1. Redox-Driven Host-Guest Interactions Allow the Controlled Release of Captured Cells on RGD-Functionalized Surfaces
- Author
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Didier Boturyn, Liliane Coche-Guérente, Pierre Labbe, Pascal Dumy, Dhruv Thakar, Jérôme Dejeu, Michael Claron, Christiane H. F. Wenk, Département de Chimie Moléculaire - Ingéniérie et Intéractions BioMoléculaires (DCM - I2BM), Département de Chimie Moléculaire (DCM), Université Joseph Fourier - Grenoble 1 (UJF)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université Joseph Fourier - Grenoble 1 (UJF)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'études dynamiques et structurales de la sélectivité (LEDSS), and Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
Scaffold ,Metallocenes ,Surface Properties ,Nanotechnology ,Cell Separation ,Peptides, Cyclic ,Biochemistry ,Redox ,chemistry.chemical_compound ,Humans ,[CHIM]Chemical Sciences ,Ferrous Compounds ,Bifunctional ,Molecular Biology ,ComputingMilieux_MISCELLANEOUS ,Microscopy ,Chemistry ,Ligand ,beta-Cyclodextrins ,Organic Chemistry ,Quartz crystal microbalance ,Integrin alphaVbeta3 ,Controlled release ,HEK293 Cells ,Quartz Crystal Microbalance Techniques ,Molecular Medicine ,Multivalent binding ,Oligopeptides ,Oxidation-Reduction - Abstract
A quartz crystal microbalance technique with dissipation monitoring and a complementary optical microscopy technique were used for monitoring the capture and release of specific cells on a surface displaying a bifunctional molecular device, composed of a molecular scaffold endowed with the cell recognition property of an RGD ligand and a β-CD/Fc redox-switchable system.
- Published
- 2014