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171 results on '"Joshua C. Bis"'

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1. Methylation patterns associated with C-reactive protein in racially and ethnically diverse populations

2. Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

3. Admixture mapping implicates 13q33.3 as ancestry-of-origin locus for Alzheimer disease in Hispanic and Latino populations

4. Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed

5. Association of mitochondrial DNA copy number with cardiometabolic diseases

6. Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity

7. Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing

8. Genomic Studies Across the Lifespan Point to Early Mechanisms Determining Subcortical Volumes

9. Associations of carotid intima media thickness with gene expression in whole blood and genetically predicted gene expression across 48 tissues

10. Association of low-frequency and rare coding variants with information processing speed

11. Rare genetic variants explain missing heritability in smoking

12. Genome-wide association study of circulating interleukin 6 levels identifies novel loci

13. Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes

14. Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate

15. A framework for detecting noncoding rare variant associations of large-scale whole-genome sequencing studies

16. Whole genome sequence analysis of blood lipid levels in >66,000 individuals

17. Multiethnic Genome-Wide Association Study of Subclinical Atherosclerosis in Individuals With Type 2 Diabetes

18. Genome-Wide Association Study of Apparent Treatment-Resistant Hypertension in the CHARGE Consortium: The CHARGE Pharmacogenetics Working Group

19. Large‐scale sequencing studies expand the known genetic architecture of Alzheimer's disease

20. A system for phenotype harmonization in the National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) program

21. Rare coding variants in 35 genes associate with circulating lipid levels – a multi-ancestry analysis of 170,000 exomes

22. Whole genome sequence association analyses of brain volumes in the TOPMed program

23. Stroke

24. Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

25. Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

26. Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

27. Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

28. Genetic Variants Associated with Circulating Parathyroid Hormone

29. Allelic Heterogeneity at the CRP Locus Identified by Whole-Genome Sequencing in Multi-ancestry Cohorts

30. Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

31. Inherited causes of clonal haematopoiesis in 97,691 whole genomes

32. A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

33. Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

34. Genome-wide meta-analysis of SNP-by9-ACEI/ARB and SNP-by-thiazide diuretic and effect on serum potassium in cohorts of European and African ancestry

35. Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies

36. Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci

37. 52 Genetic Loci Influencing Myocardial Mass

38. Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis

39. Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia

40. Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk

41. Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

42. Whole genome sequence association with E-selectin levels reveals loss-of-function variant in African Americans

43. The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE)

44. Lp-PLA2, scavenger receptor class B type I gene (SCARB1) rs10846744 variant, and cardiovascular disease

45. Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

46. O3‐06‐01: WHOLE EXOME SEQUENCING STUDY IDENTIFIES RARE COPY NUMBER VARIATIONS FOR LATE‐ONSET ALZHEIMER'S DISEASE: THE ALZHEIMER'S DISEASE SEQUENCING PROJECT CASE‐CONTROL ANALYSIS

47. Quality Control and Integration of Genotypes from Two Calling Pipelines for Whole Genome Sequence Data in the Alzheimer’s Disease Sequencing Project

48. Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

49. Transethnic Evaluation Identifies Low-Frequency Loci Associated With 25-Hydroxyvitamin D Concentrations

50. Multi-ethnic genome-wide association study for atrial fibrillation

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