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Dynamics of specific antibody responses induced in mallards after infection by or immunization with low pathogenicity avian influenza viruses
- Source :
- Avian diseases. 54(1)
- Publication Year :
- 2010
-
Abstract
- Natural infections with different subtypes of low pathogenicity avian influenza viruses (LPAIVs) are very common in wild duck populations. Recent outbreaks of high pathogenicity avian influenza virus (HPAIV) H5N1 in Eurasian and African countries stimulated monitoring activities in aquatic wild bird populations. Surveillance mainly focused on virus detection. Only a few serologic investigations have been conducted so far, although such data may retrospectively elucidate epidemiologic patterns of different AIV subtypes in the populations under study. To better understand the immunologic and serologic reactions of mallards after infection with LPAIV, we investigated the AIV type- and subtype-specific antibody dynamics in mallards after different LPAIV infections by hemagglutination inhibition, competitive enzyme-linked immunosorbent assay, and western blot analysis, as appropriate. Four groups of mallard ducks were used: 1) naturally infected birds, 2) birds that were experimentally infected with LPAIV, 3) birds that were immunized with inactivated virus preparations, and 4) negative control birds. Ducks were monitored for up to 15 mo, and serum samples were investigated every 1-4 wk. It could be shown that infection with LPAIV in mallards can be traced serologically over prolonged periods of time.
- Subjects :
- animal structures
Hemagglutination
animal diseases
medicine.disease_cause
Antibodies, Viral
Serology
Microbiology
Food Animals
Immunity
medicine
Animals
Hemagglutination assay
General Immunology and Microbiology
biology
virus diseases
Outbreak
Viral Vaccines
Building and Construction
Virology
Influenza A virus subtype H5N1
Ducks
Immunization
Influenza Vaccines
Influenza in Birds
biology.protein
Animal Science and Zoology
Antibody
Influenza A Virus, H5N2 Subtype
Subjects
Details
- ISSN :
- 00052086
- Volume :
- 54
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Avian diseases
- Accession number :
- edsair.doi.dedup.....281539c7ffc0e6b52341ebe8538c193e