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Your search keyword '"bis-iridoid glycoside"' showing total 2 results
Start Over Descriptor "bis-iridoid glycoside" Topic lignans
2 results on '"bis-iridoid glycoside"'

1. New Lignans and Iridoid Glycosides from Dipsacus asper Wall

Author

Xinguang Sun, Guoxu Ma, Dawei Zhang, Wenhua Huang, Gang Ding, Huagang Hu, Guangzhong Tu, and Baolin Guo

Subjects
Dipsacus asper Wall, lignans, bis-iridoid glycoside, Organic chemistry, QD241-441
Abstract

Six new compounds, including four new lignans, dipsalignan A (1), B–D (3–5), and two new bis-iridoid glycoside dimmers, dipsanosides M (7) and N (8), together with two known compounds (2) and (6), have been isolated from the roots of Dipsacus asper Wall. Their structures were established on the basis of spectroscopic data (MS, 1D, 2D NMR, and CD) and chemical methods. All the isolated compounds were tested against human immunodeficiency virus-1 (HIV-1) integrase inhibition activities, and only compounds 1, 2, 7, and 8 displayed weak activities.

Published
2015
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2. New Lignans and Iridoid Glycosides from Dipsacus asper Wall

Author

Guo-Xu Ma, Guang-Zhong Tu, Huagang Hu, Wenhua Huang, Xinguang Sun, Bao-Lin Guo, Gang Ding, and Dawei Zhang

Subjects
Iridoid Glycosides, Stereochemistry, Dipsacus asper, Human immunodeficiency virus (HIV), Pharmaceutical Science, HIV Integrase, medicine.disease_cause, Plant Roots, Article, Analytical Chemistry, lcsh:QD241-441, Dipsacus asper Wall, lcsh:Organic chemistry, Cell Wall, Drug Discovery, medicine, Organic chemistry, HIV Integrase Inhibitors, Physical and Theoretical Chemistry, chemistry.chemical_classification, bis-iridoid glycoside, biology, Organic Chemistry, lignans, Glycoside, Dipsacaceae, Integrase, chemistry, Chemistry (miscellaneous), HIV-1, biology.protein, Molecular Medicine, Two-dimensional nuclear magnetic resonance spectroscopy
Abstract

Six new compounds, including four new lignans, dipsalignan A (1), B–D (3–5), and two new bis-iridoid glycoside dimmers, dipsanosides M (7) and N (8), together with two known compounds (2) and (6), have been isolated from the roots of Dipsacus asper Wall. Their structures were established on the basis of spectroscopic data (MS, 1D, 2D NMR, and CD) and chemical methods. All the isolated compounds were tested against human immunodeficiency virus-1 (HIV-1) integrase inhibition activities, and only compounds 1, 2, 7, and 8 displayed weak activities.

Published
2015

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