1. Multicenter evaluation of a rapid electrochemiluminescent adrenocorticotropic hormone (ACTH) immunoassay.
- Author
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Verschraegen I, Anckaert E, Schiettecatte J, Mees M, Garrido A, Hermsen D, Lentjes EG, Liebert A, Roth HJ, Stamminger G, and Smitz J
- Subjects
- Adrenal Gland Diseases blood, Adult, Aged, Aged, 80 and over, Female, Humans, Immunoassay instrumentation, Immunoassay statistics & numerical data, Luminescent Measurements instrumentation, Luminescent Measurements statistics & numerical data, Male, Middle Aged, Pituitary Diseases blood, Pituitary-Adrenal System metabolism, Pituitary-Adrenal System pathology, Reference Values, Sensitivity and Specificity, Adrenal Gland Diseases diagnosis, Adrenocorticotropic Hormone analysis, Immunoassay methods, Luminescent Measurements methods, Pituitary Diseases diagnosis
- Abstract
Background: Measuring plasma adrenocorticotropic hormone (ACTH) is a key step in the differential diagnosis of hypothalamic-pituitary-adrenal disorders., Methods: The recently developed electrochemiluminescence Elecsys ACTH immunoassay (Roche Diagnostics, Mannheim, Germany) was evaluated at six clinical laboratories on the Modular E170 and/or the Elecsys 2010 (Roche Diagnostics) immunoanalysers., Results: The within-run and between-run imprecision was
- Published
- 2007
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