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9 results on '"Saunier C"'

1. [Effect of acetazolamide on arterial blood lactate levels during recuperation in air from three days of hypercapnia].

Author

Saunier C, Horsky P, Hartemann D, and Colas T

Subjects
Acid-Base Equilibrium, Animals, Carbon Dioxide blood, Dogs, Hydrogen-Ion Concentration, Hypercapnia metabolism, Oxygen blood, Potassium blood, Pyruvates blood, Acetazolamide pharmacology, Hypercapnia blood, Lactates blood
Abstract

After a three day-period of hypercapnia, carbonic anhydrase blockade by acetazolamide inhibits the development of arterial blood alcalosis during the return in normal environment, and thus eliminates the transient increase in lactacidemia due to glycolysis stimulation.

Published
1975

2. Post-hypercapnia recovery in the dog: arterial blood acid-base equilibrium and glycolysis.

Author

Saunier C, Horsky P, Hannhart B, Garcia-Carmona T, and Hartemann D

Subjects
Acetazolamide pharmacology, Animals, Carbon Dioxide blood, Dogs, Female, Male, Respiration, Acid-Base Equilibrium drug effects, Glycolysis, Hypercapnia blood, Lactates blood, Pyruvates blood
Abstract

Changes in acid-base equilibrium and blood lactate and pyruvate concentrations were studied during recovery (breathing room air) after three days hypercapnia (FICO2 = 0.10) in awake dogs. Fast return to FICO2 = 0 produced a slight alkalosis in arterial blood and an increase in lactate and pyruvate concentrations which seemed to be maximum at the 15th minute. These changes were inhibited by previous injection of acetazolamide (50 mg/kg body weight). During progressive return to FICO2 = 0, over 1 hour, the peak value of blood lactate and pyruvate was delayed until the end of that hour, at the same time as a slight blood alkalosis appeared. These phenomen are most probably explained by a stimulation, due to alkalosis, of glycolysis at the level of phosphofructokinase.

Published
1977
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3. [Blood lactic acid level changes during acidosis induced by hydrochloric acid perfusion].

Author

Saunier C, Hennequin R, Hannhart B, Horsky P, Garcia Carmona T, and Colas T

Subjects
Acid-Base Equilibrium drug effects, Acidosis chemically induced, Animals, Dogs, Hematocrit, Hemoglobins metabolism, Hydrochloric Acid, Oxygen blood, Pyruvates blood, Acidosis blood, Lactates blood
Abstract

An increase in H+ ions concentration by infusion of hydrochloric acid produces a reduction in lactacidemia. This phenomenon is a result of the inhibitory effect of acidosis on phosphofructokinase producing a diminution of intracellular glycolysis.

Published
1975

4. [Blood lactate concentration, acid base and electrolyte equilibrium during muscular exercise for 20 minutes at various loads and at the "maximal power tolerated" in man].

Author

Gimenez M, Hennequin R, Horsky P, Colas T, and Saunier C

Subjects
Adult, Blood Gas Analysis, Carbon Dioxide blood, Hematocrit, Hemoglobins, Humans, Hydrogen-Ion Concentration, Male, Oxygen blood, Oxygen Consumption, Oxyhemoglobins, Partial Pressure, Spirometry, Acid-Base Equilibrium, Lactates blood, Physical Exertion, Respiration, Water-Electrolyte Balance
Published
1974

5. [Arterial lactate levels and pulmonary haemodynamics during moderate exercise in chronic respiratory insufficiency (author's transl)].

Author

Gimenez M, Romero Colomer P, Hennequin R, and Saunier C

Subjects
Acid-Base Equilibrium, Adult, Aged, Arteries, Blood Pressure, Bronchitis complications, Carbon Dioxide blood, Cardiac Catheterization, Chronic Disease, Heart Rate, Humans, Hydrogen blood, Kyphosis complications, Male, Middle Aged, Oxygen blood, Partial Pressure, Pneumoconiosis complications, Pulmonary Artery physiopathology, Respiratory Insufficiency blood, Respiratory Insufficiency etiology, Scoliosis complications, Silicosis complications, Tuberculosis, Pulmonary complications, Water-Electrolyte Balance, Hemodynamics, Lactates blood, Physical Exertion, Pulmonary Circulation, Respiratory Insufficiency physiopathology
Published
1974

9. Acid base and electrolyte equilibrium of arterial blood and cerebro-spinal fluid in respiratory insufficiency

Author

Monique Schibi, Marie-Claire Aug-Laxenaire, P. Sadoul, and Saunier C

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, Electrolyte, Hypercapnia, Cerebro spinal fluid, Chlorides, Internal medicine, Medicine, Humans, Respiratory system, Acid-Base Equilibrium, business.industry, Sodium, Phosphorus, Blood Proteins, Carbon Dioxide, Hydrogen-Ion Concentration, Water-Electrolyte Balance, Blood proteins, Endocrinology, Anesthesia, Lactates, Potassium, Arterial blood, Calcium, Acid–base reaction, Acidosis, Respiratory, medicine.symptom, business, Respiratory Insufficiency
Published
1969

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