1. Predictors of delayed breast reconstruction in the Netherlands
- Author
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Marc A.M. Mureau, K. M. de Ligt, L. de Munck, Sabine Siesling, L.S.E. van Egdom, Hinne A. Rakhorst, L.B. Koppert, Plastic and Reconstructive Surgery and Hand Surgery, Surgery, TechMed Centre, and Health Technology & Services Research
- Subjects
Adult ,medicine.medical_specialty ,Mammaplasty ,medicine.medical_treatment ,Breast Neoplasms ,Logistic regression ,Breast cancer ,SDG 3 - Good Health and Well-being ,Internal medicine ,medicine ,Humans ,Pharmacology (medical) ,Radiology, Nuclear Medicine and imaging ,Stage (cooking) ,Mastectomy ,Netherlands ,Proportional hazards model ,business.industry ,General Medicine ,Middle Aged ,medicine.disease ,Cancer registry ,Radiation therapy ,Oncology ,Female ,business ,Breast reconstruction ,Follow-Up Studies - Abstract
Purpose Delayed breast reconstruction (DBR) is a valid option for postmastectomy breast cancer patients who have a desire for breast reconstruction but are not considered suitable for immediate breast reconstruction (IBR). The objective of this study was to investigate the clinical practice and predictors of the use of DBR in the Netherlands. Methods Stage I–III breast cancer patients diagnosed from January to March 2012 and treated with mastectomy were selected from the Netherlands Cancer Registry. Routinely collected patient, tumor, treatment and hospital characteristics were complemented with data about DBR up to 2018. Multivariable logistic regression analyses were performed to identify factors independently associated with postmastectomy DBR. Factors associated with time to DBR were identified through Cox regression analyses. Results Of all patients who underwent mastectomy (n = 1,415), 10.2% underwent DBR. DBR patients more often received autologous reconstruction compared to IBR patients (37.5% vs 6.2%, p Discussion The use of DBR after mastectomy could not be fully explained by age below 50 years, chemotherapy, and hospital volume. Treatment with radiotherapy and adjuvant chemotherapy increased time to DBR. More information about patient preferences is needed to understand the use and timing of reconstruction.
- Published
- 2022