1. Emergence and spread of novel H5N8, H5N5 and H5N1 clade 2.3.4.4 highly pathogenic avian influenza in 2020
- Author
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Thamer Al Kafagi, Jacqueline King, Azimkhan Tegzhanov, Timm C. Harder, Martin Beer, Anne Pohlmann, Sultanov Akhmetzhan, Ian H. Brown, Adam Brouwer, Talgat Karibayev, Scott M. Reid, Nikolay Zinyakov, Ashley C. Banyard, Ilya Chvala, Saduakassova Meruyert, Nicola S. Lewis, Steve Essen, Christian Grund, Ron A. M. Fouchier, Alexander M. P. Byrne, Victor Irza, Elliot Whittard, and Virology
- Subjects
0301 basic medicine ,Letter ,Epidemiology ,animal diseases ,Highly pathogenic ,030106 microbiology ,Immunology ,Zoology ,HPAI ,Biology ,medicine.disease_cause ,Microbiology ,Poultry ,Disease Outbreaks ,Russia ,03 medical and health sciences ,SDG 3 - Good Health and Well-being ,Virology ,Drug Discovery ,medicine ,emergence ,Animals ,Influenza A Virus, H5N8 Subtype ,SDG 2 - Zero Hunger ,Clade ,Phylogeny ,Netherlands ,Food security ,Influenza A Virus, H5N1 Subtype ,Whole Genome Sequencing ,avian ,virus diseases ,Outbreak ,General Medicine ,Influenza ,Kazakhstan ,Influenza A virus subtype H5N1 ,030104 developmental biology ,Infectious Diseases ,Migratory waterfowl ,Influenza A virus ,Influenza in Birds ,Iraq ,Eurasia ,Veterinary public health ,Parasitology ,Russian federation - Abstract
Analyses of HPAI H5 viruses from poultry outbreaks across a wide Eurasian region since July 2020 including the Russian Federation, Republics of Iraq and Kazakhstan, and recent detections in migratory waterfowl in the Netherlands, revealed undetected maintenance of H5N8, likely in galliform poultry since 2017/18 and both H5N5 and H5N1. All viruses belong to A/H5 clade 2.3.4.4b with closely related HA genes. Heterogeneity in Eurasian H5Nx HPAI emerging variants threatens poultry production, food security and veterinary public health.
- Published
- 2021