 0.83 mg/kg muramyl dipeptide β-heptylglycoside was intraperitoneally injected to CBA females mated with BALB/c or DBA/2 males, respectively, on gestation days 5 and 7. The increase in the rate of embryo resorption in the models of spontaneous, induced, and potentiated abortions occurred against the background of an increase in the level of spontaneous proliferation of splenocytes and a decrease in their reactivity to paternal antigens on gestation day 9.

Published
2020

5. Dynamics of morphofunctional changes in immune organs of BALB/c mice with experimental hepatitis

Author

Bogdanova Im, S. S. Obernikhin, M. N. Boltovskaya, O. V. Makarova, and V. V. Malaitsev

Subjects
Male, medicine.medical_specialty, Pathology, Lymphocyte, Spleen, Thymus Gland, Lymphocyte Activation, General Biochemistry, Genetics and Molecular Biology, BALB/c, Hepatitis, Mice, Necrosis, Immune system, Internal medicine, medicine, Splenocyte, Animals, Involution (medicine), Lymphocytes, Cell Proliferation, Mice, Inbred BALB C, biology, General Medicine, biology.organism_classification, medicine.disease, Disease Models, Animal, medicine.anatomical_structure, Endocrinology, Liver, Hepatocytes, Periarteriolar lymphoid sheaths
Abstract

The time course of morphofunctional changes in the liver, thymus, and spleen was observed in BALB/c mice with Con A-induced experimental hepatitis. The progress of alterative changes in the liver was paralleled by intensification of accidental involution of the thymus. On day 1 of hepatitis development high proliferative and cytostatic activity of splenocytes was paralleled by hemorrhagic necroses and depletion of the peri-arteriolar lymphoid sheaths in the spleen (T-zones), presumably due to migration of activated lymphocytes to the liver and barrier tissues. Later normalization of lymphocyte proliferative activity was paralleled by recovery and hyperplasia of the splenic T-cell zones.

Published
2006

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